Ursus americanus (American black bear): 123778287 Help Entry 123778287         CDS       T07931                                  Symbol CAPN1 Name (RefSeq) calpain-1 catalytic subunit   KO K01367   calpain-1 [EC:3.4.22.52] Organism uar  Ursus americanus (American black bear) Pathway uar04141   Protein processing in endoplasmic reticulum uar04210   Apoptosis uar04217   Necroptosis uar04218   Cellular senescence uar04382   Cornified envelope formation uar05010   Alzheimer disease uar05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:uar00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04141 Protein processing in endoplasmic reticulum     123778287 (CAPN1)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     123778287 (CAPN1)    04217 Necroptosis     123778287 (CAPN1)    04218 Cellular senescence     123778287 (CAPN1)  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     123778287 (CAPN1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     123778287 (CAPN1)    05022 Pathways of neurodegeneration - multiple diseases     123778287 (CAPN1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uar01002]     123778287 (CAPN1) Enzymes [BR:uar01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.52  calpain-1      123778287 (CAPN1) Peptidases and inhibitors [BR:uar01002]  Cysteine peptidases   Family C2: calpain family    123778287 (CAPN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C2 Calpain_III EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_7 CAPN13-like_C_EFh Motif Other DBs NCBI-GeneID:  123778287 NCBI-ProteinID:  XP_045631456 LinkDB All DBs Position Unknown AA seq 715 aa AA seqDB search MAEEIITPVYCTGVSAQVQKQRAKELGLGRHENAIKYMGQDYEQLRAHCLQSGALFRDEA FPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAA IASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHS AQGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK ALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYQGQMVSLIRMRNPWGE VEWTGAWSDGSSEWNSVDPYEREQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS RSIRKWNTMLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEETDDADDDYGGRESGCSF VLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANSSRARSEQFIN LREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTQELDDQIQANLPDEQVLS EEEIDENFKALFRQLAGEDMEISVKELQTILNRIISKHKDLRTKGFSLESCRSMVNLMDR DGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFRLNKKLYELI ITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA NT seq 2148 nt NT seq  +upstreamnt  +downstreamnt atggctgaggagatcatcacccccgtgtactgcacgggggtgtccgcacaagtgcagaag cagcgggccaaggagctgggccttggccgccatgaaaatgccatcaagtacatgggccag gactatgagcagctgcgggctcattgcctgcagagtggggccctcttccgtgatgaggct ttccccccggtgccccagagcctaggctacaaggacctgggccccaactcctccaaaacc tatggcatcaagtggaaacgtcccacggagctgctctcaaacccccagttcattgtggat ggagccacccgcacagacatctgccagggagcactgggggattgttggctcctggctgcc attgcctccctcaccctcaatgacacgcttctgcatcgagtggtaccacacggccaaagc ttccagaatggctatgccggcatcttccatttccagctgtggcagtttggggaatgggtg gatgtggtcgtggatgacctgctgcccatcaaggacgggaagctggtgtttgtgcactcc gcccaaggcaacgagttctggagtgccctgctcgagaaggcctatgccaaggtgaatggc agctatgaggccctctctgggggcagtacttcagagggcttcgaggacttcacaggcggg gtcaccgagtggtatgagctacgcaaggcacccagcgacctctaccaaatcatcctcaag gccctggagcgggggtccctcctgggctgctccattgacatctccagcgttctggacatg gaggccatcaccttcaagaagctggtgaagggccacgcctactctgtgacaggggccaag caggtgaactaccagggccagatggtgagcctgatccggatgcggaatccctggggcgag gtggagtggacgggagcctggagtgacggctcctcggagtggaacagtgtggacccttac gagcgggagcagctccgggtcaagatggaggatggagagttctggatgtccttccgagac ttcatgcgtgagttcacccgcctggagatctgcaacctgacgcccgacgcgctcaagagc cggtcgatccgcaaatggaacaccatgctctatgaggggacctggcggcgggggagcacc gcgggcggctgccggaactacccagccaccttctgggtcaatccccagttcaagatccgg ctggaggagaccgatgatgcggacgatgactacgggggtcgcgagtcaggctgcagcttc gttctagccctcatgcagaagcaccgtcgccgggagcgccgctttggccgcgacatggag accattggcttcgccgtctacgaggtccctccggagctggtgggccagccggccgtgcac ctgaagcgggacttcttcctggctaactcgtcgcgggcgcgctcggagcagttcatcaac ctgcgtgaggtcagcacgcgcttccgcttgccgcccggggaatacgtggtggtgccctcc actttcgagcccaacaaggagggggacttcgtgctgcgcttcttctccgagaagagcgcc gggacccaggagctggacgaccagatccaggccaatctccccgatgagcaagtgctctca gaagaggagattgatgagaacttcaaggccctcttcaggcagctggccggggaggacatg gagatcagcgttaaggagctgcagaccatcctgaacaggatcatcagcaaacacaaggat ctgcgtaccaagggcttcagcctggagtcgtgccgcagcatggtgaacctcatggaccgg gacggcaacgggaagctgggcctggtggagttcaacatcctgtggaatcgcatccggaat tacctgtccatcttccggaagttcgacttggacaagtcgggcagcatgagtgcctacgag atgcggatggccatcgagtctgcaggcttcaggctcaacaagaagctctatgagctcatc atcacccgctactcggagccggacctggccgtggacttcgacaacttcgtgtgttgcctg gtgcgcctggagaccatgttccggtttttcaaaactctggacacagatctggatggcgtc gtgacctttgacttgtttaagtggttacagctgaccatgtttgcatga

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