{ "name":"aalb01001", "children":[ { "name":"Serine\/threonine kinases: AGC group", "children":[ { "name":"PKA family", "children":[ { "name":"109416633 cAMP-dependent protein kinase catalytic subunit 1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"109421435 cAMP-dependent protein kinase catalytic subunit beta-like\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"109432573 cAMP-dependent protein kinase catalytic subunit beta-like\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"115261557 cAMP-dependent protein kinase catalytic subunit 1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"109408802 LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit 3-like\tK19584 PRKX; protein kinase X [EC:2.7.11.11]" }, { "name":"109408804 cAMP-dependent protein kinase catalytic subunit PRKX-like\tK19584 PRKX; protein kinase X [EC:2.7.11.11]" } ] }, { "name":"PKG family", "children":[ { "name":"109397574 LOW QUALITY PROTEIN: cGMP-dependent protein kinase 1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]" }, { "name":"109433057 cGMP-dependent protein kinase, isozyme 2 forms cD4\/T1\/T3A\/T3B isoform X1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]" }, { "name":"109621380 LOW QUALITY PROTEIN: cGMP-dependent protein kinase, isozyme 1-like\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]" }, { "name":"109621502 cGMP-dependent protein kinase 1-like\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]" }, { "name":"115268590 LOW QUALITY PROTEIN: cGMP-dependent protein kinase, isozyme 1-like\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]" } ] }, { "name":"PKC family [OT]", "children":[ { "name":"109413923 LOW QUALITY PROTEIN: protein kinase C\tK18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]" }, { "name":"109621323 atypical protein kinase C isoform X1\tK06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]" } ] }, { "name":"PKN family", "children":[ { "name":"109408749 serine\/threonine-protein kinase N isoform X1\tK23691 PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]" }, { "name":"115254603 uncharacterized protein LOC115254603\tK23691 PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]" }, { "name":"115254604 uncharacterized protein LOC115254604\tK23691 PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]" }, { "name":"115254605 uncharacterized protein LOC115254605\tK23691 PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]" } ] }, { "name":"AUR family [OT]", "children":[ { "name":"109405055 LOW QUALITY PROTEIN: aurora kinase C\tK11481 AURKA; aurora kinase A [EC:2.7.11.1]" }, { "name":"109621876 aurora kinase C\tK11481 AURKA; aurora kinase A [EC:2.7.11.1]" }, { "name":"109397302 aurora kinase B-like\tK11479 AURKB; aurora kinase B [EC:2.7.11.1]" }, { "name":"109423204 aurora kinase B\tK11479 AURKB; aurora kinase B [EC:2.7.11.1]" }, { "name":"115267000 aurora kinase B-like\tK11479 AURKB; aurora kinase B [EC:2.7.11.1]" } ] }, { "name":"PDK1 family", "children":[ { "name":"109402475 3-phosphoinositide-dependent protein kinase 1-like\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]" }, { "name":"109416607 3-phosphoinositide-dependent protein kinase 1-like\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]" }, { "name":"109432818 3-phosphoinositide-dependent protein kinase 1-like\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]" }, { "name":"115261561 3-phosphoinositide-dependent protein kinase 1-like\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]" } ] }, { "name":"AKT\/PKB family", "children":[ { "name":"109401058 RAC serine\/threonine-protein kinase\tK04456 AKT; RAC serine\/threonine-protein kinase [EC:2.7.11.1]" } ] }, { "name":"SGK family [OT]" }, { "name":"RSK family [OT]", "children":[ { "name":"109409576 ribosomal protein S6 kinase 2 beta isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"109430456 ribosomal protein S6 kinase 2 beta isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"109420217 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-5-like\tK04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]" }, { "name":"109418942 ribosomal protein S6 kinase beta-2 isoform X1\tK04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]" }, { "name":"109405847 ribosomal protein S6 kinase delta-1\tK20839 RSKL; ribosomal protein S6 kinase-like" } ] }, { "name":"NDR family", "children":[ { "name":"109407933 serine\/threonine-protein kinase tricorner\tK08790 STK38; serine\/threonine kinase 38 [EC:2.7.11.1]" }, { "name":"109413849 serine\/threonine-protein kinase tricorner\tK08790 STK38; serine\/threonine kinase 38 [EC:2.7.11.1]" }, { "name":"115268462 serine\/threonine-protein kinase tricorner-like\tK08790 STK38; serine\/threonine kinase 38 [EC:2.7.11.1]" }, { "name":"109622734 LOW QUALITY PROTEIN: serine\/threonine-protein kinase Warts\tK08791 LATS1_2; serine\/threonine-protein kinase LATS1\/2 [EC:2.7.11.1]" } ] }, { "name":"MAST family [OT]", "children":[ { "name":"109425978 microtubule-associated serine\/threonine-protein kinase 3 isoform X1\tK08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]" }, { "name":"115268068 microtubule-associated serine\/threonine-protein kinase 3-like isoform X1\tK08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]" }, { "name":"109425329 LOW QUALITY PROTEIN: serine\/threonine-protein kinase greatwall\tK16309 MASTL; serine\/threonine-protein kinase greatwall [EC:2.7.11.36]" } ] }, { "name":"YANK family", "children":[ { "name":"109401821 serine\/threonine-protein kinase 32C-like\tK08793 STK32; serine\/threonine kinase 32 [EC:2.7.11.1]" }, { "name":"109410355 serine\/threonine-protein kinase 32B-like\tK08793 STK32; serine\/threonine kinase 32 [EC:2.7.11.1]" } ] }, { "name":"DMPK family [OT]", "children":[ { "name":"109424970 rho-associated protein kinase 1-like isoform X1\tK04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]" }, { "name":"109431113 LOW QUALITY PROTEIN: rho-associated protein kinase 1\tK04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]" }, { "name":"109402277 LOW QUALITY PROTEIN: serine\/threonine-protein kinase Genghis Khan\tK16307 CDC42BP; serine\/threonine-protein kinase MRCK [EC:2.7.11.1]" }, { "name":"109433178 serine\/threonine-protein kinase Genghis Khan-like\tK16307 CDC42BP; serine\/threonine-protein kinase MRCK [EC:2.7.11.1]" }, { "name":"115257440 serine\/threonine-protein kinase Genghis Khan-like isoform X1\tK16307 CDC42BP; serine\/threonine-protein kinase MRCK [EC:2.7.11.1]" }, { "name":"109412517 