Zootoca vivipara (common lizard): 118082931 Help Entry 118082931         CDS       T07275                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism zvi  Zootoca vivipara (common lizard) Pathway zvi04020   Calcium signaling pathway zvi04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:zvi00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     118082931 (RYR3)    04020 Calcium signaling pathway     118082931 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:zvi04040]     118082931 (RYR3) Ion channels [BR:zvi04040]  Voltage-gated cation channels   Ryanodine receptor    118082931 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  118082931 NCBI-ProteinID:  XP_034966685 LinkDB All DBs Position LG1:37865587..38141665 Genome browser AA seq 4859 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVANIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNSSEGAAQGGGHRTLLYGHAILLRHSFSGMYL TCLTTSRSQTDKLAFDVGLQENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER YLHLSVAYGNIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVLRLFHGHDECLTIPSAE QNDSPHKRLFFEAGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGQFLALTED LGLVLLDKEKADTKSTSFCFRASKEKLDSAHKRDIDGMGVPEIKYGDSVCFVQHVTSTLW LTYKAQDAKTTRLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTRLFSQFIS GNNRTSTPITLPIEEVLQTLQDLITYFLPPEEELEHEDKQNKLRSLKNRQNLFKEEGMLA LVLNCIDRLNVYYSTAHFTGIGREENGAAWKEILNLLYKLLAALIRGNRNNCAQFSNNLD WLISKLDRVESSSGILEVLHCILIESPEALNLIEEGHIKSIISLLDKHGRNHKVLDVLCS LCLCNGVAVRANQNLICDNLLPRRDLLLQTRLVNDVTSMRPNIFLGIAEGSAQYKKWYFE LIIDQVDPFLTAKPTHLRVGWASALGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGR VPRAVASVNQHLLASEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFFPVVSFSA GVKVRFLIGGRHGEFKFLPPAGYVPCYEALLPKEKMKLEQVKEYKRDLDGVRDLLGTTQF LSQTNFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRQHP CLVEFSKLPETEKNYNIQMSTETLKTLLALGCHVVHINPGAEEDLQKIKLPKNYMMSNGY KPAPLDLSEVKLLPSQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYT LLDERTKKSNRDSLREAVRTFAGYGYNIEPPDQEIADQTVEKVSIDKIRFFRVEQSYAVK TGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGRNWQ PGDVVGCMINLDDKSMIFTLNGELLITNKGSELAFADFEIDNGFVPICSLGLSQIGRMNF GRDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPHIEVTRIDGNI DSPPRLKVTHKTFGTQNSNADMIYCRLSMPIEFHSSFNYSTGLELMDSFQKRKQNQEIPV HATTYYYSVRIFAGQDPSVVWIGWVTPDYHFYSEHFDLNKNCTVTVTLGDERGRVHESVK RSNCYLVWGGETSVNSQRSGRGNVDLEIGCLVELATGMLSFTANGKELGTFYQVEPNTKL FPAAFLQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPIPQCPPRLDVQTITPVVWSRM PNSFLKVEVEKVSDRHGWVVQCLEPLQMMALHIPEESRCIDILELCEQEDLMRFHYHTLK LYSSVCALGNNRVAHILCSHVDVSQLFYTIDNQYLPGLLRSGFYDLLISIHLEYSKEAKL