{ "name":"caci00001", "children":[ { "name":"09100 Metabolism", "children":[ { "name":"09101 Carbohydrate metabolism", "children":[ { "name":"00010 Glycolysis \/ Gluconeogenesis [PATH:caci00010]", "children":[ { "name":"CLOAM1376 putative Glucokinase (Glucose kinase) (glcK-like)\tK25026 glk; glucokinase [EC:2.7.1.2]" }, { "name":"CLOAM1751 pgi; Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"CLOAM0626 pfk; 6-phosphofructokinase (ATP-dependent phosphofructokinase) (ATP-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM1211 pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (6-phosphofructokinase, pyrophosphate dependent) (Pyrophosphate-dependent 6-phosphofructose-1-kinase) (PPi-dependent phosphofructokinase) (PPi-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM1837 fbaA; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"CLOAM1668 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"CLOAM1530 Glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM1840 gapA; Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM0802 pgk; 3-phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"CLOAM0341 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (Phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) (dPGM)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"CLOAM1651 eno; enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"CLOAM0519 ppdK; pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"CLOAM1531 putative Pyruvate phosphate dikinase,PEP\/pyruvate-binding:PEP-utilising enzyme, mobile region\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0324 putative pyruvate-ferredoxin oxidoreductase (por-like) or pyruvate-flavodoxin oxidoreductase (ydbK-like), 4Fe-4S domain\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"CLOAM0297 korA; 2-oxoglutarate ferredoxin oxidoreductase, alpha chain\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1002 vorA; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0296 korB; 2-oxoglutarate ferredoxin oxidoreductase, beta chain\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1003 vorB; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM1163 conserved hypothetical protein\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" } ] }, { "name":"00020 Citrate cycle (TCA cycle) [PATH:caci00020]", "children":[ { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0297 korA; 2-oxoglutarate ferredoxin oxidoreductase, alpha chain\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1002 vorA; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0296 korB; 2-oxoglutarate ferredoxin oxidoreductase, beta chain\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1003 vorB; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0295 korC; 2-oxoglutarate ferredoxin oxidoreductase, gamma chain\tK00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]" }, { "name":"CLOAM1004 vorC; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit\tK00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]" }, { "name":"CLOAM0298 putative 2-oxoglutarate ferredoxin oxidoreductase, 4Fe-4S ferredoxin subunit, delta chain (korD) (fdx module)\tK00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]" }, { "name":"CLOAM1001 vorD; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit (ferredoxin)\tK00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]" }, { "name":"CLOAM0022 Tartrate dehydratase alpha subunit (ttdA)\/Fumarate hydratase class I,alpha chain (N-terminal)\tK01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]" }, { "name":"CLOAM0023 tartrate dehydratase beta subunit (ttdB)\/fumarate hydratase class I, beta chain (C-terminal)\tK01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]" }, { "name":"CLOAM1717 putative S-methylmalonyl-CoA carboxyltransferase (Transcarboxylase) 5S and 1.3S subunits\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]" }, { "name":"CLOAM1163 conserved hypothetical protein\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" }, { "name":"CLOAM0324 putative pyruvate-ferredoxin oxidoreductase (por-like) or pyruvate-flavodoxin oxidoreductase (ydbK-like), 4Fe-4S domain\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" } ] }, { "name":"00030 Pentose phosphate pathway [PATH:caci00030]", "children":[ { "name":"CLOAM1751 pgi; Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"CLOAM1603 rpe; D-ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" }, { "name":"CLOAM1259 putative Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" }, { "name":"CLOAM0751 rpiB; ribose 5-phosphate isomerase B, also acts as allose 6-phosphate isomerase\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]" }, { "name":"CLOAM1243 deoC; Deoxyribose-phosphate aldolase\tK01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]" }, { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM1613 prsA; ribose-phosphate pyrophosphokinase (RPPK) (phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase)\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"CLOAM0709 aorA; Tungsten-containing aldehyde ferredoxin oxidoreductase, alpha chain\tK03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]" }, { "name":"CLOAM0705 putative hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"CLOAM1837 fbaA; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"CLOAM0626 pfk; 6-phosphofructokinase (ATP-dependent phosphofructokinase) (ATP-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM1211 pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (6-phosphofructokinase, pyrophosphate dependent) (Pyrophosphate-dependent 6-phosphofructose-1-kinase) (PPi-dependent phosphofructokinase) (PPi-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" } ] }, { "name":"00040 Pentose and glucuronate interconversions [PATH:caci00040]", "children":[ { "name":"CLOAM1468 ugd; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"CLOAM1098 putative glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"CLOAM1603 rpe; D-ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" }, { "name":"CLOAM1199 putative Sugar-phosphate aldolase\tK01629 rhaD; rhamnulose-1-phosphate aldolase [EC:4.1.2.19]" } ] }, { "name":"00051 Fructose and mannose metabolism [PATH:caci00051]", "children":[ { "name":"CLOAM1580 putative mannose-6-phosphate isomerase\tK01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]" }, { "name":"CLOAM1012 Phosphoglucomutase\/phosphomannomutase family protein\tK01840 manB; phosphomannomutase [EC:5.4.2.8]" }, { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM0349 mannose-1-phosphate guanylyltransferase\/mannose-6-phosphate isomerase,truncation\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]" }, { "name":"CLOAM1199 putative Sugar-phosphate aldolase\tK01629 rhaD; rhamnulose-1-phosphate aldolase [EC:4.1.2.19]" }, { "name":"CLOAM0626 pfk; 6-phosphofructokinase (ATP-dependent phosphofructokinase) (ATP-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM1211 pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (6-phosphofructokinase, pyrophosphate dependent) (Pyrophosphate-dependent 6-phosphofructose-1-kinase) (PPi-dependent phosphofructokinase) (PPi-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM0663 GDP-mannose 6-dehydrogenase (GMD)\tK00066 algD; GDP-mannose 6-dehydrogenase [EC:1.1.1.132]" }, { "name":"CLOAM1837 fbaA; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"CLOAM1668 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"CLOAM0751 rpiB; ribose 5-phosphate isomerase B, also acts as allose 6-phosphate isomerase\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]" } ] }, { "name":"00052 Galactose metabolism [PATH:caci00052]", "children":[ { "name":"CLOAM1469 galE; UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase)\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"CLOAM1098 putative glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM1376 putative Glucokinase (Glucose kinase) (glcK-like)\tK25026 glk; glucokinase [EC:2.7.1.2]" }, { "name":"CLOAM0626 pfk; 6-phosphofructokinase (ATP-dependent phosphofructokinase) (ATP-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM1211 pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (6-phosphofructokinase, pyrophosphate dependent) (Pyrophosphate-dependent 6-phosphofructose-1-kinase) (PPi-dependent phosphofructokinase) (PPi-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" } ] }, { "name":"00053 Ascorbate and aldarate metabolism", "children":[ { "name":"CLOAM1468 ugd; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" } ] }, { "name":"00500 Starch and sucrose metabolism [PATH:caci00500]", "children":[ { "name":"CLOAM1098 putative glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"CLOAM0642 Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase)\tK00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]" }, { "name":"CLOAM0378 glgP; glycogen phosphorylase\tK00688 PYG; glycogen phosphorylase [EC:2.4.1.1]" }, { "name":"CLOAM1831 glgP; glycogen phosphorylase\tK00688 PYG; glycogen phosphorylase [EC:2.4.1.1]" }, { "name":"CLOAM0877 putative alpha-amylase\tK07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1]" }, { "name":"CLOAM0972 putative Cyclomaltodextrinase\tK01208 cd; cyclomaltodextrinase \/ maltogenic alpha-amylase \/ neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135]" }, { "name":"CLOAM1039 putative 4-alpha-glucanotransferase\tK00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]" }, { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM1376 putative Glucokinase (Glucose kinase) (glcK-like)\tK25026 glk; glucokinase [EC:2.7.1.2]" }, { "name":"CLOAM1751 pgi; Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" } ] }, { "name":"00620 Pyruvate metabolism [PATH:caci00620]", "children":[ { "name":"CLOAM0324 putative pyruvate-ferredoxin oxidoreductase (por-like) or pyruvate-flavodoxin oxidoreductase (ydbK-like), 4Fe-4S domain\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"CLOAM0297 korA; 2-oxoglutarate ferredoxin oxidoreductase, alpha chain\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1002 vorA; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0296 korB; 2-oxoglutarate ferredoxin oxidoreductase, beta chain\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1003 vorB; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0181 ackA; acetate kinase A (propionate kinase 2)\tK00925 ackA; acetate kinase [EC:2.7.2.1]" }, { "name":"CLOAM0615 pta; phosphate acetyltransferase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]" }, { "name":"CLOAM0741 putative acylphosphatase (Acylphosphate phosphohydrolase)\tK01512 acyP; acylphosphatase [EC:3.6.1.7]" }, { "name":"CLOAM0897 metallo-beta-lactamase family protein\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]" }, { "name":"CLOAM1714 mae; NAD-dependent malic enzyme (NAD-ME)\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]" }, { "name":"CLOAM1513 putative Na+-transporting methylmalonyl-CoA\/oxaloacetate decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM1771 putative S-Methylmalonyl-CoA decarboxylase,sodium-translocating subunit, beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM1717 putative S-methylmalonyl-CoA carboxyltransferase (Transcarboxylase) 5S and 1.3S subunits\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]" }, { "name":"CLOAM0022 Tartrate dehydratase alpha subunit (ttdA)\/Fumarate hydratase class I,alpha chain (N-terminal)\tK01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]" }, { "name":"CLOAM0023 tartrate dehydratase beta subunit (ttdB)\/fumarate hydratase class I, beta chain (C-terminal)\tK01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]" }, { "name":"CLOAM1163 conserved hypothetical protein\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" }, { "name":"CLOAM0519 ppdK; pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"CLOAM1531 putative Pyruvate phosphate dikinase,PEP\/pyruvate-binding:PEP-utilising enzyme, mobile region\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00630 Glyoxylate and dicarboxylate metabolism [PATH:caci00630]", "children":[ { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"CLOAM0294 mce; methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"CLOAM0803 mutA; Methylmalonyl-CoA mutase small subunit (MCM-beta)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM0804 mutB; Methylmalonyl-CoA mutase large subunit (MCM-alpha)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM1413 gyaR; glyoxylate reductase (glycolate:NAD+ oxidoreductase)\tK00015 gyaR; glyoxylate reductase [EC:1.1.1.26]" }, { "name":"CLOAM0962 putative Phosphoglycolate phosphatase (PGPase) (PGP)\tK01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]" }, { "name":"CLOAM1216 putative Phosphoglycolate phosphatase (PGPase) (PGP)\tK01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]" }, { "name":"CLOAM0299 putative alanine--glyoxylate aminotransferase (alanine--glyoxylate transaminase) (Agt)\tK05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]" }, { "name":"CLOAM0729 putative kynurenine\/alpha-aminoadipate aminotransferase precursor (KAT\/AadAT) (kynurenine--oxoglutarate transaminase II) (kynurenine aminotransferase II) (kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (2-aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AadAT)\tK05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]" }, { "name":"CLOAM0630 glnA; glutamine synthetase (glutamate--ammonia ligase)\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"CLOAM0752 glyA; serine hydroxymethyltransferase (serine methylase) (SHMT)\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"CLOAM1385 gcvPA; glycine dehydrogenase [decarboxylating] subunit 1 (Glycine decarboxylase subunit 1) (Glycine cleavage system P-protein subunit 1)\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]" }, { "name":"CLOAM1384 gcvPB; glycine dehydrogenase [decarboxylating] subunit 2 (Glycine decarboxylase subunit 2) (Glycine cleavage system P-protein subunit 2)\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]" }, { "name":"CLOAM1023 gcvT; aminomethyltransferase (Glycine cleavage system T protein)\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0290 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" }, { "name":"CLOAM0705 putative hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"CLOAM1684 putative bifunctional glutamate synthase [NADPH] small chain \/ formate dehydrogenase large chain (Glutamate synthase beta subunit \/ formate dehydrogenase alpha subunit)\tK00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]" } ] }, { "name":"00640 Propanoate metabolism [PATH:caci00640]", "children":[ { "name":"CLOAM0181 ackA; acetate kinase A (propionate kinase 2)\tK00925 ackA; acetate kinase [EC:2.7.2.1]" }, { "name":"CLOAM0615 pta; phosphate acetyltransferase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0294 mce; methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"CLOAM0803 mutA; Methylmalonyl-CoA mutase small subunit (MCM-beta)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM0804 mutB; Methylmalonyl-CoA mutase large subunit (MCM-alpha)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" } ] }, { "name":"00650 Butanoate metabolism [PATH:caci00650]", "children":[ { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"CLOAM0042 atoD; Acetoacetate:butyrate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]" }, { "name":"CLOAM0043 atoA; Acetoacetate:butyrate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]" }, { "name":"CLOAM0397 butyrate kinase\tK00929 buk; butyrate kinase [EC:2.7.2.7]" }, { "name":"CLOAM0749 pta; Phosphotransacetylase\tK00634 ptb; phosphate butyryltransferase [EC:2.3.1.19]" }, { "name":"CLOAM1513 putative Na+-transporting methylmalonyl-CoA\/oxaloacetate decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM1771 putative S-Methylmalonyl-CoA decarboxylase,sodium-translocating subunit, beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM0324 putative pyruvate-ferredoxin oxidoreductase (por-like) or pyruvate-flavodoxin oxidoreductase (ydbK-like), 4Fe-4S domain\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"CLOAM0297 korA; 2-oxoglutarate ferredoxin oxidoreductase, alpha chain\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1002 vorA; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0296 korB; 2-oxoglutarate ferredoxin oxidoreductase, beta chain\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1003 vorB; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" } ] }, { "name":"00660 C5-Branched dibasic acid metabolism" }, { "name":"00562 Inositol phosphate metabolism [PATH:caci00562]", "children":[ { "name":"CLOAM0423 ino1; Inositol-3-phosphate synthase (Myo-inositol-1-phosphate synthase) (MI-1-P synthase) (IPS)\tK01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]" }, { "name":"CLOAM0421 conserved hypothetical protein\tK07281 ipct; 1L-myo-inositol 1-phosphate cytidylyltransferase [EC:2.7.7.74]" }, { "name":"CLOAM1668 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" } ] }, { "name":"00566 Sulfoquinovose metabolism" } ] }, { "name":"09102 Energy metabolism", "children":[ { "name":"00190 Oxidative phosphorylation [PATH:caci00190]", "children":[ { "name":"CLOAM1182 putative [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit gamma (hymA-like)\tK00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]" }, { "name":"CLOAM1686 [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit gamma (hymA-like)\tK00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]" }, { "name":"CLOAM1685 [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase); putative signal peptide\tK00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]" }, { "name":"CLOAM1180 hymC; [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit alpha\tK00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]" }, { "name":"CLOAM1052 V-type ATP synthase alpha chain 1 (V-type ATPase subunit A 1)\tK02117 ATPVA; V\/A-type H+\/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]" }, { "name":"CLOAM1053 V-type ATP synthase beta chain 1 (V-type ATPase subunit B 1)\tK02118 ATPVB; V\/A-type H+\/Na+-transporting ATPase subunit B" }, { "name":"CLOAM1054 V-type ATP synthase subunit D\tK02120 ATPVD; V\/A-type H+\/Na+-transporting ATPase subunit D" }, { "name":"CLOAM1050 putative V-type ATPase, subunit E\tK02121 ATPVE; V\/A-type H+\/Na+-transporting ATPase subunit E" }, { "name":"CLOAM1055 putative V(Vacuolar)-type Na+ ATP synthase subunit I\tK02123 ATPVI; V\/A-type H+\/Na+-transporting ATPase subunit I" }, { "name":"CLOAM1056 putative V(Vacuolar)-type Na+-ATP synthase subunit K\tK02124 ATPVK; V\/A-type H+\/Na+-transporting ATPase subunit K" } ] }, { "name":"00195 Photosynthesis" }, { "name":"00196 Photosynthesis - antenna proteins" }, { "name":"00710 Carbon fixation by Calvin cycle [PATH:caci00710]", "children":[ { "name":"CLOAM0802 pgk; 3-phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"CLOAM1530 Glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM1840 gapA; Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM1837 fbaA; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"CLOAM1259 putative Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" }, { "name":"CLOAM0751 rpiB; ribose 5-phosphate isomerase B, also acts as allose 6-phosphate isomerase\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]" }, { "name":"CLOAM1668 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"CLOAM1603 rpe; D-ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" }, { "name":"CLOAM1163 conserved hypothetical protein\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" }, { "name":"CLOAM0519 ppdK; pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"CLOAM1531 putative Pyruvate phosphate dikinase,PEP\/pyruvate-binding:PEP-utilising enzyme, mobile region\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" } ] }, { "name":"00720 Other carbon fixation pathways [PATH:caci00720]", "children":[ { "name":"CLOAM0324 putative pyruvate-ferredoxin oxidoreductase (por-like) or pyruvate-flavodoxin oxidoreductase (ydbK-like), 4Fe-4S domain\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"CLOAM0519 ppdK; pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"CLOAM1531 putative Pyruvate phosphate dikinase,PEP\/pyruvate-binding:PEP-utilising enzyme, mobile region\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"CLOAM1717 putative S-methylmalonyl-CoA carboxyltransferase (Transcarboxylase) 5S and 1.3S subunits\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]" }, { "name":"CLOAM0022 Tartrate dehydratase alpha subunit (ttdA)\/Fumarate hydratase class I,alpha chain (N-terminal)\tK01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]" }, { "name":"CLOAM0023 tartrate dehydratase beta subunit (ttdB)\/fumarate hydratase class I, beta chain (C-terminal)\tK01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"CLOAM0297 korA; 2-oxoglutarate ferredoxin oxidoreductase, alpha chain\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1002 vorA; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0296 korB; 2-oxoglutarate ferredoxin oxidoreductase, beta chain\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM1003 vorB; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"CLOAM0295 korC; 2-oxoglutarate ferredoxin oxidoreductase, gamma chain\tK00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]" }, { "name":"CLOAM1004 vorC; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit\tK00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]" }, { "name":"CLOAM0298 putative 2-oxoglutarate ferredoxin oxidoreductase, 4Fe-4S ferredoxin subunit, delta chain (korD) (fdx module)\tK00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]" }, { "name":"CLOAM1001 vorD; pyruvate:ferredoxin and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit (ferredoxin)\tK00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]" }, { "name":"CLOAM0294 mce; methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"CLOAM0803 mutA; Methylmalonyl-CoA mutase small subunit (MCM-beta)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM0804 mutB; Methylmalonyl-CoA mutase large subunit (MCM-alpha)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM0539 folD; FolD bifunctional protein [Includes: Methylenetetrahydrofolate dehydrogenase; Methenyltetrahydrofolate cyclohydrolase]\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]" }, { "name":"CLOAM0615 pta; phosphate acetyltransferase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]" }, { "name":"CLOAM0181 ackA; acetate kinase A (propionate kinase 2)\tK00925 ackA; acetate kinase [EC:2.7.2.1]" } ] }, { "name":"00680 Methane metabolism [PATH:caci00680]", "children":[ { "name":"CLOAM1684 