KEGG   Xenopus laevis (African clawed frog): 108704008
Entry
108704008         CDS       T01010                                 
Name
(RefSeq) serine/threonine-protein kinase WNK2 isoform X1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
xla  Xenopus laevis (African clawed frog)
Brite
KEGG Orthology (KO) [BR:xla00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:xla01001]
    108704008
   01009 Protein phosphatases and associated proteins [BR:xla01009]
    108704008
Enzymes [BR:xla01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     108704008
Protein kinases [BR:xla01001]
 Serine/threonine kinases: Other
  Wnk family
   108704008
Protein phosphatases and associated proteins [BR:xla01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     108704008
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C Pkinase_fungal
Other DBs
NCBI-GeneID: 108704008
NCBI-ProteinID: XP_041446928
UniProt: A0A8J1N093
LinkDB
Position
4L:153266110..153329068
AA seq 2118 aa
METRAGAASCLGPPSNQPEPPINTEARDKGGATAMLNCNVSAPPAADVCHRVKLRFLRRI
VLDSDQEEPPVLDLSLSGPHNKLIPISRARRAIAKRSQGVSDPGVDNEVSESKGSSSKGG
DAETEPDQPGEPEEKAETPQDVPKCRKEEEEENEEEADIKAVSTSPDGRFLKFDIEIGRG
SFKTVYKGLDTETWVEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESC
LRGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLMFLHTRTPPIIHRDL
KCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGM
CMLEMATSEYPYSECQNAAQIYRKVTSGVKPASFDKVADPEIKEIIGECICKNKEERYGI
KDLLSHAFFAEDTGVRVELAEEDNGRKSSIALRLWVEDAKKLKVKPKDNGAIEFTFDLEK
ETPEDVAQEMVESGFFHENDVKIVGKSIRDRVALIQWRRERICPGHGENEISEQPPVVQP
PLMPLAHSSQIAQYIPSEPEELDTDQHLFHPNLPASITSLASDSTFDSGQGSTVYSDSQS
SQQSVIYSSLPDSLPPAIHRVYSPPILEGQTLLQAQHLGQYQPPTPGIQVATGTLPALGQ
HYQDPNSQYSPVVQANTFPSAQFAQLQSGLSSQPHPVVQQILAPQTMCPVPSSTHPFPQY
QLPPTQLKPLQIPPVPLQHQHPLPSTQLPLYPHISAVTPLPGFETLPANLSDLSALCIAP
MPAPCQYLPPGMVVASIPVTPAIAPPQPVQTINPQLMVPYETNVALNLPVGTVPLLAMAA
TGVQMLPTPQAISQNPQVQPFQAPYPPIIIQSDVPSHTASQQATAPPPQSHHLSIPPPSD
QASAGACNQAVGFPQHPLDVGTAMGFMPVGPSAVMSPPVQFPAEIAPLQPPLEHINPATY
KHTDVAAPLNHQSKSIQTEGHHPETPQPPVYESQTLYQTLRPGEISVEEPHVLENPVSLT
QSSDNYAGSDAASGREMSDGGEGVHGKPTKKHHRRSSRTRSRQEKANKPKLTILNVSNTG
DKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVENGFILQMEKEIFIEQMKDVIDKAE
DMLSEDTEGERSSDQAASPHKVDSHGRETREENAQSQMNTPVYQQNVLHTGKRWFIICPV
AETVGSSLPEMVLTPLNIQKPTDIKDPTVCEDSVFAINADKSDLSVTQNVLCDNASAIPA
SRTQSSSTISSSDLQTQTELSVSALPESLSFLQEEQRHFSPPAVTQPLMDSTAASLIHEA
ARAEVCERMESEQKPSSPSFDPASSTVNPTEPAQAVLSFSNQDRGATHQKQTLDLLLEQN
