{
	"name":"afz03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"127552211 methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"127545594 DNA oxidative demethylase ALKBH2\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"127539676 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"127562035 LOW QUALITY PROTEIN: activating signal cointegrator 1 complex subunit 3\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"127554181 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"127545593 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127550380 cyclin-O\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"127537907 G\/T mismatch-specific thymine DNA glycosylase isoform X1\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"127542822 DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"127539142 single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"127563418 adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"127552216 methyl-CpG-binding domain protein 4 isoform X1\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"127551750 N-glycosylase\/DNA lyase isoform X1\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127551964 endonuclease 8-like 1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127548522 endonuclease 8-like 2\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127539862 endonuclease 8-like 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127543424 endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"127549142 DNA-(apurinic or apyrimidinic site) endonuclease\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"127542477 DNA-(apurinic or apyrimidinic site) endonuclease 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"127556834 DNA polymerase delta catalytic subunit isoform X1\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"127548837 DNA polymerase delta subunit 2\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"127555083 DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"127541297 DNA polymerase delta subunit 4 isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"127545349 DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"127549685 DNA polymerase epsilon subunit 2\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"127550801 DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"127548207 DNA polymerase epsilon subunit 4\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"127548185 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"127541865 flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"127556601 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"127548273 DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"127556406 DNA repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"127558992 DNA ligase 3 isoform X1\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"127549415 tyrosyl-DNA phosphodiesterase 1 isoform X1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"127560706 aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"127548163 LOW QUALITY PROTEIN: aprataxin and PNK-like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"127556599 bifunctional polynucleotide phosphatase\/kinase\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"127554697 high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"127557048 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"127551498 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"127559548 poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"127549147 poly [ADP-ribose] polymerase 2 isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"127554154 protein mono-ADP-ribosyltransferase PARP3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"127554770 protein mono-ADP-ribosyltransferase PARP4 isoform X1\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"127552426 DNA repair protein complementing XP-C cells isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"127542093 homeodomain-only protein isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"127544805 UV excision repair protein RAD23 homolog A\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"127554935 UV excision repair protein RAD23 homolog B isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"127541983 centrin-1-like\tK10840 CETN2; centrin-2"
						},
						{
							"name":"127542911 centrin-2 isoform X1\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"127538369 E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"127543030 cullin-4B isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127553488 cullin-4A isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127563077 LOW QUALITY PROTEIN: cullin-4B-like\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127539823 DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"127541912 DNA damage-binding protein 2\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"127560880 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"127540426 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"127550751 DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"127559362 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB3-like\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"127554284 DNA-directed RNA polymerase II subunit RPB4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"127545098 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"127538269 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"127540298 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"127540451 DNA-directed RNA polymerases I, II, and III subunit RPABC3-like\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"127563453 DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"127556052 DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"127539613 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"127558642 DNA-directed RNA polymerase II subunit RPB11-a\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"127544331 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						},
						{
							"name":"127553521 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"127538369 E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"127543030 cullin-4B isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127553488 cullin-4A isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127563077 LOW QUALITY PROTEIN: cullin-4B-like\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127539823 DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"127557771 DNA excision repair protein ERCC-8\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"127551798 DNA excision repair protein ERCC-6\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"127539787 LOW QUALITY PROTEIN: UV-stimulated scaffold protein A\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"127544777 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"127554295 general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"127556321 general transcription and DNA repair factor IIH helicase subunit XPD isoform X1\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"127541268 general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"127548563 LOW QUALITY PROTEIN: general transcription factor IIH subunit 1-like\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"127559045 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"127545396 general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"127561044 general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"127562368 general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"127558341 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"127559402 cyclin-H\tK06634 CCNH; cyclin H"
					},
					{