MMNNEFIIPITDETRKIKLFPDESKRHGLPGVGLSTCLKPGFKFSTPCFVLSHEDHQKPS PEIPVEMLKSRAISMLTEAVYCSGTHIRDPVGGKVEFQFVPVLKLIGTLLVMGVFDDHDV KQILLLIDPCVFGETKEEVMEKAEKEDVAQIEEKAIEAGEKAIREPKTPIKGLLQTRLPE SVKLQMCELLNYFCDCELKHRVEAIVSFADTYVSKLQYNQKYRYNELMQALNMSAALTAK KTKEFRSPPQEQINMLLNFQLGEDCPCPEEIQEELYEFHDDLLIHCGIPLEGEEEEEEDL SWTGKLRSLVYKIKGPPKTEKREPTEEEEKYPTTLKELISQTMVRWAQEDQIQDPELVRI MFNLLRRQYDSIGELLQALRKSYTISATSVQDTINLLAALGQIRSLLSVRMGKEEELLMI NGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQIAFPKMVASCCRFLCYFC RISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAAASVMDNNELALALEEPDLEK VVTYLAGCGLQSCPMLLATGYPDIGWNPIEGERYLSFLRFAVFVNGESVEENASVVVKLL IRRPECFGPALRGEGGNGLLAAMQGAIKISENPALDLPSQGYKRELLEEDEEEEEVVHMG NAIMSFYSALIDLLGRCAPELHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPAV NKDGTVTEPDMSASFLPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRACASLDTV SLSTTETALALNRYICTAVFPLLTRCASLFSGTEHYVSLIDSTLHTMYRLSKGRSLTKAQ RDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMSLKLLTNHYEQCWKYYCLPS GWGNYGIAAEEELHLSEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGALPPDYLDTRI TSVLEKQTSVDAEGNFDPKPINTVNFTLPEKLEYIVNKYAEHTHDKWACDKNNSGWKYAS SLDENVKTHPLMRPFRTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEGDPMVQQRESE KLRSISQSSQGNGYNPAPLDLSNVVLSREIQGMVEVVAENYHNIWAKKKKTELESKGGGS HPLLVPYDTLTAKEKSRDREKAQELFKFLLVNGIVISRGLSGMAMDASSMEKRFAYKFLK KILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYFLSSP TKPLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDAATMVSCLHILAQTLDTRTVM KSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPVLT SIFEHVAQHHFGTDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASLAAAI PVAFLEPSLNLYNPLSVFNTKTARERAILGMPESVEEMCPEIPHLDGLMKEINSLAESGA RYTEMPHVIEVILPMLCNYLSYWWERGPENAESSGPCCTMVTSEHLSIILGNILKIINNN LGIDEATWMKRIAVYAQPIISKARPDLLKSHFIPTLEKLKKKAIKIVMEEEQLKADSKTD TQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKKPDADSDELFRMVAEVFILWC KSHNFKREEQNFVIQNEINNLAFLTGDSKSKMSKSGGHDQERKKSKRRGDLYSIQTSLIV AALKKMLPIGLNMCTPGDQELISLAKFRYSCKDTEEEVKEHLRNNLHLQEKSDDPAVKWQ LNLYKDVLKADEPVDPEKIVQRVQRISAAVYHLEQVEQPLRSKKAVWHKLLSKQRKRAVV ACFRMAPLYNLPRHRSINLFLHGYQKFWIETEEYSFEEKLVQDLATPPQKGEEEEEETEK HPDPLHQIILHFSRNALTERSKLEIDPLYTAYSAMMAMSCQSGESDDDEEEKEKTFEEKE MEKQKTLYQQSRLHERGAAEMILQMISASKGEMGHMVVETLKLGIAVLNGGNSVVQQKML DYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQN DEFTKDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYY SGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFA NMQMKLSQDSSQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSNVEM ILKFFDMFLKLKDLTSSEAFKEYDPENKGIISKKEFQKAMEGQKQYTQSEIEFLLSCAET DENDMFNYADFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQTLLDPAECVLNYFEPY LGRIEIMGGAKKIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNF CEDTIFEMQLASQISESDTVDRPEEEEDEPCYVREIGEDEKGEQSLESASAFAMACVAIK KNAATVLKMIRLKNLRKQYRKVRKMTVKELVKVSFSFFWVLFVGFFQMFLTILCSIFQIL WSTVFGGGLIEGAKNIRVTKILGDMPDPTQFGIHDDVLEAEKVEVTEHGITAEIVQFVKN EKGETDILSDIFGIHTKKESGSKHGHAVGLGDIADIIGSDTPPSLESAVRKKKKAQTPEI VKDDESETRTESEKADMEDGEKQDKIKDDMYSEHMEVEEPRKRKRRRGQKIEKPDAVMAN FFKVLEVYQTKMLHFLARNFYNLRFLALFVAFAINFILLFYKVTEEPFEEMEEDSDLWHS LEEEEDEDGVVFYVLQESTGYMAPTLRALAVIHTIISFVCVIGYYCLKVPLVVFKREKDI ARKLEFDGLYITEQPSEDDIKGQWDRLVINTPYFPNNYWDKFVKRKVINKYGDLYGAERI AELLGLDKNALDFSPVEHTELEEASLVLWLSSIDAKYHIWKLGVVFTDNSFLYLAWYTTM SILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNF FRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDI TFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFEMH TLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14580 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgatgaa gtagtgcttcagtgcgttgccaacatccacaaagagcagcgtaagttctgcctggcagct gaggggctcgggaaccgcttgtgctttttggaaccaacttcagaagcaaagtatgtccct cctgacctttgcatctgtaactttgtactggagcagtctttatctgtcagggccctccag gagatgcttgccaatacaggagacaattccagcgaaggggcagctcaaggaggtggtcac agaacactgctatatggccatgctatacttcttcgtcattcatttagtggaatgtatttg acatgtctgactacttcgagatctcagacagataaacttgcatttgatgtggggctacaa gagaatgcagccggtgaggcatgctggtggaccatacatcctgcttctaaacaaaggtct gaaggagaaaaggtacgaattggagacgatcttatcctggttagtgtgtcctccgaaagg tacctgcatctctctgtagcatatggaaacatacaggtggatgcttcctttatgcaaaca ctatggaatgtgcatcccacttgttcaggaagtagcattgaagaaggatacttacttggt gggcatgtattacgtttgtttcacggccacgatgagtgtttaacaattccatctgcagaa cagaatgattcaccacacaagcggttgttttttgaagcagggggagctggtgtccgtgca aggtcactgtggagagttgaaccccttcggataagctggagtggaagtaacatccgctgg ggccagccttttcgccttcgacatattacaacagggcagtttttggccctaactgaagac ctgggtcttgtcttgttagacaaagaaaaagctgacacaaaatcaacttccttttgcttt agagcatcaaaagaaaaactggattctgctcacaaacgtgacatagatggcatgggagtt cctgaaataaagtacggtgattctgtttgttttgtgcaacatgtaaccagcactttgtgg ctcacttacaaagcacaggatgctaaaacaacccgtttaggaccactaaaaagaaaggtt atattacaccaagaaggacacatggatgatggtctcacattacaacggtgtcaacatgaa gaatcccaggctgctcgaatcattcgcaacacaacaagattatttagtcagtttataagt ggaaacaacagaacttcaactcccatcactctgcctattgaagaggtacttcagactctg caagacttgataacatattttctgcctccagaagaagagttagagcatgaagataaacaa aacaagcttcgttcactcaagaacagacagaatctattcaaggaagagggcatgctggca ctggttttgaactgcattgatcgtttaaacgtctactatagcactgctcactttacaggg attggtagagaagaaaatggtgcagcatggaaagaaattctgaaccttctttacaaattg ctagctgctctcattcgtggtaacagaaataattgtgctcagttttcaaataatcttgat tggctaattagtaaattagatagagtagaatcttcctcaggtattttggaggtgttgcac tgcatcctgatagaaagcccagaggctttaaatttgatagaagaaggccatatcaagtct