{
	"name":"abac04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"LuPra_00520 eno; Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"LuPra_05060 gap1; Glyceraldehyde-3-phosphate dehydrogenase 1\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"LuPra_05061 pgk; Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"LuPra_05725 pyk; Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"LuPra_05630 cypB; Peptidyl-prolyl cis-trans isomerase B\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
			},
			{
				"name":"LuPra_00710 Membrane dipeptidase (Peptidase family M19)\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"LuPra_03583 Membrane dipeptidase (Peptidase family M19)\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"LuPra_05220 putative metal-dependent hydrolase of the TIM-barrel fold protein\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"LuPra_05881 Membrane dipeptidase (Peptidase family M19)\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"LuPra_00129 yqiK; Inner membrane protein YqiK\tK07192 FLOT; flotillin"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"LuPra_04242 groL; Stress protein H5\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"LuPra_04475 dnaK; Heat shock protein 70\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"LuPra_02955 pgi; Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"LuPra_01845 ptpA_4; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"LuPra_04284 ptpA_6; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"LuPra_01782 gnl; Gluconolactonase precursor\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
			},
			{
				"name":"LuPra_03460 guaB; Inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"LuPra_04881 tuf_1; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"LuPra_04899 tuf_2; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"LuPra_03991 yloB_2; Calcium-transporting ATPase\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			},
			{
				"name":"LuPra_05821 HIT-like protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells",
			"children":[
			{
				"name":"LuPra_01845 ptpA_4; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"LuPra_04284 ptpA_6; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			}
			]
		},
		{
			"name":"Exosomal proteins of hepatic cells"
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"LuPra_03017 Long-chain-fatty-acid--CoA ligase FadD15\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"LuPra_05585 lcfB_3; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"LuPra_05606 lcfB_4; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"LuPra_00040 56kDa selenium binding protein (SBP56)\tK17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"LuPra_04242 groL; Stress protein H5\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"LuPra_03382 thlA_1; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"LuPra_03723 thlA_2; Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"LuPra_00431 Angiotensin-converting enzyme\tK01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]"
			},
			{
				"name":"LuPra_03588 ahcY; Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"LuPra_04858 adk; Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"LuPra_03681 apt; Adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"LuPra_00466 argH1; Argininosuccinate lyase 1\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"LuPra_00734 argH; Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"LuPra_00733 argG_1; Argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"LuPra_05410 argG_2; Argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"LuPra_03991 yloB_2; Calcium-transporting ATPase\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			},
			{
				"name":"LuPra_04062 metC; Cystathionine beta-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
			},
			{
				"name":"LuPra_01477 N(G),N(G)-dimethylarginine dimethylaminohydrolase\tK01482 DDAH; dimethylargininase [EC:3.5.3.18]"
			},
			{
				"name":"LuPra_00260 ddc_1; L-2,4-diaminobutyrate decarboxylase\tK01593 DDC; aromatic-L-amino-acid\/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]"
			},
			{
				"name":"LuPra_06070 ddc_2; L-2,4-diaminobutyrate decarboxylase\tK01593 DDC; aromatic-L-amino-acid\/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]"
			},
			{
				"name":"LuPra_00915 D-hydantoinase\tK01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]"
			},
			{
				"name":"LuPra_03284 fumarylacetoacetase\tK01555 FAH; fumarylacetoacetase [EC:3.7.1.2]"
			},
			{
				"name":"LuPra_02910 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
			},
			{
				"name":"LuPra_06075 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
			},
			{
				"name":"LuPra_04304 galK; Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
			},
			{
				"name":"LuPra_01079 glgB; 1,4-alpha-glucan branching enzyme GlgB\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
			},
			{
				"name":"LuPra_01139 glpK; Glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"LuPra_03568 glnA_1; Glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"LuPra_06186 glnA_2; Glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"LuPra_02955 pgi; Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"LuPra_05952 hemB; Delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"LuPra_03282 hpd; 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"LuPra_03932 Putative pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"LuPra_06063 Putative pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"LuPra_01282 phoA_1; Alkaline phosphatase 4 precursor\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"LuPra_01283 phoA_2; Alkaline phosphatase 4 precursor\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"LuPra_01910 serA_1; D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"LuPra_03218 serA_2; D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"LuPra_04928 purH; Bifunctional purine biosynthesis protein PurH\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"LuPra_03017 Long-chain-fatty-acid--CoA ligase FadD15\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"LuPra_05585 lcfB_3; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"LuPra_05606 lcfB_4; Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"LuPra_04691 lpdA; Dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"LuPra_06037 lpdG; Dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"LuPra_04422 etfA; Electron transfer flavoprotein large subunit\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"LuPra_02956 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"LuPra_03460 guaB; Inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"LuPra_04475 dnaK; Heat shock protein 70\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"LuPra_04242 groL; Stress protein H5\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"LuPra_04881 tuf_1; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"LuPra_04899 tuf_2; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"LuPra_04242 groL; Stress protein H5\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"LuPra_02955 pgi; Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"LuPra_01845 ptpA_4; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"LuPra_04284 ptpA_6; Prolyl tripeptidyl peptidase precursor\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"LuPra_02956 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"LuPra_04475 dnaK; Heat shock protein 70\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"LuPra_05062 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"LuPra_04881 tuf_1; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"LuPra_04899 tuf_2; Elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"LuPra_03991 yloB_2; Calcium-transporting ATPase\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"LuPra_04242 groL; Stress protein H5\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"LuPra_02956 zwf; Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"LuPra_03991 yloB_2; Calcium-transporting ATPase\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			},
			{
				"name":"LuPra_05062 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"LuPra_05062 tpiA; Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}