Trichomycterus rosablanca: 134325658 Help Entry 134325658         CDS       T09921                                  Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism trn  Trichomycterus rosablanca Pathway trn04020   Calcium signaling pathway trn04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:trn00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     134325658    04020 Calcium signaling pathway     134325658  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:trn04040]     134325658 Ion channels [BR:trn04040]  Voltage-gated cation channels   Ryanodine receptor    134325658 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  134325658 NCBI-ProteinID:  XP_062863974 LinkDB All DBs Position 13:7410767..7645920 Genome browser AA seq 4891 aa AA seqDB search MAEGGEAEDEIQFLRTDDEVVLQCVACIQKENRKFCLSAEGLGNRLCYLEPTSDAKNVPP DLAICNFVLEQSLSVRALQEMLAKTGQNNEAAHGGGHRTLLYGHAILLRHSFSGMYLACL KTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLH LSISTGNIQVDASFMQTLWNVHPTCSGSSVEEGYLLGGHVMRLFHGHDEVLTIPGSDQSE EQQRIVNYETGKVGAKARSLWRLEPLRISWCGSHIRWGQPFRLRHLTTGHYLALAEDKGL VLQDREKSDTTSTAFCFRASKEKLESSPKRDIEGMGVGEIKYGDSLCFVMHMATSLWLSY QALDVKSTRLGPLKRQACLHAEGHMDDGFTLQRCQHEESCAARIIRNTTRLFSHFIRDLD SLAGKNRMASVLLPIEEVLQTLNDLITYFQLPDAELEHEEKQIKLRSLKNRQNLFKQEGM LTLVSNCIDRLSVYNNAAHFGECAGEEAAMAWKDILNLLYELLAALIRGNRNNCTQFSQN LDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVL CSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVREGSAQYKKWY FELMIDQVEHFITSEPSHLRVGWASTKGYAPYPGGGEGWGANGVGDDLYSYGFDGLHLLS GRIPRRVASVNQHILTSDDVVSCCLDLAAPSISFRINGQPVQGMFESFNTDGLFFPVVSF SAGAKVRFLLGGRHGDFKFLPPSGYAPCYEALLPKEKMRVEPVKEYKRDIDGVRDLLGNT QFLSQASFIPTPVDTSQIVMPPHLEKVRDRLAENIHELWAINKIELGWSYGKIRDDNKRH HPCLVDFSKLPETERNYNLHMSTETLKTLLALGCHVLQVSVNAEEDLKKMKLPKNYMMSN GYKPTPLELSEVKLTPAQELLVEKLAENAHNVWAKDRVKQGWTYGIQQDLKSKRNPRLVP YAFLDERTKKSNRDSLREAIRTLIGCGYSIEPPDQEGAHVVEKLSIDKIRFFRLERTYAV RTGKWYFEFEAVTGGDTRVGWARPGVRPDVELGTDDQAFVFDGFKGHRLHQGSRLFGRCW HAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFIPVCSLGLSQVGRMN LGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVDVPKDQSHIAVTRIDGT IESPPCLKVTHKTFGTQTSNADMVFCRLSMPVEFHSTFKSVPVIDMNGLYDEETLKVKYR YPVKSMKHVDEGRRTDYSNITSYYHSVRIFAGQDPSCVWVGWVTPDYHYYSNYFNLSKNR TVTVTLGDERGRVHESVRRSNCYMVWGGDVVSSSHSSSRSNVDLEIGCLIDLATGLVTFT INGREISTSHQVEPNTKLFPAVFIRPTSPNLFQFELGKIKNSMPLSSAIFKSEHKNPVPQ CPPRLDVQTIKSVLWSRMPNTFLKVETARVSERHGWQVQCIEPLQMLAVHIPEENRCVDI MELSEQEDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYIIDNQYLSGMLRQG FYDALLSIHLETAKAARLMMNNEFIIPITAETRSIRLFKDPSKHHQPPGVGLSTSLKPRL SFAPPCFITPKRDQHLYSPEIPLDILREKAICMLAEAVQGGGDHIRDPVGGSVEYQFVPV LRLISTLLTMGVLTSLDVHKILLLIEPNVFGEQKEDEVGEATMKEGMTRAEEKAVEAGEE