{
	"name":"aplc00536",
	"children":[
	{
		"name":"Heparan sulfate \/ Heparin",
		"children":[
		{
			"name":"Cytokines"
		},
		{
			"name":"Chemokines",
			"children":[
			{
				"name":"------  CCL12; C-C motif chemokine 12 [MMU:20293] [KO:K14624]"
			}
			]
		},
		{
			"name":"Adhesion molecules of cell surface",
			"children":[
			{
				"name":"110986479 neural cell adhesion molecule 1-like isoform X1\tK06491 NCAM; neural cell adhesion molecule"
			}
			]
		},
		{
			"name":"Morphogens",
			"children":[
			{
				"name":"110973657 bone morphogenetic protein 2-like\tK21283 BMP2; bone morphogenetic protein 2"
			},
			{
				"name":"110978423 bone morphogenetic protein 2-like\tK21283 BMP2; bone morphogenetic protein 2"
			},
			{
				"name":"110986197 protein DVR-1 homolog\tK16621 BMP7; bone morphogenetic protein 7"
			},
			{
				"name":"110984810 protein Wnt-1-like\tK03209 WNT1; wingless-type MMTV integration site family, member 1"
			},
			{
				"name":"110984921 protein Wnt-2b-A-like\tK00182 WNT2; wingless-type MMTV integration site family, member 2"
			},
			{
				"name":"110985570 protein Wnt-3a-like\tK00312 WNT3; wingless-type MMTV integration site family, member 3"
			},
			{
				"name":"110984610 protein Wnt-4-like\tK00408 WNT4; wingless-type MMTV integration site family, member 4"
			},
			{
				"name":"110974216 protein Wnt-5b-like\tK00444 WNT5; wingless-type MMTV integration site family, member 5"
			},
			{
				"name":"110984744 protein Wnt-6-like\tK00445 WNT6; wingless-type MMTV integration site family, member 6"
			},
			{
				"name":"110981351 protein Wnt-7a-like\tK00572 WNT7; wingless-type MMTV integration site family, member 7"
			},
			{
				"name":"110988535 protein Wnt-7b-like\tK00572 WNT7; wingless-type MMTV integration site family, member 7"
			},
			{
				"name":"110980473 protein Wnt-8-like\tK00714 WNT8; wingless-type MMTV integration site family, member 8"
			},
			{
				"name":"110983723 protein Wnt-9a-like\tK01064 WNT9; wingless-type MMTV integration site family, member 9"
			},
			{
				"name":"110983430 protein Wnt-10b-like\tK01357 WNT10; wingless-type MMTV integration site family, member 10"
			},
			{
				"name":"110986453 protein Wnt-16-like\tK01558 WNT16; wingless-type MMTV integration site family, member 16"
			}
			]
		},
		{
			"name":"Growth factors\/receptors",
			"children":[
			{
				"name":"110983759 fibroblast growth factor 1-like\tK18497 FGF2; fibroblast growth factor 2"
			},
			{
				"name":"110977170 fibroblast growth factor 7-like\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"110979880 fibroblast growth factor 18-like isoform X1\tK04358 FGF; fibroblast growth factor"
			},
			{
				"name":"110973888 fibroblast growth factor receptor-like isoform X1\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"110988178 tyrosine kinase receptor Cad96Ca-like\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"110988925 vascular endothelial growth factor receptor kdr-like isoform X1\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"110988938 tyrosine kinase receptor Cad96Ca-like\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"110983506 LOW QUALITY PROTEIN: fibroblast growth factor receptor 3-like\tK05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]"
			},
			{
				"name":"110988926 macrophage-stimulating protein receptor-like\tK05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"Extracellular matrix molecules",
			"children":[
			{
				"name":"110977321 fibrillin-2-like isoform X1\tK23342 FBN2_3; fibrillin 2\/3"
			},
			{
				"name":"------  LAMA5; laminin, alpha 5 [HSA:3911] [KO:K06240]"
			},
			{
				"name":"110979465 SPARC-related modular calcium-binding protein 1-like isoform X1\tK24354 SMOC; SPARC-related modular calcium-binding protein"
			},
			{
				"name":"110979481 thrombospondin-2-like\tK16857 THBS1; thrombospondin 1"
			},
			{
				"name":"110987632 cartilage oligomeric matrix protein-like\tK04659 THBS2S; thrombospondin 2\/3\/4\/5"
			},
			{
				"name":"110987416 collagen alpha-2(I) chain-like\tK06236 COL1A; collagen type I alpha"
			},
			{
				"name":"110978062 uncharacterized protein LOC110978062 isoform X1\tK19719 COL2A; collagen type II alpha"
			},
			{
				"name":"110978064 collagen alpha-1(II) chain-like\tK19719 COL2A; collagen type II alpha"
			},
			{
				"name":"110978065 collagen alpha-1(I) chain-like\tK19719 COL2A; collagen type II alpha"
			},
			{
				"name":"110981655 collagen alpha-5(IV) chain-like\tK06237 COL4A; collagen type IV alpha"
			},
			{
