{
	"name":"actq03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"OG417_12160 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"OG417_29635 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"OG417_37590 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"OG417_08415 DNA photolyase family protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"OG417_17690 ung; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"OG417_27130 DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"OG417_49795 DUF4279 domain-containing protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"OG417_00785 nth; endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex"
					},
					{
						"name":"DNA polymerase epsilon complex"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex"
					},
					{
						"name":"Cul4-DDB2 complex"
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex"
					},
					{
						"name":"Cul4-CSA complex"
					},
					{
						"name":"Other TCR factor"
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"OG417_46250 DEAD\/DEAH box helicase\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Other NER factors"
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"MutL homologs"
				},
				{
					"name":"DNA polymerase delta complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex"
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex"
				},
				{
					"name":"BRCA complex"
				},
				{
					"name":"RecA family proteins"
				},
				{
					"name":"Rad52 family proteins"
				},
				{
					"name":"Rad54 family proteins"
				},
				{
					"name":"RecQ family DNA helicases"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Protein phosphatase 4"
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex"
				},
				{
					"name":"Other HR factors"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex"
				},
				{
					"name":"MRX complex"
				},
				{
					"name":"DNA Ligase 4 complex"
				},
				{
					"name":"X-family DNA polymerases"
				},
				{
					"name":"Other NHEJ factors"
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors"
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others"
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"B-family DNA polymerases"
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group"
			},
			{
				"name":"Other TLS factors"
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex"
			},
			{
				"name":"HRAD17(Rad24)-RFC complex"
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex"
			},
			{
				"name":"FPC (fork protection complex)"
			},
			{
				"name":"Triple T complex"
			},
			{
				"name":"BAG6-UBL4A-GET4 complex"
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases"
			},
			{
				"name":"Nucleases"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"PSO4 complex"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"OG417_07670 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_14175 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_15935 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_23420 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_43260 (deoxy)nucleoside triphosphate pyrophosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_50005 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_39045 dut; dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"OG417_12160 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"OG417_29635 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"OG417_37590 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"OG417_08415 DNA photolyase family protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				},
				{
					"name":"OG417_41100 cryptochrome\/photolyase family protein\tK06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]"
				},
				{
					"name":"OG417_29830 alpha-ketoglutarate-dependent dioxygenase AlkB\tK03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"OG417_17690 ung; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"OG417_38715 mug; G\/U mismatch-specific DNA glycosylase\tK03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]"
					},
					{
						"name":"OG417_43795 uracil-DNA glycosylase\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"OG417_46085 UdgX family uracil-DNA binding protein\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"OG417_15365 hypothetical protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"OG417_29640 helix-turn-helix domain-containing protein\tK13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response \/ DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"OG417_38535 helix-turn-helix domain-containing protein\tK13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response \/ DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"OG417_27130 DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"OG417_49795 DUF4279 domain-containing protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"OG417_42600 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"OG417_02570 Fpg\/Nei family DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"OG417_16835 mutM; bifunctional DNA-formamidopyrimidine glycosylase\/DNA-(apurinic or apyrimidinic site) lyase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"OG417_49155 hypothetical protein\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"OG417_17785 DNA glycosylase\tK05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"OG417_00785 nth; endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"OG417_01750 deoxyribonuclease IV\tK01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]"
					},
					{
						"name":"OG417_19700 deoxyribonuclease IV\tK01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]"
					},
					{
						"name":"OG417_17395 endonuclease V\tK05982 nfi; deoxyribonuclease V [EC:3.1.21.7]"
					}
					]
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"OG417_16175 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"OG417_40635 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"OG417_20985 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"OG417_27290 uvrA; excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
					},
					{
						"name":"OG417_21020 uvrB; excinuclease ABC subunit UvrB\tK03702 uvrB; excinuclease ABC subunit B"
					},
					{
						"name":"OG417_27305 uvrC; excinuclease ABC subunit UvrC\tK03703 uvrC; excinuclease ABC subunit C"
					},
					{
						"name":"OG417_06120 pcrA; DNA helicase PcrA\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_24975 UvrD-helicase domain-containing protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_42175 ATP-dependent DNA helicase UvrD2\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_42365 ATP-dependent helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_20985 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"OG417_16175 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"OG417_40635 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"OG417_05430 rpoB; DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"OG417_05435 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"OG417_05625 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						},
						{
							"name":"OG417_19855 rpoZ; DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)",
						"children":[
						{
							"name":"OG417_43860 mfd; transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases",
					"children":[
					{
						"name":"OG417_43340 xseA; exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
					},
					{
						"name":"OG417_43350 exodeoxyribonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
					}
					]
				},
				{
					"name":"DNA polymerase III holoenzyme",
					"children":[
					{
						"name":"OG417_20625 dnaE; DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"OG417_48630 dnaE; DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"OG417_01945 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"OG417_18150 holA; DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
					},
					{
						"name":"OG417_50370 DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
					},
					{
