Vulpes vulpes (red fox): 112919843 Help Entry 112919843         CDS       T05911                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism vvp  Vulpes vulpes (red fox) Pathway vvp04020   Calcium signaling pathway vvp04371   Apelin signaling pathway vvp04713   Circadian entrainment vvp04921   Oxytocin signaling pathway vvp04970   Salivary secretion vvp05010   Alzheimer disease vvp05012   Parkinson disease vvp05020   Prion disease vvp05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:vvp00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     112919843 (RYR3)    04020 Calcium signaling pathway     112919843 (RYR3)  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     112919843 (RYR3)   09154 Digestive system    04970 Salivary secretion     112919843 (RYR3)   09159 Environmental adaptation    04713 Circadian entrainment     112919843 (RYR3)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     112919843 (RYR3)    05012 Parkinson disease     112919843 (RYR3)    05020 Prion disease     112919843 (RYR3)    05022 Pathways of neurodegeneration - multiple diseases     112919843 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:vvp04040]     112919843 (RYR3) Ion channels [BR:vvp04040]  Voltage-gated cation channels   Ryanodine receptor    112919843 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 EF-hand_8 Motif Other DBs NCBI-GeneID:  112919843 NCBI-ProteinID:  XP_025854130 LinkDB All DBs Position Unknown AA seq 4857 aa AA seqDB search MCVLPQEDEVVLQCIANVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCVCNFVLE QSLSVRALQEMLANTGENGGEGAAQGGGHRTLLYGHAVLLRHSFSGMYLTCLTTSRSQTD KLAFDVGLREHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSVSNGNI QVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTDQNDSQHRRIFY EAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTEDQGLILQDRAKS DTKSTAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSICFVQHMASGLWVTYKAQDA KNPRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQFVSGNNRTAAP IALPIEEVLQTLQDLIAYFQPPEEEMQHEDKQNKLRSLKNRQNLFKEEGMLALVLNCIDR LNIYNSVAHFAGIAREESGTAWKEILNLLYKLLAALIRGNRNNCAQFSNNLDWLISKLDR LESSSGILEVLHCILIESPEALNLIAEGHIKSIISLLDKHGRNHKVLDVLCSLCLCNGVA VRANQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDP FLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRIPRAVASI NQHLLRSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGLFFPVVSFSAGVKVRFLM GGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDAEGVRDLLGTTQSLSQASFIP CPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKRQHPCLVEFSKL PETEKNYNLQMSTETLKTLLALGCHIAHVNPAAEEDLKKVKLPKNYMMSNGYKPAPLDLS DVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKK SNRDSLREAVRTFIGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSYAVRSGKWYFEF EVVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSRGQRWHQGSGYFGRTWQPGDVVGCM INLDDASMIFTLNGELLITNKGSELAFADYEIENGFVPICSLGLSQIGRMNLGMDASTFK FYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPHIEVVRVDGTVDSPPCLKV THRTFGAQSGGARMVYCRLSMPVECRPSPGHGPCLDSDALRRKQMQEILSPTTTQCYYAI RIFAGQDPSCVWVGWVTPDYHLHSEKFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWG GDIVATSQRSSRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQVEPNTKVFPAVFLQPT STSLFQFELGKLKNAMPLSAAIFKSEEKNPVPQCPPRLDVQTIQPVLWSRMPSSFLKVET ERVSERHGWVVQCLEPLQMMALHIPEENRCVDVLELCEQEDLMHFHYHTLRLYSAVCALG NSRVAYALCGHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLAHAKERKLMMKNEYIIP ITSTTRKIRLYPDESKRHGLPGVGLRTCLKPGFRFSTPCFVVTGEEHQKQSPEIPLEILK TKALSMLTEAVQHSGAHIRDPVGGSVEFQFVPVLKLVGTLLVMGVFDDDDVRQILLLIDS SVFGEHGGETEDGTEKEEVTQVEEKAVEAGEKASKEAPVKGLLQTRLPESVKLQMCELLS YLCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTARKTREFRSPPQE QINMLLNFQLGENCPCPEEIREELYDFHEDLLIHCGVPLEEEEEEEEDTSWTGKLRALVY KIKGPPKPEKKQPIEEEERYPTTLKELISQTMIRWAQEDQIQDAELVRMMFTLLQRQYDS IGELLQALRKTYTISQASVSDTINLLAALGQIRCLLSVRMGKEEELLMINGLGDIMNNKV FYQHPNLMRVLGMHETVMEVMVNVLGAEKSQIAFPKMVASCCRFLCYFCRISRQNQKAMF EHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEKVVTYLAGCGLQ SCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPAL RGEGGNGLLAAMQGAIKISENPALDLPSQGYKREVMEDSEDEEIVHMGNAIMSFYSALID LLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPCLNKDGSISEPDMA ANFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALN RYLCSAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRLSKGRSLTKAQRDTIEECLLAIC NHLRPSMLQQLLRRLVFDVPQLNEYCKMPLKLLMNHYEQCWKYYCLPSGWGSYGLAVEEE LHLTEKLFWGIFDSLSHKKYDPDLFRMALPCLSAIAGALPPDYLDTRISAMLEKQISVDA DGNFDPKPINTTNFSLPEKWEYIVTKYAEHSHDKWACDKSQNGWKYGISLDENVKTHPLI RPFKTLTEKEKEIYRWPARESLKTMLAVGWSVERTKEGEALAQQRENEKLRSVSQASQGN SYSPAPLDLSNVVLSRELQGMVEVVAENYHNIWAKKKKLELESKGGGSHPLLVPYDTLTA KEKFRDREKAQDLFKFLQVNGILVSRGMKDMELDASSMEKRFAYKFLKKILKYVDSAQEF IAHLEAIVSSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHRLYFLSSPLKPLSSSGYASH KEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTVMKSGSELVKAGLR AFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHVAQHQFG VDLLLGDVQISCYHILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPTLNRY NPLSVFNTRTPRERSILGMPDTVEEMCPDLPQLEGLMKEISDLAESGARYTEMPHVIEVI LPMLCNYLSYWWERGPEHLPPSTGPWCTKVTSEHLSVILGNILKIINNNLGIDEASWMKR IAVYAQPIISKARPDLLKSHFIPTLEKLKKKAVKTVQEEEQLKADTKGDTQEAELLILDE FAVLCRDLYAFYPMLIRYVDNNRSNWLKSPNADSDQLFRMVAEVFILWCKSHNFKREEQN FVIQNEINNLAFLTGDSKSKMSKAMQVKSGGQDQERRKTKRRGDLYSIQTSLIVAALKKM LPIGLNMCTPGDQELISLAKARYGARDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKD VLKSEEPINPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMA PLYNLPRHRSINLFLHGYQRFWIETEEYSFEEKLVQDLAKSPKEEEEEEEETEKQPDPLH