{
	"name":"aflr03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"100870438 mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"100866142 mRNA-capping enzyme\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]"
					},
					{
						"name":"100873003 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"100869142 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"100867313 LOW QUALITY PROTEIN: nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"100867155 nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"100871854 cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"100868245 LOW QUALITY PROTEIN: cleavage and polyadenylation specificity factor subunit CG7185\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"100870156 LOW QUALITY PROTEIN: protein CLP1 homolog\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"100865441 LOW QUALITY PROTEIN: uncharacterized protein LOC100865441\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"100870333 cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"100868545 probable cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"100867266 cleavage and polyadenylation specificity factor 73\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"100864211 cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"100864573 pre-mRNA 3'-end-processing factor FIP1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"100862976 uncharacterized protein LOC100862976\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"100863828 WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"100863600 serine\/threonine-protein phosphatase PP1-beta catalytic subunit isoform X2\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100865037 serine\/threonine-protein phosphatase alpha-2 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100873000 RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"100866837 cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"100865964 cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"100871625 protein suppressor of forked\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"100865018 symplekin isoform X2\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"105735056 small nuclear ribonucleoprotein-associated protein B\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"100868527 small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"100867517 small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"100869584 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"100872469 U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11"
					},
					{
						"name":"100868545 probable cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"100867266 cleavage and polyadenylation specificity factor 73\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"100865964 cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"100865018 symplekin isoform X2\tK06100 SYMPK; symplekin"
					},
					{
						"name":"100868498 LOW QUALITY PROTEIN: histone RNA hairpin-binding protein\tK18710 SLBP; histone RNA hairpin-binding protein"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"100871439 transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"100866067 transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"100872617 LOW QUALITY PROTEIN: N6-adenosine-methyltransferase catalytic subunit\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]"
					},
					{
						"name":"100871913 N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"100865329 N(6)-adenine-specific DNA methyltransferase METTL4\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"100865169 LOW QUALITY PROTEIN: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"100866562 pre-mRNA-splicing regulator WTAP isoform X1\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"100872984 protein virilizer\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"100870205 RNA-binding protein spenito isoform X2\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"100868884 LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 13\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"100871420 uncharacterized protein DDB_G0283697 isoform X1\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"100864501 E3 ubiquitin-protein ligase Hakai\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"100866076 poly(A) polymerase type 3 isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"100864072 poly(A) RNA polymerase gld-2 homolog A-like isoform X2\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"100864380 LOW QUALITY PROTEIN: BRCA1-associated RING domain protein 1-like\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"100869688 RNA-binding protein 26\tK13192 RBM26; RNA-binding protein 26"
					},
					{
						"name":"100866148 TAR DNA-binding protein 43 isoform X1\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"100871563 DNA\/RNA-binding protein KIN17\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"100864350 methyltransferase-like protein 22\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"100866733 terminal nucleotidyltransferase 5C isoform X2\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"100867511 zinc finger CCCH domain-containing protein 14\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"100867943 RNA-binding protein 8A\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"100871558 protein mago nashi homolog\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"100867642 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"100863123 ATP-dependent RNA helicase WM6\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"100870400 eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"100865845 coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"100865339 protein CASC3 isoform X1\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"100867544 histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"100864812 pinin\tK13114 PNN; pinin"
					},
					{
						"name":"100868000 LOW QUALITY PROTEIN: apoptotic chromatin condensation inducer in the nucleus\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus"
					},
					{
						"name":"100871217 RNA-binding protein with serine-rich domain 1\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"100871392 serine\/arginine repetitive matrix protein 1 isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"100865332 LOW QUALITY PROTEIN: THO complex subunit 1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"100863371 THO complex subunit 2 isoform X1\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"100865314 THO complex subunit 3\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"100867642 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"100872256 THO complex subunit 5 homolog isoform X1\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"100865334 THO complex subunit 6 homolog\tK13175 THOC6; THO complex subunit 6"
					},
					{
