Tachysurus vachellii: 132843241 Help Entry 132843241         CDS       T09596                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism tvc  Tachysurus vachellii Pathway tvc04020   Calcium signaling pathway tvc04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:tvc00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     132843241 (ryr3)    04020 Calcium signaling pathway     132843241 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:tvc04040]     132843241 (ryr3) Ion channels [BR:tvc04040]  Voltage-gated cation channels   Ryanodine receptor    132843241 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Motif Other DBs NCBI-GeneID:  132843241 NCBI-ProteinID:  XP_060722410 LinkDB All DBs Position 3:25024817..25099575 Genome browser AA seq 4860 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVATIQKENRKFCLSAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLANTDQNGEGTPDHERWAGQGGGHRTLLYGHAILLRHSF SGMYLACLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSSERFLHLSISNGNIQVDASFMQTLWNVQPTCSGSNVAVGYVLGGHVMRLFHGHDELLT IPGADQSAEQQWLVNYETGKTGSRARSLWRLEPLRISWSGSHIRWGQPFRLRHLSTGHYL GQTEDRGLVLLEREKSDTTATSFCFRPSKEKVDSGSKRDVEGMGVAEIKYGDSVCFIMHV ASGLWLSYMAPDAKSSRLGPLKRRAFLYPEGHMDDGLILQLCQHEESRAARIIRNTTLLF TQFIGGLDELKGEKASGVNLPVGEVLQTLNDLITYFQQPDSELEHEEKQRQLRSLIKRQD LFKEEGMLTLVSICIDRLNMYNSAAEFEEFAGEEAGEAWKDVLNLLYELLAALIRGNRPN CTQFSRKLDWLISKLERLESSSGILEALHCILTESPEALNIIQRDHIRSIISLLYKHGRN HKILDILCSLCVCNGVAVRANQNIICDYLLPRRDLLLQTRLVNDVQSMRPNIFLGISEGS AQYKKWYYELMIDQVDHFVTSESTHLRVGWASTKGYAPYPGGGEGWGGNGVGDDLYSYAF DGLHLWSGRIQRAVASINQHLLTSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGF FFPVVSFSAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKRDMEGV RYLLGTTQFLSQASFIPVPVNTSQTVLPPHLENVRNKLAENIHELWGMNKIELGWTYGKV RDDNKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVVQINVNAEDDLKKIKLP KDYVMSNGYKPAPLELSDVKLTPGQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSR RNPRLVPYSLLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQEVAHVMEKHGVENVRFFR VEKCYAVQSGKWYFEFEAVTGGEMCVGWARPSCRPDVELGIDDKAYVFDGYRGRRVHMGS HFFGRTWNKGDVVGCMINMEDKSMIFTLNGEIIITNKGSELCFTDFETEDGFIPVCSLGL SQIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPTFVNVPVEHEHIE VTRIDGTVDSPPCLKVSHKTFGTQASNNDMIYCRLSMPVEFYSSPRKITNMNEVSIDGQK SKKDDSGKTDYSSITKYFYSVRVFAGQDPASIWVGWVTPDYHYYSKKFNLSKVRTVTVTL GDERGRVHESVRRSNCYMVCAGEITSSSSGRSNADLIIGCHIDLASGLVSFTANNKELPI AYQVEPNTKLFPAVFVQPTSPNLFQFEFPKIKDAMPLSSAIFTSLRNNPEPQCPPRLDVQ TIVAVLWSRMPNIFLSVETARVSERHGWVVQCLEPLQMMAVHIPEENRCIDVMELSEDEV LRQFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLTGQLREGFYDVLISI HLETAKEAKLMMKNEFIIPITEETRSIRLFSDDSKRHTLPGVGLSTSLSPRFNFTPPCFI