QIILHFSRNALTERSKLEDDPLYTSYSSMMAKSCQSGEDEEEEEDKEKTFEEKEMEKQKT LYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQKMLDYLKEK KDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQNDEFTRD LFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNVIISTVDYLLRLQESISDFYWYYSGKDVI DESGQHNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKL SQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNVEMILKFFD MFLKLKDLTSSDTFKEYDPDGKGIISKKEFQKAMEGQKQYTQSEIDFLLSCAEADENDMF NYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFEPYLGRIEI MGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIF EMQLASQISESDSADRPEEEEEEDEDSSYMLEIEGEEEDSKSLESASAFAMACASVKRNV ANFLKKATLKNLRKQYRKVKKMTVKELVKVFFSFFWMLFLELFRLFFAILGGIFQILWNT VFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDAMDSERAEVTEPGITPELIHFVKAEKG DADVMSDLFGFHPKKEGGLKHGPEVGLGDLSEIIGKDEPPTLESTVRKKRKAQAAEMKAA HDAEGKVEPEKMDLEDGEKEDMAKEEEQAEAPWAEVTKKKKPRRGQKVEKPEAFMANFFK GLEVYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEETEDIANLWNSFN DDEEEEAMVFFVLQESTGYMAPTLRALAVIHTIISLVCVVGYYCLKVPLVVFKREKEIAR KLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAE LLGLDKNALDFSPVEESKAEAASLVSWLSSIDMKYHIWKLGVVFTDNSFLYLAWYTTMSV LGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFR KFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITF FFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTV QEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14574 nt NT seq  +upstreamnt  +downstreamnt atgtgtgttctgccgcaggaagatgaggtggttctccagtgcatcgcaaacgtccacaag gagcaacgcaagttctgcctggcagccgaggggcttggcaaccgcctgtgcttcttggaa cccacgtcagaagccaagtatgttcctccagatctctgtgtctgcaattttgtgctggaa cagtccctctctgtgagagccctgcaggagatgcttgccaacacaggtgaaaatggtggc gaaggggcggcccaaggcgggggccaccggacgctgctgtacggccacgcggttctgctg cgacactccttcagtggcatgtatctaacttgtttgaccacatcaagatcccagacagat aaacttgcctttgatgtaggtctacgggaacatgctacaggagaagcctgttggtggacc atacatcccgcttccaaacagagatccgagggagagaaagttcgaattggtgatgacctc atccttgtcagcgtgtcctctgaaagataccttcatctctcagtatcaaatgggaacata caagtggacgcctcttttatgcaaacactctggaatgtacaccctacgtgctcaggaagt agcattgaagaaggatacctacttggtgggcacgtggtacgtctcttccatggtcatgat gagtgtttgacgataccatctacagaccagaatgattcccagcacaggaggatattctat gaagctgggggagctgggacgcgagccagatccctgtggagagtggaaccccttcggata agttggagtggcagtaacatcagatggggccaggctttccgactccggcatctcacaaca ggccactacctggccttgacagaggaccaaggccttatactgcaggaccgggcaaagtcg gacaccaagtccacagccttctctttccgggcttccaaggaaatcaaggagaaattggat tccagtcacaaacgagatatagaaggcatgggtgttccagaaatcaagtatggagattcc atctgctttgtccagcatatggccagtggtctgtgggtgacctacaaagcacaagatgcc aagaacccccgccttggacctctgaagagaaaggtcattctccatcaggaaggccacatg gatgatgggttaacactgcagagatgccaacgtgaggagtcccaggctgctcggatcatc cggaacacgacagccttattcagccagtttgtaagtggaaacaatcgcacagctgccccc