{
	"name":"ago04131",
	"children":[
	{
		"name":"Exocytosis",
		"children":[
		{
			"name":"Calcium ion-dependent exocytosis",
			"children":[
			{
				"name":"Synaptotagmins"
			},
			{
				"name":"Septins",
				"children":[
				{
					"name":"AGOS_AFR111C AFR111Cp\tK16944 SEPT7; septin 7"
				}
				]
			},
			{
				"name":"DOC-2 proteins"
			},
			{
				"name":"Acrosomal exocytosis proteins",
				"children":[
				{
					"name":"AGOS_AFR335C AFR335Cp\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_AFR377C AFR377Cp\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipases",
				"children":[
				{
					"name":"AGOS_ACR024W ACR024Wp\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				},
				{
					"name":"AGOS_AFR071W AFR071Wp\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				}
				]
			},
			{
				"name":"Kinases and associated proteins",
				"children":[
				{
					"name":"AGOS_AGL096W AGL096Wp\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"AGOS_ABR014W ABR014Wp\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_ABR096C ABR096Cp\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"AGOS_AGR058W AGR058Wp\tK19852 KIN1_2; serine\/threonine protein kinase KIN1\/2 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_ACL163W ACL163Wp\tK19932 NCS1; neuronal calcium sensor"
				}
				]
			}
			]
		},
		{
			"name":"Small GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"AGOS_AGL021W AGL021Wp\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"AGOS_ADL337W ADL337Wp\tK02183 CALM; calmodulin"
				},
				{
					"name":"AGOS_AEL280W AEL280Wp\tK02183 CALM; calmodulin"
				},
				{
					"name":"AGOS_AFR670W AFR670Wp\tK19940 SEC2; Rab guanine nucleotide exchange factor SEC2"
				},
				{
					"name":"AGOS_AGL162C AGL162Cp\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"AGOS_ACR190C ACR190Cp\tK08518 STXBP5; syntaxin-binding protein 5"
				},
				{
					"name":"AGOS_AEL201W AEL201Wp\tK19953 GRTP1; TBC1 domain family member 6"
				},
				{
					"name":"AGOS_AAR091W AAR091Wp\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"AGOS_AFR453W AFR453Wp\tK13342 PEX5; peroxin-5"
				},
				{
					"name":"AGOS_ADR413C ADR413Cp\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"AGOS_ACR042C ACR042Cp\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"AGOS_AEL268W AEL268Wp\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"AGOS_AEL063W AEL063Wp\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"Rho GTPases",
				"children":[
				{
					"name":"AGOS_AGL093W AGL093Wp\tK04393 CDC42; cell division control protein 42"
				}
				]
			},
			{
				"name":"Other small GTPases and associated proteins"
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Exocyst complex",
				"children":[
				{
					"name":"AGOS_ADR012C ADR012Cp\tK19983 EXOC1; exocyst complex component 1"
				},
				{
					"name":"AGOS_AGL158C AGL158Cp\tK17637 EXOC2; exocyst complex component 2"
				},
				{
					"name":"AGOS_ACL047W ACL047Wp\tK06110 EXOC3; exocyst complex component 3"
				},
				{
					"name":"AGOS_ADL317C ADL317Cp\tK06111 EXOC4; exocyst complex component 4"
				},
				{
					"name":"AGOS_AGL130C AGL130Cp\tK19984 EXOC5; exocyst complex component 5"
				},
				{
					"name":"AGOS_AFR251C AFR251Cp\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"AGOS_AFR100W AFR100Wp\tK07195 EXOC7; exocyst complex component 7"
				},
				{
					"name":"AGOS_ADL321W ADL321Wp\tK19986 EXOC8; exocyst complex component 8"
				}
				]
			},
			{
				"name":"Exocyst complex assembly proteins",
				"children":[
				{
					"name":"AGOS_AER253W AER253Wp\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
				},
				{
					"name":"AGOS_AER424C AER424Cp\tK17945 TPM1_2; tropomyosin, fungi type"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Exomer complex",
				"children":[
				{
					"name":"AGOS_AGL051C AGL051Cp\tK19877 CHS5; chitin biosynthesis protein CHS5"
				},
				{
					"name":"AGOS_AFR088W AFR088Wp\tK19880 CHS6; Chs5-Arf1p-binding protein CHS6\/BCH2"
				},
				{
					"name":"AGOS_AFR528W AFR528Wp\tK19881 BUD7; Chs5-Arf1p-binding protein BUD7\/BCH1"
				}
				]
			},
			{
				"name":"ER-PM contacts associated proteins",
				"children":[
				{
					"name":"AGOS_AGR088W AGR088Wp\tK24964 BLTP1; Bridge-like lipid transfer protein family member 1"
				},
				{
					"name":"AGOS_AER148W AER148Wp\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"AGOS_AER411W AER411Wp\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"AGOS_AGL282W AGL282Wp\tK29085 SCS2_22; vesicle-associated membrane protein-associated protein"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_ABR115C ABR115Cp\tK19992 MSO1; protein MSO1"
				},
				{
					"name":"AGOS_AGR365C AGR365Cp\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"AGOS_ACR247W ACR247Wp\tK19996 SFH5; phosphatidylinositol transfer protein SFH5"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"SNARE",
		"children":[
		{
			"name":"Syntaxin (Qa)",
			"children":[
			{
				"name":"Stx-PM",
				"children":[
				{
					"name":"AGOS_AFL139W AFL139Wp\tK08486 STX1B_2_3; syntaxin 1B\/2\/3"
				}
				]
			},
			{
				"name":"Stx-Endo",
				"children":[
				{
					"name":"AGOS_AFL232W AFL232Wp\tK21155 VAM3; syntaxin VAM3"
				}
				]
			},
			{
				"name":"Stx-TGN \/ EE",
				"children":[
				{
					"name":"AGOS_AEL026C AEL026Cp\tK08489 STX16; syntaxin 16"
				}
				]
			},
			{
				"name":"Stx-cisGolgi",
				"children":[
				{
					"name":"AGOS_AFR210C AFR210Cp\tK08490 STX5; syntaxin 5"
				}
				]
			},
			{
				"name":"Stx-sER"
			},
			{
				"name":"Stx-rER",
				"children":[
				{
					"name":"AGOS_ADR220W ADR220Wp\tK08492 STX18; syntaxin 18"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[N] (Qb)",
			"children":[
			{
				"name":"Vti1",
				"children":[
				{
					"name":"AGOS_AFL168W AFL168Wp\tK08493 VTI1; vesicle transport through interaction with t-SNAREs 1"
				}
				]
			},
			{
				"name":"NPSN"
			},
			{
				"name":"Gos1 (Gos28)",
				"children":[
				{
					"name":"AGOS_ACL067C ACL067Cp\tK08495 GOSR1; golgi SNAP receptor complex member 1"
				}
				]
			},
			{
				"name":"Bos1 \/ Membrin",
				"children":[
				{
					"name":"AGOS_ABR239C ABR239Cp\tK08496 GOSR2; golgi SNAP receptor complex member 2"
				}
				]
			},
			{
				"name":"Sec20",
				"children":[
				{
					"name":"AGOS_AFR344C AFR344Cp\tK08497 SEC20; protein transport protein SEC20"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[C] (Qc)",
			"children":[
			{
				"name":"STX6",
				"children":[
				{
					"name":"AGOS_AFR375W AFR375Wp\tK08499 TLG1; member of the syntaxin family of t-SNAREs"
				}
				]
			},
			{
				"name":"STX8",
				"children":[
				{
					"name":"AGOS_ACR275W ACR275Wp\tK08501 STX8; syntaxin 8"
				},
				{
					"name":"AGOS_AER438C AER438Cp\tK08502 VAM7; regulator of vacuolar morphogenesis"
				}
				]
			},
			{
				"name":"STX10"
			},
			{
				"name":"Bet1",
				"children":[
				{
					"name":"AGOS_ADL007C ADL007Cp\tK08504 BET1; blocked early in transport 1"
				}
				]
			},
			{
				"name":"Sft1",
				"children":[
				{
					"name":"AGOS_ABR006W ABR006Wp\tK08505 SFT1; protein transport protein SFT1"
				}
				]
			},
			{
				"name":"Syp7"
			},
			{
				"name":"Use1",
				"children":[
				{
					"name":"AGOS_AFL043C AFL043Cp\tK08507 USE1; unconventional SNARE in the endoplasmic reticulum protein 1"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25 (Qb,c)",
			"children":[
			{
				"name":"SNAP-23"
			},
			{
				"name":"SNAP-25",
				"children":[
				{
					"name":"AGOS_AFR469W AFR469Wp\tK19950 SEC9; protein transport protein SEC9"
				}
				]
			},
			{
				"name":"SNAP-29"
			},
			{
				"name":"SNAP-47"
			}
			]
		},
		{