atcatctcgctgctggataagcatgggcgcaaccataaggttctcgatgtgctttgctct ctttgtctttgtaatggagtagcggtgcgagctaatcagaacttaatctgtgacaatctt cttcctcgaagggatctgctcttgcaaacacggcttgtgaatgatgtgacaagtatgagg ccaaacatatttcttggaattgctgaaggctcagcacaatataagaaatggtactttgaa ctaataattgatcaagttgatccatttttgacggcaaaacctacacatctacgggttggc tgggcctcagctttaggctatgctccttatcctggaggtggggaaggatggggaggcaac ggtgttggtgatgacctatactcatatggctttgatggacttcatctatggtctggtcga gtgcccagagcggtggcatctgtcaatcagcatttgttagcatctgaggacgtggtcagc tgctgcttggatttaggggcacccagcatttctttccgcattaatgggcagcctgtgcaa ggaatgtttgagaacttcaacacggatggactttttttccctgtggtgagcttctcagct ggtgtcaaggtacgtttcttaataggtgggcgccatggagagttcaagtttctacctcct gctggctatgtgccttgctatgaagctttgcttccaaaagagaagatgaaactggaacaa gttaaagaatataagagagatttggatggagttagagatttgcttggtaccacacaattt ctttcccaaactaatttcatcccttgtccaattgacaccagccagattgctttgcctttc catcttgagaagatcagagacaagcttgctgaaaatatccatgaactctggggaatgaat aaaatagaacttggctggacttatggcaagatacgagatgataataaaagacaacaccct tgtctggtggaattttcaaaactacctgaaacagagaagaactataacattcaaatgtca acagaaaccctgaaaacgcttttggcccttgggtgtcatgttgttcacattaatccagga gcagaggaagatcttcagaaaatcaaacttcccaaaaattacatgatgtcaaatggctat aagccagcacctctagatctttctgaagtgaaattgctgccttcgcaagaagtgttggtt gacaaacttgcagagaatgcacataacgtctgggcaaaagacagaataaaacaaggttgg acatacggcatccagcaggatctcaaaaacaaacgaaatccccgactggtgccatataca ttattagatgagcgtactaaaaaatcaaacagagatagccttcgtgaagctgtccgcacc tttgctggttatggatataatattgaaccaccagatcaagaaatagctgaccaaacggta gaaaaagtgagcattgacaagatccgtttcttcagagtagagcagtcttacgcagttaag actggaaagtggtattttgaatttgaagctgtaacaggaggagatatgcgtgttgggtgg gcaaggccaggctgtcggcctgacatagaattgggtgctgatgaccaagcatttgtcttt gaaggcagcaagggtcaacgttggcaccaggggagtggcttctttggacgaaattggcaa ccaggagacgtagtgggttgtatgataaatctagatgacaaatcaatgatatttactctg aatggagagttgcttataaccaataaagggtcagaacttgcttttgctgactttgaaata gataatggttttgtccccatatgctcattgggtctgtctcagattggacggatgaacttt gggagagatgccagcacctttaaatattatacaatgtgtggtctgcaggaaggctttgaa ccttttgctgtcaacatgaacagagatgttgctatgtggttcagcaaacgtttaccaaca tttgtcaatgtaccaaaagaccaccctcatattgaggtaacaagaattgatgggaacatt gacagtcctcctcgcttaaaagttacccataagacatttggaacacagaatagtaatgcg gacatgatatattgtcgcttgagcatgccaattgaattccactcctcttttaactacagt actggtttggaactgatggatagtttccaaaaaagaaagcagaaccaggagatacctgtt catgcaacaacgtactactactcagtgcggatctttgcaggccaagacccatctgtagtc tggattggctgggtaacgcctgattaccacttttacagtgaacattttgacctaaataag aactgcacagtaacagttactttgggagatgaaagaggaagagttcatgaaagtgtaaaa cgtagcaattgctacctggtctggggaggagaaacatctgttaattcacaaagatctggt cgtggtaacgttgatttagaaattggatgccttgttgagttggctactggaatgttgtca ttcacagccaatggaaaagaactgggaactttctaccaggttgaaccaaacacaaaatta