EAKEPKQPIKGLLQKRLPESVKLQMCELLQYFCDCELRHRIEAIVSFSDSFVSKLQYNQK FRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLNFSMGEDCPCPEDIQEELYDFHNE LRLHCGIPMEEEEGEQNMSIKGRLLALVYKIKGQPHRAEQQPTENEQTAPSNLKELISQT MVSWAQESHIQDPELVRVMFSLLRRQYDSIGELLRAMRKSYTISAASVQDTIHLLASLGQ IRSLLSVRMGKEEEQLMIDGLSDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGGKSQ EIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDVAAS SMMDNNSLALALEEPDLDKVVTYLAGCGLQSCPMLLAKGYPDIGWNPIEGERYLSFLRFA VFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETPALDLPGTA QGLVSTEDDEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRVRAILRSLV PMEDLVGIISIPLKMPVVNKDATVTEPDMSACFFPDHKAPMVLFLDRVYGIEDQSFLLHL LEVGFLPDLRAAASLDTEALRTTETALAMNRYIGTAMLPLLTRCAPHFAGTEHHVTLIDS TLHTIYQLSKGSSLTKAQRDAIEECLLAVCKYLRPSMLQQLLRRLVFDVPLLPEYCKMSL KLLTNHYEQNWKYYCLPSGWGSYGMASEEELLLTKKIFWGIFDSLSQNKYEQELFKMAMP CLSAIAGALPPDYVDCSLSATLEKPVSVDAQGNFDPRPICTANISLPEKLEHVTHKYAEH SHDKWSAEKVVLGWKYGDTIDEKSKTHPMLRSYKSLTEKEKDVYRCPVKESLKSMLAMGW NVDRTKDGEAMFQQRETEKMRKISQTSQVNVDCGFNPSPVDMSNVLLSRELQAMVDVVAE NYHTIWARKKKTDLGAKGGGTHPLLVPYDTLTAKEKARDREKAQDLFRFLQINGYVITRG FKDMEQDSSSMEKRFAYKFLKKLLKYVDFAQEFIAHLDGKGSCGKNDRSPHEQEIKFFAK VLLPLIDQYFKNHSLYFLSSPSKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFGSD SATMVSCLHILAHTLDTRTVMKSGSELVKSALRTFFENAADDLEKTLENLKLGKFTHSRS QMKGVSQNINYTTVALLPILTALFEHITEHQFGVDLLLDDVQLSCYRILNSLYSLGTGKN IYVERQLPALGECLATLAGAMPVAFLEPHLNIHNPYSVFNSKTARERAILGMPSMVEEMC PEVSHLDCLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLSYWWERGTENQAKSLTTVC STTVTSEHLSIILGNILKILNNNLGIDEASWMKRIAVYAQPIISKARKDLLKTHFLPTLE KLKKKTVKVVSEEELLKADCKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRW LKEPDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDSKTKMSKAGG QDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYGLKDTDEE VKEHLRQNMHLQEKSEDPAVRWQLHLYKDVIVKNEGPPDPERTVDRLQTISAAVFHLEQM LSKFALSLYLLVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLTGY QRIWIETETYSFEEKLVQDLAKQGVEEEEEEVAEMQPDPLHQLILHFSHNALTERSSLDE DLLYIAYADMMAKSCAEDENEDEEGKEKTFEEKEMEKQKTLYQQARLHDRGAAEMVLQMI SASKGWLGPMVTFTLKLGISNLNGGNILVQQKMLDYLKEKRDVGFFKSLSGLMQSCSVLD LNAFERQNKAEGLGMVTEEGSSSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGN TTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEAGQRNFSKALAVAKQIFNSLTEYI QGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMMLS LLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDSFKEHDSDGKGIIS KREFQKSMENQKQYSQSEIEFLLSCVEADENDLFNYVEFVKRFHEPAKDIGFNVAVLLTN LSEHMPHDSRLATFLNLAESVLNYFEPFLGRIEIMGGAKRIERVYFDISESSRTQWEKPQ VKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASLISEPDAVERKEGDENLHSV THEPEEEHEDVMLESSSAFTMACVSMRKNFCTLGKLLTLKSLKKQYKKLRKMSLREMICG