			"name":"VAMP, Ykt6, Sec22 (R)",
			"children":[
			{
				"name":"VAMP",
				"children":[
				{
					"name":"AGOS_ADR355C ADR355Cp\tK08513 VAMP4; vesicle-associated membrane protein 4"
				},
				{
					"name":"AGOS_AGR054C AGR054Cp\tK08564 NYV1; vacuolar v-SNARE NYV1"
				}
				]
			},
			{
				"name":"Ykt6",
				"children":[
				{
					"name":"AGOS_AER109W AER109Wp\tK08516 YKT6; synaptobrevin homolog YKT6"
				}
				]
			},
			{
				"name":"Sec22",
				"children":[
				{
					"name":"AGOS_AGR267W AGR267Wp\tK08517 SEC22; vesicle transport protein SEC22"
				}
				]
			},
			{
				"name":"Tomosyn",
				"children":[
				{
					"name":"AGOS_ACR190C ACR190Cp\tK08518 STXBP5; syntaxin-binding protein 5"
				}
				]
			},
			{
				"name":"Putative SNAREs"
			}
			]
		},
		{
			"name":"SNARE associated proteins",
			"children":[
			{
				"name":"Syntaxin-binding proteins",
				"children":[
				{
					"name":"AGOS_AGL162C AGL162Cp\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"AGOS_AGL120W AGL120Wp\tK19998 SCFD1; sec1 family domain-containing protein 1"
				}
				]
			},
			{
				"name":"Palmitoyltransferases",
				"children":[
				{
					"name":"AGOS_ADL197C ADL197Cp\tK20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2\/15\/20 [EC:2.3.1.225]"
				},
				{
					"name":"AGOS_AGR065W AGR065Wp\tK20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]"
				},
				{
					"name":"AGOS_AER388C AER388Cp\tK20032 ZDHHC13_17; palmitoyltransferase ZDHHC13\/17 [EC:2.3.1.225]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_AER169C AER169Cp\tK06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]"
				},
				{
					"name":"AGOS_ABR155C ABR155Cp\tK15296 NAPA; alpha-soluble NSF attachment protein"
				},
				{
					"name":"AGOS_ACR074W ACR074Wp\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"AGOS_ADL293W ADL293Wp\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"AGOS_ADR192C ADR192Cp\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"AGOS_ACL165C ACL165Cp\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"AGOS_AFR158W AFR158Wp\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"AGOS_ABR211C ABR211Cp\tK14012 NSFL1C; UBX domain-containing protein 1"
				},
				{
					"name":"AGOS_ADR394W ADR394Wp\tK27407 VTS1; RNA-binding protein VTS1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endocytosis",
		"children":[
		{
			"name":"Clathrin-mediated endocytosis",
			"children":[
			{
				"name":"Clathrin",
				"children":[
				{
					"name":"AGOS_AER359W AER359Wp\tK04646 CLTC; clathrin heavy chain"
				}
				]
			},
			{
				"name":"Dynamin",
				"children":[
				{
					"name":"AGOS_AAL174C AAL174Cp\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			},
			{
				"name":"AP-2 complex",
				"children":[
				{
					"name":"AGOS_ADL302W ADL302Wp\tK11824 AP2A; AP-2 complex subunit alpha"
				},
				{
					"name":"AGOS_ADR342C ADR342Cp\tK11825 AP2B1; AP-2 complex subunit beta-1"
				},
				{
					"name":"AGOS_ADR315W ADR315Wp\tK11826 AP2M1; AP-2 complex subunit mu-1"
				},
				{
					"name":"AGOS_AFR370C AFR370Cp\tK11827 AP2S1; AP-2 complex subunit sigma-1"
				}
				]
			},
			{
				"name":"Other core components",
				"children":[
				{
					"name":"AGOS_AEL147W AEL147Wp\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"AGOS_ACL157C ACL157Cp\tK12471 EPN; epsin"
				},
				{
					"name":"AGOS_AER155C AER155Cp\tK12471 EPN; epsin"
				},
				{
					"name":"AGOS_AGR046C AGR046Cp\tK12471 EPN; epsin"
				},
				{
					"name":"AGOS_ABR149W ABR149Wp\tK12472 EPS15; epidermal growth factor receptor substrate 15"
				},
				{
					"name":"AGOS_AEL209W AEL209Wp\tK20044 PICALM; phosphatidylinositol-binding clathrin assembly protein"
				},
				{
					"name":"AGOS_AER140C AER140Cp\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"AGOS_AFR140C AFR140Cp\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"AGOS_AGR170C AGR170Cp\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"AGOS_ADR018C ADR018Cp\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"AGOS_AER416C AER416Cp\tK20048 END3; actin cytoskeleton-regulatory complex protein END3"
				},
				{
					"name":"AGOS_ABL174C ABL174Cp\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"AGOS_AER187W AER187Wp\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"AGOS_AFR114W AFR114Wp\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				}
				]
			},
			{
				"name":"Low-density lipoprotein receptor (LDLR) family proteins"
			},
			{
				"name":"LDLR adaptor proteins",
				"children":[
				{
					"name":"AGOS_AGL096W AGL096Wp\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				}
				]
			},
			{
				"name":"GPCR adaptor proteins",
				"children":[
				{
					"name":"AGOS_ACR291C ACR291Cp\tK20059 LDB19; arrestin-related trafficking adapter 1"
				},
				{
					"name":"AGOS_ADR065W ADR065Wp\tK20060 ECM21; arrestin-related trafficking adapter 2\/8"
				},
				{
					"name":"AGOS_AFR101C AFR101Cp\tK20061 ALY1_2; arrestin-related trafficking adapter 3\/6"
				},
				{
					"name":"AGOS_ADR172C ADR172Cp\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"AGOS_AFR581C AFR581Cp\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"AGOS_AFR108W AFR108Wp\tK20063 RIM8; arrestin-related trafficking adapter 9"
				}
				]
			},
			{
				"name":"Receptor tyrosine kinase (RTK) adaptor proteins"
			},
			{
				"name":"Inositol 5-phosphatases",
				"children":[
				{
					"name":"AGOS_ADL002C ADL002Cp\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				},
				{
					"name":"AGOS_AFL228W AFL228Wp\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"AGOS_ADL217W ADL217Wp\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_AFL068C AFL068Cp\tK17541 SCYL2; SCY1-like protein 2"
				}
				]
			},
			{
				"name":"Ubiquitin E3 ligases",
				"children":[
				{
					"name":"AGOS_ADL055C ADL055Cp\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Lipid raft mediated endocytosis",
			"children":[
			{
				"name":"Caveolin-mediated endocytosis",
				"children":[
				{
					"name":"AGOS_AAL174C AAL174Cp\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				},
				{
					"name":"AGOS_ACR191C ACR191Cp\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
				}
				]
			},
			{
				"name":"Flotillin-dependent endocytosis"
			},
			{
				"name":"GRAF1-dependent endocytosis",
				"children":[
				{
					"name":"AGOS_AGL093W AGL093Wp\tK04393 CDC42; cell division control protein 42"
				},
				{
					"name":"AGOS_ADR094W ADR094Wp\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				}
				]
			},
			{
				"name":"Arf6-dependent endocytosis",
				"children":[
				{
					"name":"AGOS_ACL078W ACL078Wp\tK07941 ARF6; ADP-ribosylation factor 6"
				}
				]
			},
			{
				"name":"RhoA-dependent endocytosis",
				"children":[
				{
					"name":"AGOS_ABR183W ABR183Wp\tK04513 RHOA; Ras homolog gene family, member A"
				},
				{
					"name":"AGOS_AAL174C AAL174Cp\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			}
			]
		},
		{
			"name":"Phagocytosis",
			"children":[
			{
				"name":"Fc receptors"
			},
			{
				"name":"Integrins (complement receptors)"
			},
			{
				"name":"Opsonins"
			},
			{
				"name":"Toll-like receptors"
			},
			{
				"name":"C-lectin receptors"
			},
			{
				"name":"Scavenger receptors"
			},
			{
				"name":"Coronins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_AEL306C AEL306Cp\tK10356 MYO1; myosin I"
				}
				]
			}
			]
		},
		{
			"name":"Macropinocytosis",
			"children":[
			{
				"name":"Ras GTPases",
				"children":[
				{
					"name":"AGOS_ADL262W ADL262Wp\tK07827 KRAS; GTPase KRas"
				},
				{