TTKREHIYSPQIPLGILKEKAISMLTEAVQGGGAHIRDPVGGSVEYQFVPILKLIATLLI MGSLSSEEVRIILLLIEPNVFGEIKEEETQLLAVEEPAEKEEASSNEEKAVEAGEEESKE HKQPPKGLLEKSLPESVKHQMCELLHYFCDCELKQRIESIVAFSDIFVAKLQFNQKFRYN ELMQALNMSAAVTAKKTKEFRSPPQEQINMLLDFSAGEDCPCPEDIQEELHAFHDDLRLH CGIPMEEEEEEPDTSIKGRLLSLLYKIKGRPQKTEEQPSEEEQAAPTNLKELISQTMVSW AQECKIQNPKLVRSMFSLLRRQYDGIGELLRAMRKSYTISEKSVQDAINLLASLGQIRSL LSVRMGEEEGQLMIDGLGDIMNNKVFYQHPNLMRIMGMHETVMEVMVNVLGGDKSKEIAF PKMVASCCRFLCYFCRISRENQKAMFEHLSYLLENSSVGLACTAMRGSTPLDVAASSVMD NNSLALALEEPDLEKVVMYLAGCGLQSCPMLVAKGYPDIGWNPIEGERYLSFLRFAVFVN GESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMLEAIKISEDPALDLPNLPGGGA PVPGEDGEEEELAHMGNSIMSFYSALIDLLGRCAPEMHLINTGKGEALRIRAILRSLVPT KDLVGIISIPLKVPIINKDGSVTEPDMNSSFCPEHKSPMVLFLDRVYGIEDQSFLLNLLE VGFLPDFRVSASLDTEVLSTTETALALNRYIGSAVLPLLTRCASLFAHTEHYTTLMDSTL QTIYRLSKGRSLTKAQRDSIEECLLAICKHLRPSMLQQLLRRLVFDVPQLTEYCKMPIKL LSNHYEQNWKYYCLPSGLGSYGMASEEELHLTTKLFWGLFDALSQKKYDAELFKMAMMCL SAIGGAIPPDYVYISPATTLVKQVSVDSQGNFDPKPINTANISLPEKLDYIANKYAEHCH EKWSSEKFALGWTAGEKVDDQAKTHPLLKPYKALSEKERETYRYPVKESLKCMLAMGWTI ERTKEGDAMFQQREAEKQIKTSEPSQGDGFHPAPVELENVTLSRELQSMVETVAENYHNI WANKKKMELSSKGGGTHPLLVPYDTLTAKEKFRDREKSQELFKFLQLNGYAISRGLKELE HDSSSMEKRIAYKFLKRLLSYVDSAQEFIAHLEAMATSGKTDKSPHEQEIKFFAKVLLPL LDQYFKNHCLYFLSSPSINLSSSGYASNKEKEMITSLFCKLASLVRHRISLFGSDSATMV SCLLILAHSLDFRTVMKSGSELVKAGVRTFFENAAEDLEKTMENLKLGKMGQSRTQMKGV AQIINYTSVALLPILTALFQHITEHQFGADLLLDDVQLSCYRILTSLYSLGTGKNIYVEK QLPVLGECLATLVGAMPVAFLEPHLNMHNPRSVFNTKTPRERAILSMPDTVEEMCPEMPR VDGLLKDIHDISESGARYTEMPHVIEVILPMLCNYLSYWWEKGPENSPNHESCCTTVTSE HLSLILGDILKILNNNLGIDEASWMKRLAVYTQPIISKAGADLLRTHFLPTLEKLKKKTV KIVAEEEMIRAESKADTQEAELQILDEFAVLCRDLYAFYPMLIRYVDNNRSKWLKKPSTD STELFNMVAEIFILWCKSHNFKREEQNFVVQNEINNLAFLTGDNKTKMSKSGGQDQERKG KKRRGELYSIQTSLIVAAHKKLLPIGLNMCTAGDQELISLAKIRYSLKDTDDEVKDHLRQ NLHLQQKTEDPAVQWQLNLYKDVEVKGEEPINTDHIIAKIQGISAAVFHLEQVEQPLRCK KLVWQKHLSKQRKRAVVACFRMAPLYNLPRHRSINLFLTGYQKLWIVAEKYSFEEKLVQD LAKTPMAVEKEEEEAEAEVQPDPLNQLILHFSHNALTERSVQEVDPLYIAYADMMAKSCA EDEEAEEEEEKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGHLGPMVRYTL KLGISILNGGNVVVQQKMLDYLKEKRDAGFFKSLSGLMLSCSVLDLNAFERQKKAESLGM VTEEGSINASERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQSGNTTTVNIIIS TVDYLLRLQESISDFYWYYSGKDVIDEHGQLNFSKAMEVAKQIFNSLTEYIQGPCIGNQQ SLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMMLSLLEGNVVNG TIGKQMVDTLVESSSNVEMILKFFDMFLKLNNLTTSDNFKEYDPEGKGIISKKEFQKSME SQKQYTQSEIDYLLSCAEADENDMFNYMEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDS RLSTFLDLAESVLSYFEPYLGRIEIMGGAKRIERIYFEISESSREQWEKPQVKESKRQFI FDMVNEGSESEKMELFVNFCEDTIFEMQLASQISESGAVERPEEEEEQHSMLEDLSEEED