Ursus maritimus (polar bear): 103667230
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Entry
103667230 CDS
T03271
Symbol
SLC46A1
Name
(RefSeq) proton-coupled folate transporter
KO
K14613
MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01523
Antifolate resistance
umr04977
Vitamin digestion and absorption
umr04978
Mineral absorption
umr04981
Folate transport and metabolism
umr05215
Prostate cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
103667230 (SLC46A1)
04981 Folate transport and metabolism
103667230 (SLC46A1)
04978 Mineral absorption
103667230 (SLC46A1)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
103667230 (SLC46A1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
103667230 (SLC46A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
umr02000
]
103667230 (SLC46A1)
Transporters [BR:
umr02000
]
Solute carrier family (SLC)
SLC46: Folate transporter
103667230 (SLC46A1)
Major facilitator superfamily (MFS)
Organic acid transporters
Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:
2.A.1.50
]
103667230 (SLC46A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MFS_1
Sugar_tr
Motif
Other DBs
NCBI-GeneID:
103667230
NCBI-ProteinID:
XP_040496981
UniProt:
A0A8M1GMP6
LinkDB
All DBs
Position
Unknown
AA seq
459 aa
AA seq
DB search
MEGRASPPGEARARRGPAVLCRGPVEPLVFLANFSLVLQGPLTTQYLWHRFSADLGYNGT
RDRGSCSNHSADPIMKEVETLTSHWTLYMNLGGFLVGIFSSTLLGAWSDCVGRRPLLVLA
SLGLLLQAVVSIFVVQLQLHVGYFVLGRILCAFLGDFSGLLAASFASVADVSSNRSRTMR
MALLEACIGVAGMLASLLGGHWLRAQGYANPFWLALALLIAMTLYAAFCFGETVKEPTPA
RLFTLRHHRSIVQLYVTPAPEKSRKHLALYSLAVFMVVTVHFGAQDILTLYELSKPLCWD
SKLIGYGSAAQHLPYLTSLLGLRLLQHCLADAWVAEIGLAFNILGMVVFAFATITPLMFT
GYGLLFLSLVTTPIIRAKLSRLVGESEHGALFSAVACTNSLAMLMASGIFNSLYPATLNF
MKGFPFLLGAGLLFIPAILIGVLEKTNPRSEFQQFPQSP
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atggaggggcgcgcgagccccccgggcgaggcccgcgcgcgccgtgggcctgcggtgctg
tgccgcggccccgtggagccgctcgtcttcctcgccaacttctctttggtcctgcagggc
ccgctcaccacgcagtacttgtggcaccgcttcagtgcggacctcggctacaatggcacc
cgcgacaggggcagctgcagcaaccacagcgcggaccccatcatgaaggaagtggagacc
cttacctcccactggaccctctacatgaacctgggcggcttcctggtggggatcttctca
tccaccctgctgggtgcctggagtgactgcgtgggccgccgcccgctgctggtgctggcc
tccctgggcctgttgctgcaggcggtggtgtccatctttgtggtgcagctccagctccac
gtcggctacttcgtgctgggccgcatcctttgcgctttccttggggacttcagtggcctt
ctggccgcaagctttgcttccgtggcagatgtcagctccaaccgcagccgtaccatgcga
atggccttgctggaagcgtgcatcggggtggcagggatgctggcgagcctcctggggggc
cactggctccgggcccagggttatgccaaccccttctggctggccttggccttgttgata
gccatgactctctatgcagccttctgctttggtgagacggtgaaggagccaacgcctgcc
cggctcttcacgctccgtcaccaccgatccatcgtccagctgtacgtgactccagcccca
gagaagtccaggaagcatttggccctgtattcattggccgtcttcatggtagtcactgta
cactttggggcccaggacatcctgaccctctatgagctgagcaaacccctctgctgggac
tccaagctgatcggctacggttctgcggctcagcacctcccctacctcaccagcctgctg
ggcctgcggcttctgcagcactgcctggctgacgcctgggtggccgagattggcctggcc
ttcaacattttggggatggtggtctttgcatttgctactatcacccccctcatgtttaca
gggtatgggctcctgttcctgtcattagtcaccacacccatcatccgggccaaactgtcc
aggctggtgggcgagtcagagcacggtgctctcttttctgctgtggcctgcaccaatagc
ttggccatgctgatggcttctggcattttcaactcgctctacccagccaccctgaacttc
atgaaggggttccccttccttctgggagccggcctcctcttcatcccagccattctgatt
ggggtgctggaaaagactaatcctcgctctgaattccagcagtttcctcagagtccctga
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