tttccagcagcttttttacagcctacgagcacaaaccttgtacagtttgaactgggtaaa ttaaagaacactatgcctttatcagcagcaatctttaaaagtgaagagagaaaccctatt ccccagtgccctcctcggctggatgttcaaactatcacacctgttgtgtggagcagaatg ccaaacagtttcctgaaagtagaagttgagaaagtcagtgaccgccatgggtgggtggtc cagtgcctggaacctttgcagatgatggctcttcatattcccgaagaaagcaggtgtatt gatattttagagctatgtgaacaagaggacttgatgaggttccactaccacactttaaaa ctgtatagctctgtttgcgcactgggtaataacagagtagctcatatactttgcagccat gtggatgtttctcagttattttatacaatagataatcaatatttacctggtctcttgcgt tctggattctatgacttacttatcagcattcatttagaatactccaaggaagctaaactc atgatgaacaatgaatttataattccaattacagatgaaaccagaaaaataaaattattt ccagatgaatcgaagagacatggtttgcctggagttgggcttagcacctgcttgaaacca ggcttcaaattctctaccccttgttttgttttgtctcatgaggatcatcaaaaacctagt ccagagataccagttgagatgcttaagtcaagagctataagcatgctaacagaagcggtc tactgcagtggaacacacatacgagaccctgttggggggaaagttgagttccagtttgtt cctgtcctgaaacttataggaacattgcttgtaatgggagtttttgatgatcatgatgtc aaacagattttgctcctcattgatccatgtgtgtttggtgaaaccaaagaagaagtaatg gaaaaagcagagaaagaagatgttgcacaaatagaagaaaaagctatagaggctggagaa aaggcaatcagggagcctaaaactccaataaaaggcttgctgcaaacaagattgcctgaa tctgttaaactccagatgtgtgagctattaaattatttctgcgactgtgaactgaaacac agagtggaagccattgtatcattcgcagatacttacgtctcaaagttgcagtacaatcag aaatatagatataatgaactcatgcaagccttgaatatgtctgctgccttaacagctaag aagacaaaagaatttcgctctcctcctcaagagcagattaatatgttgctaaactttcaa ctgggagaggattgtccttgcccagaggagattcaggaagagttatatgagtttcacgat gatctcctaatccattgtggtattccattagaaggagaagaggaagaagaggaagatctg tcatggactggcaagctacgttcattggtgtataaaataaaaggaccaccaaaaacagaa aagagagaacctacagaggaagaagaaaaatatcccactactctcaaggagttaatatct caaactatggttcgctgggctcaagaagatcagatccaagatccagaattagttcgtatt atgtttaacctccttcgaaggcagtatgacagcattggagagctgcttcaggctctgagg aaatcctacactataagtgctacatctgtgcaagacacaatcaacttattagcagcgctg ggtcaaattcgttcccttctcagcgtcagaatgggaaaagaagaagaattgcttatgatt aatggccttggagatataatgaacaacaaagtattttatcagcatcctaacttaatgaga gtcctgggtatgcatgagacagttatggaagtaatggtaaatgtgcttggaggagacaaa tctcagatcgcttttccaaaaatggtagcaagttgttgtcggttcctgtgctatttttgt cgaatcagtcgccagaaccaaaaagctatgtttgagcatctaagctacttacttgaaaac agcagtgttggacttgcttctccttcaatgaggggttccactccacttgatgtagcagct gcctcagtaatggacaataatgagcttgctctggcgctggaggagccagaccttgagaaa gttgtaacgtacttggcaggctgtggtctccagagctgccccatgcttttagcaacagga tatcctgacattggttggaatccaatagagggtgaacgatatctatcattcttaagattt gctgtttttgtgaatggtgaaagtgtagaggaaaatgccagtgttgttgtcaagcttcta attcggcgtcccgaatgttttgggccagctcttagaggagaaggaggaaatggtttgttg gctgctatgcaaggagcaattaagatatctgagaacccagctcttgatcttccctctcag ggatataagagggaacttcttgaagaagatgaagaagaggaggaggttgtgcatatgggc aatgcaataatgtccttctactcagctctcatagatttgcttgggcgttgtgcaccagaa