Takifugu rubripes (torafugu): 101061364 Help Entry 101061364         CDS       T02386                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X14   KO K04963   ryanodine receptor 3 Organism tru  Takifugu rubripes (torafugu) Pathway tru04020   Calcium signaling pathway tru04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:tru00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101061364 (ryr3)    04020 Calcium signaling pathway     101061364 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:tru04040]     101061364 (ryr3) Ion channels [BR:tru04040]  Voltage-gated cation channels   Ryanodine receptor    101061364 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 Motif Other DBs NCBI-GeneID:  101061364 NCBI-ProteinID:  XP_011610427 LinkDB All DBs Position 16:complement(9850050..9907143) Genome browser AA seq 4864 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVATIQKEHRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLANTGQSSEGAGQGGGHRTLLYGHAILLRHSFSDMYLTC LKTSRSLTDKLSFDVGLQEHSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSTERYL HLSISNGSTQVDASFMQTLWNIQPTCSSGNMAVGYLIGGHVMRLCHGHDESLTIPGAESS EEMQRIVNYEAGKGASKARSLWRLEPLRISWSSSHIRWGQAFRLRHLSTGRYLALSEDRG LVLQDREKSDTTATAFCFRPSKEKSDLGAKRDIDGMGVPEIKYGDTVCFIMHVATGLWLS YLAPDAKSSRLGPLKRRACLHLEGHMDDGLILQRCQHEESRAARIIRNTTFLFTNFIRAL DRITKGGSTEVAGFVEDVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQDLFKEEGM LTLLSKCIDRMNLYNSAAHFAEKAGEEAGAAWKDILNLLYELLAALIRGNRTNCTQFSHK LDWLVSKLERLESSSGILEVLHCILVESPEALNIIQRAHIESIISLLYKHGRNHKILDVL CSLCVCNGVAVRANQNLICDTLLPERDLLLQTRLVNDVQSMRPNIFLGVADGSAQYKKWY FELVIDQVDHFVTGESTHLRVGWANTRGYAPYPGGGEGWGGNGVGDDLYSYSFDGLHLWS GRIPRAVASVNQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGFFFPVVSF SAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHIEAVKDYKRDHEGVRDLLGTT QFLSQSSFIPTPVDTSQVVLPTHLDNVRDKLAENIHELWGMNKIELGWTYGKIRDDNKRQ HPCLVDFVKLPETERNYNLQMSSETLKTLLALGCHVAQVNIHAEDDLKKIKLPKDYMMSN GYKPAPLDLSDVKLTGGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDVKSRRNPRLVP YALLDERTKKSNRDSLREAIRTLVGYGYDIDPPDQEGAHVVVDETIETTRLFRVEQTYAV KTGKWYFEFEAITGGDMRVGWARPGCRPDVELGADDQVFVFDGYRGRRMHAGSRYFGHPW KKGDVVGCMINMEDKSMIFTLNGELLITNKGSELCFTDFETEEGFIPVCSLGMSQIGRMN LGKDASTFKYYTMCGLQEGFEPFAVNMKREITMWFSKRLPTFVNIQQDHAHIEVTRIDGT VDSPPCLKVTHKTFGTQNSNSDMLYCRLSVPVEFYSADTLLDESLRFSYPPNDDGSADYG SITMYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFNLGKTRTVTVTLGDERGRVHESVQ RSNCYMVCAGDAVSPSSSSRSTSDLEIGCLIDLATGLVTFTANGKELSTVYQVEPNTKLF PAVFVRPTSADLFQFEFVKMKDAMPLSSAIFKSEHRNPVPQCPPRLDVQTIVSVLWSRMP NTFLNVETARVSERHGWVVQCLEPLQIMAVHIPEENRCLDILELSEHEDLRKFHYHTLML YCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYSVLISIHLETAKEARLM MNNEFIIPVTDETRSIKLFPDESKRHSLPGVDLSTSLKPRVNFSPVGVINRGRHQYLHSP QIPLGILKEKAISMLTEAVQGGGTHIRDPVGGSVKYQFVPILKLIGTLLIMGVLTSEEVR VILLMIDPNVFGEVQEGEEARGEEAGPAAEKEEVSKNEEKAVEAGEEESKPSATKGLLEK LLPEPVKRQMCELLQYFCDCELKHRIESIVSFSDTFVSKLQFNQKFRYNELMVALNMSAA VTAKKTKEFRSPPQEQINILLNFSAGDDCPCPEEIQEELNSFHEELRLHCGIPIEEEEED QDTSIKGRLLALLYKIKGPPQKAEKEPEKEQAAPTNLKELISQTITCWAQESHIQDPELV RVMFSLLRRQYDGIGELLRGMKKTYTISAASVQDAINLLASLGQIRSLLSVRMGKEEEKL MIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPKMVASCCRFLC YFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGLALALEEPD LEKVVTYLAGCGLQSCAMLLAKGYPDLGWNPIEGERYLSFLRFAVFCNGESVEENANVVV KLLIRRPECFGPALRGEGGQGLLVAMKEAIKISEDPSLDLPKIPDGVSAGPGEEGGEIIH MGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTLDLVGIISIPPKMP MVNKDGSVTEPDMSACFCPDHKAPMVLFLERVYGIQDQTFLMHMLEVGFLPDLRASASLD TEALSTTETALALNRYIGSAVLPLLTRCAALFAGTEHYTQLIDSTLQTIYRLCKGRSLTK AQRDAIEECLLAICKHLRPTMMQQLLRRLVFDVPVLSEYCKIPLRLLTNHYEQNWKYYCL PAGMGSFGTASDEELLLTKKLFWGTFDSLSHKKYDPELFKMATACLCAIAGALPPDFVDA SLGATLEKQASLDSQGNFDPKPINTANISLPEKLEYITNKYAEHSHDKWSSEKVSAGWKH GESLDEHTKSHPLLKPYKALTEKERETYRWPVRESLKSMLAMGWNIERSKEGEPMFQREG DTHKKTSDPQINGFSPAPMDLHNITLSRELQSMVEMVAENYHNIWAKKKKTELISKGGGT HPLLVPYDTLTAKEKYRDREKAQELFKFLQISGYIVSRGLKDIEQDSSSMEKRFSYKFLK RLLQYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLTDQTFKNHCLYFLSTP SKNLSSCGCASNKEKEMVTSLFCKLAALVRHRISLFGSDSTIMVSCLDILTHSLDTRTVM KSGSELVKAGFRTFFENAAEDLEKLVEMLKLGKFMQSRAQMKSVSQSINYVTVALLPILT ALFDHIKTHEFGIDLLLNDVQLSCYRILTFFYSLGTGKNIFVERHLPALGESLATLVGAM PVAFLEPDLNAYNPLSVFNTKTPRERAILSMPDTVEEMCPEIPRLDKLLKDVNDVSESGA RYSDMPQVIEVILPMLCNYLSYWWEKGPENSPPDAQCCTMVTSEHLSVILGNILRILNSN LGIDDAPWMKRIAVYSQPIICKAGAGLLRSHFLPTLVKLKKKTEKVVAEEELLKADSKGD NQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKEPDADSTELFRMVAEIFILWC KSHNFKREEQNFVVQNEINNLGFLTGEAKTKMSKSGGDQERKHKRRRGEYYSIPTSLIVA ALKKMLPIGLNMCTPGDQELISVAKKRYSLKDTDDEVKEHLRQNLHLQDKSDDPAVQWQL NLYRDVVVKCEEPVNPEHTVSRVQSISAALFHLDLVEQPLRNKKCVWQKLLSKQRKRAVV ACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPMKIVEEEEEEVA EIQPDPLHQLILHFSHNALTERSHLEEDPLYIAYADMMAKSCAEDEEEEEEEEKEKTFEE KEMEKQKILYQQARLHARGAAEMVLQMISATKGRLGPMVTCTLKLGISILNGGNVQVQQK MLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSIHTQRGSKVLQ NDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWY YSGKDVIDDTGKLNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVF ANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSNNVE MILKFFDMFLKLKDLTTSDNFREYDPECKGIISKKEFQKSMESQKQYSQSEIEFLLSCAE ADENDMFNYKEFVERFHEPAKDIGFNVVVLLTNLSEHMPHDSRLATFLDLAESVLSYFEP YLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGGESEKMEMFVN FCEDTIFEMQLASKISEPDVGEQPEEEEDDGHSILGDLVGEEDDALESASAFSAACRSVK RRISKVRHLFSIKNVRKQFKKIKKLSIKEIITGFFSFFWMLFTGFFRGIYSIIFGFFHII WASMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVIEGEKVEALESSGSLDITMTPAG DTAEVDVMLELLTSPKKEGGKHMEPGLGDMSELSSETAATDQKKVRKQRRLFGKPVFPSL TSFHPSGGQKAMKTEETPESEPEKADTENREKEDKPTEKETKETVTEEKPKARSSRQKDE APAFTSSVFALLDVYLTKLLNYLARNFYNLRFLALFVCFAINFILLFYKVAGDDTDDENR WGGDAEDDEDTFFDMDEFVLQESTGYMLPTLRFLAVFHTIISLLCLVGYYCLKVPVVVFK REKEIARQIEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDLY GAERIAELLGLDKSALDFDPTVETVEKEASLVSWLSSIDTKYHTWKLGVVLTDNNFLYLI WYTTMSIFGHFNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTV VAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYR ILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPH GFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPTGDCFRKQYE DQLG NT seq 14595 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggcggagaaggagaagatgagatccagttcctgagaactgatgatgaagtg gtgctccagtgtgtggccaccatccagaaggagcatcggaagttctgcctggccgctgag ggactgggcaaccgtctgtgctacctggagcccacctctgaagcgaagtatgttcctcca gacctgtgcatctgcaactttgtgctggagcaatccctgtcggtccgggccctgcaggag atgctggccaacactgggcagagcagcgaaggggccggtcaggggggtggacaccggacc cttctctatggtcatgccatcctccttcgccactccttcagtgacatgtatctgacctgt ttgaagacatcacgctccctgacagacaagctgtcgttcgacgtcggtctgcaagaacat tcaacaggagaggcctgctggtggacgatccacccggcgtccaagcagaggtcagaggga gagaaggtgcgcatcggagacgacctgattctcgtcagcgtgtccacagaacgatacctg cacctgtccatctccaacggcagcacccaggtggacgcctctttcatgcagaccttgtgg aacattcagcccacctgctcgtcgggcaacatggctgtaggctacctgatcggcggacac gtgatgcgtctctgtcacggccacgacgagagcttgaccatcccgggagcggagagcagc gaggagatgcagaggatcgtcaactacgaggcgggtaaaggggcatcaaaggctcgttct ctctggaggctggaacctttgaggatcagctggagcagcagccacattcgctggggccag gccttccggctgcgtcacctctccaccggtcgctacctggctctgagcgaggaccgagga ctggtcctgcaggaccgggagaagtctgacaccacggccaccgccttctgcttccggccc tccaaggaaaaaagcgacctgggtgcaaagagggacatcgatggaatgggggtgccagag atcaagtatggcgacacggtctgcttcatcatgcacgtggctacaggactctggctgtcc tacctggcgcccgatgccaaatcatcacgcctggggcccctgaagagaagggcctgcctg catttggagggtcacatggatgacggcctcatcctgcagcgctgccagcacgaggagtcg cgcgctgctcggatcatccgcaacaccaccttcctcttcaccaacttcatcagagctctg gatcgcatcaccaaggggggttccacggaggtcgccggtttcgttgaggatgtgctgcag acgctgaatgacctgatcgaatacttcaagcagccggactcagagctggagcacgaggag aaacagtgtctcctgcgctcgctcatcaaacgtcaggacctcttcaaggaggagggcatg ctgaccctgctgtccaagtgcatcgaccggatgaacctgtacaacagtgctgcccacttt gcagagaaggccggcgaggaggctggagcggcgtggaaggacattctgaacctcctctat gaactgttggctgctctgatacgtggaaacagaaccaactgcactcagttttcccacaag ttggactggctggtcagcaaactggagagactggagtcttcatcagggatcttggaggtc cttcactgcatcttggtagagagtcccgaggctctcaacatcattcagagagcccacatc