{
	"name":"afv03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"AFLA_011467 hypothetical protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"AFLA_012865 hypothetical protein\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"AFLA_001231 hypothetical protein\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"AFLA_003047 hypothetical protein\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"AFLA_004891 hypothetical protein\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"AFLA_001573 hypothetical protein\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"AFLA_010566 hypothetical protein\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"AFLA_011626 hypothetical protein\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"AFLA_011601 hypothetical protein\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"AFLA_006578 hypothetical protein\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"AFLA_004115 hypothetical protein\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"AFLA_012871 hypothetical protein\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"AFLA_010578 hypothetical protein\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"AFLA_008189 hypothetical protein\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"AFLA_005732 hypothetical protein\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"AFLA_001905 hypothetical protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"AFLA_001338 hypothetical protein\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"AFLA_001399 hypothetical protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"AFLA_005801 hypothetical protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"AFLA_010715 hypothetical protein\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"AFLA_010686 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"AFLA_009613 hypothetical protein\tK10609 CUL4; cullin 4"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"AFLA_005452 hypothetical protein\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"AFLA_001198 hypothetical protein\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"AFLA_009051 hypothetical protein\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"AFLA_005956 hypothetical protein\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"AFLA_004298 hypothetical protein\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"AFLA_002169 hypothetical protein\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"AFLA_000872 hypothetical protein\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"AFLA_003426 hypothetical protein\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"AFLA_005553 hypothetical protein\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"AFLA_008240 hypothetical protein\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"AFLA_000656 hypothetical protein\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"AFLA_010686 hypothetical protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"AFLA_009613 hypothetical protein\tK10609 CUL4; cullin 4"
						},
						{
							"name":"AFLA_000400 hypothetical protein\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"AFLA_007740 hypothetical protein\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"AFLA_010652 hypothetical protein\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"AFLA_011963 hypothetical protein\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"AFLA_002205 hypothetical protein\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"AFLA_000621 hypothetical protein\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"AFLA_012074 hypothetical protein\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"AFLA_005621 hypothetical protein\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"AFLA_012970 hypothetical protein\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"AFLA_005081 hypothetical protein\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"AFLA_005441 hypothetical protein\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"AFLA_004784 hypothetical protein\tK06634 CCNH; cyclin H"
					},
					{
						"name":"AFLA_006984 hypothetical protein\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"AFLA_012886 hypothetical protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"AFLA_006848 hypothetical protein\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"AFLA_000329 hypothetical protein\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"AFLA_007321 hypothetical protein\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"AFLA_009354 hypothetical protein\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"AFLA_004376 hypothetical protein\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"AFLA_008189 hypothetical protein\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"AFLA_003419 hypothetical protein\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"AFLA_004462 hypothetical protein\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"AFLA_013514 hypothetical protein\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"AFLA_001590 hypothetical protein\tK03869 CUL3; cullin 3"
					},
					{
						"name":"AFLA_006582 hypothetical protein\tK03872 ELOC; elongin-C"
					},
					{
						"name":"AFLA_008280 hypothetical protein\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"AFLA_004080 hypothetical protein\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"AFLA_002917 hypothetical protein\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"AFLA_007072 hypothetical protein\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"AFLA_009505 hypothetical protein\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"AFLA_007290 hypothetical protein\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"AFLA_011626 hypothetical protein\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"AFLA_011601 hypothetical protein\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"AFLA_006578 hypothetical protein\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"AFLA_012886 hypothetical protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"AFLA_006848 hypothetical protein\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"AFLA_005860 hypothetical protein\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"AFLA_004259 hypothetical protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"AFLA_004523 hypothetical protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"AFLA_000338 hypothetical protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"AFLA_005863 hypothetical protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"AFLA_004186 hypothetical protein\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"AFLA_008189 hypothetical protein\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"AFLA_011168 hypothetical protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"AFLA_006815 hypothetical protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"AFLA_011063 hypothetical protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"AFLA_006815 hypothetical protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"AFLA_011063 hypothetical protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"AFLA_008867 hypothetical protein\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"AFLA_008867 hypothetical protein\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"AFLA_008571 hypothetical protein\tK10958 RAD57; DNA repair protein RAD57"
					}
					]
				},
				{
					"name":"Rad52 family proteins"
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"AFLA_001281 hypothetical protein\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"AFLA_004033 hypothetical protein\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"AFLA_001389 hypothetical protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"AFLA_001389 hypothetical protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"AFLA_005678 hypothetical protein\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"AFLA_004207 hypothetical protein\tK15364 NCE4; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"AFLA_012886 hypothetical protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"AFLA_006848 hypothetical protein\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"Protein phosphatase 4"