putative bifunctional glutamate synthase [NADPH] small chain \/ formate dehydrogenase large chain (Glutamate synthase beta subunit \/ formate dehydrogenase alpha subunit)\tK00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]" }, { "name":"CLOAM0752 glyA; serine hydroxymethyltransferase (serine methylase) (SHMT)\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"CLOAM0705 putative hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"CLOAM1651 eno; enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"CLOAM1837 fbaA; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"CLOAM0626 pfk; 6-phosphofructokinase (ATP-dependent phosphofructokinase) (ATP-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM1211 pfp; Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (6-phosphofructokinase, pyrophosphate dependent) (Pyrophosphate-dependent 6-phosphofructose-1-kinase) (PPi-dependent phosphofructokinase) (PPi-PFK)\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"CLOAM0181 ackA; acetate kinase A (propionate kinase 2)\tK00925 ackA; acetate kinase [EC:2.7.2.1]" }, { "name":"CLOAM0615 pta; phosphate acetyltransferase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]" }, { "name":"CLOAM0341 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (Phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) (dPGM)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"CLOAM1772 serA; D-3-phosphoglycerate dehydrogenase (PGDH)\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"CLOAM0992 serC; phosphoserine aminotransferase (PSAT) (phosphoserine transaminase)\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" }, { "name":"CLOAM1159 mdh; Malate dehydrogenase\tK05884 comC; L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337]" } ] }, { "name":"00910 Nitrogen metabolism [PATH:caci00910]", "children":[ { "name":"CLOAM0445 hcp; Hydroxylamine reductase (Hybrid-cluster protein) (HCP)\tK05601 hcp; hydroxylamine reductase [EC:1.7.99.1]" }, { "name":"CLOAM1212 gdhB; NAD-specific glutamate dehydrogenase (NAD-GDH) (NADH-dependent glutamate dehydrogenase)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]" }, { "name":"CLOAM0630 glnA; glutamine synthetase (glutamate--ammonia ligase)\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"CLOAM0886 cpkA; carbamate kinase (carbamate kinase-like) (carbamate kinase-like carbamoylphosphate synthetase)\tK00926 arcC; carbamate kinase [EC:2.7.2.2]" } ] }, { "name":"00920 Sulfur metabolism [PATH:caci00920]", "children":[ { "name":"CLOAM0268 hypothetical protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]" }, { "name":"CLOAM0983 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit\tK01738 cysK; cysteine synthase [EC:2.5.1.47]" } ] } ] }, { "name":"09103 Lipid metabolism", "children":[ { "name":"00061 Fatty acid biosynthesis [PATH:caci00061]", "children":[ { "name":"CLOAM0252 acpP; Acyl carrier protein (ACP)\tK02078 acpP; acyl carrier protein" }, { "name":"CLOAM0680 putative acyl carrier protein (acpP-like)\tK02078 acpP; acyl carrier protein" }, { "name":"CLOAM0254 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"CLOAM0255 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"CLOAM0689 beta-ketoacyl-acyl carrier protein synthase (fabH-like)\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"CLOAM0251 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"CLOAM0253 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0682 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0690 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM1381 lpxC_fabZ; LpxC\/fabZ bifunctional enzyme [Includes: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase)]\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]" } ] }, { "name":"00062 Fatty acid elongation" }, { "name":"00071 Fatty acid degradation [PATH:caci00071]", "children":[ { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00073 Cutin, suberine and wax biosynthesis" }, { "name":"00074 Mycolic acid biosynthesis [PATH:caci00074]", "children":[ { "name":"CLOAM1460 acpS; Holo-[acyl-carrier-protein] synthase (Holo-ACP synthase) (4'-phosphopantetheinyl transferase acpS)\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]" }, { "name":"CLOAM0252 acpP; Acyl carrier protein (ACP)\tK02078 acpP; acyl carrier protein" }, { "name":"CLOAM0680 putative acyl carrier protein (acpP-like)\tK02078 acpP; acyl carrier protein" }, { "name":"CLOAM0254 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"CLOAM1438 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK11610 mabA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-]" } ] }, { "name":"00100 Steroid biosynthesis" }, { "name":"00120 Primary bile acid biosynthesis" }, { "name":"00121 Secondary bile acid biosynthesis" }, { "name":"00140 Steroid hormone biosynthesis" }, { "name":"00561 Glycerolipid metabolism [PATH:caci00561]", "children":[ { "name":"CLOAM0705 putative hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"CLOAM0256 plsX; fatty acid\/phospholipid synthesis protein,methyltransferase domain\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]" }, { "name":"CLOAM0162 hypothetical protein; putative membrane protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"CLOAM0370 conserved hypothetical protein; putative membrane protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"CLOAM1445 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) (plsC)\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" } ] }, { "name":"00564 Glycerophospholipid metabolism [PATH:caci00564]", "children":[ { "name":"CLOAM0870 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase)\tK00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]" }, { "name":"CLOAM0162 hypothetical protein; putative membrane protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"CLOAM0370 conserved hypothetical protein; putative membrane protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"CLOAM1445 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) (plsC)\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"CLOAM1573 cdsA; Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) (CDP-diglyceride pyrophosphorylase) (CDP-diacylglycerol synthase) (CDS) (CTP:phosphatidate cytidylyltransferase) (CDP-DAG synthase) (CDP-DG synthetase)\tK00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]" }, { "name":"CLOAM0330 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Phosphatidylglycerophosphate synthase) (PGP synthase)\tK00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]" }, { "name":"CLOAM0005 pgpA; phosphatidylglycerophosphatase A\tK01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]" }, { "name":"CLOAM0597 cls; cardiolipin synthetase 2 (Cardiolipin synthase 2) (CL synthase 2)\tK06131 clsA_B; cardiolipin synthase A\/B [EC:2.7.8.-]" } ] }, { "name":"00565 Ether lipid metabolism" }, { "name":"00600 Sphingolipid metabolism [PATH:caci00600]", "children":[ { "name":"CLOAM1164 8-amino-7-oxononanoate synthase (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase)\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]" }, { "name":"CLOAM0161 conserved hypothetical protein\tK28560 bcerS; bacterial ceramide synthase [EC:2.3.1.-]" }, { "name":"CLOAM1261 putative UDP-glucose 4-epimerase\tK28561 cerR; ceramide reductase [EC:1.-.-.-]" } ] }, { "name":"00590 Arachidonic acid metabolism" }, { "name":"00591 Linoleic acid metabolism" }, { "name":"00592 alpha-Linolenic acid metabolism" }, { "name":"01040 Biosynthesis of unsaturated fatty acids" } ] }, { "name":"09104 Nucleotide metabolism", "children":[ { "name":"00230 Purine metabolism [PATH:caci00230]", "children":[ { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM1613 prsA; ribose-phosphate pyrophosphokinase (RPPK) (phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase)\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"CLOAM0369 purF; amidophosphoribosyltransferase precursor (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPATase)\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" }, { "name":"CLOAM0428 purD; phosphoribosylamine--glycine ligase (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase)\tK01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]" }, { "name":"CLOAM1541 purN; phosphoribosylglycinamide formyltransferase (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]" }, { "name":"CLOAM1016 purL; phosphoribosylformylglycinamidine synthase II (FGAM synthase II) (formylglycinamide ribonucleotide amidotransferase) (small PurL), ATP and FGAR binding domain\tK23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]" }, { "name":"CLOAM0594 purS; phosphoribosylformylglycinamidine synthase III (FGAM synthase III) (formylglycinamide ribonucleotide amidotransferase), PurS component\tK23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]" }, { "name":"CLOAM0593 purQ; phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (formylglycinamide ribonucleotide amidotransferase), glutaminase domain\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"CLOAM0611 purM; phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase)\tK01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]" }, { "name":"CLOAM0342 purE; phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC)\tK01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]" }, { "name":"CLOAM0764 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase)\tK01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]" }, { "name":"CLOAM0107 purB; adenylosuccinate lyase (adenylosuccinase) (ASL) (glutamyl-tRNA synthetase regulatory factor)\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]" }, { "name":"CLOAM1899 purH; Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"CLOAM0524 putative 5'-nucleotidase\tK11751 ushA; 5'-nucleotidase \/ UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]" }, { "name":"CLOAM1168 surE; broad specificity 5'(3')-nucleotidase and polyphosphatase\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]" }, { "name":"CLOAM0405 Purine nucleoside phosphorylase 1 (Purine nucleoside phosphorylase I) (PNP I) (PU-NPase I) (Inosine phosphorylase)\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]" }, { "name":"CLOAM1647 yaiE; conserved hypothetical protein\tK09913 ppnP; purine\/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2]" }, { "name":"CLOAM0827 conserved hypothetical protein\tK05810 LACC1; purine-nucleoside\/S-methyl-5'-thioadenosine phosphorylase \/ adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]" }, { "name":"CLOAM0832 hpt; Hypoxanthine-guanine phosphoribosyltransferase\tK00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]" }, { "name":"CLOAM1588 guaB; Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) (Superoxide-inducible protein 12) (SOI12)\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]" }, { "name":"CLOAM0822 ndk; nucleoside diphosphate kinase (NDK) (NDP kinase) (nucleoside-2-P kinase)\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"CLOAM0517 Xanthosine triphosphate pyrophosphatase\tK01519 rdgB; XTP\/dITP diphosphohydrolase [EC:3.6.1.66]" }, { "name":"CLOAM1779 xdhA; xanthine dehydrogenase, FAD binding and 2Fe-2S ferredoxin-like subunits, medium and small chains\tK13481 xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4]" }, { "name":"CLOAM1780 xdhB; xanthine dehydrogenase, molybdenum binding subunit, large chain\tK13482 xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4]" }, { "name":"CLOAM0898 guaA; GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]" }, { "name":"CLOAM0436 putative guanine deaminase\tK01487 guaD; guanine deaminase [EC:3.5.4.3]" }, { "name":"CLOAM0289 gmk; Guanylate kinase (GMP kinase)\tK00942 gmk; guanylate kinase [EC:2.7.4.8]" }, { "name":"CLOAM0913 putative B12-dependent ribonucleoside-diphosphate\/-triphosphate reductase (nrdJ-like)\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"CLOAM1253 nrdD; Anaerobic ribonucleoside-triphosphate reductase (Oxygen-sensitive ribonucleoside-triphosphate reductase)\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]" }, { "name":"CLOAM1621 DGTP triphosphohydrolase\tK01129 dgt; dGTPase [EC:3.1.5.1]" }, { "name":"CLOAM0753 putative Exopolyphosphatase\tK01524 ppx-gppA; exopolyphosphatase \/ guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]" }, { "name":"CLOAM1151 putative Adenylate cyclase\tK01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]" }, { "name":"CLOAM1343 putative Adenylate cyclase\tK01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]" }, { "name":"CLOAM1850 purA; Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase)\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]" }, { "name":"CLOAM0847 putative Adenosine deaminase\tK01488 add; adenosine deaminase [EC:3.5.4.4]" }, { "name":"CLOAM1703 putative adenosine deaminase 2 (Adenosine aminohydrolase 2)\tK01488 add; adenosine deaminase [EC:3.5.4.4]" }, { "name":"CLOAM0538 Ser\/Thr protein phosphatase family protein\tK09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]" }, { "name":"CLOAM1458 adk; Adenylate kinase (ATP-AMP transphosphorylase)\tK00939 adk; adenylate kinase [EC:2.7.4.3]" }, { "name":"CLOAM0362 HIT family protein\tK19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]" }, { "name":"CLOAM0886 cpkA; carbamate kinase (carbamate kinase-like) (carbamate kinase-like carbamoylphosphate synthetase)\tK00926 arcC; carbamate kinase [EC:2.7.2.2]" } ] }, { "name":"00240 Pyrimidine metabolism [PATH:caci00240]", "children":[ { "name":"CLOAM1784 Similar to Biotin carboxylase\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"CLOAM1311 pyrB; aspartate carbamoyltransferase (aspartate transcarbamylase) (ATCase)\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]" }, { "name":"CLOAM1310 pyrC; dihydroorotase (DHOase)\tK01465 URA4; dihydroorotase [EC:3.5.2.3]" }, { "name":"CLOAM1308 pyrD; dihydroorotate dehydrogenase, catalytic subunit (Dihydroorotate oxidase) (DHOdehase) (DHODase) (DHOD)\tK17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]" }, { "name":"CLOAM1309 pyrK; dihydroorotate dehydrogenase electron transfer subunit\tK02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit" }, { "name":"CLOAM1005 fused protein: Orotate phosphoribosyltransferase (pyrE-like) (C_terminal); unknown domain (N-terminal)\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]" }, { "name":"CLOAM1720 pyrF; orotidine 5'-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase)\tK01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]" }, { "name":"CLOAM1888 pyrH; uridylate kinase (UK) (uridine monophosphate kinase) (UMP kinase)\tK09903 pyrH; uridylate kinase [EC:2.7.4.22]" }, { "name":"CLOAM0822 ndk; nucleoside diphosphate kinase (NDK) (NDP kinase) (nucleoside-2-P kinase)\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"CLOAM0993 maf; maf protein\tK06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]" }, { "name":"CLOAM0808 pyrG; CTP synthase (UTP--ammonia ligase) (CTP synthetase)\tK01937 pyrG; CTP synthase [EC:6.3.4.2]" }, { "name":"CLOAM0819 Uridine kinase (Uridine monophosphokinase) (Cytidine monophosphokinase)\tK00876 udk; uridine kinase [EC:2.7.1.48]" }, { "name":"CLOAM1303 udk; Uridine kinase\tK00876 udk; uridine kinase [EC:2.7.1.48]" }, { "name":"CLOAM0524 putative 5'-nucleotidase\tK11751 ushA; 5'-nucleotidase \/ UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]" }, { "name":"CLOAM1168 surE; broad specificity 5'(3')-nucleotidase and polyphosphatase\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]" }, { "name":"CLOAM1647 yaiE; conserved hypothetical protein\tK09913 ppnP; purine\/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2]" }, { "name":"CLOAM1719 pyrR; Bifunctional protein : Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase (UPRTase)\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]" }, { "name":"CLOAM0538 Ser\/Thr protein phosphatase family protein\tK09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]" }, { "name":"CLOAM0999 indA; uncharacterized enzyme involved in pigment biosynthesis\tK16329 psuG; pseudouridylate synthase [EC:4.2.1.70]" }, { "name":"CLOAM1645 deoA; Thymidine phosphorylase\tK00756 pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]" }, { "name":"CLOAM1514 cdd; Cytidine deaminase\tK01489 cdd; cytidine deaminase [EC:3.5.4.5]" }, { "name":"CLOAM1253 nrdD; Anaerobic ribonucleoside-triphosphate reductase (Oxygen-sensitive ribonucleoside-triphosphate reductase)\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]" }, { "name":"CLOAM0913 putative B12-dependent ribonucleoside-diphosphate\/-triphosphate reductase (nrdJ-like)\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"CLOAM1358 cytidine\/deoxycytidylate deaminase family protein\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]" }, { "name":"CLOAM0356 tmk; thymidylate kinase\tK00943 tmk; dTMP kinase [EC:2.7.4.9]" }, { "name":"CLOAM0327 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"CLOAM0402 tdk; thymidine kinase\tK00857 tdk; thymidine kinase [EC:2.7.1.21]" }, { "name":"CLOAM1631 putative dihydropyrimidine dehydrogenase [NADP+] (DPD) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase) (pydA)\tK00207 DPYD; dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]" } ] } ] }, { "name":"09105 Amino acid metabolism", "children":[ { "name":"00250 Alanine, aspartate and glutamate metabolism [PATH:caci00250]", "children":[ { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM0357 putative NADH-dependent fumarate reductase (frd)\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]" }, { "name":"CLOAM0923 ansB; L-asparaginase (L-asparagine amidohydrolase) (L-ASNase)\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]" }, { "name":"CLOAM0669 putative Asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"CLOAM1585 asnB; asparagine synthetase (Glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"CLOAM1850 purA; Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase)\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]" }, { "name":"CLOAM0107 purB; adenylosuccinate lyase (adenylosuccinase) (ASL) (glutamyl-tRNA synthetase regulatory factor)\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]" }, { "name":"CLOAM1311 pyrB; aspartate carbamoyltransferase (aspartate transcarbamylase) (ATCase)\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]" }, { "name":"CLOAM1212 gdhB; NAD-specific glutamate dehydrogenase (NAD-GDH) (NADH-dependent glutamate dehydrogenase)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]" }, { "name":"CLOAM1154 rocA; Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)\tK00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]" }, { "name":"CLOAM0630 glnA; glutamine synthetase (glutamate--ammonia ligase)\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"CLOAM1784 Similar to Biotin carboxylase\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"CLOAM0593 purQ; phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (formylglycinamide ribonucleotide amidotransferase), glutaminase domain\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"CLOAM0957 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (Hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"CLOAM1490 putative glutamine-fructose-6-phosphate transaminase [isomerizing] (glucosamine--fructose-6-phosphate aminotransferase)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"CLOAM0369 purF; amidophosphoribosyltransferase precursor (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPATase)\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" } ] }, { "name":"00260 Glycine, serine and threonine metabolism [PATH:caci00260]", "children":[ { "name":"CLOAM0441 lysC; Aspartokinase 2 (Aspartokinase II) (Aspartate kinase 2) [Contains: Aspartokinase II alpha subunit; Aspartokinase II beta subunit]\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"CLOAM0633 asd; Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH)\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"CLOAM0719 putative threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" }, { "name":"CLOAM1665 Low-specificity L-threonine aldolase\tK01620 ltaE; threonine aldolase [EC:4.1.2.48]" }, { "name":"CLOAM0752 glyA; serine hydroxymethyltransferase (serine methylase) (SHMT)\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"CLOAM0705 putative hydroxypyruvate reductase\tK11529 gck; glycerate 2-kinase [EC:2.7.1.165]" }, { "name":"CLOAM0341 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (Phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) (dPGM)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"CLOAM1772 serA; D-3-phosphoglycerate dehydrogenase (PGDH)\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"CLOAM0992 serC; phosphoserine aminotransferase (PSAT) (phosphoserine transaminase)\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" }, { "name":"CLOAM0960 kbl; glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]" }, { "name":"CLOAM1385 gcvPA; glycine dehydrogenase [decarboxylating] subunit 1 (Glycine decarboxylase subunit 1) (Glycine cleavage system P-protein subunit 1)\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]" }, { "name":"CLOAM1384 gcvPB; glycine dehydrogenase [decarboxylating] subunit 2 (Glycine decarboxylase subunit 2) (Glycine cleavage system P-protein subunit 2)\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]" }, { "name":"CLOAM1023 gcvT; aminomethyltransferase (Glycine cleavage system T protein)\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0290 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" } ] }, { "name":"00270 Cysteine and methionine metabolism [PATH:caci00270]", "children":[ { "name":"CLOAM0983 Pyridoxal-5'-phosphate-dependent enzyme, beta subunit\tK01738 cysK; cysteine synthase [EC:2.5.1.47]" }, { "name":"CLOAM1025 class-II pyridoxal-phosphate-dependent aminotransferase (malY\/patB-like)\tK14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]" }, { "name":"CLOAM1766 metK; S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT)\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"CLOAM0827 conserved hypothetical protein\tK05810 LACC1; purine-nucleoside\/S-methyl-5'-thioadenosine phosphorylase \/ adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]" }, { "name":"CLOAM1777 ssnA; Cytosine deaminase and related metal-dependent hydrolase\tK12960 mtaD; 5-methylthioadenosine\/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]" }, { "name":"CLOAM1776 putative translation initiation factor, aIF-2BI family\tK08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]" }, { "name":"CLOAM1471 ahcY; S-adenosyl-L-homocysteine hydrolase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"CLOAM0441 lysC; Aspartokinase 2 (Aspartokinase II) (Aspartate kinase 2) [Contains: Aspartokinase II alpha subunit; Aspartokinase II beta subunit]\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"CLOAM0633 asd; Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH)\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1772 serA; D-3-phosphoglycerate dehydrogenase (PGDH)\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"CLOAM0992 serC; phosphoserine aminotransferase (PSAT) (phosphoserine transaminase)\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" } ] }, { "name":"00280 Valine, leucine and isoleucine degradation [PATH:caci00280]", "children":[ { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0294 mce; methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"CLOAM0803 mutA; Methylmalonyl-CoA mutase small subunit (MCM-beta)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM0804 mutB; Methylmalonyl-CoA mutase large subunit (MCM-alpha)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00290 Valine, leucine and isoleucine biosynthesis" }, { "name":"00300 Lysine biosynthesis [PATH:caci00300]", "children":[ { "name":"CLOAM0441 lysC; Aspartokinase 2 (Aspartokinase II) (Aspartate kinase 2) [Contains: Aspartokinase II alpha subunit; Aspartokinase II beta subunit]\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"CLOAM0633 asd; Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH)\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"CLOAM0032 dapA; dihydrodipicolinate synthase (DHDPS)\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]" }, { "name":"CLOAM0281 dapB; dihydrodipicolinate reductase (DHPR)\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]" }, { "name":"CLOAM1024 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (Tetrahydrodipicolinate N-succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)\tK00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]" }, { "name":"CLOAM0282 dapF; diaminopimelate epimerase (DAP epimerase)\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]" }, { "name":"CLOAM1785 lysA; diaminopimelate decarboxylase (DAP decarboxylase)\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" }, { "name":"CLOAM0632 putative Metal-dependent amidase\/aminoacylase\/carboxypeptidase\tK05823 dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]" }, { "name":"CLOAM0299 putative alanine--glyoxylate aminotransferase (alanine--glyoxylate transaminase) (Agt)\tK05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]" }, { "name":"CLOAM0729 putative kynurenine\/alpha-aminoadipate aminotransferase precursor (KAT\/AadAT) (kynurenine--oxoglutarate transaminase II) (kynurenine aminotransferase II) (kynurenine--oxoglutarate aminotransferase II) (2-aminoadipate transaminase) (2-aminoadipate aminotransferase) (Alpha-aminoadipate aminotransferase) (AadAT)\tK05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]" }, { "name":"CLOAM0786 putative bifunctional MurE\/MurF enzyme [Includes: UDP-N-acetylmuramoylalanyl-D-glutamate--2; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase)] (partial match,murE\/murF-like)\tK15792 murEF; MurE\/MurF fusion protein [EC:6.3.2.13 6.3.2.10]" } ] }, { "name":"00310 Lysine degradation [PATH:caci00310]", "children":[ { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"CLOAM1349 kamA; L-lysine 2,3-aminomutase (KAM) (LAM)\tK01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2]" }, { "name":"CLOAM1504 kamD; L-beta-lysine 5,6-aminomutase alpha subunit\tK01844 kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3]" }, { "name":"CLOAM1503 kamE; L-beta-lysine 5,6-aminomutase beta subunit\tK18011 kamE; beta-lysine 5,6-aminomutase beta subunit [EC:5.4.3.3]" }, { "name":"CLOAM1348 kdd; 3,5-diaminohexanoate dehydrogenase\tK18012 kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11]" }, { "name":"CLOAM0912 kce; 3-keto-5-aminohexanoate cleavage enzyme\tK18013 kce; 3-keto-5-aminohexanoate cleavage enzyme [EC:2.3.1.247]" }, { "name":"CLOAM0042 atoD; Acetoacetate:butyrate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]" }, { "name":"CLOAM0043 atoA; Acetoacetate:butyrate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]" } ] }, { "name":"00220 Arginine biosynthesis [PATH:caci00220]", "children":[ { "name":"CLOAM0089 argI; Ornithine carbamoyltransferase (OTCase)\tK00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]" }, { "name":"CLOAM0593 purQ; phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (formylglycinamide ribonucleotide amidotransferase), glutaminase domain\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"CLOAM0630 glnA; glutamine synthetase (glutamate--ammonia ligase)\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"CLOAM1784 Similar to Biotin carboxylase\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"CLOAM0886 cpkA; carbamate kinase (carbamate kinase-like) (carbamate kinase-like carbamoylphosphate synthetase)\tK00926 arcC; carbamate kinase [EC:2.7.2.2]" }, { "name":"CLOAM1212 gdhB; NAD-specific glutamate dehydrogenase (NAD-GDH) (NADH-dependent glutamate dehydrogenase)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]" }, { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" } ] }, { "name":"00330 Arginine and proline metabolism [PATH:caci00330]", "children":[ { "name":"CLOAM1160 Ornithine decarboxylase\tK01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]" }, { "name":"CLOAM0660 putative GCN5-related N-acetyltransferase\tK00657 speG; diamine N-acetyltransferase [EC:2.3.1.57]" }, { "name":"CLOAM1147 putative ornithine\/acetylornithine\/succinyldiaminopimelate aminotransferase (ornithine\/acetylornithine\/succinyldiaminopimelate transaminase) (dapC-like)\tK00819 rocD; ornithine--oxo-acid transaminase [EC:2.6.1.13]" }, { "name":"CLOAM1154 rocA; Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase)\tK00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]" }, { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" } ] }, { "name":"00340 Histidine metabolism [PATH:caci00340]", "children":[ { "name":"CLOAM0138 putative aromatic amino acid aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"CLOAM0919 putative Histidinol-phosphatase\tK04486 hisK; histidinol-phosphatase (PHP family) [EC:3.1.3.15]" }, { "name":"CLOAM0511 hutH; histidine ammonia-lyase (Histidase)\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]" }, { "name":"CLOAM1099 hutU; urocanate hydratase (Urocanase) (Imidazolonepropionate hydrolase)\tK01712 hutU; urocanate hydratase [EC:4.2.1.49]" }, { "name":"CLOAM0424 hutI; imidazolonepropionase (imidazolone-5-propionate hydrolase)\tK01468 hutI; imidazolonepropionase [EC:3.5.2.7]" }, { "name":"CLOAM0177 ftcd; Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (Formiminotetrahydrofolate cyclodeaminase)]\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" } ] }, { "name":"00350 Tyrosine metabolism [PATH:caci00350]", "children":[ { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM0138 putative aromatic amino acid aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" } ] }, { "name":"00360 Phenylalanine metabolism [PATH:caci00360]", "children":[ { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM0138 putative aromatic amino acid aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" } ] }, { "name":"00380 Tryptophan metabolism [PATH:caci00380]", "children":[ { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:caci00400]", "children":[ { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM0138 putative aromatic amino acid aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" } ] } ] }, { "name":"09106 Metabolism of other amino acids", "children":[ { "name":"00410 beta-Alanine metabolism [PATH:caci00410]", "children":[ { "name":"CLOAM1081 panD; Aspartate 1-decarboxylase precursor (Aspartate alpha-decarboxylase)\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]" }, { "name":"CLOAM1082 panC; Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate activating enzyme)\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]" }, { "name":"CLOAM1631 putative dihydropyrimidine dehydrogenase [NADP+] (DPD) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase) (pydA)\tK00207 DPYD; dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]" } ] }, { "name":"00430 Taurine and hypotaurine metabolism [PATH:caci00430]", "children":[ { "name":"CLOAM0615 pta; phosphate acetyltransferase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]" }, { "name":"CLOAM0181 ackA; acetate kinase A (propionate kinase 2)\tK00925 ackA; acetate kinase [EC:2.7.2.1]" } ] }, { "name":"00440 Phosphonate and phosphinate metabolism" }, { "name":"00450 Selenocompound metabolism [PATH:caci00450]", "children":[ { "name":"CLOAM1025 class-II pyridoxal-phosphate-dependent aminotransferase (malY\/patB-like)\tK14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]" }, { "name":"CLOAM1697 trxB; Thioredoxin reductase\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]" }, { "name":"CLOAM0440 Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS)\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" } ] }, { "name":"00460 Cyanoamino acid metabolism [PATH:caci00460]", "children":[ { "name":"CLOAM0923 ansB; L-asparaginase (L-asparagine amidohydrolase) (L-ASNase)\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]" }, { "name":"CLOAM0752 glyA; serine hydroxymethyltransferase (serine methylase) (SHMT)\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" } ] }, { "name":"00470 D-Amino acid metabolism [PATH:caci00470]", "children":[ { "name":"CLOAM1339 ddlB; D-alanine--D-alanine ligase (D-alanylalanine synthetase) (D-Ala-D-Ala ligase)\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"CLOAM0593 purQ; phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (formylglycinamide ribonucleotide amidotransferase), glutaminase domain\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]" }, { "name":"CLOAM0911 murI; Glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]" }, { "name":"CLOAM0784 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase) (D-glutamic acid adding enzyme)\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"CLOAM0282 dapF; diaminopimelate epimerase (DAP epimerase)\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]" }, { "name":"CLOAM1785 lysA; diaminopimelate decarboxylase (DAP decarboxylase)\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" }, { "name":"CLOAM1504 kamD; L-beta-lysine 5,6-aminomutase alpha subunit\tK01844 kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3]" }, { "name":"CLOAM1503 kamE; L-beta-lysine 5,6-aminomutase beta subunit\tK18011 kamE; beta-lysine 5,6-aminomutase beta subunit [EC:5.4.3.3]" } ] }, { "name":"00480 Glutathione metabolism [PATH:caci00480]", "children":[ { "name":"CLOAM0131 pepA; cytosol aminopeptidase (leucine aminopeptidase) (LAP) (leucyl aminopeptidase) (aminopeptidase A\/I)\tK01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]" }, { "name":"CLOAM1160 Ornithine decarboxylase\tK01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]" } ] } ] }, { "name":"09107 Glycan biosynthesis and metabolism", "children":[ { "name":"00520 Amino sugar and nucleotide sugar metabolism [PATH:caci00520]", "children":[ { "name":"CLOAM0363 Bifunctional glmU protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase] (partial, glmU fragment)\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]" }, { "name":"CLOAM0675 wecB; UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]" }, { "name":"CLOAM1615 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"CLOAM1544 murB; UDP-N-acetylenolpyruvoylglucosamine reductase (UDP-N-acetylmuramate dehydrogenase)\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"CLOAM0691 UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase) (GalE-like)\tK02473 wbpP; UDP-N-acetylglucosamine\/UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimerase [EC:5.1.3.7 5.1.3.45]" }, { "name":"CLOAM0957 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (Hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"CLOAM1490 putative glutamine-fructose-6-phosphate transaminase [isomerizing] (glucosamine--fructose-6-phosphate aminotransferase)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"CLOAM1751 pgi; Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"CLOAM1580 putative mannose-6-phosphate isomerase\tK01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]" }, { "name":"CLOAM1376 putative Glucokinase (Glucose kinase) (glcK-like)\tK25026 glk; glucokinase [EC:2.7.1.2]" }, { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM1098 putative glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"CLOAM1468 ugd; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"CLOAM1469 galE; UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase)\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"CLOAM1012 Phosphoglucomutase\/phosphomannomutase family protein\tK01840 manB; phosphomannomutase [EC:5.4.2.8]" }, { "name":"CLOAM0349 mannose-1-phosphate guanylyltransferase\/mannose-6-phosphate isomerase,truncation\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]" }, { "name":"CLOAM0663 GDP-mannose 6-dehydrogenase (GMD)\tK00066 algD; GDP-mannose 6-dehydrogenase [EC:1.1.1.132]" }, { "name":"CLOAM0642 Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase)\tK00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]" } ] }, { "name":"00541 Biosynthesis of various nucleotide sugars [PATH:caci00541]", "children":[ { "name":"CLOAM0363 Bifunctional glmU protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase] (partial, glmU fragment)\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]" }, { "name":"CLOAM0691 UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase) (GalE-like)\tK02473 wbpP; UDP-N-acetylglucosamine\/UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimerase [EC:5.1.3.7 5.1.3.45]" }, { "name":"CLOAM1565 mviM; predicted dehydrogenase and related proteins\tK13020 wlbA; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335]" }, { "name":"CLOAM1218 wecB; UDP-N-acetylglucosamine 2-epimerase\tK13019 wbpI; UDP-GlcNAc3NAcA epimerase [EC:5.1.3.23]" }, { "name":"CLOAM0743 carbohydrate isomerase, KpsF\/GutQ family\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]" }, { "name":"CLOAM1765 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]" }, { "name":"CLOAM1764 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]" }, { "name":"CLOAM1795 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]" }, { "name":"CLOAM0675 wecB; UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]" }, { "name":"CLOAM1702 gmhA; phosphoheptose isomerase\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]" }, { "name":"CLOAM1177 gmbH; D,D-heptose 1,7-bisphosphate phosphatase\tK03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]" }, { "name":"CLOAM0368 Carbohydrate kinase, PfkB\tK21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]" }, { "name":"CLOAM0367 Glycerol-3-phosphate cytidyltransferase\tK21345 rfaE2; D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase [EC:2.7.7.70]" }, { "name":"CLOAM1098 putative glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"CLOAM1468 ugd; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"CLOAM0642 Glucose-1-phosphate cytidylyltransferase (CDP-glucose pyrophosphorylase)\tK00978 rfbF; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33]" }, { "name":"CLOAM0643 CDP-glucose 4,6-dehydratase\tK01709 rfbG; CDP-glucose 4,6-dehydratase [EC:4.2.1.45]" }, { "name":"CLOAM0645 Lipopolysaccharide biosynthesis protein rfbH\tK12452 ascC; CDP-4-dehydro-6-deoxyglucose reductase, E1 [EC:1.17.1.1]" }, { "name":"CLOAM0279 rffG; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"CLOAM0644 putative dTDP-6-deoxy-D-glucose-3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"CLOAM0349 mannose-1-phosphate guanylyltransferase\/mannose-6-phosphate isomerase,truncation\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]" } ] }, { "name":"00510 N-Glycan biosynthesis" }, { "name":"00513 Various types of N-glycan biosynthesis" }, { "name":"00512 Mucin type O-glycan biosynthesis" }, { "name":"00515 Mannose type O-glycan biosynthesis" }, { "name":"00514 Other types of O-glycan biosynthesis" }, { "name":"00532 Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate" }, { "name":"00534 Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin" }, { "name":"00533 Glycosaminoglycan biosynthesis - keratan sulfate" }, { "name":"00531 Glycosaminoglycan degradation" }, { "name":"00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" }, { "name":"00601 Glycosphingolipid biosynthesis - lacto and neolacto series" }, { "name":"00603 Glycosphingolipid biosynthesis - globo and isoglobo series" }, { "name":"00604 Glycosphingolipid biosynthesis - ganglio series" }, { "name":"00511 Other glycan degradation" }, { "name":"00540 Lipopolysaccharide biosynthesis [PATH:caci00540]", "children":[ { "name":"CLOAM1380 lpxA; UDP-N-acetylglucosamine acetyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" }, { "name":"CLOAM1381 lpxC_fabZ; LpxC\/fabZ bifunctional enzyme [Includes: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase)]\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]" }, { "name":"CLOAM1382 lpxD; UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]" }, { "name":"CLOAM1417 putative UDP-2,3-diacylglucosamine hydrolase (lpxH-like)\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]" }, { "name":"CLOAM1069 putative lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]" }, { "name":"CLOAM0762 putative tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]" }, { "name":"CLOAM0901 putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase)\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]" }, { "name":"CLOAM1049 putative Lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]" }, { "name":"CLOAM0418 putative ADP-heptose:LPS heptosyltransferase II\tK02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]" } ] }, { "name":"00542 O-Antigen repeat unit biosynthesis [PATH:caci00542]", "children":[ { "name":"CLOAM0554 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM0636 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00550 Peptidoglycan biosynthesis [PATH:caci00550]", "children":[ { "name":"CLOAM1615 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"CLOAM1544 murB; UDP-N-acetylenolpyruvoylglucosamine reductase (UDP-N-acetylmuramate dehydrogenase)\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"CLOAM0781 murC; UDP-N-acetylmuramate--L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase)\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]" }, { "name":"CLOAM0784 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase) (D-glutamic acid adding enzyme)\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"CLOAM1339 ddlB; D-alanine--D-alanine ligase (D-alanylalanine synthetase) (D-Ala-D-Ala ligase)\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"CLOAM0786 putative bifunctional MurE\/MurF enzyme [Includes: UDP-N-acetylmuramoylalanyl-D-glutamate--2; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase)] (partial match,murE\/murF-like)\tK15792 murEF; MurE\/MurF fusion protein [EC:6.3.2.13 6.3.2.10]" }, { "name":"CLOAM1574 ispU; Undecaprenyl pyrophosphate synthetase (UPP synthetase) (Di-trans,poly-cis-decaprenylcistransferase) (Undecaprenyl diphosphate synthase) (UDS)\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" }, { "name":"CLOAM1041 putative undecaprenyl pyrophosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"CLOAM0785 mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase (UDP-MurNAc-pentapeptide phosphotransferase)\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"CLOAM0782 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase)\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" }, { "name":"CLOAM0934 Monofunctional biosynthetic peptidoglycan transglycosylase (Monofunctional TGase) (fragment)\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1238 mrcA; penicillin-binding bifunctional protein 1A (PBP-1a) (PBP1a) [Includes: penicillin-insensitive transglycosylase (peptidoglycan TGase); penicillin-sensitive transpeptidase (DD-transpeptidase)]\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"CLOAM0783 ftsW; Essential cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1802 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1803 mrdA; Penicillin-binding protein 2 (PBP-2)\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" } ] }, { "name":"00552 Teichoic acid biosynthesis [PATH:caci00552]", "children":[ { "name":"CLOAM1041 putative undecaprenyl pyrophosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"CLOAM0554 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM0636 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00571 Lipoarabinomannan (LAM) biosynthesis" }, { "name":"00572 Arabinogalactan biosynthesis - Mycobacterium", "children":[ { "name":"CLOAM0554 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM0636 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00543 Exopolysaccharide biosynthesis [PATH:caci00543]", "children":[ { "name":"CLOAM0554 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM0636 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM1579 Alginate O-acetylation protein\tK19294 algI; alginate O-acetyltransferase complex protein AlgI" } ] } ] }, { "name":"09108 Metabolism of cofactors and vitamins", "children":[ { "name":"00730 Thiamine metabolism [PATH:caci00730]", "children":[ { "name":"CLOAM1487 Conserved hypothetical protein; putative ThiF domain\tK03148 thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73]" }, { "name":"CLOAM1691 iscS; Cysteine desulfurase (ThiI transpersulfidase) (NifS protein homolog)\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"CLOAM0921 hydG; Fe-hydrogenase assembly protein,S-adenosylmethionine radical protein\tK03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19]" }, { "name":"CLOAM0157 dxs; 1-deoxy-D-xylulose-5-phosphate synthase (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]" }, { "name":"CLOAM0034 putative GTPase YjeQ\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]" }, { "name":"CLOAM0118 putative Thiamine pyrophosphokinase (TPK) (Thiamine diphosphokinase) (thiN-like)\tK00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2]" }, { "name":"CLOAM1458 adk; Adenylate kinase (ATP-AMP transphosphorylase)\tK00939 adk; adenylate kinase [EC:2.7.4.3]" } ] }, { "name":"00740 Riboflavin metabolism [PATH:caci00740]", "children":[ { "name":"CLOAM1453 ribA; 3,4-dihydroxy-2-butanone 4-phosphate synthase\/GTP cyclohydrolase II\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"CLOAM1819 ribD; riboflavin biosynthesis