					"name":"AGOS_AGL093W AGL093Wp\tK04393 CDC42; cell division control protein 42"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"AGOS_AGL113C AGL113Cp\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"AGOS_AER188C AER188Cp\tK00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]"
				},
				{
					"name":"AGOS_ABR014W ABR014Wp\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipase C",
				"children":[
				{
					"name":"AGOS_ACR024W ACR024Wp\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				}
				]
			},
			{
				"name":"Sorting nexins",
				"children":[
				{
					"name":"AGOS_ADR211W ADR211Wp\tK17917 SNX1_2; sorting nexin-1\/2"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Bin\/Amphiphysin\/Rvs (BAR) family proteins",
			"children":[
			{
				"name":"N-BAR proteins",
				"children":[
				{
					"name":"AGOS_AER140C AER140Cp\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"AGOS_AFR140C AFR140Cp\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"AGOS_AER193W AER193Wp\tK20120 BIN3; bridging integrator 3"
				}
				]
			},
			{
				"name":"F-BAR proteins",
				"children":[
				{
					"name":"AGOS_ACR266W ACR266Wp\tK20121 FNBP1; formin-binding protein 1"
				},
				{
					"name":"AGOS_AEL147W AEL147Wp\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"AGOS_AFR616W AFR616Wp\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				}
				]
			},
			{
				"name":"I-BAR proteins"
			}
			]
		},
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"AGOS_AAL176C AAL176Cp\tK07888 RAB5B; Ras-related protein Rab-5B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"AGOS_ADL349W ADL349Wp\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"AGOS_AGR365C AGR365Cp\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"AGOS_AGL113C AGL113Cp\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"AGOS_ADL316C ADL316Cp\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_AFL053W AFL053Wp\tK12479 VPS45; vacuolar protein sorting-associated protein 45"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"AGOS_ADR094W ADR094Wp\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"AGOS_ACL078W ACL078Wp\tK07941 ARF6; ADP-ribosylation factor 6"
				}
				]
			},
			{
				"name":"Arf associated proteins",
				"children":[
				{
					"name":"AGOS_ACL055W ACL055Wp\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"AGOS_ADL084W ADL084Wp\tK12486 SMAP; stromal membrane-associated protein"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Fucosyltransferase"
			},
			{
				"name":"EFR3-PI4KIII alpha complex and associated proteins",
				"children":[
				{
					"name":"AGOS_ADL033W ADL033Wp\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"AGOS_AER343C AER343Cp\tK21842 EFR3; protein EFR3"
				},
				{
					"name":"AGOS_ACL113C ACL113Cp\tK21845 YPP1; cargo-transport protein YPP1"
				}
				]
			},
			{
				"name":"Insulin-like growth factor-binding proteins"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Lysosome transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"AGOS_AAL176C AAL176Cp\tK07888 RAB5B; Ras-related protein Rab-5B"
				},
				{
					"name":"AGOS_ACR003C ACR003Cp\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"FTS\/Hook\/FHIP (FHF) complex"
			},
			{
				"name":"FERRY complex"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"AGOS_AGL113C AGL113Cp\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"AGOS_AAR012C AAR012Cp\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"AGOS_ACR057C ACR057Cp\tK18469 TBC1D5; TBC1 domain family member 5"
				},
				{
					"name":"AGOS_ABL179C ABL179Cp\tK20168 TBC1D15; TBC1 domain family member 15"
				},
				{
					"name":"AGOS_ADR413C ADR413Cp\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"AGOS_ACR042C ACR042Cp\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"AGOS_AEL268W AEL268Wp\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"AGOS_ACL165C ACL165Cp\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"AGOS_AEL232C AEL232Cp\tK07955 ARL8; ADP-ribosylation factor-like protein 8"
				}
				]
			},
			{
				"name":"BLOC-one-related complex (BORC)"
			},
			{
				"name":"N-acetyl transferase complex C (NatC)",
				"children":[
				{
					"name":"AGOS_ADL308C ADL308Cp\tK00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]"
				},
				{
					"name":"AGOS_AAR133W AAR133Wp\tK20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit"
				},
				{
					"name":"AGOS_AEL047C AEL047Cp\tK20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit"
				}
				]
			},
			{
				"name":"Other Arf associated proteins"
			}
			]
		},
		{
			"name":"Endosomal sorting complexes required for transport (ESCRT)",
			"children":[
			{
				"name":"ESCRT-0 complex",
				"children":[
				{
					"name":"AGOS_AFL176C AFL176Cp\tK12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate"
				},
				{
					"name":"AGOS_ABR008C ABR008Cp\tK04705 STAM; signal transducing adaptor molecule"
				}
				]
			},
			{
				"name":"ESCRT-I complex",
				"children":[
				{
					"name":"AGOS_AAL006C AAL006Cp\tK12183 TSG101; ESCRT-I complex subunit TSG101"
				},
				{
					"name":"AGOS_ADR043W ADR043Wp\tK12184 VPS28; ESCRT-I complex subunit VPS28"
				},
				{
					"name":"AGOS_ACL128C ACL128Cp\tK12187 MVB12; ESCRT-I complex subunit MVB12"
				}
				]
			},
			{
				"name":"ESCRT-II complex",
				"children":[
				{
					"name":"AGOS_AGL002C AGL002Cp\tK12188 SNF8; ESCRT-II complex subunit VPS22"
				},
				{
					"name":"AGOS_AGL318W AGL318Wp\tK12189 VPS25; ESCRT-II complex subunit VPS25"
				},
				{
					"name":"AGOS_AER092W AER092Wp\tK12190 VPS36; ESCRT-II complex subunit VPS36"
				}
				]
			},
			{
				"name":"ESCRT-III complex",
				"children":[
				{
					"name":"AGOS_AFR068C AFR068Cp\tK12197 CHMP1; charged multivesicular body protein 1"
				},
				{
					"name":"AGOS_ABR002C ABR002Cp\tK12191 CHMP2A; charged multivesicular body protein 2A"
				},
				{
					"name":"AGOS_ABR049C ABR049Cp\tK12193 VPS24; charged multivesicular body protein 3"
				},
				{
					"name":"AGOS_AFR209W AFR209Wp\tK12194 CHMP4A_B; charged multivesicular body protein 4A\/B"
				},
				{
					"name":"AGOS_ADR116C ADR116Cp\tK12198 CHMP5; charged multivesicular body protein 5"
				},
				{
					"name":"AGOS_AGR014W AGR014Wp\tK12195 CHMP6; charged multivesicular body protein 6"
				},
				{
					"name":"AGOS_AEL183C AEL183Cp\tK15053 CHMP7; charged multivesicular body protein 7"
				},
				{
					"name":"AGOS_AEL265W AEL265Wp\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				}
				]
			},
			{
				"name":"ESCRT associated proteins",
				"children":[
				{
					"name":"AGOS_AFR691W AFR691Wp\tK12199 VTA1; vacuolar protein sorting-associated protein VTA1"
				},
				{
					"name":"AGOS_AER342C AER342Cp\tK12200 PDCD6IP; programmed cell death 6-interacting protein"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"CORVET complex",
				"children":[
				{
					"name":"AGOS_AFR341C AFR341Cp\tK20177 VPS3; vacuolar protein sorting-associated protein 3"
				},
				{
					"name":"AGOS_AFR002C AFR002Cp\tK20178 VPS8; vacuolar protein sorting-associated protein 8"
				},
				{
					"name":"AGOS_ABL012C ABL012Cp\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"AGOS_AGL252W AGL252Wp\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"AGOS_AGL156W AGL156Wp\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"AGOS_AER064C AER064Cp\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				}
				]
			},
			{
				"name":"Hops complex",
				"children":[
				{
					"name":"AGOS_ABL012C ABL012Cp\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"AGOS_AGL252W AGL252Wp\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"AGOS_AGL156W AGL156Wp\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"AGOS_AER064C AER064Cp\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				},
