{
	"name":"aga04040",
	"children":[
	{
		"name":"Ligand-gated channels",
		"children":[
		{
			"name":"GABA-A",
			"children":[
			{
				"name":"1270594 gamma-aminobutyric acid receptor alpha-like\tK05175 GABRA; gamma-aminobutyric acid receptor subunit alpha"
			},
			{
				"name":"4576034 gamma-aminobutyric acid receptor subunit alpha-6 isoform X2\tK05175 GABRA; gamma-aminobutyric acid receptor subunit alpha"
			},
			{
				"name":"1272239 gamma-aminobutyric acid receptor subunit beta-like\tK05181 GABRB; gamma-aminobutyric acid receptor subunit beta"
			},
			{
				"name":"1276697 gamma-aminobutyric acid receptor subunit beta isoform X1\tK05181 GABRB; gamma-aminobutyric acid receptor subunit beta"
			}
			]
		},
		{
			"name":"Glycine"
		},
		{
			"name":"Acetylcholine (nicotinic)",
			"children":[
			{
				"name":"1269406 neuronal acetylcholine receptor subunit alpha-7 isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1270457 neuronal acetylcholine receptor subunit alpha-7\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1270461 acetylcholine receptor subunit beta-like 1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1271417 acetylcholine receptor subunit alpha-like 1 isoform X2\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1271929 acetylcholine receptor subunit alpha-like isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1272129 acetylcholine receptor subunit alpha-like isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1272986 acetylcholine receptor subunit alpha-like 1 isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1272988 acetylcholine receptor subunit alpha-like 2\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1272992 acetylcholine receptor subunit beta-like 2\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1275447 neuronal acetylcholine receptor subunit alpha-7\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"133393676 neuronal acetylcholine receptor subunit alpha-4-like isoform X1\tK05312 CHRNN; nicotinic acetylcholine receptor, invertebrate"
			},
			{
				"name":"1279487 neuronal acetylcholine receptor subunit non-alpha-3\tK04814 CHRNB3; nicotinic acetylcholine receptor beta-3"
			}
			]
		},
		{
			"name":"Serotonin (5-HT3)"
		},
		{
			"name":"Zinc-activated channel"
		},
		{
			"name":"Glutamate (ionotropic)",
			"children":[
			{
				"name":"1276693 glutamate receptor 1 isoform X1\tK05199 GRIA3; glutamate receptor 3"
			},
			{
				"name":"1269730 glutamate receptor ionotropic, kainate 3\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1270566 glutamate receptor ionotropic, kainate 2\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1272000 ionotropic receptor 93a\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1272393 glutamate receptor ionotropic, kainate 2 isoform X1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1273165 glutamate receptor ionotropic, kainate 2 isoform X1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1276160 ionotropic receptor 75a\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1279695 ionotropic receptor 25a\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1280702 glutamate receptor ionotropic, delta-1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1281300 ionotropic receptor 75a\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"3289757 glutamate receptor ionotropic, kainate 2 isoform X2\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"4576020 glutamate receptor ionotropic, kainate 2 isoform X1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"4576285 glutamate receptor 1\tK05313 GRIN; glutamate receptor, ionotropic, invertebrate"
			},
			{
				"name":"1281696 glutamate [NMDA] receptor subunit 1\tK05208 GRIN1; glutamate receptor ionotropic, NMDA 1"
			},
			{
				"name":"1275196 glutamate receptor ionotropic, NMDA 2B isoform X1\tK05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B"
			},
			{
				"name":"1276211 uncharacterized protein LOC1276211 isoform X1\tK05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A"
			}
			]
		},
		{
			"name":"Histamine",
			"children":[
			{
				"name":"11175937 glycine receptor subunit alpha-2\tK05397 HCL; histamine-gated chloride channel"
			},
			{
				"name":"1281130 glycine receptor subunit alpha-2\tK05397 HCL; histamine-gated chloride channel"
			}
			]
		},
		{
			"name":"Anionic glutamate",
			"children":[
			{
