KEGG   Ursus americanus (American black bear): 123793269
Entry
123793269         CDS       T07931                                 
Symbol
MGST2
Name
(RefSeq) microsomal glutathione S-transferase 2
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar00480  Glutathione metabolism
uar00980  Metabolism of xenobiotics by cytochrome P450
uar00982  Drug metabolism - cytochrome P450
uar00983  Drug metabolism - other enzymes
uar01100  Metabolic pathways
uar01524  Platinum drug resistance
uar05200  Pathways in cancer
uar05204  Chemical carcinogenesis - DNA adducts
uar05207  Chemical carcinogenesis - receptor activation
uar05208  Chemical carcinogenesis - reactive oxygen species
uar05225  Hepatocellular carcinoma
uar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    123793269 (MGST2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    123793269 (MGST2)
   00982 Drug metabolism - cytochrome P450
    123793269 (MGST2)
   00983 Drug metabolism - other enzymes
    123793269 (MGST2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123793269 (MGST2)
   05204 Chemical carcinogenesis - DNA adducts
    123793269 (MGST2)
   05207 Chemical carcinogenesis - receptor activation
    123793269 (MGST2)
   05208 Chemical carcinogenesis - reactive oxygen species
    123793269 (MGST2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    123793269 (MGST2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    123793269 (MGST2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    123793269 (MGST2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:uar02000]
    123793269 (MGST2)
Enzymes [BR:uar01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     123793269 (MGST2)
Transporters [BR:uar02000]
 Other transporters
  Pores ion channels [TC:1]
   123793269 (MGST2)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 123793269
NCBI-ProteinID: XP_045654896
UniProt: A0A452SAT6
LinkDB
Position
Unknown
AA seq 146 aa
MAGHSILLAAVSVLSACQQSYFALHVGKARLKYKVTPPAVSGSPEFERIFRAQQNCVEFY
PIFLITLWIAGWYFNQVFATCLGLLYIYARHQYFWGYSEAAKKRITGFRLSLGSLALLTV
LGALGIANSFLDEYLDVNVAKKLRPF
NT seq 441 nt   +upstreamnt  +downstreamnt
atggctgggcattcaatcttgctggctgctgtctccgtcctgtcggcgtgtcagcaaagt
tattttgctttgcacgtaggaaaagcaagattaaaatacaaagttacacccccggcagtc
tctgggtcaccagagtttgaaagaatatttcgtgcacaacaaaactgtgtggagttttac
cccatatttctgattacattgtggatcgctggatggtatttcaatcaagtttttgctacc
tgtctgggtctgctgtacatatatgcccgtcaccagtatttctggggatattcagaagca
gctaaaaaaaggatcaccggtttccggctgagtctggggagtctggccttgctgacagtc
ctaggcgccctgggaattgcaaacagcttcctggacgaatacctggacgtcaatgtcgcc
aagaaactgagacccttctaa

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