{
	"name":"acra03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"BSY15_2607 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases",
				"children":[
				{
					"name":"BSY15_1253 lipopolysaccharide kinase family protein\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"BSY15_2531 exonuclease family protein\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"BSY15_2608 era; GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"BSY15_686 cgtA; Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"BSY15_1013 prokaryotic dksA\/traR C4-type zinc finger family protein\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"BSY15_2141 dksA; RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"BSY15_3993 nusA; transcription termination factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"BSY15_234 nusB; transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"BSY15_1811 nusG; transcription termination\/antitermination factor NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"BSY15_2835 pseudouridine synthase family protein\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"BSY15_1368 rsmA; ribosomal RNA small subunit methyltransferase A\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"BSY15_1819 rsmB; 16S rRNA (cytosine(967)-C(5))-methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"BSY15_2505 ubiE\/COQ5 methyltransferase family protein\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"BSY15_2375 rsmD; 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"BSY15_1372 RNA methyltransferase, RsmE family protein\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"BSY15_1523 rsmG; 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"BSY15_2146 rsmH; 16S rRNA (cytosine(1402)-N(4))-methyltransferase\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"BSY15_1825 rsmI; 16S rRNA (cytidine(1402)-2'-O)-methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"BSY15_2590 tetrapyrrole (Corrin\/Porphyrin) Methylases family protein\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"BSY15_840 S4 domain protein\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"BSY15_3690 RNA 2'-O ribose methyltransferase substrate binding family protein\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"BSY15_2905 ftsJ-like methyltransferase family protein\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"BSY15_3357 putative SPOUT methyltransferase family protein\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"BSY15_2138 S-adenosylmethionine-dependent methyltransferase family protein\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"BSY15_3631 methyltransferase small domain protein\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"BSY15_837 ribosomal RNA small subunit methyltransferase D, RsmJ family protein\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"BSY15_1110 THUMP domain protein\tK25137 rlmL; 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.173]"
				},
				{
					"name":"BSY15_2814 rlmN; 23S rRNA (adenine(2503)-C(2))-methyltransferase\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"BSY15_840 S4 domain protein\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"BSY15_3975 rumA; 23S rRNA (uracil-5-)-methyltransferase RumA\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"BSY15_3134 RNA pseudouridylate synthase family protein\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"BSY15_3866 RNA pseudouridylate synthase family protein\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"BSY15_2812 pseudouridine synthase family protein\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"BSY15_2586 pseudouridine synthase, RluA family protein\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"BSY15_2810 pseudouridine synthase, RluA family protein\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"BSY15_204 pseudouridine synthase family protein\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"BSY15_1935 pseudouridine synthase family protein\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				},
				{
					"name":"BSY15_2129 S4 domain protein\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"BSY15_1172 rimI; ribosomal-protein-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"BSY15_2523 rimM; 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"BSY15_4121 rimO; ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"BSY15_2266 prmA; ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"BSY15_3420 prmB; (glutamine-N5) methyltransferase, ribosomal protein L3-specific\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"BSY15_2755 araC-like ligand binding domain protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"BSY15_2607 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"BSY15_2585 ribonuclease, Rne\/Rng family domain protein\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"BSY15_3359 ribonuclease, Rne\/Rng family domain protein\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"BSY15_2311 hypothetical protein\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"BSY15_1963 DEAD\/DEAH box helicase family protein\tK05591 dbpA; ATP-dependent RNA helicase DbpA [EC:5.6.2.6]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"BSY15_2608 era; GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"BSY15_2528 rsgA; ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"BSY15_2821 engA; ribosome-associated GTPase EngA\tK03977 engA; GTPase"
			},
			{
				"name":"BSY15_686 cgtA; Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"BSY15_219 ylqF; ribosome biogenesis GTP-binding protein YlqF\tK14540 rbgA; ribosome biogenesis GTPase A"
			},
			{
				"name":"BSY15_2823 hflX; GTP-binding protein HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"BSY15_1165 tRNA threonylcarbamoyl adenosine modification protein, Sua5\/YciO\/YrdC\/YwlC family\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"BSY15_616 RelA\/SpoT family protein\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"BSY15_3991 rbfA; ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"BSY15_3994 hypothetical protein\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"BSY15_3356 rsfS; ribosome silencing factor\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"BSY15_1972 putative rRNA maturation factor YbeY\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"BSY15_2904 CRS1 \/ YhbY domain protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"BSY15_333 hypothetical protein\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"BSY15_1158 raiA; ribosomal subunit interface protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"BSY15_2291 50S ribosome-binding GTPase family protein\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"BSY15_2592 hypothetical protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}