QSLESASAFTVACASVKKKVSNFRQMLTIKNMRKQFKKFKKLTIKEMITGFFSFFWMLFT GFFKGIFSLIFGFFHIIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDIMELEKA ENGEIVVSTEMVQMAGTVDKLEPDAIIDLISPPTKREGKHGHEPGLGDVSEITTEASPRV EKKKCQKAVPEEPEPEKADTETHEKEDKAKEEKPEEPVAEEMLAPRKHHGPPKEEPPELM ATFFAGLEVYKTKMLNYLARNFYNLRMLALFVAFAINFILLFYKVTAETEDEDEEESWGG SDDDDEEDSDMEFYVLQEGTGYMAPTLTFLAILHTVISLLCVVGYYCLKVPLVVFKREKE IARKLEFDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYWDKFVKRKVINKYGDLYGAER IAELLGLDKSALDFDPTEEAVVKEASLLSWLSSIDTKYHIWKMGVVLTDNSYLYLIWYTT MSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFN FFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFD ITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFET HTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14583 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggagaaggggaagatgaaatccagttcttgcgaactgatgatgaagtg gtgctccagtgtgttgctactattcagaaggagaatcgtaaattctgcttgtctgcagag ggacttggaaatcgactgtgttacctcgagcccacttcagaagccaagtatgttcctcct gacctgtgcatctgtaactttgtactggagcagtctctctctgtgcgagctctgcaggag atgctggccaacacagaccaaaatggggaaggtactcctgatcatgagcgatgggcggga caggggggtggacatcggacactgctgtatggtcacgccatcctactaaggcattcattc agtggaatgtatctagcctgtctaaagacatcaaggtctctgacagacaagctgtcattt gatgtaggattacaggaggattcgacaggcgaagcctgttggtggaccattcatccagcc tccaaacaaaggtctgagggtgaaaaggttcgcattggtgatgatctcattttggtcagt gtgtcctcagagagattcctgcatctatcaatctccaatggaaacatacaagtggatgcg tctttcatgcaaacactgtggaatgtgcagcctacctgctctggcagcaatgtggcagtg ggatatgtactggggggacatgtgatgcgcctgttccatggacatgatgagctccttact ataccaggagcggaccagtctgccgagcagcagtggctggtgaactatgagactgggaaa acaggttccagggccaggtccctgtggagattagagccacttcggattagctggagtggg agccatattcggtggggtcaacctttccgcctgcgccatctctccactggtcactacctg ggtcagacagaggaccgtggcctggtactgctggaaagagagaagtctgacactactgcc acatcattctgcttcaggccaagcaaggagaaagtggactctggctcaaagcgagacgtt gaaggcatgggggtggcagagatcaagtacggtgattcggtctgcttcatcatgcatgtg gcgtcaggactgtggctgtcctatatggcaccagatgcaaaatcctcccgccttggacca ctcaagagaagagctttcctgtatccagagggccacatggatgatgggctgattctgcag ctctgccagcatgaagagtccagagcggctcgcatcatccgcaacaccactcttctcttc acccagttcatcggagggctggatgaactgaaaggtgagaaagcatcaggggtgaatctg ccagtgggagaagtactacaaactctgaacgacctcatcacctacttccaacaacctgac tcagagttggagcacgaggagaagcagaggcagttgcgttcgcttatcaaacgccaggac cttttcaaagaggagggaatgcttacactggtctctatctgcatcgaccgactcaacatg tacaacagtgctgctgagtttgaggagtttgcaggagaggaagcaggagaggcctggaag gacgtcctcaatctcctctatgagctgcttgctgccctgatccgaggaaacagacccaac tgtacgcagttctcacgcaaactggactggctgataagcaagctggagcggctggagtcc tcctcaggtattctggaggctctgcactgcatcctaacagagagtccagaggctcttaac ataatccagagagaccacattagatccatcatttcccttctctataaacatggacgcaac