ttgcatctaatccaaactggaaaaggtgaagctattagaatacgttccatcctgcgttcc ttggtgccaactgaagatttggttgggattataagcatacctctaaaattgccagcagta aataaagatggaactgttacagaaccagacatgtctgcaagtttcttgcctgaccataag gcacccatggtactttttctagatcgtgtctatggtataaaggaccaaagcttccttctc cacctcttggaagttggatttttaccagatttaagagcatgtgcctcattggatacagtt tctttgagtactacagagacagctcttgctctaaacagatatatttgtacagctgtgttt ccattactcacacggtgcgcttccctcttttcggggactgagcattatgtctctctgatt gattctacacttcataccatgtatcgactatccaaaggacgctctcttaccaaagcacag agagacactattgaagaatgtttgcttgctatctgccatcatttacggccttctatgcta cagcagctattacgacggctggtttttgatgtacccttacttaatgaatattgtaaaatg tcacttaagctgctaacaaatcactatgagcaatgttggaaatattattgcttgccttct ggatggggaaattatggaattgcagctgaagaagagttacatttatctgaaaaactcttc tggggaatatttgattccctttctcataagaagtatgatccagagcttttccgaatggcc ttgccttgtttaagtgcaatagctggggctttgccaccagattatttagacacccgaatt acctcagttttagaaaagcagacttcagtggatgctgaagggaactttgaccccaaacct atcaacacagtgaattttacacttcctgaaaagttggagtatattgtcaacaagtatgct gaacatacacatgacaaatgggcctgtgacaagaataatagtgggtggaagtatgcatct tcactcgatgaaaatgtgaagacacatcctttaatgaggccttttagaacactgactgaa aaggaaaaggaaatctatcgatggcctgccagagaatctcttaaaaccatgttagcaatg ggatggagcctagagaggacaaaagaaggagatccaatggtacaacaacgcgaaagtgaa aagctccgtagcatatcacagtccagccaaggaaatggatacaacccagcaccacttgat ctttcaaatgttgtactctccagagaaatccagggaatggttgaagtggtagcagaaaac tatcataacatttgggctaaaaagaagaaaactgaattggaaagtaaaggtggaggtagc catcctttattggtaccgtatgacactttgacagccaaagaaaagtctcgggatagagag aaagcacaagaactgtttaaatttcttctagtgaatggcattgtcatatccagaggctta agtggcatggcgatggatgcttcatccatggaaaagaggtttgcctataaatttctgaag aagattctcaaatacgttgactctgctcaagaattcattgcacatttggaagctattgtc accagtggaaaaacagagaaatccccacatgaccaagaaattaagttctttgccaaagtt ctgcttccactagttgaccagtattttaccaaccattgcctgtatttcctctcctcccca actaagccactcagcagtagtggatatgcttcaaataaagaaaaagaaatggtagcaagc cttttctgcaaacttgctgctcttgttagacataggatttcactttttggtagtgatgct gctacaatggttagctgcctacacatcttagctcagacactagacacaagaaccgtcatg aaatcaggttcagagctggttaaagcaggactgcgtgccttctttgaaaatgcagctgaa gatctggagaagacatcagaaaatcttaaacttggaaaatttacccattcccgtacacaa attaaaggggtctcacagaatatcaactatacaacagtggcattgttgcctgttctaaca tcaatttttgaacatgttgctcagcatcattttggcaccgatttgctattaggtgatgtc caagtatcgtgctacagaattctttgtagcctgtactctcttggaactggaaagaacatt tatgttgaaagacaacgtccggctcttggtgagtgcttagcgtctcttgcagctgcaatt ccagtagcttttctcgaaccttctctcaatctttacaatcccctgtctgtcttcaacaca aaaactgccagagagagagctattttaggcatgcctgaaagcgtagaagaaatgtgtcca gaaatccctcacttggatggcttaatgaaagaaataaacagcttggcagaatctggagcc agatatacagaaatgcctcatgtgattgaggtgatcttgcccatgttatgcaactatcta tcatactggtgggaaagggggcctgaaaatgctgaaagttctggaccctgctgcacaatg