KEGG   PATHWAY: xfn00540Help
Entry
xfn00540                    Pathway                                

Name
Lipopolysaccharide biosynthesis - Xylella fastidiosa M23
Class
Metabolism; Glycan biosynthesis and metabolism
BRITE hierarchy
Pathway map
xfn00540  Lipopolysaccharide biosynthesis
xfn00540

Ortholog table
Module
xfn_M00063  CMP-KDO biosynthesis [PATH:xfn00540]
Other DBs
BSID: 67578
GO: 0009103
Organism
Xylella fastidiosa M23 [GN:xfn]
Gene
XfasM23_0319  acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase [KO:K00677] [EC:2.3.1.129]
XfasM23_1962  UDP-3-0-acyl N-acetylglucosamine deacetylase [KO:K02535] [EC:3.5.1.108]
XfasM23_0321  UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase [KO:K02536] [EC:2.3.1.191]
XfasM23_2070  UDP-2,3-diacylglucosamine hydrolase [KO:K03269] [EC:3.6.1.54]
XfasM23_0318  lipid-A-disaccharide synthase [KO:K00748] [EC:2.4.1.182]
XfasM23_0354  tetraacyldisaccharide 4'-kinase [KO:K00912] [EC:2.7.1.130]
XfasM23_0675  KpsF/GutQ family protein [KO:K06041] [EC:5.3.1.13]
XfasM23_0567  2-dehydro-3-deoxyphosphooctonate aldolase [KO:K01627] [EC:2.5.1.55]
XfasM23_0674  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family [KO:K03270] [EC:3.1.3.45]
XfasM23_1421  3-deoxy-D-manno-octulosonate cytidylyltransferase [KO:K00979] [EC:2.7.7.38]
XfasM23_0071  Three-deoxy-D-manno-octulosonic-acid transferase domain protein [KO:K02527] [EC:2.4.99.15 2.4.99.14 2.4.99.13 2.4.99.12]
XfasM23_0622  lipid A biosynthesis acyltransferase [KO:K02517] [EC:2.3.1.241]
XfasM23_0070  lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase [KO:K02517] [EC:2.3.1.241]
XfasM23_1292  lipopolysaccharide kinase [KO:K11211] [EC:2.7.1.166]
XfasM23_0861  O-antigen polymerase [KO:K02847] [EC:2.4.1.-]
Compound
C00043  UDP-N-acetyl-alpha-D-glucosamine
C00199  D-Ribulose 5-phosphate
C00229  Acyl-carrier protein
C01112  D-Arabinose 5-phosphate
C01187  3-Deoxy-D-manno-octulosonate
C04121  CMP-3-deoxy-D-manno-octulosonate
C04478  3-Deoxy-D-manno-octulosonate 8-phosphate
C04652  UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine
C04738  UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
C04824  Lipid X
C04919  2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
C04932  Lipid A disaccharide
C05223  Dodecanoyl-[acyl-carrier protein]
C05382  Sedoheptulose 7-phosphate
C05761  Tetradecanoyl-[acp]
C06022  UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine
C06024  3-Deoxy-D-manno-octulosonyl-lipid IV(A)
C06025  Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)
C06026  Di[3-deoxy-D-manno-octulosonyl]-lipid A
C06251  Lauroyl-KDO2-lipid IV(A)
C06397  ADP-D-glycero-beta-D-manno-heptose
C06398  ADP-L-glycero-beta-D-manno-heptose
C07836  D-glycero-beta-D-manno-Heptose 7-phosphate
C07838  D-glycero-beta-D-manno-Heptose 1-phosphate
C11472  D-glycero-beta-D-manno-Heptose 1,7-bisphosphate
C19877  4-O-Phospho-alpha-Kdo-(2->6)-lipid IVA
C19878  D-glycero-alpha-D-manno-Heptose 7-phosphate
C19879  D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate
C19880  D-glycero-alpha-D-manno-Heptose 1-phosphate
C19881  GDP-D-glycero-alpha-D-manno-heptose
Reference
PMID:9791168
  Authors
Heinrichs DE, Yethon JA, Whitfield C.
  Title
Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica.
  Journal
Mol Microbiol 30:221-32 (1998)
DOI:10.1046/j.1365-2958.1998.01063.x
Reference
  Authors
Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P.
  Title
Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli.
  Journal
J Bacteriol 184:363-9 (2002)
DOI:10.1128/JB.184.2.363-369.2002
Reference
PMID:9587193
  Authors
Wyckoff TJ, Raetz CR, Jackman JE.
  Title
Antibacterial and anti-inflammatory agents that target endotoxin.
  Journal
Trends Microbiol 6:154-9 (1998)
DOI:10.1016/S0966-842X(98)01230-X
Reference
PMID:9765561
  Authors
Shibayama K, Ohsuka S, Tanaka T, Arakawa Y, Ohta M.
  Title
Conserved structural regions involved in the catalytic mechanism of Escherichia coli K-12 WaaO (RfaI).
  Journal
J Bacteriol 180:5313-8 (1998)
KO pathway
ko00540   
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