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"AFLA_009377 hypothetical protein\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"AFLA_009247 hypothetical protein\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"AFLA_001514 hypothetical protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"AFLA_010234 hypothetical protein\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"AFLA_009673 hypothetical protein\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"AFLA_002562 hypothetical protein\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"AFLA_008874 hypothetical protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"AFLA_010720 hypothetical protein\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"AFLA_001196 hypothetical protein\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"AFLA_011980 hypothetical protein\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"AFLA_002521 hypothetical protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"AFLA_000518 hypothetical protein\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"AFLA_001322 hypothetical protein\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"AFLA_003640 hypothetical protein\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"AFLA_003621 hypothetical protein\tK14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"AFLA_005201 hypothetical protein\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"AFLA_005684 hypothetical protein\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"AFLA_006815 hypothetical protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"AFLA_011063 hypothetical protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"AFLA_009543 hypothetical protein\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"AFLA_011801 hypothetical protein\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"AFLA_008206 hypothetical protein\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					},
					{
						"name":"AFLA_008859 hypothetical protein\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"AFLA_001905 hypothetical protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"AFLA_000795 hypothetical protein\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"AFLA_006055 hypothetical protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"AFLA_008634 hypothetical protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"AFLA_006868 hypothetical protein\tK11511 APITD1; centromere protein S"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"AFLA_001389 hypothetical protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"AFLA_005678 hypothetical protein\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"AFLA_004207 hypothetical protein\tK15364 NCE4; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"AFLA_003052 hypothetical protein\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"AFLA_008867 hypothetical protein\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"AFLA_006073 hypothetical protein\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"AFLA_009519 hypothetical protein\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"AFLA_006559 hypothetical protein\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"AFLA_004782 hypothetical protein\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"AFLA_011168 hypothetical protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"AFLA_010187 hypothetical protein\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"AFLA_013750 hypothetical protein\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"AFLA_012640 hypothetical protein\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"AFLA_010348 hypothetical protein\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"AFLA_013126 hypothetical protein\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"AFLA_011602 hypothetical protein\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"AFLA_009603 hypothetical protein\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"AFLA_004693 hypothetical protein\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"AFLA_000667 hypothetical protein\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"AFLA_009345 hypothetical protein\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"AFLA_011182 hypothetical protein\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"AFLA_007962 hypothetical protein\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"AFLA_004646 hypothetical protein\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"AFLA_011033 hypothetical protein\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"AFLA_014278 hypothetical protein\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"AFLA_004259 hypothetical protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"AFLA_004523 hypothetical protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"AFLA_000338 hypothetical protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"AFLA_005863 hypothetical protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"AFLA_011033 hypothetical protein\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"AFLA_012972 hypothetical protein\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"AFLA_013014 hypothetical protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"AFLA_007843 hypothetical protein\tK11272 MRC1; mediator of replication checkpoint protein 1"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"AFLA_006073 hypothetical protein\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"AFLA_008190 hypothetical protein\tK20403 TTI1; TELO2-interacting protein 1"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"AFLA_000327 hypothetical protein\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"AFLA_004521 hypothetical protein\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"AFLA_013018 hypothetical protein\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"AFLA_009611 hypothetical protein\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"AFLA_001250 hypothetical protein\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"AFLA_001588 hypothetical protein\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"AFLA_001645 hypothetical protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"AFLA_009479 hypothetical protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"AFLA_008319 hypothetical protein\tK03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]"
				},
				{
					"name":"AFLA_000926 hypothetical protein\tK24664 FKH; forkhead protein FKH"
				},
				{
					"name":"AFLA_004123 hypothetical protein\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"AFLA_001308 hypothetical protein\tK25059 SDE2; replication stress response regulator SDE2"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"AFLA_001585 hypothetical protein\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"AFLA_002022 hypothetical protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"AFLA_002211 hypothetical protein\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"AFLA_008419 hypothetical protein\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"AFLA_009429 hypothetical protein\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"AFLA_009706 hypothetical protein\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"AFLA_012798 hypothetical protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"AFLA_012561 hypothetical protein\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"AFLA_008830 hypothetical protein\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"AFLA_000649 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"AFLA_008826 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"AFLA_003592 hypothetical protein\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"AFLA_007271 hypothetical protein\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"AFLA_009572 hypothetical protein\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"AFLA_011467 hypothetical protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"AFLA_012865 hypothetical protein\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"AFLA_007260 hypothetical protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"AFLA_000646 hypothetical protein\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"AFLA_004891 hypothetical protein\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"AFLA_004341 hypothetical protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"AFLA_004341 hypothetical protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"AFLA_000649 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"AFLA_008826 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"AFLA_003592 hypothetical protein\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}