gaatccatcatctctctgctctacaagcatggacgcaaccacaagattctagatgttctg tgttccctctgtgtttgtaacggggtggcagtgagagccaatcagaatctgatctgtgac acgctgcttcctgagagggacctactgctgcagactcgactggtcaatgacgtccagagc atgaggccaaacatcttcctgggtgtggccgacggctccgcccagtataagaagtggtat ttcgagctggtgatcgaccaggtggaccactttgtcactggggagtccacccacctgagg gtaggctgggccaacaccagaggctatgctccctaccctggtggcggagagggttggggt ggcaacggtgttggggatgacctctactcctacagctttgatggacttcatctgtggtca ggtcgaatcccaagggccgtggcctccgttaatcagcacctgctgaactcggacgatgtg gtcagctgctgtctggatctgggcgcgcccagcatgtccttcaggatcaacgggcagcct gttcagggcatgttcgaggacttcaacacagacggcttcttctttcctgttgtcagcttc tctgcaggtgttaaggttcggttcttgttgggtggacgacatggagattttaagttcctg cccccagctggttattctccctgctatgaggcgttgctgcccaaagaaaagatgcacatc gaggctgtgaaagactacaagagggaccacgagggggtgcgtgacctgctgggaaccacc cagttcctctctcagtcctcctttatcccaacacctgtggacaccagtcaggttgtcctt cctactcaccttgacaacgtgcgggacaagctggcggaaaacatccacgaactgtggggc atgaacaagattgaactaggctggacatacggcaagatccgcgatgacaacaagaggcag cacccgtgcctggtggattttgtcaagctgcctgaaactgagaggaactacaacctgcag atgtccagtgaaactctgaagaccttgctcgctctcgggtgccacgtcgctcaggtcaac attcacgctgaagatgacctgaagaaaatcaaacttcccaaagactacatgatgtctaat ggatataagcctgcgccactggacctctctgacgtgaaactgactggaggtcaggaggtt ctagttgataaactggccgagaacgcgcacaacgtgtgggccaaagacagaatcaaacaa ggctggacctacggcatccagcaggatgtgaagagcaggcggaatcctcgcctggtgccg tatgcgttattagacgagcgcactaaaaagtctaatagagacagtttgagagaggccatc aggactctggttggctacggatatgacattgaccccccggatcaggagggtgctcatgtg gtggttgatgagaccatcgagaccacccgcctgttccgcgtggagcagacgtacgcagtg aagacggggaaatggtactttgagtttgaggccatcacgggcggcgacatgagggtcggc tgggcccgaccgggctgcaggcccgacgttgaactgggagcagatgaccaggttttcgtc ttcgatggttacaggggccggcgcatgcacgcaggaagccgctacttcggacacccgtgg aaaaagggcgacgtggtcggttgcatgatcaacatggaggacaagtccatgattttcacc ctgaacggagagctcctcatcaccaacaagggctcagagctctgcttcactgactttgag acagaagagggtttcatccctgtctgcagcctgggtatgtcccaaatcggacgtatgaac cttggaaaggatgccagtacctttaagtactacaccatgtgcggtctccaggaagggttc gagcccttcgccgtcaacatgaagcgagagatcaccatgtggttcagcaagcgcctcccc acctttgtcaacatccaacaggaccacgctcacatagaggtgacgcggatcgacggaacc gtggacagcccgccctgcctcaaggtcacccacaagacattcggtacccagaacagcaac agcgacatgctgtactgtcggctgagcgtgcccgtggagttttactccgcagacacgctt ctggacgaatcgctccgattcagttaccctcccaacgacgacggaagcgctgactacgga agcatcaccatgtactaccactcggtgagagtgtttgccggacaggaccctgcgtccgtg tgggtgggctgggtcacgcctgactaccactactacagcaagaactttaacctcggcaag acgaggaccgtcaccgttaccctgggagacgagagaggccgcgtccacgagagtgtccag aggagcaactgttacatggtgtgtgcgggggacgccgtcagcccgtcttcctccagccgc tccacctctgacctggagatcggctgcctgatcgacctggccactggcctggtcaccttc accgctaacggcaaggagctgtccacagtgtaccaggtggagccgaacaccaagctgttc