{
	"name":"bbif03021",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"RNA polymerase II system",
			"children":[
			{
				"name":"RNA polymerase II",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"117208074 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
					},
					{
						"name":"117214252 DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
					},
					{
						"name":"117205997 DNA-directed RNA polymerase II subunit RPB11 isoform X1\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
					}
					]
				},
				{
					"name":"Pol II specific subunits",
					"children":[
					{
						"name":"117205885 DNA-directed RNA polymerase II subunit RPB7 isoform X1\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"117206414 DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
					},
					{
						"name":"117210890 DNA-directed RNA polymerase II subunit GRINL1A\tK21987 POLR2M; DNA-directed RNA polymerase II subunit GRINL1A"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"117217252 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"117205960 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"117205462 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"117213502 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"117209007 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				},
				{
					"name":"Pol IV and V specific subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIA",
					"children":[
					{
						"name":"117213851 transcription initiation factor IIA subunit 1 isoform X1\tK03122 TFIIA1; transcription initiation factor TFIIA large subunit"
					},
					{
						"name":"117215081 transcription initiation factor IIA subunit 2\tK03123 TFIIA2; transcription initiation factor TFIIA small subunit"
					}
					]
				},
				{
					"name":"TFIIB",
					"children":[
					{
						"name":"117209032 transcription initiation factor IIB isoform X1\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFIID",
					"children":[
					{
						"name":"117204087 TATA box-binding protein-like protein 1\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117205487 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117212013 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117210056 transcription initiation factor TFIID subunit 1 isoform X1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
					},
					{
						"name":"117207324 transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"117214579 transcription initiation factor TFIID subunit 3 isoform X1\tK14650 TAF3; transcription initiation factor TFIID subunit 3"
					},
					{
						"name":"117204350 transcription initiation factor TFIID subunit 4 isoform X1\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"117213978 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"117215738 TAF5-like RNA polymerase II p300\/CBP-associated factor-associated factor 65 kDa subunit 5L isoform X1\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"117207082 uncharacterized protein LOC117207082\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"117211324 transcription initiation factor TFIID subunit 6-like\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"117206976 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"117205645 transcription initiation factor TFIID subunit 8\tK14649 TAF8; transcription initiation factor TFIID subunit 8"
					},
					{
						"name":"117209484 transcription initiation factor TFIID subunit 9-like\tK03133 TAF9B; transcription initiation factor TFIID subunit 9B"
					},
					{
						"name":"117209648 transcription initiation factor TFIID subunit 9-like\tK03133 TAF9B; transcription initiation factor TFIID subunit 9B"
					},
					{
						"name":"117217007 transcription initiation factor TFIID subunit 10-like\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"117211876 transcription initiation factor TFIID subunit 11\tK03135 TAF11; transcription initiation factor TFIID subunit 11"
					},
					{
						"name":"117208817 transcription initiation factor TFIID subunit 12b isoform X1\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"117210806 transcription initiation factor TFIID subunit 13 isoform X1\tK03127 TAF13; transcription initiation factor TFIID subunit 13"
					}
					]
				},
				{
					"name":"TFIIE",
					"children":[
					{
						"name":"117209581 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					},
					{
						"name":"117209749 general transcription factor IIE subunit 2\tK03137 TFIIE2; transcription initiation factor TFIIE subunit beta"
					}
					]
				},
				{
					"name":"TFIIF",
					"children":[
					{
