{
	"name":"aeo01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"O23A_p3287 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"O23A_p3979 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"O23A_p3234 UDP-N-acetylmuramate--alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"O23A_p3237 UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"O23A_p3240 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"O23A_p1545 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"O23A_p1072 Alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"O23A_p2649 Alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"O23A_p3555 Glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase"
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"O23A_p3238 Phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"O23A_p3235 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"O23A_p3908 Undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"O23A_p2781 Membrane-associated phospholipid phosphatase\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"O23A_p2921 putative peptidoglycan lipid-2 flippase MurJ\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"O23A_p0291 Multimodular transpeptidase-transglycosylase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"O23A_p2813 Multimodular transpeptidase-transglycosylase\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"O23A_p1865 Penicillin-insensitive transglycosylase\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"O23A_p0231 Penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"O23A_p3241 Cell division protein FtsI\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"O23A_p0227 D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"O23A_p0974 D-alanyl-D-alanine carboxypeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"O23A_p1613 Murein-DD-endopeptidase\tK07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]"
			},
			{
				"name":"O23A_p4278 Murein-DD-endopeptidase\tK07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"O23A_p1286 Monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"O23A_p3236 Cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"O23A_p0230 Rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase",
			"children":[
			{
				"name":"O23A_p0210 LysM domain protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"O23A_p0470 hypothetical protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"O23A_p4408 LysM domain protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"O23A_p0370 hypothetical protein\tK21470 ldtD; L,D-transpeptidase"
			}
			]
		},
		{
			"name":"Carboxypeptidase"
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"O23A_p1030 Penicillin-insensitive murein endopeptidase\tK07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]"
			},
			{
				"name":"O23A_p3083 Murein DD-endopeptidase MepM\tK19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Sortase"
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"O23A_p2010 Soluble lytic murein transglycosylase\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p1336 Membrane-bound lytic murein transglycosylase A\tK08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p0229 Membrane-bound lytic murein transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p1292 Membrane-bound lytic murein transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p2030 Membrane-bound lytic murein transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p3140 Membrane-bound lytic murein transglycosylase C\tK08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p2004 Membrane-bound lytic murein transglycosylase D\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p1792 Membrane-bound lytic murein transglycosylase F\tK18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p1432 YceG-like protein\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p0228 Septum-associated rare lipoprotein A\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"O23A_p1520 Rare lipoprotein A\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"O23A_p2742 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"O23A_p4469 N-acetylmuramoyl-L-alanine amidase\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"O23A_p3216 1,6-anhydro-N-acetylmuramyl-L-alanine amidase\tK03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein",
			"children":[
			{
				"name":"O23A_p0462 murein lipoprotein\tK06078 lpp; murein lipoprotein"
			}
			]
		}
		]
	}
	]
}