				{
					"name":"AGOS_AER080W AER080Wp\tK20183 VPS39; Vam6\/Vps39-like protein vacuolar protein sorting-associated protein 39"
				},
				{
					"name":"AGOS_AGR149W AGR149Wp\tK20184 VPS41; vacuolar protein sorting-associated protein 41"
				}
				]
			}
			]
		},
		{
			"name":"Acidification regulators",
			"children":[
			{
				"name":"Rabconnectin-3 complex",
				"children":[
				{
					"name":"AGOS_AEL063W AEL063Wp\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"RAVE complex",
				"children":[
				{
					"name":"AGOS_AEL063W AEL063Wp\tK24155 DMXL; rabconnectin-3a"
				},
				{
					"name":"AGOS_AGL104C AGL104Cp\tK25485 RAV2; regulator of V-ATPase in vacuolar membrane protein 2"
				},
				{
					"name":"AGOS_ADR295C ADR295Cp\tK03094 SKP1; S-phase kinase-associated protein 1"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"AGOS_AFL076W AFL076Wp\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"AGOS_ADR335C ADR335Cp\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"AGOS_AGL061W AGL061Wp\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"AGOS_AAL143W AAL143Wp\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"BLOC-1 complex"
			},
			{
				"name":"BLOC-1 complex (yeast)",
				"children":[
				{
					"name":"AGOS_ABR062W ABR062Wp\tK22238 BLI1; biogenesis of lysosome-related organelles complex 1 subunit BLI1"
				},
				{
					"name":"AGOS_AER079C AER079Cp\tK22239 BLS1; biogenesis of lysosome-related organelles complex 1 subunit BLS1"
				},
				{
					"name":"AGOS_AER242C AER242Cp\tK22240 CNL1; biogenesis of lysosome-related organelles complex 1 subunit CNL1"
				},
				{
					"name":"AGOS_AER412W AER412Wp\tK22241 SNN1; biogenesis of lysosome-related organelles complex 1 subunit SNN1"
				},
				{
					"name":"AGOS_ADL005C ADL005Cp\tK22242 VAB2; biogenesis of lysosome-related organelles complex 1 subunit VAB2"
				},
				{
					"name":"AGOS_AFL077C AFL077Cp\tK22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1"
				}
				]
			},
			{
				"name":"BLOC-2 complex"
			},
			{
				"name":"BLOC-3 complex"
			},
			{
				"name":"Ferlins"
			},
			{
				"name":"Lysosomal membrane proteins",
				"children":[
				{
					"name":"AGOS_AFR567W AFR567Wp\tK13526 ATP13A2; cation-transporting P-type ATPase 13A2 [EC:7.2.2.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_AAR175C AAR175Cp\tK20195 MON1; vacuolar fusion protein MON1"
				},
				{
					"name":"AGOS_AAR040C AAR040Cp\tK21156 CCZ1; vacuolar fusion protein CCZ1, fungi type"
				},
				{
					"name":"AGOS_AFR007W AFR007Wp\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"AGOS_AFR351C AFR351Cp\tK28212 LEPROT; OB-RGRP\/VPS55 family protein"
				},
				{
					"name":"AGOS_ADL169W ADL169Wp\tK29023 VPS68; vacuolar protein sorting-associated protein 68"
				},
				{
					"name":"AGOS_ABL001W ABL001Wp\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"AGOS_AFR620W AFR620Wp\tK24781 BPH1; beige protein homolog 1"
				},
				{
					"name":"AGOS_ADL246W ADL246Wp\tK28440 VAC7; vacuolar segregation protein 7"
				},
				{
					"name":"AGOS_AFR122C AFR122Cp\tK28441 TAG1; protein TAG1"
				},
				{
					"name":"AGOS_ABL026W ABL026Wp\tK28544 SSH4; SSH4 family protein"
				},
				{
					"name":"AGOS_ADL279W ADL279Wp\tK28544 SSH4; SSH4 family protein"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein recycling",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"AGOS_AER434C AER434Cp\tK07905 RAB11B; Ras-related protein Rab-11B"
				}
				]
			},
			{
				"name":"Rab4 associated proteins",
				"children":[
				{
					"name":"AGOS_AGR365C AGR365Cp\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"AGOS_ACR074W ACR074Wp\tK17919 SNX4; sorting nexin-4"
				}
				]
			},
			{
				"name":"Rab11 associated proteins",
				"children":[
				{
					"name":"AGOS_ABL024W ABL024Wp\tK20241 WDR44; WD repeat-containing protein 44"
				},
				{
					"name":"AGOS_ACR199C ACR199Cp\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"AGOS_AFR251C AFR251Cp\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"AGOS_AFL161C AFL161Cp\tK20242 EVI5; ecotropic viral integration site 5 protein"
				},
				{
					"name":"AGOS_ACL165C ACL165Cp\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			},
			{
				"name":"Other Rab GTPase associated proteins",
				"children":[
				{
					"name":"AGOS_ADL349W ADL349Wp\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"AGOS_ACR226W ACR226Wp\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Glutamate receptor-interacting proteins (GRIPs)"
			},
			{
				"name":"GRIP associated proteins"
			},
			{
				"name":"EARP complex",
				"children":[
				{
					"name":"AGOS_ADR112W ADR112Wp\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"AGOS_ACR044C ACR044Cp\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				}
				]
			},
			{
				"name":"WASH complex",
				"children":[
				{
					"name":"AGOS_ABR007C ABR007Cp\tK10364 CAPZA; F-actin-capping protein subunit alpha"
				},
				{
					"name":"AGOS_ADL101C ADL101Cp\tK10365 CAPZB; F-actin-capping protein subunit beta"
				}
				]
			},
			{
				"name":"Retriever complex",
				"children":[
				{
					"name":"AGOS_AFR411C AFR411Cp\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				}
				]
			},
			{
				"name":"CCC complex"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_AGR088W AGR088Wp\tK24964 BLTP1; Bridge-like lipid transfer protein family member 1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Golgi transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"AGOS_ACR003C ACR003Cp\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"Retromer subcomplex",
				"children":[
				{
					"name":"AGOS_AEL107W AEL107Wp\tK18468 VPS35; vacuolar protein sorting-associated protein 35"
				},
				{
					"name":"AGOS_AFR411C AFR411Cp\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				},
				{
					"name":"AGOS_AEL178C AEL178Cp\tK18466 VPS26A_B; vacuolar protein sorting-associated protein 26A\/B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"AGOS_ACL165C ACL165Cp\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"AGOS_AAR091W AAR091Wp\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"AGOS_ABL071W ABL071Wp\tK20286 TMF1; TATA element modulatory factor"
				},
				{
					"name":"AGOS_AAL109W AAL109Wp\tK04648 DCTN1; dynactin 1"
				},
				{
					"name":"AGOS_ACL064C ACL064Cp\tK19525 VPS13A_C; vacuolar protein sorting-associated protein 13A\/C"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"AGOS_ADR094W ADR094Wp\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"AGOS_AGR221W AGR221Wp\tK07942 ARL1; ADP-ribosylation factor-like protein 1"
				},
				{
					"name":"AGOS_AGL261W AGL261Wp\tK07952 ARFRP1; ADP-ribosylation factor related protein 1"
				}
				]
			},
			{
				"name":"Arf GTPase associated proteins",
				"children":[
				{
					"name":"AGOS_ABL164C ABL164Cp\tK12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1"
				},
				{
					"name":"AGOS_AGL279C AGL279Cp\tK12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2\/3"
				},
				{
					"name":"AGOS_ACL055W ACL055Wp\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"AGOS_ADL084W ADL084Wp\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"AGOS_AFR725C AFR725Cp\tK12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein"
				},
				{
					"name":"AGOS_AGL147C AGL147Cp\tK18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein"
				},
				{
					"name":"AGOS_AEL061W AEL061Wp\tK18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Conserved oligomeric Golgi (COG) complex",
				"children":[
				{
					"name":"AGOS_AGR147W AGR147Wp\tK20290 COG3; conserved oligomeric Golgi complex subunit 3"
				},
				{
