{
	"name":"bpus01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"UP12_17155 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"UP12_17315 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"UP12_07385 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"UP12_13440 UDP-N-acetylmuramate--alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"UP12_07370 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"UP12_07360 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"UP12_02485 ddl; D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"UP12_02535 alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"UP12_06090 alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"UP12_12530 glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"UP12_06300 peptidase S66\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"UP12_07365 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"UP12_07380 UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"UP12_14695 UDP pyrophosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"UP12_08550 bacitracin ABC transporter permease\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"UP12_17030 UDP-diphosphatase\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase"
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"UP12_10010 peptidase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"UP12_05145 penicillin-binding protein\tK12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"UP12_14865 penicillin-binding protein\tK18770 pbpD; penicillin-binding protein 4 [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"UP12_17465 penicillin-binding protein\tK21464 pbpG; penicillin-binding protein 2D [EC:2.4.99.28 3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"UP12_07350 penicillin-binding protein\tK08724 pbpB; penicillin-binding protein 2B"
			},
			{
				"name":"UP12_07355 stage V sporulation protein D\tK08384 spoVD; stage V sporulation protein D (sporulation-specific penicillin-binding protein)"
			},
			{
				"name":"UP12_11315 penicillin-binding protein\tK21465 pbpA; penicillin-binding protein A"
			},
			{
				"name":"UP12_06745 penicillin-binding protein\tK21466 pbpH; penicillin-binding protein H"
			},
			{
				"name":"UP12_03745 penicillin-binding protein\tK21467 pbpC; penicillin-binding protein 3"
			},
			{
				"name":"UP12_11915 penicillin-binding protein\tK21468 pbpI; penicillin-binding protein 4B"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"UP12_00075 D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"UP12_10435 D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"UP12_10565 D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"UP12_09265 D-alanyl-D-alanine carboxypeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"UP12_01005 esterase\tK21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"UP12_07185 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"UP12_07375 stage V sporulation protein E\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"UP12_14080 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"UP12_14075 cell cycle protein\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"UP12_17790 rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase",
			"children":[
			{
				"name":"UP12_06800 L,D-transpeptidase\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"UP12_10840 L,D-transpeptidase\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"UP12_09630 peptidase M15\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
			}
			]
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"UP12_04860 peptidoglycan-binding protein\tK19224 lytE; peptidoglycan DL-endopeptidase LytE [EC:3.4.-.-]"
			},
			{
				"name":"UP12_16235 peptidase C40\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"UP12_09550 D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase\tK19220 cwlS; peptidoglycan DL-endopeptidase CwlS [EC:3.4.-.-]"
			},
			{
				"name":"UP12_15240 peptidase M23\tK21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Sortase",
			"children":[
			{
				"name":"UP12_02060 hypothetical protein\tK07284 srtA; sortase A [EC:3.4.22.70]"
			},
			{
				"name":"UP12_04155 peptidase C60\tK07284 srtA; sortase A [EC:3.4.22.70]"
			},
			{
				"name":"UP12_04740 hypothetical protein\tK07284 srtA; sortase A [EC:3.4.22.70]"
			},
			{
				"name":"UP12_18080 sortase\tK08600 srtB; sortase B [EC:3.4.22.71]"
			}
			]
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"UP12_11950 hypothetical protein\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			},
			{
				"name":"UP12_10310 spore cortex-lytic protein\tK27245 sleB; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"UP12_17150 stage II sporulation protein D\tK06381 spoIID; stage II sporulation protein D (peptidoglycan lytic transglycosylase) [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"UP12_00935 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"UP12_08475 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"UP12_12070 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"UP12_12560 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"UP12_16675 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein"
		}
		]
	}
	]
}