{
	"name":"adl03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"AURDEDRAFT_63409 guanine-N(7)-methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"AURDEDRAFT_59909 CMGC\/CDK\/CDC2 protein kinase\tK04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22]"
					},
					{
						"name":"AURDEDRAFT_85223 Pkinase-domain-containing protein\tK04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22]"
					},
					{
						"name":"AURDEDRAFT_183660 Pkinase-domain-containing protein\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"AURDEDRAFT_86228 Pkinase-domain-containing protein\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"AURDEDRAFT_145190 mRNA capping enzyme, alpha subunit\tK00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]"
					},
					{
						"name":"AURDEDRAFT_111235 mRNA triphosphatase CET1\tK01098 CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74]"
					},
					{
						"name":"AURDEDRAFT_112500 mRNA triphosphatase CET1\tK01098 CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74]"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"AURDEDRAFT_180466 hypothetical protein\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"AURDEDRAFT_110801 RNA-binding domain-containing protein\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"AURDEDRAFT_172593 cleavage and polyadenylation specific factor 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"AURDEDRAFT_97463 cleavage\/polyadenylation factor ia subunit Clp1p\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"AURDEDRAFT_110499 hypothetical protein\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"AURDEDRAFT_81080 hypothetical protein\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"AURDEDRAFT_183466 hypothetical protein\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"AURDEDRAFT_142545 Metallo-hydrolase\/oxidoreductase\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"AURDEDRAFT_78116 hypothetical protein\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"AURDEDRAFT_155044 hypothetical protein\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"AURDEDRAFT_61621 DWNN-domain-containing protein\tK15541 MPE1; protein MPE1"
					},
					{
						"name":"AURDEDRAFT_68095 DWNN-domain-containing protein\tK15541 MPE1; protein MPE1"
					},
					{
						"name":"AURDEDRAFT_74901 DWNN-domain-containing protein\tK15541 MPE1; protein MPE1"
					},
					{
						"name":"AURDEDRAFT_87442 WD40 repeat-like protein\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"AURDEDRAFT_112483 WD40 repeat-like protein\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"AURDEDRAFT_111885 serine\/threonine-protein phosphatase PP1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"AURDEDRAFT_111889 protein phosphatase type 1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"AURDEDRAFT_114234 putative serine\/threonine protein phosphatase PP1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"AURDEDRAFT_94160 phospho protein phosphatase PPZ\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"AURDEDRAFT_110555 Ssu72-domain-containing protein\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"AURDEDRAFT_142864 hypothetical protein\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"AURDEDRAFT_152877 Suf-domain-containing protein\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"AURDEDRAFT_93458 Suf-domain-containing protein\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"AURDEDRAFT_65903 hypothetical protein\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"AURDEDRAFT_83800 Sm-like ribonucleo protein\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"AURDEDRAFT_111082 Sm-like ribonucleo protein\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"AURDEDRAFT_50301 hypothetical protein\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"AURDEDRAFT_133517 mRNA processing-related protein\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"AURDEDRAFT_52977 LSM-domain-containing protein\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"AURDEDRAFT_183466 hypothetical protein\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"AURDEDRAFT_142545 Metallo-hydrolase\/oxidoreductase\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"AURDEDRAFT_142864 hypothetical protein\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"AURDEDRAFT_65903 hypothetical protein\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"AURDEDRAFT_52254 transcription initiation protein spt4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"AURDEDRAFT_115442 transcription elongation factor Spt5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"AURDEDRAFT_96559 MT-A70-domain-containing protein\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]"
					},
					{
						"name":"AURDEDRAFT_98965 MT-A70-domain-containing protein\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"AURDEDRAFT_176350 hypothetical protein\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"AURDEDRAFT_127329 hypothetical protein\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"AURDEDRAFT_170002 hypothetical protein\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"AURDEDRAFT_110465 polymerase\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"AURDEDRAFT_109804 hypothetical protein\tK13192 RBM26; RNA-binding protein 26"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"AURDEDRAFT_100011 zinc finger protein RTS2\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"AURDEDRAFT_110707 hypothetical protein\tK27103 SRRT; serrate RNA effector molecule"
				},
				{
