{
	"name":"aci02044",
	"children":[
	{
		"name":"Type I secretion system",
		"children":[
		{
			"name":"alpha-Hemolysin\/cyclolysin transporter",
			"children":[
			{
				"name":"ACIAD0278 tolC; channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"ACIAD2648 conserved hypothetical protein; putative outer membrane efflux protein\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"RTX toxin transporter",
			"children":[
			{
				"name":"ACIAD0278 tolC; channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"ACIAD2648 conserved hypothetical protein; putative outer membrane efflux protein\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Multiple protein transporter",
			"children":[
			{
				"name":"ACIAD0278 tolC; channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"ACIAD2648 conserved hypothetical protein; putative outer membrane efflux protein\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Adhesin protein transporter",
			"children":[
			{
				"name":"ACIAD1488 putative protein secretion efflux system (ABC superfamily, atp_bind and membrane)\tK12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB"
			},
			{
				"name":"ACIAD1489 putative protein secretion efflux system, membrane fusion protein (hemolysin-type secretion transmembrane protein) (superfamily ABC, membrane)\tK12542 lapC; membrane fusion protein, adhesin transport system"
			},
			{
				"name":"ACIAD1487 putative outer membrane efflux protein, type I secretion protein\tK12543 lapE; outer membrane protein, adhesin transport system"
			}
			]
		},
		{
			"name":"RaxAB-RaxC type I secretion system protein",
			"children":[
			{
				"name":"ACIAD0278 tolC; channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"ACIAD2648 conserved hypothetical protein; putative outer membrane efflux protein\tK12340 tolC; outer membrane protein"
			}
			]
		}
		]
	},
	{
		"name":"Type II secretion system",
		"children":[
		{
			"name":"General secretion pathway protein",
			"children":[
			{
				"name":"ACIAD0293 putative general secretion pathway protein\tK02452 gspC; general secretion pathway protein C"
			},
			{
				"name":"ACIAD0294 putative general secretion pathway protein\tK02453 gspD; general secretion pathway protein D"
			},
			{
				"name":"ACIAD2241 putative secretion pathway ATPase\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]"
			},
			{
				"name":"ACIAD3024 xcpR; general secretion pathway protein E (Type II traffic warden ATPase)\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]"
			},
			{
				"name":"ACIAD0411 xcpS; general secretion pathway protein F\tK02455 gspF; general secretion pathway protein F"
			},
			{
				"name":"ACIAD0412 xcpT; general secretion pathway protein G\tK02456 gspG; general secretion pathway protein G"
			},
			{
				"name":"ACIAD2357 putative general secretion pathway protein G precursor\tK02456 gspG; general secretion pathway protein G"
			},
			{
				"name":"ACIAD2356 xcpV; general secretion pathway protein I precursor (PilD-dependent protein pddC)\tK02458 gspI; general secretion pathway protein I"
			},
			{
				"name":"ACIAD2355 xcpW; general secretion pathway protein J precursor (PilD-dependent protein pddD)\tK02459 gspJ; general secretion pathway protein J"
			},
			{
				"name":"ACIAD2354 xcpX; general secretion pathway protein K\tK02460 gspK; general secretion pathway protein K"
			},
			{
				"name":"ACIAD1319 putative general secretion pathway protein L (GspL family)\tK02461 gspL; general secretion pathway protein L"
			},
			{
				"name":"ACIAD0292 putative general secretion pathway protein\tK02463 gspN; general secretion pathway protein N"
			},
			{
				"name":"ACIAD0360 pilD; type 4 prepilin-like proteins leader peptide processing enzyme (Protein secretion protein XCPA)[Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase ]\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			}
			]
		},
		{
			"name":"Pilin secretion\/fimbrial assembly protein",
			"children":[
			{
				"name":"ACIAD3338 comP; competence factor involved in DNA binding and uptake\tK02650 pilA; type IV pilus assembly protein PilA"
			},
			{