SLYGSSIGSPVVNSIKPEAPMPSSLASQECQPHPDSDISTPLIPVPAATQSLVMPVGSSS
CQQPSITESDGEGPPRVEFADDTIKCLDEKLRTLLYQEYAPANVPAGTPDNCSGTESGAE
GLYGQPGNGEAVAESRNLSQSISASQEKATELGEIVTETSAYDLPNHKIQASPPNHSQRR
DSGTQKILKETASDSSPNKRETPDKSSKTIGRFSVISTEDDVTMTSPNYMRFSAPPDVYL
DQAPPQPAKPSVPRAHTSSPINSLFCGHVSSDSGDDAPHSKFKDAQPSTPSKGGTNDFMK
KAAAFLHRSGKASTQSPDSPNGQVMKIPSINVTSFHSQSSYMSSDNDSEFEDADMKKELQ
SLREKHMKEITELQVQQKKEIESLYLRLGKPLPPNVGFLHAAPPSGRRRRISKHKLKTGK
LLNPLVQQLKNSTNSPSRISPECNGSPVKDPAKPHADCAAGTSPSHAVQTQQPCSVQVTM
SSDNICCGVIRDGVDVQSSSSQGWTVYHQTSERVTYKSSSKPRTRFLSGPVSLSIWSTLK
RLCLGKDHSSRSSTSSLATAPEASAMPPLNAQPIQPQANNSNNNKKGTFTDDLHKLVDEW
ACKTVGVAQFKPSLNQLKQYQQRQDLELKSVPNDLCDMNRAMPESRKRYSIPMAAPPSVP
LAPLLSSSVPGAVQPGTFVMPFCPYAAPLYGMSWAGAAEHGTAGNQINAQLAPIGNQIFP
VALQHSGLHPAGSNMRIT
NT seq 6357 nt   +upstreamnt  +downstreamnt
atggaaaccagagcaggtgccgcgtcatgtctgggcccccccagtaaccagcctgagccc
cccattaacactgaggccagagataaaggaggggcgactgcaatgctgaactgcaacgtc
tctgctcctccggctgccgacgtctgtcacagagtcaagttgaggttcctcaggaggatt
gtcctggactctgaccaagaggagccccccgtgttggatttatcattatctgggccccac
aacaagctcatccccatctccagggcacggagagccattgccaagaggtctcagggggtc
agcgacccgggagtggacaatgaagtctccgaatcgaaaggttcttcttctaaagggggc
gacgcagaaacagaaccggatcaacccggggaacccgaagagaaagcggaaaccccacaa
gatgtccctaagtgcagaaaagaggaggaagaggagaatgaggaggaggccgatatcaag
gccgtctctacctctcccgatggaaggtttctgaagtttgatattgaaataggaagaggc
tcctttaagacggtctataagggtttggacacggagacgtgggtggaggtggcctggtgt
gagttgcaggaccgtaaattaaccaaattggagcgccagaggtttaaggaggaggcggag
atgctgaaggggttgcagcaccccaatattgtccgcttttatgatttctgggaatcctgt
ctgagggggaagaagtgcatcgtactcgtcacggaactcatgacatcagggacgttaaaa
acatacttgaagagatttaaggtgatgaagccaaaggtcctgcgcagttggtgccggcag
atcctgaaagggttaatgttcctgcacacgcgcacccctcccatcatccaccgggacctc
aaatgtgacaacatcttcatcacgggacccaccggctcggtgaaaatcggagacctcggc
ctggcgaccctgaaacgcgcctctttcgctaaaagcgtaataggcacccccgagttcatg
gcccccgaaatgtacgaggaacattacgacgagtcggtggacgtttacgcttttgggatg
tgcatgctggaaatggcgacttcggaatatccgtactcggaatgccagaacgctgcgcag
atctaccggaaagtgaccagcggggtgaagccggcgagtttcgataaagtggcggatccg
gagatcaaggaaatcatcggcgagtgcatctgtaagaataaagaggagagatacggaatt
aaagacttactaagccacgccttcttcgcggaagacacgggggtgcgggtggagttggcg
gaggaagacaacggtagaaaatcttctattgccctgcggctgtgggtggaagatgcaaag
aagctgaaggtcaaacccaaagataatggcgccattgagttcactttcgacctggagaag
gaaacccccgaggatgttgcacaggagatggtggaatccgggttcttccatgagaacgac
gtgaagatcgtgggcaaatcaataagggacagagttgcgctgatccagtggaggagagag
aggatctgtccagggcacggcgagaacgagatctcggagcagccgccagtagtccagcca
