Tachysurus vachellii: 132852817 Help Entry 132852817         CDS       T09596                                  Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism tvc  Tachysurus vachellii Pathway tvc04020   Calcium signaling pathway tvc04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:tvc00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     132852817    04020 Calcium signaling pathway     132852817  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:tvc04040]     132852817 Ion channels [BR:tvc04040]  Voltage-gated cation channels   Ryanodine receptor    132852817 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 Motif Other DBs NCBI-GeneID:  132852817 NCBI-ProteinID:  XP_060736247 LinkDB All DBs Position 10:21222647..21400021 Genome browser AA seq 4869 aa AA seqDB search MAEGGEAEDEIQFLRTDDEVVLQCVACIQKENRKFCLSAEGLGNRLCYLELTSEAKYVPP DLCICNFVLEQSLSVRALQEMLAKSGENNETAHGGGHRTLLYGHAILLRHSFSGMYLTCL KTSRSLTDKLSFDVGLQLDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLH LSISNGNIQVDASFMQTLWNVHPTCSGSSVEEGYLLGGHVMRLFHGHDEVLTIPGSDQSE EQQRIVNYETGKVGAKARSLWRLEPLRISWCGSHIRWGQPFRLRHLTTGHYLALTEDKGL VLQDREKSDTASTAFCFRASKEKLEWSPKKDIEGMGVPEIKYGDSLCFIMHMATSLWLSY QAPDVKSTRLGPLKRRACLHAEGHMDDGFTLQRCQHEESRAARIIRNSTRLFSHFIRDLD NLAGKNRTDVVLPVDEVLQTLNDLITYFQLPDAELEHEEKQIKLRSLKNRQNLFKQEGML TLVSNCIDRLSVYNSAAHFGECVGEEAGAAWKDILNLLYELLAALIRGNRNNCTQFSQNL DWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHKILDVLC SLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVREGSAQYKKWYF ELMIDQVEHFVTSEPSHLRVGWASSKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSG RIPRRVASVNQHILTSDDVVSCCLDLGAPSISFRINGQPVQGMFESFNTDGLFFPVVSFS AGVKVRFLLGGRHGEFKFLPPSGYAPCYEALLPKERMRVEPVKEYKRDADGVRDLLGTTQ FLSQASFIPTPVDTTQIVMPPHLEKVRDRLAENIHELWAINKIELGWTYGKIRDDNKRQH PCLVDFSKLPETERNYNLQMSTETLKTLLALGCHVVQFNVNAEEELKKVKLPKNYMMSNG YKPMPLELSEVKLSPAQELLVDKLAENAHNVWAKDRVKQGWTYGIQQDLKSKRNPRLVPY ALLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQEGGCVVERLSIDKIRFFRLERTYAVK TGKWYFEFEIVTGGDMRVGWARPGVRPDVELGTDDQAFVFDGYKGHRLHQGSRLFGRCWH AGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFIPVCSLGLSQVGRMNL GKDASTFKYYTMCGLQEGFQPFAVNMNREVTMWFSKRLPTFVNVPKDHSHIAVIRIDGTI DSPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFHSTYKNFPVTEMNGVHEEEPLKLKYRY PVKSTKHVDEGRRTDYSNITTYSHSVRVFAGQDPSCVWVGWVTPDFHYYSNFFNLSKIRT VTVTLGDERGRVHESVKRSNCYIVWGGDAISSSHSSSRSNVDLEIGCLIDLATGLVSFTV NGRELPTSYQVEPNTKLFPAVFVRPTSSNLFQFELTKIKNAMPLSSAIFKSEHKNPIPQC PPRLDIQTIKSVLWSRMPNTFLKVDTARVSERHGWQVQCLEPLQMLAVHIPEENRCVDIM ELSEQEDLRTFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYIIDNQYLSGMLRQGF YDVLISIHLETAKAAQLMMNNEFIIPITAETRSIRLFLDSSKRHQPPGVGLSTSLKPRLS