						"name":"117214584 general transcription factor IIF subunit 1\tK03138 TFIIF1; transcription initiation factor TFIIF subunit alpha"
					},
					{
						"name":"117212913 general transcription factor IIF subunit 2\tK03139 TFIIF2; transcription initiation factor TFIIF subunit beta [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"TFIIH",
					"children":[
					{
						"name":"117212217 general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"117208948 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"117216678 general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"117210403 general transcription factor IIH subunit 4 isoform X1\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"117213956 general transcription and DNA repair factor IIH helicase subunit XPB isoform X1\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"117206522 general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"117207304 general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"117213775 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"117209034 CDK-activating kinase assembly factor MAT1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					},
					{
						"name":"117216293 cyclin-H\tK06634 CCNH; cyclin H"
					}
					]
				}
				]
			},
			{
				"name":"Mediator complex",
				"children":[
				{
					"name":"Head",
					"children":[
					{
						"name":"117205096 mediator of RNA polymerase II transcription subunit 6 isoform X1\tK15128 MED6; mediator of RNA polymerase II transcription subunit 6"
					},
					{
						"name":"117212993 mediator of RNA polymerase II transcription subunit 8 isoform X1\tK15129 MED8; mediator of RNA polymerase II transcription subunit 8"
					},
					{
						"name":"117212434 mediator of RNA polymerase II transcription subunit 11\tK15131 MED11; mediator of RNA polymerase II transcription subunit 11"
					},
					{
						"name":"117207369 mediator of RNA polymerase II transcription subunit 17\tK15133 MED17; mediator of RNA polymerase II transcription subunit 17"
					},
					{
						"name":"117205951 mediator of RNA polymerase II transcription subunit 18\tK15135 MED18; mediator of RNA polymerase II transcription subunit 18"
					},
					{
						"name":"117207062 mediator of RNA polymerase II transcription subunit 19\tK15137 MED19; mediator of RNA polymerase II transcription subunit 19"
					},
					{
						"name":"117206063 mediator of RNA polymerase II transcription subunit 22-like\tK15139 MED22; mediator of RNA polymerase II transcription subunit 22"
					},
					{
						"name":"117210133 mediator of RNA polymerase II transcription subunit 28-like\tK15141 MED28; mediator of RNA polymerase II transcription subunit 28"
					},
					{
						"name":"117205138 mediator of RNA polymerase II transcription subunit 30-like isoform X1\tK15143 MED30; mediator of RNA polymerase II transcription subunit 30"
					}
					]
				},
				{
					"name":"Middle",
					"children":[
					{
						"name":"117210715 mediator of RNA polymerase II transcription subunit 1 isoform X1\tK15144 MED1; mediator of RNA polymerase II transcription subunit 1"
					},
					{
						"name":"117204116 mediator of RNA polymerase II transcription subunit 4\tK15146 MED4; mediator of RNA polymerase II transcription subunit 4"
					},
					{
						"name":"117211205 mediator of RNA polymerase II transcription subunit 7\tK15148 MED7; mediator of RNA polymerase II transcription subunit 7"
					},
					{
						"name":"117205876 mediator of RNA polymerase II transcription subunit 9\tK15149 MED9; mediator of RNA polymerase II transcription subunit 9"
					},
					{
						"name":"117207744 mediator of RNA polymerase II transcription subunit 10\tK15151 MED10; mediator of RNA polymerase II transcription subunit 10"
					},
					{
						"name":"117207075 mediator of RNA polymerase II transcription subunit 21 isoform X1\tK15152 MED21; mediator of RNA polymerase II transcription subunit 21"
					},
					{
						"name":"117213962 mediator of RNA polymerase II transcription subunit 31\tK15153 MED31; mediator of RNA polymerase II transcription subunit 31"
					}
					]
				},
				{
					"name":"Tail",
					"children":[
					{
						"name":"117211921 mediator of RNA polymerase II transcription subunit 14\tK15156 MED14; mediator of RNA polymerase II transcription subunit 14"
					},
					{
						"name":"117210676 mediator of RNA polymerase II transcription subunit 15\tK15157 MED15; mediator of RNA polymerase II transcription subunit 15"
					},
					{
						"name":"117209950 mediator of RNA polymerase II transcription subunit 16 isoform X1\tK15159 MED16; mediator of RNA polymerase II transcription subunit 16"
					}
					]
				},
				{
					"name":"CDK-module",