						"name":"105736772 THO complex subunit 7 homolog isoform X1\tK13176 THOC7; THO complex subunit 7"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"100865824 PCI domain-containing protein 2\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"100863585 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"100868469 transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"100872866 LOW QUALITY PROTEIN: nucleoprotein TPR\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"100867984 mRNA export factor\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"100864611 protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"100872913 nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"100869022 nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"100866582 LOW QUALITY PROTEIN: nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"100867751 nuclear pore complex protein Nup54 isoform X1\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"100864755 LOW QUALITY PROTEIN: nuclear pore glycoprotein p62\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"100867958 nuclear pore complex protein Nup93-like\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"100871975 nuclear pore complex protein Nup98-Nup96 isoform X4\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"100869765 nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"100863368 LOW QUALITY PROTEIN: nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"100870635 nucleoporin NUP188 homolog\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"100865653 LOW QUALITY PROTEIN: nuclear pore complex protein Nup153\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"100868651 nuclear pore complex protein Nup154 isoform X1\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"100863141 LOW QUALITY PROTEIN: nuclear pore complex protein Nup160 homolog\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"100864991 LOW QUALITY PROTEIN: uncharacterized protein LOC100864991\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"100868867 nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"100868465 nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"100866545 LOW QUALITY PROTEIN: nuclear pore complex protein Nup214\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"100864267 nucleoporin p58\/p45 isoform X1\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"100866930 nucleoporin NDC1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"100868931 nucleoporin SEH1 isoform X1\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"100866705 E3 SUMO-protein ligase RanBP2 isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
					},
					{
						"name":"100866759 aladin-like\tK14320 AAAS; aladin"
					},
					{
						"name":"100865062 nucleoporin NUP42 isoform X2\tK18716 NUP42; nucleoporin NUP42"
					},
					{
						"name":"100871230 nucleoporin GLE1 isoform X1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"100864078 LOW QUALITY PROTEIN: nuclear RNA export factor 1-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100864616 LOW QUALITY PROTEIN: nuclear RNA export factor 1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105737428 nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100864997 NTF2-related export protein isoform X2\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"100869865 LOW QUALITY PROTEIN: GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"100869424 acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X2\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"100863350 ELAV-like protein 3 isoform X2\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"100872683 FAS-associated factor 2\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"100872366 LOW QUALITY PROTEIN: transitional endoplasmic reticulum ATPase TER94\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"100865600 exportin-1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"100866229 LOW QUALITY PROTEIN: exportin-7\tK18460 XPO7; exportin-7"
					},
					{
						"name":"100871302 LOW QUALITY PROTEIN: ran GTPase-activating protein 1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"100871964 probable nuclear transport factor 2 isoform X1\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"100867046 eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100868466 eukaryotic translation initiation factor 4E-1A isoform X2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100870145 eukaryotic initiation factor 4A-I\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"100863761 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100871147 eukaryotic translation initiation factor 4 gamma 2 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100870171 eukaryotic translation initiation factor 4B\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"100863032 eukaryotic translation initiation factor 4H isoform X1\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"100868329 eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2"
					},
					{
						"name":"100868231 eukaryotic translation initiation factor 4E transporter isoform X4\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"100871010 LOW QUALITY PROTEIN: protein angel\tK18729 ANGEL; protein angel"
					},
					{
						"name":"100871882 synaptic functional regulator FMR1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100864838 LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"100866056 gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"100866445 cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100868293 cytoplasmic polyadenylation element-binding protein 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100869586 LOW QUALITY PROTEIN: putative ATP-dependent RNA helicase Pl10\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"116413864 LOW QUALITY PROTEIN: GRB10-interacting GYF protein 2-like\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"100872848 polyadenylate-binding protein 1 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100867607 polyadenylate-binding protein-interacting protein 1 isoform X1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"100866577 polyadenylate-binding protein-interacting protein 2 isoform X3\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"100863116 LOW QUALITY PROTEIN: helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"100864961 deformed epidermal autoregulatory factor 1\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"100865976 malignant T-cell-amplified sequence 1 homolog\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"100865410 density-regulated protein homolog isoform X1\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex"
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"100872559 partner of Y14 and mago\tK14294 WIBG; partner of Y14 and mago"
					},
					{
						"name":"100868777 heterogeneous nuclear ribonucleoprotein A1, A2\/B1 homolog isoform X2\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100863440 RNA-binding protein Musashi homolog Rbp6 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"100867561 heterogeneous nuclear ribonucleoprotein 27C isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"100871308 LOW QUALITY PROTEIN: HBS1-like protein\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"100870047 protein pelota isoform X1\tK06965 PELO; protein pelota"