ccggctgtgtttgtacgaccgacctctgctgaccttttccagtttgagtttgtcaagatg aaggatgcgatgccgctctcatctgccatattcaagagcgagcacaggaatccggtcccc cagtgccccccgcgcctggacgtgcagaccatcgtttctgtcctgtggagccgcatgccc aacaccttcctcaacgtggagacggcgcgcgtcagcgagagacacggctgggtggtccag tgtctggagccgctgcagatcatggctgtgcacatccccgaggagaacaggtgtttggac atcctggagttgtccgaacacgaagacctgcgcaagttccactaccacaccctgatgctg tactgcgccctgtgtgcgctgggaaacacccgtgttgctcacgccctctgcagccatttg gaccagtcgcagctgctctacaccatcgacaaccagtacctgtctgggatgctgagagag ggcttctacagcgtcctcatcagcatccatcttgagacggcgaaggaggctcgcctgatg atgaacaacgagttcatcatccccgtgacggacgagacccgctccatcaagctcttcccc gatgagtccaagcgccactccctgcctggcgtggaccttagcacctccctgaagcctcgg gtcaacttctccccggtgggggtgatcaaccggggcaggcaccagtacctccacagtcca cagatcccactggggatcctaaaggagaaagccatcagcatgctcaccgaggccgtgcag ggtggaggcacgcacatccgagatccggtgggcgggagcgtgaagtaccagtttgtcccc atcctcaagcttattggaacgctcttgatcatgggggtcctcaccagcgaggaggtgaga gtaatcctcctcatgattgaccccaatgtgttcggagaggtccaggagggcgaggaggcg aggggggaggaggctggcccggccgcagagaaggaggaggtgagcaagaacgaggagaag gccgtggaggcgggagaggaggagagcaagccgtcggcgactaaaggtctcctggagaag ttgctcccagagcccgtcaagcgccagatgtgcgagctgctgcagtacttctgcgactgt gagctgaagcaccgcatcgagtccatcgtctccttctccgacaccttcgtctccaagctt cagttcaaccagaagttccgctacaacgagctgatggtggcgctcaacatgtcggccgcc gtcaccgccaagaagaccaaagaatttcgctctcccccgcaggagcagatcaacatcctg ttgaatttcagtgcaggagacgactgtccctgtcctgaggaaatccaggaggaactcaat tccttccacgaagagctgcgcctgcattgtggaatccccattgaggaggaagaggaagat caggacacttcgattaaaggccgccttctggctttgctctacaaaatcaaaggccctcct cagaaagcagaaaaggagccagagaaggaacaagctgcccccactaacctgaaggagctg atctcccagaccataacctgctgggctcaggagtctcacatccaggacccagagctggtc agggtgatgttcagcctgctgaggaggcagtatgacggaatcggagagctgctccggggc atgaagaaaacctacaccatcagcgccgcctctgtgcaggatgctatcaacctgttagca tctctggggcagatcaggtcgctgctgtccgtgcggatgggcaaagaggaggagaaactc atgatcgatgggctgggtgacattatgaacaacaaggttttctaccaacatcccaacctg atgagagtcctgggcatgcacgagaccgtcatggaggtcatggtcaacgtgctgggagga gacaagtcccaggagatcgccttcccaaagatggtggccagctgctgccgcttcttgtgc tacttctgtcgcatcagccgtcagaaccagaaagccatgtttgaccacctgagttacctg ctggagaacagcagcgttggccttgcctctgaagccatgcgaggctcgaccccgctcgac gttgcagcgtcttcagtgatggacaataacggcctggccctggctctggaagaacctgac ctggagaaggtggtcacatacctggcaggctgtggcctccagagctgcgccatgctgctt gctaagggttacccagacctgggctggaaccccatagagggagagcgctacctgtccttc ctgaggttcgccgtcttctgcaatggagagagcgtggaggaaaacgccaacgtggtcgtg aagctcctgatcagacgccccgagtgttttggtcctgctctcaggggagagggaggtcag ggtctgctggtggccatgaaggaagccatcaagatctcagaggatcccagcctagatcta cccaagatccccgatggagtcagtgctggtcctggcgaggaaggaggagaaatcattcac atgggcaacgccatcatgtctttctactcggctctgatcgacctgctgggacgctgcgcc