atcgctctgcccatagaagaggtcctgcagaccttacaggacttgattgcctactttcag cccccagaggaggagatgcagcatgaagacaagcagaacaagctccgctcactcaagaac agacagaacctttttaaggaagaaggaatgttggcccttgtgttaaactgcatcgatcgc ttgaatatctataacagcgtggcacactttgcggggattgcaagggaggagagtggcacg gcttggaaagagatcctgaaccttctgtacaaactgctggctgctctcattcgtggaaac agaaacaactgcgcccagttctctaataaccttgattggctcatcagcaaattggacaga ctagaatcttcctcaggtattttggaagttttgcactgcatcttgattgaaagcccagaa gccttaaatctgatagcagagggccacatcaagtccatcatctccctgttggataagcat gggcggaatcacaaggttctggatgtgctgtgctccctctgtctctgcaatggggtcgca gtcagagccaaccagaatctgatttgtgacaacttgctgccccggagaaacctgctcctg cagacacggctgattaatgatgtgacaagcattcggcccaacatcttcctgggagttgct gagggctctgcgcagtacaagaagtggtacttcgagctaatcatcgaccaggtggaccct ttcctaacagctgagcccacacacctgcgggtgggctgggcctcttcctcaggctatgct ccgtaccctggcggaggagaagggtggggaggcaatggtgttggcgatgacctgtactcc tatggctttgatggacttcacctttggtcaggccgcatacccagagccgtagcgtccatc aaccagcacctcctgagatcagacgacgtggtgagctgttgccttgacctcggagtgccc agcatctctttccgcatcaacgggcaacctgtgcaggggatgtttgagaacttcaacaca gatgggctcttcttccctgtggtgagcttctctgcaggtgtcaaagtgcgtttcctgatg ggtggacgtcatggcgaatttaagttcctgcctccatctggctacgccccttgctatgaa gccttacttccgaaagaaaagatgagactggagcctgtcaaagaatataaacgtgacgct gaaggagttagagatctgctgggtaccacccagtccctctctcaagcctctttcatccca tgtcccatagacaccagtcaggtggttttgccacctcacctagaaaagatccgagacaga ctggctgaaaacatccacgagctttggggaatgaataaaatagagcttggctggactttt ggcaagatacgggatgacaataaaagacaacacccctgtcttgtggagttttcaaagctg cctgaaactgagaagaattataacctacaaatgtcaactgaaaccttaaaaaccctcctg gcccttgggtgccacatcgctcatgttaatccagctgctgaggaggacctcaagaaggtc aaattgcccaaaaactatatgatgtccaacggctataaaccagcccctttggacttgtct gatgtgaagctgttaccgcctcaagaaattttagtagataagcttgcagaaaacgcacat aacgtttgggccaaggacagaataaagcaaggatggacctatggcatccaacaggatttg aagaacaaaagaaatccccggctggtgccatatgcattactggatgagcgtaccaagaag tccaacagggacagccttcgtgaagctgttcgcacgtttattggttatggctataacatt gagccatctgaccaagaactagctgacccagctgtggagaaagtcagcatagacaagatt cgatttttccgggtagagcggtcttatgcagtaagatctggaaagtggtattttgagttt gaggtggtgacaggaggagacatgcgcgtcggctgggccaggccaggctgtcggcctgac attgagctgggggccgatgaccaagcctttgtgtttgaaggcagcaggggccagcgttgg catcaaggcagtgggtattttggacgtacatggcagccaggagatgtggttggatgtatg attaacctggatgatgcttcaatgatcttcacactgaatggggagctgctgatcaccaac aaaggctctgaacttgccttcgctgattatgagattgagaatggctttgtgcccatctgc tccctgggactgtctcagatcggccgcatgaatctcgggatggatgccagcaccttcaag ttttataccatgtgtggccttcaagagggctttgagccttttgctgtcaacatgaaccgc gatgtcgcaatgtggttcagcaagcgcctgccgacgtttgtcaacgtgccaaaggatcat ccacatatagaggtggtgagggtggacggcaccgtggacagccccccgtgcctcaaggtg acccacaggacgtttggcgcgcagagcggcggcgcccgcatggtctactgccgcctgagc atgcccgtcgagtgccgcccgtcccccggccacggcccctgtctggacagcgacgccctc