protein RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]" }, { "name":"CLOAM1423 ribE; riboflavin synthase beta chain\tK00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]" }, { "name":"CLOAM0451 putative riboflavin synthase, alpha subunit\tK00793 ribE; riboflavin synthase [EC:2.5.1.9]" }, { "name":"CLOAM0270 ribF; Riboflavin biosynthesis protein [Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)]\tK11753 ribF; riboflavin kinase \/ FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]" } ] }, { "name":"00750 Vitamin B6 metabolism [PATH:caci00750]", "children":[ { "name":"CLOAM0285 pdxK; Pyridoxine kinase (Pyridoxal kinase) (Vitamin B6 kinase) (Pyridoxamine kinase) (PN\/PL\/PM kinase)\tK00868 pdxK; pyridoxine kinase [EC:2.7.1.35]" }, { "name":"CLOAM0992 serC; phosphoserine aminotransferase (PSAT) (phosphoserine transaminase)\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" }, { "name":"CLOAM0719 putative threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" } ] }, { "name":"00760 Nicotinate and nicotinamide metabolism [PATH:caci00760]", "children":[ { "name":"CLOAM0357 putative NADH-dependent fumarate reductase (frd)\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]" }, { "name":"CLOAM0328 nadA; quinolinate synthetase\tK03517 nadA; quinolinate synthase [EC:2.5.1.72]" }, { "name":"CLOAM1857 nadC; nicotinate-nucleotide pyrophosphorylase\tK00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]" }, { "name":"CLOAM0405 Purine nucleoside phosphorylase 1 (Purine nucleoside phosphorylase I) (PNP I) (PU-NPase I) (Inosine phosphorylase)\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]" }, { "name":"CLOAM0524 putative 5'-nucleotidase\tK11751 ushA; 5'-nucleotidase \/ UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]" }, { "name":"CLOAM1168 surE; broad specificity 5'(3')-nucleotidase and polyphosphatase\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]" }, { "name":"CLOAM0053 putative nicotinate (nicotinamide) nucleotide adenylyltransferase\tK00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]" }, { "name":"CLOAM0890 npdA; NAD-dependent deacetylase (Regulatory protein SIR2 homolog)\tK12410 cobB; NAD-dependent protein deacetylase\/lipoamidase [EC:2.3.1.286 2.3.1.313]" }, { "name":"CLOAM0035 putative inorganic polyphosphate\/ATP-NAD kinase (Poly(P)\/ATP NAD kinase) (modular protein)\tK00858 ppnK; NAD+ kinase [EC:2.7.1.23]" } ] }, { "name":"00770 Pantothenate and CoA biosynthesis [PATH:caci00770]", "children":[ { "name":"CLOAM1642 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase)\tK00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]" }, { "name":"CLOAM1082 panC; Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate activating enzyme)\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]" }, { "name":"CLOAM1150 putative Pantothenate kinase type III (PanK,CoaX)\tK03525 coaX; type III pantothenate kinase [EC:2.7.1.33]" }, { "name":"CLOAM1437 dfp; Coenzyme A biosynthesis bifunctional protein coaBC (DNA\/pantothenate metabolism flavoprotein) [Includes: Phosphopantothenoylcysteine decarboxylase (PPCDC) (CoaC); Phosphopantothenate--cysteine ligase (Phosphopantothenoylcysteine synthase) (PPC synthetase) (PPCS) (CoaB)]\tK13038 coaBC; phosphopantothenoylcysteine decarboxylase \/ phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]" }, { "name":"CLOAM1088 coaD; Phosphopantetheine adenylyltransferase (Pantetheine-phosphate adenylyltransferase) (PPAT) (Dephospho-CoA pyrophosphorylase)\tK00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]" }, { "name":"CLOAM0986 coaE; Dephospho-CoA kinase (Dephosphocoenzyme A kinase)\tK00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]" }, { "name":"CLOAM1460 acpS; Holo-[acyl-carrier-protein] synthase (Holo-ACP synthase) (4'-phosphopantetheinyl transferase acpS)\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]" }, { "name":"CLOAM1631 putative dihydropyrimidine dehydrogenase [NADP+] (DPD) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase) (pydA)\tK00207 DPYD; dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]" }, { "name":"CLOAM1081 panD; Aspartate 1-decarboxylase precursor (Aspartate alpha-decarboxylase)\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]" } ] }, { "name":"00780 Biotin metabolism [PATH:caci00780]", "children":[ { "name":"CLOAM0251 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"CLOAM0253 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0682 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0690 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0448 hydEF; Fe-hydrogenase assembly protein (partial,N-terminal), S-adenosylmethionine(SAM) radical protein\tK01012 bioB; biotin synthase [EC:2.8.1.6]" }, { "name":"CLOAM1441 putative biotin ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]" }, { "name":"CLOAM1164 8-amino-7-oxononanoate synthase (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase)\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]" } ] }, { "name":"00785 Lipoic acid metabolism [PATH:caci00785]", "children":[ { "name":"CLOAM0056 lplA; Lipoate-protein ligase A\tK03800 lplA; lipoate---protein ligase [EC:6.3.1.20]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM1385 gcvPA; glycine dehydrogenase [decarboxylating] subunit 1 (Glycine decarboxylase subunit 1) (Glycine cleavage system P-protein subunit 1)\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]" }, { "name":"CLOAM1384 gcvPB; glycine dehydrogenase [decarboxylating] subunit 2 (Glycine decarboxylase subunit 2) (Glycine cleavage system P-protein subunit 2)\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]" }, { "name":"CLOAM1023 gcvT; aminomethyltransferase (Glycine cleavage system T protein)\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"CLOAM0290 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" } ] }, { "name":"00790 Folate biosynthesis [PATH:caci00790]", "children":[ { "name":"CLOAM0916 conserved hypothetical protein\tK09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16]" }, { "name":"CLOAM0365 folB; Dihydroneopterin aldolase (DHNA)\tK01633 folB; 7,8-dihydroneopterin aldolase\/epimerase\/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]" }, { "name":"CLOAM0988 folP; Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase)\tK00796 folP; dihydropteroate synthase [EC:2.5.1.15]" }, { "name":"CLOAM1093 folA; Dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]" }, { "name":"CLOAM1707 folC; FolC bifunctional protein [Includes: Folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase); Dihydrofolate synthase]\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]" }, { "name":"CLOAM1453 ribA; 3,4-dihydroxy-2-butanone 4-phosphate synthase\/GTP cyclohydrolase II\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"CLOAM1792 6-pyruvoyl tetrahydrobiopterin synthase family protein\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"CLOAM1484 Radical SAM\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]" }, { "name":"CLOAM0922 exsB protein\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]" } ] }, { "name":"00670 One carbon pool by folate [PATH:caci00670]", "children":[ { "name":"CLOAM1093 folA; Dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]" }, { "name":"CLOAM0539 folD; FolD bifunctional protein [Includes: Methylenetetrahydrofolate dehydrogenase; Methenyltetrahydrofolate cyclohydrolase]\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]" }, { "name":"CLOAM0752 glyA; serine hydroxymethyltransferase (serine methylase) (SHMT)\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"CLOAM1541 purN; phosphoribosylglycinamide formyltransferase (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]" }, { "name":"CLOAM1899 purH; Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"CLOAM0177 ftcd; Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (Formiminotetrahydrofolate cyclodeaminase)]\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" }, { "name":"CLOAM1023 gcvT; aminomethyltransferase (Glycine cleavage system T protein)\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"CLOAM1766 metK; S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT)\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"CLOAM1471 ahcY; S-adenosyl-L-homocysteine hydrolase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"CLOAM1385 gcvPA; glycine dehydrogenase [decarboxylating] subunit 1 (Glycine decarboxylase subunit 1) (Glycine cleavage system P-protein subunit 1)\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]" }, { "name":"CLOAM1384 gcvPB; glycine dehydrogenase [decarboxylating] subunit 2 (Glycine decarboxylase subunit 2) (Glycine cleavage system P-protein subunit 2)\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM0290 gcvH; Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein" } ] }, { "name":"00830 Retinol metabolism" }, { "name":"00860 Porphyrin metabolism" }, { "name":"00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:caci00130]", "children":[ { "name":"CLOAM1666 wrbA; putative conserved flavoprotein\tK03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]" } ] } ] }, { "name":"09109 Metabolism of terpenoids and polyketides", "children":[ { "name":"00900 Terpenoid backbone biosynthesis [PATH:caci00900]", "children":[ { "name":"CLOAM0157 dxs; 1-deoxy-D-xylulose-5-phosphate synthase (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS)\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]" }, { "name":"CLOAM1853 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomerase)\tK00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]" }, { "name":"CLOAM1491 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT)\tK00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]" }, { "name":"CLOAM0435 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase)\tK00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]" }, { "name":"CLOAM1489 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS) (MECDP-synthase)\tK01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]" }, { "name":"CLOAM0381 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase)\tK03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"CLOAM0326 ispA; Geranylgeranyl pyrophosphate synthetase homolog (GGPP synthetase) (Farnesyltranstransferase)\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"CLOAM1320 putative geranyltranstransferase\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"CLOAM1574 ispU; Undecaprenyl pyrophosphate synthetase (UPP synthetase) (Di-trans,poly-cis-decaprenylcistransferase) (Undecaprenyl diphosphate synthase) (UDS)\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" } ] }, { "name":"00902 Monoterpenoid biosynthesis" }, { "name":"00909 Sesquiterpenoid and triterpenoid biosynthesis" }, { "name":"00904 Diterpenoid biosynthesis" }, { "name":"00906 Carotenoid biosynthesis" }, { "name":"00905 Brassinosteroid biosynthesis" }, { "name":"00981 Insect hormone biosynthesis" }, { "name":"00908 Zeatin biosynthesis" }, { "name":"00903 Limonene degradation" }, { "name":"00907 Pinene, camphor and geraniol degradation" }, { "name":"01052 Type I polyketide structures" }, { "name":"00522 Biosynthesis of 12-, 14- and 16-membered macrolides" }, { "name":"01051 Biosynthesis of ansamycins", "children":[ { "name":"CLOAM1259 putative Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" } ] }, { "name":"01059 Biosynthesis of enediyne antibiotics" }, { "name":"01056 Biosynthesis of type II polyketide backbone" }, { "name":"01057 Biosynthesis of type II polyketide products" }, { "name":"00253 Tetracycline biosynthesis" }, { "name":"00523 Polyketide sugar unit biosynthesis [PATH:caci00523]", "children":[ { "name":"CLOAM0279 rffG; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"CLOAM0644 putative dTDP-6-deoxy-D-glucose-3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" } ] }, { "name":"01054 Nonribosomal peptide structures" }, { "name":"01053 Biosynthesis of siderophore group nonribosomal peptides" }, { "name":"01055 Biosynthesis of vancomycin group antibiotics", "children":[ { "name":"CLOAM0279 rffG; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" } ] } ] }, { "name":"09110 Biosynthesis of other secondary metabolites", "children":[ { "name":"00940 Phenylpropanoid biosynthesis" }, { "name":"00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis" }, { "name":"00941 Flavonoid biosynthesis" }, { "name":"00944 Flavone and flavonol biosynthesis" }, { "name":"00942 Anthocyanin biosynthesis" }, { "name":"00943 Isoflavonoid biosynthesis" }, { "name":"00946 Degradation of flavonoids" }, { "name":"00901 Indole alkaloid biosynthesis" }, { "name":"00403 Indole diterpene alkaloid biosynthesis" }, { "name":"00950 Isoquinoline alkaloid biosynthesis" }, { "name":"00960 Tropane, piperidine and pyridine alkaloid biosynthesis" }, { "name":"00996 Biosynthesis of various alkaloids" }, { "name":"00232 Caffeine metabolism" }, { "name":"00965 Betalain biosynthesis" }, { "name":"00966 Glucosinolate biosynthesis" }, { "name":"00402 Benzoxazinoid biosynthesis" }, { "name":"00311 Penicillin and cephalosporin biosynthesis" }, { "name":"00332 Carbapenem biosynthesis" }, { "name":"00261 Monobactam biosynthesis [PATH:caci00261]", "children":[ { "name":"CLOAM0441 lysC; Aspartokinase 2 (Aspartokinase II) (Aspartate kinase 2) [Contains: Aspartokinase II alpha subunit; Aspartokinase II beta subunit]\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"CLOAM0633 asd; Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH)\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"CLOAM0032 dapA; dihydrodipicolinate synthase (DHDPS)\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]" }, { "name":"CLOAM0281 dapB; dihydrodipicolinate reductase (DHPR)\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]" } ] }, { "name":"00331 Clavulanic acid biosynthesis" }, { "name":"00521 Streptomycin biosynthesis [PATH:caci00521]", "children":[ { "name":"CLOAM1376 putative Glucokinase (Glucose kinase) (glcK-like)\tK25026 glk; glucokinase [EC:2.7.1.2]" }, { "name":"CLOAM0516 cpsG; Phosphomannomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"CLOAM0423 ino1; Inositol-3-phosphate synthase (Myo-inositol-1-phosphate synthase) (MI-1-P synthase) (IPS)\tK01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]" }, { "name":"CLOAM0279 rffG; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"CLOAM0644 putative dTDP-6-deoxy-D-glucose-3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" } ] }, { "name":"00524 Neomycin, kanamycin and gentamicin biosynthesis", "children":[ { "name":"CLOAM1376 putative Glucokinase (Glucose kinase) (glcK-like)\tK25026 glk; glucokinase [EC:2.7.1.2]" } ] }, { "name":"00525 Acarbose and validamycin biosynthesis", "children":[ { "name":"CLOAM0279 rffG; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" } ] }, { "name":"00401 Novobiocin biosynthesis [PATH:caci00401]", "children":[ { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM0138 putative aromatic amino acid aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" } ] }, { "name":"00404 Staurosporine biosynthesis" }, { "name":"00405 Phenazine biosynthesis" }, { "name":"00333 Prodigiosin biosynthesis", "children":[ { "name":"CLOAM0254 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"CLOAM0253 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0682 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0690 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" } ] }, { "name":"00254 Aflatoxin biosynthesis" }, { "name":"00975 Biosynthesis of various siderophores" }, { "name":"00998 Biosynthesis of various antibiotics", "children":[ { "name":"CLOAM0252 acpP; Acyl carrier protein (ACP)\tK02078 acpP; acyl carrier protein" }, { "name":"CLOAM0680 putative acyl carrier protein (acpP-like)\tK02078 acpP; acyl carrier protein" } ] }, { "name":"00999 Biosynthesis of various plant secondary metabolites", "children":[ { "name":"CLOAM1766 metK; S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT)\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" } ] }, { "name":"00997 Biosynthesis of various other secondary metabolites" } ] }, { "name":"09111 Xenobiotics biodegradation and metabolism", "children":[ { "name":"00362 Benzoate degradation [PATH:caci00362]", "children":[ { "name":"CLOAM1513 putative Na+-transporting methylmalonyl-CoA\/oxaloacetate decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM1771 putative S-Methylmalonyl-CoA decarboxylase,sodium-translocating subunit, beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00627 Aminobenzoate degradation [PATH:caci00627]", "children":[ { "name":"CLOAM0741 putative acylphosphatase (Acylphosphate phosphohydrolase)\tK01512 acyP; acylphosphatase [EC:3.6.1.7]" }, { "name":"CLOAM0042 atoD; Acetoacetate:butyrate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]" }, { "name":"CLOAM0043 atoA; Acetoacetate:butyrate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]" } ] }, { "name":"00364 Fluorobenzoate degradation" }, { "name":"00625 Chloroalkane and chloroalkene degradation" }, { "name":"00361 Chlorocyclohexane and chlorobenzene degradation" }, { "name":"00623 Toluene degradation" }, { "name":"00622 Xylene degradation" }, { "name":"00633 Nitrotoluene degradation" }, { "name":"00642 Ethylbenzene degradation" }, { "name":"00643 Styrene degradation" }, { "name":"00791 Atrazine degradation" }, { "name":"00930 Caprolactam degradation" }, { "name":"00363 Bisphenol degradation" }, { "name":"00621 Dioxin degradation" }, { "name":"00626 Naphthalene degradation" }, { "name":"00624 Polycyclic aromatic hydrocarbon degradation" }, { "name":"00365 Furfural degradation" }, { "name":"00984 Steroid degradation" }, { "name":"00980 Metabolism of xenobiotics by cytochrome P450" }, { "name":"00982 Drug metabolism - cytochrome P450" }, { "name":"00983 Drug metabolism - other enzymes" } ] }, { "name":"09112 Not included in regular maps", "children":[ { "name":"09113 Global maps only" } ] } ] }, { "name":"09120 Genetic Information Processing", "children":[ { "name":"09121 Transcription", "children":[ { "name":"03020 RNA polymerase [PATH:caci03020]", "children":[ { "name":"CLOAM0456 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"CLOAM0455 rpoC; RNA polymerase, beta' subunit; binds Zn(II)\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"CLOAM1113 rpoA; DNA-directed RNA polymerase alpha chain (RNAP alpha subunit) (Transcriptase alpha chain) (RNA polymerase alpha subunit)\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" } ] }, { "name":"03022 Basal transcription factors" }, { "name":"03040 Spliceosome" } ] }, { "name":"09122 Translation", "children":[ { "name":"03010 Ribosome [PATH:caci03010]", "children":[ { "name":"CLOAM_23s_1 ribosomal RNA 23s\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"CLOAM_23s_2 ribosomal RNA 23s\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"CLOAM_5s_1 ribosomal RNA 5s\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"CLOAM_5s_2 ribosomal RNA 5s\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"CLOAM1220 30S ribosomal subunit protein S1 (modular protein)\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"CLOAM1687 putative Ribosomal protein S1\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"CLOAM1890 rpsB; 30S ribosomal subunit protein S2\tK02967 RP-S2; small subunit ribosomal protein S2" }, { "name":"CLOAM1134 rpsC; 30S ribosomal subunit protein S3\tK02982 RP-S3; small subunit ribosomal protein S3" }, { "name":"CLOAM1114 rpsD; 30S ribosomal subunit protein S4\tK02986 RP-S4; small subunit ribosomal protein S4" }, { "name":"CLOAM1123 rpsE; 30S ribosomal subunit protein S5\tK02988 RP-S5; small subunit ribosomal protein S5" }, { "name":"CLOAM1610 rpsF; 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6" }, { "name":"CLOAM0453 rpsG; 30S ribosomal subunit protein S7\tK02992 RP-S7; small subunit ribosomal protein S7" }, { "name":"CLOAM1126 rpsH; 30S ribosomal subunit protein S8\tK02994 RP-S8; small subunit ribosomal protein S8" }, { "name":"CLOAM1893 rpsI; 30S ribosomal subunit protein S9\tK02996 RP-S9; small subunit ribosomal protein S9" }, { "name":"CLOAM1141 rpsJ; 30S ribosomal subunit protein S10\tK02946 RP-S10; small subunit ribosomal protein S10" }, { "name":"CLOAM1115 rpsK; 30S ribosomal subunit protein S11\tK02948 RP-S11; small subunit ribosomal protein S11" }, { "name":"CLOAM0454 rpsL; 30S ribosomal subunit protein S12\tK02950 RP-S12; small subunit ribosomal protein S12" }, { "name":"CLOAM1116 rpsM; 30S ribosomal subunit protein S13\tK02952 RP-S13; small subunit ribosomal protein S13" }, { "name":"CLOAM1127 rpsN; ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"CLOAM1474 rpsO; 30S ribosomal subunit protein S15\tK02956 RP-S15; small subunit ribosomal protein S15" }, { "name":"CLOAM1467 rpsP; Ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16" }, { "name":"CLOAM1131 rpsQ; 30S ribosomal subunit protein S17\tK02961 RP-S17; small subunit ribosomal protein S17" }, { "name":"CLOAM1608 rpsR; 30S ribosomal subunit protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"CLOAM1136 rpsS; 30S ribosomal subunit protein S19\tK02965 RP-S19; small subunit ribosomal protein S19" }, { "name":"CLOAM0933 rpsT; 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20" }, { "name":"CLOAM1822 rpsU; 30S ribosomal subunit protein S21\tK02970 RP-S21; small subunit ribosomal protein S21" }, { "name":"CLOAM0459 rplA; 50S ribosomal subunit protein L1\tK02863 RP-L1; large subunit ribosomal protein L1" }, { "name":"CLOAM1137 rplB; 50S ribosomal subunit protein L2\tK02886 RP-L2; large subunit ribosomal protein L2" }, { "name":"CLOAM1140 rplC; 50S ribosomal subunit protein L3\tK02906 RP-L3; large subunit ribosomal protein L3" }, { "name":"CLOAM1139 rplD; 50S ribosomal protein L4\tK02926 RP-L4; large subunit ribosomal protein L4" }, { "name":"CLOAM1128 rplE; 50S ribosomal subunit protein L5\tK02931 RP-L5; large subunit ribosomal protein L5" }, { "name":"CLOAM1125 rplF; 50S ribosomal subunit protein L6\tK02933 RP-L6; large subunit ribosomal protein L6" }, { "name":"CLOAM1606 rplI; ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9" }, { "name":"CLOAM0458 rplJ; ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10" }, { "name":"CLOAM0460 rplK; 50S ribosomal subunit protein L11\tK02867 RP-L11; large subunit ribosomal protein L11" }, { "name":"CLOAM0457 rplL; 50S ribosomal subunit protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12" }, { "name":"CLOAM1894 rplM; 50S ribosomal subunit protein L13\tK02871 RP-L13; large subunit ribosomal protein L13" }, { "name":"CLOAM1130 rplN; 50S ribosomal subunit protein L14\tK02874 RP-L14; large subunit ribosomal protein