						"name":"127549594 CDK-activating kinase assembly factor MAT1 isoform X1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"127558830 replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"127555614 replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"127539300 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"127560815 DNA repair protein complementing XP-A cells\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"127556320 DNA excision repair protein ERCC-1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"127539061 LOW QUALITY PROTEIN: DNA repair endonuclease XPF\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"127553430 DNA excision repair protein ERCC-5\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"127556601 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"127551744 MMS19 nucleotide excision repair protein homolog isoform X1\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"127545637 coiled-coil domain-containing protein 117\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"127548370 probable cytosolic iron-sulfur protein assembly protein CIAO1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"127547935 cytosolic iron-sulfur assembly component 2B\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"127551281 cytosolic iron-sulfur assembly component 2A\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"127553040 cullin-3 isoform X1\tK03869 CUL3; cullin 3"
					},
					{
						"name":"127554954 cullin-5\tK10612 CUL5; cullin 5"
					},
					{
						"name":"127543762 elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"127543086 elongin-A-like\tK15076 ELOA; elongin-A"
					},
					{
						"name":"127551994 elongin-A-like\tK15076 ELOA; elongin-A"
					},
					{
						"name":"127552218 elongin-A-like\tK15076 ELOA; elongin-A"
					},
					{
						"name":"127555703 elongin-A isoform X1\tK15076 ELOA; elongin-A"
					},
					{
						"name":"127559860 ubiquitin-associated protein 2-like isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"127561814 ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"127548059 LOW QUALITY PROTEIN: DNA mismatch repair protein Msh2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"127559152 DNA mismatch repair protein Msh3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"127548062 DNA mismatch repair protein Msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"127554471 PMS1 protein homolog 1 isoform X1\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"127564365 mismatch repair endonuclease PMS2\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"127549485 DNA mismatch repair protein Mlh3 isoform X1\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"127556834 DNA polymerase delta catalytic subunit isoform X1\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"127548837 DNA polymerase delta subunit 2\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"127555083 DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"127541297 DNA polymerase delta subunit 4 isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"127558830 replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"127555614 replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"127539300 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"127540303 replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"127552928 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"127558705 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"127545526 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"127554676 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"127548185 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"127559600 exonuclease 1 isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"127554697 high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"127557048 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"127556601 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"127549314 WD repeat-containing protein 76\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"127549849 DNA repair protein RAD50-like isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"127544265 nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"127560081 LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"127553145 BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"127560081 LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"127541128 BRCA1-A complex subunit Abraxas 1 isoform X1\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"127542604 BRCA1-A complex subunit Abraxas 1-like isoform X1\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"127550269 BRCA1-A complex subunit RAP80 isoform X1\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"127545074 BRISC and BRCA1-A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"127548707 BRISC and BRCA1-A complex member 2 isoform X1\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"127542950 lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					},
					{
						"name":"127559273 lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"127560081 LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"127559949 Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"127538868 DNA topoisomerase 2-binding protein 1 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"127560081 LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"127543956 DNA endonuclease RBBP8 isoform X1\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"127553349 LOW QUALITY PROTEIN: DNA endonuclease RBBP8-like\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"127549849 DNA repair protein RAD50-like isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"127544265 nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"127560081 LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"127554686 breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"127540097 partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"127549238 DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"127549238 DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"127549664 DNA repair protein RAD51 homolog 2\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"127559977 DNA repair protein RAD51 homolog 3\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"127558995 DNA repair protein RAD51 homolog 4 isoform X1\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"127539150 DNA repair protein XRCC2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"127549875 DNA repair protein XRCC3\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"127564617 DNA repair protein RAD52 homolog\tK10873 RAD52; DNA repair and recombination protein RAD52"
					},
					{
						"name":"127560377 RAD52 motif-containing protein 1\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"127563394 DNA repair and recombination protein RAD54-like isoform X1\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"127554252 helicase ARIP4 isoform X1\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"127544285 DNA repair and recombination protein RAD54B\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"127538904 ATP-dependent DNA helicase Q1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"127541885 bifunctional 3'-5' exonuclease\/ATP-dependent helicase WRN isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"127551416 recQ-like DNA helicase BLM\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"127544581 ATP-dependent DNA helicase Q4\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"127560466 ATP-dependent DNA helicase Q5 isoform X1\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"127551416 recQ-like DNA helicase BLM\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"127545792 LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127541096 recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"127539211 recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"127558830 replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"127555614 replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"127539300 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"127556105 serine\/threonine-protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"127544016 serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"127546568 serine\/threonine-protein phosphatase 4 regulatory subunit 1-like\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"127551282 serine\/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"127548096 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 4 regulatory subunit 3B\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"127549404 serine\/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"127549402 serine\/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"127540742 AP-5 complex subunit beta-1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"127549563 AP-5 complex subunit mu-1 isoform X1\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"127547415 AP-5 complex subunit sigma-1\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					},