FAPPCFITPKRDQYLYSPAIPLDVLREKAISMLTEAVQGGGDHIRDPVGGSVEYQFVPIL RLISTMLTMGVLTSQDVHKILLLIELHVFGEQKADEMGEATEKEGMTGAEEKAVEAGEEE AKDRKQPMKGLLEKKLPESVKLQMCKLLQYFCDCELRHRIEAIVSFSDSFASKLQFNQKF RYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLNFSMGEDCPCPEDIREELYEFHSEL CLHCGIPMEEEEEDQDTSFKGRLMALVNKIKGQRHKAEEKPKEKEQAIPSNLKELISQTM VSWAQESHIQDPELVRAMFSLLRRQYDSIGELLRAMRKSYTISAASVHDTIHLLASLGQI RSLLSVRMGKEEEQLMIDGLSDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGGKSQE IAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDVAASS VMDNNSLALALEEPDLNKVVTYLAGCGLQSCPMLLAKGYPDIGWNPIEGERYLSFLRFAV FVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETPALDLPSTTQ GRISDTSTEDEEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRS LVPTEDLVGIISIPLRMPVVNKDGSVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLL HLLEVGFLPDLREAASLDTEALRTTETALAMNRYIGSAMLPLLTRCAPHFAGTEHHVTLI DSTLHTIYQLSKGSSLTKAQRDAIEECLLAVCKYLRPSMLQQLLRRLVFDVPLLSEYCKM PLKLLTNHYEQNWKYYCLPSGWGSYGMASEEELLLTKKIFWGIFDSLSQKKYEQELFKMA MPCLSAIAGALPPDYVDSSLSTTLEKPVFVDAQGNFDPRPINTAIISLPEKLEYITHKYA EHSHDKWSAEKVVLGWKYGDNVDEKAKTHPMLRSYKSLTEKEKDIYRFPVKESLKSMLAM GWSIDRTKEGEAMFQQRENEKMRKISQASQGSGFHPSPVDMSNVLLSRELQAMVEVLAEN YHNIWAKKKKSDLAVKGGTHSLLVPYDTLTAKEKARDREKAQDLFRFLQINGYAITRGLK DMEQDSSSMEKRFAYKFLKKLLKYVDCAQEYIAHLEAMASSGKNDRSPHEREIKFFAKVL LPLIDQYFKNHSLYFLSSPSKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFGSDSA TMVSCLHILAHTLDTRTVMKSGSELVKAALRTFFENAADDLEKTLENLKLGKFTHSRSQM KGVSQNINYTTVALLPILTALFEHITEHQFGADLLLDDVQVSCYRILSSLYSLGTGKNIY VERQLPALGECLATLAGAMPVAFLEPHLNTHNPFSVFNTKTARERAILGMPDTVEQMCPE VPHLDCLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLSYWWERGTENQAKGTTTACST TVTSEHLSIILGNILKILNSNLGIDEASWMKRIAVYAQPIISKARADLLKTHFLPTLEKL KKKTVKVVAEEELLKADNKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWQK EPDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDSKTKISKAGGQD QERKHKKRRGEGYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYGLKDTDEEVK EHLRRNMHLQERSEDPAVRWQLHLYKDVIVKNEGPPDPERTIDRIQTISAAVFHLEQVEQ PLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLTGYQRIWIETETYSFEE NLVQDLARTQRKVEEEEEEIDEIQPDPLHQLILHFSHNALTERSSLEDDLLYIAYTDMMA KSCAEDENEDEEGKEKTFEEKEMEKQKMLYQQARLHDRGAAEMVLQMISASRGRLGPMVT STLKLGISILNGGNILVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEG LGMVTEEGSSSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIISTVD YLLRLQESISDFYWYYSGKDVMDEAGQRNFSKALNVAKQIFNSLTEYIQGPCIGNQQSLA HSRLWDAVVGFLHVFANMQMKLSQDSSQIKLLKELMDLQKDMIVMMLSLLEGNVVNGTIG KQMVDTLVESSNNVEMILKFFDMFLKLKDLTTSDSFKEHDSDGKGVISKREFQKSMENQK QYSQSEIEFLLSCVEADENDMFNYVEFVKRFHEPAKDIGFNVAVLLTNLSEHMPHDSRLA TFLNLAESVLNYFEAFLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDV VNEGGESEKMELFVNFCEDTIFEMQLASLISEPDTVERGEEDEDEMHNVIKDLEVEEEEN TLESSSAFTMACVSMKKNLCSLGRLLTLKSLRKHYKKFRKMSLREMISGFFSFFWMIFTG LLRFFYNLVWCFFHILWSTLFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDVLETEKLE VSEASLVADVDQMAQGDKTEMDLMSELLSIQPKKEGGKHGAEPGLGDVSEVVGVDSPSLV TAVQQKKAQEAASKQSVENELNAESEKADTEDGEKNDQVKSKELLIEPSSEEERKPSKRR CGRKKEQPEVIMASFFAGLEIYQTKILNYLARNFYNLRFLALFVAFAINFILLFYKVTGE ESEEVDSWTGRNEDEDESAIEYFILQENTGYMAPTLRFLAVLHTIISFLCVVGYYYLKVP LVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFIKRKVINK YGDLYGAERIAELLGLDKSALDFNPTEETIAKEASLVFWLSFIDTKYHIWKMGVVFTDNS FLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVV YLYTVVAFNFFRKFYNKSENEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDP YELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNEYF DTTPHGFETHTLQEHNLANYLFFLMYLVNKDETEHTGQESYVWKMYQERCWDFFPAGDCF RKQYEDQLG NT seq 14610 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggcggagaagcggaagacgagatccagttcttacggacggatgatgaggtg gtgttgcagtgtgtggcctgcattcagaaggagaatcgcaagttctgtctgtctgctgag ggacttggcaatcggctttgctacttggaactcacctcagaggccaagtatgtccctcca gatctgtgcatttgtaactttgtgctggaacagtcactgtctgttcgggccctgcaggag atgctggctaaaagcggggagaataatgaaacagcacatggaggtggacacagaacacta ctgtatggacacgccatcctcctgcggcactctttcagtggaatgtatctgacatgttta aagacatccaggtccctgacagataagttgtcttttgatgttggtcttcagttggactcg acaggtgaagcttgttggtggactattcatcctgcttctaagcagagatcagagggggag aaagttcgtattggtgatgacctcattctcgtcagtgtatcatctgagcgctatctacac ctttccatctccaatggtaacatccaggtggatgcatctttcatgcagactctgtggaat gtccatccaacctgttctggcagcagtgtggaggaaggatatctccttggtggtcatgtg atgcgtttgtttcatggacatgatgaggttttgacgatcccgggctcagatcagagtgag gaacagcagagaatagtcaactatgaaacaggcaaagtaggggccaaggccagatctctt tggagattggaacctctacggatcagttggtgcggcagtcatatccgctggggacagcca tttcgcctgcgccacctcaccacaggtcattatctggccctgactgaagacaaaggcctt gtgctgcaggatcgggagaaatcagacacagcctccaccgccttctgcttccgagcatcc aaggagaagctggagtggagtccaaagaaagatattgagggcatgggggtgcctgagatt aagtatggggactcgctctgtttcatcatgcacatggccactagcctgtggctctcgtac caggcaccggatgtaaaatcaacacgactggggcctctcaagagacgggcatgtctccat gcagaaggacacatggatgatggcttcacgcttcagcgctgtcagcacgaagaatcacgt gcagcacgcatcatccgcaacagcaccagactcttcagccatttcatcagagacctggac aatctggctggaaagaatcgaacagatgtcgttcttcccgtcgatgaggttctccagacc ctaaatgacctcattacatattttcaactccctgatgctgaactggagcatgaagagaag cagatcaaactgcgctcactcaagaaccgtcaaaatctcttcaaacaggaggggatgctg acattggtgtctaactgcattgatcgtttgagtgtctataacagcgcagcacactttggg gaatgtgttggagaggaagctggtgcagcttggaaagacattctcaacctgctctatgag ctccttgccgctttgatccgaggaaacagaaataactgcacacaattctctcaaaacctg gactggctggtcagcaagctggagagactggagtcctcctcagggatcctggaggtcctt