L14" }, { "name":"CLOAM1121 rplO; 50S ribosomal subunit protein L15\tK02876 RP-L15; large subunit ribosomal protein L15" }, { "name":"CLOAM1133 rplP; 50S ribosomal subunit protein L16\tK02878 RP-L16; large subunit ribosomal protein L16" }, { "name":"CLOAM1112 rplQ; 50S ribosomal subunit protein L17\tK02879 RP-L17; large subunit ribosomal protein L17" }, { "name":"CLOAM1124 rplR; 50S ribosomal subunit protein L18\tK02881 RP-L18; large subunit ribosomal protein L18" }, { "name":"CLOAM1462 rplS; 50S ribosomal subunit protein L19\tK02884 RP-L19; large subunit ribosomal protein L19" }, { "name":"CLOAM0531 rplT; 50S ribosomal subunit protein L20\tK02887 RP-L20; large subunit ribosomal protein L20" }, { "name":"CLOAM0293 rplU; 50S ribosomal subunit protein L21\tK02888 RP-L21; large subunit ribosomal protein L21" }, { "name":"CLOAM1135 rplV; 50S ribosomal subunit protein L22\tK02890 RP-L22; large subunit ribosomal protein L22" }, { "name":"CLOAM1138 rplW; 50S ribosomal subunit protein L23\tK02892 RP-L23; large subunit ribosomal protein L23" }, { "name":"CLOAM1129 rplX; ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24" }, { "name":"CLOAM1612 rplY; ribosoma protein L25\tK02897 RP-L25; large subunit ribosomal protein L25" }, { "name":"CLOAM0292 rpmA; 50S ribosomal subunit protein L27\tK02899 RP-L27; large subunit ribosomal protein L27" }, { "name":"CLOAM1411 rpmB; ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"CLOAM1132 rpmC; ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29" }, { "name":"CLOAM1122 rpmD; 50S ribosomal subunit protein L30\tK02907 RP-L30; large subunit ribosomal protein L30" }, { "name":"CLOAM0173 rpmE; 50S ribosomal subunit protein L31\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"CLOAM0257 rpmF; ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32" }, { "name":"CLOAM0463 rpmG; ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"CLOAM0547 rpmH; 50S ribosomal subunit protein L34\tK02914 RP-L34; large subunit ribosomal protein L34" }, { "name":"CLOAM0530 rpmI; 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35" }, { "name":"CLOAM1117 rpmJ; 50S ribosomal subunit protein L36\tK02919 RP-L36; large subunit ribosomal protein L36" } ] }, { "name":"00970 Aminoacyl-tRNA biosynthesis [PATH:caci00970]", "children":[ { "name":"CLOAMtRNA28 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"CLOAMtRNA29 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"CLOAMtRNA46 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"CLOAMtRNA23 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA26 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA6 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA8 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA16 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn" }, { "name":"CLOAMtRNA10 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp" }, { "name":"CLOAMtRNA35 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys" }, { "name":"CLOAMtRNA3 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"CLOAMtRNA4 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"CLOAMtRNA44 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"CLOAMtRNA45 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"CLOAMtRNA32 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA34 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA37 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA40 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA27 tRNA-His\tK14226 tRNA-His; tRNA His" }, { "name":"CLOAMtRNA22 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"CLOAMtRNA11 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA12 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA13 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA33 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA36 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA21 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"CLOAMtRNA43 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"CLOAMtRNA20 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA24 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA25 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA5 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe" }, { "name":"CLOAMtRNA14 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"CLOAMtRNA30 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"CLOAMtRNA7 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"CLOAMtRNA1 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA17 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA2 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA31 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA38 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"CLOAMtRNA41 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"CLOAMtRNA9 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"CLOAMtRNA42 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp" }, { "name":"CLOAMtRNA39 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr" }, { "name":"CLOAMtRNA15 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"CLOAMtRNA18 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"CLOAMtRNA19 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"CLOAM0997 gltX; Glutamyl-tRNA synthetase (Glutamate--tRNA ligase) (GluRS)\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]" }, { "name":"CLOAM1207 glnS; glutamyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"CLOAM1696 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"CLOAM1540 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"CLOAM0728 Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase) (AsnRS)\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]" }, { "name":"CLOAM0316 glyQ; glycine tRNA synthetase, alpha subunit\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"CLOAM0616 putative glycine tRNA synthetase, beta subunit\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"CLOAM0744 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"CLOAM1669 serS; seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"CLOAM0734 cysS; cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"CLOAM0440 Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS)\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"CLOAM0008 fmt; methionyl-tRNA formyltransferase\tK00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]" }, { "name":"CLOAM0259 valS; valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"CLOAM1110 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"CLOAM0569 Isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase) (IleRS)\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"CLOAM1688 lysS; lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"CLOAM0359 Arginyl-tRNA synthetase 1 (Arginine--tRNA ligase 1) (ArgRS 1)\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"CLOAM0426 Prolyl-tRNA synthetase 2 (Proline--tRNA ligase 2) (ProRS 2)\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"CLOAM0335 putative Histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"CLOAM0515 hisS; histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"CLOAM0533 pheS; phenylalanine tRNA synthetase, alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"CLOAM0534 pheT; phenylalanyl-tRNA synthetase, beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"CLOAM0627 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"CLOAM1432 Tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" } ] }, { "name":"03013 Nucleocytoplasmic transport" }, { "name":"03015 mRNA surveillance pathway" }, { "name":"03008 Ribosome biogenesis in eukaryotes", "children":[ { "name":"CLOAM0250 rnc; dsRNA-specific ribonuclease\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" } ] } ] }, { "name":"09123 Folding, sorting and degradation", "children":[ { "name":"03060 Protein export [PATH:caci03060]", "children":[ { "name":"CLOAM1120 secY; preprotein translocase secY subunit, essential membrane protein\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"CLOAM0462 secE; Preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"CLOAM1170 secG; protein-export membrane protein secG, essential membrane protein\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"CLOAM1010 secD; protein-export membrane protein secD, accessory membrane protein\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"CLOAM1009 secF; protein-export membrane protein secF, accessory membrane protein\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"CLOAM0006 yajC; Preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"CLOAM0544 Preprotein translocase subunit YidC (modular protein)\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"CLOAM1732 secA; preprotein translocase secA subunit, essential ATPase protein\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"CLOAM1602 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"CLOAM0799 ftsY; Cell division protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"CLOAM1675 putative signal peptidase I (lepB)\tK03100 lepB; signal peptidase I [EC:3.4.21.89]" }, { "name":"CLOAM0407 Signal peptidase II\tK03101 lspA; signal peptidase II [EC:3.4.23.36]" } ] }, { "name":"04141 Protein processing in endoplasmic reticulum [PATH:caci04141]", "children":[ { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"CLOAM0112 putative Molecular chaperone (small heat shock protein)\tK13993 HSP20; HSP20 family protein" }, { "name":"CLOAM1852 hypothetical protein\tK13993 HSP20; HSP20 family protein" } ] }, { "name":"04130 SNARE interactions in vesicular transport" }, { "name":"04120 Ubiquitin mediated proteolysis" }, { "name":"04122 Sulfur relay system [PATH:caci04122]", "children":[ { "name":"CLOAM1691 iscS; Cysteine desulfurase (ThiI transpersulfidase) (NifS protein homolog)\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"CLOAM0896 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase \/ fibronectin\/fibrinogen-binding protein\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"CLOAM1161 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"CLOAM1487 Conserved hypothetical protein; putative ThiF domain\tK03148 thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73]" } ] }, { "name":"03050 Proteasome" }, { "name":"03018 RNA degradation [PATH:caci03018]", "children":[ { "name":"CLOAM1651 eno; enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"CLOAM1473 pnp; polynucleotide phosphorylase\/polyadenylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"CLOAM0909 putative ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]" }, { "name":"CLOAM0952 rho; transcription termination factor\tK03628 rho; transcription termination factor Rho" }, { "name":"CLOAM0537 KH domain\/HD domain protein\tK18682 rny; ribonucrease Y [EC:3.1.-.-]" }, { "name":"CLOAM0757 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"CLOAM1649 groL; Cpn60 chaperonin GroEL, large subunit of GroESL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" } ] } ] }, { "name":"09124 Replication and repair", "children":[ { "name":"03030 DNA replication [PATH:caci03030]", "children":[ { "name":"CLOAM1746 dnaE; DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"CLOAM1210 DNA polymerase III, gamma\/tau subunits (fragment)\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"CLOAM0793 putative DNA polymerase III, delta prime subunit (holB-like)\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"CLOAM1040 putative DNA polymerase III, delta subunit (holA-like)\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"CLOAM1536 putative DNA polymerase III, beta chain (dnaN-like)\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"CLOAM1089 dnaB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]" }, { "name":"CLOAM1825 dnaG; DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]" }, { "name":"CLOAM1609 Single-stranded DNA-binding protein (modular protein)\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"CLOAM1007 rnhB; ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]" }, { "name":"CLOAM1706 putative Ribonuclease H\tK03471 rnhC; ribonuclease HIII [EC:3.1.26.4]" }, { "name":"CLOAM0968 ligA; DNA ligase, NAD-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03410 Base excision repair [PATH:caci03410]", "children":[ { "name":"CLOAM0039 putative endonuclease III (nth-like)\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"CLOAM1877 putative formamidopyrimidine\/5-formyluracil\/5-hydroxymethyluracil DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"CLOAM0287 ung; Uracil-DNA glycosylase\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"CLOAM1175 xthA; Exonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"CLOAM0321 putative ssDNA exonuclease, 5'--> 3'-specific\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM1265 hypothetical protein\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM0968 ligA; DNA ligase, NAD-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03420 Nucleotide excision repair [PATH:caci03420]", "children":[ { "name":"CLOAM0548 putative transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"CLOAM0971 uvrA; ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"CLOAM0820 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component\tK03702 uvrB; excinuclease ABC subunit B" }, { "name":"CLOAM0765 hypothetical protein\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"CLOAM0791 Excinuclease ABC, C subunit\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"CLOAM0486 conserved hypothetical protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"CLOAM0549 uvrD; Superfamily I DNA and RNA helicases\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"CLOAM0968 ligA; DNA ligase, NAD-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03430 Mismatch repair [PATH:caci03430]", "children":[ { "name":"CLOAM0950 DNA mismatch repair protein\tK03555 mutS; DNA mismatch repair protein MutS" }, { "name":"CLOAM0391 hypothetical protein\tK07456 mutS2; DNA mismatch repair protein MutS2" }, { "name":"CLOAM1824 putative recombination and DNA strand exchange inhibitor protein\tK07456 mutS2; DNA mismatch repair protein MutS2" }, { "name":"CLOAM1302 mutL; DNA mismatch repair protein MutL\tK03572 mutL; DNA mismatch repair protein MutL" }, { "name":"CLOAM0486 conserved hypothetical protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"CLOAM0549 uvrD; Superfamily I DNA and RNA helicases\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"CLOAM0245 xseA; Exonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]" }, { "name":"CLOAM0325 xseB; Exonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]" }, { "name":"CLOAM0321 putative ssDNA exonuclease, 5'--> 3'-specific\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM1265 hypothetical protein\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM1609 Single-stranded DNA-binding protein (modular protein)\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"CLOAM1746 dnaE; DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"CLOAM1536 putative DNA polymerase III, beta chain (dnaN-like)\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"CLOAM1210 DNA polymerase III, gamma\/tau subunits (fragment)\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"CLOAM1040 putative DNA polymerase III, delta subunit (holA-like)\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"CLOAM0793 putative DNA polymerase III, delta prime subunit (holB-like)\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"CLOAM0968 ligA; DNA ligase, NAD-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" }, { "name":"CLOAM0203 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0204 N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0502 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0503 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM1327 Modification methylase MjaIII (Adenine-specific methyltransferase MjaIII) (M.MjaIII)\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" } ] }, { "name":"03440 Homologous recombination [PATH:caci03440]", "children":[ { "name":"CLOAM0321 putative ssDNA exonuclease, 5'--> 3'-specific\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM1265 hypothetical protein\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM1609 Single-stranded DNA-binding protein (modular protein)\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"CLOAM1537 putative putative DNA repair and genetic recombination (recF-like)\tK03629 recF; DNA replication and repair protein RecF" }, { "name":"CLOAM1059 hypothetical protein\tK03584 recO; DNA repair protein RecO (recombination protein O)" }, { "name":"CLOAM0450 recR; recombination protein RecR\tK06187 recR; recombination protein RecR" }, { "name":"CLOAM1869 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA" }, { "name":"CLOAM0929 ruvA; Holliday junction DNA helicase RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA" }, { "name":"CLOAM1679 ruvB; Holliday junction helicase, subunit B\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]" }, { "name":"CLOAM0930 ruvC; crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]" }, { "name":"CLOAM1698 recG; ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"CLOAM1746 dnaE; DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"CLOAM1536 putative DNA polymerase III, beta chain (dnaN-like)\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"CLOAM1210 DNA polymerase III, gamma\/tau subunits (fragment)\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"CLOAM1040 putative DNA polymerase III, delta subunit (holA-like)\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"CLOAM0793 putative DNA polymerase III, delta prime subunit (holB-like)\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"CLOAM0274 Primosomal protein n\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]" } ] }, { "name":"03450 Non-homologous end-joining" }, { "name":"03460 Fanconi anemia pathway" } ] }, { "name":"09126 Chromosome", "children":[ { "name":"03082 ATP-dependent chromatin remodeling" }, { "name":"03083 Polycomb repressive complex" } ] }, { "name":"09125 Information processing in viruses", "children":[ { "name":"03230 Viral genome structure" }, { "name":"03240 Viral replication" }, { "name":"03250 Viral life cycle - HIV-1" }, { "name":"03260 Virion - Human immunodeficiency virus" }, { "name":"03271 Virion - Rotavirus" }, { "name":"03262 Virion - Coronavirus" }, { "name":"03261 Virion - Influenza virus" }, { "name":"03263 Virion - Enterovirus" }, { "name":"03264 Virion - Flavivirus and Alphavirus" }, { "name":"03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus" }, { "name":"03273 Virion - Lassa virus and SFTS virus" }, { "name":"03272 Virion - Hepatitis viruses" }, { "name":"03266 Virion - Herpesvirus" }, { "name":"03268 Virion - Orthopoxvirus" }, { "name":"03267 Virion - Adenovirus" }, { "name":"03259 Virion - Bacteriophages T4 and T7" }, { "name":"03258 Virion - Bacteriophage lambda" } ] } ] }, { "name":"09130 Environmental Information Processing", "children":[ { "name":"09131 Membrane transport", "children":[ { "name":"02010 ABC transporters [PATH:caci02010]", "children":[ { "name":"CLOAM1091 hypothetical protein\tK02064 thiB; thiamine transport system substrate-binding protein" }, { "name":"CLOAM1539 potD; spermidine\/putrescine-binding periplasmic protein precursor (SPBP)\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein" }, { "name":"CLOAM0766 potC; Spermidine\/putrescine transport system permease protein potC (ABC transporter)\tK11070 potC; spermidine\/putrescine transport system permease protein" }, { "name":"CLOAM0767 potB; Spermidine\/putrescine transport system permease protein potB (ABC transporter)\tK11071 potB; spermidine\/putrescine transport system permease protein" }, { "name":"CLOAM0768 potA; Spermidine\/putrescine import ATP-binding protein potA (ABC transporter)\tK11072 potA; spermidine\/putrescine transport system ATP-binding protein [EC:7.6.2.11]" }, { "name":"CLOAM1845 ycjV; putative sugar transporter subunit: ATP-binding component of ABC superfamily transporter\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]" }, { "name":"CLOAM0133 hypothetical protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"CLOAM0169 hypothetical protein; putative signal peptide\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"CLOAM1097 hypothetical protein; putative signal peptide\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"CLOAM1090 conserved hypothetical protein; putative membrane protein\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"CLOAM1095 transporter, putative (modular protein)\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"CLOAM1374 hypothetical protein; putative membrane protein\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"CLOAM1094 ABC transporter, ATP-binding protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"CLOAM1236 ABC transporter, ATP-binding protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"CLOAM1373 hypothetical protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"CLOAM1518 Phosphonates-binding protein\tK02044 phnD; phosphonate transport system substrate-binding protein" }, { "name":"CLOAM1644 ABC-type phosphonates transport system permease protein precursor\tK02042 phnE; phosphonate transport system permease protein" }, { "name":"CLOAM1519 phnC; phosphonate\/organophosphate ester transporter subunit; ATP-binding component of ABC superfamily\tK02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]" }, { "name":"CLOAM0130 znuA; ABC-type Mn\/Zn transport system, periplasmic Mn\/Zn-binding (lipo)protein (surface adhesin A)\tK09815 znuA; zinc transport system substrate-binding protein" }, { "name":"CLOAM0128 ABC transporter, permease protein\tK09816 znuB; zinc transport system permease protein" }, { "name":"CLOAM0129 ABC transporter, ATP-binding protein\tK09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]" }, { "name":"CLOAM1354 Putative cobalt transport system permease protein (ABC transporter) (cbiQ-like)\tK16785 ecfT; energy-coupling factor transport system permease protein" }, { "name":"CLOAM0956 hypothetical protein; putative membrane protein\tK09696 natB; sodium transport system permease protein" }, { "name":"CLOAM0955 ccmA; ABC-type multidrug transport system, ATPase component\tK09697 natA; sodium transport system ATP-binding protein [EC:7.2.2.4]" }, { "name":"CLOAM0143 hypothetical protein; putative membrane protein\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"CLOAM1268 hypothetical protein; putative membrane protein\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"CLOAM1269 ABC transporter, ATP-binding protein\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]" }, { "name":"CLOAM0967 