FLTFFWTIFFGIFRFLYNLVWGFFHILWSTMFGGGLVEGAKNMKVTDILGNMPDPTQFGI HGDVLETDKLEVNETSLVAEIGQLAEADNEEMDLMSELLSIQPKKEGGKHGTEPGLGDLS EVAGVDSPSSLAAAVRQKKAQEAATKSTETETKSETEKADTEYGEKRDKDKATESPTKRT SDKKRKPPKRRCGLKKEPPEAIMASFFAGLDIYQTKILNYLARNFYNLRFLALFVAFAIN FILLFYKVITIVLLNVQNCPYFSYSEEVDSWTGRGDEEEVGIEYFVLQENTGYMAPTLRF LAVLHTIISFLCVVGYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLV INTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEETIAKEASLVT WLSSIDTKYHIWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTI LSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSENEDEPDMKCDDMMTCYLFH MYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQ QEQVKEDMETKCFICGIGNEYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQ ESYVWKMYQERCWDFFPAGDCFRKQYEDQLN NT seq 14676 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggcggggaagcggaagacgagatccagtttttacgcacggacgatgaagtg gtgttgcagtgtgtggcctgtatccagaaggagaatcgcaagttctgcctgtctgctgag ggactcggaaatcggctgtgttacttggagcccacttcagatgccaagaatgttcctcca gaccttgcaatctgcaactttgtgctggagcaatctctttctgtgcgagcactgcaggaa atgctggccaaaaccggtcaaaataatgaggcagcccatggaggtggacacaggacacta ctgtatggacacgctatccttctgcggcactccttcagtggaatgtacctggcttgttta aagacttccaggtctttgacagataagctgtctttcgatgtgggacttcaggaggactca acaggtgaggcttgttggtggactattcaccctgcttctaagcagagatccgaaggggaa aaggtccggattggtgatgaccttatccttgttagtgtatcatctgaacgctatcttcat ttgtccatctccactggcaatattcaggtggatgcctcctttatgcagacactgtggaac gtccaccccacatgttcaggcagcagtgtggaagaaggatatctccttggaggccatgtg atgcgtttgtttcatggccacgatgaggttttgacgatccctggttcagatcagagtgag gaacagcagagaatagtcaactatgagactggaaaagtaggcgccaaggccaggtctctc tggagattggaacctctacggatcagttggtgtggcagtcatatccgctgggggcagccc ttccgcctgcgtcacctcactaccgggcactatctggccctggctgaagacaagggtctt gtgctgcaggacagagagaaatctgacacaacctctactgccttctgctttcgagcatcc aaggagaagctggagtcgagcccaaagcgagatattgagggtatgggagttggggagatt aagtatggagactcgctctgttttgtaatgcacatggcaacgagcctgtggctctcgtac caggcactagatgtgaaatcgacacgtttggggcctctcaaaagacaggcctgccttcat gcagaaggacacatggatgatgggttcacgcttcagcgctgtcagcatgaagagtcgtgc gctgcacgcatcatacgcaacactaccaggctttttagccatttcattagagacctggac agtctggctggaaagaatcgtatggcttcagttcttctacctatcgaggaagttctccag actcttaatgacctcatcacgtatttccaacttcctgatgctgagctcgaacatgaggag aagcagatcaagctgcgatcgcttaagaaccgacagaacctcttcaaacaggaggggatg ctgactttggtttctaactgcatcgatcgcttgagtgtgtacaacaatgctgcacacttc ggagaatgtgccggagaggaggctgccatggcgtggaaagatatactcaacctgctctat gagcttcttgctgctctgatcagaggaaacaggaacaactgcactcaattctcccaaaac ctggactggctggtcagcaagctggagagactggagtcgtcctcagggatcctggaggtt ctccactgcatcctaattgagagcccagaggcacttaacatcatccaaagaggacacatc