Usitatibacter rugosus: DSM104443_00674
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Entry
DSM104443_00674 CDS
T06990
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
uru
Usitatibacter rugosus
Pathway
uru00300
Lysine biosynthesis
uru00550
Peptidoglycan biosynthesis
uru01100
Metabolic pathways
uru01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
uru00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DSM104443_00674 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DSM104443_00674 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DSM104443_00674 (murF)
Enzymes [BR:
uru01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DSM104443_00674 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
POR
Motif
Other DBs
NCBI-ProteinID:
QJR09625
UniProt:
A0A6M4GRD9
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Position
669904..671262
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AA seq
452 aa
AA seq
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MMTLSAAARVLHGRHLGPEAMIAGVTTDSRTIATGDLFVALKGDRFDGHEYVADAIGRGA
AAAMVSREIAADPPLPLVVVDDTRLALGQLASEWRSRFSLPLVALTGSNGKTTVKEMIAA
ILAEHCGAREPVLATAGNYNNDIGMPLTLLRLRDRHRYAVIEMGMNHAGEIDYLTRIAQP
TVALVNNAHRAHVGLLGSVAAIARAKGEIYAGLRPGGVALVNADDPYATAWKALNLDRRT
VTFGLGDTADVRGHVDGTQLQVITPTDAFAVTLQVAGEHNASNAVAAAAAAFALEIPPRA
IQQGLNGFAGVPGRQQRRVSSQGAAVIDDTYNANPDSMKAAARVLALAPGRKVFVMGDMG
ELGDDNAALHAEVGAFAKECGVDRLLALGEASREAVRAFGPGAEHFASLEALMDAARSED
QAGTTILVKGSRFMQMERVAETLAPGGGRHAA
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgatgacgctctccgcagccgcccgcgtcctgcacggacgccacctcggccccgaagcc
atgatcgcgggcgtcacgaccgacagccgcaccatcgccacgggcgacctcttcgtggcg
ttgaagggcgatcggttcgacggccatgaatatgtcgccgacgcgatcggccgcggcgcc
gccgccgcgatggtctcgcgcgagatcgccgccgacccgccgttgccgctcgtcgtcgtg
gacgacacgcgcctcgccctgggacagctcgcgtccgaatggcgctcgcgcttctccctg
ccgctggtggcgctcaccggcagcaacggcaagaccacggtgaaggagatgatcgccgcg
atcctggccgagcactgcggagcgcgcgagcccgtgctcgcgaccgccggcaactacaac
aacgacatcggcatgccgctcacactcctgcggctgcgcgaccgccaccgctacgccgtg
atcgagatgggcatgaaccatgcgggcgagatcgactacctcacgcgcatcgcgcagccc
acggtggcgctcgtgaacaacgcgcaccgcgcgcacgtggggctgctgggcagcgtcgcg
gcgatcgcgcgtgccaagggcgagatctacgcgggcctgcgtcccggcggcgtggcgctc
gtcaacgcggacgatccgtacgccaccgcgtggaaggcactcaacctcgaccggcgcacc
gtgaccttcgggctgggcgacaccgccgacgttcgcggccacgtcgacggcacgcagctg
caggtgatcacgccgacggacgccttcgccgtcacgctgcaggtggcgggcgagcacaac
gccagcaacgccgtcgctgcggcagcggcggccttcgcgctcgagattccgccgcgcgcg
atccagcagggcctgaacggcttcgcgggcgtgccgggccgacaacagcgccgcgtctcc
agccagggcgccgcggtgatcgacgacacgtacaacgccaatcccgattcgatgaaggcc
gcggcccgcgtgctggccctcgcacccggccgcaaggtcttcgtgatgggcgacatgggc
gagctgggcgacgacaacgccgcgctgcacgccgaagtcggggccttcgccaaggagtgc
ggcgtggaccgcttgctggccctcggcgaggcgagccgcgaagcggtgcgcgccttcggc
ccgggcgccgagcacttcgccagcctcgaagcgctgatggacgccgcgagatccgaggac
caggccggcaccacgatcctcgtgaagggctcgcgcttcatgcagatggagcgggtggcc
gaaacgctcgcaccgggaggagggcgccatgctgcttga
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