cactgcatcttaatcgaaagcccagaggcgcttaacatcattcagagaggacatatcaaa tccatcatctcactgctatacaaacatggacgcaaccacaagatcctagatgttctgtgc tcactctgcgtttgtaacggcgtagctgtaagagccaatcagaacctcatctgcgatcac ctgctcccaaaacgagacctgttactccagacacggcttgtcaatgatgtccaaagcatg agacctaacatctttctgggagtgagagaaggttcagctcagtacaagaagtggtacttt gagctgatgatagaccaggtagagcactttgtaaccagcgaaccttctcacctgcgagtc gggtgggcttcctccaaaggctatgccccctacccagggggtggagagggctgggggggt aacggagttggagatgacctctattcttatggctttgatggacttcacttgtggtcaggt cgaatcccacggagagtagcttcagtaaaccagcacatacttacctcagatgacgtagtc agctgctgtttggatcttggagcgccaagcatctcctttagaatcaacgggcagcctgta caaggcatgtttgagagcttcaacacagacggtctcttcttccctgttgtcagcttctcc gctggggtcaaggtgcgcttccttttaggtggtcgccatggtgaattcaagttccttccc ccatcaggctatgctccctgctatgaggcactgcttcctaaagaaaggatgcgagtagaa ccagtaaaggagtacaaaagggatgcggatggagttagagatttgctgggcaccacacaa tttctgtcacaggcttcttttatacccacaccagtggacaccactcagattgtcatgcct cctcacctggaaaaagtacgtgacaggctggctgagaacatccatgaactatgggccatt aacaagattgaacttggctggacttatggcaagataagggatgataataaaaggcagcac ccgtgcctggtggatttctcaaagctgcctgaaacagagaggaattacaacctgcagatg tcaacagagacgttaaagactcttttggctctgggctgccatgtggttcagttcaatgtc aacgctgaggaggagctgaaaaaagtgaaactcccaaagaactacatgatgtctaatggc tataagcccatgccactggagctttcagaagtgaaactgagccctgcacaggagctgctt gttgacaagttggctgagaatgcacacaacgtttgggccaaagatcgggttaaacagggc tggacctatggcatacagcaggatttgaaaagtaagcgcaatccccgtcttgtgccgtat gcattgcttgatgagcgcaccaagaagtcgaaccgtgacagcctgcgtgaagccatccgt acactaattggctacggctataacatcgagcctcctgaccaggaggggggttgtgtggtg gagagactaagcatcgataagattcgttttttccgtttggagaggacatatgcagtgaaa acagggaagtggtattttgagtttgagatagtgaccggaggagatatgagagtcggttgg gctcggccaggcgtgcggcctgatgtggaactgggaacagatgatcaggccttcgtcttt gatggatataagggtcatcgtctccaccagggcagccgcttgtttggtcgttgttggcat gctggggatgtggtgggctgcatgattaacatggaggacaagtccatgatcttcacactt aacggagaaatcctcattacaaacaagggctcagaactttgctttgctgactttgagact gaggatggatttattccagtctgtagtctgggcctttcccaagttggacgtatgaacctg ggcaaagatgccagcaccttcaaatattataccatgtgtggcctgcaagaaggatttcag ccctttgctgtcaacatgaatcgggaagtcactatgtggtttagcaagcgccttcctaca tttgtcaatgttcccaaagatcatagtcatattgcggtcataaggattgatggcactatt gacagccccccatgtctcaaagtgactcacaagacatttgggacacagaacagcaatgcg gacatggtgttctgccgtctgagcatgcctgtcgagttccactccacctacaagaatttc cctgtcactgaaatgaatggagtgcatgaagaagagccactgaaactcaaatataggtat cctgtaaaatctacgaaacacgtagatgaagggaggagaactgactatagtaacataaca acttactcccattcagtacgagtgtttgctggccaagatccctcgtgtgtgtgggtcggc tgggtcacacctgacttccattactacagcaacttctttaatctcagcaaaatccgaacg gtgacagtaacattaggggacgaacgaggtcgggtccatgaaagtgtgaaaaggagtaac tgctacattgtctggggaggtgatgccattagctccagccactcgtccagcagaagtaat