gtaacttctgagcatctcagcataatactggggaacattttgaagatcatcaacaataac ctggggatagatgaggcaacttggatgaagcgaatagcagtgtatgctcagccaatcatt agcaaggcgaggccggatctgttgaaaagtcattttatcccaacactggagaaactaaag aagaaagccataaagatagtgatggaggaggaacaactgaaagcagacagtaaaacggat acccaagaagcagaactcctcattctagatgaatttgcagttctttgccgagacctatat gctttttatcctatgttgatccgctatgtggacaacaacagatcaaactggcttaagaaa ccagatgcagattctgatgaacttttccgaatggtagctgaagtcttcattctctggtgt aaatcacataatttcaagcgagaagaacaaaattttgttattcagaatgaaatcaacaat ttggcatttttgacgggagacagcaagagtaagatgtcaaaatctggaggtcatgatcaa gaacgaaagaaatcaaaacgtagaggggatttatattcaatacagacttctctaattgta gctgcacttaaaaaaatgcttcccattggactgaatatgtgtactcctggagatcaagaa ctgatatctcttgctaagttcagatacagctgtaaagacacagaagaagaggtcaaggag cacttacgcaataatttgcatttgcaggagaagtcagatgacccagctgtgaaatggcag ttgaatttgtacaaggatgtcttgaaagctgatgaacctgttgatcctgagaaaatagtg cagcgtgtgcaaaggatctcagcagctgtgtatcatctggaacaggttgagcaaccatta agatcaaagaaagcagtttggcacaaactcttgtcaaaacaacgtaaaagagctgttgtg gcttgtttcaggatggcaccattgtataatctgccaaggcaccgctctattaacctgttc ctccatggttatcagaaattttggatagaaacagaggaatattcctttgaggagaaacta gttcaggatttggctactcccccgcaaaaaggtgaggaggaggaggaagaaactgaaaaa catcctgatcctcttcatcagatcattcttcatttcagccggaatgctctgaccgaacga agcaaattggaaattgaccctttgtacactgcatattcagcaatgatggcaatgagctgt cagagtggagaaagtgatgatgatgaagaagaaaaagagaagacatttgaggaaaaagaa atggaaaagcaaaaaactctttatcagcaatctcgacttcatgaaagaggagcagcagag atgatattacagatgattagtgccagtaaaggtgaaatgggacatatggtagttgaaacc ttgaaacttggtattgctgttctaaatggaggaaactcagttgttcaacagaaaatgttg gactatttgaaggagaaaaaagatgctggattttttcagagtctttctggcttaatgcaa tcttgcagtgttcttgacttgaatgcctttgagagacaaaataaagcagaaggccttgga atggttactgaagaaggaacactcatcgtacgtgagcgtggtgagaaagtactacagaat gatgagtttactaaagatctgtttagatttttacaactgctgtgtgaaggtcataacaat gattttcagaactacctgcgcactcagatgggcaataccaccacagttaatattattatt agcacagttgattatcttttgcgccttcaggaatcaatcagtgacttctactggtactac tctggaaaagatgtcattgatgaatctggacaacgtaatttctctaaagcattggctgtg accaaacagatttttaattcacttactgaatatatccaaggtccttgcattggaaaccag cagagcttggctcacagtagactgtgggatgcagttgttggcttccttcatgtttttgcc aacatgcaaatgaaactttcacaggattcaagtcagatagagttgctgaaggagctacta gatcttctgaaggatatggtggtgatgctgttgtccctacttgaaggtaatgttgtaaat ggcactatcgggaaacagatggtggacactctggttgaatcatctagcaatgtagaaatg atattgaagttctttgacatgttcctcaagttgaaggatctaacaagctcagaagctttc aaagagtatgatcctgaaaataaaggcataatttcaaagaaggaattccagaaagccatg gaaggtcaaaagcagtatacgcaatcggagattgagttcctgctgtcttgtgcggaaacg gatgaaaacgacatgtttaactatgccgattttgttgaaagatttcacgagccagccaaa gatattggatttaatgtggccgtcctcttaacaaacctatcagaacacatgccaaatgat tcgcggcttcaaactctattagatccagcagaatgtgtccttaactattttgaaccttac