KEGG   Ursus arctos horribilis (North American brown bear): 113259177
Entry
113259177         CDS       T05909                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah04010  MAPK signaling pathway
uah04020  Calcium signaling pathway
uah04022  cGMP-PKG signaling pathway
uah04114  Oocyte meiosis
uah04218  Cellular senescence
uah04310  Wnt signaling pathway
uah04360  Axon guidance
uah04370  VEGF signaling pathway
uah04380  Osteoclast differentiation
uah04625  C-type lectin receptor signaling pathway
uah04650  Natural killer cell mediated cytotoxicity
uah04658  Th1 and Th2 cell differentiation
uah04659  Th17 cell differentiation
uah04660  T cell receptor signaling pathway
uah04662  B cell receptor signaling pathway
uah04720  Long-term potentiation
uah04724  Glutamatergic synapse
uah04728  Dopaminergic synapse
uah04921  Oxytocin signaling pathway
uah04922  Glucagon signaling pathway
uah04924  Renin secretion
uah05010  Alzheimer disease
uah05014  Amyotrophic lateral sclerosis
uah05020  Prion disease
uah05022  Pathways of neurodegeneration - multiple diseases
uah05031  Amphetamine addiction
uah05152  Tuberculosis
uah05163  Human cytomegalovirus infection
uah05166  Human T-cell leukemia virus 1 infection
uah05167  Kaposi sarcoma-associated herpesvirus infection
uah05170  Human immunodeficiency virus 1 infection
uah05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uah05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113259177 (PPP3CB)
   04310 Wnt signaling pathway
    113259177 (PPP3CB)
   04370 VEGF signaling pathway
    113259177 (PPP3CB)
   04020 Calcium signaling pathway
    113259177 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    113259177 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    113259177 (PPP3CB)
   04218 Cellular senescence
    113259177 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    113259177 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    113259177 (PPP3CB)
   04660 T cell receptor signaling pathway
    113259177 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    113259177 (PPP3CB)
   04659 Th17 cell differentiation
    113259177 (PPP3CB)
   04662 B cell receptor signaling pathway
    113259177 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    113259177 (PPP3CB)
   04921 Oxytocin signaling pathway
    113259177 (PPP3CB)
   04924 Renin secretion
    113259177 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    113259177 (PPP3CB)
   04728 Dopaminergic synapse
    113259177 (PPP3CB)
   04720 Long-term potentiation
    113259177 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    113259177 (PPP3CB)
   04380 Osteoclast differentiation
    113259177 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113259177 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113259177 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    113259177 (PPP3CB)
   05163 Human cytomegalovirus infection
    113259177 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    113259177 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    113259177 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113259177 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    113259177 (PPP3CB)
   05020 Prion disease
    113259177 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    113259177 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    113259177 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113259177 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:uah01009]
    113259177 (PPP3CB)
Enzymes [BR:uah01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     113259177 (PPP3CB)
Protein phosphatases and associated proteins [BR:uah01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     113259177 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 113259177
NCBI-ProteinID: XP_026360256
LinkDB
Position
Unknown
AA seq 480 aa
MDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFF
DLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHL
TEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLD
RFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLS
IIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNC
SPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEI
IRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAE
KAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1443 nt   +upstreamnt  +downstreamnt
atggatgggatacccagggttgatgttctgaagaaccacttagtaaaagaaggtcgggta
gatgaagaaattgcacttagaattatcaatgagggtgctgccatccttcggagagagaaa
accatgatagaagtagaggctccaattacagtgtgtggtgacatccatggccaatttttt
gatctgatgaaactttttgaagtaggaggatcacctgctaatacacgatacctttttctt
ggtgattatgtggacagaggttattttagtatagagtgtgtcttatatttatgggtcctg
aagattctgtacccaagcacattatttcttctgagaggcaatcatgaatgcagacacctt
actgaatattttacctttaagcaggaatgtaaaattaaatattcagaaagagtctatgaa
gcttgtatggaagcttttgatagtctgcctcttgctgcacttttaaatcaacaatttctt
tgtgttcatggtggactttcaccagaaatacacacactggatgatattaggagattagat
agattcaaagagccacctgcatttggaccaatgtgtgacttgctatggtccgatccttct
gaagattttggaaatgaaaaatcacaggaacattttagtcacaatacagttcgaggatgt
tcttatttttataactatccagcagtgtgtgaatttttgcaaaacaataatttgttatcg
attattagagctcatgaagctcaagatgcaggctatagaatgtacagaaaaagtcaaact
acagggttcccttcattaataacaattttttcggcacctaattacttagatgtctacaat
aataaagctgctgtattaaagtatgaaaataatgtgatgaatattcgacagtttaactgt
tctccacatccttactggttgcccaattttatggatgtcttcacatggtctttaccattt
gttggagaaaaagtgacagaaatgttggtaaatgttctgagtatttgctctgatgatgaa
ctgatgactgaaggtgaagaccagtttgatgtaggttcagctgcagcccggaaagaaatc
ataagaaacaaaattcgagcaattggcaagatggcacgggtcttctctgttctcagggag
gagagtgaaagcgtgctgacactcaagggcctgactcccacagggatgttgcctagtgga
gtgttggctggaggacggcagaccctgcaaagtgccacagttgaggctattgaggctgaa
aaagcaatacgaggattctctccaccacatagaatctgcagttttgaagaggcaaagggt
ttggataggatcaatgagagaatgccaccccggaaagatgctgtacagcaagatggtttc
aattctctgaacaccgcacatgccactgagaaccacgggactggcaaccatagtgcccag
tga

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