gtggatttggagattggttgcctcattgatttggctactggcttagtgtcctttactgtc aatggcagagaacttccaacctcatatcaggtggagccaaatacaaagcttttccctgct gtgtttgtacgtcctaccagttcaaatctgttccagtttgaattgacaaagataaagaat gctatgcccctttcatcagcaatttttaagagtgaacacaagaacccgatccctcagtgt cctcctcgtctggatatccagaccattaaatcggttctgtggagccggatgcccaacacc tttctgaaggtggacacagctcgagtgagtgaaagacatggatggcaggtccaatgtctg gagccactgcagatgttggcagtacacattccagaggaaaaccggtgtgtggacataatg gaactctctgagcaggaagacctgcggacattccattatcacactttaaagctttactgt gcactctgtgcccttggtaacacccgtgtagcacatgctctctgcagccaccttgaccag tcacagctcctttacattattgacaaccaatacctgtctggcatgctgcgccaaggcttc tatgatgtcctcatcagtattcacttagagacagccaaagctgcccaacttatgatgaac aatgagtttatcatcccaataacggcagagactcgcagcatacgactctttctagattct tccaagagacaccagccacctggtgttggacttagtacatctctaaaacccagacttagc tttgctccaccgtgcttcatcactccgaagcgtgatcagtatctctacagcccagcaatt ccattagatgttctaagggagaaggcaattagcatgctaacagaggctgttcagggtgga ggagaccacattcgagatcctgtaggtggcagtgtggagtatcagtttgtgccgattctc cggctgattagcacaatgctaaccatgggtgtgctaacaagccaggatgttcataagatc ttgctgctcattgaactgcatgtctttggggagcagaaagcagatgaaatgggtgaagct acggagaaagagggaatgacaggagcagaagagaaagcagtggaggctggagaagaggaa gccaaagataggaagcagccaatgaagggactgctggagaagaaattgccagaatcagtc aaactgcagatgtgcaaacttctgcagtacttctgtgactgtgaattaaggcaccgtatt gaggccattgtttcgttctctgatagttttgcgtcaaagctgcagtttaaccagaagttt cgttacaatgagttaatgcttgctctcaatatgtctgctgctgttactgccaagaagact aaagagttccgctcacccccacaagaacagatcaacatgctgttaaatttcagtatgggt gaggactgtccatgtcctgaggacattagggaggaactctatgaattccacagtgaactt tgtctacactgcggtattccgatggaagaggaggaagaggatcaggacacgtctttcaaa ggccgtctgatggctctagttaacaagatcaaggggcagcggcataaagcagaagagaag ccaaaagagaaagagcaagccattccttcaaatctcaaggagttgatctctcagaccatg gtaagctgggctcaggagagccacattcaagacccagagctggtgcgtgccatgttcagc ctactgcggagacaatatgacagcattggcgagctgctgcgtgctatgcgcaaaagctac accattagtgctgcatctgtgcacgacaccattcacctgctggcctcactgggtcagatc cgctcattgctcagcgtccgtatgggcaaagaggaagagcagctcatgattgatggcctc agtgacataatgaacaataaggtgttctaccagcacccgaacctgatgagagtactgggc atgcatgagaccgtcatggaagttatggtgaatgtgctggggggaggcaagtctcaggaa attgcttttcccaaaatggtggctagttgctgccgctttctgtgctatttctgtcgaatc agccgacagaaccagaaggccatgtttgatcatttgagttacctgctagagaacagcagt gtgggtttggcttctccatcaatgagaggatccactcctctagatgtagctgcttcttct gtaatggacaacaacagccttgcactcgctcttgaggaaccagacctcaacaaggtggta acatatctggctggctgtggactccagagttgtcccatgctccttgccaaaggctatcca gatattgggtggaacccaatcgagggagagcgctatctctcctttctccgctttgctgtc tttgtcaacggtgagagtgtagaagagaattccagtgttgtggtgaagttgctgattcgt cgacctgagtgctttggccctgcgttgcgtggagaaggcggtaatggactgctagctgcc atgaaggaagccattaaaatatcagaaacgccagcactagacctgcccagcaccacccag ggccgaatctctgacacgtctacagaggatgaggaggaggaagaagtggttcacatgggc