{
	"name":"aflr04040",
	"children":[
	{
		"name":"Ligand-gated channels",
		"children":[
		{
			"name":"GABA-A",
			"children":[
			{
				"name":"100870054 gamma-aminobutyric acid receptor alpha-like\tK05175 GABRA; gamma-aminobutyric acid receptor subunit alpha"
			},
			{
				"name":"100871232 gamma-aminobutyric acid receptor subunit alpha-5-like\tK05175 GABRA; gamma-aminobutyric acid receptor subunit alpha"
			},
			{
				"name":"100869944 gamma-aminobutyric acid receptor subunit beta-like isoform X2\tK05181 GABRB; gamma-aminobutyric acid receptor subunit beta"
			},
			{
				"name":"100871112 gamma-aminobutyric acid receptor subunit beta-like\tK05181 GABRB; gamma-aminobutyric acid receptor subunit beta"
			}
			]
		},
		{
			"name":"Glycine"
		},
		{
			"name":"Acetylcholine (nicotinic)",
			"children":[
			{
				"name":"100863009 neuronal acetylcholine receptor subunit alpha-7-like\tK04804 CHRNA2; nicotinic acetylcholine receptor alpha-2"
			},
			{
				"name":"100864296 acetylcholine receptor subunit alpha-L1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"100864636 acetylcholine receptor subunit alpha-like isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"100864818 acetylcholine receptor subunit alpha-like 1 isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"100869756 LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-10-like\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"100870093 neuronal acetylcholine receptor subunit alpha-7 isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"100870238 acetylcholine receptor subunit beta-like 2 isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"100872549 CHRNA7-FAM7A fusion protein-like isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"100872666 acetylcholine receptor subunit beta-like 1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			}
			]
		},
		{
			"name":"Serotonin (5-HT3)"
		},
		{
			"name":"Zinc-activated channel"
		},
		{
			"name":"Glutamate (ionotropic)",
			"children":[
			{
				"name":"100869823 LOW QUALITY PROTEIN: glutamate receptor 1\tK05199 GRIA3; glutamate receptor 3"
			},
			{
				"name":"100865042 ionotropic receptor 25a isoform X1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100865223 glutamate receptor ionotropic, kainate 2 isoform X1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100865697 glutamate receptor ionotropic, kainate 1 isoform X5\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100866227 LOW QUALITY PROTEIN: glutamate receptor ionotropic, kainate 2-like\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100867853 glutamate receptor ionotropic, kainate 1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100868387 ionotropic receptor 25a\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100869655 ionotropic receptor 75a-like\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100869958 LOW QUALITY PROTEIN: ionotropic receptor 93a\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100872949 LOW QUALITY PROTEIN: glutamate receptor ionotropic, delta-2\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"105736031 glutamate receptor ionotropic, kainate 2-like isoform X3\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"105737435 ionotropic receptor 75a-like\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"100867587 LOW QUALITY PROTEIN: glutamate [NMDA] receptor subunit 1\tK05208 GRIN1; glutamate receptor ionotropic, NMDA 1"
			},
			{
				"name":"100865856 glutamate receptor ionotropic, NMDA 2B isoform X1\tK05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B"
			},
			{
				"name":"100871148 LOW QUALITY PROTEIN: uncharacterized protein LOC100871148\tK05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A"
			}
			]
		},
		{
			"name":"Histamine",
			"children":[
			{
				"name":"100866427 glycine receptor subunit alpha-4 isoform X1\tK05397 HCL; histamine-gated chloride channel"