aggaggaaacagatgcaagagatactctctcctacaacaacgcagtgctactatgcaatc cgcatctttgctggacaggacccctcctgcgtctgggtcggttgggtcactccagactat cacttacacagtgagaagtttgacctgaataagaactgtacagtgactgtgactctaggg gatgagcgaggccgagtgcatgaaagtgtaaagcgcagcaactgctacatggtctggggt ggggatattgtggccacttcccaaagatcaagtcggagcaacgtggacctggagatcggc tgccttgtggatctggcgatgggcatgttgtctttctccgccaatgggagagaacttggc acctgctaccaggtggagcccaataccaaagtgtttccagcagtcttcctgcagcccacg agcacctccttgtttcagtttgaacttgggaagctgaagaacgcgatgcccctgtcggcg gccatatttaagagtgaagagaagaacccagttccacagtgtccccctcggctggacgtc caaaccatccagcccgtgctctggagccgcatgcccagcagcttcctgaaggtggagaca gagcgggtgagcgagcgccatggctgggtggtgcagtgcctggagcccctgcagatgatg gcgctccacatcccagaggagaacaggtgtgtggatgtcctagagctctgcgagcaggag gacctgatgcacttccattaccacacgctgcgcctctacagtgccgtgtgcgccctggga aacagccgagtggcctacgccctgtgtggccacgtggacctgtcccagctcttctatgcc atagacaacaagtacctccccggcctcctccgctctggtttctatgacctgctcatcagc atccacctggcccatgctaaggagaggaagctaatgatgaagaatgagtacatcattccc atcaccagcaccaccaggaaaatccgcctgtacccagatgagtccaagaggcacgggcta cccggagtgggcctcagaacatgcctcaagccaggattcaggttctccaccccttgcttt gttgtgactggcgaggagcaccagaagcagagccctgagatccccttggagattctcaag acaaaggcactgagcatgctgacggaggcagtgcagcacagcggggctcatatccgggac cccgtcggcgggtctgtagagttccaatttgtgcctgtgctgaaactcgtcgggaccctg ctggtcatgggggtgtttgatgatgatgacgtccggcagatcctcctcctgattgattcc tctgtgtttggggagcatggtggagagacagaggatggcacagagaaggaagaggtgacc caggtggaggagaaggcagtggaggctggggaaaaggccagcaaggaggctccggtcaag ggcttgttgcagacccgactgccagagtccgtcaagcttcagatgtgcgagctcctcagc tacctctgcgactgtgagctacagcatcgagtggaagccattgtggcgttcggcgacatt tacgtctccaaactccaggcaaatcagaagttccgctacaatgagctcatgcaggccttg aacatgtctgcagccctgactgcccggaagaccagggagttccgctcacccccacaggag cagatcaacatgcttcttaactttcaactgggagagaattgcccctgcccagaggagatc cgggaggagctatatgacttccatgaggaccttctcattcactgtggagttccactggag gaggaggaagaagaggaggaggacacctcctggactgggaaactccgtgccttggtgtat aaaatcaaaggccctcccaagcctgagaagaaacagccgatagaagaggaggagagatac cctacaaccttgaaggagctcatctcacagaccatgatccgctgggcccaagaggaccag atccaggatgcggagttggtccggatgatgttcaccctcctgcagaggcagtacgacagc attggggagctgctgcaagccctgcggaagacctataccatcagtcaggcctccgtgagt gataccatcaatctgctggctgccctgggccagatccgctgcctcctcagtgtcaggatg ggcaaggaagaggagctgctcatgatcaatgggctgggagacattatgaacaataaggtg ttttaccagcaccccaacctcatgagagtccttggcatgcacgagaccgtgatggaggtg atggtgaacgtgttgggtgcagagaagtcccagattgcttttccaaaaatggttgctagc tgctgccgcttcctttgctatttctgccgaatcagccggcaaaatcagaaggccatgttt gagcatctaagttacctgctggagaatagcagtgttggcttagcatccccttcaatgaga ggatctaccccactggatgtggcagcttcctctgtgatggacaacaacgagttagcgctg ggcttggaggaaccagatcttgagaaggtggtaacctacttggcaggctgtggcctgcag agctgtcccatgcttctagccaaaggataccctgatgtcggctggaaccccattgaaggg gaacgttacctgtccttcttgaggtttgccgtctttgtgaacagtgaaagtgtggaagaa