aaatcaattatctcacttctatataaacacggtcgcaaccacaagatcttagatgtgctt tgctctctctgtgtttgtaatggagtggctgtgagagccaatcaaaacctcatctgtgat catttgctcccaaagagagacctgttgctccagacaagattggttaatgatgtccaaagc atgagacctaacatctttttgggtgtacgagaaggttcagctcagtacaagaagtggtac tttgagctgatgatagaccaagtggagcacttcatcaccagcgaaccttctcacctgcgg gtcgggtgggcctccaccaaaggctatgcaccttacccagggggtggagaaggttggggg gccaacggagttggggatgacctctattcttatggcttcgatggacttcacttgttgtca gggcgaatccctcggagagtggcttcagtaaaccagcacatccttacgtccgatgacgtg gtcagctgctgcttggatttggctgcccccagcatctcattcaggatcaatggacagccg gttcaaggcatgttcgagagctttaacaccgacggcctcttctttcctgtggtcagcttc tctgctggtgctaaggtacgtttccttttgggcggtcgccacggagacttcaagttcctg ccaccgtcaggctatgcaccatgctatgaagcactgctccctaaagaaaagatgcgagtg gagcctgtaaaggaatacaaaagagatatagatggcgttagagacctgctgggcaacaca cagttcctgtcgcaggcctctttcatacccacaccggtggacacctctcagattgtcatg ccacctcacctggagaaagtgcgtgaccgtctggcagagaatatccatgaactgtgggcc ataaacaagatcgaactcggctggtcttatggaaagataagagacgataataaaagacac catccctgtctggtggatttctccaagctgcctgaaactgagaggaattacaacctgcat atgtcaactgagacgttaaagactctcttggctctgggctgccatgtgcttcaggtcagt gtcaatgctgaagaggacctgaaaaaaatgaagctcccaaagaactacatgatgtcaaat ggctacaagcccacaccgctggagctgtctgaagtaaaactgacccctgcacaagagctg ttggtggaaaagttggctgagaacgcacacaatgtttgggccaaagatcgggtcaaacaa ggctggacttacggcatacagcaggatctgaagagcaagcgcaatcctcgtcttgtgccg tatgcgtttcttgacgagcgcaccaagaagtcaaaccgtgacagcctacgcgaagccatc cgaacactaattggatgcggctacagcatcgagcctcctgaccaggaaggggctcatgtg gtggagaagctgagcattgacaaaattcgattcttccgtttggagaggacatacgcagtg agaacaggaaagtggtattttgagttcgaggctgtgactggaggagacacgagggtcggt tgggctcggccaggcgtgcggcccgatgtggaactgggaactgatgatcaggcatttgtc tttgatggatttaagggccatcgtctccaccaaggcagccgtttgtttggccgctgctgg catgccggtgacgtggtgggctgcatgatcaacatggaagacaagtccatgatttttaca ctcaatggagaaatccttatcacaaacaagggctctgaactctgctttgctgactttgag actgaggatggctttattcccgtttgcagcctgggcctttctcaagtcggacggatgaac ctcggcaaagatgccagcacctttaaatattacaccatgtgtggcctgcaggagggattt gaaccctttgctgtcaacatgaaccgtgaggtcaccatgtggtttagcaaacgccttcct acttttgtcgatgtacccaaagatcaaagtcatattgcggttacaaggattgatggcact atcgagagccctccatgtctgaaggtcacacacaagacatttgggacacagaccagcaat gcagacatggtgttctgtcgtctgagcatgcccgtggagttccattcaaccttcaaaagt gttcctgtaatcgacatgaatggactgtatgacgaggaaacactcaaagttaaatataga tatcctgtgaaatcaatgaaacatgtagatgaagggagaagaacagactatagtaacata acaagttactaccactctgtcagaatatttgctggacaggatccctcatgtgtgtgggtt ggctgggtcacacctgactaccattactacagcaactactttaacctcagcaagaaccgg accgtgacagttacactaggggatgagcgaggccgggtccatgagagtgtgagaaggagt aactgctacatggtgtggggaggtgacgtcgtcagctccagtcattcatccagcaggagt aatgtagatttagagattggctgtctcattgatttggctactggtttagtgactttcacc attaatggtagagaaatttcaacttcacatcaggtggaaccgaacacaaaacttttccct