ccagagatgcatctcatcaacgcaggtaaaggggaagcgctccgaattcgggccattctt cgctctctggttcctactctcgacctcgtgggaatcatcagcatccctccaaaaatgccc atggttaataaagatggctccgtgacggagcccgacatgtcggcctgtttctgcccggac cacaaggctcccatggtgctcttcctggagcgagtgtatggcattcaggaccagaccttt ctgatgcacatgctggaggtcggcttcctgcctgacctgcgggcatctgcctctctggat acggaagcactgagcaccaccgagaccgcgctggctctgaaccggtacatcggctcggct gtgctgcccctgctgacccgctgcgccgccctcttcgccggcaccgagcactacacacag ctgatcgactccactctgcagaccatctaccggctgtgcaaagggcgctcgctcaccaaa gcccagagggacgccatcgaggagtgcctgctggctatctgcaaacatctgcgccccacc atgatgcagcagctgctcaggcggctggtgttcgatgtccccgtgctgagtgaatactgc aagattcctctcaggcttctcaccaaccactacgagcagaactggaagtactactgtctc cccgccggcatgggcagctttggcaccgcctctgatgaagagctgctcctcaccaagaaa ctcttctggggaacctttgactctctgtctcacaagaagtatgaccccgagcttttcaaa atggccacggcatgcctgtgcgccatcgccggagccctcccccctgactttgtggacgcc agtctgggagcaacgctggagaaacaggcgtcgctggattcacagggcaactttgacccc aaacccatcaatactgccaatatctcccttcctgaaaaactggagtatatcaccaacaaa tatgcagagcattcccatgacaaatggtcctctgagaaggtgtcggcagggtggaaacac ggagagagcctggatgaacacaccaagtcgcatcctttgctgaagccttacaaagctctg actgagaaggagagggaaacgtaccgctggccagtgagggagtcactgaagagcatgttg gctatgggctggaacattgagaggagcaaagagggggaacccatgttccaacgagagggt gacacacacaagaagacctctgaccctcagattaacggattcagtcctgctccaatggac ttgcacaacatcacgttatctagagagctgcagagcatggtggaaatggttgcagaaaat taccacaacatctgggccaagaaaaagaagacggaactcattagcaaaggaggagggacc cacccgctgctggttccctatgacaccctgacagctaaagagaagtacagagacagagag aaggcccaggagctcttcaagtttctccagatcagtggctacatcgtcagcaggggtctg aaggacattgagcaggactcatcttccatggagaagcggttttcttacaagttcctcaaa aggctgctgcagtatgtcgactccgcccaggagttcatcgcacacctggaggccatggct acgagtggaaagacggacaaatcgccccatgaccaggaaatcaagttctttgccaaggtc ctgctccctctcacagaccagacgtttaaaaaccactgtctgtacttcctgtccacgccc agcaagaacctgagcagctgcggatgtgcttccaacaaagaaaaggagatggtgaccagc ctgttttgtaagctggcagctcttgtcaggcacaggatttctctctttggaagtgattcc accatcatggtgagctgcctggatattctcacccactctctggacaccaggaccgtcatg aagtccggatcggagctggtcaaagccgggttccggactttcttcgagaatgcggcggaa gacctggagaagctggtcgagatgctgaaactggggaaattcatgcagtcccgcgcacag atgaagagcgtcagtcagagcatcaactacgtgaccgtggcgctgctgcccatcctcacc gccctgttcgaccacatcaagacgcacgagttcggcatcgacctgctgttgaatgatgtt cagctttcctgctacagaatcttgacctttttctactctctgggaacaggaaagaacatc tttgtggagaggcatcttccagcactgggggagagtctggcaacactggtgggggccatg cctgtggccttcctcgagcccgacctaaatgcctacaacccactgtcggtcttcaacacc aaaaccccccgagagagagccattctcagcatgcctgacacagtggaggagatgtgtccg gagatccctcgcctggacaagctcctcaaagacgtcaacgatgtctcagagtccggagcg cgttacagtgacatgccacaggtcattgaggtgatcctccccatgctgtgtaactacctg tcctactggtgggaaaagggtccagagaactcccctccagacgcccagtgttgcaccatg