Tupaia chinensis (Chinese tree shrew): 102468736
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Entry
102468736 CDS
T02978
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2 alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup04137
Mitophagy - animal
tup04140
Autophagy - animal
tup04141
Protein processing in endoplasmic reticulum
tup04210
Apoptosis
tup04932
Non-alcoholic fatty liver disease
tup05010
Alzheimer disease
tup05012
Parkinson disease
tup05014
Amyotrophic lateral sclerosis
tup05020
Prion disease
tup05022
Pathways of neurodegeneration - multiple diseases
tup05160
Hepatitis C
tup05162
Measles
tup05168
Herpes simplex virus 1 infection
tup05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102468736 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102468736 (EIF2AK3)
04137 Mitophagy - animal
102468736 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
102468736 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
102468736 (EIF2AK3)
05162 Measles
102468736 (EIF2AK3)
05168 Herpes simplex virus 1 infection
102468736 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
102468736 (EIF2AK3)
05012 Parkinson disease
102468736 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
102468736 (EIF2AK3)
05020 Prion disease
102468736 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
102468736 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102468736 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102468736 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102468736 (EIF2AK3)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102468736 (EIF2AK3)
Protein kinases [BR:
tup01001
]
Serine/threonine kinases: Other
PEK family [OT]
102468736 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
102468736
NCBI-ProteinID:
XP_014439633
LinkDB
All DBs
Position
Un
AA seq
1115 aa
AA seq
DB search
MERATHPGPLARALLLQLLLGLAARTVAVGRSRDLPAPTAKAAFGLGAAAAPTSAARVPA
TGAVAAAEVTVEDAEALPAAAGEQEPRGPEPDDEAELQPRGRSLVIISTLDGRIAALDPE
NHGKKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMETVPFTVESL
LESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDSDEMEQEEDILLLQRT
QKTVRAVGPRSGNEKWNFSVGHFELRYIPDLETRAGFIESTFKPSGNKEESKIISDVDEQ
EAALMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLIKDGKVIPISLFDDTSY
TSNDELLKDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKALESVNSEN
AIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRERNKRSTQITVRFLDSPNYNKNIRKKDPVLLLHWWKEIVGTILFCIIATTFIVR
RLFHPHPHRQRKESETQCQTENKYDSVSGESNDSSWNDIKNSGYVSRYLTDFEPIQCMGR
GGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEA
PPEKWQEKMDEIWLKDESTDWPLSSPSPIEAPSVKIRRVDPFSTKERIEIIAPSPRRSRS
FSVGISCGQTNSSESQFSPLEFSGTDHGDISRSVDAAYNLQDSCLTDCDMEDGTMDGNDE
GHSFELCPSEAASYARSRERTSSSIVFEDSGCDNASSKEDPKTNQLRIGNHCVNKLTAVK
YSSSKSSSEATLSISPPRPTTLSLDLTRNTAEKLQPSSPKVYLYIQMQLCRKENLKDWMN
RRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVGDFGLVTA
MDQDEEEQMVLTPMPAYARHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLILFELLYPF
STQMERVRTLTDVRNLKFPPLFSQKYPREYVMVQDMLSPSPMERPEATDIIDNAVFEELE
FPGKTVLRQRSRSLSSSGTKPSRQSSNTLSPLPGS
NT seq
3348 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccacccggggccgctggcgcgggcgctgctgctacagctgctgctg
gggcttgcggcgcggacagtggcggtggggcgcagccgcgacctccccgcgcccacggcg
aaggcggcgttcggcttgggggccgcggccgctcctacgtccgccgcgcgggtgccggcg