gctgtgttcatacgcccaaccagtccaaatcttttccaatttgaactgggaaaaatcaag aacagtatgcctctgtcatcagccatcttcaagagcgagcacaagaacccagtccctcag tgtcctcctcggctggacgtccagaccatcaagtcggtgctgtggagtcggatgcccaac accttcctgaaggtggagacggctcgagtgagtgagcgacatggctggcaggtgcagtgt atcgagcctctgcagatgctggctgttcacattccagaggaaaaccgatgtgtggatatc atggaactgtctgaacaggaagacctgcgcaagttccattatcacaccttgaagctctac tgtgccctctgtgcactaggtaacacccgtgtagctcatgctctttgcagtcaccttgac caatcacagcttctctatatcatcgacaaccaatacctgtctggcatgctgcgccaaggc ttctacgatgctctcctcagcattcacctagagacggccaaagctgcccggcttatgatg aacaacgagttcatcatccccattactgcagagactcgcagtattcgactctttaaggat ccttccaagcaccaccaaccacccggtgtaggactcagtacatccctaaaacccagactt agctttgctccaccgtgcttcattactcccaagcgtgaccaacatctctatagccctgaa attcctttggacattctgcgggagaaagcaatttgcatgctagctgaggccgttcagggt ggaggagaccatattcgagatcctgtagggggcagtgtggaatatcagtttgtgccagtt ctaagactgataagcacgctcctaaccatgggtgttctgacgagcttggatgttcacaag attttgcttctcatcgagccgaacgttttcggagagcagaaagaggatgaagtgggggaa gctacgatgaaggaggggatgaccagagcagaggagaaggcggtggaggctggggaagag gaagccaaagaacccaagcaacccattaaaggacttttacagaaaagactgccagagtca gtcaaactacagatgtgtgaacttcttcagtacttctgtgactgtgagctaaggcaccgt atcgaggccatcgtctctttctctgacagctttgtgtcaaagctgcagtacaaccagaag tttagatacaacgagttaatgcttgctctcaacatgtcggctgctgttacagccaaaaag accaaggagttccgctcaccgcctcaggaacagattaatatgctgttgaacttcagcatg ggagaggactgtccatgtcctgaggacattcaggaggagctctatgatttccataatgag cttcgtttacactgcggtattcctatggaggaggaggagggtgaacagaacatgtccatt aagggccgtctgctggctttggtttacaagatcaagggacagccacacagagcagaacag cagcccacagagaatgaacaaacagccccttccaacttgaaggagctgatatcccagacc atggtgagctgggctcaagagagccacatccaggacccggagctggtgcgtgtcatgttc agccttctgcggcgccagtatgacagcattggtgagctgctacgtgccatgcgcaagagc tacaccatcagtgccgcctctgtgcaagacaccattcacctcctggcctcgctgggtcag atccgctcactgctcagtgtccgcatgggcaaagaggaagagcagctcatgatcgatggc cttagtgacatcatgaacaataaggtgttctaccaacatcccaacctgatgagagtactg ggaatgcacgagactgtcatggaggtgatggtgaatgtgctcgggggaggaaagtctcag gaaatcgcgtttcctaaaatggttgccagctgctgtcgctttctgtgctacttctgtcga atcagccgtcagaaccagaaggctatgtttgatcacctgagttacctgcttgagaacagc agtgtgggcttggcttctccatcaatgagaggctccacgcctctggatgtagctgcttcc tccatgatggacaacaacagcctggcactcgcattggaagagcctgacctcgacaaggtg gtcacatatttggctggctgtgggctgcagagttgtcccatgctgcttgctaagggttac ccagacataggctggaacccgattgagggagaacgctacctctccttcctccgttttgct gtctttgtcaatggtgagagtgttgaagagaactccagtgtagtggtgaaactgctgatt cgtcggcctgaatgctttggtcccgccctgcgtggcgagggtggaaacggtctgctagca gccatgaaagaggccattaaaatatcagagaccccagcacttgacttgcctggcactgcc cagggccttgtgtctactgaggatgatgaggaggaagaggtggtccatatgggaaatgcc atcatgtccttctactctgcgcttattgatctgctaggacgttgtgcacctgaaatgcat