					"name":"AURDEDRAFT_115882 hypothetical protein\tK23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"AURDEDRAFT_114514 Y14 protein\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"AURDEDRAFT_187812 hypothetical protein\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"AURDEDRAFT_111799 hypothetical protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"AURDEDRAFT_116082 hypothetical protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"AURDEDRAFT_143112 RNA-binding domain-containing protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"AURDEDRAFT_109646 P-loop containing nucleoside triphosphate hydrolase protein\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_110391 ATP-dependent RNA helicase FAL1\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_161231 hypothetical protein\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"AURDEDRAFT_117400 hypothetical protein\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"AURDEDRAFT_64538 PWI domain-containing protein\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"AURDEDRAFT_156143 hypothetical protein\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"AURDEDRAFT_148711 hypothetical protein\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"AURDEDRAFT_180352 WD40 repeat-like protein\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"AURDEDRAFT_111799 hypothetical protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"AURDEDRAFT_116082 hypothetical protein\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"AURDEDRAFT_143112 RNA-binding domain-containing protein\tK12881 THOC4; THO complex subunit 4"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"AURDEDRAFT_175463 hypothetical protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"AURDEDRAFT_160431 hypothetical protein\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"AURDEDRAFT_95241 Ca2+-binding EF-hand superfamily protein\tK16466 CETN3; centrin-3"
					},
					{
						"name":"AURDEDRAFT_115702 hypothetical protein\tK23719 SAC3; nuclear mRNA export protein SAC3"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"AURDEDRAFT_112653 WD40 repeat-like protein\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"AURDEDRAFT_112895 polyA+ RNA export\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"AURDEDRAFT_115695 WD40 repeat-like protein\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"AURDEDRAFT_113184 hypothetical protein\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"AURDEDRAFT_160791 hypothetical protein\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"AURDEDRAFT_55921 hypothetical protein\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"AURDEDRAFT_110380 hypothetical protein\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"AURDEDRAFT_141174 nucleoporin-interacting protein NIC96\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"AURDEDRAFT_149853 hypothetical protein\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"AURDEDRAFT_161152 hypothetical protein\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"AURDEDRAFT_110780 hypothetical protein\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"AURDEDRAFT_154894 hypothetical protein\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"AURDEDRAFT_50677 nucleoporin-domain-containing protein\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"AURDEDRAFT_113210 hypothetical protein\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"AURDEDRAFT_184350 hypothetical protein\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"AURDEDRAFT_186764 hypothetical protein\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"AURDEDRAFT_153848 WD40 repeat-like protein\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"AURDEDRAFT_84084 WD40 repeat-like protein\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"AURDEDRAFT_114834 hypothetical protein\tK18716 NUP42; nucleoporin NUP42"
					},
					{
						"name":"AURDEDRAFT_80006 hypothetical protein\tK18719 NUP82; nucleoporin NUP82"
					},
					{
						"name":"AURDEDRAFT_82197 hypothetical protein\tK18722 NUP2; nucleoporin NUP2"
					},
					{
						"name":"AURDEDRAFT_95241 Ca2+-binding EF-hand superfamily protein\tK16466 CETN3; centrin-3"
					},
					{
						"name":"AURDEDRAFT_111191 hypothetical protein\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"AURDEDRAFT_92212 NTF2-like protein\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"AURDEDRAFT_132944 NTF2-like protein\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					},
					{
						"name":"AURDEDRAFT_94875 hypothetical protein\tK18725 POM152; nucleoporin POM152"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"AURDEDRAFT_115136 GTP-binding nuclear protein\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"AURDEDRAFT_108989 hypothetical protein\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"AURDEDRAFT_113294 AAA ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"AURDEDRAFT_59449 hypothetical protein\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]"
					},
					{
						"name":"AURDEDRAFT_113759 hypothetical protein\tK14290 XPO1; exportin-1"
					},
					{
						"name":"AURDEDRAFT_145424 hypothetical protein\tK14290 XPO1; exportin-1"
					},
					{