cacaagatcctggacattctctgctctctttgtgtctgcaatggagtggcagtccgagcc aatcagaacatcatctgtgactacctacttcccagacgagacctgctgctgcaaacacga ttggtcaatgatgtgcaaagcatgagacccaacatcttcctaggcataagtgaaggatca gctcagtataagaagtggtactatgagctgatgattgatcaggtggatcattttgtcaca agtgaatccactcatcttcgtgtaggctgggccagcactaaaggctatgccccctaccct ggtggtggagagggctgggggggcaacggtgttggtgatgatctctactcctatgccttt gatggacttcatctgtggtcagggcgaatccaacgggccgtggcctccattaaccagcac ttgctgacctcggatgatgtggtgagctgctgcctggacctcggtgcgcccagcatgtcc ttccgcattaacggccagcctgtgcagggaatgttcgaggacttcaacacggacggtttc ttcttccctgttgtcagcttctcagcaggggtcaaggttcgtttcttgttgggtggtcgc catggtgaattcaagtttctaccccctgctggctatgcaccttgttatgaagcccttctc cccaaagaaaagatgcgggtggagcctgtgaaggagtataagagggatatggagggagtg aggtacttgctgggaaccactcaattcctttctcaagcatccttcattcctgttcctgtc aataccagccagactgttctgcctccacaccttgaaaatgtacgcaataagctagctgag aacatccatgaactctggggtatgaacaaaatcgagcttggctggacctatggcaaggta cgcgatgacaacaagaggcagcatccttgcctggttgacttctccaagctgcctgaaact gaaaaaaattataacctgcaaatgtcaacagaaactttaaagaccttactggctttggga tgtcatgttgtacaaatcaatgtcaatgctgaagatgacctgaagaagatcaaacttccc aaagactatgtgatgtcaaatggttataagcctgcaccactagaactttctgatgtgaaa ctgacacctggtcaggaatttctggttgataaactagctgaaaacgctcataatgtttgg gccaaagatcgcattaagcaaggatggacctatggtattcagcaggatttaaagagtaga cgcaatcctcgtctggtgccatattcattgttagatgaacgcacaaagaagtctaacaga gacagccttcgagaggccatcagaacactaattggttacggatacaacattgagcctcca gatcaagaggtggcccatgtgatggagaagcatggtgttgaaaatgttcgtttcttccgt gtggagaaatgctatgcagtgcaatcagggaaatggtattttgagtttgaggctgttact ggaggagaaatgtgcgtaggctgggctcggcccagctgtagacctgatgttgaattgggc atagatgacaaagcctatgtttttgatggctaccgtggtcgacgggtacacatgggcagc cacttctttgggagaacatggaacaagggtgacgtggtgggatgcatgattaacatggaa gataagtccatgatctttactctcaatggagagattatcatcaccaacaagggttctgag ctctgcttcactgactttgagactgaagatggcttcatcccagtttgcagtcttgggctc tcgcagattggccgtatgaacctgggcaaagacgccagcacctttaaatactacaccatg tgtggccttcaggagggttttgagcctttcgctgtcaacatgaatcgagagatcactatg tggttcagcaaacgccttcctacgtttgtcaatgtgcctgtggaacatgagcacattgag gtgaccagaattgatgggactgtggactcaccaccatgtctgaaggtgagccataagacc tttggaactcaagctagcaacaacgacatgatctactgccgcttgagcatgcctgtcgag ttttattctagtccccggaaaatcactaatatgaacgaggtgagcattgatggacaaaaa tctaagaaggatgacagcgggaagactgactatagcagcattacaaagtatttctactca gtgagagtgtttgcaggtcaggaccctgcctcgatatgggtaggctgggtaacaccagac taccactactacagcaagaaatttaacctgagcaaagtccgtacagttactgtgactcta ggggacgagcgtggccgcgttcatgagagtgtgaggaggagtaattgttacatggtgtgt gctggtgaaattacaagcagctcttctggacgaagcaatgctgacctcataattggatgt catattgatcttgcctctggccttgtttcattcactgccaacaacaaagagctgcctatt gcatatcaggttgagcccaacacaaaactgttccctgctgtgtttgttcagcccacaagc