cctctcatgccattggcacactcttcccaaattgcccaatacatcccctctgagccagag
gaactggacactgaccagcacttgtttcaccccaatctgccagccagcatcacatccctt
gcctccgacagcacatttgacagcggccagggctcgactgtatattcggattctcagagc
agtcagcaaagtgtcatctactcctctctgccagactcgctgcctcccgccatccacagg
gtctatagcccccccatcttagagggtcagactttgctgcaggcccagcaccttggccag
taccagccccccacgcctggtattcaagttgctactggcaccctcccggcacttggtcaa
cattaccaagaccccaattcccagtactcgccggtggtacaagcaaatacctttccttct
gcccagtttgctcagttgcagtcggggttatccagccagccgcacccagtcgtacagcaa
atcctggcacctcagaccatgtgccccgtgccgtcgagcacccaccccttcccacagtac
cagctgccacccacccaactgaaacctctccagattcctcctgtgcccctgcagcatcag
cacccacttcccagcacccagcttcctctgtacccccatatttcagcagttactcctctc
ccaggatttgagactctcccggccaatctctctgacttgtctgctctctgtatcgcccca
atgcctgccccctgtcagtacttgcccccaggcatggtggtggcaagtatcccagtgacc
cctgctatagccccacctcagcctgtgcaaaccatcaatccccagttgatggtgccatat
gagaccaacgtagccctgaatctgcccgtgggcaccgttccattactggccatggcagca
actggtgtacaaatgttacccaccccacaggccatttcccagaacccccaagttcagccg
ttccaggcaccctacccacccatcatcattcagagtgatgttccctctcacactgcctcc
caacaagcaacagctccacctcctcaatcccaccatctgagcattcctcctccctccgac
caggcctcggccggggcatgtaaccaggctgttggtttcccccaacatcctctggatgtg
ggaactgccatggggtttatgccagtgggaccttctgcagtgatgtctccaccagtgcag
tttccagctgaaattgcccctctgcagccccctctggaacacatcaaccctgcaacctac
aaacacacagatgtagccgctccactgaatcaccagagcaaatctattcagactgagggt
catcaccccgaaaccccacagccgccagtctatgagagccaaactctctaccaaaccctc
cggcctggggagataagtgtagaggagccgcatgtgctggagaatccagtgagtctgaca
caaagctctgataactatgcaggttcagacgctgcgtctggtagggagatgagtgatggc
ggagaaggtgttcatggaaaaccaaccaaaaagcatcacaggaggtcttcccggactcgc
tcccgccaagagaaggccaataaacccaaattgactattcttaatgtcagtaatacgggt
gacaagatggtggaatgccagctggagacacacaaccataaaatggtaacattcaaattt
gacttggatggcgatgcaccagatgagattgccacatacatggtggagaatggatttatt
ctgcagatggagaaggagatctttattgagcaaatgaaggatgttatagacaaggcagaa
gacatgttgagtgaagatacagagggggagagaagctcggaccaagcggcgagtcctcac
aaagtggattctcatgggagagagacaagggaggaaaatgcccagagtcaaatgaacact
ccggtttatcaacaaaatgttttacatactgggaagagatggtttattatatgtccagtg
gcggaaactgtcggttcctcactgccagaaatggtcctaactcccttaaatatccagaag
ccaacggatattaaagatccgacagtctgtgaggattcagtatttgccataaatgcggat
aagtcggatctttctgtgacgcagaacgtattgtgtgacaacgccagtgccattcctgcc
tcaaggacacaatcttcatctacaatatcctcctcggatcttcaaacccagacagaacta
tcagtttctgcccttcctgagtctctctctttcctccaagaagaacagagacatttcagc
cctcctgcagttacacagcctctaatggactctactgcagcctctcttattcatgaggct
gccagagcggaggtctgtgagaggatggagtccgaacagaaacccagttctccatctttt