			},
			{
				"name":"100868718 glycine receptor subunit alpha-3 isoform X1\tK05397 HCL; histamine-gated chloride channel"
			}
			]
		},
		{
			"name":"Anionic glutamate",
			"children":[
			{
				"name":"100866011 glutamate-gated chloride channel isoform X1\tK05273 GRGLCN; glutamate receptor, anionic"
			}
			]
		},
		{
			"name":"Epithelial sodium channel (ENaC)"
		},
		{
			"name":"Acid-sensing ion channel (ASIC)",
			"children":[
			{
				"name":"100865614 sodium channel protein Nach-like isoform X1\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"100865834 pickpocket protein 28-like\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"100871641 pickpocket protein 28 isoform X2\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"100872717 sodium channel protein Nach-like\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"105736893 uncharacterized protein LOC105736893 isoform X1\tK03440 ASICN; acid-sensing ion channel, other"
			}
			]
		},
		{
			"name":"ATP-gated cation channel (P2X)"
		},
		{
			"name":"IP3 receptor",
			"children":[
			{
				"name":"100870897 LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor\tK04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1"
			}
			]
		}
		]
	},
	{
		"name":"Voltage-gated cation channels",
		"children":[
		{
			"name":"Sodium channel, voltage-gated (Nav)",
			"children":[
			{
				"name":"100867258 sodium channel protein para isoform X6\tK04834 SCN2A; voltage-gated sodium channel type II alpha"
			}
			]
		},
		{
			"name":"Calcium channel, voltage-gated (Cav)",
			"children":[
			{
				"name":"100865328 LOW QUALITY PROTEIN: muscle calcium channel subunit alpha-1\tK04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D"
			},
			{
				"name":"100864734 voltage-dependent T-type calcium channel subunit alpha-1G\tK04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G"
			},
			{
				"name":"100864023 voltage-dependent calcium channel subunit alpha-2\/delta-3 isoform X1\tK04860 CACNA2D3; voltage-dependent calcium channel alpha-2\/delta-3"
			},
			{
				"name":"100864137 voltage-dependent calcium channel subunit alpha-2\/delta-3 isoform X1\tK04861 CACNA2D4; voltage-dependent calcium channel alpha-2\/delta-4"
			},
			{
				"name":"100863288 voltage-dependent L-type calcium channel subunit beta-2\tK04863 CACNB2; voltage-dependent calcium channel beta-2"
			},
			{
				"name":"100869828 transmembrane protein 114\tK04870 CACNG5; voltage-dependent calcium channel gamma-5"
			},
			{
				"name":"100866963 LOW QUALITY PROTEIN: VWFA and cache domain-containing protein 1\tK28855 CACHD1; VWFA and cache domain-containing protein 1"
			}
			]
		},
		{
			"name":"Calcium channel, sperm-associated (CatSper)"
		},
		{
			"name":"Calcium channel, two-pore (TPC)",
			"children":[
			{
				"name":"100864184 two pore calcium channel protein 1 isoform X1\tK16896 TPCN1; two pore calcium channel protein 1"
			}
			]
		},
		{
			"name":"Potassium channel, voltage-gated (Kv)",
			"children":[
			{
				"name":"100864355 potassium voltage-gated channel protein Shaker isoform X1\tK04874 KCNA1; potassium voltage-gated channel Shaker-related subfamily A member 1"
			},
			{
				"name":"100866658 LOW QUALITY PROTEIN: potassium voltage-gated channel protein Shab\tK04885 KCNB1; potassium voltage-gated channel Shab-related subfamily B member 1"
			},
			{
				"name":"100869474 potassium voltage-gated channel protein Shaw-like isoform X1\tK04887 KCNC1; potassium voltage-gated channel Shaw-related subfamily C member 1"
			},
			{
				"name":"100869595 potassium voltage-gated channel protein Shaw-like isoform X3\tK04887 KCNC1; potassium voltage-gated channel Shaw-related subfamily C member 1"
			},
			{
				"name":"100870203 potassium voltage-gated channel protein Shal\tK04892 KCND2; potassium voltage-gated channel Shal-related subfamily D member 2"
			},
			{