					"children":[
					{
						"name":"117210421 cyclin-C\tK15161 CCNC; cyclin-C"
					},
					{
						"name":"117204906 mediator of RNA polymerase II transcription subunit 12 isoform X1\tK15162 MED12; mediator of RNA polymerase II transcription subunit 12"
					},
					{
						"name":"117212119 mediator of RNA polymerase II transcription subunit 13 isoform X1\tK15164 MED13; mediator of RNA polymerase II transcription subunit 13"
					}
					]
				},
				{
					"name":"Other mediators",
					"children":[
					{
						"name":"117210324 mediator of RNA polymerase II transcription subunit 23\tK15166 MED23; mediator of RNA polymerase II transcription subunit 23"
					},
					{
						"name":"117206381 mediator of RNA polymerase II transcription subunit 24 isoform X1\tK15167 MED24; mediator of RNA polymerase II transcription subunit 24"
					},
					{
						"name":"117207452 mediator of RNA polymerase II transcription subunit 25-like isoform X1\tK15168 MED25; mediator of RNA polymerase II transcription subunit 25"
					},
					{
						"name":"117216989 mediator of RNA polymerase II transcription subunit 26 isoform X1\tK15169 MED26; mediator of RNA polymerase II transcription subunit 26"
					},
					{
						"name":"117209733 mediator of RNA polymerase II transcription subunit 27 isoform X1\tK15170 MED27; mediator of RNA polymerase II transcription subunit 27"
					}
					]
				}
				]
			},
			{
				"name":"Coactivators",
				"children":[
				{
					"name":"SAGA\/TFTC\/STAGA complex",
					"children":[
					{
						"name":"117212636 histone acetyltransferase KAT2A\tK06062 PCAF; histone acetyltransferase [EC:2.3.1.48]"
					},
					{
						"name":"117206364 transformation\/transcription domain-associated protein\tK08874 TRRAP; transformation\/transcription domain-associated protein"
					},
					{
						"name":"117205558 transcription initiation protein SPT3 homolog isoform X1\tK11313 SUPT3H; transcription initiation protein SPT3"
					},
					{
						"name":"117206354 transcriptional adapter 2-alpha-like isoform X1\tK11314 TADA2A; transcriptional adapter 2-alpha"
					},
					{
						"name":"117214506 transcriptional adapter 3-A\tK11315 TADA3; transcriptional adapter 3"
					},
					{
						"name":"117216195 transcriptional adapter 1-like isoform X1\tK11317 TADA1; transcriptional adapter 1"
					},
					{
						"name":"117207324 transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"117204350 transcription initiation factor TFIID subunit 4 isoform X1\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"117213978 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"117215738 TAF5-like RNA polymerase II p300\/CBP-associated factor-associated factor 65 kDa subunit 5L isoform X1\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"117207082 uncharacterized protein LOC117207082\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"117211324 transcription initiation factor TFIID subunit 6-like\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"117206976 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"117209484 transcription initiation factor TFIID subunit 9-like\tK03133 TAF9B; transcription initiation factor TFIID subunit 9B"
					},
					{
						"name":"117209648 transcription initiation factor TFIID subunit 9-like\tK03133 TAF9B; transcription initiation factor TFIID subunit 9B"
					},
					{
						"name":"117217007 transcription initiation factor TFIID subunit 10-like\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"117208817 transcription initiation factor TFIID subunit 12b isoform X1\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"117205061 ataxin-7-like protein 3\tK11363 ATXN7L; SAGA-associated factor 11"
					},
					{
						"name":"117211280 SAGA-associated factor 29\tK11364 SGF29; SAGA-associated factor 29"
					},
					{
						"name":"117214851 uncharacterized protein LOC117214851 isoform X1\tK11316 SUPT7L; STAGA complex 65 subunit gamma"
					},
					{
						"name":"117206555 ataxin-7-like protein 1 isoform X1\tK11318 ATXN7; ataxin-7"
					},
					{
						"name":"117206724 chromodomain-helicase-DNA-binding protein 1 isoform X1\tK11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"117205065 transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"117211699 ubiquitin carboxyl-terminal hydrolase 22\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
					},
					{
						"name":"117212701 splicing factor 3B subunit 3\tK12830 SF3B3; splicing factor 3B subunit 3"
					}
					]
				},
				{
					"name":"BAF\/PBAF complex",
					"children":[
					{
						"name":"117204805 ATP-dependent helicase brm-like\tK11647 SMARCA2_4; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2\/4 [EC:5.6.2.-]"
