KEGG   Thermus thermophilus HB8: TTHA0075
Entry
TTHA0075          CDS       T00220                                 
Symbol
TTHA0075
Name
(GenBank) ribonucleoside-diphosphate reductase
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
ttj  Thermus thermophilus HB8
Pathway
ttj00230  Purine metabolism
ttj00240  Pyrimidine metabolism
ttj01100  Metabolic pathways
ttj01232  Nucleotide metabolism
Module
ttj_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
Brite
KEGG Orthology (KO) [BR:ttj00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    TTHA0075 (TTHA0075)
   00240 Pyrimidine metabolism
    TTHA0075 (TTHA0075)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ttj03400]
    TTHA0075 (TTHA0075)
Enzymes [BR:ttj01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     TTHA0075 (TTHA0075)
DNA repair and recombination proteins [BR:ttj03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    TTHA0075 (TTHA0075)
SSDB
Motif
Pfam: Ribonuc_red_lgC LAGLIDADG_3 Intein_splicing TSCPD Ribonuc_red_lgN Hint_2 LAGLIDADG_WhiA RNR-II_ins_dom LAGLIDADG_2 DrmE_C Zn_ribbon_IS1595
Other DBs
NCBI-ProteinID: BAD69898
UniProt: Q5SM68
LinkDB
Position
1:71430..78038
AA seq 2202 aa
MDMRDGYFFDEHAQAIARRQYLQPGDGDILGMFRRVAREIAKAEREEERSKWEEEFFRLM
AEKRFSPGGRILAGAGTVHGNLLNCFVQGATENPPESFAGIMEVAKKLALVTKVGGGNGV
NLDPYRSKGKRARRAVEGVAYLSAEHPDVEDFIRGLMRPPINPDGAKEEISLKNFARVVY
GALSPELKALAERYGVRTVKEPPEGRILVPDDMGGIIDAAREAADLARKGQKPHVDFSLL
RPEGAPIRGSGGTSSGPVSFLFEIFDNFLEWVAWGAEEAGPVATLRYVYAPVLRVVRQGG
CLHPDTLVHTDRGTLRLRELVDPFRRGWQPHTLSVATDEGWRPSPEGYNNGVAPTLRVVL
ENGLEVQGTLNHKLKVLREDGTREWVELQDLRPGDWVIWVLDEHTGTPVQLAPLDEPLHP
NTTPIRTPEVLTEDLAFLLGFFFGEGFVSGDRIGFSVHEEEPMREEAKRLFRELFGLELR
EERKPGDRSVTLVVRSRPLVTWLRKNGLLKGKARELEVPRAIRQSPRPVLAAFLRGLFEA
DGTITAGYPMLTTASKRLAQDVMVLLGGLGIPSKLLRYNPLPGRFSKAEHYRVRVVTAKG
LERYLERIGVPKGSRLEALHGIKPDIRRESSWPLPHAEGLLKPLLTVTEKGRKGYASPYT
PLRKDLLRYLRGERQLTATGYAMVLEKAQDLGLEAEPFPFNEYYVRVASVEPGGEILTLD
LSVEGNHTYLANGLVSHNTRRGAGMATLSIEHPDLLDFLTAKDLDREKAEGDISTFNISV
LATDRFLEAVEKDELWPVTPIEVPGKYYPYPVEGPYTGKLPPLPEREDGAKAIPLYGGKV
PARWLWHEIAWHAWATGEPGLIFVDRVNALSALKGLGERYQIRSTNPCFVGSTRIPTERG
LVPIEELAREGGSFYLVTDNRAPFGGRGAPLPGHGTAVRKAVRAFFTGVKPVVRLRTREG
LEVTLTPDHLLLTPEGYREAGKLRPGEKILVQSGEGLFPKEESLPAQALAVVHERVATAG
GRGGRGRADVRAQYRNLPTRWSRELGVALGWLLGDGYLREDGVGFYFSRKDFADLAWLPD
LLRDWFGQGTLQETRSDTFHLHFNRIPAEFFQALGLKAARATEKRVPESLFRAPREAVVG
FLQGLFSADGSVQINEKKQDATIRLASSSLALLQDVQLLLLNLGILGKIHKRREAARKAL
PDGKGALREYPVAPQYELILGGENRDRFAEVVGFLQEEKQSKLLAFLRHRPRGSYRKPFL
ATVASVEPAGEAPVYDLTEPVTHSLIANGLVAHNCGEIPLTVGEPCDLGAMNLAAYVKDG