				"name":"110981727 collagen alpha-2(IV) chain-like\tK06237 COL4A; collagen type IV alpha"
			},
			{
				"name":"110981442 collagen alpha-1(I) chain-like\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			},
			{
				"name":"110986786 collagen alpha-1(I) chain-like isoform X1\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			},
			{
				"name":"110986800 collagen alpha-1(I) chain-like\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			},
			{
				"name":"110987500 collagen alpha-1(II) chain-like isoform X1\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			},
			{
				"name":"110987536 collagen alpha-1(I) chain-like isoform X1\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			},
			{
				"name":"110990209 collagen alpha-1(XI) chain-like isoform X1\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			},
			{
				"name":"110991125 acetylcholinesterase collagenic tail peptide-like isoform X1\tK26586 COLQ; acetylcholinesterase collagenic tail peptide"
			}
			]
		},
		{
			"name":"Axon guidance molecules",
			"children":[
			{
				"name":"110979695 netrin-1-like isoform X1\tK06843 NTN1; netrin 1"
			},
			{
				"name":"110977078 slit homolog 2 protein-like isoform X1\tK06839 SLIT2; slit 2"
			},
			{
				"name":"------  SEMA5A; semaphorin 5A [HSA:9037] [KO:K06841]"
			}
			]
		},
		{
			"name":"Coagulation and fibrinolysis",
			"children":[
			{
				"name":"110974931 uncharacterized protein LOC110974931 isoform X1\tK01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]"
			}
			]
		},
		{
			"name":"Enzymes",
			"children":[
			{
				"name":"110974251 heparanase-like isoform X1\tK07964 HPSE; heparanase [EC:3.2.1.166]"
			},
			{
				"name":"110984533 heparanase-like\tK07964 HPSE; heparanase [EC:3.2.1.166]"
			},
			{
				"name":"110973932 hyaluronidase-1-like isoform X1\tK01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]"
			},
			{
				"name":"110990066 hyaluronidase-1-like\tK01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]"
			},
			{
				"name":"110983835 superoxide dismutase [Cu-Zn]-like\tK16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]"
			}
			]
		},
		{
			"name":"Microbial pathogens",
			"children":[
			{
				"name":"------  Dengue virus, envelope protein"
			},
			{
				"name":"------  Foot-and-mouth disease virus - type O, VP3"
			},
			{
				"name":"------  penetrin"
			},
			{
				"name":"------  Borrelia burgdorferi"
			},
			{
				"name":"------  Chlamydia trachomatis"
			},
			{
				"name":"------  Neisseria gonorrhoeae"
			},
			{
				"name":"------  Leishmania amazonensis"
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"110983535 amyloid beta A4 protein-like\tK04520 APP; amyloid beta A4 protein"
			},
			{
				"name":"110975330 cathepsin B-like\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"110979509 cathepsin B-like\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"110979580 cathepsin B-like\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"110985061 cathepsin B-like isoform X1\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"110985066 cathepsin B-like\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"110986094 cathepsin B-like cysteine proteinase 3\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"110981857 sodium\/calcium exchanger 3-like\tK05849 SLC8A; solute carrier family 8 (sodium\/calcium exchanger)"
			},
			{
				"name":"110986339 sodium\/calcium exchanger 1-like isoform X1\tK05849 SLC8A; solute carrier family 8 (sodium\/calcium exchanger)"
			}
			]
		}
		]
	},
	{
		"name":"Hyaluronan",
		"children":[
		{
			"name":"Cell surface receptors",
			"children":[
			{
				"name":"110981710 ADP-ribosyl cyclase\/cyclic ADP-ribose hydrolase-like\tK01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]"
			},
			{
				"name":"110983673 stabilin-2-like isoform X1\tK19013 STAB2; stabilin-2"
			}
			]
		},
		{
			"name":"Extracellular matrix or blood plasma proteins",
			"children":[
			{
				"name":"110987016 complement component 1 Q subcomponent-binding protein, mitochondrial-like\tK15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial"
			},
			{
				"name":"110986944 inter-alpha-trypsin inhibitor heavy chain H3-like\tK24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3"
			},
			{
				"name":"110986946 inter-alpha-trypsin inhibitor heavy chain H3-like\tK24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3"
			}
			]
		},
		{
			"name":"Intracellular proteins",
			"children":[
			{
				"name":"110987503 hsp90 co-chaperone Cdc37-like\tK09554 CDC37; cell division cycle protein 37"
			}
			]
		}
		]
	}
	]
}