					{
						"name":"127563572 AP-5 complex subunit zeta-1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"127538317 structural maintenance of chromosomes protein 5\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"127542405 structural maintenance of chromosomes protein 6-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"127542468 structural maintenance of chromosomes protein 6-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"127542767 structural maintenance of chromosomes protein 6-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"127542904 structural maintenance of chromosomes protein 6-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"127547298 structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"127547310 protein LRATD1 isoform X1\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"127555711 non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"127544444 E3 SUMO-protein ligase NSE2\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"127564191 non-structural maintenance of chromosomes element 3 homolog\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"127551653 non-structural maintenance of chromosomes element 4 homolog A isoform X1\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"127559784 SMC5-SMC6 complex localization factor protein 1\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"127551481 SMC5-SMC6 complex localization factor protein 2 isoform X1\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"127550251 SUMO-interacting motif-containing protein 1\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"127560065 crossover junction endonuclease EME1 isoform X1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"127549674 exonuclease 3'-5' domain-containing protein 2 isoform X1\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"127541804 crossover junction endonuclease MUS81\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"127564161 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"127550850 DNA repair protein SWI5 homolog\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"127551553 swi5-dependent recombination DNA repair protein 1 homolog\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"127556049 structure-specific endonuclease subunit SLX1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"127542234 structure-specific endonuclease subunit SLX4 isoform X1\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"127547299 flap endonuclease GEN homolog 1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"127549322 spatacsin\tK19026 SPG11; spatacsin"
					},
					{
						"name":"127549663 zinc finger FYVE domain-containing protein 26\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"127564144 RAD51-associated protein 1 isoform X1\tK20778 RAD51AP1; RAD51-associated protein 1"
					},
					{
						"name":"127562646 nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 isoform X1\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"127550790 mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"127552037 mortality factor 4-like protein 1 isoform X1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"127557726 mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"127564360 mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"127550384 deoxynucleoside triphosphate triphosphohydrolase SAMHD1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"127553478 fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"127543892 DNA repair-scaffolding protein\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"127544449 protein LRATD2\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"127563733 BRCA1-associated ATM activator 1\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"127562456 cilia- and flagella-associated protein 410 isoform X1\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"127544931 hepatoma-derived growth factor-related protein 2 isoform X1\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"127558777 zinc finger SWIM domain-containing protein 7\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"127544768 ATPase SWSAP1\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"127555052 BRCA2-interacting transcriptional repressor EMSY isoform X1\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"127553795 heat shock factor 2-binding protein\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"127562021 protein MMS22-like\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"127544591 tonsoku-like protein isoform X1\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"127541276 biorientation of chromosomes in cell division protein 1-like 1 isoform X1\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"127537814 PCNA-interacting partner\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"127561360 LOW QUALITY PROTEIN: homologous recombination OB-fold protein\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"127548509 DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"127562154 DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"127556220 heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"127541772 heterogeneous nuclear ribonucleoprotein U-like protein 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"127554581 RNA-binding protein 6 isoform X1\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"127538430 X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"127553134 X-ray repair cross-complementing protein 5\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"127543891 DNA-dependent protein kinase catalytic subunit\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"127549849 DNA repair protein RAD50-like isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"127553453 DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"127559297 DNA repair protein XRCC4 isoform X1\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"127553087 non-homologous end-joining factor 1 isoform X1\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"127551498 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"127547613 DNA-directed DNA\/RNA polymerase mu\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"127547151 DNA nucleotidylexotransferase\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"127548273 DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"127560706 aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"127548163 LOW QUALITY PROTEIN: aprataxin and PNK-like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"127564118 protein artemis isoform X1\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"127544104 tyrosyl-DNA phosphodiesterase 2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"127543982 structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"127545115 PWWP domain-containing DNA repair factor 3A isoform X1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"127549116 protein PAXX\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"127564181 cell cycle regulator of non-homologous end joining\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"127543112 jmjC domain-containing protein 8 isoform X1\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"127548514 shieldin complex subunit 1\tK26128 SHLD1; shieldin complex subunit 1"
					},
					{
						"name":"127551784 shieldin complex subunit 2 isoform X1\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"127558141 shieldin complex subunit 3\tK26130 SHLD3; shieldin complex subunit 3"
					},
					{