					"name":"AGOS_AEL328W AEL328Wp\tK20291 COG4; conserved oligomeric Golgi complex subunit 4"
				},
				{
					"name":"AGOS_ADL228C ADL228Cp\tK20293 COG6; conserved oligomeric Golgi complex subunit 6"
				},
				{
					"name":"AGOS_AER147W AER147Wp\tK20295 COG8; conserved oligomeric Golgi complex subunit 8"
				}
				]
			},
			{
				"name":"GARP complex",
				"children":[
				{
					"name":"AGOS_AFR102C AFR102Cp\tK20297 VPS51; vacuolar protein sorting-associated protein 51"
				},
				{
					"name":"AGOS_ADR112W ADR112Wp\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"AGOS_ACR044C ACR044Cp\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				},
				{
					"name":"AGOS_ABL093W ABL093Wp\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
				}
				]
			},
			{
				"name":"TRAPP complex II",
				"children":[
				{
					"name":"AGOS_AER154C AER154Cp\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"AGOS_AGR246W AGR246Wp\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"AGOS_AGR300W AGR300Wp\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"AGOS_AFR459W AFR459Wp\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"AGOS_AFR408C AFR408Cp\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"AGOS_ACR265C ACR265Cp\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				},
				{
					"name":"AGOS_AGR096C AGR096Cp\tK20305 TRAPPC8; trafficking protein particle complex subunit 8"
				},
				{
					"name":"AGOS_AAR118C AAR118Cp\tK20306 TRAPPC9; trafficking protein particle complex subunit 9"
				},
				{
					"name":"AGOS_AER352C AER352Cp\tK20307 TRAPPC10; trafficking protein particle complex subunit 10"
				},
				{
					"name":"AGOS_AGR310C AGR310Cp\tK20311 TRS65; trafficking protein particle complex II-specific subunit 65"
				},
				{
					"name":"AGOS_AFR385W AFR385Wp\tK20312 TCA17; TRAPP-associated protein TCA17"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-1 complex",
				"children":[
				{
					"name":"AGOS_ADR064C ADR064Cp\tK12391 AP1G1; AP-1 complex subunit gamma-1"
				},
				{
					"name":"AGOS_AFR200W AFR200Wp\tK12392 AP1B1; AP-1 complex subunit beta-1"
				},
				{
					"name":"AGOS_ADL017C ADL017Cp\tK12393 AP1M; AP-1 complex subunit mu"
				},
				{
					"name":"AGOS_AFR124W AFR124Wp\tK12394 AP1S1_2; AP-1 complex subunit sigma 1\/2"
				}
				]
			},
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"AGOS_AFL076W AFL076Wp\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"AGOS_ADR335C ADR335Cp\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"AGOS_AGL061W AGL061Wp\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"AGOS_AAL143W AAL143Wp\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"AP-4 complex"
			},
			{
				"name":"GGA",
				"children":[
				{
					"name":"AGOS_AER243W AER243Wp\tK12404 GGA; ADP-ribosylation factor-binding protein GGA"
				}
				]
			},
			{
				"name":"Aftiphilin\/p200\/gamma-synergin complex"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_AFR071W AFR071Wp\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				},
				{
					"name":"AGOS_ADL033W ADL033Wp\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"AGOS_AGL096W AGL096Wp\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"AGOS_AER188C AER188Cp\tK00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]"
				},
				{
					"name":"AGOS_AAL163W AAL163Wp\tK20318 SYS1; protein SYS1"
				},
				{
					"name":"AGOS_AEL257W AEL257Wp\tK23541 TMEM165; Ca2+\/H+ antiporter, TMEM165\/GDT1 family"
				},
				{
					"name":"AGOS_ABL021C ABL021Cp\tK23542 TMEM199; TMEM199 family protein"
				},
				{
					"name":"AGOS_AAL048W AAL048Wp\tK23543 CCDC115; coiled-coil domain-containing protein 115"
				},
				{
					"name":"AGOS_AGR100W AGR100Wp\tK23544 SERINC1; serine incorporator 1"
				},
				{
					"name":"AGOS_ADR390C ADR390Cp\tK17918 SNX3_12; sorting nexin-3\/12"
				},
				{
					"name":"AGOS_ACL014C ACL014Cp\tK17922 SNX8; sorting nexin-8"
				},
				{
					"name":"AGOS_AEL204C AEL204Cp\tK26678 MON2; protein MON2"
				},
				{
					"name":"AGOS_AGL187W AGL187Wp\tK26680 DOP1; protein dopey"
				},
				{
					"name":"AGOS_AER120C AER120Cp\tK27894 HID1; protein HID1"
				},
				{
					"name":"AGOS_AGR106C AGR106Cp\tK26750 TVP15; golgi apparatus membrane protein TVP15"
				},
				{
					"name":"AGOS_AGL072W AGL072Wp\tK26751 TVP18; golgi apparatus membrane protein TVP18"
				},
				{
					"name":"AGOS_AGR153C AGR153Cp\tK26752 TVP23; golgi apparatus membrane protein TVP23"
				},
				{
					"name":"AGOS_ADR226C ADR226Cp\tK26753 TVP38; golgi apparatus membrane protein TVP38"
				},
				{
					"name":"AGOS_ABL001W ABL001Wp\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"AGOS_AFR018C AFR018Cp\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"AGOS_AFR143C AFR143Cp\tK28986 VPS17; vacuolar protein sorting-associated protein 17"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endoplasmic reticulum (ER) - Golgi transport",
		"children":[
		{
			"name":"Forward pathways",
			"children":[
			{
				"name":"Coat protein complex II (COP-II)",
				"children":[
				{
					"name":"AGOS_AFL114W AFL114Wp\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				},
				{
					"name":"AGOS_ACR199C ACR199Cp\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"AGOS_ADR090W ADR090Wp\tK14005 SEC31; protein transport protein SEC31"
				},
				{
					"name":"AGOS_AEL272W AEL272Wp\tK14006 SEC23; protein transport protein SEC23"
				},
				{
					"name":"AGOS_ACR151W ACR151Wp\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"AGOS_ADL239C ADL239Cp\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"AGOS_AAR048W AAR048Wp\tK14003 PREB; prolactin regulatory element-binding protein"
				},
				{
					"name":"AGOS_AGR202W AGR202Wp\tK20353 SEC16; COPII coat assembly protein SEC16"
				}
				]
			},
			{
				"name":"TRAPP complex I",
				"children":[
				{
					"name":"AGOS_AER154C AER154Cp\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"AGOS_AGR246W AGR246Wp\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"AGOS_AGR300W AGR300Wp\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"AGOS_AFR459W AFR459Wp\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"AGOS_AFR408C AFR408Cp\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"AGOS_ACR265C ACR265Cp\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				}
				]
			},
			{
				"name":"p24 family proteins",
				"children":[
				{
					"name":"AGOS_AER247W AER247Wp\tK20346 TMED4_9_11; p24 family protein alpha"
				},
				{
					"name":"AGOS_AFL005W AFL005Wp\tK20346 TMED4_9_11; p24 family protein alpha"
				},
				{
					"name":"AGOS_AFR165C AFR165Cp\tK20347 TMED2; p24 family protein beta-1"
				},
				{
					"name":"AGOS_ADR026W ADR026Wp\tK14825 TMED5; p24 family protein gamma-2"
				},
				{
					"name":"AGOS_ADR185W ADR185Wp\tK20352 TMED10; p24 family protein delta-1"
				}
				]
			},
			{
				"name":"PDI family proteins",
				"children":[
				{
					"name":"AGOS_AFR718W AFR718Wp\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
				},
				{
					"name":"AGOS_AFR559C AFR559Cp\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
				}
				]
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"AGOS_ABR220W ABR220Wp\tK07874 RAB1A; Ras-related protein Rab-1A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"AGOS_ADL232W ADL232Wp\tK20359 RABAC1; PRA1 family protein 1"
				},
				{
					"name":"AGOS_AFR154C AFR154Cp\tK20372 TBC1D20; TBC1 domain family member 20"
				},
				{
					"name":"AGOS_ADR213C ADR213Cp\tK20360 TBC1D22; TBC1 domain family member 2"
				},
				{
					"name":"AGOS_AFR658W AFR658Wp\tK20362 YIF1; protein transport protein YIF1"
				},
				{
					"name":"AGOS_ACL042W ACL042Wp\tK22939 IER3IP1; immediate early response 3-interacting protein 1"