						"name":"OG417_07905 3'-5' exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"OG417_19540 DEDD exonuclease domain-containing protein\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"OG417_46505 exonuclease domain-containing protein\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"OG417_01260 DNA polymerase III subunit gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"OG417_16175 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"OG417_40635 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"OG417_06120 pcrA; DNA helicase PcrA\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_24975 UvrD-helicase domain-containing protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_42175 ATP-dependent DNA helicase UvrD2\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_42365 ATP-dependent helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"OG417_01730 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"OG417_14330 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"OG417_27165 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"OG417_00260 very short patch repair endonuclease\tK07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"OG417_46130 ATP-dependent RecD-like DNA helicase\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"OG417_17885 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"OG417_26900 ruvA; Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"OG417_26905 ruvB; Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"OG417_26895 ruvC; crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					},
					{
						"name":"OG417_19880 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
					},
					{
						"name":"OG417_36905 SMC family ATPase\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"OG417_36910 exonuclease SbcCD subunit D\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					},
					{
						"name":"OG417_45365 exonuclease SbcCD subunit D\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"OG417_17885 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"OG417_49785 radA; DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"OG417_01955 recF; DNA replication\/repair protein RecF\tK03629 recF; DNA replication and repair protein RecF"
					},
					{
						"name":"OG417_16790 recG; ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					},
					{
						"name":"OG417_01250 recR; recombination mediator RecR\tK06187 recR; recombination protein RecR"
					},
					{
						"name":"OG417_27210 recN; DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
					},
					{
						"name":"OG417_26900 ruvA; Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"OG417_26905 ruvB; Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"OG417_26895 ruvC; crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins",
					"children":[
					{
						"name":"OG417_36905 SMC family ATPase\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"OG417_36910 exonuclease SbcCD subunit D\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					},
					{
						"name":"OG417_45365 exonuclease SbcCD subunit D\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex",
					"children":[
					{
						"name":"OG417_24755 Ku protein\tK10979 ku; DNA end-binding protein Ku"
					},
					{
						"name":"OG417_42415 Ku protein\tK10979 ku; DNA end-binding protein Ku"
					},
					{
						"name":"OG417_24730 ligD; non-homologous end-joining DNA ligase\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
					},
					{
						"name":"OG417_30385 ligD; non-homologous end-joining DNA ligase\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
					},
					{
						"name":"OG417_35050 ligD; non-homologous end-joining DNA ligase\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
					},
					{
						"name":"OG417_42420 ligD; non-homologous end-joining DNA ligase\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
					},
					{
						"name":"OG417_42425 ligD; non-homologous end-joining DNA ligase\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"OG417_01970 gyrA; DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"OG417_40855 DNA topoisomerase IV subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"OG417_01965 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"OG417_40885 type IIA DNA topoisomerase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"OG417_11705 DNA topoisomerase IB\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						},
						{
							"name":"OG417_50380 topA; type I DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						}
						]
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"OG417_16625 HU family DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
						}
						]
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway",
						"children":[
						{
							"name":"OG417_01250 recR; recombination mediator RecR\tK06187 recR; recombination protein RecR"
						},
						{
							"name":"OG417_16175 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						},
						{
							"name":"OG417_40635 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						}
						]
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"OG417_40835 RecQ family ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"OG417_41620 recQ; DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"OG417_52550 RecQ family ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"OG417_53635 ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"OG417_27290 uvrA; excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
						},
						{
							"name":"OG417_21020 uvrB; excinuclease ABC subunit UvrB\tK03702 uvrB; excinuclease ABC subunit B"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"OG417_11255 DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"OG417_20370 DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"OG417_17885 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"OG417_41245 lexA; transcriptional repressor LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"OG417_27210 recN; DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"OG417_21905 DNA polymerase Y family protein\tK14161 imuB; protein ImuB"
				},
				{
					"name":"OG417_21900 error-prone DNA polymerase\tK14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]"
				},
				{
					"name":"OG417_01730 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"OG417_14330 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"OG417_27165 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"OG417_17890 recombination regulator RecX\tK03565 recX; regulatory protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase",
				"children":[
				{
					"name":"OG417_27480 polX; DNA polymerase\/3'-5' exonuclease PolX\tK02347 polX; DNA polymerase (family X)"
				}
				]
			},
			{
				"name":"DNA helicases",
				"children":[
				{
					"name":"OG417_41310 ATP-dependent DNA helicase\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"OG417_17850 ATP-dependent helicase\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				},
				{
					"name":"OG417_22755 DEAD\/DEAH box helicase\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"OG417_07670 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_14175 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_15935 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_23420 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_43260 (deoxy)nucleoside triphosphate pyrophosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_50005 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"OG417_06705 NUDIX hydrolase\tK23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]"
				},
				{
					"name":"OG417_21080 NUDIX hydrolase\tK01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"OG417_39045 dut; dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"OG417_25485 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"OG417_41230 vitamin B12-dependent ribonucleotide reductase\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"OG417_51950 ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"OG417_51945 ribonucleotide-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"OG417_17575 bifunctional oligoribonuclease\/PAP phosphatase NrnA\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				}
				]
			}
			]
		}
		]
	}
	]
}