putative Permease YjgP\/YjgQ\tK07091 lptF; lipopolysaccharide export system permease protein" }, { "name":"CLOAM0966 putative Permease\tK11720 lptG; lipopolysaccharide export system permease protein" }, { "name":"CLOAM1759 lptB; putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]" }, { "name":"CLOAM0412 ABC transporter, ATP-binding protein, MsbA family (modular protein)\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"CLOAM1019 putative ABC transporter, transmembrane region:ABC transporter related\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"CLOAM1522 mdlB; ABC-type multidrug\/protein\/lipid transport system, ATPase component\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"CLOAM1020 putative ABC transporter (membrane (N-terminal),atp_bind (C-terminal))\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"CLOAM1521 ABC transporter, transmembrane region:ABC transporter related\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump" } ] }, { "name":"02060 Phosphotransferase system (PTS) [PATH:caci02060]", "children":[ { "name":"CLOAM1752 putative PEP-protein phosphotransferase of PTS system (enzyme I)\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]" }, { "name":"CLOAM1753 ptsH; phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr" }, { "name":"CLOAM0343 hypothetical protein\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]" } ] }, { "name":"03070 Bacterial secretion system [PATH:caci03070]", "children":[ { "name":"CLOAM0087 hypothetical protein; putative signal peptide\tK12340 tolC; outer membrane protein" }, { "name":"CLOAM1010 secD; protein-export membrane protein secD, accessory membrane protein\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"CLOAM1009 secF; protein-export membrane protein secF, accessory membrane protein\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"CLOAM0462 secE; Preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"CLOAM1170 secG; protein-export membrane protein secG, essential membrane protein\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"CLOAM1120 secY; preprotein translocase secY subunit, essential membrane protein\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"CLOAM0006 yajC; Preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"CLOAM0544 Preprotein translocase subunit YidC (modular protein)\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"CLOAM1732 secA; preprotein translocase secA subunit, essential ATPase protein\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"CLOAM0799 ftsY; Cell division protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"CLOAM1602 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" } ] } ] }, { "name":"09132 Signal transduction", "children":[ { "name":"02020 Two-component system [PATH:caci02020]", "children":[ { "name":"CLOAM0010 protease degQ (fragment)\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM1866 degQ; protease degQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM0001 dnaA; chromosomal replication initiation protein\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"CLOAM1714 mae; NAD-dependent malic enzyme (NAD-ME)\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]" }, { "name":"CLOAM0663 GDP-mannose 6-dehydrogenase (GMD)\tK00066 algD; GDP-mannose 6-dehydrogenase [EC:1.1.1.132]" }, { "name":"CLOAM0955 ccmA; ABC-type multidrug transport system, ATPase component\tK09697 natA; sodium transport system ATP-binding protein [EC:7.2.2.4]" }, { "name":"CLOAM0956 hypothetical protein; putative membrane protein\tK09696 natB; sodium transport system permease protein" }, { "name":"CLOAM0630 glnA; glutamine synthetase (glutamate--ammonia ligase)\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"CLOAM0876 putative sigma-54 dependent DNA-binding response regulator\tK13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX" }, { "name":"CLOAM0042 atoD; Acetoacetate:butyrate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]" }, { "name":"CLOAM0043 atoA; Acetoacetate:butyrate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"CLOAM1757 rpoN; RNA polymerase sigma-54 factor\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"CLOAM1401 putative Pilus biogenesis protein tapA precursor\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"CLOAM0087 hypothetical protein; putative signal peptide\tK12340 tolC; outer membrane protein" }, { "name":"CLOAM0675 wecB; UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]" } ] }, { "name":"04010 MAPK signaling pathway" }, { "name":"04013 MAPK signaling pathway - fly" }, { "name":"04016 MAPK signaling pathway - plant" }, { "name":"04011 MAPK signaling pathway - yeast" }, { "name":"04012 ErbB signaling pathway" }, { "name":"04014 Ras signaling pathway" }, { "name":"04015 Rap1 signaling pathway" }, { "name":"04310 Wnt signaling pathway" }, { "name":"04330 Notch signaling pathway" }, { "name":"04340 Hedgehog signaling pathway" }, { "name":"04341 Hedgehog signaling pathway - fly" }, { "name":"04350 TGF-beta signaling pathway" }, { "name":"04390 Hippo signaling pathway" }, { "name":"04391 Hippo signaling pathway - fly" }, { "name":"04392 Hippo signaling pathway - multiple species" }, { "name":"04370 VEGF signaling pathway" }, { "name":"04371 Apelin signaling pathway" }, { "name":"04630 JAK-STAT signaling pathway" }, { "name":"04064 NF-kappa B signaling pathway" }, { "name":"04668 TNF signaling pathway" }, { "name":"04066 HIF-1 signaling pathway" }, { "name":"04068 FoxO signaling pathway" }, { "name":"04020 Calcium signaling pathway" }, { "name":"04070 Phosphatidylinositol signaling system" }, { "name":"04072 Phospholipase D signaling pathway" }, { "name":"04071 Sphingolipid signaling pathway" }, { "name":"04024 cAMP signaling pathway" }, { "name":"04022 cGMP-PKG signaling pathway" }, { "name":"04151 PI3K-Akt signaling pathway" }, { "name":"04152 AMPK signaling pathway" }, { "name":"04150 mTOR signaling pathway" }, { "name":"04075 Plant hormone signal transduction" } ] }, { "name":"09133 Signaling molecules and interaction", "children":[ { "name":"04080 Neuroactive ligand-receptor interaction" }, { "name":"04082 Neuroactive ligand signaling" }, { "name":"04081 Hormone signaling" }, { "name":"04060 Cytokine-cytokine receptor interaction" }, { "name":"04061 Viral protein interaction with cytokine and cytokine receptor" }, { "name":"04512 ECM-receptor interaction" }, { "name":"04514 Cell adhesion molecule (CAM) interaction" }, { "name":"04517 IgSF CAM signaling" }, { "name":"04518 Integrin signaling" }, { "name":"04519 Cadherin signaling" } ] } ] }, { "name":"09140 Cellular Processes", "children":[ { "name":"09141 Transport and catabolism", "children":[ { "name":"04144 Endocytosis" }, { "name":"04145 Phagocytosis" }, { "name":"04142 Lysosome biogenesis" }, { "name":"04146 Peroxisome" }, { "name":"04149 Peroxisome - yeast" }, { "name":"04140 Autophagy - animal" }, { "name":"04138 Autophagy - yeast" }, { "name":"04136 Autophagy - other" }, { "name":"04137 Mitophagy - animal" }, { "name":"04139 Mitophagy - yeast" }, { "name":"04148 Efferocytosis", "children":[ { "name":"CLOAM1160 Ornithine decarboxylase\tK01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]" } ] } ] }, { "name":"09143 Cell growth and death", "children":[ { "name":"04110 Cell cycle" }, { "name":"04111 Cell cycle - yeast" }, { "name":"04112 Cell cycle - Caulobacter" }, { "name":"04113 Meiosis - yeast" }, { "name":"04114 Oocyte meiosis" }, { "name":"04210 Apoptosis" }, { "name":"04214 Apoptosis - fly" }, { "name":"04215 Apoptosis - multiple species" }, { "name":"04216 Ferroptosis" }, { "name":"04217 Necroptosis" }, { "name":"04115 p53 signaling pathway" }, { "name":"04218 Cellular senescence" }, { "name":"04156 Integrated stress response (ISR) signaling pathway [PATH:caci04156]", "children":[ { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"CLOAMtRNA20 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA24 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA25 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAM0757 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"CLOAM1649 groL; Cpn60 chaperonin GroEL, large subunit of GroESL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" } ] } ] }, { "name":"09144 Cellular community - eukaryotes", "children":[ { "name":"04510 Focal adhesion" }, { "name":"04520 Adherens junction" }, { "name":"04530 Tight junction" }, { "name":"04540 Gap junction" }, { "name":"04550 Signaling pathways regulating pluripotency of stem cells" } ] }, { "name":"09145 Cellular community - prokaryotes", "children":[ { "name":"02024 Quorum sensing [PATH:caci02024]", "children":[ { "name":"CLOAM1819 ribD; riboflavin biosynthesis protein RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]" }, { "name":"CLOAM0544 Preprotein translocase subunit YidC (modular protein)\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"CLOAM0304 putative serine peptidase precursor; putative signal peptide\tK14645 K14645; serine protease [EC:3.4.21.-]" }, { "name":"CLOAM0462 secE; Preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"CLOAM1170 secG; protein-export membrane protein secG, essential membrane protein\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"CLOAM1120 secY; preprotein translocase secY subunit, essential membrane protein\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"CLOAM0006 yajC; Preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"CLOAM1732 secA; preprotein translocase secA subunit, essential ATPase protein\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"CLOAM0799 ftsY; Cell division protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"CLOAM1602 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" } ] }, { "name":"05111 Biofilm formation - Vibrio cholerae" }, { "name":"02025 Biofilm formation - Pseudomonas aeruginosa" }, { "name":"02026 Biofilm formation - Escherichia coli" } ] }, { "name":"09142 Cell motility", "children":[ { "name":"02030 Bacterial chemotaxis" }, { "name":"02040 Flagellar assembly [PATH:caci02040]", "children":[ { "name":"CLOAM0739 putative RNA polymerase, sigma S (sigma 38) factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"CLOAM1826 rpoD; RNA polymerase sigma factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"CLOAM1757 rpoN; RNA polymerase sigma-54 factor\tK03092 rpoN; RNA polymerase sigma-54 factor" } ] }, { "name":"04814 Motor proteins" }, { "name":"04820 Cytoskeleton in muscle cells", "children":[ { "name":"CLOAM1651 eno; enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" } ] }, { "name":"04810 Regulation of actin cytoskeleton" } ] } ] }, { "name":"09150 Organismal Systems", "children":[ { "name":"09151 Immune system", "children":[ { "name":"04640 Hematopoietic cell lineage" }, { "name":"04610 Complement and coagulation cascades" }, { "name":"04611 Platelet activation" }, { "name":"04613 Neutrophil extracellular trap formation" }, { "name":"04620 Toll-like receptor signaling pathway" }, { "name":"04624 Toll and Imd signaling pathway" }, { "name":"04621 NOD-like receptor signaling pathway" }, { "name":"04622 RIG-I-like receptor signaling pathway" }, { "name":"04623 Cytosolic DNA-sensing pathway" }, { "name":"04625 C-type lectin receptor signaling pathway" }, { "name":"04650 Natural killer cell mediated cytotoxicity" }, { "name":"04612 Antigen processing and presentation" }, { "name":"04660 T cell receptor signaling pathway" }, { "name":"04658 Th1 and Th2 cell differentiation" }, { "name":"04659 Th17 cell differentiation" }, { "name":"04657 IL-17 signaling pathway" }, { "name":"04662 B cell receptor signaling pathway" }, { "name":"04664 Fc epsilon RI signaling pathway" }, { "name":"04666 Fc gamma R-mediated phagosome formation" }, { "name":"04670 Leukocyte transendothelial migration" }, { "name":"04672 Intestinal immune network for IgA production" }, { "name":"04062 Chemokine signaling pathway" } ] }, { "name":"09152 Endocrine system", "children":[ { "name":"04911 Insulin secretion" }, { "name":"04910 Insulin signaling pathway" }, { "name":"04922 Glucagon signaling pathway" }, { "name":"04923 Regulation of lipolysis in adipocytes" }, { "name":"04920 Adipocytokine signaling pathway" }, { "name":"03320 PPAR signaling pathway" }, { "name":"04929 GnRH secretion" }, { "name":"04912 GnRH signaling pathway" }, { "name":"04913 Ovarian steroidogenesis" }, { "name":"04915 Estrogen signaling pathway" }, { "name":"04914 Progesterone-mediated oocyte maturation" }, { "name":"04917 Prolactin signaling pathway" }, { "name":"04921 Oxytocin signaling pathway" }, { "name":"04926 Relaxin signaling pathway" }, { "name":"04935 Growth hormone synthesis, secretion and action" }, { "name":"04918 Thyroid hormone synthesis" }, { "name":"04919 Thyroid hormone signaling pathway" }, { "name":"04928 Parathyroid hormone synthesis, secretion and action" }, { "name":"04916 Melanogenesis" }, { "name":"04924 Renin secretion" }, { "name":"04614 Renin-angiotensin system" }, { "name":"04925 Aldosterone synthesis and secretion" }, { "name":"04927 Cortisol synthesis and secretion" } ] }, { "name":"09153 Circulatory system", "children":[ { "name":"04260 Cardiac muscle contraction" }, { "name":"04261 Adrenergic signaling in cardiomyocytes" }, { "name":"04270 Vascular smooth muscle contraction" } ] }, { "name":"09154 Digestive system", "children":[ { "name":"04970 Salivary secretion" }, { "name":"04971 Gastric acid secretion" }, { "name":"04972 Pancreatic secretion" }, { "name":"04976 Bile secretion" }, { "name":"04973 Carbohydrate digestion and absorption" }, { "name":"04974 Protein digestion and absorption" }, { "name":"04975 Fat digestion and absorption" }, { "name":"04979 Cholesterol metabolism" }, { "name":"04977 Vitamin digestion and absorption" }, { "name":"04981 Folate transport and metabolism [PATH:caci04981]", "children":[ { "name":"CLOAM1093 folA; Dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]" }, { "name":"CLOAM0752 glyA; serine hydroxymethyltransferase (serine methylase) (SHMT)\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" } ] }, { "name":"04980 Cobalamin transport and metabolism [PATH:caci04980]", "children":[ { "name":"CLOAM0805 argK; ATPase\/kinase associated with arginine transport\tK07588 MMAA; GTPase [EC:3.6.5.-]" }, { "name":"CLOAM0803 mutA; Methylmalonyl-CoA mutase small subunit (MCM-beta)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"CLOAM0804 mutB; Methylmalonyl-CoA mutase large subunit (MCM-alpha)\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" } ] }, { "name":"04978 Mineral absorption" } ] }, { "name":"09155 Excretory system", "children":[ { "name":"04962 Vasopressin-regulated water reabsorption" }, { "name":"04960 Aldosterone-regulated sodium reabsorption" }, { "name":"04961 Endocrine and other factor-regulated calcium reabsorption" }, { "name":"04964 Proximal tubule bicarbonate reclamation" }, { "name":"04966 Collecting duct acid secretion" } ] }, { "name":"09156 Nervous system", "children":[ { "name":"04724 Glutamatergic synapse" }, { "name":"04727 GABAergic synapse" }, { "name":"04725 Cholinergic synapse" }, { "name":"04728 Dopaminergic synapse" }, { "name":"04726 Serotonergic synapse" }, { "name":"04720 Long-term potentiation" }, { "name":"04730 Long-term depression" }, { "name":"04723 Retrograde endocannabinoid signaling" }, { "name":"04721 Synaptic vesicle cycle" }, { "name":"04722 Neurotrophin signaling pathway" } ] }, { "name":"09157 Sensory system", "children":[ { "name":"04744 Phototransduction" }, { "name":"04745 Phototransduction - fly" }, { "name":"04740 Olfactory transduction" }, { "name":"04742 Taste transduction" }, { "name":"04750 Inflammatory mediator regulation of TRP channels" } ] }, { "name":"09158 Development and regeneration", "children":[ { "name":"04320 Dorso-ventral axis formation" }, { "name":"04360 Axon guidance" }, { "name":"04361 Axon regeneration" }, { "name":"04380 Osteoclast differentiation" }, { "name":"04382 Cornified envelope formation [PATH:caci04382]", "children":[ { "name":"CLOAM1164 8-amino-7-oxononanoate synthase (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase)\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]" }, { "name":"CLOAM0511 hutH; histidine ammonia-lyase (Histidase)\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]" } ] } ] }, { "name":"09149 Aging", "children":[ { "name":"04211 Longevity regulating pathway" }, { "name":"04212 Longevity regulating pathway - worm" }, { "name":"04213 Longevity regulating pathway - multiple species" } ] }, { "name":"09159 Environmental adaptation", "children":[ { "name":"04710 Circadian rhythm" }, { "name":"04713 Circadian entrainment" }, { "name":"04711 Circadian rhythm - fly" }, { "name":"04712 Circadian rhythm - plant" }, { "name":"04714 Thermogenesis" }, { "name":"04626 Plant-pathogen interaction" } ] } ] }, { "name":"09160 Human Diseases", "children":[ { "name":"09161 Cancer: overview", "children":[ { "name":"05200 Pathways in cancer" }, { "name":"05202 Transcriptional misregulation in cancer" }, { "name":"05206 MicroRNAs in cancer" }, { "name":"05205 Proteoglycans in cancer" }, { "name":"05204 Chemical carcinogenesis - DNA adducts" }, { "name":"05207 Chemical carcinogenesis - receptor activation" }, { "name":"05208 Chemical carcinogenesis - reactive oxygen species" }, { "name":"05203 Viral carcinogenesis" }, { "name":"05230 Central carbon metabolism in cancer" }, { "name":"05231 Choline metabolism in cancer" }, { "name":"05235 PD-L1 expression and PD-1 checkpoint pathway in cancer" } ] }, { "name":"09162 Cancer: specific types", "children":[ { "name":"05210 Colorectal cancer" }, { "name":"05212 Pancreatic cancer" }, { "name":"05225 Hepatocellular carcinoma" }, { "name":"05226 Gastric cancer" }, { "name":"05214 Glioma" }, { "name":"05216 Thyroid cancer" }, { "name":"05221 Acute myeloid leukemia" }, { "name":"05220 Chronic myeloid leukemia" }, { "name":"05217 Basal cell carcinoma" }, { "name":"05218 Melanoma" }, { "name":"05211 Renal cell carcinoma" }, { "name":"05219 Bladder cancer" }, { "name":"05215 Prostate cancer" }, { "name":"05213 Endometrial cancer" }, { "name":"05224 Breast cancer" }, { "name":"05222 Small cell lung cancer" }, { "name":"05223 Non-small cell lung cancer" } ] }, { "name":"09172 Infectious disease: viral", "children":[ { "name":"05166 Human T-cell leukemia virus 1 infection" }, { "name":"05170 Human immunodeficiency virus 1 infection" }, { "name":"05161 Hepatitis B" }, { "name":"05160 Hepatitis C" }, { "name":"05171 Coronavirus disease" }, { "name":"05164 Influenza A" }, { "name":"05162 Measles" }, { "name":"05168 Herpes simplex virus 1 infection" }, { "name":"05163 Human cytomegalovirus infection" }, { "name":"05167 Kaposi sarcoma-associated herpesvirus infection" }, { "name":"05169 Epstein-Barr virus infection" }, { "name":"05165 Human papillomavirus infection" } ] }, { "name":"09171 Infectious disease: bacterial", "children":[ { "name":"05110 Vibrio cholerae infection" }, { "name":"05120 Epithelial cell signaling in Helicobacter pylori infection" }, { "name":"05130 Pathogenic Escherichia coli infection" }, { "name":"05132 Salmonella infection" }, { "name":"05131 Shigellosis" }, { "name":"05135 Yersinia infection" }, { "name":"05133 Pertussis" }, { "name":"05134 Legionellosis" }, { "name":"05150 Staphylococcus aureus infection" }, { "name":"05152 Tuberculosis" }, { "name":"05100 Bacterial invasion of epithelial cells" } ] }, { "name":"09174 Infectious disease: parasitic", "children":[ { "name":"05146 Amoebiasis" }, { "name":"05144 Malaria" }, { "name":"05145 Toxoplasmosis" }, { "name":"05140 Leishmaniasis" }, { "name":"05142 Chagas disease" }, { "name":"05143 African trypanosomiasis" } ] }, { "name":"09163 Immune disease", "children":[ { "name":"05310 Asthma" }, { "name":"05322 Systemic lupus erythematosus" }, { "name":"05323 Rheumatoid arthritis" }, { "name":"05320 Autoimmune thyroid disease" }, { "name":"05321 Inflammatory bowel disease" }, { "name":"05330 Allograft rejection" }, { "name":"05332 Graft-versus-host disease" }, { "name":"05340 Primary immunodeficiency" } ] }, { "name":"09164 Neurodegenerative disease", "children":[ { "name":"05010 Alzheimer disease" }, { "name":"05012 Parkinson disease" }, { "name":"05014 Amyotrophic lateral sclerosis" }, { "name":"05016 Huntington disease" }, { "name":"05017 Spinocerebellar ataxia" }, { "name":"05020 Prion disease" }, { "name":"05022 Pathways of neurodegeneration - multiple diseases" } ] }, { "name":"09165 Substance dependence", "children":[ { "name":"05030 Cocaine addiction" }, { "name":"05031 Amphetamine addiction" }, { "name":"05032 Morphine addiction" }, { "name":"05033 Nicotine addiction" }, { "name":"05034 Alcoholism" } ] }, { "name":"09166 Cardiovascular disease", "children":[ { "name":"05417 Lipid and atherosclerosis" }, { "name":"05418 Fluid shear stress and atherosclerosis" }, { "name":"05410 Hypertrophic cardiomyopathy" }, { "name":"05412 Arrhythmogenic right ventricular cardiomyopathy" }, { "name":"05414 Dilated cardiomyopathy" }, { "name":"05415 Diabetic cardiomyopathy" }, { "name":"05416 Viral myocarditis" } ] }, { "name":"09167 Endocrine and metabolic disease", "children":[ { "name":"04930 Type II diabetes mellitus" }, { "name":"04940 Type I diabetes mellitus" }, { "name":"04950 Maturity onset diabetes of the young" }, { "name":"04936 Alcoholic liver disease" }, { "name":"04932 Non-alcoholic fatty liver disease" }, { "name":"04931 Insulin resistance" }, { "name":"04933 AGE-RAGE signaling pathway in diabetic complications" }, { "name":"04934 Cushing syndrome" } ] }, { "name":"09175 Drug resistance: antimicrobial", "children":[ { "name":"01501 beta-Lactam resistance [PATH:caci01501]", "children":[ { "name":"CLOAM1033 hypothetical protein; putative signal peptide\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"CLOAM1032 outer membrane efflux protein (fragment)\tK18138 acrB; multidrug efflux pump" }, { "name":"CLOAM0087 hypothetical protein; putative signal peptide\tK12340 tolC; outer membrane protein" }, { "name":"CLOAM1238 mrcA; penicillin-binding bifunctional protein 1A (PBP-1a) (PBP1a) [Includes: penicillin-insensitive transglycosylase (peptidoglycan TGase); penicillin-sensitive transpeptidase (DD-transpeptidase)]\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"CLOAM1803 mrdA; Penicillin-binding protein 2 (PBP-2)\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" } ] }, { "name":"01502 Vancomycin resistance [PATH:caci01502]", "children":[ { "name":"CLOAM1339 ddlB; D-alanine--D-alanine ligase (D-alanylalanine synthetase) (D-Ala-D-Ala ligase)\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"CLOAM0785 mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase (UDP-MurNAc-pentapeptide phosphotransferase)\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"CLOAM0782 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase)\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" } ] }, { "name":"01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:caci01503]", "children":[ { "name":"CLOAM1516 putative N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" }, { "name":"CLOAM0010 protease degQ (fragment)\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM1866 degQ; protease degQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM1033 hypothetical protein; putative signal peptide\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"CLOAM1032 outer membrane efflux protein (fragment)\tK18138 acrB; multidrug efflux pump" }, { "name":"CLOAM0087 hypothetical protein; putative signal peptide\tK12340 tolC; outer membrane protein" }, { "name":"CLOAM1380 lpxA; UDP-N-acetylglucosamine acetyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" } ] } ] }, { "name":"09176 Drug resistance: antineoplastic", "children":[ { "name":"01521 EGFR tyrosine kinase inhibitor resistance" }, { "name":"01524 Platinum drug resistance" }, { "name":"01523 Antifolate resistance" }, { "name":"01522 Endocrine resistance" } ] } ] }, { "name":"09180 Brite Hierarchies", "children":[ { "name":"09181 Protein families: metabolism", "children":[ { "name":"01000 Enzymes [BR:caci01000]" }, { "name":"01001 Protein kinases [BR:caci01001]", "children":[ { "name":"CLOAM0927 hypothetical protein\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"CLOAM1190 Anti-sigma regulatory factor (Ser\/Thr protein kinase) (modular protein)\tK17752 rsbT; serine\/threonine-protein kinase RsbT [EC:2.7.11.1]" }, { "name":"CLOAM0434 putative Non-specific protein-tyrosine kinase\tK16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]" } ] }, { "name":"01009 Protein phosphatases and associated proteins [BR:caci01009]", "children":[ { "name":"CLOAM1471 ahcY; S-adenosyl-L-homocysteine hydrolase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"CLOAM1722 hypothetical protein\tK20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]" } ] }, { "name":"01002 Peptidases and inhibitors [BR:caci01002]", "children":[ { "name":"CLOAM0407 Signal peptidase II\tK03101 lspA; signal peptidase II [EC:3.4.23.36]" }, { "name":"CLOAM0731 putative bifunctional prepilin leader peptidase and methylase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"CLOAM0898 guaA; GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]" }, { "name":"CLOAM0369 purF; amidophosphoribosyltransferase precursor (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (GPATase)\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" }, { "name":"CLOAM0957 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (Hexosephosphate aminotransferase) (D-fructose-6-phosphate amidotransferase) (GFAT) (L-glutamine-D-fructose-6-phosphate amidotransferase) (Glucosamine-6-phosphate synthase)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"CLOAM1490 putative glutamine-fructose-6-phosphate transaminase [isomerizing] (glucosamine--fructose-6-phosphate aminotransferase)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"CLOAM0669 putative Asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"CLOAM1585 asnB; asparagine synthetase (Glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"CLOAM0033 Peptidase M16, C-terminal:Peptidase M16,N-terminal\tK06972 PITRM1; presequence protease [EC:3.4.24.-]" }, { "name":"CLOAM0080 putative Peptidase, M16 family\tK07263 pqqL; zinc protease [EC:3.4.24.-]" }, { "name":"CLOAM0917 putative zinc protease (metalloendopeptidase) (ymxG module)\tK07263 pqqL; zinc protease [EC:3.4.24.-]" }, { "name":"CLOAM0131 pepA; cytosol aminopeptidase (leucine aminopeptidase) (LAP) (leucyl aminopeptidase) (aminopeptidase A\/I)\tK01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]" }, { "name":"CLOAM0280 putative peptidase T (tripeptide aminopeptidase) (aminotripeptidase) (tripeptidase) (yqjE)\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]" }, { "name":"CLOAM0632 putative Metal-dependent amidase\/aminoacylase\/carboxypeptidase\tK05823 dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]" }, { "name":"CLOAM1119 map; methionine aminopeptidase (MAP) (peptidase M)\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]" }, { "name":"CLOAM1087 pepP; Xaa-Pro aminopeptidase (X-Pro aminopeptidase) (aminopeptidase P II) (APP-II) (aminoacylproline aminopeptidase)\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]" }, { "name":"CLOAM1092 hypothetical protein\tK19689 ampS; aminopeptidase [EC:3.4.11.-]" }, { "name":"CLOAM0831 ftsH; Cell division protein FtsH, ATP-dependent zinc protease\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"CLOAM1145 htpX; Zn-dependent protease with chaperone function\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]" }, { "name":"CLOAM1502 putative zinc metallopeptidase\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]" }, { "name":"CLOAM0998 conserved hypothetical protein\tK16203 dppA1; D-amino peptidase [EC:3.4.11.-]" }, { "name":"CLOAM0010 protease degQ (fragment)\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM1866 degQ; protease degQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM0304 putative serine peptidase precursor; putative signal peptide\tK14645 K14645; serine protease [EC:3.4.21.-]" }, { "name":"CLOAM1085 clpP; proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]" }, { "name":"CLOAM1447 lon; DNA-binding ATP-dependent protease La; heat shock K-protein\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]" }, { "name":"CLOAM0975 Protein umuD [Contains: Protein umuD']\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]" }, { "name":"CLOAM1675 putative signal peptidase I (lepB)\tK03100 lepB; signal peptidase I [EC:3.4.21.89]" }, { "name":"CLOAM0355 ctpA; tail-specific protease precursor (carboxy-terminal processing protease precursor) (C-terminal processing peptidase)\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]" }, { "name":"CLOAM0188 putative Tricorn protease homolog\tK08676 tri; tricorn protease [EC:3.4.21.-]" }, { "name":"CLOAM0825 putative tricorn protease (tri); putative signal peptide\tK08676 tri; tricorn protease [EC:3.4.21.-]" }, { "name":"CLOAM1029 putative Acid phosphatase\tK04773 sppA; protease IV [EC:3.4.21.-]" }, { "name":"CLOAM1902 putative protease IV (signal peptide peptidase)\tK04773 sppA; protease IV [EC:3.4.21.-]" }, { "name":"CLOAM0830 hslV; peptidase component of the HslUV protease\tK01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]" }, { "name":"CLOAM0309 conserved hypothetical protein\tK03568 tldD; TldD protein" } ] }, { "name":"01003 Glycosyltransferases [BR:caci01003]", "children":[ { "name":"CLOAM1680 glycosyl transferase, group 2 family protein\tK00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]" }, { "name":"CLOAM0934 Monofunctional biosynthetic peptidoglycan transglycosylase (Monofunctional TGase) (fragment)\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1238 mrcA; penicillin-binding bifunctional protein 1A (PBP-1a) (PBP1a) [Includes: penicillin-insensitive transglycosylase (peptidoglycan TGase); penicillin-sensitive transpeptidase (DD-transpeptidase)]\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"CLOAM0783 ftsW; Essential cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1802 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM0554 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM0636 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"01005 Lipopolysaccharide biosynthesis proteins [BR:caci01005]", "children":[ { "name":"CLOAM1380 lpxA; UDP-N-acetylglucosamine acetyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" }, { "name":"CLOAM1069 putative lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]" }, { "name":"CLOAM1381 lpxC_fabZ; LpxC\/fabZ bifunctional enzyme [Includes: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase)]\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]" }, { "name":"CLOAM1382 lpxD; UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]" }, { "name":"CLOAM1417 putative UDP-2,3-diacylglucosamine hydrolase (lpxH-like)\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]" }, { "name":"CLOAM0762 putative tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]" }, { "name":"CLOAM1049 putative Lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]" }, { "name":"CLOAM0901 putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase)\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]" }, { "name":"CLOAM1765 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]" }, { "name":"CLOAM1795 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]" }, { "name":"CLOAM1764 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]" }, { "name":"CLOAM0743 carbohydrate isomerase, KpsF\/GutQ family\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]" }, { "name":"CLOAM0368 Carbohydrate kinase, PfkB\tK21344 rfaE1; D-glycero-beta-D-manno-heptose-7-phosphate kinase [EC:2.7.1.167]" }, { "name":"CLOAM0367 Glycerol-3-phosphate cytidyltransferase\tK21345 rfaE2; D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase [EC:2.7.7.70]" }, { "name":"CLOAM0418 putative ADP-heptose:LPS heptosyltransferase II\tK02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24]" }, { "name":"CLOAM1702 gmhA; phosphoheptose isomerase\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]" }, { "name":"CLOAM1177 gmbH; D,D-heptose 1,7-bisphosphate phosphatase\tK03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]" }, { "name":"CLOAM0554 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM0636 putative UDP-N-acetylmuramyl pentapeptide phosphotransferase\/UDP-N-acetylglucosamine-1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"CLOAM1566 putative UDP-N-acetylglucosamine 4-epimerase\tK19997 gnu; GlcNAc-P-P-Und epimerase [EC:5.1.3.26]" } ] }, { "name":"01011 Peptidoglycan biosynthesis and degradation proteins [BR:caci01011]", "children":[ { "name":"CLOAM1615 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT)\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"CLOAM1544 murB; UDP-N-acetylenolpyruvoylglucosamine reductase (UDP-N-acetylmuramate dehydrogenase)\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"CLOAM0781 murC; UDP-N-acetylmuramate--L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase)\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]" }, { "name":"CLOAM0784 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase) (D-glutamic acid adding enzyme)\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"CLOAM0786 putative bifunctional MurE\/MurF enzyme [Includes: UDP-N-acetylmuramoylalanyl-D-glutamate--2; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase)] (partial match,murE\/murF-like)\tK15792 murEF; MurE\/MurF fusion protein [EC:6.3.2.13 6.3.2.10]" }, { "name":"CLOAM1339 ddlB; D-alanine--D-alanine ligase (D-alanylalanine synthetase) (D-Ala-D-Ala ligase)\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"CLOAM0911 murI; Glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]" }, { "name":"CLOAM0785 mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase (UDP-MurNAc-pentapeptide phosphotransferase)\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"CLOAM0782 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase)\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" }, { "name":"CLOAM1041 putative undecaprenyl pyrophosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"CLOAM0792 conserved hypothetical protein; putative membrane protein\tK03980 murJ; putative peptidoglycan lipid II flippase" }, { "name":"CLOAM1238 mrcA; penicillin-binding bifunctional protein 1A (PBP-1a) (PBP1a) [Includes: penicillin-insensitive transglycosylase (peptidoglycan TGase); penicillin-sensitive transpeptidase (DD-transpeptidase)]\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"CLOAM1803 mrdA; Penicillin-binding protein 2 (PBP-2)\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" }, { "name":"CLOAM0934 Monofunctional biosynthetic peptidoglycan transglycosylase (Monofunctional TGase) (fragment)\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM0783 ftsW; Essential cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1802 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1709 putative Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM\/invasin domains)\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]" }, { "name":"CLOAM1508 predicted periplasmic solute-binding protein\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]" }, { "name":"CLOAM1000 hypothetical protein\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]" }, { "name":"CLOAM1516 putative N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" } ] }, { "name":"01004 Lipid biosynthesis proteins [BR:caci01004]", "children":[ { "name":"CLOAM0254 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"CLOAM0255 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"CLOAM0689 beta-ketoacyl-acyl carrier protein synthase (fabH-like)\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]" }, { "name":"CLOAM0251 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"CLOAM0253 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0682 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM0690 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"CLOAM1381 lpxC_fabZ; LpxC\/fabZ bifunctional enzyme [Includes: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase)]\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]" }, { "name":"CLOAM1438 putative beta-ketoacyl-acyl-carrier-protein reductase (fabG-like)\tK11610 mabA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-]" }, { "name":"CLOAM0256 plsX; fatty acid\/phospholipid synthesis protein,methyltransferase domain\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]" }, { "name":"CLOAM0162 hypothetical protein; putative membrane protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"CLOAM0370 conserved hypothetical protein; putative membrane protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]" }, { "name":"CLOAM1445 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase (1-AGP acyltransferase) (1-AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT) (plsC)\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" } ] }, { "name":"01008 Polyketide biosynthesis proteins" }, { "name":"01006 Prenyltransferases [BR:caci01006]", "children":[ { "name":"CLOAM0326 ispA; Geranylgeranyl pyrophosphate synthetase homolog (GGPP synthetase) (Farnesyltranstransferase)\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"CLOAM1320 putative geranyltranstransferase\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"CLOAM1574 ispU; Undecaprenyl pyrophosphate synthetase (UPP synthetase) (Di-trans,poly-cis-decaprenylcistransferase) (Undecaprenyl diphosphate synthase) (UDS)\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" }, { "name":"CLOAM1301 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]" } ] }, { "name":"01007 Amino acid related enzymes [BR:caci01007]", "children":[ { "name":"CLOAM1207 glnS; glutamyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"CLOAM0997 gltX; Glutamyl-tRNA synthetase (Glutamate--tRNA ligase) (GluRS)\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]" }, { "name":"CLOAM0627 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"CLOAM1432 Tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" }, { "name":"CLOAM0734 cysS; cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"CLOAM0359 Arginyl-tRNA synthetase 1 (Arginine--tRNA ligase 1) (ArgRS 1)\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"CLOAM0440 Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS)\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"CLOAM0569 Isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase) (IleRS)\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"CLOAM0259 valS; valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"CLOAM1110 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"CLOAM1688 lysS; lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"CLOAM1540 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"CLOAM0728 Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase) (AsnRS)\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]" }, { "name":"CLOAM0335 putative Histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"CLOAM0515 hisS; histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"CLOAM0316 glyQ; glycine tRNA synthetase, alpha subunit\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"CLOAM0616 putative glycine tRNA synthetase, beta subunit\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"CLOAM1669 serS; seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"CLOAM0426 Prolyl-tRNA synthetase 2 (Proline--tRNA ligase 2) (ProRS 2)\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"CLOAM0744 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"CLOAM1696 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"CLOAM0533 pheS; phenylalanine tRNA synthetase, alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"CLOAM0534 pheT; phenylalanyl-tRNA synthetase, beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"CLOAM0614 aspC; PLP-dependent aspartate aminotransferase (Transaminase A) (ASPAT) (class-I pyridoxal-phosphate-dependent aminotransferase)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM1245 putative alanine transaminase (class-I pyridoxal-phosphate-dependent aminotransferase) (alaT\/patA-like)\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"CLOAM0138 putative aromatic amino acid aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"CLOAM0960 kbl; glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]" }, { "name":"CLOAM1164 8-amino-7-oxononanoate synthase (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase)\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]" }, { "name":"CLOAM1025 class-II pyridoxal-phosphate-dependent aminotransferase (malY\/patB-like)\tK14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]" }, { "name":"CLOAM1147 putative ornithine\/acetylornithine\/succinyldiaminopimelate aminotransferase (ornithine\/acetylornithine\/succinyldiaminopimelate transaminase) (dapC-like)\tK00819 rocD; ornithine--oxo-acid transaminase [EC:2.6.1.13]" }, { "name":"CLOAM0992 serC; phosphoserine aminotransferase (PSAT) (phosphoserine transaminase)\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" } ] }, { "name":"00199 Cytochrome P450" }, { "name":"00194 Photosynthesis proteins" } ] }, { "name":"09182 Protein families: genetic information processing", "children":[ { "name":"03000 Transcription factors [BR:caci03000]", "children":[ { "name":"CLOAM1906 hypothetical protein\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator" }, { "name":"CLOAM0746 transcriptional regulator, ArsR family\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor" }, { "name":"CLOAM1441 putative biotin ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]" }, { "name":"CLOAM0278 parB-like domain protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"CLOAM0755 hypothetical protein\tK03705 hrcA; heat-inducible transcriptional repressor" }, { "name":"CLOAM1719 pyrR; Bifunctional protein : Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase (UPRTase)\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]" }, { "name":"CLOAM0790 mraZ; Protein MraZ\tK03925 mraZ; transcriptional regulator MraZ" } ] }, { "name":"03021 Transcription machinery [BR:caci03021]", "children":[ { "name":"CLOAM1113 rpoA; DNA-directed RNA polymerase alpha chain (RNAP alpha subunit) (Transcriptase alpha chain) (RNA polymerase alpha subunit)\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"CLOAM0456 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"CLOAM0455 rpoC; RNA polymerase, beta' subunit; binds Zn(II)\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"CLOAM0739 putative RNA polymerase, sigma S (sigma 38) factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"CLOAM1826 rpoD; RNA polymerase sigma factor\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"CLOAM1757 rpoN; RNA polymerase sigma-54 factor\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"CLOAM0263 nusA; transcription elongation factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA" }, { "name":"CLOAM1422 nusB; N utilization substance protein B\tK03625 nusB; transcription antitermination protein NusB" }, { "name":"CLOAM0461 nusG; transcription antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG" }, { "name":"CLOAM1190 Anti-sigma regulatory factor (Ser\/Thr protein kinase) (modular protein)\tK17752 rsbT; serine\/threonine-protein kinase RsbT [EC:2.7.11.1]" }, { "name":"CLOAM0366 conserved hypothetical protein\tK03803 rseC; sigma-E factor negative regulatory protein RseC" }, { "name":"CLOAM0049 putative transcription elongation factor\tK03624 greA; transcription elongation factor GreA" }, { "name":"CLOAM0952 rho; transcription termination factor\tK03628 rho; transcription termination factor Rho" } ] }, { "name":"03019 Messenger RNA biogenesis [BR:caci03019]", "children":[ { "name":"CLOAM1903 cafA; ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]" }, { "name":"CLOAM0250 rnc; dsRNA-specific ribonuclease\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"CLOAM0537 KH domain\/HD domain protein\tK18682 rny; ribonucrease Y [EC:3.1.-.