						"name":"AURDEDRAFT_74631 RNI-like protein\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"AURDEDRAFT_82921 Ran GTPase activator\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"AURDEDRAFT_63716 nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"AURDEDRAFT_109756 eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"AURDEDRAFT_114760 translation initiation factor eIF4e\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"AURDEDRAFT_65943 translation initiation factor eIF4e\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"AURDEDRAFT_110926 DEAD-domain-containing protein\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"AURDEDRAFT_53490 P-loop containing nucleoside triphosphate hydrolase protein\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"AURDEDRAFT_115891 hypothetical protein\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"AURDEDRAFT_112442 hypothetical protein\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"AURDEDRAFT_114526 DEAD-domain-containing protein\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_109635 hypothetical protein\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"AURDEDRAFT_110776 polyadenylate binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"AURDEDRAFT_58748 hypothetical protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"AURDEDRAFT_64181 antiviral helicase\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"AURDEDRAFT_53386 Sec63-domain-containing protein\tK18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6]"
					},
					{
						"name":"AURDEDRAFT_136922 hypothetical protein\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"AURDEDRAFT_139613 density-regulated protein DRP1\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex"
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"AURDEDRAFT_114875 RNA-binding domain-containing protein\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"AURDEDRAFT_52733 hypothetical protein\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"AURDEDRAFT_141742 hypothetical protein\tK06965 PELO; protein pelota"
					},
					{
						"name":"AURDEDRAFT_52753 RNA-binding domain-containing protein\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"AURDEDRAFT_110650 DEAD-domain-containing protein\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_110959 protein prenylyltransferase\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"AURDEDRAFT_187883 hypothetical protein\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"AURDEDRAFT_158159 RCC1\/BLIP-II\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"AURDEDRAFT_113261 hypothetical protein\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					},
					{
						"name":"AURDEDRAFT_111792 RNA-binding domain-containing protein\tK28506 GBP2; serine\/arginine (SR)-type shuttling mRNA binding protein"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"AURDEDRAFT_101440 peptide chain release factor eRF\/aRF subunit 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"AURDEDRAFT_113790 peptide chain release factor eRF\/aRF subunit 1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"AURDEDRAFT_79954 hypothetical protein\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"AURDEDRAFT_149003 ATP dependent helicase\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"AURDEDRAFT_142584 ARM repeat-containing protein\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"AURDEDRAFT_181525 hypothetical protein\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"AURDEDRAFT_143929 serine\/threonine specific protein phosphatase Sit4\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"AURDEDRAFT_113344 Ser\/Thr protein phosphatase 2A regulatory subunit A\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"AURDEDRAFT_61442 protein phosphatase 2A regulatory subunit PR55\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"AURDEDRAFT_96864 protein phosphatase 2A regulatory B subunit\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"AURDEDRAFT_109635 hypothetical protein\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"AURDEDRAFT_111236 P-loop containing nucleoside triphosphate hydrolase protein\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"AURDEDRAFT_114151 ARM repeat-containing protein\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"AURDEDRAFT_114437 eukaryotic type KH-domain (KH-domain type I)\tK18738 HEK; heterogeneous nuclear rnp K-like protein"
					},
					{
						"name":"AURDEDRAFT_50272 hypothetical protein\tK18738 HEK; heterogeneous nuclear rnp K-like protein"
					},
					{
						"name":"AURDEDRAFT_111039 myosin 5\tK10357 MYO5; myosin V"
					},
					{
						"name":"AURDEDRAFT_112824 hypothetical protein\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					},
					{
						"name":"AURDEDRAFT_150817 hypothetical protein\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					},
					{
						"name":"AURDEDRAFT_180678 hypothetical protein\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals"
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"AURDEDRAFT_109923 translation elongation factor 1a\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"AURDEDRAFT_109924 translation elongation factor\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"AURDEDRAFT_109926 translation elongation factor 1a\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"AURDEDRAFT_114613 elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"AURDEDRAFT_52897 RNB-domain-containing protein\tK18748 SSD1; protein SSD1"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"AURDEDRAFT_110348 Piwi-domain-containing protein\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"AURDEDRAFT_110396 eukaryotic translation initiation factor 2C\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"AURDEDRAFT_164623 Piwi-domain-containing protein\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"AURDEDRAFT_164636 Piwi-domain-containing