				"name":"ACIAD0362 pilB; type 4 fimbrial biogenesis protein\tK02652 pilB; type IV pilus assembly protein PilB"
			},
			{
				"name":"ACIAD0361 pilC; type 4 fimbrial assembly protein\tK02653 pilC; type IV pilus assembly protein PilC"
			},
			{
				"name":"ACIAD0360 pilD; type 4 prepilin-like proteins leader peptide processing enzyme (Protein secretion protein XCPA)[Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase ]\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"ACIAD3314 comF; pilin like competence factor\tK02655 pilE; type IV pilus assembly protein PilE"
			},
			{
				"name":"ACIAD3315 comE; pilin like competence factor\tK02655 pilE; type IV pilus assembly protein PilE"
			},
			{
				"name":"ACIAD0558 pilF; type 4 fimbrial biogenesis protein\tK02656 pilF; type IV pilus assembly protein PilF"
			},
			{
				"name":"ACIAD0786 pilG; twitching motility protein\tK02657 pilG; twitching motility two-component system response regulator PilG"
			},
			{
				"name":"ACIAD0787 pilH; twitching motility protein\tK02658 pilH; twitching motility two-component system response regulator PilH"
			},
			{
				"name":"ACIAD0788 pilI; twitching motility protein\tK02659 pilI; twitching motility protein PilI"
			},
			{
				"name":"ACIAD0789 pilJ; type IV pilus biogenesis protein\tK02660 pilJ; twitching motility protein PilJ"
			},
			{
				"name":"ACIAD3360 putative membrane protein (ComM)\tK02662 pilM; type IV pilus assembly protein PilM"
			},
			{
				"name":"ACIAD3359 putative membrane protein (ComN)\tK02663 pilN; type IV pilus assembly protein PilN"
			},
			{
				"name":"ACIAD3357 putative membrane protein (ComO)\tK02664 pilO; type IV pilus assembly protein PilO"
			},
			{
				"name":"ACIAD3356 putative lipoprotein (ComL)\tK02665 pilP; type IV pilus assembly protein PilP"
			},
			{
				"name":"ACIAD3355 putative outer membrane protein (ComQ)\tK02666 pilQ; type IV pilus assembly protein PilQ"
			},
			{
				"name":"ACIAD0912 pilT; twitching motility protein\tK02669 pilT; twitching motility protein PilT"
			},
			{
				"name":"ACIAD0911 pilU; twitching motility protein\tK02670 pilU; twitching motility protein PilU"
			},
			{
				"name":"ACIAD3319 putative type 4 fimbrial biogenesis protein (PilV)\tK02671 pilV; type IV pilus assembly protein PilV"
			},
			{
				"name":"ACIAD3318 comB; pilin like competence factor\tK02672 pilW; type IV pilus assembly protein PilW"
			},
			{
				"name":"ACIAD3317 putative type 4 fimbrial biogenesis protein (PilX)\tK02673 pilX; type IV pilus assembly protein PilX"
			},
			{
				"name":"ACIAD3316 comC; competence factor involved in DNA binding and uptake\tK02674 pilY1; type IV pilus assembly protein PilY1"
			},
			{
				"name":"ACIAD2360 pilZ; type 4 fimbrial biogenesis protein\tK02676 pilZ; type IV pilus assembly protein PilZ"
			},
			{
				"name":"ACIAD0695 putative type 4 fimbrial biogenesis protein FimT\tK08084 fimT; type IV fimbrial biogenesis protein FimT"
			},
			{
				"name":"ACIAD3321 putative type 4 fimbrial biogenesis protein (FimU)\tK08084 fimT; type IV fimbrial biogenesis protein FimT"
			}
			]
		},
		{
			"name":"Tight adherence (Tad) export apparatus"
		},
		{
			"name":"Toxin co-regulated pilus biosynthesis protein"
		},
		{
			"name":"MSHA pilus biogenesis protein"
		},
		{
			"name":"Type IVa pilus homolog protein",
			"children":[
			{
				"name":"ACIAD0360 pilD; type 4 prepilin-like proteins leader peptide processing enzyme (Protein secretion protein XCPA)[Includes: Leader peptidase (Prepilin peptidase); N-methyltransferase ]\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"ACIAD0912 pilT; twitching motility protein\tK02669 pilT; twitching motility protein PilT"
			},
			{
				"name":"ACIAD3031 conserved hypothetical protein; putative integral membrane resistance protein\tK02221 yggT; YggT family protein"
			}
			]
		},
		{
			"name":"Archaeal flagellar protein"
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) core components",
			"children":[
			{
				"name":"ACIAD3064 putative DNA uptake protein and\/or related DNA-binding protein\tK02237 comEA; competence protein ComEA"
			},
			{
				"name":"ACIAD2639 comA; competence factor involved in DNA uptake\tK02238 comEC; competence protein ComEC"
