Ursus maritimus (polar bear): 103657769
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Entry
103657769 CDS
T03271
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04020
Calcium signaling pathway
umr04022
cGMP-PKG signaling pathway
umr04024
cAMP signaling pathway
umr04260
Cardiac muscle contraction
umr04261
Adrenergic signaling in cardiomyocytes
umr04270
Vascular smooth muscle contraction
umr04723
Retrograde endocannabinoid signaling
umr04725
Cholinergic synapse
umr04726
Serotonergic synapse
umr04727
GABAergic synapse
umr04911
Insulin secretion
umr04912
GnRH signaling pathway
umr04921
Oxytocin signaling pathway
umr04924
Renin secretion
umr04925
Aldosterone synthesis and secretion
umr04927
Cortisol synthesis and secretion
umr04929
GnRH secretion
umr04934
Cushing syndrome
umr04935
Growth hormone synthesis, secretion and action
umr05010
Alzheimer disease
umr05020
Prion disease
umr05022
Pathways of neurodegeneration - multiple diseases
umr05207
Chemical carcinogenesis - receptor activation
umr05410
Hypertrophic cardiomyopathy
umr05412
Arrhythmogenic right ventricular cardiomyopathy
umr05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103657769 (CACNA1S)
04020 Calcium signaling pathway
103657769 (CACNA1S)
04024 cAMP signaling pathway
103657769 (CACNA1S)
04022 cGMP-PKG signaling pathway
103657769 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
103657769 (CACNA1S)
04929 GnRH secretion
103657769 (CACNA1S)
04912 GnRH signaling pathway
103657769 (CACNA1S)
04921 Oxytocin signaling pathway
103657769 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
103657769 (CACNA1S)
04924 Renin secretion
103657769 (CACNA1S)
04925 Aldosterone synthesis and secretion
103657769 (CACNA1S)
04927 Cortisol synthesis and secretion
103657769 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
103657769 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
103657769 (CACNA1S)
04270 Vascular smooth muscle contraction
103657769 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
103657769 (CACNA1S)
04725 Cholinergic synapse
103657769 (CACNA1S)
04726 Serotonergic synapse
103657769 (CACNA1S)
04723 Retrograde endocannabinoid signaling
103657769 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
103657769 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
103657769 (CACNA1S)
05020 Prion disease
103657769 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
103657769 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
103657769 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
103657769 (CACNA1S)
05414 Dilated cardiomyopathy
103657769 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103657769 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
umr04040
]
103657769 (CACNA1S)
Ion channels [BR:
umr04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
103657769 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
103657769
NCBI-ProteinID:
XP_008683401
UniProt:
A0A384BLE9
LinkDB
All DBs
Position
Unknown
AA seq
1810 aa
AA seq
DB search
MEPSSPHDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPVRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEATMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSKVFYWLVILVVALNTLSIASEHHNQPLWLTHLQDGGQVVRVRRVEKGYW
TSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNFPQ
ALISVFQVLTGEDWNSMMYNGIMAYGGPSYPGVLVCAYFIILFVCGNYILLNVFLAIAVD
NLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSVIAKKLEQKPKGEGIPTTAKLKI
DEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFFIF
SPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFTSV
FTVEIVLKMTTYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSAISVVKILRVLRVL
RPLRAINRAKGLKHVVQCVFVAVRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDLSK
MTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYQ
AIDSYKEDVGPVHNHRVEMAIFFITYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCELN
KNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTVCLGMQHYNQ
SEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSEI
DTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIK
SFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCATG
EAWQEILLACSYGKRCEPGSDYAPGEEYTCGTSFAYYYFISFYMLCAFLIINLFVAVIMD
NFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHR
VACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTS
MKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLRTI
EEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVM
ANQRPLQFAEIEMEELESPVFLEDFPQDPSTNPLARANTNNANANIAYDNSNHSNRQVFS
SVHYEREFPGETETPAARGAFGQLRRVLGPHSKSCVEELKGQLTQREISSSQASPAPCQH
ARAEPPLPEARRSPTPGALPEEASHSSRTKESGSLCQTPATAQLIQEALVRGGLDTLAAD
ANFVMVTGQALADACQMAPEEVEVAATELLKRQESPEGLASALGRWSLRSSLGSLDQHQG
SRETLIPPRP
NT seq
5433 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccacgatgagggcctgaggaagaaacaacccaagaagcccgtt
cctgagattctgccaaggcccccccgggccctgttctgcttgaccctccagaaccccgtg
aggaaggcctgcatcaacatcgtggaatggaaacccttcgagaccatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccggaagacgacaacaac
actctgaaccttggcctggagaaactggagtatttcttcctcattgttttctcgattgaa
gccaccatgaagatcattgcctacggcttcctattccaccaggatgcctatctgcgcagc
ggctggaatgtgctagacttcatcattgtcttcctgggggttttcaccgtgattctggaa
caggttaatgtcatccaaagcaacacagccccgatgagcagcaaaggggctggtctggac
gtcaaggccctgagagccttccgcgtgctcagacccctccggctggtgtcaggggtgccg
agcctgcaggtggtcctcaattccatcttcaaggccatgctgcccctgttccacatcgcc
ctgctcgtcctcttcatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aagatgcataagacctgctacttcattgggacagatatcgtggccaccgtggagaacgag
aagccctcgccctgcgccaggacgggctctgggcgtccatgcaccatcaatggcagcgag
tgtcggggtggctggccggggcccaaccatggcatcacccactttgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggcgaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggag
gaggacctccgaggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctttggatgagggaggctccgacacagaaagcctgtatgaa
atcgagggcctgaacaaaatcatccagttcgtccgccactggaggcagtggaaccgcatc
tttcgctggaagtgccatgatgtgatcaagtccaaagtcttctattggctggtgatcctg
gtcgtggccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctgtggctg
acccacttgcaagatggtggccaggttgtgcgggttcggagagtggaaaaggggtactgg
acgtctctgagcaacctggtggcgtccctgctcaactccatccgctctatcgcctccctg
ctgctgctgctcttcctcttcatcatcatcttcgccctgctgggcatgcagctcttcggg
ggcaggtatgacttcgaggacacggaggtgcgacgcagcaacttcgacaacttcccgcag
gccctcatcagcgtcttccaggtcctgacaggggaagactggaactccatgatgtacaac
gggatcatggcctacggcgggccgtcctaccccggggtgctcgtgtgtgcttatttcatc
atccttttcgtctgtggcaactatatcctgctcaacgtcttcctggccatcgccgtggac
aacctggccgaagcagagagcctgacctctgcccagaaggccaaggcggaagagaagaag
cgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaagtcagttatagcc
aagaagctggaacagaaacccaagggtgagggcatccctaccaccgccaagctgaaaatc
gatgaatttgaatctaatgtcaatgaagtaaaggatccctacccctcggctgacttccca
ggcgatgatgaagaagacgagcctgagatccccgtgagcccccggccacgccccctggcc
gagctgcagctgaaagagaaggcagtacccattccagaagccagctccttcttcatcttc
agccccaccaacaagatccgtgtcctgtgtcatcgcattgtcaacgccacctggttcacc