					},
					{
						"name":"117215385 ATP-dependent helicase brm-like isoform X1\tK11647 SMARCA2_4; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2\/4 [EC:5.6.2.-]"
					},
					{
						"name":"117210418 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"117209770 SWI\/SNF complex subunit SMARCC2 isoform X1\tK11649 SMARCC; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C"
					},
					{
						"name":"117214171 brahma-associated protein of 60 kDa isoform X1\tK11650 SMARCD; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D"
					},
					{
						"name":"117210358 bromodomain-containing protein 4-like\tK11651 SMARCE1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1"
					},
					{
						"name":"117207033 actin, clone 205-like\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117207034 actin, clone 205-like\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117207035 actin, muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117210151 actin-5C\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117212641 actin, clone 403-like\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"117206581 actin-like protein 6B\tK11652 ACTL6B; actin-like protein 6B"
					},
					{
						"name":"117206805 actin-like protein 6B\tK11652 ACTL6B; actin-like protein 6B"
					},
					{
						"name":"117212206 trithorax group protein osa isoform X1\tK11653 ARID1; AT-rich interactive domain-containing protein 1"
					},
					{
						"name":"117211867 AT-rich interactive domain-containing protein 2-like\tK11765 ARID2; AT-rich interactive domain-containing protein 2"
					},
					{
						"name":"117214690 LOW QUALITY PROTEIN: protein polybromo-1\tK11757 PBRM1; protein polybromo-1"
					}
					]
				},
				{
					"name":"SWI\/SNF complex",
					"children":[
					{
						"name":"117210418 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					}
					]
				},
				{
					"name":"RSC complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"117204120 activated RNA polymerase II transcriptional coactivator p15\tK25815 SUB1; activated RNA polymerase II transcriptional coactivator p15"
					},
					{
						"name":"117208136 cell division cycle and apoptosis regulator protein 1-like\tK25827 CCAR1; cell division cycle and apoptosis regulator protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"117212965 transcription elongation factor S-II isoform X1\tK03145 TFIIS; transcription elongation factor S-II"
					},
					{
						"name":"117207005 transcription elongation factor SPT4-A\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"117216243 transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					},
					{
						"name":"117206279 transcription elongation factor SPT6-like isoform X1\tK11292 SUPT6H; transcription elongation factor SPT6"
					},
					{
						"name":"117214062 transcription elongation factor SPT6 isoform X1\tK11292 SUPT6H; transcription elongation factor SPT6"
					}
					]
				},
				{
					"name":"Transcription termination factor",
					"children":[
					{
						"name":"117214063 transcription termination factor 2\tK15173 TTF2; transcription termination factor 2 [EC:5.6.2.-]"
					},
					{
						"name":"117206505 uncharacterized protein LOC117206505 isoform X1\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					},
					{
						"name":"117210402 cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"117206335 cleavage and polyadenylation specificity factor 73\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"117205297 cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"117207895 serine\/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"117212235 serine\/threonine-protein phosphatase alpha-2 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"117211344 symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"117210495 RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"117213156 5'-3' exoribonuclease 2 homolog\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"117211582 uncharacterized protein LOC117211582\tK14845 RAI1; RAT1-interacting protein"
					},
					{
						"name":"117207504 regulation of nuclear pre-mRNA domain-containing protein 1B isoform X1\tK15559 RTT103; regulator of Ty1 transposition protein 103"
					},
					{
						"name":"117210834 hrp65 protein-like\tK13219 SFPQ; splicing factor, proline- and glutamine-rich"
					},
					{
						"name":"117210912 hrp65 protein-like\tK13219 SFPQ; splicing factor, proline- and glutamine-rich"
					},
					{
						"name":"117204916 SR-related and CTD-associated factor 4\tK13191 RBM16; RNA-binding protein 16"
					},
					{
