KEGG   Vulpes vulpes (red fox): 112919676
Entry
112919676         CDS       T05911                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp01522  Endocrine resistance
vvp04010  MAPK signaling pathway
vvp04012  ErbB signaling pathway
vvp04014  Ras signaling pathway
vvp04024  cAMP signaling pathway
vvp04068  FoxO signaling pathway
vvp04071  Sphingolipid signaling pathway
vvp04137  Mitophagy - animal
vvp04140  Autophagy - animal
vvp04141  Protein processing in endoplasmic reticulum
vvp04210  Apoptosis
vvp04215  Apoptosis - multiple species
vvp04217  Necroptosis
vvp04310  Wnt signaling pathway
vvp04380  Osteoclast differentiation
vvp04510  Focal adhesion
vvp04530  Tight junction
vvp04620  Toll-like receptor signaling pathway
vvp04621  NOD-like receptor signaling pathway
vvp04622  RIG-I-like receptor signaling pathway
vvp04625  C-type lectin receptor signaling pathway
vvp04657  IL-17 signaling pathway
vvp04658  Th1 and Th2 cell differentiation
vvp04659  Th17 cell differentiation
vvp04660  T cell receptor signaling pathway
vvp04664  Fc epsilon RI signaling pathway
vvp04668  TNF signaling pathway
vvp04722  Neurotrophin signaling pathway
vvp04723  Retrograde endocannabinoid signaling
vvp04728  Dopaminergic synapse
vvp04750  Inflammatory mediator regulation of TRP channels
vvp04910  Insulin signaling pathway
vvp04912  GnRH signaling pathway
vvp04914  Progesterone-mediated oocyte maturation
vvp04917  Prolactin signaling pathway
vvp04920  Adipocytokine signaling pathway
vvp04926  Relaxin signaling pathway
vvp04930  Type II diabetes mellitus
vvp04931  Insulin resistance
vvp04932  Non-alcoholic fatty liver disease
vvp04933  AGE-RAGE signaling pathway in diabetic complications
vvp04935  Growth hormone synthesis, secretion and action
vvp04936  Alcoholic liver disease
vvp05010  Alzheimer disease
vvp05012  Parkinson disease
vvp05016  Huntington disease
vvp05017  Spinocerebellar ataxia
vvp05020  Prion disease
vvp05022  Pathways of neurodegeneration - multiple diseases
vvp05132  Salmonella infection
vvp05133  Pertussis
vvp05135  Yersinia infection
vvp05142  Chagas disease
vvp05145  Toxoplasmosis
vvp05152  Tuberculosis
vvp05161  Hepatitis B
vvp05162  Measles
vvp05166  Human T-cell leukemia virus 1 infection
vvp05167  Kaposi sarcoma-associated herpesvirus infection
vvp05169  Epstein-Barr virus infection
vvp05170  Human immunodeficiency virus 1 infection
vvp05171  Coronavirus disease - COVID-19
vvp05200  Pathways in cancer
vvp05208  Chemical carcinogenesis - reactive oxygen species
vvp05210  Colorectal cancer
vvp05212  Pancreatic cancer
vvp05231  Choline metabolism in cancer
vvp05415  Diabetic cardiomyopathy
vvp05417  Lipid and atherosclerosis
vvp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    112919676 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112919676 (MAPK10)
   04012 ErbB signaling pathway
    112919676 (MAPK10)
   04014 Ras signaling pathway
    112919676 (MAPK10)
   04310 Wnt signaling pathway
    112919676 (MAPK10)
   04668 TNF signaling pathway
    112919676 (MAPK10)
   04068 FoxO signaling pathway
    112919676 (MAPK10)
   04071 Sphingolipid signaling pathway
    112919676 (MAPK10)
   04024 cAMP signaling pathway
    112919676 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112919676 (MAPK10)
   04137 Mitophagy - animal
    112919676 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    112919676 (MAPK10)
   04215 Apoptosis - multiple species
    112919676 (MAPK10)
   04217 Necroptosis
    112919676 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    112919676 (MAPK10)
   04530 Tight junction
    112919676 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112919676 (MAPK10)
   04621 NOD-like receptor signaling pathway
    112919676 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    112919676 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    112919676 (MAPK10)
   04660 T cell receptor signaling pathway
    112919676 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    112919676 (MAPK10)
   04659 Th17 cell differentiation
    112919676 (MAPK10)
   04657 IL-17 signaling pathway
    112919676 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    112919676 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112919676 (MAPK10)