				"name":"100866498 LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily H member 2\tK04905 KCNH2; potassium voltage-gated channel Eag-related subfamily H member 2"
			},
			{
				"name":"100869099 potassium voltage-gated channel protein eag isoform X8\tK04908 KCNH5; potassium voltage-gated channel Eag-related subfamily H member 5"
			},
			{
				"name":"100865083 potassium voltage-gated channel subfamily H member 8\tK04911 KCNH8; potassium voltage-gated channel Eag-related subfamily H member 8"
			},
			{
				"name":"100863363 potassium voltage-gated channel subfamily KQT member 1 isoform X1\tK04926 KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1"
			}
			]
		},
		{
			"name":"Potassium channel, calcium- and sodium-activated (KCa\/KNa)",
			"children":[
			{
				"name":"100867742 calcium-activated potassium channel slowpoke isoform X39\tK04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1"
			},
			{
				"name":"100863211 small conductance calcium-activated potassium channel protein-like\tK04944 KCNN3; potassium intermediate\/small conductance calcium-activated channel subfamily N member 3"
			},
			{
				"name":"100872091 potassium channel subfamily T member 2 isoform X2\tK04946 KCNT1; potassium channel subfamily T member 1"
			}
			]
		},
		{
			"name":"Potassium channel, two-pore domain (K2P)",
			"children":[
			{
				"name":"100866810 two pore potassium channel protein sup-9\tK04919 KCNK9; potassium channel subfamily K member 9"
			},
			{
				"name":"100867940 two pore potassium channel protein sup-9\tK04919 KCNK9; potassium channel subfamily K member 9"
			},
			{
				"name":"100863447 TWiK family of potassium channels protein 7\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"100866530 TWiK family of potassium channels protein 18-like isoform X2\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"100868037 TWiK family of potassium channels protein 18-like\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"100872570 uncharacterized protein LOC100872570 isoform X1\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"100872690 potassium channel subfamily K member 18 isoform X1\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"100872780 uncharacterized protein LOC100872780 isoform X1\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"105737411 TWiK family of potassium channels protein 9\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			}
			]
		},
		{
			"name":"Potassium channel, inwardly-rectifying (Kir)",
			"children":[
			{
				"name":"100871820 uncharacterized protein LOC100871820 isoform X1\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			},
			{
				"name":"100871940 uncharacterized protein LOC100871940 isoform X1\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			}
			]
		},
		{
			"name":"Transient receptor potential channel (TRP)",
			"children":[
			{
				"name":"100863924 transient receptor potential channel pyrexia-like\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"100865389 transient receptor potential cation channel protein painless\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"100867271 transient receptor potential channel pyrexia isoform X1\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"105736332 transient receptor potential channel pyrexia isoform X1\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"100865153 LOW QUALITY PROTEIN: transient receptor potential protein-like\tK04967 TRPC4; transient receptor potential cation channel subfamily C member 4"
			},
			{
				"name":"100868381 transient receptor potential-gamma protein isoform X1\tK04967 TRPC4; transient receptor potential cation channel subfamily C member 4"
			},
			{
				"name":"100871761 transient-receptor-potential-like protein\tK13803 TRPL; transient-receptor-potential-like protein"
			},
			{
				"name":"100863041 LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily V member 5\tK04974 TRPV5; transient receptor potential cation channel subfamily V member 5"
