Ursus americanus (American black bear): 123776264 Help Entry 123776264         CDS       T07931                                  Symbol SPHK2 Name (RefSeq) sphingosine kinase 2 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism uar  Ursus americanus (American black bear) Pathway uar00600   Sphingolipid metabolism uar01100   Metabolic pathways uar04020   Calcium signaling pathway uar04071   Sphingolipid signaling pathway uar04072   Phospholipase D signaling pathway uar04148   Efferocytosis uar04370   VEGF signaling pathway uar04371   Apelin signaling pathway uar04666   Fc gamma R-mediated phagocytosis uar05152   Tuberculosis Module uar_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     123776264 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     123776264 (SPHK2)    04371 Apelin signaling pathway     123776264 (SPHK2)    04020 Calcium signaling pathway     123776264 (SPHK2)    04072 Phospholipase D signaling pathway     123776264 (SPHK2)    04071 Sphingolipid signaling pathway     123776264 (SPHK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     123776264 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     123776264 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     123776264 (SPHK2) Enzymes [BR:uar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      123776264 (SPHK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  123776264 NCBI-ProteinID:  XP_045628097 LinkDB All DBs Position Unknown AA seq 768 aa AA seqDB search MDGAGLPLALHKDGASGAGCGVVTPPLLRVCPHLLWQLISRSAMPRPVLKLALGRPLRQA RELAGPAPRAPSLARLRPAARPLAERMHTLPPPLGLMGAVGADLRGRLEEDSACEEGAGR PDQELTWSWGHRPRSALDRAEAMAPPPPPPLAASTPLLHGEFGSYPARGSRLALTLTPQA LHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTYPQGRRGGRLGGRR RAARTFRADGAATYEENRAEAQRWAIALMCLLRGLPLPGDGEITPELLPRPPRLLLLVNP FGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDGIITVSGDGL LFEVLNGLLDRPDWEEAVKTPVGILPCGSGNALAGAVNQHGGFEPALGVDLLLNCSLLLC RGGSRPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTLGTVLGLANL HTYRGRLSYLPAAVETASPTPAHGLPRAKSELTLAPAPAPAPPVAHSPLHRSVSDLPLPL PLPKPALTSPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLPSPPSSPKALLSPI TEGVPEMPTTSGLPPPTPDAPGAISTRGPPDHLLPALGTPLPPGWVTLEGDFVLMLAISP SHLGADLVAAPHARFDDGLVHLCWVRGGISRAALLRLFLAMERGSHFSLGCPQLGYAAAR AFRLEPLTPRGVLTVDGEQVEYGPLQAQVHPGLGTLLTGPPGRPGREP NT seq 2307 nt NT seq  +upstreamnt  +downstreamnt atggatggggcagggctaccacttgccctccacaaagatggagccagcggcgctggctgt ggggtcgtgacgccgcctctgctgcgcgtgtgccctcacttactatggcagctgatctcg cgaagcgcgatgccccgcccagttctcaagctcgccctgggcaggcccctgcgccaagct cgcgagctggccggccccgccccccgcgcgccctcactggcgcggctcagaccggccgcg cgcccattggctgagcggatgcacaccctccccccacccctgggtctgatgggggcggtt ggtgctgatttgaggggccgcctggaggaggactcggcgtgtgaggagggtgcggggagg ccagaccaggagctgacctggagctggggccacaggcctagaagcgccctggacagggct gaggccatggcccccccaccaccgccgccattggccgccagcaccccgctcctgcatggc gagttcggctcctacccggcccggggctcccgcctcgcgctcactctcacaccacaggcc ctgcacatacagcggctgcgcccgaagcccgaagcccggccccggggcggcctggtcccg ctggccgaggtgtcaggctgctgcaccctgcggagccgcagcccctcggactcggcagcc tacttctgcatctacacctacccgcagggccggcgcgggggtcggctcgggggccggcgc agagccgcccgcacttttcgggccgacggggcagccacctacgaggagaaccgcgctgag gcccagcgctgggccattgccctcatgtgtctgctccgtggactgccactacctggggac ggggaaataacccccgaactgctgccaaggcccccccgattgctcctattggtcaacccc ttcggggggcggggtctggcctggcaatggtgtaagaaccatgtgctgcccatgatctct gaagctgggctgtccttcaacctcatccagacagagcggcagaaccatgcccgggagctg gttcaggggctgagcctgagcgagtgggacggcatcatcacagtctcgggagacgggctg ctgttcgaggtgctgaatggactcctagaccgccctgactgggaagaagctgtgaagaca cccgtgggcatcctcccctgtggctcaggcaatgccctggctggagccgtgaaccaacat ggggggtttgaacctgccctgggtgtcgacctgctgctcaactgctcgctgctcctttgc cggggtggcagccgcccgctggatctgctctctgtgacgctggcctcgggctcccgctgt ttctccttcctgtccgtggcctggggcttcgtgtcagacgtggacatccagagtgagcgc ttcagggccctgggcagcgcccgcttcacactgggcacggtgctgggcctcgccaacctg cacacctaccgcggacgcctctcctacctccctgctgctgtggaaactgcctcccctacc cctgcccatggcctgccccgtgccaagtcagagctgaccctggccccggccccggccccg gccccgcctgtggcacactcacccctgcatcgctcggtgtctgacctgcctctgcccttg cccctgcccaagcctgccctgacctcccctggctcacctgagcccctgcccatcctgtcc ctcaatggtgggggcccagagttggccggagactggggtggggctggggatgccccactg tccccagaccccctgctgccctcaccacctagctcccctaaggctttactgtcacccatc accgagggggtcccagaaatgccaaccacctctgggctcccacctcccacccctgatgcc ccgggagccatctctaccaggggcccacctgaccacctgctccctgctctgggcacccca ctccccccaggctgggtgacgctggagggggactttgtgctcatgttggccatctcaccc agccacctgggggctgacctggtggcagctccccatgcgcgctttgacgacggcctggtg cacctgtgctgggtgcgtgggggcatctcgcgggctgcgctgctgcgcctttttctggcc atggagcgaggtagccacttcagcctgggctgtccgcagctgggctacgccgcggcccgt gccttccgcctggagcctctcacgcctcgcggcgtgctcactgtggacggagagcaggtg gagtatgggccactgcaggcgcaggtgcatccaggcctcggtacactgctcactgggcct ccgggccgccccggtcgggagccttga

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