KEGG   Tupaia chinensis (Chinese tree shrew): 102498317
Entry
102498317         CDS       T02978                                 
Symbol
CACNA1B
Name
(RefSeq) calcium voltage-gated channel subunit alpha1 B
  KO
K04849  voltage-dependent calcium channel N type alpha-1B
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup04010  MAPK signaling pathway
tup04020  Calcium signaling pathway
tup04721  Synaptic vesicle cycle
tup04723  Retrograde endocannabinoid signaling
tup04725  Cholinergic synapse
tup04726  Serotonergic synapse
tup04727  GABAergic synapse
tup04728  Dopaminergic synapse
tup04930  Type II diabetes mellitus
tup05016  Huntington disease
tup05020  Prion disease
tup05022  Pathways of neurodegeneration - multiple diseases
tup05032  Morphine addiction
tup05033  Nicotine addiction
tup05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:tup00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102498317 (CACNA1B)
   04020 Calcium signaling pathway
    102498317 (CACNA1B)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    102498317 (CACNA1B)
   04725 Cholinergic synapse
    102498317 (CACNA1B)
   04728 Dopaminergic synapse
    102498317 (CACNA1B)
   04726 Serotonergic synapse
    102498317 (CACNA1B)
   04723 Retrograde endocannabinoid signaling
    102498317 (CACNA1B)
   04721 Synaptic vesicle cycle
    102498317 (CACNA1B)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    102498317 (CACNA1B)
  09164 Neurodegenerative disease
   05016 Huntington disease
    102498317 (CACNA1B)
   05020 Prion disease
    102498317 (CACNA1B)
   05022 Pathways of neurodegeneration - multiple diseases
    102498317 (CACNA1B)
  09165 Substance dependence
   05032 Morphine addiction
    102498317 (CACNA1B)
   05033 Nicotine addiction
    102498317 (CACNA1B)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102498317 (CACNA1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:tup04040]
    102498317 (CACNA1B)
Ion channels [BR:tup04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   102498317 (CACNA1B)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel Phage_TAC_15
Other DBs
NCBI-GeneID: 102498317
NCBI-ProteinID: XP_006163418
LinkDB
Position
Un
AA seq 2361 aa
MWLRVPSGGVRLRGHSPRSGSGGAQPPPLAPGVGRSRAEALSAVLTAADAEGLVAQTAEA
WPGAALGTGTGMGTRAAGGLNPHTPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLD
DTEPYFIGIFCFEAGMKIVALGFALHRGSYLRNGWNVMDFVVVLTGILATAGTDFDLRTL
RAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGRFHK
ACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCI
TMEGWTDILYSTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRA
FLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDKNAEEKSPLDAVLKRAATKKSRNDLIH
AEEGADRLADLCALGSPFARASLKSGKTDSSSYFRRKEKMFRFFIRRLVKAQSFYWAVLC
VVALNTLCVAVVHHNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFD
CGVIVGSIFEVVWAAIKPGTSFGISVLRALRLLRIFKVTKYWNSLRNLVVSLLNSMKSII
SLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQILTGEDWNAVMY
HGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAAN
QKLALQKAKEVAEVSPMSAANISIAAFVKQTRGTVSRSSSVSSVNSPRQQNSAKARSVWE
QRASQLRLQNLRASCEALYSEMDPEERLHYATSRHLRPDMKTHLDRPLEVEPGRDGPRAS
TGPKARSEGVEATEGGDPPRRHHRHRDKDRALSTAPPAGDQDGADAPKAESGGQVAREER
ARPRRSCSKEDAGPRGVRGGRGGERARPRRSCSKEAAGPREVRGERGRGLGSEGPRRHHR
HGSPEEAAEREPRRHRGHRHADQGKEGTTLGAKGERRARHRGGLRAGPRETENGEEPARR
HRVRHKVQSPPEGTEKEAAGTAGGGKDKEPRNHHPMEPNCDLEASVMTAPAHTLHSTCLQ
KVEEQPEDADNQRNVTRTGSPPSDPSTVVHIPVTLTAPPGETEVIPSGNVDPESQAEGRK
EVEADEGMGSGPRPIVPYSSMFCLRPTNLLRRCCLYIVTMRYFEMVILVVIALSSIALAA
EDPVWTDSPRNNVLKYMDYIFTGVFTFEMVIKMVDLGLLLHPGAYFRDLWNVLDFIVVSG
ALVAFAFSGSKGKDISTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVY
MLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYD
NVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVN
IFVALIIITFQEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQNKQSFQYKTWTFVV
SPPFEYFIMAMIALNTAVLMMKFYDAPYEYELMLKGLNVVFTSMFSMECVLKIIAFGVLN
YFRDAWNVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILL
WTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLF
RSATGEAWHEIMLSCLSHRACDRLANASECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMD
NFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPAR
VAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISSVW
ANLPQKTLDLLVPPHRPGEMTVGKVYAALMIFDFYKQSKTSRDQARQAPGGLSQMGPVSL
FHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAVQTQQSGIKESVSWGTQRTQDTPC
EARPPLERGHSAEIPVGQSRTLAVDVQTALKDPDGEPQPGLESQGRAASMPRLAAETQHA
PDASPMKRSISTLAQRPHGVHLCSATLDRPAPSQATHHHHHRCHRRRDKKQRSLEKGPSL
SADTDGAPNSTAGPGLPPGDGPTGCRRERRRERGRSQERRQPSSSSSEKQRFYSCDRWGG
REPLPPRPSLSSHPTSPTAGQGPGPHTQDSGPASGSPLLPTSGASTAGRGGRRQLPQTPL
TPRPSITYKTAHSSPVHYGGAQTSLPAFSPGRLSRGLSEHNALLQRDTLSQPLAPGSRIG
SDPNLGQRLDSEAADHPLPEDTLTFEEAVATNSGRSSTATTVLWDSARAAGHGTATTTPT
KTTGASCAVIATPARSGTSHG
NT seq 7086 nt   +upstreamnt  +downstreamnt
atgtggctgcgtgtgccttcaggtggtgtgcgcctgcgcgggcactctccccggtctggc
tccgggggcgcacagccccctccgctggcgcccggggtcgggcggagccgggcggaggcg
ctgtccgcggtgctgacggccgcggatgcggaggggctggtagcccagactgcagaggcc
tggcctggcgctgccctcgggacggggacggggatggggacacgggcggcgggcggcctt
aacccgcacactccgttcgagtacatgatcctggccaccatcattgccaactgcatcgtg
ctggccctggagcagcacctccctgacggcgacaaaacacccatgtctgagcggctggac
gacacagagccctacttcattgggattttctgcttcgaggcggggatgaagatcgtcgcc
ctgggcttcgcactccacaggggctcctatctgcgcaatggctggaacgtcatggacttc
gtggtggtcctcacggggatccttgccacggccgggactgacttcgacctgcgaactttg
agggctgtgcgtgtgctaaggcccctgaagctggtgtctgggattccaagcttgcaggtg
gtgctcaagtccatcatgaaggccatggtcccgctcctgcagatcgggctgctgctcttc
ttcgccatcctcatgttcgccattataggcctcgagttctacatgggaagattccacaag
gcctgcttccccaacagcacagatgcagagcctgtgggtgacttcccctgtggcaaagag
gccccggcccggctgtgtgagggtgacaccgagtgtcgggagtactggccgggtcccaac
ttcggcatcaccaacttcgacaacatcctgtttgccatcctgacggtgttccagtgcatc
accatggagggctggaccgatatcctctacagcacgaatgacgcggctgggaatacctgg
aactggctctacttcatccccctcatcatcatcggctccttcttcatgctcaacctggtg
ctgggcgtgctctcaggagagttcgccaaggagcgagagcgggtggagaaccgccgcgcc
ttcctgaagctccgcaggcagcagcagattgagcgggagctcaatgggtacctggagtgg
atcttcaaggccgaggaagtcatgctggcagaggaggacaagaacgcagaggagaagtcc
