{
	"name":"aan03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"D7S_01964 double-stranded RNA-binding protein\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"D7S_02311 oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"D7S_01963 GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"D7S_00664 obgE; GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"D7S_00328 molecular chaperone DnaK\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"D7S_00352 nusA; transcription elongation factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"D7S_02386 antitermination protein NusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"D7S_01711 nusG; transcription antiterminator NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"D7S_01933 16S rRNA pseudouridylate synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"D7S_01132 ribosomal RNA small subunit methyltransferase A\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"D7S_03450 16S rRNA methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"D7S_00611 MFS transporter\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"D7S_01751 16S rRNA methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"D7S_01023 16S rRNA methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"D7S_01234 16S rRNA methyltransferase\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"D7S_01473 16S rRNA methyltransferase\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"D7S_00456 tetrapyrrole methylase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"D7S_01599 DNA polymerase I\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"D7S_00843 23S rRNA methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"D7S_00142 rrmJ; 23S rRNA methyltransferase\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"D7S_01193 50S rRNA methyltransferase\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"D7S_01095 ribosomal RNA large subunit methyltransferase J\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"D7S_01500 rlmL; 23S rRNA methyltransferase\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"D7S_00231 ribosomal RNA large subunit methyltransferase M\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"D7S_01891 ribosomal RNA large subunit methyltransferase N\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"D7S_01064 23S rRNA methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"D7S_01654 23S rRNA pseudouridylate synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"D7S_02357 pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"D7S_00304 23S rRNA pseudouridylate synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"D7S_00684 23S rRNA pseudouridylate synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"D7S_00829 rluD; 23S rRNA pseudouridylate synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"D7S_01578 pseudouridine synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"D7S_00866 rRNA methyltransferase\tK03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"D7S_00614 alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"D7S_00570 ribosomal protein S6 modification protein\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"D7S_00836 rimM; 16S rRNA-processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"D7S_01794 rimO; ribosomal protein S12 methylthiotransferase\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"D7S_00436 hypothetical protein\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor"
			},
			{
				"name":"D7S_01674 prmA; ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"D7S_02103 50S ribosomal protein L30\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"D7S_02035 hypothetical protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"D7S_01964 double-stranded RNA-binding protein\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"D7S_00682 ribonuclease E\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"D7S_02066 ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"D7S_01025 Holliday junction resolvase\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"D7S_01729 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"D7S_01650 ATP-dependent RNA helicase SrmB\tK05590 srmB; ATP-dependent RNA helicase SrmB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"D7S_01963 GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"D7S_02312 GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"D7S_02060 GTP-binding protein Der\tK03977 engA; GTPase"
			},
			{
				"name":"D7S_00664 obgE; GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"D7S_00946 tRNA threonylcarbamoyladenosine biosynthesis protein RimN\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"D7S_01777 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"D7S_00350 rbfA; ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"D7S_00353 ribosome maturation protein RimP\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"D7S_01192 ribosome-associated protein IOJAP\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"D7S_01459 metal-binding heat shock protein\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"D7S_02223 RNA-binding protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"D7S_01737 hypothetical protein\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"D7S_01679 ribosome-associated inhibitor A\tK05809 raiA; ribosome-associated inhibitor A"
			},
			{
				"name":"D7S_01844 ychF; GTP-binding protein\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"D7S_01181 hypothetical protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}