   04920 Adipocytokine signaling pathway
    112919676 (MAPK10)
   04912 GnRH signaling pathway
    112919676 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    112919676 (MAPK10)
   04917 Prolactin signaling pathway
    112919676 (MAPK10)
   04926 Relaxin signaling pathway
    112919676 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    112919676 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    112919676 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    112919676 (MAPK10)
   04722 Neurotrophin signaling pathway
    112919676 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112919676 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112919676 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112919676 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    112919676 (MAPK10)
   05231 Choline metabolism in cancer
    112919676 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112919676 (MAPK10)
   05212 Pancreatic cancer
    112919676 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112919676 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    112919676 (MAPK10)
   05161 Hepatitis B
    112919676 (MAPK10)
   05171 Coronavirus disease - COVID-19
    112919676 (MAPK10)
   05162 Measles
    112919676 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112919676 (MAPK10)
   05169 Epstein-Barr virus infection
    112919676 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112919676 (MAPK10)
   05135 Yersinia infection
    112919676 (MAPK10)
   05133 Pertussis
    112919676 (MAPK10)
   05152 Tuberculosis
    112919676 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112919676 (MAPK10)
   05142 Chagas disease
    112919676 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112919676 (MAPK10)
   05012 Parkinson disease
    112919676 (MAPK10)
   05016 Huntington disease
    112919676 (MAPK10)
   05017 Spinocerebellar ataxia
    112919676 (MAPK10)
   05020 Prion disease
    112919676 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    112919676 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112919676 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    112919676 (MAPK10)
   05415 Diabetic cardiomyopathy
    112919676 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    112919676 (MAPK10)
   04936 Alcoholic liver disease
    112919676 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    112919676 (MAPK10)
   04931 Insulin resistance
    112919676 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    112919676 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    112919676 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vvp01001]
    112919676 (MAPK10)
Enzymes [BR:vvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     112919676 (MAPK10)
Protein kinases [BR:vvp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   112919676 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 112919676
NCBI-ProteinID: XP_025853927
UniProt: A0A3Q7T1X8
LinkDB
Position
Unknown
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccagttttacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttaaagcctattggctctggggctcagggaatagtttgcgct
gcgtatgatgctgttcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacactggaggagtttcaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgctgtgtggcatcaagcacctt
cactctgctggaattattcacagggatttaaagccaagtaatattgtagtcaagtctgat
tgtacattgaaaattcttgactttggactggccaggacggcaggcacaagcttcatgatg
actccttatgtggttacacgttattatagagcccctgaggttattctgggcatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtaattgaacaactagga
acaccatgtccagaatttatgaagaaattgcaacctacggtaagaaattatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctcttcccagattccctcttcccagcg
gactctgagcacaataaactcaaagccagccaagccagggacttattgtcaaagatgcta
gtgattgaccctgcaaaaaggatatcagtggatgacgccttacagcatccttacatcaat
gtctggtacgaccctgccgaagtggaggcgcctccacctcagatttatgacaaacagttg
gatgaaagagagcacaccattgaagaatggaaagaacttatctacaaggaagtaatgaat
tcggaagaaaagactaaaaacggtgttgtaaaaggacagccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtctgtcaacgacatctcctccatgtcc
accgaccagaccctggcctctgacactgacagcagcctggaagcctcagcaggacccctg
ggttgttgcaggtga

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