ctgatcaataaggggaaaggggaggctctgagagttcgtgccattctgcgttctttggtg cctatggaggacctggttggcatcatcagcatccctcttaaaatgccagttgtcaataaa gatgctactgtgactgagcccgacatgtctgcctgtttcttcccggaccacaaggcaccc atggtgttgtttctggatcgggtctatggaatcgaggaccagagctttctgttgcatttg ctggaagtcggctttctgcctgacctccgagctgcagcctcccttgacacagaagctcta agaaccacagagacagctctggctatgaatcgctacattggtacagctatgctgcctttg ctgactcgctgtgcccctcactttgctggtacagagcatcacgtcacgcttatcgactcc acactccacacaatctaccagctcagcaagggttcctcactcaccaaggcccagagagac gccatcgaggagtgcctgctggccgtctgcaagtacttgaggccttcaatgctccagcag ttgctgcgtcgtctggtgtttgacgtgcctttgctccctgagtactgcaagatgtctctt aagcttttgacaaatcattatgagcaaaactggaaatactactgcctgccctctggttgg ggcagttatggcatggcctctgaggaggagctgcttctcactaagaagatcttttggggc atctttgattctctctcccaaaataagtacgagcaggagctgtttaagatggccatgccg tgtctgagtgctattgctggagcgctgccgccagattatgtggactgttctcttagtgcc acactggaaaagccagtctctgtggatgcacagggcaactttgacccccggcccatctgc acagccaacatctctctcccggagaagctggagcatgtcactcacaaatatgccgaacat tcccatgataaatggtctgctgagaaggttgttctgggatggaaatatggagataccatt gatgaaaaatctaaaacacatcccatgctaagatcctacaagtcactaacagagaaggaa aaggatgtttaccgttgtccggtgaaggagagtttaaagagtatgcttgcaatgggttgg aacgttgacaggaccaaagatggagaggccatgtttcagcaaagggagactgagaagatg cgtaaaatctcacagacctcccaggtaaatgttgactgtggattcaacccaagtccagta gacatgagcaatgtgttgctgtctcgagaattgcaggcaatggtagacgtggtggctgaa aactaccacaccatttgggccaggaaaaagaagactgacctaggagccaaaggtggagga acacatcccttgctggtgccatatgatactcttacagcgaaagagaaagccagagaccgc gagaaagcccaagacttgtttcgcttcctgcagatcaatggttatgtcattacccgagga tttaaagacatggagcaggactcgtcctcaatggaaaaaaggtttgcttataagttcctg aagaagctgctgaaatatgtggactttgcacaggagttcattgcacatctggacggaaag ggtagctgtggaaaaaatgaccggtctcctcatgagcaagagatcaagttctttgcaaag gtgcttttacctctcatagaccaatacttcaaaaaccactctctctacttcctctcctct cccagcaaaaacctgagcagcagtggttatgcttccaacaaagagaaagagatggtcacc agccttttctgtaagctggctgctcttgttagacacagaatctcattatttggaagtgac tcggccactatggttagctgtcttcacatccttgcacacacacttgataccagaacagtg atgaagtctggctccgagctggtgaagtcagcattgagaacattctttgagaatgcagca gatgatttggagaagacattagagaacctgaagcttgggaagtttactcactcacgtagc cagatgaagggtgtatcacagaacatcaactacaccactgtggctctgctgcccatactt actgccctgtttgagcacatcactgagcatcagtttggagtggaccttctattggatgat gtccagctgtcatgttaccgaatcctgaatagcctgtactctttgggaactggaaagaac atatatgttgaaagacaacttccagctctaggtgagtgtttggccaccctggcaggagcg atgcctgtggcttttttggagcctcacctcaacatacacaacccttactctgtctttaac tccaagacagcacgagaacgggcaatcttgggcatgcccagcatggtagaagagatgtgt ccagaagtgtcacatctggactgcctgatgaaggacatcaatgacatgtctgagtcaggc gctcgctacacagaaatgcctcatgttattgaggtggtacttcccatgctgtgtaactac ttatcctactggtgggagcgtggcacagagaaccaggccaagagcttaacgactgtgtgt