			}
			]
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) related proteins"
		}
		]
	},
	{
		"name":"Type III secretion system",
		"children":[
		{
			"name":"Type III secretion core apparatus"
		},
		{
			"name":"Type III secretion related proteins"
		},
		{
			"name":"Flagellar export apparatus"
		}
		]
	},
	{
		"name":"Type IV secretion system",
		"children":[
		{
			"name":"Conjugal DNA-protein transfer (VirB\/D) protein"
		},
		{
			"name":"DNA uptake competence system protein"
		},
		{
			"name":"Conjugal transfer pilus assembly protein",
			"children":[
			{
				"name":"ACIAD0265 dsbC; thiol:disulfide interchange protein\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"ACIAD0713 putative thiol:disulphide interchange protein (DsbC-like)\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"ACIAD3673 putative thiol:disulfide interchange protein\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			}
			]
		},
		{
			"name":"Pertussis toxin exporter"
		},
		{
			"name":"Cag pathogenicity island (PAI) protein"
		},
		{
			"name":"Icm\/Dot secretion system protein"
		},
		{
			"name":"Trb secretion system protein"
		}
		]
	},
	{
		"name":"Type V secretion system",
		"children":[
		{
			"name":"Autotransporter-1 (AT-1) family"
		},
		{
			"name":"Autotransporter-2 (AT-2) family"
		},
		{
			"name":"Two-partner secretion (TPS) family"
		}
		]
	},
	{
		"name":"Type VI secretion system",
		"children":[
		{
			"name":"Imp\/Vas secretion system core components",
			"children":[
			{
				"name":"ACIAD2684 conserved hypothetical protein; putative membrane protein\tK11891 impL; type VI secretion system protein ImpL"
			},
			{
				"name":"ACIAD2697 conserved hypothetical protein\tK11892 impK; type VI secretion system protein ImpK"
			},
			{
				"name":"ACIAD2696 conserved hypothetical protein\tK11893 impJ; type VI secretion system protein ImpJ"
			},
			{
				"name":"ACIAD2686 conserved hypothetical protein; putative secretion system (EvpG)\tK11895 impH; type VI secretion system protein ImpH"
			},
			{
				"name":"ACIAD2687 conserved hypothetical protein; putative secretion system (EvpF)\tK11896 impG; type VI secretion system protein ImpG"
			},
			{
				"name":"ACIAD2688 conserved hypothetical protein; putative secretion system (EvpE)\tK11897 impF; type VI secretion system protein ImpF"
			},
			{
				"name":"ACIAD2690 conserved hypothetical protein; putative secretion system (EvpB)\tK11900 impC; type VI secretion system protein ImpC"
			},
			{
				"name":"ACIAD2691 conserved hypothetical protein; putative secretion system (EvpA)\tK11901 impB; type VI secretion system protein ImpB"
			},
			{
				"name":"ACIAD2695 conserved hypothetical protein\tK11902 impA; type VI secretion system protein ImpA"
			},
			{
				"name":"ACIAD2689 conserved hypothetical protein; putative secretion system (EvpC)\tK11903 hcp; type VI secretion system secreted protein Hcp"
			},
			{
				"name":"ACIAD1788 conserved hypothetical protein; putative VGR-related protein\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"ACIAD3115 conserved hypothetical protein; putative VGR-related protein\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"ACIAD3427 conserved hypothetical protein; putative VGR-related protein\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"ACIAD2694 putative ClpA\/B-type chaperone\tK11907 vasG; type VI secretion system protein VasG"
			}
			]
		},
		{
			"name":"Imp\/Vas secretion system related proteins",
			"children":[
			{
				"name":"ACIAD2683 conserved hypothetical protein\tK11890 impM; type VI secretion system protein ImpM"
			}
			]
		}
		]
	},
	{
		"name":"Type VII secretion system",
		"children":[
		{
			"name":"ESX secretion system protein"
		}
		]
	},
	{
		"name":"Chaperone-usher system",
		"children":[
		{
			"name":"Type 1 pilus assembly protein",
			"children":[
			{
