{
	"name":"bod03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"106621332 Rnmt; mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]"
					},
					{
						"name":"106616714 mRNA-cap; mRNA-capping enzyme\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]"
					},
					{
						"name":"106626982 Cdk7; cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"106623915 Cmtr1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					},
					{
						"name":"106621703 aft; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]"
					},
					{
						"name":"106620488 RNA guanine-N7 methyltransferase activating subunit\tK18708 FAM103A1; RNMT-activating mini protein"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"106619441 Cbp80; nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"106615947 Cbp20; nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"106621868 Cpsf5; cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"106615505 Cpsf6; cleavage and polyadenylation specificity factor subunit 6 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"106620353 cbc; protein CLP1 homolog\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"106618746 Pcf11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X2\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"106616478 Cpsf160; cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"106618255 Cpsf100; probable cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"106620049 Cpsf73; cleavage and polyadenylation specificity factor 73\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"106617546 Clp; cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"106621656 Fip1; pre-mRNA 3'-end-processing factor FIP1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1"
					},
					{
						"name":"106618099 Wdr33; pre-mRNA 3' end processing protein WDR33\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"106624249 Wdr82; WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"106616813 Pp1alpha-96A; serine\/threonine-protein phosphatase alpha-1 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106619108 Pp1-87B; serine\/threonine-protein phosphatase alpha-2 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106624850 flw; serine\/threonine-protein phosphatase beta isoform isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106619706 Ssu72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 isoform X2\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"106619093 CstF50; cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"106620050 CstF64; cleavage stimulation factor subunit 2\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"106619619 su(f); protein suppressor of forked\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"106627750 Sym; symplekin\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"106615383 SmB; small nuclear ribonucleoprotein-associated protein B\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"106619174 SmD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"106619340 SmE; probable small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"106622476 SmF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"106619196 SNRPG; probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"106614484 Lsm10; U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10"
					},
					{
						"name":"106618255 Cpsf100; probable cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"106620049 Cpsf73; cleavage and polyadenylation specificity factor 73\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"106620050 CstF64; cleavage stimulation factor subunit 2\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"106627750 Sym; symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"106621251 Slbp; histone RNA hairpin-binding protein isoform X1\tK18710 SLBP; histone RNA hairpin-binding protein"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"106625055 spt4; transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"106626899 Spt5; transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"106616450 Mettl3; N6-adenosine-methyltransferase MT-A70-like protein\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]"
					},
					{
						"name":"106615619 Mettl14; N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"138855624 Mettl4; N(6)-adenine-specific methyltransferase METTL4\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"106621395 U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"106616477 fl(2)d; pre-mRNA-splicing regulator female-lethal(2)D\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"106624361 vir; protein virilizer isoform X1\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"106618911 nito; RNA-binding protein spenito isoform X2\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"106627184 Hakai; E3 ubiquitin-protein ligase Hakai\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"106614183 poly(A) polymerase type 3\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"106621940 swm; zinc finger protein swm\tK13192 RBM26; RNA-binding protein 26"
					},
					{
						"name":"106626889 TBPH; TAR DNA-binding protein 43 isoform X1\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"106622147 kin17; DNA\/RNA-binding protein KIN17\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"106621689 methyltransferase-like protein 22\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"106623366 terminal nucleotidyltransferase 5C isoform X3\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"106614372 Nab2; zinc finger CCCH domain-containing protein 13\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				},
				{
					"name":"106618657 Ars2; serrate RNA effector molecule homolog isoform X1\tK27103 SRRT; serrate RNA effector molecule"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"106625701 tsu; RNA-binding protein 8A\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"106626841 mago; protein mago nashi\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"106622910 Ref1; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"106616769 Hel25E; ATP-dependent RNA helicase WM6\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"106622107 ATP-dependent RNA helicase WM6\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"106617787 eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"106616550 coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"106619587 btz; protein CASC3\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"106622897 Bin1; histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"106615968 RnpS1; RNA-binding protein with serine-rich domain 1-B\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"106616974 Srrm1; serine\/arginine repetitive matrix protein 1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"106617255 Hpr1; THO complex subunit 1 isoform X1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"106616761 tho2; THO complex subunit 2\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"106623012 tex; THO complex subunit 3\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"106622910 Ref1; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"106617683 thoc5; THO complex subunit 5\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"106620698 thoc6; THO complex subunit 6\tK13175 THOC6; THO complex subunit 6"