						"name":"117216567 uncharacterized protein LOC117216567\tK10706 SETX; ATP-dependent RNA\/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"117204871 putative peptidyl-prolyl cis-trans isomerase dodo\tK09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"
					}
					]
				},
				{
					"name":"PAF1 complex",
					"children":[
					{
						"name":"117212276 RNA polymerase II-associated factor 1 homolog isoform X1\tK15174 PAF1; RNA polymerase II-associated factor 1"
					},
					{
						"name":"117214375 parafibromin\tK15175 CDC73; parafibromin"
					},
					{
						"name":"117206595 RNA polymerase-associated protein CTR9 homolog\tK15176 CTR9; RNA polymerase-associated protein CTR9"
					},
					{
						"name":"117215752 another transcription unit protein\tK15177 LEO1; RNA polymerase-associated protein LEO1"
					},
					{
						"name":"117206540 RNA polymerase-associated protein Rtf1-like\tK15178 RTF1; RNA polymerase-associated protein RTF1"
					}
					]
				},
				{
					"name":"NELF complex",
					"children":[
					{
						"name":"117205767 negative elongation factor A isoform X1\tK15179 WHSC2; negative elongation factor A"
					},
					{
						"name":"117204325 negative elongation factor B\tK15180 COBRA1; negative elongation factor B"
					},
					{
						"name":"117213210 negative elongation factor D isoform X1\tK15181 TH1L; negative elongation factor C\/D"
					},
					{
						"name":"117211704 negative elongation factor E\tK15182 RDBP; negative elongation factor E"
					}
					]
				},
				{
					"name":"Super elongation complex (SEC)",
					"children":[
					{
						"name":"117214668 RNA polymerase II elongation factor Ell\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"117214050 ell-associated factor Eaf\tK15186 EAF; ELL-associated factor"
					},
					{
						"name":"117216357 protein AF-9 isoform X1\tK15187 MLLT1_3; YEATS domain-containing protein 1\/3"
					},
					{
						"name":"117217323 cyclin-T-like isoform X1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"117210327 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"Little elongation complex (LEC)",
					"children":[
					{
						"name":"117214668 RNA polymerase II elongation factor Ell\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"117207325 uncharacterized protein LOC117207325\tK26144 ICE2; little elongation complex subunit 2"
					}
					]
				},
				{
					"name":"Brd4\/P-TEFb complex",
					"children":[
					{
						"name":"117217323 cyclin-T-like isoform X1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"117210327 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"BUR kinase complex"
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"7SK RNP complex",
					"children":[
					{
						"name":"117213087 protein HEXIM1\tK15189 HEXIM1_2; protein HEXIM1\/2"
					},
					{
						"name":"117211316 probable RNA methyltransferase bin3\tK15190 MEPCE; 7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-]"
					},
					{
						"name":"117211154 la-related protein 7\tK15191 LARP7; La-related protein 7"
					},
					{
						"name":"117217323 cyclin-T-like isoform X1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"117210327 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"DBIRD complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"117211242 TATA-binding protein-associated factor 172 isoform X1\tK15192 BTAF1; TATA-binding protein-associated factor [EC:5.6.2.-]"
					},
					{
						"name":"117216906 protein Dr1 isoform X1\tK21751 DR1; down-regulator of transcription 1"
					},
					{
						"name":"117206632 dr1-associated corepressor isoform X1\tK21752 DRAP1; Dr1-associated corepressor"
					},
					{
						"name":"117208180 protein SPT2 homolog\tK15193 SPTY2D1; protein SPT2"
					},
					{
						"name":"117206825 AF4\/FMR2 family member 4 isoform X1\tK15194 AFF2; AF4\/FMR2 family member 2"
					},
					{
						"name":"117210971 RNA polymerase II subunit A C-terminal domain phosphatase\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"117210132 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X1\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"117207659 IWS1-like protein isoform X1\tK17498 SPN1; transcription factor SPN1"
					},
					{
						"name":"117210212 RNA polymerase II-associated protein 1\tK20826 RPAP1; RNA polymerase II-associated protein 1"
					},
					{
						"name":"117204565 putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 isoform X1\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
					},
					{
						"name":"117208002 RNA polymerase II-associated protein 3 isoform X1\tK23002 RPAP3; RNA polymerase II-associated protein 3"
					},
					{