				"name":"4577187 glutamate-gated chloride channel isoform X1\tK05273 GRGLCN; glutamate receptor, anionic"
			}
			]
		},
		{
			"name":"Epithelial sodium channel (ENaC)"
		},
		{
			"name":"Acid-sensing ion channel (ASIC)",
			"children":[
			{
				"name":"1270353 pickpocket protein 11\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1270822 pickpocket protein 28\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1272421 sodium channel protein Nach\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1272617 sodium channel protein Nach\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1277353 sodium channel protein Nach\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1277603 sodium channel protein Nach\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1278009 sodium channel protein Nach\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1278964 sodium channel protein Nach\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1280409 pickpocket protein 28\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1281021 pickpocket protein 28\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1281022 pickpocket protein 28\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1281540 pickpocket protein 28\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"1281572 pickpocket protein 28 isoform X1\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"133393161 pickpocket protein 28-like\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"133393163 pickpocket protein 28-like\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"133393795 pickpocket protein 28-like\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"3291330 pickpocket protein 28\tK03440 ASICN; acid-sensing ion channel, other"
			},
			{
				"name":"4577657 pickpocket protein 28\tK03440 ASICN; acid-sensing ion channel, other"
			}
			]
		},
		{
			"name":"ATP-gated cation channel (P2X)"
		},
		{
			"name":"IP3 receptor",
			"children":[
			{
				"name":"1277082 inositol 1,4,5-trisphosphate receptor isoform X1\tK04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1"
			}
			]
		}
		]
	},
	{
		"name":"Voltage-gated cation channels",
		"children":[
		{
			"name":"Sodium channel, voltage-gated (Nav)",
			"children":[
			{
				"name":"1278521 sodium channel protein para isoform X1\tK04834 SCN2A; voltage-gated sodium channel type II alpha"
			}
			]
		},
		{
			"name":"Calcium channel, voltage-gated (Cav)",
			"children":[
			{
				"name":"3292158 muscle calcium channel subunit alpha-1 isoform X1\tK04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D"
			},
			{
				"name":"4578503 muscle calcium channel subunit alpha-1 isoform X1\tK04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D"
			},
			{
				"name":"1273457 voltage-dependent T-type calcium channel subunit alpha-1G isoform X1\tK04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G"
			},
			{
				"name":"1276178 voltage-dependent calcium channel subunit alpha-2\/delta-3 isoform X1\tK04860 CACNA2D3; voltage-dependent calcium channel alpha-2\/delta-3"
			},
			{
				"name":"1278942 voltage-dependent calcium channel subunit alpha-2\/delta-3\tK04861 CACNA2D4; voltage-dependent calcium channel alpha-2\/delta-4"
			},
			{
				"name":"1277923 voltage-dependent L-type calcium channel subunit beta-1 isoform X1\tK04863 CACNB2; voltage-dependent calcium channel beta-2"
			},
			{
				"name":"1280001 VWFA and cache domain-containing protein CG16868\tK28855 CACHD1; VWFA and cache domain-containing protein 1"
			}
			]
		},
		{
			"name":"Calcium channel, sperm-associated (CatSper)"
		},
		{
			"name":"Calcium channel, two-pore (TPC)"
		},
		{
			"name":"Potassium channel, voltage-gated (Kv)",
			"children":[
			{
				"name":"1272004 potassium voltage-gated channel protein Shaker isoform X2\tK04874 KCNA1; potassium voltage-gated channel Shaker-related subfamily A member 1"
			},
			{
				"name":"1279500 uncharacterized protein LOC1279500 isoform X1\tK04883 KCNAB2; potassium voltage-gated channel Shaker-related subfamily A, beta member 2"
			},
			{
				"name":"1276592 potassium voltage-gated channel protein Shab isoform X1\tK04885 KCNB1; potassium voltage-gated channel Shab-related subfamily B member 1"
			},
			{
				"name":"1277770 potassium voltage-gated channel protein Shaw isoform X1\tK04887 KCNC1; potassium voltage-gated channel Shaw-related subfamily C member 1"
			},
			{