					},
					{
						"name":"106621707 thoc7; THO complex protein 7\tK13176 THOC7; THO complex subunit 7"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"106625852 PCID2; PCI domain-containing protein 2 homolog\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"106618011 Sem1; probable 26S proteasome complex subunit sem1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"106627704 e(y)2b; enhancer of yellow 2 transcription factor\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"106617847 Mgtor; nucleoprotein TPR\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"106616475 Rae1; protein Rae1\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"106615119 Sec13; protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"106618767 Nup37; nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"106626882 Nup75; nuclear pore complex protein Nup75\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"106614806 Nup43; nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43"
					},
					{
						"name":"106627836 Nup50; nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"106624055 Nup54; probable nucleoporin Nup54 isoform X1\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"106619124 Nup62; nuclear pore glycoprotein p62\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"106615408 mbo; nuclear pore complex protein Nup88\tK14318 NUP88; nuclear pore complex protein Nup88"
					},
					{
						"name":"106621482 Nup98-96; nuclear pore complex protein Nup98-Nup96\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"106622491 Nup107; nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"106616057 Nup133; nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"106621208 Nup188; nucleoporin Nup188\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"106627014 Nup153; nuclear pore complex protein Nup153 isoform X2\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"106617502 Nup154; nuclear pore complex protein Nup154\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"106615787 Nup160; nuclear pore complex protein Nup160 homolog\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"106623103 Nup35; nucleoporin Nup35\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"106621419 Nup205; nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"106624911 Gp210; nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"118683212 Nup214; nuclear pore complex protein Nup214 isoform X1\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"106621465 ice-structuring glycoprotein\tK14316 POM121; nuclear pore complex protein Nup121"
					},
					{
						"name":"106615971 Nup58; nuclear pore complex protein Nup58\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"106618001 uncharacterized protein\tK14321 NUPL2; nucleoporin-like protein 2"
					},
					{
						"name":"106621237 Ndc1; nucleoporin Ndc1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"106619984 nucleoporin seh1\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"106619995 nucleoporin seh1\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"106625170 Aladin; aladin\tK14320 AAAS; aladin"
					},
					{
						"name":"106614202 Gle1; mRNA export factor Gle1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"106617194 sbr; nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"106618318 Nxt1; NTF2-related export protein\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"106617213 Ran; GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"106622326 Mapmodulin; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"106621269 Rbp9; ELAV-like protein 2 isoform X2\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"106623074 elav; protein elav isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"106624644 fne; ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"106616775 Faf2; FAS-associated factor 2\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"106627869 TER94; transitional endoplasmic reticulum ATPase TER94\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"106624255 emb; exportin-1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"118681288 Ranbp16; ran-binding protein 16 isoform X2\tK18460 XPO7; exportin-7"
					},
					{
						"name":"106615440 RanGAP; ran GTPase-activating protein\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"106623108 Ntf-2; probable nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"106615136 eIF4EHP; eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"106616283 eukaryotic translation initiation factor 4E1 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"106623530 eIF4A; eukaryotic initiation factor 4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"106619250 eIF4G1; eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"106620381 eIF4B; eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"106617480 eIF4H1; eukaryotic translation initiation factor 4H isoform X2\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"106614984 Thor; eukaryotic translation initiation factor 4E-binding protein\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2"
					},
					{
						"name":"106620758 angel; protein angel\tK18729 ANGEL; protein angel"
					},
					{
						"name":"106617308 Fmr1; fragile X messenger ribonucleoprotein 1 homolog isoform X3\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"106623006 Cyfip; cytoplasmic FMR1-interacting protein\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"106615117 orb; cytoplasmic polyadenylation element-binding protein isoform X2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"106627745 bel; ATP-dependent RNA helicase bel\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"106620730 Gyf; GIGYF family protein Gyf isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"106618655 pAbp; polyadenylate-binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"106614207 Paip1; polyadenylate-binding protein-interacting protein 1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"106615145 Paip2; polyadenylate-binding protein-interacting protein 2 isoform X2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"106616142 tst; superkiller complex protein 2\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"106620702 Deaf1; deformed epidermal autoregulatory factor 1\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"106614649 MCTS1; malignant T-cell-amplified sequence 1 homolog\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"106621510 DENR; density-regulated protein homolog isoform X2\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex"