cccaacctgtttcagtttgaatttccaaaaatcaaagatgccatgccactgtcttcagcc atttttacaagtcttcgcaataacccagagccacagtgtcctccacggctggatgtacag accattgtagctgttctgtggagcaggatgcccaacattttcctctcagtggagacagca cgggtcagcgagaggcatggctgggtggttcagtgtctggagcccttgcagatgatggca gtgcacattcctgaggaaaacaggtgcatagacgtcatggaactctcagaggacgaggtc ttgcgacagtttcactaccacactctgaagctctactgtgctctctgtgctctgggaaac actcgtgtggcccatgctctctgtagccacctagaccaatcacagctcctttacaccatt gacaaccaatacctgacaggacagctgcgcgagggcttctatgatgttcttatcagcatc cacctggagacagcaaaagaagcaaaactcatgatgaagaatgagtttatcatacctatc acagaggagacacgtagcatccgcctcttctctgatgactccaaacgccacactttgcca ggcgtgggactgagcacgtcactgagccctcggtttaacttcacacctccatgcttcata acgactaagcgtgagcacatctacagtccacagattccgctaggtattctaaaggagaag gccatcagcatgctgacggaggcagtgcaaggtggaggtgctcatattcgtgaccctgta gggggcagcgtagagtaccaatttgtgcctatactcaagctgattgcgactctgttgatt atgggctctctgagtagtgaggaggtgagaatcatcctcctgcttatcgaacccaatgtt ttcggagaaatcaaggaggaggagacacaacttttagctgtagaggagccagcagaaaaa gaagaggcaagcagcaatgaggaaaaagccgtggaggctggggaggaagaaagcaaagaa cataagcagccacctaaaggccttttggagaagagcctgcctgagtcagttaaacaccag atgtgtgaactcctgcactatttctgtgattgtgagctgaagcagcgcatcgagtctatt gtggcattctcagatattttcgtggccaaactgcagttcaaccagaagttccgctacaat gaactcatgcaggccctcaacatgtccgctgctgttactgccaagaagacgaaggaattc cgctcacctccccaagagcagattaacatgcttctggacttcagtgctggagaggattgt ccctgtcctgaggacattcaagaagagcttcatgccttccatgatgatctgagactccac tgtggtattcccatggaagaagaagaggaggaaccggatacatctataaaaggccgcctg ctctccttgttatataaaatcaaaggtcgcccacagaaaactgaggaacaaccatcagag gaagagcaagcagctccaacaaacctgaaggagctgatctctcagacaatggtgagctgg gcccaggaatgcaaaattcagaacccaaagctggtacgaagcatgttcagcctactccga aggcaatatgatggcattggtgagctgctgcgtgccatgagaaaaagctatactatcagt gagaaatctgttcaggatgccattaacctactggcctcactgggccagatccgctctctg ctcagcgtcagaatgggtgaagaggagggtcagctcatgatcgatggcctgggggatata atgaacaacaaagtgttttatcagcatccaaatctgatgcggataatgggcatgcatgag acagtcatggaggtcatggtcaacgtgctaggaggagacaaatctaaggagattgctttc cccaaaatggtggccagttgctgccgtttcctttgctacttctgtcgcatcagccgtgag aatcagaaagccatgtttgaacacttgagctacctactggagaatagcagtgtggggctg gcttgcactgccatgagaggctccactcctttggatgtggccgcatcctcagtgatggac aacaacagcctggcactggctttagaggaaccagacctggaaaaggtggtgatgtacttg gctggttgtggtctacagagctgccctatgctggtagctaagggataccctgacatcggc tggaatcctatagaaggggaacgttatctgtctttcctccgatttgctgtgtttgttaat ggtgagagtgtagaggagaatgctaatgtagtggtaaagttgttgatcaggcgtcctgag tgttttggccctgcactgagaggagaggggggacaaggtctgttggctgccatgctggag gccatcaagatctccgaggaccctgctctcgaccttcctaaccttcctggaggaggagca cctgtgcctggggaggatggggaggaggaagagttggcacacatgggcaactctatcatg