aatgctagcgtcgtggtcaagctgctcatcagacgcccagagtgcttcgggccagccctg cgaggtgaaggaggaaacggcctattggcagctatgcagggcgccattaagatctctgag aacccagctctcgacctcccctctcagggatacaagagagaagtcatggaggacagtgag gatgaagagatcgtgcacatgggcaacgcaattatgtccttttattcagctcttatagat ctgctgggtcgttgtgctcctgaaatgcatcttatccagacgggaaagggggaagccatc cggatcaggtcaatcctgcgctccctggtccccaccgaggatctggttgggatcatcagc atccccttaaagctgccctgtctgaacaaagatgggtccatcagcgagccggatatggca gccaacttctgccctgaccacaaggctcccatggtgctgttcttggatcgtgtttatggc attaaggatcagacttttctgctccacttgctagaggttggatttttacccgacttaaga gcttctgcctctctagatacagtttccctaagcaccacggaggctgcgcttgcactcaat aggtatttgtgttctgctgtgctcccgctcctcacaagatgcgccccgctctttgccgga acagaacactacacttctttgatcgattctacactacagacaatatataggctttccaag ggacggtccctcaccaaagctcagagggacaccatagaagaatgtttgcttgctatttgc aatcacttgaggccttccatgttacagcaactcttgcgacgtctggtttttgatgtgccg cagctcaacgaatactgcaaaatgcctcttaagcttctgatgaatcactatgaacagtgc tggaagtactactgcctgccttcaggatgggggagctatggtctagctgtggaagaagaa ctgcacctgaccgagaagctcttctgggggatttttgactctctctcccataagaagtac gacccagaccttttccgaatggcccttccttgtctcagtgctatcgccggggccctgcca ccggattacttagataccagaatctcggccatgttggagaaacagatctcagtggatgca gatggcaactttgaccccaaacccatcaacaccacaaatttctcgttgcctgaaaaatgg gaatacatcgtcaccaagtatgctgagcattcacatgataaatgggcctgtgacaagagt cagaatggatggaagtatggaatttccctggatgaaaacgtgaagacccatccactcata aggccttttaagacattaacagaaaaggagaaggagatttaccgctggcctgccagagag tctctgaaaaccatgctggctgtgggctggtctgtggagaggaccaaagagggagaggcc ctggctcaacagcgggaaaatgagaaacttcggagtgtgtcccaggctagccagggcaac agctacagccctgcccccctggatctctccaacgtggtgctttccagagagctccagggg atggtggaagtcgtggctgaaaactatcacaacatctgggccaagaagaagaagctggaa ctggagagcaaaggtggcggcagtcaccctctgttggtgccatatgacaccttgacagcc aaggagaagttcagggaccgggagaaggcacaggacctgtttaaattcctccaagtgaac ggcatcttggtttctagaggtatgaaggatatggagctggatgcctcctccatggaaaag aggtttgcctataaatttttgaagaagatcctgaaatatgttgattccgcccaagagttt attgcccatttggaagccattgtcagcagtgggaaaactgaaaagtctccccatgaccag gagatcaaattctttgccaaagttctcctcccactcgttgaccagtacttcaccaatcac cgcctctacttcctgtcatcccctctgaagccccttagcagcagcggctatgcctctcat aaggagaaagaaatggtggccagcctcttctgcaaactcgctgctcttgttcgacacagg atctccctctttgggagcgattctacaacaatggtgagctgtcttcacatcttagctcag acacttgacacaaggactgtcatgaagtcaggctcagagctggtgaaggctgggttacga gcattctttgaaaatgctgcagaagacttagagaagacttcagaaaatctgaagctcggg aagtttacccattccagaacacagattaaaggcgtgtctcaaaatattaactataccacg gtggctctgctccccatcctgacatccatcttcgagcatgttgctcagcatcagttcggg gtggatttactcttaggtgatgtgcaaatttcatgctaccacatactgtgcagcctctac tcccttgggactggaaagaatatctatgttgaaaggcaacgtcctgcccttggagaatgt ctggcctccctggcagctgccataccagtagcattcctggaacccacccttaaccgctac aatccactctcagtcttcaacaccagaacccccagggagaggtctattctggggatgccg gacaccgtggaagagatgtgccccgacctccctcagctggaaggcctgatgaaggaaatc