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"106619067 Pym; partner of Y14 and mago\tK14294 WIBG; partner of Y14 and mago"
					},
					{
						"name":"106614603 heterogeneous nuclear ribonucleoprotein 87F isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"106614794 heterogeneous nuclear ribonucleoprotein A1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"106614793 Rbp4; ribonucleoprotein RB97D isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"106617407 Hrb27C; heterogeneous nuclear ribonucleoprotein 27C\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"106619204 RNA-binding protein Musashi homolog Rbp6 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"106620186 Rb97D; ribonucleoprotein RB97D\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"106624164 msi; uncharacterized protein msi isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"106619074 HBS1; protein HBS1\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"106623690 pelo; protein pelota\tK06965 PELO; protein pelota"
					},
					{
						"name":"106620783 Pabp2; polyadenylate-binding protein 2 isoform X1\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"106621497 Dbp80; DEAD-box helicase Dbp80 isoform X1\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"106617004 fand; pre-mRNA-splicing factor syf1 homolog\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"106618083 SAP domain-containing ribonucleoprotein\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"106625429 Rcc1; regulator of chromosome condensation\tK11493 RCC1; regulator of chromosome condensation"
					},
					{
						"name":"106618449 Achl; uncharacterized protein Achl\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"106620746 Pur-alpha; transcriptional activator protein Pur-alpha isoform X1\tK21772 PURA; transcriptional activator protein Pur-alpha"
					},
					{
						"name":"106615759 polymerase delta-interacting protein 3\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"106623770 leukocyte receptor cluster member 8 homolog\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"106622152 eRF1; eukaryotic peptide chain release factor subunit 1 isoform X1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"106615291 eRF3; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"106627047 Upf1; regulator of nonsense transcripts 1 homolog\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"106618379 Upf2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"106619983 Upf3; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"106614976 mts; serine\/threonine-protein phosphatase PP2A\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106625330 Pp2A-29B; serine\/threonine-protein phosphatase PP2A 65 kDa regulatory subunit isoform X1\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"106618955 tws; protein phosphatase PP2A 55 kDa regulatory subunit isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"106623437 serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"106627712 serine-rich adhesin for platelets\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"106615949 wrd; uncharacterized protein wrd isoform X2\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"106619585 wdb; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"106616084 nonC; serine\/threonine-protein kinase Smg1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"106625272 Smg5; nonsense-mediated mRNA decay factor SMG5\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"106619060 Smg6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"106624612 nonsense-mediated mRNA decay factor SMG8\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"106619315 protein SMG9\tK18735 SMG9; protein SMG9"
					},
					{
						"name":"106620730 Gyf; GIGYF family protein Gyf isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"106615459 Sbp2; selenocysteine insertion sequence-binding protein 2\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2"
					},
					{
						"name":"106621570 probable ATP-dependent RNA helicase DHX34\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]"
					},
					{
						"name":"106625593 GTPBP1; GTP-binding protein 1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"106616713 peng; protein penguin\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"106618906 didum; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"106615648 BicD; protein bicaudal D\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"106627779 egl; uncharacterized protein MAL13P1.304\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"106615930 Act88F; actin, indirect flight muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106617766 Act87E; actin-3, muscle-specific\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106619748 actin-5, muscle-specific\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106623726 Act57B; actin-2, muscle-specific\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106623778 Act5C; actin, cytoplasmic A3a\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"106627914 Myc; myc protein\tK04377 MYC; Myc proto-oncogene protein"
					},
					{
						"name":"106619544 T-box-containing protein TBX6L\tK10180 TBX6; T-box protein 6"
					},
					{
						"name":"106619799 T-box transcription factor TBX6 isoform X1\tK10180 TBX6; T-box protein 6"
					},
					{
						"name":"106616165 nanos; protein nanos\tK18741 NANOS1; protein nanos 1"
					},
					{
						"name":"106622417 osk; maternal effect protein oskar isoform X2\tK18742 OSK; maternal effect protein oskar"
					},
					{
						"name":"106617482 fs(1)K10; DNA-binding protein K10\tK02524 K10; DNA binding protein (fs(1)K10, female sterile(1)K10)"
					},
					{
						"name":"106615087 grk; protein gurken\tK02447 GRK; protein gruken"
					},
					{
						"name":"106614329 E(spl)mbeta-HLH; enhancer of split mbeta protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106614333 E(spl)m3-HLH; enhancer of split m3 protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106614335 enhancer of split m8 protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106614337 enhancer of split m5 protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106614339 E(spl)mgamma-HLH; enhancer of split mgamma protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106614341 E(spl)m7-HLH; enhancer of split m7 protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106614345 E(spl)mdelta-HLH; enhancer of split mdelta protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106615507 hry; protein hairy\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106616005 Hesr; enhancer of split mgamma protein\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"106618676 dpn; protein deadpan isoform X1\tK09090 HESN; hairy and enhancer of split, invertebrate"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"106618313 Psi; far upstream element-binding protein 3\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"106619094 eEF1alpha2; elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"106619814 eEF1alpha1; elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"106627763 eEF1gamma; elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"106619717 drongo; arf-GAP domain and FG repeat-containing protein 1 isoform X5\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"106627316 stau; maternal effect protein staufen\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"106618709 heph; polypyrimidine tract-binding protein 2 isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"106614795 sqd; RNA-binding protein squid isoform X1\tK03102 SQD; squid"