tccttctactcagctcttattgacctgctgggacgctgtgcacctgagatgcatttaatc aatacaggcaagggtgaagctctgcgtatccgtgccatcctgcgttctctagtgcctact aaagacttagtgggcatcatcagcataccactgaaagtgccaataatcaacaaagatggc agtgtcacagagccagacatgaactctagtttctgtccggagcacaaatcaccaatggtg ctcttcctggaccgtgtgtatggtattgaggaccaaagcttcttgctaaacctgttggag gtgggcttcctgcctgacttcagggtctctgcatctttggacacagaggtgctgagcact acagagacagcactggccttgaacaggtatattggttcagctgtgctgcctttgctgaca cgatgtgcgtctctctttgctcatactgagcactacactacgctcatggactccacacta caaaccatttacagactgtccaagggccgctctctcaccaaggctcagagagactctatc gaggagtgccttcttgccatctgcaaacacctgcggccttctatgctgcaacagctcctg cgccgtctggtgttcgatgtgccacagcttacagaatactgcaagatgcccataaagctt ttgtccaatcactatgaacagaactggaaatactactgcctgccttcgggcctgggcagt tatgggatggcatcagaagaggagctccaccttaccaccaaactcttctggggtcttttt gatgctctctctcaaaagaaatatgatgcagagcttttcaaaatggctatgatgtgtctg agtgccataggtggagccatcccacctgattatgtatacatcagcccagccaccactctt gtaaagcaggtctctgtggattctcaaggaaactttgatcccaagcctatcaacactgcc aacatctcactgcctgaaaaacttgattacattgccaacaagtatgctgaacattgccat gagaaatggtcttctgagaagtttgctctaggctggactgcaggtgaaaaagtagatgac caagccaaaacccaccctttactgaagccatataaagcactgagtgaaaaggagagggaa acctaccgctacccagtgaaggaatctctgaagtgcatgctggcaatgggctggaccatc gaaaggaccaaagaaggagatgccatgttccaacagcgtgaagcagagaaacagattaag acttcagagccttctcagggagacggatttcatccagcgcctgtagaattggaaaatgta actttatctagagaactacagagtatggtagagactgtagcagagaattaccacaatatc tgggcaaataaaaagaaaatggaactaagcagcaaaggaggagggactcacccactgctg gtaccttacgacacactgacagcaaaggagaagttcagagacagagaaaagtctcaggag ctcttcaaattcctgcagcttaacggctatgcaataagcagaggtttgaaggaattggag catgattcttcctctatggaaaagaggattgcttacaagttcctgaagaggctgctgagt tacgtagactcagcacaggaatttatagcccatctagaggctatggccaccagtggaaaa actgacaaatcacctcatgagcaggagataaagttctttgcaaaggtcctgctgccgttg cttgaccagtactttaagaatcattgcctttacttcctgtcttctcccagcatcaatctg agcagcagcggttatgcttcaaacaaagagaaggagatgatcaccagtctcttctgtaag ctggcatctctcgttagacataggatttctctgtttggaagtgactctgctacgatggtg agctgtctgcttatccttgcacattcactggactttaggacagtgatgaagtctggttcc gaattggtgaaggctggagttaggacgttctttgagaatgctgcagaagacttggagaag actatggagaacctaaagctgggcaagatgggccagtctcgcacccaaatgaagggagtg gctcagatcatcaactacacttcagtggcactgctgcctattcttactgctctatttcag cacatcactgagcaccagtttggggcagacttgctgttggatgatgttcaactttcctgc tatcgaattctgaccagcctatactccctgggaactggcaaaaacatctatgttgaaaag cagcttccagtgctgggagaatgcttggctactctggtgggagctatgcctgtagctttc ctagagcctcatctgaacatgcacaacccacgctctgtcttcaatacaaagacaccacgg gagagagcaattctgagcatgcctgacactgtggaggagatgtgtcctgagatgccacgt gtggacggcctgttgaaagatatccacgacatctcggagtctggggctcgctacacagag atgccacatgtcatcgaggtcatcttgcccatgctgtgtaactatctttcttactggtgg