				},
				{
					"name":"AGOS_AER045C AER045Cp\tK20361 USO1; intracellular protein transport protein USO1"
				}
				]
			},
			{
				"name":"ER-Golgi intermediate compartment (ERGIC) proteins",
				"children":[
				{
					"name":"AGOS_ABR243W ABR243Wp\tK10080 LMAN1; lectin, mannose-binding 1"
				},
				{
					"name":"AGOS_ACR213W ACR213Wp\tK01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]"
				},
				{
					"name":"AGOS_AER165W AER165Wp\tK23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]"
				},
				{
					"name":"AGOS_AER136W AER136Wp\tK20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2"
				},
				{
					"name":"AGOS_ADR389C ADR389Cp\tK20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3"
				},
				{
					"name":"AGOS_AAR149W AAR149Wp\tK20368 CNIH; protein cornichon"
				},
				{
					"name":"AGOS_AGL340C AGL340Cp\tK20369 ERV29; ER-derived vesicles protein"
				},
				{
					"name":"AGOS_ACR038W ACR038Wp\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"AGOS_AAL002W AAL002Wp\tK29081 RER1; Rer1 family protein"
				}
				]
			}
			]
		},
		{
			"name":"Retrieval pathways",
			"children":[
			{
				"name":"Coat protein complex I (COP-I)",
				"children":[
				{
					"name":"AGOS_ADR077C ADR077Cp\tK05236 COPA; coatomer subunit alpha"
				},
				{
					"name":"AGOS_ABL112W ABL112Wp\tK17301 COPB1; coatomer subunit beta"
				},
				{
					"name":"AGOS_AFL118W AFL118Wp\tK17302 COPB2; coatomer subunit beta'"
				},
				{
					"name":"AGOS_AEL193W AEL193Wp\tK17267 COPG; coatomer subunit gamma"
				},
				{
					"name":"AGOS_AFR274C AFR274Cp\tK20471 COPD; coatomer subunit delta"
				},
				{
					"name":"AGOS_ACL037W ACL037Wp\tK17268 COPE; coatomer subunit epsilon"
				},
				{
					"name":"AGOS_AGL016C AGL016Cp\tK20472 COPZ; coatomer subunit zeta"
				}
				]
			},
			{
				"name":"NRZ (DSL1) complex",
				"children":[
				{
					"name":"AGOS_ADL286W ADL286Wp\tK20474 RINT1; RAD50-interacting protein 1"
				},
				{
					"name":"AGOS_AFR652W AFR652Wp\tK11578 ZW10; protein transport protein DSL1\/ZW10"
				},
				{
					"name":"AGOS_AER129C AER129Cp\tK20475 SEC39; protein transport protein SEC39"
				}
				]
			},
			{
				"name":"Golgi to ER traffic proteins (GET)",
				"children":[
				{
					"name":"AGOS_AFR006C AFR006Cp\tK22384 GET1; tail-anchored protein insertion receptor"
				},
				{
					"name":"AGOS_ACL036W ACL036Wp\tK22386 GET2; GET complex subunit GET2"
				},
				{
					"name":"AGOS_ADR285W ADR285Wp\tK01551 arsA; arsenite\/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]"
				},
				{
					"name":"AGOS_AGR265W AGR265Wp\tK23387 GET4; golgi to ER traffic protein 4"
				},
				{
					"name":"AGOS_AEL200C AEL200Cp\tK23388 UBL4; ubiquitin-like protein 4"
				}
				]
			},
			{
				"name":"Rab GTPases"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"AGOS_ADR241C ADR241Cp\tK20476 RIC1; RAB6A-GEF complex partner protein 1"
				},
				{
					"name":"AGOS_AGL179C AGL179Cp\tK20477 RGP1; RAB6A-GEF complex partner protein 2"
				},
				{
					"name":"AGOS_AGL323C AGL323Cp\tK10949 KDELR; ER lumen protein retaining receptor"
				},
				{
					"name":"AGOS_AGR365C AGR365Cp\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"AGOS_ADR213C ADR213Cp\tK20360 TBC1D22; TBC1 domain family member 2"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Oxysterol-binding proteins",
				"children":[
				{
					"name":"AGOS_AER225W AER225Wp\tK20456 OSBP; oxysterol-binding protein 1"
				},
				{
					"name":"AGOS_AGR356W AGR356Wp\tK20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3\/6\/7"
				},
				{
					"name":"AGOS_AEL287C AEL287Cp\tK22285 OSBPL8; oxysterol-binding protein-related protein 8"
				},
				{
					"name":"AGOS_ACR125W ACR125Wp\tK20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9\/10\/11"
				}
				]
			},
			{
				"name":"FXYD proteins"
			},
			{
				"name":"YIPF proteins",
				"children":[
				{
					"name":"AGOS_AEL299W AEL299Wp\tK22940 YIPF1_2; protein YIPF1\/2"
				},
				{
					"name":"AGOS_AAL135C AAL135Cp\tK20363 YIPF5_7; protein YIPF5\/7"
				},
				{
					"name":"AGOS_AFR167W AFR167Wp\tK22943 YIPF6; protein YIPF6"
				}
				]
			},
			{
				"name":"ER membrane protein complex",
				"children":[
				{
					"name":"AGOS_AFR720W AFR720Wp\tK23562 EMC1; ER membrane protein complex subunit 1"
				},
				{
					"name":"AGOS_ACR173W ACR173Wp\tK23563 EMC2; ER membrane protein complex subunit 2"
				},
				{
					"name":"AGOS_AFR429C AFR429Cp\tK23564 EMC3; ER membrane protein complex subunit 3"
				},
				{
					"name":"AGOS_AFR249W AFR249Wp\tK23565 EMC4; ER membrane protein complex subunit 4"
				},
				{
					"name":"AGOS_ADL092W ADL092Wp\tK23566 MMGT1; membrane magnesium transporter 1"
				},
				{
					"name":"AGOS_AAL151C AAL151Cp\tK23567 EMC6; ER membrane protein complex subunit 6"
				}
				]
			},
			{
				"name":"SEC61 complex",
				"children":[
				{
					"name":"AGOS_AFR596W AFR596Wp\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"AGOS_AFR613C AFR613Cp\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"AGOS_ACR234C ACR234Cp\tK09481 SEC61B; protein transport protein SEC61 subunit beta"
				},
				{
					"name":"AGOS_AGR157C AGR157Cp\tK07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins"
				}
				]
			},
			{
				"name":"TRAP complex"
			},
			{
				"name":"Multi-pass translocon (MPT) complex",
				"children":[
				{
					"name":"AGOS_AAR062C AAR062Cp\tK24962 CCDC47; PAT complex subunit CCDC47"
				}
				]
			},
			{
				"name":"Post-GPI attachment to proteins factors (PGAP)",
				"children":[
				{
					"name":"AGOS_AFR521W AFR521Wp\tK05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]"
				},
				{
					"name":"AGOS_AFR678C AFR678Cp\tK23553 PGAP3; post-GPI attachment to proteins factor 3"
				},
				{
					"name":"AGOS_ADL110W ADL110Wp\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				},
				{
					"name":"AGOS_AGL131W AGL131Wp\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_AGL120W AGL120Wp\tK19998 SCFD1; sec1 family domain-containing protein 1"
				},
				{
					"name":"AGOS_ABR219W ABR219Wp\tK20724 TMEM33; transmembrane protein 33"
				},
				{
					"name":"AGOS_AFR113W AFR113Wp\tK20724 TMEM33; transmembrane protein 33"
				},
				{
					"name":"AGOS_AGL115W AGL115Wp\tK21848 ARV1; lipid intermediate transporter"
				},
				{
					"name":"AGOS_AFR247W AFR247Wp\tK21849 KEG1; beta-1,6-glucan synthesis-associated protein KEG1"
				},
				{
					"name":"AGOS_AFR545W AFR545Wp\tK21850 KRE6; beta-glucan synthesis-associated protein KRE6"
				},
				{
					"name":"AGOS_ACL165C ACL165Cp\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"AGOS_AER167W AER167Wp\tK23292 LNPK; endoplasmic reticulum junction formation protein lunapark"
				},
				{
					"name":"AGOS_AFR043W AFR043Wp\tK26681 INSIG; insulin-induced protein"
				},
				{
					"name":"AGOS_AGR337W AGR337Wp\tK26683 GOLT1; vesicle transport protein GOT1"
				},
				{
					"name":"AGOS_AGR264C AGR264Cp\tK22698 SEY1; protein SEY1 [EC:3.6.5.-]"
				},
				{
					"name":"AGOS_ABR107W ABR107Wp\tK29087 NVJ2; nucleus-vacuole junction protein 2"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Autophagy",
		"children":[
		{
			"name":"Autophagosome formation proteins",
			"children":[
			{
				"name":"ULK complex",
				"children":[
				{
					"name":"AGOS_AEL277C AEL277Cp\tK08331 ATG13; autophagy-related protein 13"
				}
				]
			},
			{
				"name":"Atg1 complex",
				"children":[
				{
					"name":"AGOS_ACL054W ACL054Wp\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_AEL277C AEL277Cp\tK08331 ATG13; autophagy-related protein 13"
				},
				{
					"name":"AGOS_AER106C AER106Cp\tK08329 ATG17; autophagy-related protein 17"
				},
				{