					},
					{
						"name":"100872248 polyadenylate-binding protein 2-B\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"100865220 DEAD-box helicase Dbp80 isoform X1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"100869086 pre-mRNA-splicing factor syf1 homolog isoform X1\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"100867983 LOW QUALITY PROTEIN: SAP domain-containing ribonucleoprotein\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"100871740 regulator of chromosome condensation isoform X1\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"105735015 la-related protein 6\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"100872642 transcriptional activator protein Pur-beta-B isoform X2\tK21772 PURA; transcriptional activator protein Pur-alpha"
					},
					{
						"name":"100869814 uncharacterized protein LOC100869814\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"100869972 LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 11A\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"100865766 LOW QUALITY PROTEIN: leukocyte receptor cluster member 8 homolog\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"100868873 eukaryotic peptide chain release factor subunit 1 isoform X1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"100866140 LOW QUALITY PROTEIN: eukaryotic peptide chain release factor GTP-binding subunit ERF3A\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"100863606 regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"100870926 regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"100871304 LOW QUALITY PROTEIN: regulator of nonsense transcripts 3A\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"100869181 serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100868269 serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"100871826 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X2\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"100864098 uncharacterized protein LOC100864098 isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"100867941 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"100868067 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"100868012 serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"100872457 protein SMG5 isoform X1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"100866761 telomerase-binding protein EST1A-like isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"100872334 protein SMG7-like\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"100864946 protein SMG8\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"100869380 protein SMG9\tK18735 SMG9; protein SMG9"
					},
					{
						"name":"116413864 LOW QUALITY PROTEIN: GRB10-interacting GYF protein 2-like\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"100869838 LOW QUALITY PROTEIN: uncharacterized protein LOC100869838\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"100872638 LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DHX34\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]"
					},
					{
						"name":"100869371 GTP-binding protein 1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"100867261 pumilio homolog 3\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"100867468 LOW QUALITY PROTEIN: unconventional myosin-Va\tK10357 MYO5; myosin V"
					},
					{
						"name":"100868227 LOW QUALITY PROTEIN: protein bicaudal D\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"100862929 egalitarian protein homolog\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"100866369 actin, clone 403-like\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"100866921 actin-5C\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"100872737 actin, muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"100872857 actin, clone 205\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105735372 uncharacterized protein LOC105735372 isoform X1\tK04377 MYC; Myc proto-oncogene protein"
					},
					{
						"name":"100864343 T-box transcription factor TBX6-like\tK10180 TBX6; T-box protein 6"
					},
					{
						"name":"100865915 protein hairy isoform X1\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"100866385 LOW QUALITY PROTEIN: protein deadpan\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"100868384 enhancer of split mgamma protein-like\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"100869241 enhancer of split mbeta protein-like\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"100869361 enhancer of split m7 protein-like\tK09090 HESN; hairy and enhancer of split, invertebrate"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"100867879 LOW QUALITY PROTEIN: far upstream element-binding protein 3\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"100866051 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"100867741 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"100863722 elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"105735185 uncharacterized protein LOC105735185\tK16220 HAX1; HCLS1-associated protein X-1"
					},
					{
						"name":"100863391 arf-GAP domain and FG repeat-containing protein 1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"100868029 LOW QUALITY PROTEIN: double-stranded RNA-binding protein Staufen homolog 2\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"100871266 polypyrimidine tract-binding protein 2 isoform X7\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"100866147 LOW QUALITY PROTEIN: RNA-binding protein squid\tK03102 SQD; squid"
					},
					{
						"name":"100870713 RNA-binding protein squid\tK03102 SQD; squid"
					},
					{
						"name":"100866445 cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100868293 cytoplasmic polyadenylation element-binding protein 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"100871882 synaptic functional regulator FMR1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100864838 LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"100865510 poly(rC)-binding protein 4 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"100866466 caprin homolog\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"100869770 CUGBP Elav-like family member 2 isoform X10\tK02177 BRU; bruno"
					},
					{
						"name":"100870924 maternal protein exuperantia\tK18745 EXU; maternal protein exuperantia"
					},
					{