gtgacctctgagcacctcagcgtcatcttgggcaacatcctcaggatcctcaacagcaac ctgggaatcgatgacgcaccctggatgaagaggattgcagtctactctcagccaatcatc tgcaaggctggagctggcctgttgaggagccatttccttcccacgctggtcaaactgaag aagaagacagagaaggttgtggctgaagaggagctgctgaaggcggacagtaaaggcgac aaccaggaagcagagctgctcatcctggatgagtttgctgtgctctgcagggacctctac gccttctaccccatgctcatccgctacgtggacaacaacaggtccaggtggctgaaggag ccagacgcagactccactgagctcttcaggatggtggcggaaatcttcatcctgtggtgc aagtcccacaatttcaagcgtgaggagcaaaactttgtggtgcagaatgagatcaacaat ttgggcttcctgactggagaggccaagacaaagatgtccaagtcaggtggcgaccaggag aggaagcacaagcggcgtcgaggcgagtactactccatccccacctctctgatcgtagct gctctgaagaagatgctgcccatcggcctcaacatgtgcactccaggagaccaggagctc atatctgtagccaagaaacgctacagtctcaaagacacggatgatgaggtgaaggagcac ttgcgtcagaaccttcacctccaggacaaatcagatgacccagcggtccagtggcagctg aacctttacagggacgttgtggtgaaatgtgaggaacctgtgaaccccgaacacacagtg agccgagtacagagcatctctgctgcactcttccacctggacctggtggaacagccgctg aggaataagaagtgcgtgtggcagaagctgctgtccaaacaaaggaaacgtgcggtggtc gcctgtttccgcatggctccgctctacaatctccccaggcatcgcgctatcaacttcttc atcccggcctatcagagactatggatagaggcagaggagtactcctttgaggagaagcta gttcaggatctggcaaaaacccccatgaaaatcgtggaggaggaggaagaggaggtggct gagatccagccagaccctctccatcaactcattcttcactttagccacaatgcgctgaca gaaagaagtcatttggaagaagatcccttgtatattgcatatgcagatatgatggcaaag agctgtgcagaggacgaggaggaagaagaggaagaagaaaaagaaaaaacgtttgaggaa aaagagatggaaaagcagaagatcctgtaccagcaggcgcggctgcacgcccgcggcgca gctgagatggtgctgcagatgatcagcgccactaaaggccgactgggccccatggtgacg tgcacccttaaacttggaatctcgatcttaaatggaggcaacgtgcaagttcagcagaaa atgcttgattacctgaaggagaagagagatgcgggattcttcaagagtctctcaggactg atgcagtcttgcagcgtcctggatctgaatgcatttgagaggcagaataaagcagaggga cttggaatggtgacagaggaaggttcaatccacactcagcggggttccaaggtgctacag aatgatgagttcacaaaagatctgttccggtttttgcaacttctttgcgagggtcacaac ggagatttccagaacttcctgagaacccaaactggaaacaccaccacggtgaacatcatc atcagcactgtggactacctgctgcgtcttcaggagtccatcagcgacttttactggtac tactctggtaaagacgtcatcgacgacacgggaaagctgaacttctccaaggctctatct gtcgccaagcagatattcaactcgctgacggagtacattcagggtccgtgcattgggaac cagcagagtctggctcacagcagactgtgggacgcagtggtgggcttcttgcatgttttt gccaacatgcagatgaagctgtctcaggacgccagtcagatcgagttgctgaaggaactg atggatttgcagaaggacatggtggtcatgttgctgtctctgcttgaaggtaatgtggtg aacggaacaattggaaagcaaatggtggacaccctggtggagtcctccaacaacgtggag atgatcctcaagttcttcgacatgttcctaaaactgaaggatttgaccacctcggacaac ttccgagagtacgaccccgagtgcaaaggtatcatttcaaagaaggagttccagaagtcg atggagagccagaagcagtacagccagtcggagatcgagttcctgctctcctgcgccgag gccgacgagaacgacatgttcaattacaaggagtttgtggaacggttccacgagccggcc aaagatatcggcttcaacgtggtggtgctgctaacaaacctgtcggagcacatgccgcac gactccagactggccaccttcttggacctggccgagagcgtcctcagctacttcgagcct