				"name":"1277771 potassium voltage-gated channel protein Shaw isoform X1\tK04887 KCNC1; potassium voltage-gated channel Shaw-related subfamily C member 1"
			},
			{
				"name":"1270054 potassium voltage-gated channel protein Shal isoform X3\tK04892 KCND2; potassium voltage-gated channel Shal-related subfamily D member 2"
			},
			{
				"name":"1273247 potassium voltage-gated channel protein eag isoform X1\tK04908 KCNH5; potassium voltage-gated channel Eag-related subfamily H member 5"
			},
			{
				"name":"1274964 potassium voltage-gated channel subfamily H member 8 isoform X1\tK04911 KCNH8; potassium voltage-gated channel Eag-related subfamily H member 8"
			},
			{
				"name":"1270812 potassium voltage-gated channel subfamily KQT member 4 isoform X1\tK04926 KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1"
			},
			{
				"name":"4576494 uncharacterized protein LOC4576494 isoform X1\tK04930 KCNQ5; potassium voltage-gated channel KQT-like subfamily member 5"
			}
			]
		},
		{
			"name":"Potassium channel, calcium- and sodium-activated (KCa\/KNa)",
			"children":[
			{
				"name":"1274388 calcium-activated potassium channel slowpoke isoform X1\tK04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1"
			},
			{
				"name":"1275242 small conductance calcium-activated potassium channel protein isoform X8\tK04944 KCNN3; potassium intermediate\/small conductance calcium-activated channel subfamily N member 3"
			},
			{
				"name":"5667033 potassium channel subfamily T member 2 isoform X1\tK04946 KCNT1; potassium channel subfamily T member 1"
			}
			]
		},
		{
			"name":"Potassium channel, two-pore domain (K2P)",
			"children":[
			{
				"name":"1273494 potassium channel subfamily K member 9\tK04919 KCNK9; potassium channel subfamily K member 9"
			},
			{
				"name":"1280744 two pore potassium channel protein sup-9\tK04919 KCNK9; potassium channel subfamily K member 9"
			},
			{
				"name":"11176095 potassium channel subfamily K member 18\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"1275696 TWiK family of potassium channels protein 7\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"1278508 TWiK family of potassium channels protein 7\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"1278511 potassium channel subfamily K member 18\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"1278858 uncharacterized protein LOC1278858 isoform X1\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			},
			{
				"name":"4576067 TWiK family of potassium channels protein 18\tK05323 KCNKN; potassium channel subfamily K, invertebrate"
			}
			]
		},
		{
			"name":"Potassium channel, inwardly-rectifying (Kir)",
			"children":[
			{
				"name":"1281895 G protein-activated inward rectifier potassium channel 3 isoform X1\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			},
			{
				"name":"1281896 G protein-activated inward rectifier potassium channel 3 isoform X1\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			},
			{
				"name":"1281897 G protein-activated inward rectifier potassium channel 3 isoform X5\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			},
			{
				"name":"133393836 ATP-sensitive inward rectifier potassium channel 11-like isoform X1\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			},
			{
				"name":"3290452 G protein-activated inward rectifier potassium channel 3\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			},
			{
				"name":"3291594 G protein-activated inward rectifier potassium channel 4\tK05330 KCNJN; potassium inwardly-rectifying channel subfamily J, other"
			}
			]
		},
		{
			"name":"Transient receptor potential channel (TRP)",
			"children":[
			{
				"name":"11175956 transient receptor potential cation channel protein painless\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"1271895 transient receptor potential channel pyrexia\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"1272164 transient receptor potential channel pyrexia\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"1275095 transient receptor potential cation channel subfamily A member 1 isoform X1\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"1279693 transient receptor potential channel pyrexia\tK04984 TRPA1; transient receptor potential cation channel subfamily A member 1"
			},
			{
				"name":"1271910 transient receptor potential protein\tK04967 TRPC4; transient receptor potential cation channel subfamily C member 4"