agcaccacggttacctctgaacacctgagcatcatcctggggaacatccttaaaatcctg aacaacaatctgggcattgatgaggcctcatggatgaagaggatagctgtgtatgcccag cctatcatcagcaaggcaagaaaggaccttttaaagacacacttcctgcccactctggaa aagttaaagaagaagacagtgaaggttgtttcagaggaagagcttctgaaagctgactgc aagggcgacactcaagaggcagagctgctgatcctggatgagtttgcagtgttgtgcaga gacctatatgccttttatcccatgcttattcgctatgtggataacaacaggtcacgatgg ctgaaggagccagatgccgattccaatgagctcttcaggatggtagcagagatctttata ctttggtgcaagtcacataatttcaaaagagaggaacaaaactttgtggtgcagaatgaa atcaataacctctccttcctcactggggacagcaaaaccaagatgtcgaaggcaggagga caggaccaggaaagaaagcacaagaaacggcgtggtgaattttactccatccagacctca ctcattgtggctgctctaaagaagatgttgcccattggcctgaacatgtgcacgcctgga gaccaggaacttatttcgttggccaagacgcgatatggtttgaaagatacagatgaagag gttaaggagcatttaagacagaacatgcacctgcaggagaagtcggaagaccctgctgta aggtggcagctccacttgtataaagatgtgattgtgaaaaatgaaggcccacctgatcca gagcgcacggttgatcgtcttcagaccatctcagctgctgtgtttcacctagagcagatg cttagtaaatttgctttgtctttatatttactggtggaacaaccactaaggtccaagaag tgtgtgtggcagaaactactgtctaaacagcgaaagcgtgcggtagtggcctgcttccgc atggcacccttatacaacctgcccaggcatcgttctattaacctgttcctcacgggctat cagagaatatggatagagacagagacctactcgtttgaagagaagctagtgcaggatttg gcaaaacaaggagtcgaggaggaagaagaggaagttgctgaaatgcagccagaccctctt caccagcttatcctgcactttagtcataatgctctgacagaaaggagttccctagatgag gatttgctgtacatagcatatgcagacatgatggcaaagagttgtgctgaagatgagaat gaggatgaagaaggaaaagaaaaaacatttgaggaaaaggaaatggaaaaacagaagaca ttgtatcagcaggccaggttacatgaccgtggagctgctgagatggttttacagatgatc agtgccagcaaaggttggttgggtcccatggtaaccttcactctaaagctgggcatctca aatctcaatgggggcaacattttagttcagcagaaaatgctggattatctaaaggaaaag cgagatgttggctttttcaaaagtctgtcaggacttatgcaatcatgcagtgtgttagat ctaaatgcatttgagaggcaaaacaaagctgaaggtctgggcatggttactgaggaaggt tcaagttccaaggtgctccagaatgatgagtttactaaagatttgtttaggttcttgcag cttctctgtgagggtcataacaacgacttccaaaactttttgagaacccagactggaaat acaactacagtcaacataatcataagcacagtggactatcttctgagactgcaggagtcc atcagtgacttctattggtattattctggaaaggatgtgatggatgaggccggccagcgt aatttctctaaagctttggccgtggccaagcagatcttcaactctcttacagaatatatt cagggtccatgtataggaaatcagcagagtttggcccacagcagattatgggatgcggtt gttggctttctgcatgtgtttgctaacatgcagatgaagctttctcaggactccagtcag attgaattgctgaaggagttgatggatctacaaaaggacatggttgtcatgatgctctcc cttctagaaggtaatgttgtaaatggtaccattggtaaacaaatggttgacaccttggtg gagtcctcaagtaatgtggagatgattctcaagtttttcgacatgttcctcaagctgaaa gacctcaccacttctgacagttttaaggagcatgactctgatggcaaaggaataatttct aaaagagaattccagaaatctatggagaaccagaagcagtactctcagtccgagatagaa ttcttactttcctgtgttgaggcagatgaaaatgacctgttcaactatgttgagtttgta aaacgcttccatgaacctgccaaggacattgggtttaacgttgctgtgctgctcaccaat ctgtcagaacacatgcctcatgattcccgcctggccacctttctgaacctggctgagagt