protein\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"AURDEDRAFT_167538 Piwi-domain-containing protein\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"AURDEDRAFT_180721 Piwi-domain-containing protein\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"AURDEDRAFT_185194 Piwi-domain-containing protein\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"AURDEDRAFT_109756 eukaryotic translation initiation factor 4E\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"AURDEDRAFT_114760 translation initiation factor eIF4e\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"AURDEDRAFT_65943 translation initiation factor eIF4e\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"AURDEDRAFT_149003 ATP dependent helicase\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"AURDEDRAFT_114526 DEAD-domain-containing protein\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_139245 DEAD-domain-containing protein\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_185567 P-loop containing nucleoside triphosphate hydrolase protein\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"AURDEDRAFT_79693 P-loop containing nucleoside triphosphate hydrolase protein\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"AURDEDRAFT_95460 P-loop containing nucleoside triphosphate hydrolase protein\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"AURDEDRAFT_115398 ARM repeat-containing protein\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"AURDEDRAFT_126667 ARM repeat-containing protein\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"AURDEDRAFT_187081 kinase-like protein\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"AURDEDRAFT_183925 DCP2-domain-containing protein\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"AURDEDRAFT_109668 Sm-like ribonucleo protein\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"AURDEDRAFT_165237 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"AURDEDRAFT_165238 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"AURDEDRAFT_74096 LSM-domain-containing protein\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"AURDEDRAFT_102714 Sm-like ribonucleo protein\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"AURDEDRAFT_155392 Sm-like ribonucleo protein\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"AURDEDRAFT_30625 like-Sm ribonucleo protein\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"AURDEDRAFT_117141 U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"AURDEDRAFT_91236 LSM-domain-containing protein\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"AURDEDRAFT_111039 myosin 5\tK10357 MYO5; myosin V"
					},
					{
						"name":"AURDEDRAFT_112992 tubulin alpha-1B chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"AURDEDRAFT_112996 tubulin alpha-1A chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"AURDEDRAFT_157903 Not1-domain-containing protein\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"AURDEDRAFT_54059 Not1-domain-containing protein\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"AURDEDRAFT_101086 hypothetical protein\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"AURDEDRAFT_156875 hypothetical protein\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"AURDEDRAFT_164723 hypothetical protein\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"AURDEDRAFT_111368 glucose-repressible alcohol dehydrogenase transcriptional effector\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"AURDEDRAFT_114007 CAF1-domain-containing protein\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"AURDEDRAFT_87257 hypothetical protein\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"AURDEDRAFT_115616 hypothetical protein\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"AURDEDRAFT_113112 hypothetical protein\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"AURDEDRAFT_123069 hypothetical protein\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"AURDEDRAFT_142584 ARM repeat-containing protein\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"AURDEDRAFT_181525 hypothetical protein\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"AURDEDRAFT_78882 hypothetical protein\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"AURDEDRAFT_110890 YTH-domain-containing protein\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"AURDEDRAFT_49579 RNA-binding domain-containing protein\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"AURDEDRAFT_110776 polyadenylate binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"AURDEDRAFT_58748 hypothetical protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"AURDEDRAFT_112344 NTF2-domain-containing protein\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"AURDEDRAFT_101406 translation initiation factor eIF-2A\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"AURDEDRAFT_56225 translation initiation factor eIF-3b\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"AURDEDRAFT_110926 DEAD-domain-containing protein\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"AURDEDRAFT_53490 P-loop containing nucleoside triphosphate hydrolase protein\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"AURDEDRAFT_110391 ATP-dependent RNA helicase FAL1\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_112442 hypothetical protein\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"AURDEDRAFT_115891 hypothetical protein\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"AURDEDRAFT_111201 guanine nucleotide binding protein beta subunit\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"AURDEDRAFT_92212 