						"name":"127540396 BEN domain-containing protein 4\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"127538409 non-homologous end joining factor IFFO1 isoform X1\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"127555774 intermediate filament family orphan 2 isoform X1\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"127546407 Fanconi anemia group A protein\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"127553626 Fanconi anemia group B protein isoform X1\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"127561706 Fanconi anemia group C protein\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"127561177 Fanconi anemia group E protein\tK10892 FANCE; fanconi anemia group E protein"
					},
					{
						"name":"127540449 Fanconi anemia group F protein\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"127540612 Fanconi anemia group G protein isoform X1\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"127548104 E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"127549550 Fanconi anemia group M protein\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"127550641 Fanconi anemia core complex-associated protein 24\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"127560649 Fanconi anemia core complex-associated protein 100\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"127556038 transcription factor HES-4\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"127558308 transcription factor HES-1\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"127555891 centromere protein S isoform X1\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"127560618 centromere protein X\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"127562718 ubiquitin-conjugating enzyme E2 T isoform X1\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					},
					{
						"name":"127562786 ubiquitin-conjugating enzyme E2 T-like\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"127551416 recQ-like DNA helicase BLM\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"127545792 LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127541096 recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"127539211 recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"127551874 Fanconi anemia group D2 protein isoform X1\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"127551386 Fanconi anemia group I protein\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"127560081 LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"127554686 breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"127559949 Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"127540097 partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"127551320 fanconi-associated nuclease 1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"127549238 DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"127559977 DNA repair protein RAD51 homolog 3\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"127543374 telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"127563220 ubiquitin carboxyl-terminal hydrolase 1 isoform X1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"127550407 WD repeat-containing protein 48 isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"127550581 serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"127556705 serine\/threonine-protein phosphatase 6 regulatory subunit 1 isoform X1\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"127538829 serine\/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"127541841 serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"127539115 serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"127554440 serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"127539093 serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"127561624 E3 ubiquitin-protein ligase RNF8 isoform X1\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"127554195 E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"127555081 E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"127553716 E3 ubiquitin-protein ligase HERC2 isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"127560869 telomerase Cajal body protein 1 isoform X1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"127549076 taperin\tK24164 TPRN; taperin"
					},
					{
						"name":"127560986 zinc finger CW-type PWWP domain protein 1 isoform X1\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"127538764 WD repeat-containing protein 70-like\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"127556702 WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"127549314 WD repeat-containing protein 76\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"127553023 abasic site processing protein HMCES\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"127561788 DNA polymerase eta\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"127543485 DNA polymerase iota isoform X1\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"127558797 DNA polymerase kappa\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"127553746 DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"127562099 DNA polymerase zeta catalytic subunit\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase",
				"children":[
				{
					"name":"127541500 DNA polymerase nu\tK16618 POLN; DNA polymerase nu [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"127543042 ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"127549821 ubiquitin-conjugating enzyme E2 B isoform X1\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"127551587 E3 ubiquitin-protein ligase RAD18 isoform X1\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"127552963 helicase-like transcription factor isoform X1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"127543888 ubiquitin-conjugating enzyme E2 variant 2 isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"127548906 ubiquitin-conjugating enzyme E2 variant 1 isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"127539451 ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"127547978 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"127548185 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"127551279 PCNA-associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"127537814 PCNA-interacting partner\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"127559663 DNA-dependent metalloprotease SPRTN isoform X1\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"127542688 germ cell nuclear acidic protein\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"127541292 cell cycle checkpoint control protein RAD9A\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"127548486 cell cycle checkpoint control protein RAD9B\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"127553609 checkpoint protein HUS1 isoform X1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"127556462 cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"127559062 cell cycle checkpoint protein RAD17\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"127552928 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"127558705 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"127545526 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"127554676 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"127556462 cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"127564518 protein timeless homolog\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"127551244 TIMELESS-interacting protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"127555406 claspin\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"127543374 telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"127550420 LOW QUALITY PROTEIN: TELO2-interacting protein 1 homolog\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"127548211 TELO2-interacting protein 2\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"127561062 large proline-rich protein BAG6 isoform X1\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"127542466 ubiquitin-like protein 4A\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"127562552 ubiquitin-like protein 4B\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"127564182 Golgi to ER traffic protein 4 homolog isoform X1\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"127559881 integrator complex subunit 3 isoform