gaaaagggtcctgagaactctccgaatcatgagagctgctgtaccactgtcacctctgag cacctcagcctcatcctgggtgacatcctcaagatcctcaacaacaacctgggtatagat gaagcgtcctggatgaagaggcttgcagtgtacacacagccaatcattagcaaagcagga gcagacctattacgtactcacttcctgcccaccctggagaagctgaagaagaagacagtg aagattgtggctgaggaggagatgataagggctgaaagcaaagctgacactcaggaggcc gagctgcagatcctggatgagtttgctgtcctctgcagagacctgtacgctttttacccc atgctcatccgctacgtggacaacaacaggtctaaatggctaaagaaaccaagtacagat tcaacagaactcttcaacatggtggcagagattttcatactctggtgtaaatctcataat ttcaaaagggaagagcaaaactttgtggtgcaaaatgaaatcaacaaccttgccttcctc actggagacaacaagaccaagatgtcaaagtcaggaggtcaggaccaggagaggaaaggg aagaagagaagaggagaattgtattctattcagacatccttaattgtggcagctcacaag aaactgctgccaatcggcctcaacatgtgcacggctggagaccaggagctcatctctctg gccaagatccgctacagtctgaaagacacagatgacgaggtgaaggatcatcttagacag aacctacatcttcaacagaagacagaggatccggcagtgcagtggcagctaaacctctat aaggatgtggaggtgaagggcgaggagcctataaatactgaccacattatcgcaaagatc caaggcatctcagccgccgtcttccatcttgagcaggtggagcagcctctcaggtgtaaa aaattggtatggcagaagcatctgtccaaacagcgcaagcgtgctgtggttgcctgtttc cgcatggcccctttgtacaacctccctaggcatcgctctattaacctcttcctcacgggc tatcagaaactttggatagtagcagagaagtactcctttgaggagaagctagtgcaggac ctggcaaaaacccccatggctgtcgaaaaagaagaggaggaagcagaggctgaggtccag ccagatcctcttaaccagctcatcctccacttcagtcataatgccctgactgagagaagt gtccaagaagtagatcccttgtatattgcatatgcagatatgatggcaaagagctgtgct gaggatgaagaagcagaggaggaagaagaaaaagaaaagacatttgaggagaaggagatg gagaagcagaaaattttgtatcagcaggccaggctgcatgctcgaggtgcggctgagatg gtactccagatgattagtgcaagcaaaggccatcttggccctatggtgaggtatactctg aaactgggtatctctattctcaatggaggcaatgtagttgttcagcagaaaatgctggac tacctgaaagaaaaaagagatgctggcttttttaaaagtctgtctggactgatgctgtcc tgcagtgtgctggatctgaacgcatttgagagacagaagaaggcagagagccttggaatg gtgactgaagaaggttcaatcaacgcgagtgagcggggttccaaagtactacaaaatgat gaatttacaaaggatttatttcggtttttgcagctgttatgtgagggccacaataatgat ttccaaaacttcctgcgaactcaaagtggaaatacaaccacagtcaacatcattattagc acagtggactacctcctacgtttgcaggaatccataagtgatttctactggtattactct ggaaaagatgtcattgatgagcatggacagctaaacttctccaaagccatggaagtagcg aaacagatcttcaattcactcactgagtacattcagggtccatgtattggtaaccagcag agtctggcacacagtaggctgtgggatgccgtggttggattcctgcatgtttttgccaac atgcaaatgaaactatcacaggactctagccagattgagctgttaaaggaattaatggat ttgcagaaggatatggtggtcatgatgttatctcttttggagggtaacgtggtgaatggc acaattgggaagcagatggtcgacacattagtggagtcctcaagtaacgttgaaatgatc ctcaaattctttgatatgtttctcaagctaaacaatcttactacctctgataactttaaa gagtacgaccctgaagggaaaggaattatttctaaaaaggagttccagaagtcaatggag agtcaaaagcagtacacacaatctgagattgattatcttctctcttgtgctgaggctgat gaaaacgacatgtttaactacatggaatttgtggaacgcttccacgagccggcaaaggat attggcttcaatgtggctgtgctgctcaccaatctgtccgagcatatgccccacgattca