gtccttaattattttgaaccctttctaggtcgtattgaaatcatgggtggggccaagaga atcgaacgggtctactttgatatcagtgagtctagcagaacccagtgggaaaagcctcaa gtaaaggaatccaagagacagtttatctttgatgtggtgaatgagggtggagaatcagag aagatggaactctttgtgaacttctgtgaagacaccatctttgagatgcagctggcatct ctgatctctgaaccagatgctgtggaaaggaaagaaggagatgagaatttgcacagtgta acccatgagcctgaggaagaacatgaagatgtcatgctggaatcttcttcagcttttacg atggcctgcgtctccatgagaaaaaacttctgcacccttggcaagttgcttactctgaaa agcttaaaaaagcagtacaagaagcttaggaagatgagtctgagagagatgatctgtgga ttcctcacttttttctggacaatcttttttggcatattccgcttcctttataacttggtt tggggtttcttccacattctctggtccaccatgtttggaggaggcttggtggaaggtgcc aaaaatatgaaggtgacagacattctgggtaacatgccagaccccacacagtttggcatc catggtgatgttctagagactgataaactggaggtgaatgagacttctttagtggctgag attggccagcttgcagaggcagacaatgaagaaatggacctcatgtcagaactgctgagt atccagcccaagaaagagggaggaaagcatggtactgagcctggtcttggagatttgtct gaagtggctggagtggattctccatcatcattagctgctgctgtacgtcagaaaaaggcc caggaagctgcaactaaatccactgagactgagacaaaatcagaaacagaaaaagcagac actgagtatggggagaaaagggacaaagacaaagctacagaatcacccacaaaaaggaca tcagataaaaagaggaagccaccaaagagaagatgtgggctgaagaaggaaccaccagaa gccattatggccagtttttttgctggcctggacatttatcagacaaagattttgaattac ttggctcgaaacttctacaatctgcgatttctggctctgtttgttgcatttgccatcaac ttcattctgcttttctataaggtgattactattgttcttttaaatgtgcaaaattgtcct tacttttcatattctgaggaagtggattcatggacaggaagaggtgatgaggaggaagtt gggattgagtactttgtcctacaggagaacactggttacatggcacctacgctgcgcttt ctagctgtattacacactatcatttcctttctctgcgttgtgggatattactatctaaag gtgcccttagtggtgtttaagcgagaaaaggaaattgccaggaagcttgagttcgatggt ctttatattactgaacaaccttcagatgatgacatcaaaggacaatgggacagacttgta attaacacaccatcgtttccaaataactactgggataagtttgtaaaacgcaaggtaata aataaatatggagacttgtatggcgcggaacggattgccgagttgcttggtctggacaag agcgctctggacttcaacccgactgaagagaccattgctaaagaagcctcgctggtaacc tggttaagttccattgacaccaaatatcatatctggaaaatgggtgtggtgtttacagac aattcttttctctacctggtatggtatactactatgtccatcctgggtcactacaacaac tttttctttgctgctcacctgctggacattgctatgggttttaagaccctaaggaccatc ctgtcttcggttacccacaatggcaaacagttagtgctgactgtaggtctactggctgtg gttgtgtatctatacaccgtggtggcctttaacttcttccgcaaattctataacaagagt gagaatgaggacgagccagatatgaagtgtgatgacatgatgacatgctaccttttccac atgtatgtgggtgtacgtgctggtggtggaataggggatgagattgaggacccagcaggt gacccctacgagctttaccgcatcctctttgacatcaccttcttcttcttcgtcattgtc atccttctggcaattattcagggtttgattattgatgcttttggagagctgagagaccag caggaacaagtgaaagaggacatggagaccaaatgttttatctgtggaattgggaatgaa tactttgacaccactccacatggctttgagacacacactttacaagagcacaacttggcc aactacctgttcttcctgatgtatctcattaacaaggatgaaacagagcacacaggccag gagtcatatgtgtggaaaatgtatcaggaacgatgctgggatttcttcccagctggagac tgtttccggaaacagtatgaagaccagctaaattag

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