EFQMEEFRRDVRTAIRFLDNVLDVNKFALPDNEMAAKKLRRLGLGLMGLADALIKMGLPY
DSEEARRKVYEIVSAMREEAIRASEALAEERGPFPLYEEHREYFQSLGIKPRRNVALLTV
APTGTTSMLMGVSSGIEPVFSPFVWRRIGGEYKPLLHPLFVELMEAYPPAPGFAKEGKWD
WEKIVEEIQKDGHGSVQNLPFVPEAIRRVFLSAHDIHPLDHVRMQGAVQRAFDAEGYAAN
SISKCIAKGTLIPTSKGLIPIEEIAPPHPEDTFVPVEGLYTAEGYRITAHYYAGKKRGVR
IRLDNGAELVGAWESHRLLTPEGWRLMRELKPGDVVLGKLVPSHGEGGLPIPEAKGLSLR
TNARNLPLPERMSEDLALFLGMLAADGSTVEATGFVGIATKDPDVERVFQEVAGRLFGVE
PKCTVDKRTGVRNLYLTSRRLVRFVEALIGKGAAQKRVPSQILQGSPGEKLAFLRGLTLD
GYVHANMGLVVYEGRSQRLAYEAAELARSFGLPKVYQGRKKVLAPKETYYVHSVAVSGPL
QELLEPLEAHKRAKVEARYKVFVPQEVLAATRVGTHHPGYVSLKSVRQREAQAVYNTTAE
RLGWPTEILAHRVVEVEEVGEVEMYDIEVEEVHRYVVNGLISHNTINLPNHATVEDVEAA
YTEAYRTGCKGITVYRDGSREFQVLTVKKEAKEEKAGKTPEEAKPQEARAHEPGRPVYER
PGRLMGFTDMVKLFAPDGSKRSFLVTVNTLEGRPIEVILTSGKAGDEANADSEALGRVVS
IALQYGVPPEAIVRTLRGINGGLYGTYQGRLVSSKADLIAVALETVPQMAPGAPEDLSSA
PVLSGGGIALAGAAPCPSCGEKALVREEGCWKCQACGYAKCG
NT seq 6609 nt   +upstreamnt  +downstreamnt
atggatatgagggacgggtatttctttgacgagcacgcgcaggccatcgccaggcgccag
tacctccagcccggggacggggacatcctgggcatgttccgccgcgtggcccgggagatc
gccaaggcggagcgggaggaggagcgctccaagtgggaggaggagttcttccgcctgatg
gccgagaagcgcttctcccccggggggcggatcctcgccggggcgggcaccgtccacggc
aacctcctcaactgcttcgtccagggcgccacggaaaacccccccgagagcttcgcgggc
atcatggaggtggccaagaagctcgccctggtcaccaaggtgggcgggggcaacggggtg
aacctggacccctaccgctccaaagggaagagggcacggcgggccgtggagggcgtggcc
tacctctcggcggaacaccccgacgtggaggacttcatccggggcctgatgcgcccgccc
atcaaccccgacggggccaaggaggagatctccctcaagaacttcgcccgggtggtctac
ggcgccctctccccggagcttaaggccctggcggagcgctacggggtgcggacggtcaag
gagcccccggaagggcgcatcctcgttcccgacgacatgggggggatcattgacgccgcc
cgggaggccgcggacctggcgcgcaaaggccagaagccccacgtggacttctccctcctc
cgccccgaaggcgcccccatccggggaagcggcgggacgagctcggggccggtgagcttc
ctctttgaaatctttgacaacttcctggagtgggtggcctggggggccgaggaggcgggc
cccgtggccaccctgcgctacgtctacgcccccgtgctccgggtggtcaggcagggaggg
tgcctccatcccgacaccctggtccacaccgaccggggcaccttgcgcctccgggagctg
gtggaccccttccggcggggctggcaaccccacactttaagcgtggccaccgatgagggc
tggcggccgagccccgaaggctacaacaacggcgtggcgcccaccctccgggtggtgctg
gaaaacggcctcgaggtccaaggaaccctcaaccacaagctcaaggtccttcgggaggac
ggaacgcgggaatgggtggaactccaagacctcaggcccggagactgggtgatctgggtg
ctggacgagcacacgggaaccccggtccagcttgcccccctggacgaacccctccacccc
aacaccacccccatccgcaccccggaggtgctcaccgaggacctggccttcctcctaggg
ttcttcttcggagagggcttcgtgagtggagaccggatcggcttctccgtccacgaggag
gagcccatgcgggaagaggccaagcgcctcttccgggagctctttgggctggagctccgg
gaggaacgaaagcccggcgaccggagcgtcaccctggtggtccggagccgtcccctggtc
acctggctcaggaagaacggccttctcaagggaaaggcccgggagctggaggtccccagg
gccatccgccaaagcccccgccctgtcctcgccgccttcctccggggcctctttgaggcc