cttgggcgcattgagataatgggtggtgccaagaagatagagcgggtttattttgagatc agtgaatccagtaggacacagtgggaaaagcctcaagtgaaagaatcaaaaaggcagttt atttttgatgttgtaaatgaaggtggggaacaagagaagatggagctcttcgtgaacttc tgcgaggacacgatttttgaaatgcagttggcatctcagatatctgaatcggatacagtt gacagacctgaggaggaggaagatgagccttgctatgtgagggaaattggagaagatgag aaaggagagcagtcccttgaatcagcttcggcttttgctatggcatgcgttgcaataaag aaaaatgctgccactgttttaaaaatgataagactgaaaaacttaagaaaacagtacaga aaagtgagaaagatgactgtaaaagaattggttaaagtatctttttcctttttctgggtg ctatttgtaggattcttccaaatgtttctcactatactgtgcagtatttttcagattctt tggagtactgtgtttgggggtggcctaattgaaggagccaaaaacattagagttactaaa attttaggagacatgcctgacccaacacagtttggaattcacgacgatgtccttgaagca gaaaaagttgaagttacagaacatggcattacagctgaaattgtgcagtttgtaaaaaat gagaagggagaaacggacatcttgtcagatatttttggcattcatacgaagaaagaaagc ggatcaaagcatggtcatgctgttggcctaggggatatcgctgatatcattggatcagat acccctccttctttggaaagtgcagttcgcaagaagaaaaaagcacagacacctgaaatt gtaaaggatgatgaatcagaaacaagaacagaatccgagaaggctgacatggaggatggc gagaaacaggataaaataaaggatgatatgtattctgaacatatggaagttgaagaacct agaaaacggaaacgaaggcgtgggcaaaaaattgagaaacctgatgcagttatggccaac ttttttaaagtattggaagtttatcagacaaaaatgctgcactttttggcccgaaatttc tacaatttaagatttcttgcactttttgttgcattcgccatcaactttatcctgcttttc tacaaggtgacagaagagccttttgaagaaatggaagaagattcagatctgtggcattct ttagaggaggaagaagatgaagatggagtagtcttctatgttttacaagagagtacaggc tacatggcaccaacacttagggctctagctgttatccatacaatcatctcttttgtatgt gttattggatactattgtttaaaggttcctctggttgtattcaaacgggagaaggacatt gcaaggaagctggaatttgatggtctctatattactgaacaaccctccgaagatgacatt aaaggacagtgggatcgcctggtcataaatacgccatattttcctaataattattgggac aagtttgtaaaacgaaaggtaatcaacaagtatggagatttatatggagcagaacgcatt gcagaactcctgggtctggacaaaaatgctctggacttcagcccagtggaacatactgaa ctagaggaggcatctcttgttttgtggttaagttctattgatgccaaataccatatctgg aagcttggtgtagttttcactgataattccttcttgtacttagcttggtacacaaccatg tcaattcttggtcattacaacaacttcttctttgctgcccacttgctcgatattgctatg ggttttaagactttgcgtaccatcctgtcttctgtaacccacaacggcaaacagcttgtt ttgactgttggactcttggctgtagtggtatacctttacacggttgtggcattcaacttc ttccgcaaattttataacaagagtgaagatgaagatgagccagacatgaagtgtgatgac atgatgacttgttacctcttccacatgtatgtgggtgtaagagcaggtggaggcattgga gatgaaattgaagaccctgcaggagacccttatgagatgtatcgaattgtttttgatatc acgtttttcttctttgtcattgtcatcctactggccatcattcaaggtctgattattgat gcctttggtgaattaagagaccagcaagagcaggtgaaagaagatatggagaccaaatgt tttatttgtggaattggtaatgactattttgacacaaccccccatggatttgaaatgcat actttacaagagcacaacttggccaactacctgttctttctgatgtacctcattaataag gatgaaactgagcacactggacaggagtcttatgtatggaaaatgtaccaagaaagatgc tgggattttttcccagctggagactgcttccgtaaacagtatgaagatcaacttggataa

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