KEGG   Tupaia chinensis (Chinese tree shrew): 102482054
Entry
102482054         CDS       T02978                                 
Symbol
MAP2K6
Name
(RefSeq) mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup04010  MAPK signaling pathway
tup04015  Rap1 signaling pathway
tup04218  Cellular senescence
tup04380  Osteoclast differentiation
tup04620  Toll-like receptor signaling pathway
tup04664  Fc epsilon RI signaling pathway
tup04668  TNF signaling pathway
tup04750  Inflammatory mediator regulation of TRP channels
tup04912  GnRH signaling pathway
tup04935  Growth hormone synthesis, secretion and action
tup04936  Alcoholic liver disease
tup05014  Amyotrophic lateral sclerosis
tup05022  Pathways of neurodegeneration - multiple diseases
tup05132  Salmonella infection
tup05135  Yersinia infection
tup05145  Toxoplasmosis
tup05161  Hepatitis B
tup05163  Human cytomegalovirus infection
tup05167  Kaposi sarcoma-associated herpesvirus infection
tup05169  Epstein-Barr virus infection
tup05170  Human immunodeficiency virus 1 infection
tup05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tup05417  Lipid and atherosclerosis
tup05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tup00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102482054 (MAP2K6)
   04015 Rap1 signaling pathway
    102482054 (MAP2K6)
   04668 TNF signaling pathway
    102482054 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    102482054 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    102482054 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    102482054 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102482054 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    102482054 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102482054 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102482054 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102482054 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102482054 (MAP2K6)
   05161 Hepatitis B
    102482054 (MAP2K6)
   05163 Human cytomegalovirus infection
    102482054 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102482054 (MAP2K6)
   05169 Epstein-Barr virus infection
    102482054 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102482054 (MAP2K6)
   05135 Yersinia infection
    102482054 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102482054 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    102482054 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    102482054 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102482054 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    102482054 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102482054 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tup01001]
    102482054 (MAP2K6)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     102482054 (MAP2K6)
Protein kinases [BR:tup01001]
 Serine/threonine kinases: STE group
  STE7 family
   102482054 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 102482054
NCBI-ProteinID: XP_014442639
LinkDB
Position
Un
AA seq 334 aa
MSFPIGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKSILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtcttttcctataggcaagaagcgaaaccctggccttaaaatccccaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagatttagattccaaggcttgtatttct
atcggaaatcagaactttgaggtaaaggcagatgatctggagccaataatggaactggga
cgaggtgcatacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaacgactactgatggatttg
gatatttccatgaggacagtggactgtcctttcactgtcaccttttatggtgcactcttc
cgggagggtgatgtgtggatctgcatggagctcatggatacttcgctagacaaattctac
aaacaagtgattgataaaggccaaacaatcccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttgcacagtaagctctctgtcattcatcgagacgtc
aaaccttccaacgtgctgattaatactctgggccaagtgaagatgtgtgattttggaatc
agtggctacctggtggactctgttgctaaaacaattgatgcaggctgcaaaccgtacatg
gctcctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtttgggcatcacgatgatcgagttggccatccttcggtttccctatgattcgtgg
ggaaccccttttcagcagctcaaacaggtggtagaggagccatcaccacaactcccagca
gacaagttctctgcagagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagaacttatgcaacatccatttttcactctacatgaatccaaa
ggaacagacgtggcatcttttgtaaaatcgattcttggagactaa

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