cgcctcagcaccttcctggacctggcagagagtgtactgagttatttcgagccctatttg ggccgtatcgagatcatgggcggtgccaagcggatcgagcgtatctactttgaaatcagt gaatctagcagagagcagtgggagaagcctcaggtgaaggagtccaagaggcagttcatc tttgacatggtcaatgagggcagtgaaagtgagaagatggagctgtttgtaaacttctgt gaagacacaatttttgagatgcagctggcttcccagatatccgagtcaggtgctgtagaa cgccctgaagaggaggaagaacagcatagtatgttggaggatctgtcagaagaggaagat cagtcccttgagtctgcttcagccttcactgttgcctgtgcttctgtgaagaaaaaagta tccaacttccgtcaaatgctgaccatcaagaacatgcgtaaacagttcaagaagtttaaa aagctgactattaaggaaatgattacagggttcttttcattcttttggatgcttttcaca gggttctttaaaggcatttttagcctgatctttggattctttcatataatctggtcctca atgtttggaggaggccttgttgaaggagctaaaaacatgaaggtaacagacatcttaggc aacatgccagatcctactcagtttggaatccatggcgatattatggagttagagaaagca gagaatggtgaaatagtggtatctacagaaatggtacagatggctggcacagtggacaaa ctggaacctgatgccatcatagatctcattagtccaccaactaaacgagagggaaagcat ggacatgagcctggacttggggatgtctcagagattaccacagaagccagtcctcgcgtt gaaaagaaaaagtgccagaaagctgtaccagaggagcctgaacctgagaaagctgacaca gagactcatgaaaaagaagataaagccaaagaggaaaagcctgaagagccagtagcggag gagatgctagcgccaagaaaacaccatggcccacccaaggaggaacctcctgaattaatg gccaccttctttgctggccttgaagtgtataagaccaagatgctaaactacttggctcgt aatttttacaaccttcggatgttggcgctttttgtggcatttgcaattaacttcatcctg ctcttctacaaggtgactgctgaaacagaggatgaggatgaggaggagtcatggggtggc agtgatgatgatgatgaagaagacagtgatatggaattctatgtactccaggagggcact ggctatatggctcccactctgactttcttggctatactgcatacagttatttctctcctt tgtgtggtgggatattactgcctcaaggtccctttggtggtgtttaagcgagagaaggag attgcaaggaagctcgagtttgatggattgtacatcaccgaacagccatctgatgatgat atcaagggacaatgggatcgtttggttattgccactccgtctttccccaataattactgg gacaaatttgtcaagaggaaggtcatcaacaaatacggagatttgtatggagctgagcgt attgctgaactcctcggactggataagagtgcactcgactttgatcctacagaggaagct gtggtgaaagaggcttctctgttatcctggttgagctctatagacacgaagtaccacatt tggaaaatgggagttgtcctaactgacaattcttacctctacctgatctggtacaccacc atgtctgttctgggccattacaacaacttcttctttgctgctcatttgctggatattgcc atgggcttcaagactttgagaacaatcctgtcttctgtaactcacaacggcaaacagttg gtgttgactgtgggcctgcttgcagttgtggtttatctgtacactgttgtggcgttcaac ttcttccgcaagttctacaacaagagcgaggatgaggatgaacctgacatgaaatgtgat gatatgatgacttgctacctattccacatgtacgttggtgtgagagctggtggaggcatt ggtgatgagattgaagacccagctggtgacccttatgagctttaccgcatcctctttgac attaccttcttcttctttgtcattgtcatcctgttggccatcattcagggtttgatcatc gatgcatttggcgagttgagagatcagcaggaacaagtgaaggaggacatggagacaaag tgttttatatgtgggattggaaatgactactttgacactacaccacatggctttgagact catactttacaagagcacaacctggccaattatctattcttcttgatgtatctcattaat aaagatgaaactgaacatactggtcaggagtcctatgtatggaagatgtatcaggagagg tgctgggacttcttccctgctggagactgtttccgcaaacaatacgaggaccagttgggc tag

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