					"name":"AGOS_AAL098W AAL098Wp\tK21143 ATG29; autophagy-related protein 29"
				},
				{
					"name":"AGOS_AER409C AER409Cp\tK21144 ATG31; autophagy-related protein 31"
				}
				]
			},
			{
				"name":"PI3K complex",
				"children":[
				{
					"name":"AGOS_AGL113C AGL113Cp\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"AGOS_ADL316C ADL316Cp\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_ADL381W ADL381Wp\tK08335 ATG14; autophagy-related protein 14"
				},
				{
					"name":"AGOS_ACR154W ACR154Wp\tK08334 BECN; beclin"
				},
				{
					"name":"AGOS_ADR074C ADR074Cp\tK21145 ATG38; autophagy-related protein 38"
				}
				]
			},
			{
				"name":"ATG9 transmembrane protein",
				"children":[
				{
					"name":"AGOS_ADR071W ADR071Wp\tK17907 ATG9; autophagy-related protein 9"
				}
				]
			},
			{
				"name":"Atg18-Atg2 complex",
				"children":[
				{
					"name":"AGOS_AAL119W AAL119Wp\tK17908 WIPI1_2; autophagy-related protein 18"
				},
				{
					"name":"AGOS_ABR189W ABR189Wp\tK17908 WIPI1_2; autophagy-related protein 18"
				},
				{
					"name":"AGOS_ABL208W ABL208Wp\tK17906 ATG2; autophagy-related protein 2"
				}
				]
			},
			{
				"name":"Atg12 conjugation proteins",
				"children":[
				{
					"name":"AGOS_AAR160W AAR160Wp\tK08336 ATG12; ubiquitin-like protein ATG12"
				},
				{
					"name":"AGOS_AER298C AER298Cp\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"AGOS_ACL066C ACL066Cp\tK08338 ATG10; ubiquitin-like-conjugating enzyme ATG10"
				},
				{
					"name":"AGOS_ACR131C ACR131Cp\tK08339 ATG5; autophagy-related protein 5"
				},
				{
					"name":"AGOS_AFL186W AFL186Wp\tK08340 ATG16; autophagy-related protein 16"
				}
				]
			},
			{
				"name":"Atg8 conjugation proteins",
				"children":[
				{
					"name":"AGOS_AER396W AER396Wp\tK08341 GABARAP; GABA(A) receptor-associated protein"
				},
				{
					"name":"AGOS_ABL191W ABL191Wp\tK08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]"
				},
				{
					"name":"AGOS_AER298C AER298Cp\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"AGOS_AFL178W AFL178Wp\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
				}
				]
			}
			]
		},
		{
			"name":"Cytoplasm to vacuolar targeting (CVT) pathway",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"AGOS_ABL035C ABL035Cp\tK01268 LAP4; aminopeptidase I [EC:3.4.11.22]"
				},
				{
					"name":"AGOS_AGR385C AGR385Cp\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				}
				]
			},
			{
				"name":"Cargo receptors",
				"children":[
				{
					"name":"AGOS_AER029C AER029Cp\tK21997 ATG19_34; autophagy-related protein 19\/34"
				}
				]
			},
			{
				"name":"Scaffold protein",
				"children":[
				{
					"name":"AGOS_ADL307W ADL307Wp\tK08330 ATG11; autophagy-related protein 11"
				}
				]
			},
			{
				"name":"Other Cvt associated proteins",
				"children":[
				{
					"name":"AGOS_ADL293W ADL293Wp\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"AGOS_ADR192C ADR192Cp\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"AGOS_ACR074W ACR074Wp\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"AGOS_AAR046C AAR046Cp\tK17900 ATG15; lipase ATG15 [EC:3.1.1.3]"
				},
				{
					"name":"AGOS_AER116C AER116Cp\tK17909 ATG23; autophagy-related protein 23"
				},
				{
					"name":"AGOS_AEL138C AEL138Cp\tK21141 ATG27; autophagy-related protein 27"
				},
				{
					"name":"AGOS_AEL048W AEL048Wp\tK08332 VAC8; vacuolar protein 8"
				}
				]
			}
			]
		},
		{
			"name":"Mitophagy",
			"children":[
			{
				"name":"Cargo receptors",
				"children":[
				{
					"name":"AGOS_AFR283W AFR283Wp\tK17984 ATG32; autophagy-related protein 32"
				}
				]
			},
			{
				"name":"Scaffold proteins",
				"children":[
				{
					"name":"AGOS_ADL307W ADL307Wp\tK08330 ATG11; autophagy-related protein 11"
				}
				]
			},
			{
				"name":"PINK1-Parkin associated proteins",
				"children":[
				{
					"name":"AGOS_ABR195C ABR195Cp\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"Other mitophagy associated  proteins",
				"children":[
				{
					"name":"AGOS_AER143W AER143Wp\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"AGOS_AFR279C AFR279Cp\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"AGOS_AFR716C AFR716Cp\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"AGOS_ADR109W ADR109Wp\tK22255 ATPIF1; ATPase inhibitor, mitochondrial"
				},
				{
					"name":"AGOS_AER365W AER365Wp\tK17771 TOM7; mitochondrial import receptor subunit TOM7"
				},
				{
					"name":"AGOS_AEL283C AEL283Cp\tK19717 ATG33; autophagy-related protein 33"
				}
				]
			}
			]
		},
		{
			"name":"Pexophagy",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"AGOS_ADR296C ADR296Cp\tK13336 PEX3; peroxin-3"
				},
				{
					"name":"AGOS_AGR381C AGR381Cp\tK13343 PEX14; peroxin-14"
				}
				]
			},
			{
				"name":"Cargo receptors",
				"children":[
				{
					"name":"AGOS_AEL146C AEL146Cp\tK22258 ATG36; autophagy-related protein 36"
				}
				]
			},
			{
				"name":"Other pexophagy associated proteins",
				"children":[
				{
					"name":"AGOS_AFR371W AFR371Wp\tK13338 PEX1; peroxin-1 [EC:3.6.4.-]"
				},
				{
					"name":"AGOS_AGR394W AGR394Wp\tK13339 PEX6; peroxin-6 [EC:3.6.4.-]"
				},
				{
					"name":"AGOS_ACR280C ACR280Cp\tK22260 PEX15; peroxin-15"
				}
				]
			}
			]
		},
		{
			"name":"Aggrephagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold proteins"
			},
			{
				"name":"Other aggrephagy associated proteins",
				"children":[
				{
					"name":"AGOS_AFR158W AFR158Wp\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"AGOS_ADL216C ADL216Cp\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
				}
				]
			}
			]
		},
		{
			"name":"Xenophagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Other xenophagy associated proteins"
			}
			]
		},
		{
			"name":"ER-phagy",
			"children":[
			{
				"name":"ER-phagy recepters",
				"children":[
				{
					"name":"AGOS_ABR196C ABR196Cp\tK12275 SEC62; translocation protein SEC62"
				}
				]
			},
			{
				"name":"Other ER-phagy associated proteins",
				"children":[
				{
					"name":"AGOS_AAL106W AAL106Wp\tK17278 PGRMC1_2; membrane-associated progesterone receptor component"
				},
				{
					"name":"AGOS_AER144C AER144Cp\tK17278 PGRMC1_2; membrane-associated progesterone receptor component"
				}
				]
			},
			{
				"name":"ER stress-related proteins",
				"children":[
				{
					"name":"AGOS_ACR038W ACR038Wp\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"AGOS_AGR320W AGR320Wp\tK03237 EIF2S1; translation initiation factor 2 subunit 1"
				},
				{
					"name":"AGOS_AER069W AER069Wp\tK14009 BCAP31; B-cell receptor-associated protein 31"
				}
				]
			}
			]
		},
		{
			"name":"Chaperone mediated autophagy (CMA)",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"AGOS_AFR211C AFR211Cp\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
				},
				{
					"name":"AGOS_AER031C AER031Cp\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"AGOS_ACR056W ACR056Wp\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"AGOS_AER228C AER228Cp\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"AGOS_ADR368W ADR368Wp\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"AGOS_ABL129W ABL129Wp\tK04523 UBQLN; ubiquilin"
				}
				]
			},
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Chaperones",
				"children":[
				{
					"name":"AGOS_ABL174C ABL174Cp\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"AGOS_AER187W AER187Wp\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"AGOS_AFR114W AFR114Wp\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"AGOS_AFL148C AFL148Cp\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"Co-chaperones"
			},
			{
				"name":"Other CMA associated proteins",