aacgccatcatgtccttctactcagctctcattgatctgttgggacgctgtgcacctgaa atgcatctcatcaataagggcaaaggagaggctctgagaatccgtgccatcttgcgctcc ttggtgcccactgaagaccttgttggcatcatcagcatcccactcagaatgcctgtagtc aataaagatggtagcgtgacagagccggacatgtcagcttgtttttgcccggaccacaag gcgcccatggttctgtttctggaccgggtctatggcatagaagaccaaagcttccttctt catcttctggaagtcggcttcctgcctgacctaagagaggctgcatctctggacacagaa gcattacggaccacagaaacagcactggccatgaaccggtatatcggatctgcaatgctg cccttgctgactcgttgtgccccgcattttgccggcacagaacaccacgtcacactaatt gactccacgctccacaccatctaccagctgagcaagggctcgtcactcactaaagcccag agagatgctatcgaggagtgcctgctggccgtatgcaagtacttaaggccatctatgctt caacagctgctgcgtcgcttggtgtttgacgtgcctctgctgtctgaatattgtaagatg cctcttaagctgttgaccaaccattatgagcagaactggaagtattactgcctgccttct ggttggggcagctatggcatggcctctgaggaggaattactactaaccaagaagattttt tggggcatctttgactcgctttctcaaaaaaagtatgagcaggagctgtttaagatggct atgccatgtctgagtgctatagctggagctttgcctccggattatgttgattcttctctc agcaccacactggagaagccggtctttgtggatgcccagggcaactttgaccccagaccc atcaacacagcaatcatctccctcccagagaagctggaatacatcactcacaaatacgct gagcattcccatgataaatggtctgctgagaaggttgttttgggctggaagtatggagat aacgttgacgagaaagcaaaaacacaccccatgctgagatcctacaagtcactcacagag aaggaaaaggacatttaccgcttcccagtgaaggagtctttgaagagtatgctagccatg ggctggagcattgaccggaccaaagagggagaggccatgtttcagcaaagagagaacgag aagatgcgcaaaatttcccaagcatctcagggtagtggctttcacccaagtccagtagac atgagcaacgtattgctctctcgtgaactgcaggctatggtagaggtgttggctgaaaac taccacaacatttgggcaaaaaagaagaagagtgacttagcagtaaaaggtggaacacat tctttgttggtgccatatgatacacttacggccaaagagaaggccagagatcgtgagaaa gcacaggacctgttccgcttcctgcagatcaacggctatgccattaccaggggtttgaaa gacatggaacaggactcatcctccatggagaaaaggtttgcctataaattcctgaaaaag ctgctaaaatatgtggactgtgcacaggagtacattgctcatctggaggctatggctagc agtggaaagaatgaccggtcacctcatgagcgggaaatcaagttttttgccaaggtgctt ctaccactaatagatcagtacttcaagaaccattctctctacttcctctcctcccccagt aagaacctcagcagcagtgggtatgcttcaaacaaagagaaagagatggttaccagtctt ttctgtaagctggcagctcttgttagacacaggatctctctgtttggaagtgattccgcc actatggttagctgtcttcatatcctggcccacacacttgacactagaacggtgatgaag tctggttctgagttggtgaaagctgccttgaggacattctttgagaatgcagcagatgac ctggagaaaacgctagagaacttgaagctagggaagttcacacactcacgcagccagatg aagggtgtgtcacagaacatcaactacaccacagttgccctgttgcccatccttactgcc ttgtttgagcacatcactgagcatcagtttggagctgaccttttattggacgatgtccag gtctcatgctatcggatcctgagcagtctctactctttggggactgggaagaacatctat gttgaaagacagcttccagctcttggtgagtgtttggccaccctggcaggagcgatgcct gtggcatttttggagcctcacctcaacacacacaaccctttctctgtcttcaacacaaaa acagcacgggaacgtgccattttaggcatgcccgacacagtagaacagatgtgcccagaa gtgccgcatctcgactgcctgatgaaagacatcaatgacatgtctgagtcaggagctcgc tacactgaaatgcctcatgtcattgaggtagtgctgcccatgctgtgtaactacttatcc