cctctggatgcagtgttgaagagagcagccaccaagaagagccggaacgacctgattcac
gcagaggagggggcagaccggctcgcagacctctgtgccctcggatccccctttgcccgc
gccagcctcaagagtgggaagaccgacagctcgtcctacttccggaggaaggagaagatg
ttccggttcttcatccggcgcctggtgaaggcgcagagcttctactgggcagtgctgtgc
gtggtggccctgaacacgctgtgcgtggcggtggtgcaccacaaccagccgcagcggctc
accacggccctgtacttcgctgagtttgtgttcctgggcctcttcctcaccgagatgtcc
ctgaagatgtacggcctggggccccggagctacttccggtcctccttcaactgctttgac
tgtggggtcatcgtggggagcatctttgaggtggtctgggctgccatcaagccggggacc
tcctttgggatcagtgtgctccgggcgctccgcctgctgaggatcttcaaagtcaccaag
tactggaactctctgcggaacctggtggtgtctctgctcaactccatgaagtccatcatc
agcctcctcttcctgctcttcctgttcattgtggtcttcgctctgctgggcatgcagctg
ttcgggggccagttcaactttcaagatgagactccaactaccaactttgacaccttcccc
gccgccatcctcaccgtcttccagatcctgacaggagaggactggaacgcggtcatgtac
cacgggatcgagtcgcaaggtggcgtcagcaaaggcatgttctcgtccttctacttcatc
gtcttgacgctgtttggaaactacactctgctgaatgtctttctggccattgctgtggac
aacctcgccaacgcccaggaactgaccaaggatgaagaagagatggaagaagcggccaat
cagaagctggctctgcagaaggccaaggaagtggcggaagtcagccccatgtctgccgcg
aacatctccattgctgcttttgtaaagcaaactcgaggtactgtatctcgcagctcatct
gtctccagcgtaaactcacccaggcagcagaactcagccaaggcgcgctcggtgtgggag
cagcgggccagtcagttgcggctgcagaacctccgggccagctgcgaggcgctgtacagt
gagatggaccccgaggagaggctgcactacgctacctcgcgccacctgcggccggacatg
aagacgcacttggaccggcccctggaggtggagccgggtcgggatggcccacgggcttcc
acggggcccaaggcccggtctgagggcgtggaggccactgagggcggggacccgccacgt
aggcaccaccggcaccgcgacaaggacagggctctgtccacagcccccccggcaggggac
caggatggcgcagacgccccgaaggcagagagtggagggcaggtggcccgggaggagcgg
gcgcgaccacgccgcagctgcagcaaggaggacgcgggcccccggggggtgcgaggcggg
cgcgggggggagcgggcgcgcccacgccgcagctgcagcaaggaggccgcgggcccccgt
gaggtgcgaggcgagcgcggccggggcctgggctctgagggcccccggcgccatcaccgg
catgggtccccggaggaggcagctgagcgagagccccggcgccaccgtggccaccggcac
gccgaccagggcaaagagggcaccaccctgggggccaagggtgagcggcgagctcggcat
cgcggaggcctccgggccggccccagagagacggagaacggcgaggagcctgcacggcgg
caccgggtccggcacaaggtgcagtccccgcccgagggcacggagaaggaggccgcgggg
actgcgggagggggcaaggacaaggagccccggaaccaccatcccatggagccgaactgc
gacctggaagccagtgtgatgacggcccctgcacacacactgcacagcacgtgtctccaa
aaggtggaggagcagccagaggatgcagacaaccagcggaatgtcactcggacgggcagc
cccccctcagacccaagcaccgtggtgcacatccccgtgacactgacagccccccccggg
gagaccgaggtcattcccagtggtaacgtggacccagaaagccaagcagagggcaggaag
gaggtggaagccgacgagggcatggggagcggcccccggcccatcgtcccatacagctca
atgttctgcttacgccccaccaacctgctccgtcgctgctgcctctacatcgtgaccatg
cgctactttgagatggtcattctcgtggtcatcgccctgagcagcattgccctggccgcc
gaggaccccgtgtggacagactcacctagaaacaatgttctgaaatacatggattacata
ttcacgggcgtcttcaccttcgagatggtgatcaagatggttgacctgggactgctgctg
caccctggggcctacttccgggacctgtggaacgttctggacttcatcgtggtcagtggg
gccctcgtggcatttgccttctcaggatccaaagggaaagacatcagcaccatcaagtcc
ctgagagtcctgcgtgtcctgcggcccctgaagaccatcaagcggctgcccaagctcaag
gccgtgtttgactgtgttgtgaactccctgaagaacgtgctcaacatcctgatcgtctac
atgctcttcatgttcatctttgccgtcatcgctgtgcagctgttcaaggggaagtttttc
tactgcacggacgagtccaaggagctggagagggactgcaggggtcagtatttggattat
gagaaagaggaagtggaggctcagccacggcagtggaagaaatacgactttcattacgac
aatgtgctctgggccttgctgacgctgttcacggtgtccacaggcgaggggtggcccatg