			},
			{
				"name":"1277541 transient receptor potential-gamma protein\tK04967 TRPC4; transient receptor potential cation channel subfamily C member 4"
			},
			{
				"name":"1269213 transient-receptor-potential-like protein\tK13803 TRPL; transient-receptor-potential-like protein"
			},
			{
				"name":"1280447 transient receptor potential cation channel subfamily V member 5\tK04974 TRPV5; transient receptor potential cation channel subfamily V member 5"
			},
			{
				"name":"1271831 uncharacterized protein LOC1271831\tK04975 TRPV6; transient receptor potential cation channel subfamily V member 6"
			},
			{
				"name":"1270239 transient receptor potential cation channel trpm isoform X9\tK04978 TRPM3; transient receptor potential cation channel subfamily M member 3"
			},
			{
				"name":"5667003 mucolipin-3\tK04994 MCOLN3; mucolipin 3"
			}
			]
		},
		{
			"name":"Cyclic nucleotide-gated channel (CNG)",
			"children":[
			{
				"name":"1280008 cyclic nucleotide-gated cation channel subunit A isoform X1\tK04950 CNGA3; cyclic nucleotide gated channel alpha 3"
			},
			{
				"name":"4576205 cyclic nucleotide-gated olfactory channel isoform X1\tK04950 CNGA3; cyclic nucleotide gated channel alpha 3"
			},
			{
				"name":"3291342 cyclic nucleotide-gated cation channel beta-3\tK04952 CNGB1; cyclic nucleotide gated channel beta 1"
			}
			]
		},
		{
			"name":"Cyclic nucleotide-gated channel (HCN)",
			"children":[
			{
				"name":"1269408 uncharacterized protein LOC1269408 isoform X1\tK04955 HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2"
			},
			{
				"name":"5667072 potassium\/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2\tK04955 HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2"
			}
			]
		},
		{
			"name":"Sodium leak channel, non-selective",
			"children":[
			{
				"name":"1278744 sodium leak channel NALCN isoform X1\tK21863 NALCN; sodium leak channel non-selective protein"
			},
			{
				"name":"1279690 protein unc-79 homolog isoform X1\tK24014 UNC79; protein unc-79"
			},
			{
				"name":"1281602 protein unc-80 homolog isoform X1\tK24015 UNC80; protein unc-80"
			}
			]
		},
		{
			"name":"Proton channel, voltage-gated (Hv)"
		},
		{
			"name":"Ryanodine receptor",
			"children":[
			{
				"name":"1278919 ryanodine receptor isoform X3\tK04962 RYR2; ryanodine receptor 2"
			}
			]
		}
		]
	},
	{
		"name":"Chloride channels",
		"children":[
		{
			"name":"Chloride channel (CLC)",
			"children":[
			{
				"name":"1273077 chloride channel protein 2 isoform X1\tK05011 CLCN2; chloride channel 2"
			},
			{
				"name":"1276446 H(+)\/Cl(-) exchange transporter 5 isoform X2\tK05012 CLCN3_4_5; chloride channel 3\/4\/5"
			},
			{
				"name":"1269729 H(+)\/Cl(-) exchange transporter 7 isoform X1\tK05016 CLCN7; chloride channel 7"
			},
			{
				"name":"1277425 osteopetrosis-associated transmembrane protein 1\tK23863 OSTM1; osteopetrosis-associated transmembrane protein 1 (chloride channel 7 beta subunit)"
			}
			]
		},
		{
			"name":"Chloride channel, intracellular (CLIC)",
			"children":[
			{
				"name":"1270427 chloride intracellular channel Clic isoform X2\tK05022 CLIC2; chloride intracellular channel protein 2"
			}
			]
		},
		{
			"name":"Chloride channel, calcium-activated (CaCC)",
			"children":[
			{
				"name":"1272176 anoctamin-2 isoform X5\tK19496 ANO1; anoctamin-1"
			},
			{
				"name":"1272564 anoctamin-4 isoform X1\tK19499 ANO4; anoctamin-4"
			},
			{
				"name":"1279420 anoctamin-8 isoform X1\tK19502 ANO8; anoctamin-8"
			},
			{
				"name":"1279184 anoctamin-10 isoform X1\tK19327 ANO10; anoctamin-10"
			},
			{
				"name":"3290954 calcium-activated chloride channel regulator 1\tK05030 CLCA3_4; calcium-activated chloride channel regulator 3\/4"
			}
			]
		},
		{
			"name":"Chloride channel, volume-regulated (VRAC)"
		},
		{
			"name":"Maxi chloride channel (VDAC)",
			"children":[
			{
				"name":"1279252 voltage-dependent anion-selective channel\tK15040 VDAC2; voltage-dependent anion channel protein 2"
			}
			]
		}
		]
	},
	{
		"name":"Other channels",
		"children":[
		{
			"name":"Calcium channel, calcium release-activated (Orai)",
			"children":[
			{
				"name":"1274753 calcium release-activated calcium channel protein 1 isoform X1\tK16056 ORAI1; calcium release-activated calcium channel protein 1"
			}
			]
		},
		{
			"name":"Mechanosensitive channel (Piezo)"
		}
		]
	}
	]
}