						"name":"117205028 cyclin-K\tK23326 CCNK; cyclin K"
					},
					{
						"name":"117204631 GPN-loop GTPase 1\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"117204635 GPN-loop GTPase 3\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"117215065 GPN-loop GTPase 2 isoform X1\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"117206284 probable RNA polymerase II nuclear localization protein SLC7A6OS\tK28237 SLC7A6OS; RNA polymerase II nuclear localization protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase III system",
			"children":[
			{
				"name":"RNA polymerase III",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"117206927 DNA-directed RNA polymerase III subunit RPC1\tK03018 RPC1; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]"
					},
					{
						"name":"117209390 DNA-directed RNA polymerase III subunit RPC2 isoform X1\tK03021 RPC2; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]"
					},
					{
						"name":"117210128 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"117214441 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol III specific subunits",
					"children":[
					{
						"name":"117213565 DNA-directed RNA polymerase III subunit RPC3\tK03023 RPC3; DNA-directed RNA polymerase III subunit RPC3"
					},
					{
						"name":"117214185 DNA-directed RNA polymerase III subunit RPC4\tK03026 RPC4; DNA-directed RNA polymerase III subunit RPC4"
					},
					{
						"name":"117217228 DNA-directed RNA polymerase III subunit RPC5\tK14721 RPC5; DNA-directed RNA polymerase III subunit RPC5"
					},
					{
						"name":"117213078 probable DNA-directed RNA polymerase III subunit RPC6\tK03025 RPC6; DNA-directed RNA polymerase III subunit RPC6"
					},
					{
						"name":"117213092 probable DNA-directed RNA polymerase III subunit RPC6\tK03025 RPC6; DNA-directed RNA polymerase III subunit RPC6"
					},
					{
						"name":"117207317 DNA-directed RNA polymerase III subunit RPC7-like\tK03024 RPC7; DNA-directed RNA polymerase III subunit RPC7"
					},
					{
						"name":"117211714 DNA-directed RNA polymerase III subunit RPC8\tK03022 RPC8; DNA-directed RNA polymerase III subunit RPC8"
					},
					{
						"name":"117209213 DNA-directed RNA polymerase III subunit RPC9\tK25304 RPC9; DNA-directed RNA polymerase III subunit RPC9"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"117217252 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"117205960 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"117205462 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"117213502 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"117209007 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIIA",
					"children":[
					{
						"name":"117214849 zinc finger protein 888-like\tK09191 GTF3A; general transcription factor IIIA"
					}
					]
				},
				{
					"name":"TFIIIB",
					"children":[
					{
						"name":"117204087 TATA box-binding protein-like protein 1\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117205487 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117212013 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117210121 transcription factor IIIB 90 kDa subunit isoform X1\tK15196 BRF1; transcription factor IIIB 90 kDa subunit"
					},
					{
						"name":"117207310 transcription factor TFIIIB component B''\tK15198 BDP1; transcription factor TFIIIB component B''"
					}
					]
				},
				{
					"name":"TFIIIC",
					"children":[
					{
						"name":"117208145 general transcription factor 3C polypeptide 1\tK15199 GTF3C1; general transcription factor 3C polypeptide 1"
					},
					{
						"name":"117210754 uncharacterized protein LOC117210754 isoform X1\tK15200 GTF3C2; general transcription factor 3C polypeptide 2"
					},
					{
						"name":"117205416 general transcription factor 3C polypeptide 3\tK15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)"
					},
					{
						"name":"117217261 uncharacterized protein LOC117217261\tK11310 GTF3C4; general transcription factor 3C polypeptide 4 [EC:2.3.1.48]"
					},
					{
						"name":"117212278 general transcription factor 3C polypeptide 5\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					},
					{
						"name":"117208121 uncharacterized protein LOC117208121\tK15203 GTF3C6; general transcription factor 3C polypeptide 6"
					}
					]
				},
				{
					"name":"TFIIIC, fungi type",
					"children":[
					{
						"name":"117212278 general transcription factor 3C polypeptide 5\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					},
					{
						"name":"117205416 general transcription factor 3C polypeptide 3\tK15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"snRNA-activating protein complex (SNAPc)",
