{
	"name":"aoi01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"AORI_6554 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"AORI_0457 murB; UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"AORI_2299 murC; UDP-N-acetylmuramate--alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"AORI_2296 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"AORI_2293 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"AORI_8112 ddl; D-alanine-D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"AORI_0725 alr; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"AORI_6488 murI; glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"AORI_3893 ldcA; muramoyltetrapeptide carboxypeptidase\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"AORI_2295 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"AORI_2298 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"AORI_4105 bacA; undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"AORI_8103 mviN; virulence factor\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)"
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"AORI_2292 ftsI; cell division protein FtsI (penicillin-binding protein 3)\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			},
			{
				"name":"AORI_0046 peptidoglycan glycosyltransferase\tK05364 pbpA; penicillin-binding protein A"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"AORI_0850 dacC; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5\/6)\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"AORI_7525 dacB; D-alanyl-D-alanine carboxypeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"AORI_0047 ftsW; cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"AORI_2297 ftsW; cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase"
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"AORI_1473 vanX; D-alanyl-D-alanine dipeptidase\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
			},
			{
				"name":"AORI_2227 vanX; D-alanyl-D-alanine dipeptidase\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
			},
			{
				"name":"AORI_2620 vanY; peptidase M15B and M15C dd-carboxypeptidase VanY\/endolysin\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
			},
			{
				"name":"AORI_3718 putative muramoyl-pentapeptide carboxypeptidase\tK08640 E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
			}
			]
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"AORI_3634 NLP\/P60-family protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"AORI_5714 NLP\/P60-family protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"AORI_3765 hypothetical protein\tK21473 ripA; peptidoglycan DL-endopeptidase RipA [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Sortase",
			"children":[
			{
				"name":"AORI_1802 srtA; sortase A\tK07284 srtA; sortase A [EC:3.4.22.70]"
			}
			]
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"AORI_2705 UPF0755 protein\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"AORI_7686 amiA; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"AORI_8109 amiA; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein"
		}
		]
	}
	]
}