Yersinia enterocolitica LC20: LC20_05141
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Entry
LC20_05141 CDS
T03179
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
yel
Yersinia enterocolitica LC20
Pathway
yel00260
Glycine, serine and threonine metabolism
yel00261
Monobactam biosynthesis
yel00270
Cysteine and methionine metabolism
yel00300
Lysine biosynthesis
yel01100
Metabolic pathways
yel01110
Biosynthesis of secondary metabolites
yel01120
Microbial metabolism in diverse environments
yel01230
Biosynthesis of amino acids
Module
yel_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
yel_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
yel_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
yel00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LC20_05141 (metL)
00270 Cysteine and methionine metabolism
LC20_05141 (metL)
00300 Lysine biosynthesis
LC20_05141 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LC20_05141 (metL)
Enzymes [BR:
yel01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LC20_05141 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LC20_05141 (metL)
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Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
AHM76392
UniProt:
A0A7U4GIV8
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All DBs
Position
complement(4551798..4554233)
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AA seq
811 aa
AA seq
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MNATAVAAAVTGRQLHKFGGSSLADVKCYLRVANIMANYSHPGDLMVVSAAGSTTNQLIS
WLKLSQSDRLSAHQVQQNLRRYQHDLISGLLSPEMAEPLISEFIHDLERLAGLLDNKVDD
AIYAEVVGHGEIWSARLMAAVLNKLDMDAAWLDARSFLRAERAAQPQIDEGRSYPLLQQL
MAQHPHQRLVVTGFISRNNTGETVLLGRNGSDYSATQVGALAGVERVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIE
RVLASGSGAKIVTSHDDVCLIELQIASHHDFSLAQKEIDLLLKRAQIKPLATGIHPDRNL
LQLCYTSEVVNSALRVLEDATLPGKLSLREGLALVALVGAGVSKNPLHSHRFYQQLKDQP
VEFIWQAEDGISLVAVLRLGPTEHLIQGLHQSLFRAEKRIGLMLFGKGNIGARWLELFAR
EQKNISARSGFEFVLAGVVDSRRSLLSYDGLDASRTLAFYDDEAQEQDEESLFLWMRAHP
FDDLVVLDVTASESLAEQYLDFASYGFHVISANKLAGASSSNNYRQIRDAFAKTGRHWLY
NATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQFDGTVPFTELVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGADVGSVDQFFENGEALN
QQMIQRLEAANEMGLVLRYVARFDANGKARVGVEAVRADHPLASLLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLSQLL
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgaatgcaacagcggtagcagcggcggtgactggccgtcaactgcataagtttggtggt
agcagcctggcggatgtgaagtgttacctgcgggtggctaatattatggccaactacagt
catcctggcgatcttatggtggtgtctgcggcaggtagcaccacgaaccagctgattagc
tggctgaaactgagtcaaagtgaccgtctttctgctcatcaggtgcagcaaaatttgcgg
cgttaccagcatgacctgattagcggtttattgtcgccagaaatggccgagccgctgatt
agtgagtttatccatgatttggaacgtctggctggcctgttggataacaaagttgatgat
gccatttatgctgaagtggtcggccatggtgagatttggtcggcccgcttgatggctgcg
gtattgaacaaactcgatatggatgctgcctggcttgatgcccgcagcttcctgcgcgcg
gaacgcgcggcacagccacaaatcgacgaaggccgttcttatccgctgttgcagcaattg
atggcgcaacacccgcaccaacggctcgtggtgaccgggtttatctcgcgcaataatacg
ggcgagacggtgctattggggcgtaatggcagtgactactcggccactcaggtcggtgcg
ctagccggtgtcgagcgcgtcaccatctggagtgatgtggctggggtttacagtgctgac
ccgcgtaaagtgaaagacgcctgtttactgccattactgcgcctggatgaagccagtgaa
ttggctcgtttggccgctccagtgctgcacacccgcacactacagccggtttcgggcagt
gatatcgatttgcaactgcgctgtagttatcagccagagcaaggttcgacccgaattgag
cgcgtactggcatctggctccggagccaagattgttaccagccatgatgatgtctgtttg
atcgagttacagattgccagccaccatgatttctcgctagcacagaaagagattgattta
ctgctcaaacgcgcacaaatcaagccgttggcgaccggtattcaccctgaccgcaatcta
ttgcagctttgctatacctcagaagtggttaacagcgcattaagagtgctggaagatgcc
accctgccgggaaaattatcgctgcgggaagggctggcattggttgccttggtgggggcg
ggggtcagcaagaacccattgcatagccaccgtttctatcagcaactgaaagatcaaccg
gttgaatttatttggcaggctgaagacggcatcagtttggttgcggtgctgcgtcttggg
ccgactgaacatttgattcagggcttgcaccagtcattgttccgggcagagaaacgcatt
ggtttgatgctgtttggcaaaggtaatatcggtgcccgctggttggagctatttgctcgt
gagcagaaaaatatctcggcgcgcagtggttttgagttcgtgctggccggtgttgtggat
agccgccgtagcctgctgagttatgacgggctggatgccagccggacgctggcattttat
gatgacgaagcccaagagcaggatgaagaatcgctgttcttgtggatgcgggcgcacccg
tttgatgatttggtggtgttggatgtgaccgcgagtgagtcactggccgagcaatatctg
gatttcgccagctatggtttccatgttatcagtgccaataaattagccggggcatccagc
agcaataactatcgtcaaatccgcgatgcttttgccaaaaccggccgccattggctatat
aacgcgacggttggtgccggtttaccggtaaaccacaccgtgcgcgacctgcgcgatagc
ggcgacagcattctggcgatcagcggtattttctccggcacgctgtcttggctattcctg
caatttgacggcacagtgccctttactgagctggtggatcaagcttggcaacaagggctg
acagaacctgacccgcgggttgatctctccggccaggatgtcatgcgcaagctggtcatt
ttagcgcgtgaagcgggttatgatattgaacccaatcaggtgcgagtggaatcgctggta
cctgctggtgctgatgttggctcagtggaccaattctttgaaaatggcgaagcattgaat
cagcaaatgattcagcgtttagaagcggccaatgaaatgggattggtactacgttatgtt
gcccgctttgatgctaatggtaaggcgcgggtgggtgttgaagcggtgcgagctgaccat
ccattggcctccttgctaccttgcgacaacgtattcgccattgagagccgttggtatcgc
gataacccattggttattcgtggcccaggggcggggcgtgatgtcaccgctggagctatt
cagtccgatttaaaccgcctgtcccaactgctgtaa
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