				"children":[
				{
					"name":"AGOS_ADL370C ADL370Cp\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"AGOS_AER022W AER022Wp\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
				},
				{
					"name":"AGOS_AGL328C AGL328Cp\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
				}
				]
			}
			]
		},
		{
			"name":"Other autophagy associated proteins",
			"children":[
			{
				"name":"RNautophagy\/DNautophagy"
			},
			{
				"name":"Micronucleophagy",
				"children":[
				{
					"name":"AGOS_AEL048W AEL048Wp\tK08332 VAC8; vacuolar protein 8"
				}
				]
			},
			{
				"name":"Midbophagy"
			},
			{
				"name":"Glycophagy"
			},
			{
				"name":"TRIM-directed selective autophagy"
			},
			{
				"name":"ER-mitochondria tethering complex",
				"children":[
				{
					"name":"AGOS_ABR195C ABR195Cp\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"mTORC1 complex",
				"children":[
				{
					"name":"AGOS_AFR420W AFR420Wp\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_AAL009C AAL009Cp\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"AGOS_ADR331C ADR331Cp\tK07204 RAPTOR; regulatory associated protein of mTOR"
				},
				{
					"name":"AGOS_AFL054C AFL054Cp\tK25579 TCO89; target of rapamycin complex 1 subunit TCO89"
				}
				]
			},
			{
				"name":"mTORC2 complex",
				"children":[
				{
					"name":"AGOS_AFR420W AFR420Wp\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"AGOS_AAL009C AAL009Cp\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"AGOS_AER023C AER023Cp\tK20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1\/AVO1"
				},
				{
					"name":"AGOS_ABR214C ABR214Cp\tK08267 RICTOR; rapamycin-insensitive companion of mTOR"
				},
				{
					"name":"AGOS_ADR151W ADR151Wp\tK25576 AVO2; target of rapamycin complex 2 subunit AVO2"
				},
				{
					"name":"AGOS_AEL172W AEL172Wp\tK25577 BIT61_2; target of rapamycin complex 2 subunit BIT61\/BIT2"
				}
				]
			},
			{
				"name":"SEACIT\/GATOR1 complex",
				"children":[
				{
					"name":"AGOS_ABL079C ABL079Cp\tK20404 DEPDC5; SEA\/GATOR complex protein SEA1\/DEPDC5"
				},
				{
					"name":"AGOS_ACR009W ACR009Wp\tK20405 NPRL2; nitrogen permease regulator 2"
				},
				{
					"name":"AGOS_AGL039W AGL039Wp\tK20406 NPRL3; nitrogen permease regulator 3"
				}
				]
			},
			{
				"name":"SEACAT\/GATOR2 complex",
				"children":[
				{
					"name":"AGOS_ADL186C ADL186Cp\tK20408 WDR24; SEA\/GATOR complex protein SEA2\/WDR24"
				},
				{
					"name":"AGOS_AGR067W AGR067Wp\tK20409 WDR59; SEA\/GATOR complex protein SEA3\/WDR59"
				},
				{
					"name":"AGOS_ACR192C ACR192Cp\tK20407 MIOS; SEA\/GATOR complex protein SEA4\/MIOS"
				},
				{
					"name":"AGOS_AFL038C AFL038Cp\tK14299 SEH1; nucleoporin SEH1"
				},
				{
					"name":"AGOS_ACR199C ACR199Cp\tK14004 SEC13; protein transport protein SEC13"
				}
				]
			},
			{
				"name":"KICSTOR complex"
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"AGOS_ABR220W ABR220Wp\tK07874 RAB1A; Ras-related protein Rab-1A"
				},
				{
					"name":"AGOS_AGL021W AGL021Wp\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_ADR099C ADR099Cp\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
				},
				{
					"name":"AGOS_ABR072W ABR072Wp\tK17606 IGBP1; immunoglobulin-binding protein 1"
				},
				{
					"name":"AGOS_AFR714W AFR714Wp\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"AGOS_ACR051C ACR051Cp\tK14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)"
				},
				{
					"name":"AGOS_AER380C AER380Cp\tK14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)"
				},
				{
					"name":"AGOS_ADL134W ADL134Wp\tK22991 WDR45; WD repeat-containing protein 45"
				},
				{
					"name":"AGOS_AAR096W AAR096Wp\tK23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Others",
		"children":[
		{
			"name":"NADPH oxidases (Nox) and associated proteins",
			"children":[
			{
				"name":"NADPH oxidases"
			},
			{
				"name":"Nox associated proteins"
			}
			]
		},
		{
			"name":"Actin-binding proteins",
			"children":[
			{
				"name":"Myosins",
				"children":[
				{
					"name":"AGOS_AEL306C AEL306Cp\tK10356 MYO1; myosin I"
				},
				{
					"name":"AGOS_ADR354W ADR354Wp\tK10357 MYO5; myosin V"
				}
				]
			},
			{
				"name":"Arp2\/3 complex",
				"children":[
				{
					"name":"AGOS_AFL022W AFL022Wp\tK05757 ARPC1A_B; actin related protein 2\/3 complex, subunit 1A\/1B"
				},
				{
					"name":"AGOS_AGL221W AGL221Wp\tK05758 ARPC2; actin related protein 2\/3 complex, subunit 2"
				},
				{
					"name":"AGOS_AFR584C AFR584Cp\tK05756 ARPC3; actin related protein 2\/3 complex, subunit 3"
				},
				{
					"name":"AGOS_ACL092C ACL092Cp\tK05755 ARPC4; actin related protein 2\/3 complex, subunit 4"
				},
				{
					"name":"AGOS_ADL061W ADL061Wp\tK05754 ARPC5; actin related protein 2\/3 complex, subunit 5"
				},
				{
					"name":"AGOS_ADR316W ADR316Wp\tK17260 ACTR2; actin-related protein 2"
				},
				{
					"name":"AGOS_AFR419C AFR419Cp\tK18584 ACTR3; actin-related protein 3"
				}
				]
			},
			{
				"name":"Nucleation-promoting factors (NPFs)",
				"children":[
				{
					"name":"AGOS_AGR285W AGR285Wp\tK23612 WASL; neural Wiskott-Aldrich syndrome protein"
				},
				{
					"name":"AGOS_AGL237C AGL237Cp\tK20520 DBNL; drebrin-like protein"
				},
				{
					"name":"AGOS_ADR018C ADR018Cp\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"AGOS_AER140C AER140Cp\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"AGOS_AFR140C AFR140Cp\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"AGOS_AGR170C AGR170Cp\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"AGOS_AGR306C AGR306Cp\tK20521 BBC1; myosin tail region-interacting protein MTI1"
				},
				{
					"name":"AGOS_AFR320W AFR320Wp\tK20522 LSB1_2; LAS seventeen-binding protein 1\/2"
				},
				{
					"name":"AGOS_AEL017W AEL017Wp\tK20523 SH3YL1; SH3 domain-containing YSC84-like protein 1"
				},
				{
					"name":"AGOS_AFR709C AFR709Cp\tK20524 LSB5; LAS seventeen-binding protein 5"
				},
				{
					"name":"AGOS_AFR087W AFR087Wp\tK13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AGOS_ACL168C ACL168Cp\tK05759 PFN; profilin"
				},
				{
					"name":"AGOS_ADR235W ADR235Wp\tK05765 CFL; cofilin"
				},
				{
					"name":"AGOS_AFR061W AFR061Wp\tK17261 CAP1_2; adenylyl cyclase-associated protein"
				},
				{
					"name":"AGOS_ADR145C ADR145Cp\tK10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]"
				},
				{
					"name":"AGOS_ADR409W ADR409Wp\tK20526 TAGLN; transgelin"
				}
				]
			}
			]
		},
		{
			"name":"Mucins",
			"children":[
			{
				"name":"Membrane bound mucins"
			},
			{
				"name":"Secretory mucins"
			}
			]
		},
		{
			"name":"MARVEL domain-containing proteins"
		},
		{
			"name":"Specific organelles associated proteins",
			"children":[
			{
				"name":"Melanosome"
			},
			{
				"name":"Auto phagosome"
			},
			{
				"name":"Lipid droplets",
				"children":[
				{
					"name":"AGOS_AAR165W AAR165Wp\tK28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]"
				},
				{
					"name":"AGOS_AGR350C AGR350Cp\tK28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]"
				}
				]
			},
			{
				"name":"Mitochondrion"
			}
			]
		},
		{
			"name":"Rho GTPase associated proteins",
			"children":[
			{
				"name":"Rho GTPase-activating proteins",
				"children":[
				{
					"name":"AGOS_AFR616W AFR616Wp\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				}
				]
			},
			{
				"name":"Rho guanine nucleotide exchange factors (GEFs)",
				"children":[
				{
					"name":"AGOS_AER102W AER102Wp\tK05727 DOCK3; dedicator of cytokinesis protein 3"
				},
				{
					"name":"AGOS_ABR061C ABR061Cp\tK28415 DENND11; DENN domain-containing protein 11"
				}
				]
			}
			]
		}
		]
	}
	]
}