gtgctgaaacactctgtggatgccacctatgaggagcaggggccgagccccgggtaccga
atggagctctccatcttctacgtggtctacttcgtggtcttccccttcttctttgtcaac
atctttgtggccttgatcatcatcaccttccaggagcagggggacaaggtgatgtctgag
tgcagcctggagaagaacgagagggcttgcattgacttcgccatcagcgccaagcccctg
acacggtacatgccgcagaacaagcagtctttccagtataagacgtggacgttcgtggtc
tccccgcccttcgagtacttcataatggccatgatagccctcaacacagcagtgctgatg
atgaagttctacgatgcaccctacgagtacgagctgatgctgaagggcctgaacgtcgtg
ttcacctccatgttctccatggagtgcgtgctgaagatcattgccttcggggtgctgaac
tacttcagagatgcctggaatgtctttgacttcgtcaccgtgctggggagtattactgac
attttagtaacagagattgcggaaacgaacaacttcatcaacctcagcttcctgcgcctg
ttccgagccgcgcggctcatcaagctgctgcgtcagggctacaccatccgcatcctgctg
tggaccttcgtccagtccttcaaggccctgccctacgtgtgcttgctcatcgccatgctg
ttcttcatctacgccatcattggcatgcaggtctttggaaacatcgccctggatgacgac
accagcatcaacaggcacaacaacttccggacattcctgcaggccctgatgctgctgttc
aggagtgccaccggggaggcctggcatgagatcatgctgtcttgtctcagccaccgggcc
tgtgacaggcttgccaacgccagcgagtgcgggagcgactttgcctacttctacttcgtc
tccttcatcttcctgtgctccttcctgatgttgaacctctttgtggctgtgatcatggat
aatttcgagtacctcacacgggactcgtccatcctcgggccacaccacctggacgagttc
atccgggtctgggctgaatatgacccggctgcgtgtgggcgcatcagttacaatgacatg
tttgagatgctgaaacacatgtccccacctctggggctggggaagaaatgccctgctcga
gttgcatataagcgcctggtccgcatgaacatgcccatctccaacgaggacatgacggtc
cacttcacgtccacgctgatggcccttatccggactgcactggagatcaagctggcccca
gctgggacaaagcaacaccagtgtgatgcagagctgaggaaggagatctcctccgtgtgg
gccaatctgcctcagaagaccttggacctgctggtgccaccccacaggcctggtgagatg
acagtggggaaggtgtacgctgcgttgatgatattcgacttctacaagcagagcaagacc
agcagagaccaggctcgccaagcacctgggggcctgtcccagatgggtcctgtgtcactg
ttccaccctctgaaggccaccctggagcagactcagccagctgtcctccgaggagcccgg
gtcttccttcgtcagaaaagctccacctccctcagcaacggtggggctgtacaaacccaa
cagagtggcatcaaagagtctgtttcctggggcactcagaggacacaggacacaccctgc
gaggccaggcctcccctagagcgcggccattcagcggagatccctgtggggcagtcaagg
acactggctgtggatgtccagacagccctgaaggaccccgatggggagccccagcctggg
ctggagagccagggccgtgctgcgtccatgcctcgcctggcagcagagacacagcacgcc
ccagatgccagtcccatgaagcgctccatctccacgttggcccagcgcccccacggggtc
catctctgcagtgccaccctggaccgccctgccccgagccaggccacccatcaccaccac
caccgctgccaccgccgcagggacaagaagcagagatccctagagaaggggccgagcctc
tctgctgacacggacggtgcacccaacagcactgcagggcccgggctgcccccaggagat
gggcccacaggctgcaggcgggagcgacggcgggagcggggccggtcccaagagcggagg
cagccctcctcctcctcctcagagaagcagcgcttctactcctgtgaccgctggggtggc
cgtgagcccctgccgcccaggccatccctcagtagccaccctacatcgccaacagctggg
caggggccagggccccacacgcaggatagtggaccagctagtgggagccccctgctgcca
acatctggtgctagcactgcaggccgtggtgggcgcaggcagctgccccagacccccctg
accccccgtcccagcatcacctacaagacggcccattcctcacctgtccactacggcggg
gctcagaccagcctccccgccttctcccccggccggctgagtcgcggcctttctgagcac
aacgccttgctccagagagacacccttagccagcccttggcccctggctctcgcattggc
tctgaccctaacctgggccagcgcctggacagtgaggctgctgaccaccccctgcctgag
gacacactcacctttgaggaagctgtggccaccaactcaggccgctcttcaacggctacc
actgtactctgggactcggctcgggcagccgggcacggcacagctaccaccaccccgacc
aagaccactggtgctagctgtgccgtgatcgccacacctgcacgcagcggcacgtcccac
ggatga

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