						"name":"100863011 Y-box factor homolog isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"100866303 LOW QUALITY PROTEIN: sex-lethal homolog\tK18747 SXL; protein sex-lethal"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"100872253 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"100870792 protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"105735140 protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"100867046 eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100868466 eukaryotic translation initiation factor 4E-1A isoform X2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"100863606 regulator of nonsense transcripts 1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"100869586 LOW QUALITY PROTEIN: putative ATP-dependent RNA helicase Pl10\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"100871565 ATP-dependent RNA helicase me31b\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"100869708 RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"105734816 LOW QUALITY PROTEIN: protein LSM14 homolog A\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"100863011 Y-box factor homolog isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"100872641 LIM domain-containing protein jub\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"100863418 LOW QUALITY PROTEIN: proline-rich nuclear receptor coactivator 2-like\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2"
					},
					{
						"name":"100862998 transportin-1\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"100868012 serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"100872457 protein SMG5 isoform X1\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"100866761 telomerase-binding protein EST1A-like isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"100872334 protein SMG7-like\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"105735721 protein TIS11\tK15308 TTP; tristetraprolin"
					},
					{
						"name":"100864557 LOW QUALITY PROTEIN: huntingtin\tK04533 HD; huntingtin"
					},
					{
						"name":"100869608 protein bicaudal C homolog 1-B isoform X1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"100868777 heterogeneous nuclear ribonucleoprotein A1, A2\/B1 homolog isoform X2\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"100867909 cAMP-dependent protein kinase catalytic subunit 1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"105734906 LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit 1-like\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"100869709 LOW QUALITY PROTEIN: la-related protein 1B\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"100865682 ataxin-2-like protein isoform X2\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"100864315 m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"100869172 mRNA-decapping enzyme 1A isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"100864525 U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"100863915 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"100863513 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"100863944 U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"100868331 U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"100870393 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"100867845 U6 snRNA-associated Sm-like protein LSm7 isoform X48\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"100868616 U6 snRNA-associated Sm-like protein LSm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"100867468 LOW QUALITY PROTEIN: unconventional myosin-Va\tK10357 MYO5; myosin V"
					},
					{
						"name":"100864365 tubulin alpha-1 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100864610 tubulin alpha-1 chain-like\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100867005 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100867486 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100868041 tubulin alpha-1C chain isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100871971 tubulin alpha-1 chain-like isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"100866445 cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100868293 cytoplasmic polyadenylation element-binding protein 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"100866056 gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5"
					},
					{
						"name":"100863913 protein Gawky isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"100870462 CCR4-NOT transcription complex subunit 1 isoform X3\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"100863547 CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"100868746 CCR4-NOT transcription complex subunit 3\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"100872105 alpha-protein kinase 1 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"100869625 CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"100871936 CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"116413865 DIS3-like exonuclease 2 isoform X1\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"100864013 PAN2-PAN3 deadenylation complex catalytic subunit PAN2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"100865909 PAN2-PAN3 deadenylation complex subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"100864375 protein BTG2-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100870913 maternal B9.10 protein\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100871167 LOW QUALITY PROTEIN: protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100868231 eukaryotic translation initiation factor 4E transporter isoform X4\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"100869686 protein PAT1 homolog 1 isoform X2\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"100870494 LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"100868547 LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"100870926 regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"100871304 LOW QUALITY PROTEIN: regulator of nonsense transcripts 3A\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"100867823 E3 ubiquitin-protein ligase TRIM71 isoform X1\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"100863476 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"100872490 YTH domain-containing family protein 3\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"100865155 nucleolysin TIAR\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"100872064 nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"100872848 polyadenylate-binding protein 1 isoform X1\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"100868029 LOW QUALITY PROTEIN: double-stranded RNA-binding protein Staufen homolog 2\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"100871882 synaptic functional regulator FMR1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"100864786 ras GTPase-activating protein-binding protein 2\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"100869994 eukaryotic translation initiation factor 2A\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"100867103 eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"100870145 eukaryotic initiation factor 4A-I\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"100870400 eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"100870171 eukaryotic translation initiation factor 4B\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"100863761 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100871147 eukaryotic translation initiation factor 4 gamma 2 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"100866816 LOW QUALITY PROTEIN: ribosomal protein S6 kinase 2 beta\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"100869296 guanine nucleotide-binding protein subunit beta-like protein\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"100864078 LOW QUALITY PROTEIN: nuclear RNA export factor 1-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100864616 LOW QUALITY PROTEIN: nuclear RNA export factor 1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105737428 nuclear RNA export factor 2-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"100864743 histone deacetylase 6 isoform X1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"100867373 tudor domain-containing protein 3 isoform X1\tK18404 TDRD3; tudor domain-containing protein 3"