LOW QUALITY PROTEIN: citron Rho-interacting kinase\tK16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]" }, { "name":"109420819 LOW QUALITY PROTEIN: citron Rho-interacting kinase-like\tK16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]" } ] }, { "name":"GRK family [OT]", "children":[ { "name":"109426380 G protein-coupled receptor kinase 1\tK00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]" }, { "name":"109403598 G protein-coupled receptor kinase 2 isoform X1\tK08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]" }, { "name":"109414765 G protein-coupled receptor kinase 2-like isoform X1\tK08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]" } ] }, { "name":"Other", "children":[ { "name":"109412949 serine\/threonine-protein kinase S6KL-like isoform X1\tK17529 SGK494; uncharacterized serine\/threonine-protein kinase SgK494 [EC:2.7.11.1]" } ] } ] }, { "name":"Serine\/threonine kinases: CAMK group", "children":[ { "name":"CAMK1 family [OT]", "children":[ { "name":"109415144 calcium\/calmodulin-dependent protein kinase type 1-like\tK08794 CAMK1; calcium\/calmodulin-dependent protein kinase I [EC:2.7.11.17]" }, { "name":"115266634 calcium\/calmodulin-dependent protein kinase type 1-like\tK08794 CAMK1; calcium\/calmodulin-dependent protein kinase I [EC:2.7.11.17]" } ] }, { "name":"CAMK2 family", "children":[ { "name":"109428414 calcium\/calmodulin-dependent protein kinase type II alpha chain\tK04515 CAMK2; calcium\/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]" } ] }, { "name":"CAMKL family", "children":[ { "name":"109407563 serine\/threonine-protein kinase BRSK2\tK08796 BRSK; BR serine\/threonine kinase [EC:2.7.11.1]" }, { "name":"109421007 serine\/threonine-protein kinase grp\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]" }, { "name":"109422342 MAP\/microtubule affinity-regulating kinase 3-like isoform X1\tK08798 MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]" }, { "name":"115253760 MAP\/microtubule affinity-regulating kinase 3-like isoform X1\tK08798 MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]" }, { "name":"109420458 MAP\/microtubule affinity-regulating kinase 3 isoform X1\tK16310 NIM1; serine\/threonine-protein kinase NIM1 [EC:2.7.11.1]" }, { "name":"109409696 PAS domain-containing serine\/threonine-protein kinase isoform X1\tK08801 PASK; PAS domain containing serine\/threonine kinase [EC:2.7.11.1]" }, { "name":"109404485 5'-AMP-activated protein kinase catalytic subunit alpha-2-like\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]" }, { "name":"109406304 LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase catalytic subunit alpha-2\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]" }, { "name":"115261487 LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase catalytic subunit alpha-2-like\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]" }, { "name":"109423725 serine\/threonine-protein kinase SIK3 isoform X1\tK19009 SIK3; serine\/threonine-protein kinase SIK3 [EC:2.7.11.1]" }, { "name":"109413893 serine\/threonine-protein kinase STK11\tK07298 STK11; serine\/threonine-protein kinase 11 [EC:2.7.11.1]" }, { "name":"109421110 LOW QUALITY PROTEIN: serine\/threonine-protein kinase STK11\tK07298 STK11; serine\/threonine-protein kinase 11 [EC:2.7.11.1]" } ] }, { "name":"DAPK family", "children":[ { "name":"109416786 serine\/threonine-protein kinase 17A\tK08804 STK17; serine\/threonine kinase 17 [EC:2.7.11.1]" }, { "name":"109428568 serine\/threonine-protein kinase 17A-like\tK08804 STK17; serine\/threonine kinase 17 [EC:2.7.11.1]" } ] }, { "name":"DCAMKL family", "children":[ { "name":"109427703 serine\/threonine-protein kinase GL21140 isoform X1\tK08805 DCLK1_2; doublecortin-like kinase 1\/2 [EC:2.7.11.1]" }, { "name":"115268764 serine\/threonine-protein kinase GL21140-like isoform X1\tK08805 DCLK1_2; doublecortin-like kinase 1\/2 [EC:2.7.11.1]" } ] }, { "name":"MAPKAPK family [OT]", "children":[ { "name":"109410610 MAP kinase-activated protein kinase 2-like\tK04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]" }, { "name":"109410728 MAP kinase-activated protein kinase 2\tK04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]" }, { "name":"109431109 serine\/threonine-protein kinase PKH2\tK04372 MKNK; MAP kinase interacting serine\/threonine kinase [EC:2.7.11.1]" } ] }, { "name":"MLCK family", "children":[ { "name":"109403665 myosin light chain kinase 2, skeletal\/cardiac muscle\tK00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]" }, { "name":"109407585 probable serine\/threonine-protein kinase pXi\tK00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]" }, { "name":"109407962 myosin light chain kinase 2, skeletal\/cardiac muscle-like\tK00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]" }, { "name":"109425849 LOW QUALITY PROTEIN: calcium\/calmodulin-dependent protein kinase type IV-like\tK00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]" }, { "name":"115254206 probable serine\/threonine-protein kinase MARK-C isoform X1\tK00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]" }, { "name":"109411811 LOW QUALITY PROTEIN: serine\/arginine repetitive matrix protein 1\tK12567 TTN; titin [EC:2.7.11.1]" }, { "name":"109411815 LOW QUALITY PROTEIN: titin\tK12567 TTN; titin [EC:2.7.11.1]" }, { "name":"109419627 titin-like isoform X1\tK12567 TTN; titin [EC:2.7.11.1]" }, { "name":"109419679 uncharacterized protein LOC109419679 isoform X1\tK12567 TTN; titin [EC:2.7.11.1]" }, { "name":"115265357 LOW QUALITY PROTEIN: serine\/arginine repetitive matrix protein 1-like\tK12567 TTN; titin [EC:2.7.11.1]" }, { "name":"115265359 uncharacterized protein LOC115265359 isoform X1\tK12567 TTN; titin [EC:2.7.11.1]" } ] }, { "name":"PHK family", "children":[ { "name":"109418342 phosphorylase b kinase gamma catalytic chain, skeletal muscle\/heart isoform isoform X1\tK00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]" }, { "name":"115253710 phosphorylase b kinase gamma catalytic chain, skeletal muscle\/heart isoform-like isoform X1\tK00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]" } ] }, { "name":"PIM family [OT]" }, { "name":"PKD family", "children":[ { "name":"109403520 serine\/threonine-protein kinase D1\tK06070 PKD; protein kinase D [EC:2.7.11.13]" } ] }, { "name":"PSK family" }, { "name":"RAD53 family", "children":[ { "name":"109407247 LOW QUALITY PROTEIN: ovarian-specific serine\/threonine-protein kinase Lok\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]" }, { "name":"109414315 