				"name":"ACIAD0119 putative major fimbrial subunit protein precursor\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"ACIAD0387 protein AcuA; putative fimbrial-like protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"ACIAD3335 putative pili assembly chaperone\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"ACIAD0121 putative outer membrane usher protein (probable fimbrial usher protein)\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"ACIAD0389 protein AcuC; putative fimbrial usher protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"ACIAD3334 conserved hypothetical protein; putative porin protein involved in fimbrial biogenesis (PapC-like)\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"ACIAD3332 conserved hypothetical protein\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			},
			{
				"name":"ACIAD3333 conserved hypothetical protein; putative lipoprotein signal peptide\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			},
			{
				"name":"ACIAD3336 conserved hypothetical protein; putative protein U\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			}
			]
		},
		{
			"name":"P pilus assembly protein"
		},
		{
			"name":"Mat\/Ecp fimbriae assembly protein"
		}
		]
	},
	{
		"name":"Extracellular nucleation-precipitation pathway",
		"children":[
		{
			"name":"Curli assembly protein"
		}
		]
	},
	{
		"name":"Sec (secretion) system",
		"children":[
		{
			"name":"Prokaryotic Sec-SRP core components",
			"children":[
			{
				"name":"ACIAD0648 secA; preprotein translocase, secretion protein of IISP family\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
			},
			{
				"name":"ACIAD3122 secB; molecular chaperone in protein export\tK03071 secB; preprotein translocase subunit SecB"
			},
			{
				"name":"ACIAD0588 secD; preprotein translocase, IISP family, part of the channel\tK03072 secD; preprotein translocase subunit SecD"
			},
			{
				"name":"ACIAD0300 secE; preprotein translocase IISP family, membrane subunit\tK03073 secE; preprotein translocase subunit SecE"
			},
			{
				"name":"ACIAD0587 secF; preprotein translocase, IISP family, membrane subunit\tK03074 secF; preprotein translocase subunit SecF"
			},
			{
				"name":"ACIAD0364 secG; preprotein translocase IISP family, auxillary membrane component\tK03075 secG; preprotein translocase subunit SecG"
			},
			{
				"name":"ACIAD3199 secY; secretion protein\tK03076 secY; preprotein translocase subunit SecY"
			},
			{
				"name":"ACIAD0839 ffh; 4.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			},
			{
				"name":"ACIAD2296 ftsY; cell division protein\tK03110 ftsY; fused signal recognition particle receptor"
			},
			{
				"name":"ACIAD0589 putative SecYEG protein translocase auxillary subunit (YajC)\tK03210 yajC; preprotein translocase subunit YajC"
			},
			{
				"name":"ACIAD3681 oxaA; Inner membrane protein (IMP) integration factor; binds TM regions of nascent IMPs; required for Sec-independent IMP integration; associated with the Sec translocase\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
			}
			]
		},
		{
			"name":"Prokaryotic Sec-SRP related proteins"
		},
		{
			"name":"Eukaryotic Sec-SRP protein",
			"children":[
			{
				"name":"ACIAD0839 ffh; 4.5S-RNP protein, GTP binding export factor, part of signal recognition particle with 4.5 RNA\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			}
			]
		}
		]
	},
	{
		"name":"Twin-arginine translocation (Tat) system",
		"children":[
		{
			"name":"Twin-arginine translocation (Tat) pathway protein",
			"children":[
			{
				"name":"ACIAD0523 tatA; Sec-independent protein translocase protein\tK03116 tatA; sec-independent protein translocase protein TatA"
			},
			{
				"name":"ACIAD1522 tatA; Sec-independent protein secretion pathway, translocase protein\tK03116 tatA; sec-independent protein translocase protein TatA"
			},
			{
				"name":"ACIAD0522 tatB; Sec-independent protein translocase protein\tK03117 tatB; sec-independent protein translocase protein TatB"
			},
			{
				"name":"ACIAD1521 tatB; Sec-independent protein secretion pathway, component B\tK03117 tatB; sec-independent protein translocase protein TatB"
			},
			{
				"name":"ACIAD0521 tatC; Sec-independent protein translocase protein\tK03118 tatC; sec-independent protein translocase protein TatC"
			},
			{
				"name":"ACIAD1520 tatC; Sec-independent protein secretion pathway, component C.\tK03118 tatC; sec-independent protein translocase protein TatC"
			}
			]
		}
		]
	}
	]
}