					"children":[
					{
						"name":"117204523 snRNA-activating protein complex subunit 1 isoform X1\tK15208 SNAPC1; snRNA-activating protein complex subunit 1"
					},
					{
						"name":"117214452 snRNA-activating protein complex subunit 3\tK15210 SNAPC3; snRNA-activating protein complex subunit 3"
					}
					]
				},
				{
					"name":"Octamer transcription factors",
					"children":[
					{
						"name":"117212494 POU domain, class 2, transcription factor 1-like isoform X1\tK09364 POU2F; POU domain transcription factor, class 2"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"117210476 zinc finger protein 76-like isoform X1\tK20828 ZNF143_76; zinc finger protein 143\/76"
					},
					{
						"name":"117211382 repressor of RNA polymerase III transcription MAF1 homolog isoform X1\tK25817 MAF1; repressor of RNA polymerase III transcription MAF1"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase I system",
			"children":[
			{
				"name":"RNA polymerase I",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"117213760 DNA-directed RNA polymerase I subunit RPA1\tK02999 RPA1; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]"
					},
					{
						"name":"117204215 DNA-directed RNA polymerase I subunit RPA2 isoform X1\tK03002 RPA2; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]"
					},
					{
						"name":"117210128 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"117214441 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol I specific subunits",
					"children":[
					{
						"name":"117210024 uncharacterized protein LOC117210024\tK03005 RPA49; DNA-directed RNA polymerase I subunit RPA49"
					},
					{
						"name":"117212041 LOW QUALITY PROTEIN: uncharacterized protein MAL13P1.304\tK03004 RPA43; DNA-directed RNA polymerase I subunit RPA43"
					},
					{
						"name":"117216801 DNA-directed RNA polymerase I subunit RPA12\tK03000 RPA12; DNA-directed RNA polymerase I subunit RPA12"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"117217252 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"117205960 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"117205462 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"117213502 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"117209007 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"SL1\/TIF-1B",
					"children":[
					{
						"name":"117204087 TATA box-binding protein-like protein 1\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117205487 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117212013 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"117209908 TATA box-binding protein-associated factor RNA polymerase I subunit B isoform X1\tK15213 TAF1B; TATA box-binding protein-associated factor RNA polymerase I subunit B"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"UBF"
				},
				{
					"name":"Transcription initiation factors",
					"children":[
					{
						"name":"117210425 RNA polymerase I-specific transcription initiation factor RRN3\tK15216 RRN3; RNA polymerase I-specific transcription initiation factor RRN3"
					},
					{
						"name":"117209918 upstream activation factor subunit spp27\tK15223 UAF30; upstream activation factor subunit UAF30"
					}
					]
				},
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"117207005 transcription elongation factor SPT4-A\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"117216243 transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"NoRC (nucleolar remodeling complex)",
					"children":[
					{
						"name":"117210318 chromatin-remodeling complex ATPase chain Iswi\tK11654 SMARCA5; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"Transcription termination factors"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"117214155 nucleolar protein dao-5 isoform X1\tK25818 NOLC1; nucleolar and coiled-body phosphoprotein 1"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				},
				{
					"name":"Sigma factors"
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"RNA polymerase-associated proteins"
				},
				{
					"name":"Transcription elongation factors"
				},
				{
					"name":"Transcription termination factor"
				}
				]
			}
			]
		},
		{
			"name":"Archaeal type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFB",
					"children":[
					{
						"name":"117209032 transcription initiation factor IIB isoform X1\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFE",
					"children":[
					{
						"name":"117209581 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					}
					]
				},
				{
					"name":"TFS"
				}
				]
			}
			]
		}
		]
	}
	]
}