agcgacctggccgagtcaggggcccgatacacggagatgccccacgtcatcgaggtgatc ttgcccatgctctgcaactacctgtcctactggtgggagcgggggcctgagcacctacct cccagcacagggccctggtgcaccaaggtcacctctgaacacctcagtgtcatcctggga aacattctaaaaatcatcaacaacaatctgggcatcgatgaggcatcctggatgaagcgc attgcagtgtacgcccagccaatcatcagcaaagcacggccagacctgctgaagagccac ttcatcccaactctggagaagctgaagaaaaaggctgtcaagactgtgcaggaggaggag cagctgaaagccgacaccaaaggagacactcaagaggcggagctcctcatcttggacgag tttgcagtcctctgcagagacctctatgccttctaccccatgctgattcgctacgtggac aacaacagatctaactggctcaaaagtcccaatgctgattctgaccagctcttccgcatg gtagctgaggtcttcatcctgtggtgcaaatctcacaacttcaagagggaagagcaaaat tttgtgattcagaatgaaattaataatttggcatttttaactggagacagcaaaagcaag atgtcaaaagccatgcaagtaaagtctggaggccaggaccaggaacggaggaagaccaag cggaggggagacttgtattccatccagacctctctcatcgtggccgcgctcaagaagatg ctgcccattggtttgaatatgtgcacgccgggcgatcaggagctgatctcccttgccaag gcccgctacggcgctagggacacagatgaagaggtaaaggaacatctgcggaacaacttg cacctgcaggaaaagtctgatgacccagcagtaaagtggcagctgaacctctacaaagat gttttaaagagtgaagaaccgatcaatccagaaaagactgtagaacgtgtacagagaatt tcagcagctgtcttccacctggagcaggtggaacagcctttgagatccaagaaggcggtc tggcacaaactgttgtcaaagcagcggaaacgggcagtggtggcctgtttcaggatggcc cctctctataacctgcccaggcaccgctccattaacctcttcctccatggctatcagaga ttttggatagaaacagaggagtattcctttgaagagaaactagtacaggatttggctaaa tcccccaaggaggaagaggaggaggaggaggagacagaaaagcaaccagacccacttcat cagattattctccattttagccgcaatgctctcacggagaggagcaaattggaagacgac cccttgtacacatcctattccagcatgatggccaagagttgtcagagcggggaggatgaa gaagaggaggaagacaaggagaaaacatttgaagagaaagaaatggaaaagcagaaaact ctctatcaacaagcacggctgcatgagcgtggagctgcagagatggtccttcagatgata agtgccagcaaaggtgagatgagccccatggtggttgagactctgaagctggggatcgcc attctgaatgggggcaacgctggtgtacaacagaaaatgctagattacctaaaggagaaa aaggatgctggattctttcaaagcctgtctggtcttatgcagtcttgcagtgtccttgat ttgaatgcctttgagaggcagaataaagctgaaggcctggggatggttactgaggaagga acactcattgttcgagagcgtggtgaaaaagtactccagaatgatgagtttacacgagac ctctttagattcctgcagttactttgtgaaggacataacagtgactttcagaacttccta cggactcagatgggcaataccaccactgtaaacgtcatcatcagtaccgtggactacctc ctacgtctacaggaatccatcagtgatttctactggtattattcagggaaggacgtcatt gatgaatctggacagcacaatttttccaaagctctggcagtcacgaagcagattttcaat tctcttacagaatacatccagggcccttgcattgggaaccaacaaagcctggctcacagc aggctgtgggacgcggtggtcggcttcctccatgtatttgctaacatgcagatgaaactc tctcaggattccagtcagatcgagctgctgaaggaactcttggatctccttcaggacatg gtggtgatgcttctgtccctcctggaagggaatgtggtaaatggaactattggcaagcag atggttgacacactggtagaatcatctaccaatgtagaaatgatcttgaaattctttgac atgttcttgaaacttaaagacctaaccagctcagacaccttcaaagaatatgacccagat ggtaaagggattatctccaaaaaagagttccagaaggccatggaagggcaaaaacagtac acacagtcagagattgactttctcctttcatgtgcagaagctgatgagaatgatatgttt aattacattgattttgtagaccggttccatgagccggccaaggacatagggtttaatgtg