gacccagcatctagcaccgtaaatccaaccgaaccggcacaagcagtcctttccttctcc
aaccaagacagaggagccactcatcaaaaacaaactctagatctactcctagagcagaat
tcattgtatggatccagtattggttcccctgttgtaaactccataaaaccagaggccccc
atgcccagttccttggcttctcaggaatgccagccacaccctgattctgatatttctaca
ccactgataccagtgccagctgccactcagtccctggttatgccagttggtagctcatct
tgccaacagcctagtattactgagtcagacggggaaggccccccaagggtagagtttgcg
gatgacactattaaatgcttagatgaaaagcttcgcactctgttgtaccaggaatatgcc
cctgccaatgttcctgccggaacgccagacaactgttctggaacagaaagtggagcagag
ggactttatgggcagccaggcaatggagaggcagttgctgaatccagaaacctctcccag
tccatctctgcatcccaagagaaagcaacggaactcggtgagattgtcactgagacaagt
gcatatgatttgccaaaccacaagattcaggcttcaccaccaaaccattcccagaggagg
gattctggcacccagaagattctgaaagaaactgcttctgattcttctcccaacaagaga
gagactcctgacaagtcctccaaaaccattggcaggttctcagttataagtacagaagat
gacgtcacaatgacctctccaaattacatgagattttcagccccacctgatgtctacctg
gaccaagctccaccacaaccagccaagccctctgtccctagagctcacacctcatccccc
atcaactctctgttctgtggccatgtttctagcgattctggagacgatgcccctcactcc
aaattcaaagatgctcagccatccaccccaagcaaagggggcaccaacgatttcatgaag
aaggctgctgctttcttgcatcgctctggaaaggccagtacccaaagccctgactctcct
aatggccaagtcatgaaaatcccttcaataaacgtgacttctttccattcgcagtcctcc
tacatgagcagtgacaatgactccgagtttgaagatgccgacatgaagaaggaactccag
agcctccgggaaaagcacatgaaagaaataactgaactgcaagtgcagcagaagaaggag
attgagtccttatacctcaggctggggaagcctctgcctcccaatgtggggttcctgcat
gcggcaccccctagcggccgccggaggaggatcagcaaacataagctgaaaactggcaaa
ctgctcaatccgctggtgcagcaattaaagaattcaacaaacagtccaagtcgcatttcc
ccagaatgcaatggctcccctgttaaggatcctgcaaagcctcacgcagactgcgctgca
ggaacctcgccaagccatgccgtacagacgcagcagccttgctctgtccaagtcaccatg
tcgtctgataatatctgttgtggggtcatccgggacggcgtcgatgtgcagagcagttca
agccaaggctggacggtttaccatcaaacgtctgagagagtcacctataaatctagtagc
aaacctcgtacccgattcctcagtggacccgtgtctctgtccatctggtccaccctgaaa
cgcctgtgcctaggcaaagatcacagtagtagatcttcaactagtagccttgcaactgcc
cccgaggcctcagcaatgccaccactcaacgcacaaccaatccaaccgcaggccaacaac
agcaataacaacaagaagggaacgttcacggatgatctccacaagctggtggatgagtgg
gcctgcaaaactgttggtgtggcacaatttaaaccatcattaaaccaactgaagcagtac
cagcagagacaagatctggagctgaagtctgtgcccaacgacctgtgcgacatgaatcgt
gccatgccagaatccagaaagagatacagcattcctatggctgcccctccgtctgtacca
ctggctccactcctgtcctcctctgtccctggagccgtgcagcctggtacctttgtgatg
cccttttgtccatatgcagcaccgttgtatggcatgtcctgggcaggagccgctgagcat
gggactgcaggaaatcagatcaatgcccaattagccccgataggcaaccaaatattccct
gtggcactgcagcactcaggtctgcaccctgctggatccaacatgcggattacgtag

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