Ursus americanus (American black bear): 123784520 Help Entry 123784520         CDS       T07931                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism uar  Ursus americanus (American black bear) Pathway uar01524   Platinum drug resistance uar04010   MAPK signaling pathway uar04115   p53 signaling pathway uar04148   Efferocytosis uar04210   Apoptosis uar04215   Apoptosis - multiple species uar04623   Cytosolic DNA-sensing pathway uar04650   Natural killer cell mediated cytotoxicity uar04657   IL-17 signaling pathway uar04668   TNF signaling pathway uar04726   Serotonergic synapse uar04932   Non-alcoholic fatty liver disease uar04933   AGE-RAGE signaling pathway in diabetic complications uar04936   Alcoholic liver disease uar05010   Alzheimer disease uar05012   Parkinson disease uar05014   Amyotrophic lateral sclerosis uar05016   Huntington disease uar05020   Prion disease uar05022   Pathways of neurodegeneration - multiple diseases uar05132   Salmonella infection uar05133   Pertussis uar05134   Legionellosis uar05145   Toxoplasmosis uar05146   Amoebiasis uar05152   Tuberculosis uar05160   Hepatitis C uar05161   Hepatitis B uar05162   Measles uar05163   Human cytomegalovirus infection uar05164   Influenza A uar05165   Human papillomavirus infection uar05167   Kaposi sarcoma-associated herpesvirus infection uar05168   Herpes simplex virus 1 infection uar05169   Epstein-Barr virus infection uar05170   Human immunodeficiency virus 1 infection uar05200   Pathways in cancer uar05203   Viral carcinogenesis uar05205   Proteoglycans in cancer uar05206   MicroRNAs in cancer uar05210   Colorectal cancer uar05222   Small cell lung cancer uar05416   Viral myocarditis uar05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:uar00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     123784520 (CASP3)    04668 TNF signaling pathway     123784520 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     123784520 (CASP3)   09143 Cell growth and death    04210 Apoptosis     123784520 (CASP3)    04215 Apoptosis - multiple species     123784520 (CASP3)    04115 p53 signaling pathway     123784520 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     123784520 (CASP3)    04650 Natural killer cell mediated cytotoxicity     123784520 (CASP3)    04657 IL-17 signaling pathway     123784520 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     123784520 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123784520 (CASP3)    05206 MicroRNAs in cancer     123784520 (CASP3)    05205 Proteoglycans in cancer     123784520 (CASP3)    05203 Viral carcinogenesis     123784520 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     123784520 (CASP3)    05222 Small cell lung cancer     123784520 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     123784520 (CASP3)    05161 Hepatitis B     123784520 (CASP3)    05160 Hepatitis C     123784520 (CASP3)    05164 Influenza A     123784520 (CASP3)    05162 Measles     123784520 (CASP3)    05168 Herpes simplex virus 1 infection     123784520 (CASP3)    05163 Human cytomegalovirus infection     123784520 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     123784520 (CASP3)    05169 Epstein-Barr virus infection     123784520 (CASP3)    05165 Human papillomavirus infection     123784520 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     123784520 (CASP3)    05133 Pertussis     123784520 (CASP3)    05134 Legionellosis     123784520 (CASP3)    05152 Tuberculosis     123784520 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     123784520 (CASP3)    05145 Toxoplasmosis     123784520 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     123784520 (CASP3)    05012 Parkinson disease     123784520 (CASP3)    05014 Amyotrophic lateral sclerosis     123784520 (CASP3)    05016 Huntington disease     123784520 (CASP3)    05020 Prion disease     123784520 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     123784520 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     123784520 (CASP3)    05416 Viral myocarditis     123784520 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     123784520 (CASP3)    04932 Non-alcoholic fatty liver disease     123784520 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     123784520 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     123784520 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:uar01002]     123784520 (CASP3) Enzymes [BR:uar01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      123784520 (CASP3) Peptidases and inhibitors [BR:uar01002]  Cysteine peptidases   Family C14: caspase family    123784520 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  123784520 NCBI-ProteinID:  XP_045641776 LinkDB All DBs Position Unknown AA seq 277 aa AA seqDB search MENTEHTVDAKAIKNSETKILHGSKSVDSGMSLDNSYKMDYPEMGLCIIINNKNFHRSTG MTARSGTDVDAANLRETFTNLKYEVRNKNDLTREEILELMDSVSKEDHSKRSSFVCVLLS HGDEGIIFGTNGPVDLKKLTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGAED DMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCTMLKLYAHKLEFMHILTRVN RKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYLYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacaccgaacacacagtggatgcaaaagccattaaaaattcagaaacaaagatc ttacatgggagcaaatcagtggactctggaatgtccttggacaacagttataaaatggat tatcctgaaatgggtttatgtataataattaataataagaactttcatagaagtactgga atgaccgctcggtctggtacagatgtagatgcagcaaacctccgggaaacattcacgaac ttgaagtatgaagtcaggaataaaaatgatctcacacgcgaagaaattttggaattaatg gacagtgtctctaaagaagatcatagcaaaaggagcagttttgtttgtgtgcttctaagc catggggatgaaggaataatttttggaacaaatggacctgttgacctgaaaaaattaaca ggtttcttcagaggggattactgtcgaagtctgactggaaaacccaaacttttcattatt caggcctgccgaggcacagaactggactgcggtattgagacggacagcggagcagaggac gacatggcctgtcagaaaataccagttgaagcggacttcttgtatgcctattctacagcc cctggttactactcatggcgaaattcgaaggacggatcctggttcatccagtcactttgt acgatgctgaaactgtatgctcacaagcttgagtttatgcacattcttacccgggttaac cggaaggtagccacagaatttgagtccttctctcttgactctgcttttcatggaaagaaa cagattccgtgtattgtgtcgatgctcacaaaagaactgtatctttatcactaa

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