gcagtattactgacgaatctctccgaacatatgccaaatgattctcgcctgaagtgtctg ttggacccagcagaaagtgtactaaattactttgaaccctacctggggcgtattgagatc atgggaggggccaagaagattgagcgcgtttattttgaaatcagtgaatccagtcgaacc caatgggagaagccccaagtgaaggaatctaagcggcagttcatctttgatgtggtcaat gaaggtggagagcaagaaaagatggaactgtttgtgaacttctgtgaggataccattttt gaaatgcagttagcatctcagatctctgaatctgactcagctgacagacccgaagaagag gaggaagaagatgaagattcatcttatatgttagaaatcgagggtgaggaggaggacagc aagtctctcgagtctgcctctgcatttgccatggcctgtgcctcagtgaagagaaatgtt gccaactttctgaagaaggcaaccctgaagaacctccggaagcagtacaggaaggtgaaa aagatgactgtgaaggagctggtgaaggtgtttttctctttcttctggatgttgtttctg gagctgttccggttgttcttcgccatattgggaggaatctttcagatcctctggaacaca gtttttggagggggcctagtggaaggggcaaagaacatcagagtgaccaagatcctgggt gacatgcctgacccaacccaatttggtatccatgatgatgccatggattctgagagggca gaggtgaccgagccaggtattacacctgaattgattcacttcgtgaaggctgaaaaggga gacgcagacgtcatgtcagatctctttggattccacccaaagaaagaaggtggcttaaag catgggcccgaagtgggtttgggtgacctctctgagattattggcaaggatgagccacct acactagagagtactgtacggaagaaaagaaaagcacaggcagcagagatgaaagcagca catgatgcagaaggaaaagtggaacccgagaaaatggacctagaagatggggagaaggag gatatggccaaagaggaagaacaggccgaggccccgtgggcagaagtgacaaagaagaag aagccacgtcggggccagaaagtcgagaagcctgaagccttcatggctaatttcttcaaa gggctggaagtctatcagaccaagttactgcattacctcgccaggaatttctacaacctg aggttcctcgctctgtttgtcgccttcgctatcaacttcattctgctcttttacaaggtc actgaagaacctctagaagaagagacagaggacattgcaaatctgtggaattcctttaat gatgatgaagaagaagaagcgatggtgttctttgttctgcaggagagcactgggtatatg gcaccgacgttgcgggccttggccgttatccacaccatcatctctttggtctgtgtggtg ggctattactgcctgaaggtccctctggtggtgttcaaaagggaaaaagaaattgccagg aagctggagttcgatggcctgtacatcactgaacagccatctgaagatgacatcaagggg cagtgggaccgcctggtaatcaacacaccatctttccctaataactactgggacaagttt gtcaagagaaaggtgatcaacaagtatggagatctctacggagcagaacgcattgcggaa ctcctaggtttggacaaaaatgcccttgatttcagcccagtcgaagagagcaaagcagag gcggcctctctggtgtcatggctgagctccattgacatgaagtaccatatctggaaactg ggagttgttttcaccgacaactcgtttctctaccttgcctggtacacaaccatgtcagtc ctgggccactacaacaacttcttttttgctgcgcatctgctggacattgcaatgggcttc aagacgctgaggactattctgtcatctgtaactcacaacggcaaacagctggtcttgacc gtgggtctcctggctgtggtggtctacctctacaccgtggtggccttcaacttctttcgc aagttctacaacaagagtgaagatgacgatgagcccgacatgaagtgtgacgacatgatg acgtgttacctgttccacatgtacgtgggagtgcgcgccgggggcggcatcggagacgaa attgaagaccccgccggagacccctacgagatgtaccgcattgtcttcgacatcacgttc ttcttcttcgtcatcgtcatcctgctggccatcatccaaggtctcatcattgacgccttt ggagagctgagagaccagcaggaacaagtgcgggaggacatggagactaagtgcttcatc tgcgggattggcaacgactactttgacacgactcctcatggcttcgagacacacaccgta caggagcacaacttggccaactatctgttcttcctgatgtatctgattaataaagatgaa acggaacacacggggcaggaatcttatgtctggaagatgtaccaagaaaggtgttgggat ttcttcccagctggtgactgctttcggaaacagtatgaagatcagcttggataa

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