accggggcggtggctgcggccgaagtgactgtggaagacgccgaggcgctgccggcggcc
gcgggggagcaggaaccgcggggaccggaacccgatgacgaggctgagctgcagcctcgc
ggcaggtcattagtaattatcagcactttagatgggcgaattgctgccttggatcctgag
aatcatggcaaaaagcagtgggatttggatgtgggatctggttccttggtttcatccagc
cttagcaaaccagaggtatttgggaataagatgatcattccttcgctggatggagacctc
ttccagtgggaccgagatcgtgagagcatggaaacagttccgttcacagtcgaatcactt
cttgaatcttcttataaatttggagatgatgttgttttggttggaggaaaatctctcact
acttatggactcagcgcttacagtggaaaggtgcggtatatttgttcagctttgggttgt
cgccagtgggatagtgatgaaatggagcaagaagaagacatcttgcttctgcaacgcacc
cagaaaaccgttcgagctgttggacctcgtagtggcaatgagaagtggaatttcagtgtt
ggccactttgaacttcggtatattccagacttggaaactagagccggatttattgaaagc
acctttaaacccagtgggaacaaagaagagtctaaaattatttcagatgtggacgaacag
gaagctgccctgatggacacagtgataaaggtctccgttgctgattggaaggttatggca
tttagtaaaaagggaggacatctggaatgggaataccagttttgtactccaattgcatct
gcctggttgattaaagatggcaaggtcattcccattagtctttttgatgatacaagttat
acatctaatgatgaacttttaaaagatgaagaagacatcgtagaagctgcccgaggagcc
acagagaacagtgtttacttgggaatgtatagaggccagttgtacttgcagtcatcagtc
agaatttcagaaaagtttccaacgagtcccaaagccttggaatccgtgaatagtgaaaat
gcaattattcctttgccaacaatcaaatggaagcccttaatacattctccttccagaact
cctgtcttggtaggatctgatgaatttgacaaatgtcttagtaatgataagttttctcat
gaagaatatagtaatggtgcactttccatcttacagtatccatatgataacggttattac
ctaccatactacaagagggagaggaacaaacggagcacacagatcacagtcagattcctc
gacagccctaattacaacaagaacatccgcaaaaaggatccggtactcctcttacactgg
tggaaagagatagttgggacgattttattttgtatcatagcaacgacgttcattgtgcgc
agacttttccaccctcatcctcacagacaaaggaaggaatctgaaactcagtgtcaaact
gaaaataaatatgattctgtaagtggtgaatccaatgacagtagctggaatgacataaaa
aactctggatatgtatcacggtatctaacagattttgaaccaattcagtgcatgggtcgc
ggcggctttggagtggtttttgaagctagaaacaaagtagatgactgcaattacgccatc
aagaggatccgtcttcccaatagggaattggctcgggaaaaagtaatgagagaagttaaa
gccttagccaagcttgagcatccgggaattgtgagatatttcaatgcctggctggaagca
ccaccagagaagtggcaagaaaagatggatgaaatttggctgaaagatgaaagcacagac
tggccactcagctctccgagcccaattgaggcaccatcagttaaaatacgcagagtggat
cctttttctacaaaagaacgtatagaaatcatagctccttctccacgaagaagcaggtct
ttttcggtgggtatttcctgtggtcagacaaattcatccgagagccagttctctcctttg
gaattctctggaacagaccatggagacatcagtaggtcagtggatgcagcctacaacctc
caggacagttgccttacagactgtgacatggaagatggtaccatggatggcaatgacgag
ggacactcctttgaactctgtccttctgaagctgcttcttatgcaaggtccagggagaga
acttcctcttctatagtgtttgaagattctggctgtgataatgcatccagtaaagaagat
cctaaaaccaaccaactgcgtattggcaaccattgtgtcaataaactaactgctgtcaag
tactccagtagcaaatcttcttctgaagcgaccttgtctatttctcctccaagaccaacc
actttaagtttagatctcacaagaaacactgcagaaaaactccagcccagttccccaaag
gtgtatctttacattcagatgcagctatgccgaaaggaaaacctcaaagactggatgaac
agacggtgtaccattgaggagcgagaaaggagcgtgtgtctgcacatcttcctgcagatc
gcagaggcagtggagtttctgcacagtaaaggactcatgcatagggacctcaagccttcc
aatatattctttacaatggacgacgtggtcaaggttggcgactttggattagtgactgcc
atggaccaagacgaggaagagcagatggttctgaccccaatgccagcatatgccagacac
acgggacaagtagggaccaagctgtacatgagcccagagcagattcatggaaacaactac
tctcataaagtggacatcttttctttaggcctgattctatttgaattgctctacccattc
agcactcagatggagagagtcaggacattaactgatgtaagaaatcttaagtttccacca
ctgttttctcagaaatatcctcgtgagtatgtgatggttcaagacatgctctctccatcc
cccatggaacggcctgaagctacagacatcattgacaatgctgtgtttgaggagttggag
tttccagggaaaacagtgctccgacagaggtcccgctcgttgagttcatcaggaaccaaa
ccttccagacagtccagcaacaccctcagccctttgccaggcagttag
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