gatggcaccattaccgcaggctaccctatgctgaccaccgcctccaaacgcctggcccag
gacgtgatggtcctcctgggggggcttggcatcccctccaagctcctccgctataacccc
ctgccggggcgcttctccaaggccgagcactaccgggtccgggtggtaaccgccaagggc
ctggagcgctacttggagaggatcggggtacccaagggctcccgcctagaggcccttcac
gggatcaagcccgacatccgccgggagtccagctggcccctgccccatgccgaggggttg
ctgaaacccctcctgacggtgacggaaaagggcaggaagggctacgcctccccctatacc
cccttgcggaaagacctcctccggtacctccggggcgagcgccagctcaccgccacgggg
tacgccatggtcctggaaaaggcccaggacctgggcttggaagccgaacccttccccttc
aacgagtactatgtgcgggtggcttccgtggagccggggggcgagatcctcaccctagac
ctttccgtggagggcaaccacacttacctggccaacggcctggtaagccacaacacccgc
cgcggggccgggatggccaccctctccatagaacaccccgacctcctggacttcctcacc
gccaaggacctggaccgggagaaggcggagggcgacatctccaccttcaacatctccgtc
ctggccaccgaccgcttcctggaggcggtggaaaaggacgagctctggcccgtgaccccc
attgaggtccccgggaagtactacccctatcccgtagagggcccctacacgggcaagctt
cctcccctccccgagcgggaggacggggccaaggccatccccctctacggggggaaggtc
cccgcccgctggctctggcacgagatcgcctggcacgcctgggccacgggggagccgggg
ctcatcttcgtggaccgggtgaacgcgctctcggccctgaagggcttaggggagcgctac
caaatccgctccaccaacccctgcttcgtggggtccacgcgcatccccaccgaacggggg
cttgtgcccattgaggagctcgcgcgcgaaggggggagcttctacctggtcacggacaac
cgggccccctttgggggcaggggcgcccccttacccggccacggcaccgcggtacggaaa
gcggtccgggccttcttcaccggcgtcaagcccgtggttcgcctccgcacccgggagggc
ctcgaggtgaccctcaccccggaccacctcctcctgaccccggagggctaccgggaagcg
gggaagctcaggccgggcgagaagatcctggtgcaaagcggcgagggactcttccccaag
gaggagagcctgcccgcccaagccctcgccgtggtccacgagcgggtggccaccgcggga
ggccggggaggccgaggccgggccgatgtgcgcgcccagtaccgcaacctccctacccgc
tggagccgggagctcggggtggccttgggctggctcttgggggacggctacctgcgggag
gacggggtgggcttctacttctcccggaaggacttcgccgacctcgcctggcttcccgac
ctcctccgggactggttcggccagggcaccctccaggaaacccgctccgacaccttccac
ctccacttcaaccgcatccccgcggagttcttccaggccctggggctcaaggcggccagg
gccacggaaaagcgggttccggaaagcctcttccgcgctccccgagaagcggtggtgggc
ttcctccagggcctcttcagcgccgacggctcggtgcagatcaacgagaagaaacaggac
gccaccatccgcctggcctcctccagcctggccctcctccaggacgtccagctcctcctc
cttaacctggggattctcggaaagatccacaagcgtagggaggcagcccgtaaggccttg
ccggacggcaaaggcgccctcagggagtacccggtggcgccccagtacgagctcatcctg
ggaggggaaaaccgggaccggttcgccgaggtcgtgggcttccttcaggaggagaagcag
tccaagctcttggccttcctgcgccacaggccccggggcagctaccgcaagcccttcctg
gccacggtggccagcgtggagcccgccggggaagcccccgtctacgacctgaccgagccc
gtcacccacagcttgattgccaacgggctcgtagcccacaactgcggcgaaatccccctc
accgtgggcgagccctgcgacctcggggccatgaacctcgccgcctacgtgaaggacggg
gagttccaaatggaggagttccgccgggacgtccgcaccgccatccgcttcctggacaac
gtcctggacgtgaacaagttcgccctccccgacaacgaaatggcggccaagaagctccgc
cgcctgggcctcggcctcatgggcctcgccgacgccctcatcaagatgggcctcccctac
