{
	"name":"bcj04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"BCAL2442 htpG; chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"BCAL2179 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"BCAL3388 gapA; glyceraldehyde 3-phosphate dehydrogenase 1\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"BCAL2841 pgk; phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"BCAL2840 pykA; putative pyruvate kinase II protein\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"BCAL2152 ppiA; peptidyl-prolyl cis-trans isomerase A precursor\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
			},
			{
				"name":"BCAM2325 putative dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"BCAL3146 groEL1; 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAM0548 groL2; 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAS0637 groL3; 60 kDa chaperonin 3\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAL3270 dnaK; putative DnaK chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"BCAL1990 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"BCAM2586 putative lactonase\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
			},
			{
				"name":"BCAL2063 guaB; inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"BCAL0219 tufA1; elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"BCAL0232 tuf; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"BCAL0322 conserved hypothetical protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			},
			{
				"name":"BCAM2642 conserved hypothetical protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells"
		},
		{
			"name":"Exosomal proteins of hepatic cells",
			"children":[
			{
				"name":"BCAL0622 putative sodium bile acid symporter family protein\tK14347 SLC10A7; solute carrier family 10 (sodium\/bile acid cotransporter), member 7"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"BCAL1541 putative acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAL2772 putative AMP-binding enzyme\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAL3474 fadD; long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAS0616 acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAL2786 putative selenium-binding protein\tK17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"BCAL3146 groEL1; 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAM0548 groL2; 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAS0637 groL3; 60 kDa chaperonin 3\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAL0832 phaA; putative poly-beta-hydroxy-butyrate storage protein\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"BCAL1862 phbA; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"BCAS0608 bktB; beta-ketothiolase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"BCAS0737 putative acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"BCAL0145 ahcY; adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"BCAL2762 adk; putative adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"BCAL0820 putative adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"BCAL2638 argH; argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"BCAM0746 argG; argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"BCAM0976 putative amidinotransferase\tK01482 DDAH; dimethylargininase [EC:3.5.3.18]"
			},
			{
				"name":"BCAS0731 dhT; D-hydantoinase\tK01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]"
			},
			{
				"name":"BCAL3183 putative hydrolase\tK01555 FAH; fumarylacetoacetase [EC:3.7.1.2]"
			},
			{
				"name":"BCAL2994 fbp; fructose-1,6-bisphosphatase, chromosomal\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
			},
			{
				"name":"BCAL0925 glpK; putative glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"BCAM1104 putative glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"BCAL0600 putative glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"BCAL2224 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"BCAL2238 putative glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"BCAM2094 puuA; putative gamma-glutamylputrescine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"BCAL1990 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"BCAL0264 hemB; delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"BCAL0207 hppD; 4-hydroxyphenylpyruvic acid dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"BCAM1522 putative dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"BCAL0009 pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"BCAM0389 putative alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"BCAM0390 putative alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"BCAL0460 D-isomer specific 2-hydroxyacid dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"BCAM1715 putative D-isomer specific 2-hydroxyacid dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"BCAM2587 serA; putative D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"BCAL3336 purH; bifunctional purine biosynthesis protein\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			},
			{
				"name":"BCAL2920 metallo peptidase, subfamily M48A\tK06013 STE24; STE24 endopeptidase [EC:3.4.24.84]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"BCAL1541 putative acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAL2772 putative AMP-binding enzyme\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAL3474 fadD; long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAS0616 acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"BCAL1215 lpdV; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"BCAL1517 odhL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"BCAL2207 putative dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"BCAL2934 etfA; electron transfer flavoprotein alpha-subunit\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"BCAM1606 electron transfer flavoprotein, alpha subunit\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"BCAL3359 putative glutamate dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
			},
			{
				"name":"BCAL3042 zwf; glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"BCAM2600 zwf; putative glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"BCAL2063 guaB; inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"BCAL3270 dnaK; putative DnaK chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"BCAL3146 groEL1; 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAM0548 groL2; 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAS0637 groL3; 60 kDa chaperonin 3\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAL0219 tufA1; elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"BCAL0232 tuf; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"BCAL3146 groEL1; 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAM0548 groL2; 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAS0637 groL3; 60 kDa chaperonin 3\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAL1990 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"BCAL3042 zwf; glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"BCAM2600 zwf; putative glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"BCAL3270 dnaK; putative DnaK chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"BCAL2346 tpiA; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"BCAL0219 tufA1; elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"BCAL0232 tuf; elongation factor Tu (EF-Tu)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"BCAL3146 groEL1; 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAM0548 groL2; 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAS0637 groL3; 60 kDa chaperonin 3\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"BCAL3042 zwf; glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"BCAM2600 zwf; putative glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"BCAL0739 gpmA; phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"BCAL2346 tpiA; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"BCAL0739 gpmA; phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"BCAL2346 tpiA; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}