ovarian-specific serine\/threonine-protein kinase Lok isoform X1\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]" }, { "name":"115258599 ovarian-specific serine\/threonine-protein kinase Lok-like isoform X1\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]" } ] }, { "name":"Trio family [OT]" }, { "name":"TSSK family", "children":[ { "name":"109408708 testis-specific serine\/threonine-protein kinase 6-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"109423806 testis-specific serine\/threonine-protein kinase 3-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"109425165 testis-specific serine\/threonine-protein kinase 1-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"109428915 testis-specific serine\/threonine-protein kinase 6-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"109430645 testis-specific serine\/threonine-protein kinase 3\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"115264992 testis-specific serine\/threonine-protein kinase 6-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"115265457 testis-specific serine\/threonine-protein kinase 3-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"115268322 testis-specific serine\/threonine-protein kinase 6-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" }, { "name":"115270935 testis-specific serine\/threonine-protein kinase 1-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]" } ] }, { "name":"CDPK family" }, { "name":"CASK family", "children":[ { "name":"109414936 LOW QUALITY PROTEIN: peripheral plasma membrane protein CASK\tK06103 CASK; calcium\/calmodulin-dependent serine protein kinase [EC:2.7.11.1]" }, { "name":"109414942 peripheral plasma membrane protein CASK isoform X1\tK06103 CASK; calcium\/calmodulin-dependent serine protein kinase [EC:2.7.11.1]" }, { "name":"109623069 LOW QUALITY PROTEIN: peripheral plasma membrane protein CASK-like\tK06103 CASK; calcium\/calmodulin-dependent serine protein kinase [EC:2.7.11.1]" } ] }, { "name":"Trbl family", "children":[ { "name":"109622876 tribbles homolog 2-like\tK08814 TRIB1_2; tribbles homolog 1\/2" }, { "name":"115258013 tribbles homolog 2-like\tK08814 TRIB1_2; tribbles homolog 1\/2" } ] }, { "name":"Other", "children":[ { "name":"109621378 serine\/threonine-protein kinase 40\tK16312 STK40; serine\/threonine-protein kinase 40 [EC:2.7.11.1]" } ] } ] }, { "name":"Serine\/threonine kinases: CK1 group", "children":[ { "name":"CK1 family [OT]", "children":[ { "name":"109415565 casein kinase I-like\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]" }, { "name":"109431105 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]" }, { "name":"115253826 casein kinase I-like\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]" }, { "name":"115256864 casein kinase I-like\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]" }, { "name":"109425583 casein kinase I isoform X1\tK08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]" }, { "name":"109421315 casein kinase I\tK08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]" }, { "name":"109621270 casein kinase I-like\tK08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]" } ] }, { "name":"TTBK family" }, { "name":"VRK family", "children":[ { "name":"109406620 nucleosomal histone kinase 1\tK08816 VRK; vaccinia related kinase [EC:2.7.11.1]" } ] } ] }, { "name":"Serine\/threonine kinases: CMGC group", "children":[ { "name":"CDK family", "children":[ { "name":"109416376 cyclin-dependent kinase 20-like\tK08817 CDK20; cyclin-dependent kinase 20 [EC:2.7.11.22]" }, { "name":"109430005 cyclin-dependent kinase 20-like\tK08817 CDK20; cyclin-dependent kinase 20 [EC:2.7.11.22]" }, { "name":"115267357 LOW QUALITY PROTEIN: cyclin-dependent kinase 20\tK08817 CDK20; cyclin-dependent kinase 20 [EC:2.7.11.22]" }, { "name":"109407622 serine\/threonine-protein kinase PITSLRE\tK08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]" }, { "name":"109429567 LOW QUALITY PROTEIN: cyclin-dependent kinase 1\tK02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109429984 cyclin-dependent kinase 1\tK02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109423610 cyclin-dependent kinase 2-like\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]" }, { "name":"115265092 cyclin-dependent kinase 2-like\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]" }, { "name":"115266510 cyclin-dependent kinase 2-like\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]" }, { "name":"109406441 cyclin-dependent kinase 4\tK02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]" }, { "name":"109411096 LOW QUALITY PROTEIN: cyclin-dependent kinase 5 homolog\tK02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]" }, { "name":"109398755 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109409323 cyclin-dependent kinase 8 isoform X1\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109419103 cyclin-dependent kinase 8 isoform X1\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]" }, { "name":"115254019 cyclin-dependent kinase 8 isoform X1\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109417667 cyclin-dependent kinase 9\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109622778 cyclin-dependent kinase 9-like\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109406061 cyclin-dependent kinase 10-like\tK02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]" }, { "name":"115265364 cyclin-dependent kinase 10-like\tK02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]" }, { "name":"109623260 LOW QUALITY PROTEIN: cyclin-dependent kinase 12\tK08819 CDK12_13; cyclin-dependent kinase 12\/13 [EC:2.7.11.22 2.7.11.23]" }, { "name":"109430891 LOW QUALITY PROTEIN: cyclin-dependent kinase 14\tK08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]" }, { "name":"115263167 cyclin-dependent kinase 14-like\tK08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]" } ] }, { "name":"MAPK family [OT]", "children":[ { "name":"109417712 mitogen-activated protein kinase 1-like\tK04371 ERK; mitogen-activated protein kinase 1\/3 [EC:2.7.11.24]" }, { "name":"109429565 stress-activated protein kinase JNK isoform X1\tK04440 JNK; mitogen-activated protein kinase 8\/9\/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]" }, { "name":"109429982 stress-activated protein kinase JNK isoform X1\tK04440 JNK; mitogen-activated protein kinase 8\/9\/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]" }, { "name":"109429983 stress-activated protein kinase