					},
					{
						"name":"106615117 orb; cytoplasmic polyadenylation element-binding protein isoform X2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"106617308 Fmr1; fragile X messenger ribonucleoprotein 1 homolog isoform X3\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"106623006 Cyfip; cytoplasmic FMR1-interacting protein\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"106619972 mub; poly(rC)-binding protein 2 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"106620426 Capr; caprin homolog\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"106624686 bru1; CUGBP Elav-like family member 2 isoform X1\tK02177 BRU; bruno"
					},
					{
						"name":"106627619 exu; maternal protein exuperantia\tK18745 EXU; maternal protein exuperantia"
					},
					{
						"name":"106617379 cup; protein cup\tK18746 CUP; protein cup"
					},
					{
						"name":"106618967 sxl; sex-lethal homolog\tK18747 SXL; protein sex-lethal"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"106621566 pcm; 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"106614169 AGO1; protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"106615136 eIF4EHP; eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"106616283 eukaryotic translation initiation factor 4E1 isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"106627047 Upf1; regulator of nonsense transcripts 1 homolog\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"106627745 bel; ATP-dependent RNA helicase bel\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"106620181 me31B; ATP-dependent RNA helicase me31b\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"106618826 tral; protein LSM14 homolog A isoform X1\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"106622531 jub; LIM domain-containing protein jub\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"106614110 transportin-1\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"106616084 nonC; serine\/threonine-protein kinase Smg1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"106625272 Smg5; nonsense-mediated mRNA decay factor SMG5\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"106619060 Smg6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"106624627 Tis11; protein TIS11\tK15308 TTP; tristetraprolin"
					},
					{
						"name":"106627969 lin-28; protein lin-28 homolog\tK18754 LIN28; protein lin-28"
					},
					{
						"name":"106624414 BicC; protein bicaudal C isoform X1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"106614603 heterogeneous nuclear ribonucleoprotein 87F isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"106614794 heterogeneous nuclear ribonucleoprotein A1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"106623618 Pka-C1; cAMP-dependent protein kinase catalytic subunit 1 isoform X2\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"106615131 larp; la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"106615955 Atx2; ataxin-2 homolog\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"106624830 DCP2; uncharacterized protein DCP2\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"106617560 DCP1; mRNA-decapping enzyme 1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"106614464 LSm1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"106615487 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"106617704 LSm3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"106623909 U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"106620621 U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"106619669 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"106625806 LSm7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"106615496 U6 snRNA-associated Sm-like protein LSm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"106617975 Klc; kinesin light chain isoform X2\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"106618906 didum; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"106620772 tubulin alpha-1 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"106621253 tubulin alpha-4 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"106627729 alphaTub84B; tubulin alpha-1 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"106615117 orb; cytoplasmic polyadenylation element-binding protein isoform X2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"106619834 gw; protein Gawky isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"106622561 Not1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"106622967 Rga; regulator of gene activity isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"106615868 Not3; CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"106622091 Cnot4; uncharacterized protein DDB_G0286591\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"106615190 twin; CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"106616378 Pop2; CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"106621954 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"106617600 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"106618601 Tob; protein Tob1 isoform X1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"106623604 Patr-1; uncharacterized protein Patr-1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"106621521 Edc3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"106615028 Ge-1; enhancer of mRNA-decapping protein 4 homolog isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"106618379 Upf2; regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"106619983 Upf3; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"106618905 wech; protein wech isoform X1\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"106623347 Polr2G; DNA-directed RNA polymerase II subunit RPB7 isoform X1\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"106623323 Ythdf; YTH domain-containing family protein isoform X1\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"106617164 trv; cytotoxic granule associated RNA binding protein TIA1 isoform X2\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"106617165 cytotoxic granule associated RNA binding protein TIA1 isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"106619591 Rox8; nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"106618655 