X1\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"127538911 SOSS complex subunit B1 isoform X1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"127554456 SOSS complex subunit B2 isoform X1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"127537932 SOSS complex subunit C isoform X1\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"127552991 serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"127548152 ewing's tumor-associated antigen 1\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"127554958 serine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"127560870 cellular tumor antigen p53 isoform X1\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"127554847 serine\/threonine-protein kinase Chk1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"127545635 serine\/threonine-protein kinase Chk2 isoform X1\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"127547413 M-phase inducer phosphatase 2\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"127549958 M-phase inducer phosphatase 3\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"127544337 14-3-3 protein zeta\/delta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127548618 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127548860 14-3-3 protein beta\/alpha\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127545717 14-3-3 protein eta isoform X1\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"127558652 14-3-3 protein gamma\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"127558846 14-3-3 protein epsilon isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"127540764 neuron navigator 2 isoform X1\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"127539628 LOW QUALITY PROTEIN: wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"127564221 wee1-like protein kinase 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"127560849 period circadian protein homolog 1 isoform X1\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"127563159 period circadian protein homolog 2 isoform X1\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"127555914 period circadian protein homolog 3 isoform X1\tK21945 PER3; period circadian protein 3"
				},
				{
					"name":"127561032 mediator of DNA damage checkpoint protein 1 isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"127543228 plastin-3 isoform X1\tK17336 PLS3; plastin-3"
				},
				{
					"name":"127551378 apoptosis-enhancing nuclease isoform X1\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"127563414 serine\/threonine-protein kinase PLK3 isoform X1\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"127545128 inactive serine\/threonine-protein kinase PLK5\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"127541207 serine\/threonine-protein kinase Nek1 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"127553863 serine\/threonine-protein kinase Nek4 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"127554607 LOW QUALITY PROTEIN: serine\/threonine-protein kinase Nek4-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"127557386 serine\/threonine-protein kinase Nek5\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"127564037 serine\/threonine-protein kinase Nek10\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"127538900 serine\/threonine-protein kinase Nek11 isoform X1\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"127553856 protein downstream neighbor of Son\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"127538545 KN motif and ankyrin repeat domain-containing protein 1 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"127544758 KN motif and ankyrin repeat domain-containing protein 2 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"127545296 KN motif and ankyrin repeat domain-containing protein 3\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"127563222 LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 4\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"127558999 schlafen family member 11\tK24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]"
				},
				{
					"name":"127543719 charged multivesicular body protein 4c\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"127543681 vacuolar protein sorting-associated protein 4B\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"127547740 vacuolar protein sorting-associated protein 4A\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"127549239 abscission\/NoCut checkpoint regulator isoform X1\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"127559540 replication stress response regulator SDE2\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"127550416 bladder cancer-associated protein\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"127554121 DNA polymerase theta\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"127558280 myb-binding protein 1A\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"127541217 DNA-directed primase\/polymerase protein\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"127542323 three prime repair exonuclease 2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"127551596 DNA cross-link repair 1A protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"127559296 5' exonuclease Apollo isoform X1\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"127558809 LOW QUALITY PROTEIN: exonuclease V\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"127560667 endonuclease V isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"127557241 DNA annealing helicase and endonuclease ZRANB3-like\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"127545075 ankyrin repeat and LEM domain-containing protein 1 isoform X1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"127541127 helicase POLQ-like\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"127561682 DNA excision repair protein ERCC-6-like 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"127540851 pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"127537805 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"127561807 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"127559286 pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"127540283 pleiotropic regulator 1\tK12862 PLRG1; pleiotropic regulator 1"
				},
				{
					"name":"127554892 pleiotropic regulator 1-like\tK12862 PLRG1; pleiotropic regulator 1"
				},
				{
					"name":"127558055 pleiotropic regulator 1-like\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"127555187 nucleotide triphosphate diphosphatase NUDT15 isoform X1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"127563931 oxidized purine nucleoside triphosphate hydrolase isoform X1\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"127548314 8-oxo-dGDP phosphatase NUDT18 isoform X1\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"127551128 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"127555272 ribonucleoside-diphosphate reductase large subunit isoform X1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"127544345 ribonucleoside-diphosphate reductase subunit M2 B isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"127548691 ribonucleoside-diphosphate reductase subunit M2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"127552211 methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"127554181 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"127545593 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127539142 single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"127542822 DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"127563418 adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"127543424 endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"127564572 single-stranded DNA-binding protein, mitochondrial isoform X1\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"127564572 single-stranded DNA-binding protein, mitochondrial isoform X1\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"127555187 nucleotide triphosphate diphosphatase NUDT15 isoform X1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"127551128 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}