JNK-like\tK04440 JNK; mitogen-activated protein kinase 8\/9\/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]" }, { "name":"109420146 mitogen-activated protein kinase p38b-like isoform X1\tK04441 P38; p38 MAP kinase [EC:2.7.11.24]" }, { "name":"109431243 mitogen-activated protein kinase p38b-like isoform X1\tK04441 P38; p38 MAP kinase [EC:2.7.11.24]" }, { "name":"115253754 LOW QUALITY PROTEIN: mitogen-activated protein kinase p38b-like\tK04441 P38; p38 MAP kinase [EC:2.7.11.24]" }, { "name":"109415878 serine\/threonine-protein kinase NLK2 isoform X1\tK04468 NLK; nemo like kinase [EC:2.7.11.24]" }, { "name":"109621282 serine\/threonine-protein kinase NLK-like isoform X1\tK04468 NLK; nemo like kinase [EC:2.7.11.24]" }, { "name":"115263318 serine\/threonine-protein kinase NLK-like isoform X1\tK04468 NLK; nemo like kinase [EC:2.7.11.24]" } ] }, { "name":"GSK family [OT]", "children":[ { "name":"109415782 protein kinase shaggy isoform X1\tK03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]" } ] }, { "name":"CLK family", "children":[ { "name":"109401879 LOW QUALITY PROTEIN: uncharacterized protein LOC109401879\tK08823 CLK2_3; dual specificity protein kinase CLK2\/3 [EC:2.7.12.1]" }, { "name":"109414708 uncharacterized protein LOC109414708 isoform X1\tK08823 CLK2_3; dual specificity protein kinase CLK2\/3 [EC:2.7.12.1]" }, { "name":"115267132 serine\/threonine-protein kinase Doa-like\tK08823 CLK2_3; dual specificity protein kinase CLK2\/3 [EC:2.7.12.1]" } ] }, { "name":"CDKL family", "children":[ { "name":"109622736 cyclin-dependent kinase-like 4 isoform X1\tK08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]" } ] }, { "name":"DYRK family [OT]", "children":[ { "name":"109402021 serine\/threonine-protein kinase minibrain-like isoform X1\tK08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]" }, { "name":"109413710 serine\/threonine-protein kinase minibrain isoform X1\tK08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]" }, { "name":"109401374 dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X3\tK18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]" }, { "name":"109415851 dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1\tK18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]" }, { "name":"109428701 homeodomain-interacting protein kinase 2-like isoform X1\tK08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]" }, { "name":"109424158 serine\/threonine-protein kinase PRP4 homolog isoform X1\tK08827 PRPF4B; serine\/threonine-protein kinase PRP4 [EC:2.7.11.1]" }, { "name":"109430828 serine\/threonine-protein kinase PRP4 homolog isoform X1\tK08827 PRPF4B; serine\/threonine-protein kinase PRP4 [EC:2.7.11.1]" } ] }, { "name":"RCK family [OT]", "children":[ { "name":"109414171 MAPK\/MAK\/MRK overlapping kinase-like\tK08830 RAGE; renal tumor antigen [EC:2.7.11.22]" } ] }, { "name":"SRPK family [OT]", "children":[ { "name":"109417954 SRSF protein kinase 3\tK15409 SRPK1; serine\/threonine-protein kinase SRPK1 [EC:2.7.11.1]" }, { "name":"109433278 SRSF protein kinase 3-like\tK08832 SRPK3; serine\/threonine-protein kinase SRPK3 [EC:2.7.11.1]" } ] } ] }, { "name":"Serine\/threonine kinases: STE group", "children":[ { "name":"STE7 family", "children":[ { "name":"109419297 dual specificity mitogen-activated protein kinase kinase dSOR1-like\tK04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]" }, { "name":"109426103 LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase dSOR1\tK04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]" }, { "name":"109431812 dual specificity mitogen-activated protein kinase kinase dSOR1\tK04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]" }, { "name":"115264449 dual specificity mitogen-activated protein kinase kinase dSOR1-like\tK04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]" }, { "name":"109431380 dual specificity mitogen-activated protein kinase kinase 6\tK04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]" }, { "name":"109407476 dual specificity mitogen-activated protein kinase kinase 4-like\tK04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]" }, { "name":"109419238 dual specificity mitogen-activated protein kinase kinase 4-like\tK04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]" }, { "name":"109399720 LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase hemipterous-like\tK04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]" }, { "name":"109402022 dual specificity mitogen-activated protein kinase kinase hemipterous isoform X1\tK04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]" }, { "name":"115254113 dual specificity mitogen-activated protein kinase kinase hemipterous-like isoform X1\tK04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]" } ] }, { "name":"STE20 family", "children":[ { "name":"109401264 LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 3-like\tK08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]" }, { "name":"109413626 LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 3\tK08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]" }, { "name":"109406566 LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 4\tK08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]" }, { "name":"109431038 LOW QUALITY PROTEIN: myosin-IIIa-like\tK08834 MYO3; myosin III [EC:2.7.11.1]" }, { "name":"109432976 LOW QUALITY PROTEIN: myosin-IIIb-like\tK08834 MYO3; myosin III [EC:2.7.11.1]" }, { "name":"109621667 neither inactivation nor afterpotential protein C-like\tK08834 MYO3; myosin III [EC:2.7.11.1]" }, { "name":"109423080 serine\/threonine-protein kinase OSR1\tK08835 OXSR1; serine\/threonine-protein kinase OSR1\/STK39 [EC:2.7.11.1]" }, { "name":"109405050 LOW QUALITY PROTEIN: serine\/threonine-protein kinase pak-1\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]" }, { "name":"109622061 serine\/threonine-protein kinase pak-1-like\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]" }, { "name":"115254232 serine\/threonine-protein kinase PAK 1-like isoform X1\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]" }, { "name":"109401286 LOW QUALITY PROTEIN: serine\/threonine-protein kinase PAK mbt\tK05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]" }, { "name":"109412916 serine\/threonine-protein kinase 10-like\tK08836 SLK; STE20-like kinase [EC:2.7.11.1]" }, { "name":"109418688 serine\/threonine-protein kinase 10-like isoform X1\tK08836 SLK; STE20-like kinase [EC:2.7.11.1]" }, { "name":"109429438 STE20-related