pAbp; polyadenylate-binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"106627316 stau; maternal effect protein staufen\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"106617308 Fmr1; fragile X messenger ribonucleoprotein 1 homolog isoform X3\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"106614792 rin; ras GTPase-activating protein-binding protein 1\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"106621294 eIF2A; eukaryotic translation initiation factor 2A\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"106626836 eIF3b; eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"106623530 eIF4A; eukaryotic initiation factor 4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"106617787 eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"106620381 eIF4B; eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"106619250 eIF4G1; eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"106626994 S6kII; ribosomal protein S6 kinase 2 beta\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"106615605 Rack1; small ribosomal subunit protein RACK1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"106617194 sbr; nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"106615888 HDAC6; histone deacetylase 6 isoform X1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"106620710 Tdrd3; tudor domain-containing protein 3\tK18404 TDRD3; tudor domain-containing protein 3"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"106617560 DCP1; mRNA-decapping enzyme 1\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"106624830 DCP2; uncharacterized protein DCP2\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"106620181 me31B; ATP-dependent RNA helicase me31b\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"106621521 Edc3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"106615028 Ge-1; enhancer of mRNA-decapping protein 4 homolog isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"106623604 Patr-1; uncharacterized protein Patr-1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"106614464 LSm1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"106615487 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"106617704 LSm3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"106623909 U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"106620621 U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"106619669 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"106625806 LSm7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"106615496 U6 snRNA-associated Sm-like protein LSm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"106621566 pcm; 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"106617429 Rat1; 5'-3' exoribonuclease 2 homolog\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"106627741 Dcps; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"106616373 Helz; probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"106615801 Csl4; exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"106621233 Rrp4; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"106615025 Rrp40; exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"106615937 Ski6; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"106623541 Rrp46; exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"106617989 Mtr3; exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"106619618 Rrp42; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"106617966 exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"106616089 Rrp45; exosome complex component RRP45\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"106618353 Dis3; exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"106623421 Rrp6; exosome complex component 10 homolog\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"106615277 Mpp6; M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"106624233 Trf4-1; non-canonical poly(A) RNA polymerase protein Trf4-1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"106623662 Mtr4; exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"106616142 tst; superkiller complex protein 2\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"106625160 tetratricopeptide repeat protein 37\tK12600 SKI3; superkiller protein 3"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"106615190 twin; CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"106622561 Not1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"106622967 Rga; regulator of gene activity isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"106615868 Not3; CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"106622091 Cnot4; uncharacterized protein DDB_G0286591\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"106616378 Pop2; CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"106617479 Rcd-1; CCR4-NOT transcription complex subunit 9\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"106622627 Not10; CCR4-NOT transcription complex subunit 10 isoform X1\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"106621954 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"106617600 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"106622259 Rhau; ATP-dependent DNA\/RNA helicase DHX36 isoform X1\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"106618601 Tob; protein Tob1 isoform X1\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"106627741 Dcps; m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"118681290 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"106616373 Helz; probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"106614662 nuclear exosome regulator NRDE2\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"106619801 smg; protein Smaug isoform X1\tK27396 SMG; protein Smaug"
					},
					{
						"name":"106627903 focadhesin\tK27498 FOCAD; focadhesin"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"106621382 drosha; ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					},
					{
						"name":"106616146 probable oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"106616752 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"106625102 LOW QUALITY PROTEIN: enolase-like\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"106620541 PNPase; polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"106616195 ATP-dependent 6-phosphofructokinase isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"106623065 Pfk; ATP-dependent 6-phosphofructokinase isoform X3\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"106617854 Hsc70-5; heat shock 70 kDa protein cognate 5\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"106620015 heat shock protein 60A isoform X1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"106621233 Rrp4; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"106615801 Csl4; exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"106615937 Ski6; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"106619618 Rrp42; exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}
