Xenopus laevis (African clawed frog): 733357
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Entry
733357 CDS
T01010
Symbol
hsd11b1l.L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
xla
Xenopus laevis (African clawed frog)
Pathway
xla00140
Steroid hormone biosynthesis
xla00980
Metabolism of xenobiotics by cytochrome P450
xla01100
Metabolic pathways
Module
xla_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
xla00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
733357 (hsd11b1l.L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
733357 (hsd11b1l.L)
Enzymes [BR:
xla01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
733357 (hsd11b1l.L)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Epimerase
Polysacc_synt_2
3HCDH_N
Methyltransf_31
Motif
Other DBs
NCBI-GeneID:
733357
NCBI-ProteinID:
XP_018112472
Xenbase:
XB-GENE-5851870
UniProt:
A0A1L8HXM6
A0A974E0X2
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Position
1L:123332803..123351364
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AA seq
293 aa
AA seq
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MGIHVKRWCFLALVASSAYLLRDSFDPATLANARVLVTGASTGIGEEIAYHYARAGAELV
LTARREHALQEVKRRCLELGAKNVSLVVADMASHNAREPVVAEALSALGGLDYLVLNHIG
WTPFKMWDGDVNHTRWLMEVNFLSYIHLATSALPYLAQSKGSIIVLSSLTAKNPIPYTTS
YAASKFALEGFFSSLRHELIMQNNPVSITLCILGLIDTQSAMEKIKDKITLPAYPASDAA
LAVVSAGAGRQREMYYPWYVGPLCFFRDWFPQYRDWIIQSMYHHSSQEEKENP
NT seq
882 nt
NT seq
+upstream
nt +downstream
nt
atgggcattcacgtaaagagatggtgttttcttgcacttgtagcaagttcagcatatctc
ctaagggacagctttgatccagcaactcttgccaatgccagggtcctggtcactggggca
agtacaggcataggggaggagatagcatatcactatgccagggcaggagcagaactggtg
ctgactgcaaggagagagcatgctctgcaagaggtgaaaagaaggtgcctggaacttggg
gctaagaatgtttccctggttgttgcagatatggcctctcataatgcacgggagccagtt
gtagcagaagctctctctgcactgggaggccttgattacttggtattaaaccacattggc
tggacaccattcaagatgtgggatggagatgtgaatcacacccgatggttaatggaggtt
aattttctcagttatattcatttagccacatctgcacttccttacctggcgcaatcaaaa
ggctcaattattgtactttcttcactcacagcaaaaaatcccatcccatataccacatct
tatgcagcttctaagtttgccttggagggttttttcagttctctgagacatgaattgatc
atgcagaacaatcctgtgtccatcaccctctgtattctcggtctcattgacacacagtca
gctatggagaagatcaaggataaaatcaccctgcctgcctatcctgcaagtgatgctgct
cttgctgttgtatcggctggggcaggccgacagcgggagatgtactatccttggtatgtt
ggaccactttgctttttccgagactggttcccacagtacagggactggataatccagagc
atgtaccaccacagctcccaggaggagaaggaaaatccctga
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