kinase adapter protein alpha-like\tK08271 STRADA; STE20-related kinase adapter protein alpha" }, { "name":"109397924 serine\/threonine-protein kinase 3\tK04412 STK3; serine\/threonine kinase 3" }, { "name":"109418980 serine\/threonine-protein kinase 3-like\tK04412 STK3; serine\/threonine kinase 3" }, { "name":"109404231 germinal center kinase 1 isoform X1\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]" }, { "name":"109431002 serine\/threonine-protein kinase svkA-like isoform X1\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]" }, { "name":"115253628 LOW QUALITY PROTEIN: serine\/threonine-protein kinase svkA-like\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]" }, { "name":"115253704 serine\/threonine-protein kinase svkA-like\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]" }, { "name":"109423376 LOW QUALITY PROTEIN: serine\/threonine-protein kinase Tao\tK04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]" }, { "name":"109430466 serine\/threonine-protein kinase Tao-like isoform X1\tK04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]" } ] }, { "name":"STE11 family", "children":[ { "name":"109430716 mitogen-activated protein kinase kinase kinase 4 isoform X1\tK04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]" }, { "name":"115269543 LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 15-like\tK04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]" } ] }, { "name":"Other" } ] }, { "name":"Serine\/threonine kinases: TKL group", "children":[ { "name":"IRAK family", "children":[ { "name":"109415475 serine\/threonine-protein kinase pelle-like\tK04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]" }, { "name":"115264543 serine\/threonine-protein kinase pelle-like\tK04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]" }, { "name":"115264679 serine\/threonine-protein kinase pelle-like\tK04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]" }, { "name":"109412409 interleukin-1 receptor-associated kinase 4-like\tK04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]" } ] }, { "name":"LISK family [OT]", "children":[ { "name":"109405105 LIM domain kinase 1 isoform X1\tK05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]" } ] }, { "name":"LRRK family" }, { "name":"MLK family", "children":[ { "name":"109421877 LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 7-like\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]" }, { "name":"109425252 LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 7\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]" }, { "name":"115254050 mitogen-activated protein kinase kinase kinase 7-like\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]" }, { "name":"109406884 LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 11-like\tK04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]" }, { "name":"109425664 mitogen-activated protein kinase kinase kinase 9 isoform X1\tK04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]" }, { "name":"109400747 integrin-linked protein kinase\tK06272 ILK; integrin-linked kinase [EC:2.7.11.1]" } ] }, { "name":"RAF family [OT]", "children":[ { "name":"109418642 LOW QUALITY PROTEIN: raf homolog serine\/threonine-protein kinase Raf-like\tK04365 BRAF; B-Raf proto-oncogene serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"109621965 kinase suppressor of Ras 2-like isoform X1\tK18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]" } ] }, { "name":"RIPK family [OT]" }, { "name":"Other" } ] }, { "name":"Serine\/threonine kinases: Other", "children":[ { "name":"RGC family [OT]", "children":[ { "name":"109412673 atrial natriuretic peptide receptor 1-like isoform X1\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]" }, { "name":"109416838 atrial natriuretic peptide receptor 1\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]" }, { "name":"109420919 LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]" }, { "name":"109400375 LOW QUALITY PROTEIN: retinal guanylyl cyclase 2-like\tK12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]" }, { "name":"109432406 retinal guanylyl cyclase 2-like isoform X1\tK12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]" }, { "name":"115269209 LOW QUALITY PROTEIN: retinal guanylyl cyclase 2-like\tK12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]" } ] }, { "name":"BUB family", "children":[ { "name":"109402802 LOW QUALITY PROTEIN: mitotic checkpoint serine\/threonine-protein kinase BUB1-like\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"109404490 LOW QUALITY PROTEIN: uncharacterized protein LOC109404490\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"109406321 uncharacterized protein LOC109406321\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"109422630 LOW QUALITY PROTEIN: uncharacterized protein LOC109422630\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"115265119 LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D-like\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"115271077 LOW QUALITY PROTEIN: uncharacterized protein LOC115271077\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]" } ] }, { "name":"Bud32 family", "children":[ { "name":"109418127 EKC\/KEOPS complex subunit bud32-like\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]" } ] }, { "name":"CAMKK family", "children":[ { "name":"109402816 calcium\/calmodulin-dependent protein kinase kinase 1\tK07359 CAMKK2; calcium\/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]" }, { "name":"109422598 calcium\/calmodulin-dependent protein kinase kinase 1-like isoform X1\tK07359 CAMKK2; calcium\/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]" }, { "name":"115259223 calcium\/calmodulin-dependent protein kinase kinase 1-like\tK07359 CAMKK2; calcium\/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]" } ] }, { "name":"CDC7 family", "children":[ { "name":"109409567 probable cell division control protein 7 homolog 2\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]" }, { "name":"115268243 probable cell division control protein 7 homolog 2\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]" } ] }, { "name":"CK2 family", "children":[ { "name":"109402166 casein kinase II subunit alpha\tK03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]" }, { "name":"109413239 casein kinase II subunit alpha\tK03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]" } ] }, { "name":"Haspin family" }, { "name":"IKK family [OT]", "children":[ { "name":"109419873 inhibitor