			},
			{
				"name":"100868270 uncharacterized protein LOC100868270 isoform X1\tK04975 TRPV6; transient receptor potential cation channel subfamily V member 6"
			},
			{
				"name":"100872774 transient receptor potential cation channel trpm isoform X1\tK04978 TRPM3; transient receptor potential cation channel subfamily M member 3"
			},
			{
				"name":"100866813 mucolipin-3\tK04994 MCOLN3; mucolipin 3"
			}
			]
		},
		{
			"name":"Cyclic nucleotide-gated channel (CNG)",
			"children":[
			{
				"name":"100865927 LOW QUALITY PROTEIN: uncharacterized protein LOC100865927\tK04950 CNGA3; cyclic nucleotide gated channel alpha 3"
			}
			]
		},
		{
			"name":"Cyclic nucleotide-gated channel (HCN)",
			"children":[
			{
				"name":"100863728 potassium\/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1-like\tK04955 HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2"
			},
			{
				"name":"100865854 potassium\/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 isoform X1\tK04955 HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2"
			}
			]
		},
		{
			"name":"Sodium leak channel, non-selective",
			"children":[
			{
				"name":"100864571 uncharacterized protein LOC100864571\tK21863 NALCN; sodium leak channel non-selective protein"
			},
			{
				"name":"100871312 LOW QUALITY PROTEIN: protein unc-79 homolog\tK24014 UNC79; protein unc-79"
			},
			{
				"name":"100870586 LOW QUALITY PROTEIN: protein unc-80 homolog\tK24015 UNC80; protein unc-80"
			}
			]
		},
		{
			"name":"Proton channel, voltage-gated (Hv)"
		},
		{
			"name":"Ryanodine receptor",
			"children":[
			{
				"name":"100867785 LOW QUALITY PROTEIN: ryanodine receptor\tK04962 RYR2; ryanodine receptor 2"
			}
			]
		}
		]
	},
	{
		"name":"Chloride channels",
		"children":[
		{
			"name":"Chloride channel (CLC)",
			"children":[
			{
				"name":"100872653 chloride channel protein 2 isoform X2\tK05011 CLCN2; chloride channel 2"
			},
			{
				"name":"100865041 H(+)\/Cl(-) exchange transporter 5\tK05012 CLCN3_4_5; chloride channel 3\/4\/5"
			},
			{
				"name":"100864401 H(+)\/Cl(-) exchange transporter 7 isoform X1\tK05016 CLCN7; chloride channel 7"
			}
			]
		},
		{
			"name":"Chloride channel, intracellular (CLIC)",
			"children":[
			{
				"name":"100871618 chloride intracellular channel exc-4\tK05022 CLIC2; chloride intracellular channel protein 2"
			}
			]
		},
		{
			"name":"Chloride channel, calcium-activated (CaCC)",
			"children":[
			{
				"name":"100863866 anoctamin-4-like\tK19496 ANO1; anoctamin-1"
			},
			{
				"name":"100866390 LOW QUALITY PROTEIN: anoctamin-4\tK19499 ANO4; anoctamin-4"
			},
			{
				"name":"100872409 anoctamin-8 isoform X2\tK19502 ANO8; anoctamin-8"
			}
			]
		},
		{
			"name":"Chloride channel, volume-regulated (VRAC)"
		},
		{
			"name":"Maxi chloride channel (VDAC)",
			"children":[
			{
				"name":"105734832 voltage-dependent anion-selective channel protein 1-like\tK05862 VDAC1; voltage-dependent anion channel protein 1"
			},
			{
				"name":"100867899 voltage-dependent anion-selective channel\tK15040 VDAC2; voltage-dependent anion channel protein 2"
			}
			]
		}
		]
	},
	{
		"name":"Other channels",
		"children":[
		{
			"name":"Calcium channel, calcium release-activated (Orai)",
			"children":[
			{
				"name":"100867988 calcium release-activated calcium channel protein 1\tK16056 ORAI1; calcium release-activated calcium channel protein 1"
			},
			{
				"name":"100868939 calcium release-activated calcium channel protein 1-like\tK16056 ORAI1; calcium release-activated calcium channel protein 1"
			}
			]
		},
		{
			"name":"Mechanosensitive channel (Piezo)",
			"children":[
			{
				"name":"100870612 LOW QUALITY PROTEIN: piezo-type mechanosensitive ion channel component\tK22128 PIEZO1_2; piezo-type mechanosensitive ion channel component 1\/2"
			}
			]
		}
		]
	}
	]
}