					},
					{
						"name":"100872910 la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"100869172 mRNA-decapping enzyme 1A isoform X1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"100864315 m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"100871565 ATP-dependent RNA helicase me31b\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"100870494 LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"100868547 LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"100869686 protein PAT1 homolog 1 isoform X2\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"100864525 U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"100863915 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"100863513 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"100863944 U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"100868331 U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"100870393 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"100867845 U6 snRNA-associated Sm-like protein LSm7 isoform X48\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"100868616 U6 snRNA-associated Sm-like protein LSm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"100872253 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"100866745 5'-3' exoribonuclease 2 homolog\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"100868207 m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"100869440 probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"100871234 exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"100866090 LOW QUALITY PROTEIN: uncharacterized protein LOC100866090\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"100867109 exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"100869580 exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"100870436 exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"100864804 exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"100866535 exosome complex component RRP42 isoform X1\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"100869164 exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"100867292 LOW QUALITY PROTEIN: exosome complex component RRP45\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"100865777 exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"100867838 LOW QUALITY PROTEIN: exosome component 10\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"100871851 nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"100871358 M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"100868834 LOW QUALITY PROTEIN: terminal nucleotidyltransferase 4B-like\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"100869646 exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"100863116 LOW QUALITY PROTEIN: helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"100869223 LOW QUALITY PROTEIN: tetratricopeptide repeat protein 37\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"100867001 WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"100869625 CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"100870462 CCR4-NOT transcription complex subunit 1 isoform X3\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"100863547 CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"100868746 CCR4-NOT transcription complex subunit 3\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"100872105 alpha-protein kinase 1 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"100871936 CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"100865939 CCR4-NOT transcription complex subunit 9\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"100869663 CCR4-NOT transcription complex subunit 10\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"100864013 PAN2-PAN3 deadenylation complex catalytic subunit PAN2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"100865909 PAN2-PAN3 deadenylation complex subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"100865178 poly(A)-specific ribonuclease PARN-like isoform X2\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"100866276 pre-piRNA 3'-exonuclease trimmer-like isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"100867107 ATP-dependent DNA\/RNA helicase DHX36\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"100864375 protein BTG2-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100870913 maternal B9.10 protein\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100871167 LOW QUALITY PROTEIN: protein Tob1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"100868207 m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"100866209 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"100869440 probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"100867784 LOW QUALITY PROTEIN: nuclear exosome regulator NRDE2\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"100871410 protein Smaug homolog 1\tK27396 SMG; protein Smaug"
					},
					{
						"name":"100868379 LOW QUALITY PROTEIN: focadhesin\tK27498 FOCAD; focadhesin"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases",
					"children":[
					{
						"name":"100872662 LOW QUALITY PROTEIN: probable ribonuclease ZC3H12C\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"100863432 ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"100864285 probable oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					},
					{
						"name":"100867669 LOW QUALITY PROTEIN: probable oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"100869872 LOW QUALITY PROTEIN: enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"100872014 enolase-like\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"100869400 LOW QUALITY PROTEIN: polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"100869068 LOW QUALITY PROTEIN: ATP-dependent 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"100872304 heat shock 70 kDa protein cognate 5\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"100863756 heat shock protein 60A\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"100866090 LOW QUALITY PROTEIN: uncharacterized protein LOC100866090\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"100871234 exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"100869580 exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"100866535 exosome complex component RRP42 isoform X1\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}