NTF2-like protein\tK14284 NXF; nuclear RNA export factor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"AURDEDRAFT_183925 DCP2-domain-containing protein\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"AURDEDRAFT_139245 DEAD-domain-containing protein\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"AURDEDRAFT_113112 hypothetical protein\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"AURDEDRAFT_123069 hypothetical protein\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"AURDEDRAFT_109668 Sm-like ribonucleo protein\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"AURDEDRAFT_165237 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"AURDEDRAFT_165238 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"AURDEDRAFT_74096 LSM-domain-containing protein\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"AURDEDRAFT_102714 Sm-like ribonucleo protein\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"AURDEDRAFT_155392 Sm-like ribonucleo protein\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"AURDEDRAFT_30625 like-Sm ribonucleo protein\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"AURDEDRAFT_117141 U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"AURDEDRAFT_91236 LSM-domain-containing protein\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases"
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"AURDEDRAFT_174660 mRNA decapping enzyme\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"AURDEDRAFT_88525 hypothetical protein\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"AURDEDRAFT_141912 exosome complex exonuclease RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"AURDEDRAFT_60073 exosome component 4\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"AURDEDRAFT_58674 hypothetical protein\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"AURDEDRAFT_81203 ribosomal protein S5 domain 2-like protein\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"AURDEDRAFT_132720 ribosomal protein S5 domain 2-like protein\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"AURDEDRAFT_110988 hypothetical protein\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"AURDEDRAFT_50380 ribosomal protein S5 domain 2-like protein\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"AURDEDRAFT_159928 hypothetical protein\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"AURDEDRAFT_185410 P-loop containing nucleoside triphosphate hydrolase protein\tK20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"AURDEDRAFT_110914 Nucleotidyltransferase\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"AURDEDRAFT_108144 antiviral helicase\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"AURDEDRAFT_64181 antiviral helicase\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"AURDEDRAFT_55265 TPR-like protein\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"AURDEDRAFT_132652 WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"AURDEDRAFT_111368 glucose-repressible alcohol dehydrogenase transcriptional effector\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"AURDEDRAFT_157903 Not1-domain-containing protein\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"AURDEDRAFT_54059 Not1-domain-containing protein\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"AURDEDRAFT_101086 hypothetical protein\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"AURDEDRAFT_156875 hypothetical protein\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"AURDEDRAFT_164723 hypothetical protein\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"AURDEDRAFT_114007 CAF1-domain-containing protein\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"AURDEDRAFT_162901 Rcd1-domain-containing protein\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"AURDEDRAFT_141577 P-loop containing nucleoside triphosphate hydrolase protein\tK12608 CAF16; CCR4-NOT complex subunit CAF16"
					},
					{
						"name":"AURDEDRAFT_112791 hypothetical protein\tK12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"AURDEDRAFT_87257 hypothetical protein\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"AURDEDRAFT_115616 hypothetical protein\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"AURDEDRAFT_133758 hypothetical protein\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"AURDEDRAFT_174660 mRNA decapping enzyme\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"AURDEDRAFT_78772 DUF1740-domain-containing protein\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"AURDEDRAFT_116208 hypothetical protein\tK27407 VTS1; RNA-binding protein VTS1"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"AURDEDRAFT_180084 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"AURDEDRAFT_88005 ribonuclease H-like protein\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"AURDEDRAFT_51988 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"AURDEDRAFT_112756 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"AURDEDRAFT_113448 PFK-domain-containing protein\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"AURDEDRAFT_115888 heat shock protein\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"AURDEDRAFT_112236 chaperonin GroL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"AURDEDRAFT_88525 hypothetical protein\tK03679 RRP4; exosome complex component RRP4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"AURDEDRAFT_60073 exosome component 4\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"AURDEDRAFT_132720 ribosomal protein S5 domain 2-like protein\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}