tactggtgggagagaggcacagagaaccaggccaagggcacaacaactgcatgtagcacc acggtcacctctgagcacctgagcatcatcctgggcaacatcctcaagatcttgaatagc aatctgggcattgatgaggcctcctggatgaagaggattgcagtgtacgctcagcccatc atcagcaaagcgagggcagatcttttaaagacgcacttcctgccaacactggagaaatta aagaagaaaacagtgaaggtagtggcagaggaggagcttctcaaagctgacaacaaaggc gatacccaagaagcagagctactgatcctggatgagtttgcagtgctgtgccgggatctg tacgccttctatccaatgctcattcgctatgtggacaacaacaggtcacgatggcagaaa gaacctgatgctgactccaacgaacttttcaggatggtagcagaaattttcatcctttgg tgcaagtcacacaattttaagcgagaggaacagaattttgttgtgcagaatgagatcaat aatctctccttcctcactggggacagcaagacaaagatatcaaaggcaggaggtcaggat caggagagaaaacacaagaagagacgtggagagggttactctatccagacctctttgatc gtggcagctctgaaaaaaatgctacccattggcctgaacatgtgcacacctggagaccag gagctcatctcgttggctaagactcgctatggcctgaaagatacagatgaagaggtgaag gagcatttgaggaggaacatgcacctgcaagagaggtcagaggaccctgctgtaaggtgg cagctccatctgtataaagatgtgatagttaagaatgagggcccacctgatccagagcgc acaatcgatcgcattcagaccatctcagctgcagtgtttcaccttgaacaggtggagcag ccattaaggtccaagaagtgtgtgtggcaaaaactactgtccaaacagcgtaagcgtgcg gtagtggcttgtttccgtatggcaccgttatacaacctacctaggcatcgctctattaac ctgttcctcacgggctaccagagaatatggatagagacagagacgtactcatttgaggag aatctagtgcaggatttggcaaggacgcagcggaaagtagaggaggaggaagaggaaatt gatgaaatacaacctgatcctcttcatcagcttattctgcactttagtcataacgctctg actgaaaggagttccctagaagatgacttgctatatatagcatacacagacatgatggca aagagttgtgctgaagatgagaatgaggatgaagaaggaaaagaaaaaacctttgaggaa aaagaaatggaaaagcagaaaatgttgtaccagcaggccaggttacatgaccgaggggct gctgagatggttttgcagatgatcagtgccagcagaggtcgactaggccctatggtaact tccacccttaagcttggcatctccattcttaatgggggcaatattttagttcagcagaaa atgctggattatttaaaggagaagcgagatgctggtttcttcaagagtctgtcaggactc atgcagtcatgcagtgtattggacctgaatgcgtttgagaggcaaaacaaagctgaagga ttgggcatggtgactgaggagggttcaagttccaaagttctacaaaatgatgagttcact aaagatctgtttaggttcctgcagctcctctgtgagggtcacaacaacgacttccagaac tttctgaggactcagactggcaatacaactactgttaatataataataagcacagtggac tatcttcttagattacaggagtccatcagcgatttttactggtattattctgggaaagat gtaatggatgaggctggtcaacgtaatttctctaaagctttaaatgtggccaagcagatc tttaactcccttactgaatatatacagggtccgtgtataggaaaccaacagagtttggcc cacagcaggttatgggatgcagttgttggctttttgcatgtttttgccaacatgcagatg aagctctcacaggactccagccagattaagttgctgaaagaactcatggatctgcagaag gatatgatagtcatgatgctgtcccttctagaaggaaatgttgtaaatggtaccattggc aaacagatggttgacaccttggtggagtcctccaacaacgtagagatgatcctcaagttt tttgatatgttcctcaagcttaaggacctcaccacatcggacagtttcaaagagcatgac tctgatggcaaaggagtcatttccaaaagagagtttcagaaatcaatggaaaatcagaaa cagtactctcagtctgaaattgaattcctgctttcttgcgtagaggcagatgaaaatgac atgttcaattatgtggaatttgtaaaacgcttccatgaacccgccaaggacattggtttt aatgtcgcagtactgcttacaaatctgtcagaacacatgcctcatgactcccgtctggct