aacttcatcctgctcttcatcctgctcagcagcgccgcgctggctgccgaggaccccatc
cgggccgagtctgtgaggaatcagatccttgggtattttgacatcgcgttcacctctgtc
ttcaccgtggagatcgtcctcaagatgacgacctacggtgccttcctgcacaagggctcc
ttctgccgcaactacttcaacatcctggacctggtggtggtggccgtgtcccttatctcc
atgggacttgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagggtgctc
cgacccctccgggccatcaacagagccaaagggctgaagcatgtggtgcaatgcgtgttt
gtggctgtccgcacaatcgggaacatcgtcctggtcaccaccctcctgcagttcatgttc
gcctgcatcggcgtccagctcttcaaggggaagttcttcagctgcaatgacttatccaag
atgacagagaaggagtgcaggggctattactatgtgtacaaggatggggaccccacgcag
atggagctgcgtccgcgccagtggatacacagtgatttccactttgacaacgtgctctcg
gccatgatgtcactcttcacggtctccacttttgagggatggcctcagctactctaccag
gccatcgactcgtacaaggaggacgtgggccccgtccacaaccaccgcgtggagatggcc
atcttcttcatcacctacatcatcctcatcgccttcttcatgatgaacatcttcgtgggc
tttgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgagctgaac
aagaaccagcgccagtgcgtgcagtacgccctgaaggcccgcccactgaggtgctatatc
cccaaaaacccgtaccagtaccaggtgtggtatgtggtcacctcgtcctacttcgagtac
ctgatgttcgccctcatcatgctcaacaccgtctgcctgggcatgcagcactacaaccag
tccgaggagatgaaccacatctcagacatcctcaatgtggccttcaccatcatcttcacc
ctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggggacccctgg
aacgtgtttgacttcttgattgtcatcggcagcatcatcgacgtcatcctcagtgaaatc
gacacattcctggcctccagcggaggactgtattgcctgggtggaggctgcgggaacgtt
gaccccgacgagagtgcccgcatctccagcgccttctttcgcctgttccgggtcatgagg
ctgatcaagctgctgagccgggcggagggagtacgcacgctcctgtggaccttcatcaag
tccttccaggccctgccgtatgtggccctgctcatcgtcatgctcttcttcatctacgcc
gtcatcggcatgcagatgttcggtaagatcgccatggtggacgggacccaaataaaccgc
aacaacaacttccagaccttcccacaggcggtgctgctgctcttcaggtgcgcgacaggt
gaggcatggcaggagatcctcctggcctgcagctacggcaagcggtgtgagcccgggtcc
gactacgccccgggggaggagtacacgtgcggcaccagcttcgcctactactacttcatc
agcttctacatgctctgcgccttcctgatcattaacctctttgtagctgtcatcatggac
aactttgactacctcacgcgggactggtccatcctgggccctcatcatctggatgagttc
aaggccatttgggcagagtatgacccggaggctaagggcagaatcaaacacttggatgtg
gtgaccctgctgagacggatccagccccctctgggctttgggaagttctgcccccaccgg
gtggcatgtaagcgcctggtgggcatgaacatgcccttgaacagcgatggcacggtcacc
ttcaacgccactctcttcgccctggtccgtacggcactcaagatcaagacagaaggtaac
tttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagagaaccagc
atgaagctcctggaccaggtcattcctccaattggagatgatgaggtgactgtagggaag
ttctacgccacgtttctcatccaggagcacttccggaagttcatgaagcgtcaggaagag
tattatgggtatcggcccaagaaggacaccatacagatccaggccggattgcggaccatt
gaggaagaggcagccccagagatccgccgcaccatctcaggagacctgacagctgaagag
gagctggagagagccatggtagaggctgcgatggaggaagggatattccggaggactgga
ggcctctttggccaggtggacaacttcctggaaaggaccaactccctgccccctgtcatg
gccaaccagagaccgctccagtttgctgagatagagatggaagagctggaatcacctgtc
ttcttggaggatttccctcaagatccgagcaccaaccctcttgctcgtgccaataccaac
aatgccaacgccaacattgcctatgacaacagcaaccatagcaacaggcaggtgttttcc
agcgtccactatgaaagggagttccctggagagacagagacgcctgctgccagaggagcc
tttggccaactccgaagggtcctgggaccccacagcaaatcctgtgtggaagagctaaaa
ggacagctgacccagagagaaatttccagctcccaggcatctcctgccccctgccagcat
gccagggccgagcctcccctgcctgaggcgaggaggagccctaccccgggcgctctgcct
gaggaagcatcccacagcagtaggaccaaggagagtggttccctgtgccagactccggca
acagcacagctgattcaagaggctctggttcgaggaggcctggacaccttggcggctgac
gctaactttgtcatggtgaccggccaggccctggcagatgcctgccagatggcaccagag
gaagtggaggtggcagccacagagctgctgaaaagacaagagtccccagagggcctggcc
agtgccctgggacgctggagcctcaggtcctcgctgggcagcctggaccagcatcagggc
tccagggagaccctgatcccgcccaggccgtga
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integrated database retrieval system