gactcggaggaggcccggaggaaggtctacgagatcgtctccgccatgcgggaggaggcc
atccgggcctccgaggccctggccgaggaacggggccccttccccctctacgaggagcac
agggagtacttccagagcctcgggattaagccccggcgcaacgtggccctcctcaccgtg
gcccccacggggaccacgagcatgctcatgggggtctcctcggggattgagcccgtcttc
agccccttcgtctggcgcaggatcggcggggagtacaagcccctcctccaccccctcttc
gtggagctcatggaggcctacccgcccgcgcccggtttcgcgaaggagggaaagtgggac
tgggagaagatcgtggaggagatccagaaggacggccacggctccgtgcagaacctcccc
ttcgtccccgaggcgatccggcgggtcttcctctctgcccacgacattcaccccttggac
cacgtgcgcatgcagggggcggtccagcgggcctttgacgccgaagggtacgccgccaac
tccatctccaagtgcatcgccaagggcaccttaatccccacctccaagggcctcatcccc
attgaagagatcgccccaccccatcccgaggacaccttcgtcccggtggaagggctttac
accgccgaggggtaccgcatcaccgcccactattacgctggaaagaagcggggagtcagg
atccggctggacaacggggccgagcttgtgggcgcttgggaaagccaccgactcctcacc
ccagagggctggcggctcatgcgggagctgaagccgggggatgtggttttaggcaaactc
gtcccttcccacggggaaggcgggctccccatcccggaggccaagggcctctccttaagg
accaacgcccgcaacctccccttgcccgaaaggatgtccgaggaccttgccctcttcctc
gggatgctggccgccgacgggtccacggtggaggccacgggcttcgtgggcatcgccacc
aaggaccccgatgtggaacgggtcttccaagaggtggcgggtaggctgtttggcgtggaa
cccaagtgcacggtagacaagcgcacgggggtgcgtaacctttacctcacctcccgccgc
ctggtgcgtttcgtggaggctctgatcggcaaaggggcggcgcaaaagcgggtgccctcc
cagatcctccagggaagccctggggagaagctggctttcctccggggcctcacgctggat
ggctatgttcacgccaatatgggcctcgtggtctacgagggcaggagccaacgtttggcc
tacgaggcggcggagctcgcccgcagcttcggtcttcccaaggtctaccaggggcggaag
aaggtccttgcccccaaggaaacttactacgtccactccgtggcggtttccggacccctc
caggaactcctcgagcccctagaagcccacaagcgggccaaggtggaggcccggtacaag
gtcttcgttccccaagaggtcctggccgccacccgcgtgggaacccatcacccgggatac
gtcagcttgaagtccgtgcggcaaagggaggcccaggcagtctataacaccaccgcggag
cgcctgggctggcccacggagatcctggcccaccgggtggtggaggtggaggaagtgggc
gaggtggagatgtacgacatcgaggtggaggaggtccaccgctacgtggtcaacggcctc
atctcccacaacaccatcaacctccctaaccacgccacggtggaggacgtggaggccgcc
tacaccgaggcctaccgcacggggtgcaaggggatcaccgtctaccgggacggctcccgg
gagttccaggtcctcacggtgaagaaggaggctaaagaggagaaggcggggaaaacgccg
gaggaggcaaagccccaagaggccagggcccacgagcccggcaggcccgtctacgagcgg
cccggccgcctcatgggcttcaccgacatggtcaagctcttcgcccccgacgggtccaag
cggagcttcctcgtcacggtgaacaccctggagggccggcccattgaggtcatcctcacc
tcgggcaaggccggggacgaggcgaacgccgattcggaggccctgggccgggtggtctcc
atcgccctccagtacggggtgcccccggaggccattgtccggacgcttcggggcatcaac
ggggggctttacggcacctaccagggcaggctcgtctccagcaaggcggacctcatcgcc
gtggccctggagaccgtcccccagatggccccaggggccccggaggacctctcctccgcc
cccgtcctctcgggcggcgggatcgccctggccggggccgccccctgcccctcctgcgga
gagaaggccctggtgcgggaggaggggtgctggaagtgccaggcctgcggctacgccaag
tgcggctga

DBGET integrated database retrieval system