accttcctgaacctggcggagagcgtccttaattactttgaggcgttcctgggccgtatt gagatcatgggtggtgccaagagaatagaaagggtctactttgaaatcagcgagtctagt agaacacagtgggagaaaccacaagttaaggaatctaagagacagtttatttttgatgta gtcaacgaaggtggagaatcggagaagatggagttgtttgtcaatttctgtgaggatacc atttttgagatgcagctagcttccctgatctcagagcctgatactgtggaaagaggagaa gaagatgaggatgagatgcataatgtaatcaaggatctggaggttgaagaggaggagaat acattggaatcctcctcagctttcaccatggcatgtgtctcaatgaaaaagaacctctgc agccttggaagactgctcacactaaaaagcctgaggaaacattacaagaagttcagaaaa atgagtctgagagagatgatttctgggttcttctcctttttctggatgatcttcactggt cttctacgattcttctacaacctggtgtggtgctttttccatattctttggtcaactctg tttggtggtggcctggtggaaggtgccaagaatataaaggtgacggacatccttggcaac atgccagaccccacacagtttggtatccatggtgatgtgttggagactgaaaaactggag gttagtgaggcttctttggttgctgatgtagatcagatggcacaaggagacaaaacagaa atggatctcatgtcagagctgctaagtatacagcccaagaaggagggaggaaagcatgga gctgagcctggtctgggagatgtgtctgaagtggttggagtcgattctccatctttagtt actgcagtgcagcagaaaaaggctcaggaagctgcaagtaagcagtcagttgagaatgaa ttaaatgcagaatcggaaaaagcagatacagaggatggggagaagaatgaccaagtcaag tctaaggagttgctcatagaaccgtcgtcagaggaagaaaggaagccgtccaagaggagg tgcgggcggaagaaagaacagccagaagtcattatggccagcttttttgctggtctggaa atctaccaaaccaagattctaaattacctggctcgaaacttctacaacctgcgattcctg gctctgtttgtggcatttgccatcaacttcatccttcttttctataaggtaactggggag gagtcggaggaggtggactcatggacagggagaaatgaagacgaggatgaaagtgccatt gagtattttatcctgcaggagaacactggttacatggcacctacactccgctttctagct gtcctacacactatcatctcctttctctgtgtggtggggtattactatctgaaggtgcct ttggttgtttttaagcgagagaaggaaattgccaggaaacttgaattcgatggtctttat atcactgaacagccttctgatgatgatattaaagggcaatgggacagacttgttattaac acaccatcttttcctaataattactgggataagtttatcaaacggaaggtaataaataaa tatggggacttgtacggagcagagcggatcgctgagttgcttggcctcgacaaaagcgct ctggacttcaaccctactgaggaaactattgctaaagaagcttcactggtgttctggtta agcttcattgatacaaaatatcacatctggaaaatgggtgtagtgtttacagacaattct tttctgtacctggtgtggtataccacgatgtccatcctaggccattacaacaatttcttt tttgctgctcacctgctagacattgccatgggtttcaagactttgaggactatcctttct tctgtcacccacaacggcaaacagctggtgctgactgtgggtctgctggctgtagttgtg tatctatacactgttgtggcctttaacttcttccgtaaattctacaacaagagcgagaac gaagacgaaccagacatgaagtgtgacgatatgatgacttgctatttgttccacatgtac gtgggtgtgcgtgctggtgggggaataggagatgaaattgaggatccagcaggtgacccc tatgagctttaccgcatcctctttgatatcacctttttcttctttgtcattgtcatcctt ctggccattatccaaggtttgattattgatgccttcggagaactgcgagaccagcaggag caagtcaaagaggacatggagactaaatgcttcatctgtggcattggtaatgaatacttt gacacaactccacatggctttgagacacacacattacaagagcacaacttggcaaactac ctgtttttcctgatgtacctcgtcaacaaggatgaaacagaacatactgggcaggagtcg tatgtgtggaagatgtatcaggagcgatgctgggatttctttccagctggagactgtttc aggaaacagtatgaggaccagctgggctaa

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