of nuclear factor kappa-B kinase subunit alpha-like\tK07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]" }, { "name":"115271052 LOW QUALITY PROTEIN: inhibitor of nuclear factor kappa-B kinase subunit alpha-like\tK07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]" }, { "name":"109420658 serine\/threonine-protein kinase TBK1\tK05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]" } ] }, { "name":"IRE family", "children":[ { "name":"109426214 serine\/threonine-protein kinase\/endoribonuclease IRE1\tK08852 ERN1; serine\/threonine-protein kinase\/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]" } ] }, { "name":"MOS family", "children":[ { "name":"109408572 dual specificity protein kinase zak2\tK04367 MOS; proto-oncogene serine\/threonine-protein kinase mos [EC:2.7.11.1]" }, { "name":"109622494 dual specificity protein kinase zakA\tK04367 MOS; proto-oncogene serine\/threonine-protein kinase mos [EC:2.7.11.1]" } ] }, { "name":"NAK family [OT]", "children":[ { "name":"109410077 BMP-2-inducible protein kinase-like isoform X1\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]" }, { "name":"109422750 uncharacterized protein LOC109422750\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]" }, { "name":"109430219 BMP-2-inducible protein kinase-like isoform X1\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]" }, { "name":"109431833 uncharacterized protein LOC109431833\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]" }, { "name":"109429313 cyclin-G-associated kinase-like\tK08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]" }, { "name":"115259642 LOW QUALITY PROTEIN: cyclin-G-associated kinase-like\tK08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]" } ] }, { "name":"NEK family", "children":[ { "name":"109417615 serine\/threonine-protein kinase Nek8\tK20877 NEK8; serine\/threonine-protein kinase Nek8 [EC:2.7.11.1]" } ] }, { "name":"NKF1 family", "children":[ { "name":"109408712 serine\/threonine-protein kinase meng-po-like\tK08858 SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]" }, { "name":"109428919 serine\/threonine-protein kinase meng-po-like\tK08858 SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]" } ] }, { "name":"NKF2 family", "children":[ { "name":"109404477 uncharacterized protein LOC109404477\tK05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]" }, { "name":"109406292 uncharacterized protein LOC109406292\tK05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]" } ] }, { "name":"NKF3 family" }, { "name":"NKF4 family" }, { "name":"NKF5 family" }, { "name":"NRBP family", "children":[ { "name":"109420353 nuclear receptor-binding protein isoform X1\tK08875 NRBP; nuclear receptor-binding protein" } ] }, { "name":"PEK family [OT]", "children":[ { "name":"109432321 eukaryotic translation initiation factor 2-alpha kinase 1-like\tK16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]" }, { "name":"109418329 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 2-alpha kinase-like\tK08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]" }, { "name":"109427298 eukaryotic translation initiation factor 2-alpha kinase-like\tK08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]" }, { "name":"109397123 eIF-2-alpha kinase GCN2\tK16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]" } ] }, { "name":"PLK family [OT]", "children":[ { "name":"109429192 serine\/threonine-protein kinase polo-like isoform X1\tK06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]" }, { "name":"109623259 serine\/threonine-protein kinase PLK4\tK08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]" } ] }, { "name":"SCY1 family [OT]", "children":[ { "name":"109410127 N-terminal kinase-like protein isoform X1\tK08876 SCYL1; SCY1-like protein 1" }, { "name":"109427410 N-terminal kinase-like protein isoform X1\tK08876 SCYL1; SCY1-like protein 1" }, { "name":"109430837 SCY1-like protein 2\tK17541 SCYL2; SCY1-like protein 2" }, { "name":"109431423 SCY1-like protein 2\tK17541 SCYL2; SCY1-like protein 2" }, { "name":"115263194 SCY1-like protein 2\tK17541 SCYL2; SCY1-like protein 2" }, { "name":"115263213 SCY1-like protein 2\tK17541 SCYL2; SCY1-like protein 2" }, { "name":"109414266 protein-associating with the carboxyl-terminal domain of ezrin-like\tK17542 SCYL3; SCY1-like protein 3" }, { "name":"109420699 protein-associating with the carboxyl-terminal domain of ezrin\tK17542 SCYL3; SCY1-like protein 3" }, { "name":"115255130 protein-associating with the carboxyl-terminal domain of ezrin-like\tK17542 SCYL3; SCY1-like protein 3" } ] }, { "name":"Slob family", "children":[ { "name":"109404817 uncharacterized protein LOC109404817 isoform X1\tK17543 PXK; PX domain-containing protein kinase-like protein" }, { "name":"109423925 uncharacterized protein LOC109423925 isoform X1\tK17543 PXK; PX domain-containing protein kinase-like protein" }, { "name":"109430545 PX domain-containing protein kinase-like protein\tK17543 PXK; PX domain-containing protein kinase-like protein" } ] }, { "name":"TBCK family", "children":[ { "name":"109427434 TBC domain-containing protein kinase-like protein\tK17544 TBCK; TBC domain-containing protein kinase-like protein" } ] }, { "name":"TLK family", "children":[ { "name":"109422130 serine\/threonine-protein kinase tousled-like 2 isoform X1\tK08864 TLK; tousled-like kinase [EC:2.7.11.1]" } ] }, { "name":"TOPK family", "children":[ { "name":"109397203 lymphokine-activated killer T-cell-originated protein kinase homolog\tK08865 PBK; PDZ-binding kinase [EC:2.7.12.2]" }, { "name":"109432624 lymphokine-activated killer T-cell-originated protein kinase-like\tK08865 PBK; PDZ-binding kinase [EC:2.7.12.2]" } ] }, { "name":"TTK family", "children":[ { "name":"109415993 LOW QUALITY PROTEIN: dual specificity protein kinase Ttk\tK08866 TTK; serine\/threonine-protein kinase TTK\/MPS1 [EC:2.7.12.1]" } ] }, { "name":"ULK family [OT]", "children":[ { "name":"109416096 LOW QUALITY PROTEIN: serine\/threonine-protein kinase fused-like\tK06228 FU; fused [EC:2.7.11.1]" }, { "name":"109409885 serine\/threonine-protein kinase unc-51 isoform X1\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]" }, { "name":"109428482 serine\/threonine-protein kinase ULK3\tK21358 ULK3; serine\/threonine-protein kinase ULK3 [EC:2.7.11.1]" } ] }, { "name":"VPS15 family", "children":[ { "name":"109397598 LOW QUALITY PROTEIN: phosphoinositide 3-kinase regulatory subunit 4-like\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]" }, { "name":"109422874 