tacctgggccgcattgaaatcatgggcagcgccaagcggatcgagagggtgtattttgag atcagcgagtcgagccgtgagcagtgggagaagccgcaggtcaaagagtccaagcggcag ttcatctttgacgttgtcaacgaaggcggcgaaagtgagaagatggagatgttcgtgaac ttctgtgaggacaccatttttgaaatgcagctggcctcaaagatctccgagcccgacgtc ggggagcagcccgaggaggaggaagatgatggacacagcatcctgggagacctggttgga gaggaagacgacgctctggagtcggcttcggccttcagcgccgcatgtcgatcggtgaag aggagaatctccaaagtgcggcatcttttctccattaaaaacgtccgcaagcagtttaag aagatcaagaagctgagcattaaggagatcatcactggcttcttctccttcttctggatg ctcttcaccgggttcttcaggggcatctacagcatcatatttggcttcttccacatcatc tgggcttccatgtttggcggcggcctggtcgaaggagccaagaacatgaaggtgacggac attctcggaaacatgcccgacccaacccagttcggtatccacggagatgtgatcgaagga gagaaagtggaggccctggagtcgtcggggagcctagacatcaccatgacaccagcaggc gacacagcagaggtggacgtgatgttggagctgctgacgtcacccaagaaggaaggaggg aaacacatggagccgggactgggcgacatgtccgagctgagctccgagaccgctgcgact gatcagaagaaggttcggaagcaaagacggttatttggaaaacctgtttttccctcatta acttcatttcatccttctggtggacagaaagcaatgaagacggaagaaactccagagagc gagccggaaaaagcagacaccgagaaccgcgagaaggaggacaagccaacggagaaggag acgaaggagacggtgacggaggagaagcccaaggccagatccagccgccagaaagacgag gctcctgcattcacgtccagcgtctttgctcttctggatgtctatctgaccaagctgctg aactatctggcccgaaacttctacaacttgcgtttcctggctctgtttgtgtgtttcgcc atcaacttcattcttctgttctacaaggtcgccggtgacgacacagatgatgaaaaccgc tggggcggcgacgctgaggacgacgaggacaccttcttcgacatggacgagtttgtcctg caggagagcaccggttacatgttacccaccctgcgcttcctggctgtgttccacaccatc atatcgctgctgtgcttggtcggctactactgtctgaaggtccctgtggtggtctttaag agggagaaggagatcgccagacagattgagtttgatggtctttatatcaccgaacagcca tctgatgatgacatcaagggccagtgggaccgactcgtcatcaataccccatcgttcccc aataactactgggacaagttcatcaagcgtaaggtgatcaacaagtacggcgatctgtac ggagcggaacgcatcgcagagctcctgggcctggacaagagcgctctggattttgatccc accgtggagacggtggagaaggaggcttcacttgtctcttggctgagctccatcgatacc aagtaccacacctggaaactcggcgtagttctgactgacaataactttctgtatctgatc tggtacaccaccatgtctatttttggacactttaacaactttttcttcgctgcccacctg ctggacatcgccatgggcttcaagaccctccgcaccatcctgtcctcagtcactcacaac ggcaaacagctggtgctgaccgtgggcctcctggccgtggtcgtctacctctacactgtg gtggcgttcaacttcttcaggaagttctacaacaaaagcgaggacgaggacgagcctgac atgaagtgcgatgacatgatgacctgctatttgttccacatgtacgtgggcgtgagagct ggaggtggaatcggagacgagttggaggacccggcaggagacccctatgagctctatcgc atcctcttcgacatcactttcttcttcttcgtcatcgtcatcctgctggccatcattcag ggtttgatcatcgacgcgttcggcgagctgagggaccagcaggagcaggtgaaggaggac atggagactaaatgtttcatctgcggcatcgggaatgactactttgaccggacgcctcac gggtttgaaacccacaccctgcaggagcacaacctggccaactacctgttcttcctgatg tacctgatcaacaaggatgagacggagcacacgggtcaggagtcgtacgtgtggaagatg taccaggagaggtgctgggacttcttccccaccggagactgtttcaggaagcaatacgag gaccagctgggttaa

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