KEGG   Ursus americanus (American black bear): 123802589
Entry
123802589         CDS       T07931                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04014  Ras signaling pathway
uar04015  Rap1 signaling pathway
uar04024  cAMP signaling pathway
uar04062  Chemokine signaling pathway
uar04071  Sphingolipid signaling pathway
uar04145  Phagosome
uar04148  Efferocytosis
uar04151  PI3K-Akt signaling pathway
uar04310  Wnt signaling pathway
uar04360  Axon guidance
uar04370  VEGF signaling pathway
uar04380  Osteoclast differentiation
uar04510  Focal adhesion
uar04517  IgSF CAM signaling
uar04520  Adherens junction
uar04530  Tight junction
uar04613  Neutrophil extracellular trap formation
uar04620  Toll-like receptor signaling pathway
uar04650  Natural killer cell mediated cytotoxicity
uar04662  B cell receptor signaling pathway
uar04664  Fc epsilon RI signaling pathway
uar04666  Fc gamma R-mediated phagocytosis
uar04670  Leukocyte transendothelial migration
uar04722  Neurotrophin signaling pathway
uar04810  Regulation of actin cytoskeleton
uar04932  Non-alcoholic fatty liver disease
uar04933  AGE-RAGE signaling pathway in diabetic complications
uar04972  Pancreatic secretion
uar05014  Amyotrophic lateral sclerosis
uar05020  Prion disease
uar05022  Pathways of neurodegeneration - multiple diseases
uar05100  Bacterial invasion of epithelial cells
uar05132  Salmonella infection
uar05135  Yersinia infection
uar05163  Human cytomegalovirus infection
uar05167  Kaposi sarcoma-associated herpesvirus infection
uar05169  Epstein-Barr virus infection
uar05170  Human immunodeficiency virus 1 infection
uar05200  Pathways in cancer
uar05203  Viral carcinogenesis
uar05205  Proteoglycans in cancer
uar05208  Chemical carcinogenesis - reactive oxygen species
uar05210  Colorectal cancer
uar05211  Renal cell carcinoma
uar05212  Pancreatic cancer
uar05231  Choline metabolism in cancer
uar05415  Diabetic cardiomyopathy
uar05416  Viral myocarditis
uar05417  Lipid and atherosclerosis
uar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123802589 (RAC1)
   04014 Ras signaling pathway
    123802589 (RAC1)
   04015 Rap1 signaling pathway
    123802589 (RAC1)
   04310 Wnt signaling pathway
    123802589 (RAC1)
   04370 VEGF signaling pathway
    123802589 (RAC1)
   04071 Sphingolipid signaling pathway
    123802589 (RAC1)
   04024 cAMP signaling pathway
    123802589 (RAC1)
   04151 PI3K-Akt signaling pathway
    123802589 (RAC1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123802589 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    123802589 (RAC1)
   04148 Efferocytosis
    123802589 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123802589 (RAC1)
   04520 Adherens junction
    123802589 (RAC1)
   04530 Tight junction
    123802589 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123802589 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    123802589 (RAC1)
   04620 Toll-like receptor signaling pathway
    123802589 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    123802589 (RAC1)
   04662 B cell receptor signaling pathway
    123802589 (RAC1)
   04664 Fc epsilon RI signaling pathway
    123802589 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    123802589 (RAC1)
   04670 Leukocyte transendothelial migration
    123802589 (RAC1)
   04062 Chemokine signaling pathway
    123802589 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    123802589 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123802589 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    123802589 (RAC1)
   04380 Osteoclast differentiation
    123802589 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123802589 (RAC1)
   05205 Proteoglycans in cancer
    123802589 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    123802589 (RAC1)
   05203 Viral carcinogenesis
    123802589 (RAC1)
   05231 Choline metabolism in cancer
    123802589 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123802589 (RAC1)
   05212 Pancreatic cancer
    123802589 (RAC1)
   05211 Renal cell carcinoma
    123802589 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123802589 (RAC1)
   05163 Human cytomegalovirus infection
    123802589 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123802589 (RAC1)
   05169 Epstein-Barr virus infection
    123802589 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123802589 (RAC1)
   05135 Yersinia infection
    123802589 (RAC1)
   05100 Bacterial invasion of epithelial cells
    123802589 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123802589 (RAC1)
   05020 Prion disease
    123802589 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    123802589 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123802589 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    123802589 (RAC1)
   05415 Diabetic cardiomyopathy
    123802589 (RAC1)
   05416 Viral myocarditis
    123802589 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    123802589 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123802589 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:uar04131]
    123802589 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:uar04147]
    123802589 (RAC1)
   04031 GTP-binding proteins [BR:uar04031]
    123802589 (RAC1)
Membrane trafficking [BR:uar04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    123802589 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    123802589 (RAC1)
  Macropinocytosis
   Ras GTPases
    123802589 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    123802589 (RAC1)
Exosome [BR:uar04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   123802589 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   123802589 (RAC1)
  Exosomal proteins of colorectal cancer cells
   123802589 (RAC1)
  Exosomal proteins of bladder cancer cells
   123802589 (RAC1)
GTP-binding proteins [BR:uar04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    123802589 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 123802589
NCBI-ProteinID: XP_045669381
LinkDB
Position
Unknown
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtcgtgggagacggagctgtaggtaaaacttgcctactg
atcagttatacaaccaatgcatttcctggagaatacatccccactgtctttgacaactac
tccgccaatgttatggtagatggaaaaccggtgaatctgggcttatgggatacagctgga
caagaagattatgaccgattacgtcccttatcctacccgcaaacagatgtattcttaatt
tgcttttctcttgtgagtcctgcatcatttgaaaacgttcgagcaaagtggtaccccgaa
gtgcgacaccactgtcccaacacccccatcatcttggtggggactaaacttgatctcagg
gatgataaagacacgatcgagaagctgaaggaaaagaagctgactcccatcacctacccg
cagggtctggccatggctaaggagatcggtgcggtaaaatacctggagtgctcggcgctc
acgcagcgaggcctcaagacagtgtttgatgaagcgattcgagcggttctctgtcctcct
cccgtcaagaagaggaagagaaaatgcctgctgttgtaa

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