phosphoinositide 3-kinase regulatory subunit 4\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]" } ] }, { "name":"WEE family", "children":[ { "name":"109413663 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase\tK06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]" }, { "name":"109401434 wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]" }, { "name":"109404654 wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]" } ] }, { "name":"Wnk family", "children":[ { "name":"109424682 LOW QUALITY PROTEIN: uncharacterized protein LOC109424682\tK08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]" } ] }, { "name":"ABC1 family", "children":[ { "name":"109397847 uncharacterized aarF domain-containing protein kinase 5\tK08869 ADCK; aarF domain-containing kinase" }, { "name":"109400860 atypical kinase COQ8B, mitochondrial-like\tK08869 ADCK; aarF domain-containing kinase" }, { "name":"109415487 LOW QUALITY PROTEIN: atypical kinase COQ8B, mitochondrial\tK08869 ADCK; aarF domain-containing kinase" }, { "name":"109418972 uncharacterized aarF domain-containing protein kinase 5-like\tK08869 ADCK; aarF domain-containing kinase" }, { "name":"109426430 uncharacterized aarF domain-containing protein kinase 1\tK08869 ADCK; aarF domain-containing kinase" } ] }, { "name":"Alpha family [OT]" }, { "name":"BCR family" }, { "name":"BRD family [OT]", "children":[ { "name":"109398784 LOW QUALITY PROTEIN: homeotic protein female sterile\tK11722 BRD4; bromodomain-containing protein 4" }, { "name":"109429154 LOW QUALITY PROTEIN: homeotic protein female sterile-like\tK11722 BRD4; bromodomain-containing protein 4" } ] }, { "name":"FAST family" }, { "name":"G11 family" }, { "name":"H11 family" }, { "name":"PDHK family [OT]", "children":[ { "name":"109414459 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial isoform X1\tK00898 PDK2_3_4; pyruvate dehydrogenase kinase 2\/3\/4 [EC:2.7.11.2]" }, { "name":"109621250 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial-like isoform X1\tK00898 PDK2_3_4; pyruvate dehydrogenase kinase 2\/3\/4 [EC:2.7.11.2]" }, { "name":"115266328 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial-like isoform X1\tK00898 PDK2_3_4; pyruvate dehydrogenase kinase 2\/3\/4 [EC:2.7.11.2]" } ] }, { "name":"PIKK family [OT]", "children":[ { "name":"109400978 serine\/threonine-protein kinase ATM-like\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]" }, { "name":"109408234 serine\/threonine-protein kinase ATM-like\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]" }, { "name":"109397767 LOW QUALITY PROTEIN: serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]" }, { "name":"109428788 LOW QUALITY PROTEIN: serine\/threonine-protein kinase ATR-like\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]" }, { "name":"115257227 serine\/threonine-protein kinase ATR-like\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]" }, { "name":"115269406 LOW QUALITY PROTEIN: serine\/threonine-protein kinase ATR-like\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]" }, { "name":"109429896 serine\/threonine-protein kinase Tor\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]" }, { "name":"109414486 DNA-dependent protein kinase catalytic subunit-like\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]" }, { "name":"109427666 LOW QUALITY PROTEIN: serine\/threonine-protein kinase Smg1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"115260732 serine\/threonine-protein kinase Smg1-like isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"109424534 transcription-associated protein 1-like\tK08874 TRRAP; transformation\/transcription domain-associated protein" }, { "name":"109428757 LOW QUALITY PROTEIN: transcription-associated protein 1\tK08874 TRRAP; transformation\/transcription domain-associated protein" } ] }, { "name":"RIO family [OT]", "children":[ { "name":"109407710 LOW QUALITY PROTEIN: serine\/threonine-protein kinase RIO1\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]" }, { "name":"109431291 serine\/threonine-protein kinase RIO1-like isoform X1\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]" }, { "name":"115258247 LOW QUALITY PROTEIN: serine\/threonine-protein kinase RIO1-like\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]" }, { "name":"109415977 serine\/threonine-protein kinase rio2\tK07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]" }, { "name":"109433258 LOW QUALITY PROTEIN: serine\/threonine-protein kinase RIO3\tK08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]" } ] }, { "name":"TAF1 family", "children":[ { "name":"109415553 transcription initiation factor TFIID subunit 1 isoform X1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]" } ] }, { "name":"TIF1 family [OT]", "children":[ { "name":"109410890 E3 ubiquitin-protein ligase TRIM33 isoform X1\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]" }, { "name":"115254065 E3 ubiquitin-protein ligase TRIM33-like\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]" } ] }, { "name":"Other", "children":[ { "name":"109422375 protein mahjong isoform X1\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]" } ] }, { "name":"Bacterial family" } ] }, { "name":"Receptor serine\/threonine kinases (RSTK): TKL group", "children":[ { "name":"TGFBR1 family [OT]", "children":[ { "name":"109423295 activin receptor type-1 isoform X1\tK04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]" }, { "name":"109404788 bone morphogenetic protein receptor type-1B-like\tK13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]" }, { "name":"109423928 bone morphogenetic protein receptor type-1B-like isoform X1\tK13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]" }, { "name":"109415848 TGF-beta receptor type-1 isoform X1\tK04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]" } ] }, { "name":"TGFBR2 family [OT]", "children":[ { "name":"109401899 activin receptor type-2B-like\tK13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]" }, { "name":"109414694 activin receptor type-2B-like\tK13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]" }, { "name":"109403780 bone morphogenetic protein receptor type-2-like\tK04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]" }, { "name":"109406024 bone morphogenetic protein receptor type-2-like\tK04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]" } ] } ] }, { "name":"Receptor tyrosine kinases (RTK)", "children":[ { "name":"EGFR family [OT]", "children":[ { "name":"109427537 LOW QUALITY PROTEIN: epidermal growth factor receptor\tK04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]" }, { "name":"115266987 LOW QUALITY PROTEIN: epidermal growth factor receptor-like\tK04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]" } ] }, { "name":"INSR family [OT]" }, { "name":"PDGFR family [OT]" }, { "name":"FGFR family [OT]", "children":[ { "name":"109408989 LOW QUALITY PROTEIN: tyrosine kinase receptor Cad96Ca-like\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]" }, { "name":"109426492 LOW QUALITY PROTEIN: tyrosine kinase receptor Cad96Ca-like\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]" } ] }, { "name":"VEGFR family [OT]", "children":[ { "name":"109415159 vascular endothelial growth factor receptor 1-like isoform X1\tK05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]" }, { "name":"109417728 vascular endothelial growth factor receptor 1 isoform X1\tK05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]" } ] }, { "name":"MET family" }, { "name":"TRK family [OT]" }, { "name":"EPH family [OT]", "children":[ { "name":"109433627 ephrin type-A receptor 7 isoform X1\tK05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]" }, { "name":"115253530 ephrin type-A receptor 3-like\tK05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]" }, { "name":"115269286 ephrin type-A receptor 3-like\tK05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]" } ] }, { "name":"AXL family" }, { "name":"ALK family", "children":[ { "name":"109422212 ALK tyrosine kinase receptor\tK05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]" } ] }, { "name":"TIE family" }, { "name":"ROR family", "children":[ { "name":"109403057 tyrosine-protein kinase transmembrane receptor Ror\tK05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]" } ] }, { "name":"DDR family", "children":[ { "name":"109427861 discoidin domain-containing receptor 2 isoform X1\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]" } ] }, { "name":"RET family", "children":[ { "name":"109420544 proto-oncogene tyrosine-protein kinase receptor Ret isoform X1\tK05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]" }, { "name":"109621254 uncharacterized protein LOC109621254\tK05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]" } ] }, { "name":"ROS family", "children":[ { "name":"109397197 proto-oncogene tyrosine-protein kinase ROS-like isoform X1\tK05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]" }, { "name":"109432609 proto-oncogene tyrosine-protein kinase ROS-like isoform X1\tK05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]" } ] }, { "name":"CCK family", "children":[ { "name":"109433505 tyrosine-protein kinase-like otk\tK05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]" } ] }, { "name":"RYK family", "children":[ { "name":"109403065 tyrosine-protein kinase Dnt\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]" }, { "name":"109420679 tyrosine-protein kinase Dnt-like\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]" }, { "name":"109623182 tyrosine-protein kinase Dnt-like\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]" }, { "name":"115256167 tyrosine-protein kinase RYK-like\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]" }, { "name":"115269910 tyrosine-protein kinase RYK-like\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]" } ] }, { "name":"MUSK family", "children":[ { "name":"109423779 LOW QUALITY PROTEIN: tyrosine-protein kinase transmembrane receptor Ror2-like\tK05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]" }, { "name":"109430598 tyrosine-protein kinase transmembrane receptor Ror2\tK05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]" }, { "name":"115254242 tyrosine-protein kinase transmembrane receptor Ror2-like\tK05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]" } ] }, { "name":"LMR family [OT]" } ] }, { "name":"Non-receptor tyrosine kinases", "children":[ { "name":"ABL family", "children":[ { "name":"109408571 tyrosine-protein kinase Abl\tK06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]" }, { "name":"109423868 LOW QUALITY PROTEIN: tyrosine-protein kinase Abl-like\tK06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]" } ] }, { "name":"ACK family", "children":[ { "name":"109408773 LOW QUALITY PROTEIN: uncharacterized protein LOC109408773\tK08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]" }, { "name":"109432681 LOW QUALITY PROTEIN: uncharacterized protein LOC109432681\tK08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]" } ] }, { "name":"CSK family", "children":[ { "name":"109417380 trithorax group protein osa-like isoform X1\tK05728 CSK; C-terminal Src kinase [EC:2.7.10.4]" } ] }, { "name":"FAK family", "children":[ { "name":"109401644 uncharacterized protein LOC109401644 isoform X1\tK05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]" } ] }, { "name":"FES family", "children":[ { "name":"109411496 tyrosine-protein kinase Fer isoform X2\tK08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]" }, { "name":"109415932 tyrosine-protein kinase Fer-like isoform X1\tK08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]" }, { "name":"115260434 LOW QUALITY PROTEIN: tyrosine-protein kinase Fer-like\tK08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]" } ] }, { "name":"JAK family [OT]", "children":[ { "name":"109419906 tyrosine-protein kinase hopscotch\tK04447 JAK2; Janus kinase 2 [EC:2.7.10.2]" } ] }, { "name":"SRC family", "children":[ { "name":"109399285 tyrosine-protein kinase Src64B\tK05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]" } ] }, { "name":"TEC family", "children":[ { "name":"109423693 LOW QUALITY PROTEIN: tyrosine-protein kinase Btk29A-like\tK07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]" } ] }, { "name":"SYK family", "children":[ { "name":"109413096 LOW QUALITY PROTEIN: tyrosine-protein kinase Shark\tK17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]" }, { "name":"109418536 tyrosine-protein kinase Shark-like isoform X1\tK17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]" } ] }, { "name":"Other" }, { "name":"Bacterial" } ] }, { "name":"Histidine kinases", "children":[ { "name":"OmpR family" }, { "name":"NarL family" }, { "name":"Spo family [OT]" }, { "name":"CitB family [OT]" }, { "name":"LytTR family [OT]" }, { "name":"NtrC family" }, { "name":"CheA family [OT]" }, { "name":"Cell cycle family [OT]" }, { "name":"Lux family [OT]" }, { "name":"LuxR family [OT]" }, { "name":"Other" } ] } ] }