-]" }, { "name":"CLOAM0909 putative ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]" }, { "name":"CLOAM0272 putative 3'-5' exoribonuclease yhaM\tK03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-]" }, { "name":"CLOAM1651 eno; enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"CLOAM1473 pnp; polynucleotide phosphorylase\/polyadenylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"CLOAM0952 rho; transcription termination factor\tK03628 rho; transcription termination factor Rho" }, { "name":"CLOAM0757 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"CLOAM1649 groL; Cpn60 chaperonin GroEL, large subunit of GroESL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" } ] }, { "name":"03041 Spliceosome" }, { "name":"03011 Ribosome [BR:caci03011]", "children":[ { "name":"CLOAM1220 30S ribosomal subunit protein S1 (modular protein)\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"CLOAM1687 putative Ribosomal protein S1\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"CLOAM1890 rpsB; 30S ribosomal subunit protein S2\tK02967 RP-S2; small subunit ribosomal protein S2" }, { "name":"CLOAM1134 rpsC; 30S ribosomal subunit protein S3\tK02982 RP-S3; small subunit ribosomal protein S3" }, { "name":"CLOAM1114 rpsD; 30S ribosomal subunit protein S4\tK02986 RP-S4; small subunit ribosomal protein S4" }, { "name":"CLOAM1123 rpsE; 30S ribosomal subunit protein S5\tK02988 RP-S5; small subunit ribosomal protein S5" }, { "name":"CLOAM1610 rpsF; 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6" }, { "name":"CLOAM0453 rpsG; 30S ribosomal subunit protein S7\tK02992 RP-S7; small subunit ribosomal protein S7" }, { "name":"CLOAM1126 rpsH; 30S ribosomal subunit protein S8\tK02994 RP-S8; small subunit ribosomal protein S8" }, { "name":"CLOAM1893 rpsI; 30S ribosomal subunit protein S9\tK02996 RP-S9; small subunit ribosomal protein S9" }, { "name":"CLOAM1141 rpsJ; 30S ribosomal subunit protein S10\tK02946 RP-S10; small subunit ribosomal protein S10" }, { "name":"CLOAM1115 rpsK; 30S ribosomal subunit protein S11\tK02948 RP-S11; small subunit ribosomal protein S11" }, { "name":"CLOAM0454 rpsL; 30S ribosomal subunit protein S12\tK02950 RP-S12; small subunit ribosomal protein S12" }, { "name":"CLOAM1116 rpsM; 30S ribosomal subunit protein S13\tK02952 RP-S13; small subunit ribosomal protein S13" }, { "name":"CLOAM1127 rpsN; ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"CLOAM1474 rpsO; 30S ribosomal subunit protein S15\tK02956 RP-S15; small subunit ribosomal protein S15" }, { "name":"CLOAM1467 rpsP; Ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16" }, { "name":"CLOAM1131 rpsQ; 30S ribosomal subunit protein S17\tK02961 RP-S17; small subunit ribosomal protein S17" }, { "name":"CLOAM1608 rpsR; 30S ribosomal subunit protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"CLOAM1136 rpsS; 30S ribosomal subunit protein S19\tK02965 RP-S19; small subunit ribosomal protein S19" }, { "name":"CLOAM0933 rpsT; 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20" }, { "name":"CLOAM1822 rpsU; 30S ribosomal subunit protein S21\tK02970 RP-S21; small subunit ribosomal protein S21" }, { "name":"CLOAM0459 rplA; 50S ribosomal subunit protein L1\tK02863 RP-L1; large subunit ribosomal protein L1" }, { "name":"CLOAM1137 rplB; 50S ribosomal subunit protein L2\tK02886 RP-L2; large subunit ribosomal protein L2" }, { "name":"CLOAM1140 rplC; 50S ribosomal subunit protein L3\tK02906 RP-L3; large subunit ribosomal protein L3" }, { "name":"CLOAM1139 rplD; 50S ribosomal protein L4\tK02926 RP-L4; large subunit ribosomal protein L4" }, { "name":"CLOAM1128 rplE; 50S ribosomal subunit protein L5\tK02931 RP-L5; large subunit ribosomal protein L5" }, { "name":"CLOAM1125 rplF; 50S ribosomal subunit protein L6\tK02933 RP-L6; large subunit ribosomal protein L6" }, { "name":"CLOAM1606 rplI; ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9" }, { "name":"CLOAM0458 rplJ; ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10" }, { "name":"CLOAM0460 rplK; 50S ribosomal subunit protein L11\tK02867 RP-L11; large subunit ribosomal protein L11" }, { "name":"CLOAM0457 rplL; 50S ribosomal subunit protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12" }, { "name":"CLOAM1894 rplM; 50S ribosomal subunit protein L13\tK02871 RP-L13; large subunit ribosomal protein L13" }, { "name":"CLOAM1130 rplN; 50S ribosomal subunit protein L14\tK02874 RP-L14; large subunit ribosomal protein L14" }, { "name":"CLOAM1121 rplO; 50S ribosomal subunit protein L15\tK02876 RP-L15; large subunit ribosomal protein L15" }, { "name":"CLOAM1133 rplP; 50S ribosomal subunit protein L16\tK02878 RP-L16; large subunit ribosomal protein L16" }, { "name":"CLOAM1112 rplQ; 50S ribosomal subunit protein L17\tK02879 RP-L17; large subunit ribosomal protein L17" }, { "name":"CLOAM1124 rplR; 50S ribosomal subunit protein L18\tK02881 RP-L18; large subunit ribosomal protein L18" }, { "name":"CLOAM1462 rplS; 50S ribosomal subunit protein L19\tK02884 RP-L19; large subunit ribosomal protein L19" }, { "name":"CLOAM0531 rplT; 50S ribosomal subunit protein L20\tK02887 RP-L20; large subunit ribosomal protein L20" }, { "name":"CLOAM0293 rplU; 50S ribosomal subunit protein L21\tK02888 RP-L21; large subunit ribosomal protein L21" }, { "name":"CLOAM1135 rplV; 50S ribosomal subunit protein L22\tK02890 RP-L22; large subunit ribosomal protein L22" }, { "name":"CLOAM1138 rplW; 50S ribosomal subunit protein L23\tK02892 RP-L23; large subunit ribosomal protein L23" }, { "name":"CLOAM1129 rplX; ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24" }, { "name":"CLOAM0292 rpmA; 50S ribosomal subunit protein L27\tK02899 RP-L27; large subunit ribosomal protein L27" }, { "name":"CLOAM1411 rpmB; ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"CLOAM1132 rpmC; ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29" }, { "name":"CLOAM1122 rpmD; 50S ribosomal subunit protein L30\tK02907 RP-L30; large subunit ribosomal protein L30" }, { "name":"CLOAM0173 rpmE; 50S ribosomal subunit protein L31\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"CLOAM0257 rpmF; ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32" }, { "name":"CLOAM0463 rpmG; ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"CLOAM0547 rpmH; 50S ribosomal subunit protein L34\tK02914 RP-L34; large subunit ribosomal protein L34" }, { "name":"CLOAM0530 rpmI; 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35" }, { "name":"CLOAM1117 rpmJ; 50S ribosomal subunit protein L36\tK02919 RP-L36; large subunit ribosomal protein L36" }, { "name":"CLOAM1612 rplY; ribosoma protein L25\tK02897 RP-L25; large subunit ribosomal protein L25" }, { "name":"CLOAM_23s_1 ribosomal RNA 23s\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"CLOAM_23s_2 ribosomal RNA 23s\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"CLOAM_5s_1 ribosomal RNA 5s\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"CLOAM_5s_2 ribosomal RNA 5s\tK01985 5SrRNA; 5S ribosomal RNA" } ] }, { "name":"03009 Ribosome biogenesis [BR:caci03009]", "children":[ { "name":"CLOAM0250 rnc; dsRNA-specific ribonuclease\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"CLOAM1148 era; GTP-binding protein Era\tK03595 era; GTPase" }, { "name":"CLOAM0122 obg; DNA-binding GTPase involved in cell partioning\tK03979 obgE; GTPase [EC:3.6.5.-]" }, { "name":"CLOAM0263 nusA; transcription elongation factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA" }, { "name":"CLOAM1422 nusB; N utilization substance protein B\tK03625 nusB; transcription antitermination protein NusB" }, { "name":"CLOAM0461 nusG; transcription antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG" }, { "name":"CLOAM1814 ksgA; Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (16S rRNA dimethylase) (High level kasugamycin resistance protein ksgA) (Kasugamycin dimethyltransferase)\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]" }, { "name":"CLOAM0928 putative 16S rRNA m5C967 methyltransferase,S-adenosyl-L-methionine-dependent\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]" }, { "name":"CLOAM0759 conserved hypothetical protein\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]" }, { "name":"CLOAM0276 putative S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division (gidB-like)\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]" }, { "name":"CLOAM0789 mraW; S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]" }, { "name":"CLOAM0961 predicted methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]" }, { "name":"CLOAM0737 conserved hypothetical protein\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]" }, { "name":"CLOAM1242 putative radical SAM-dependent enzyme (yfgB)\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]" }, { "name":"CLOAM1144 trmA; SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]" }, { "name":"CLOAM0345 rluB; ribosomal large subunit pseudouridine synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]" }, { "name":"CLOAM1454 rluA; Pseudouridylate synthase, 23S RNA-specific\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]" }, { "name":"CLOAM0358 putative Ribosomal-protein-alanine N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]" }, { "name":"CLOAM0625 putative Acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]" }, { "name":"CLOAM1465 hypothetical protein\tK02860 rimM; 16S rRNA processing protein RimM" }, { "name":"CLOAM1431 putative 2-alkenal reductase\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]" }, { "name":"CLOAM1903 cafA; ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]" }, { "name":"CLOAM1509 putative Holliday junction resolvase\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]" }, { "name":"CLOAM0034 putative GTPase YjeQ\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]" }, { "name":"CLOAM0371 engA; GTP-binding protein\tK03977 engA; GTPase" }, { "name":"CLOAM0044 hflX; GTPase\tK03665 hflX; GTPase" }, { "name":"CLOAM0267 putative ribosome-binding factor A (rbfA-like)\tK02834 rbfA; ribosome-binding factor A" }, { "name":"CLOAM0262 conserved hypothetical protein\tK09748 rimP; ribosome maturation factor RimP" }, { "name":"CLOAM0360 conserved hypothetical protein\tK09710 ybeB; ribosome-associated protein" }, { "name":"CLOAM1232 conserved hypothetical protein\tK07042 ybeY; probable rRNA maturation factor" }, { "name":"CLOAM1755 ribosome-associated, sigma 54 modulation protein (modular protein)\tK05808 hpf; ribosome hibernation promoting factor" }, { "name":"CLOAM0346 conserved hypothetical protein\tK06942 ychF; ribosome-binding ATPase" } ] }, { "name":"03016 Transfer RNA biogenesis [BR:caci03016]", "children":[ { "name":"CLOAM0553 hypothetical protein\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]" }, { "name":"CLOAM0426 Prolyl-tRNA synthetase 2 (Proline--tRNA ligase 2) (ProRS 2)\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"CLOAM0569 Isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase) (IleRS)\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"CLOAM1110 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"CLOAM0440 Methionyl-tRNA synthetase (Methionine--tRNA ligase) (MetRS)\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"CLOAM1207 glnS; glutamyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"CLOAM0359 Arginyl-tRNA synthetase 1 (Arginine--tRNA ligase 1) (ArgRS 1)\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"CLOAM1688 lysS; lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"CLOAM1540 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"CLOAM1696 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"CLOAM0728 Asparaginyl-tRNA synthetase (Asparagine--tRNA ligase) (AsnRS)\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]" }, { "name":"CLOAM0744 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"CLOAM1669 serS; seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"CLOAM0734 cysS; cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"CLOAM0259 valS; valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"CLOAM0335 putative Histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"CLOAM0515 hisS; histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"CLOAM0533 pheS; phenylalanine tRNA synthetase, alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"CLOAM0534 pheT; phenylalanyl-tRNA synthetase, beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"CLOAM0627 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"CLOAM1432 Tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" }, { "name":"CLOAM1800 dtd; D-tyrosyl-tRNA deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]" }, { "name":"CLOAM0906 miaB; tRNA-i(6)A37 modification enzyme MiaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]" }, { "name":"CLOAM1542 putative MiaB-like tRNA modifying enzyme\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]" }, { "name":"CLOAM0797 putative tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]" }, { "name":"CLOAM0514 putative pseudouridylate synthase I\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]" }, { "name":"CLOAM0269 truB; Pseudouridine synthase\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]" }, { "name":"CLOAM1691 iscS; Cysteine desulfurase (ThiI transpersulfidase) (NifS protein homolog)\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"CLOAM1301 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]" }, { "name":"CLOAM0156 trmE; tRNA modification GTPase trmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]" }, { "name":"CLOAM1794 gidA; glucose-inhibited division protein A\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme" }, { "name":"CLOAM0634 hypothetical protein\tK01147 rnb; exoribonuclease II [EC:3.1.13.1]" }, { "name":"CLOAM1870 conserved hypothetical protein\tK01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]" }, { "name":"CLOAM0316 glyQ; glycine tRNA synthetase, alpha subunit\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"CLOAM0616 putative glycine tRNA synthetase, beta subunit\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"CLOAM0997 gltX; Glutamyl-tRNA synthetase (Glutamate--tRNA ligase) (GluRS)\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]" }, { "name":"CLOAM0948 Cytosine\/adenosine deaminase\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]" }, { "name":"CLOAM0795 dihydrouridine synthase family protein\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]" }, { "name":"CLOAM1464 trmD; tRNA (guanine-1-)-methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]" }, { "name":"CLOAM0400 putative rRNA methylase\tK03437 spoU; RNA methyltransferase, TrmH family" }, { "name":"CLOAM0896 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase \/ fibronectin\/fibrinogen-binding protein\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"CLOAM1161 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"CLOAM1440 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]" }, { "name":"CLOAM0922 exsB protein\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]" }, { "name":"CLOAM1792 6-pyruvoyl tetrahydrobiopterin synthase family protein\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"CLOAM1484 Radical SAM\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]" }, { "name":"CLOAM1273 conserved hypothetical protein\tK09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]" }, { "name":"CLOAM1501 tgt; tRNA-guanine transglycosylase\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]" }, { "name":"CLOAM0833 putative tRNA(Ile)-lysidine synthase (tilS-like)\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]" }, { "name":"CLOAM1370 putative Peptidase M22, glycoprotease\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB" }, { "name":"CLOAM1638 predicted ATPase or kinase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE" }, { "name":"CLOAM0420 Putative Molybdenum cofactor biosynthesis protein (ygdL-like); putative ThiF domain\tK22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase" }, { "name":"CLOAM0909 putative ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]" }, { "name":"CLOAM1473 pnp; polynucleotide phosphorylase\/polyadenylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" } ] }, { "name":"03012 Translation factors [BR:caci03012]", "children":[ { "name":"CLOAM0266 infB; translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2" }, { "name":"CLOAM0529 infC; protein chain initiation factor IF-3\tK02520 infC; translation initiation factor IF-3" }, { "name":"CLOAM0528 putative fused ATP-binding subunits of ABC superfamily protein involved in precise excision of transposons\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3" }, { "name":"CLOAM1828 putative transporter fused subunits of ABC superfamily: ATP-binding components\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3" }, { "name":"CLOAM1889 tsf; elongation factor Ts\tK02357 tsf; elongation factor Ts" }, { "name":"CLOAM0464 tufB; protein chain elongation factor EF-Tu (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"CLOAM0932 fusA; translation elongation factor EF-G\tK02355 fusA; elongation factor G" }, { "name":"CLOAM1619 fusA-; translation elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"CLOAM0175 prfA; peptide chain release factor RF-1\tK02835 prfA; peptide chain release factor 1" }, { "name":"CLOAM1887 frr; ribosome recycling factor\tK02838 frr; ribosome recycling factor" }, { "name":"CLOAM1616 modification methylase, HemK family\tK02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]" }, { "name":"CLOAM1611 pth; peptidyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]" }, { "name":"CLOAM1118 infA; translation initiation factor IF-1\tK02518 infA; translation initiation factor IF-1" }, { "name":"CLOAM0572 efp; elongation factor P\tK02356 efp; elongation factor P" }, { "name":"CLOAM1575 prfB; Protein chain release factor B\tK02836 prfB; peptide chain release factor 2" } ] }, { "name":"03110 Chaperones and folding catalysts [BR:caci03110]", "children":[ { "name":"CLOAM0334 clpB; protein disaggregation chaperone\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB" }, { "name":"CLOAM1086 clpX; ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX" }, { "name":"CLOAM0829 hslU; molecular chaperone and ATPase component of HslUV protease\tK03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU" }, { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"CLOAM0757 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"CLOAM1649 groL; Cpn60 chaperonin GroEL, large subunit of GroESL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"CLOAM0758 dnaJ; Chaperone protein DnaJ (Heat shock protein 40) (HSP40)\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"CLOAM0438 putative chaperonin, 33 kDa family\tK04083 hslO; molecular chaperone Hsp33" }, { "name":"CLOAM0756 grpE; GrpE protein\tK03687 GRPE; molecular chaperone GrpE" }, { "name":"CLOAM0112 putative Molecular chaperone (small heat shock protein)\tK13993 HSP20; HSP20 family protein" }, { "name":"CLOAM1852 hypothetical protein\tK13993 HSP20; HSP20 family protein" }, { "name":"CLOAM0817 groES; chaperonin, 10 kDa\tK04078 groES; chaperonin GroES" }, { "name":"CLOAM0010 protease degQ (fragment)\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM1866 degQ; protease degQ\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"CLOAM0831 ftsH; Cell division protein FtsH, ATP-dependent zinc protease\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"CLOAM0304 putative serine peptidase precursor; putative signal peptide\tK14645 K14645; serine protease [EC:3.4.21.-]" }, { "name":"CLOAM0949 hypothetical protein; putative signal peptide\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]" }, { "name":"CLOAM1011 putative Peptidylprolyl isomerase\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]" }, { "name":"CLOAM0003 hypothetical protein; putative signal peptide\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]" }, { "name":"CLOAM1300 putative Parvulin-like peptidyl-prolyl isomerase\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]" }, { "name":"CLOAM0004 putative PpiC-type peptidyl-prolyl cis-trans isomerase precursor\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]" }, { "name":"CLOAM0816 trx; thioredoxin\tK03671 TXN; thioredoxin" }, { "name":"CLOAM0711 putative glutaredoxin\tK03676 grxC; glutaredoxin 3" } ] }, { "name":"04131 Membrane trafficking [BR:caci04131]", "children":[ { "name":"CLOAM0822 ndk; nucleoside diphosphate kinase (NDK) (NDP kinase) (nucleoside-2-P kinase)\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"CLOAM1530 Glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM1840 gapA; Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM0341 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (Phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) (dPGM)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" }, { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"CLOAM1538 putative MFS transporter family protein\tK06902 UMF1; MFS transporter, UMF1 family" } ] }, { "name":"04121 Ubiquitin system" }, { "name":"03051 Proteasome [BR:caci03051]", "children":[ { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" } ] }, { "name":"03032 DNA replication proteins [BR:caci03032]", "children":[ { "name":"CLOAM0973 hupA; HU, DNA-binding transcriptional regulator, alpha subunit\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"CLOAM1727 DNA-binding protein HU (DNA-binding protein II) (TL29)\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"CLOAM0001 dnaA; chromosomal replication initiation protein\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"CLOAM1089 dnaB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]" }, { "name":"CLOAM1825 dnaG; DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]" }, { "name":"CLOAM1609 Single-stranded DNA-binding protein (modular protein)\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"CLOAM1746 dnaE; DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"CLOAM1536 putative DNA polymerase III, beta chain (dnaN-like)\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"CLOAM1040 putative DNA polymerase III, delta subunit (holA-like)\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"CLOAM0793 putative DNA polymerase III, delta prime subunit (holB-like)\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"CLOAM1210 DNA polymerase III, gamma\/tau subunits (fragment)\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"CLOAM1007 rnhB; ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]" }, { "name":"CLOAM1706 putative Ribonuclease H\tK03471 rnhC; ribonuclease HIII [EC:3.1.26.4]" }, { "name":"CLOAM0968 ligA; DNA ligase, NAD-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" }, { "name":"CLOAM0203 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0204 N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0502 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0503 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM1327 Modification methylase MjaIII (Adenine-specific methyltransferase MjaIII) (M.MjaIII)\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM1331 gyrA; DNA gyrase, A subunit\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"CLOAM1332 gyrB; DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" }, { "name":"CLOAM1733 topA; DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]" } ] }, { "name":"03036 Chromosome and associated proteins [BR:caci03036]", "children":[ { "name":"CLOAM0250 rnc; dsRNA-specific ribonuclease\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"CLOAM0177 ftcd; Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (Formiminotetrahydrofolate cyclodeaminase)]\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" }, { "name":"CLOAM0973 hupA; HU, DNA-binding transcriptional regulator, alpha subunit\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"CLOAM1727 DNA-binding protein HU (DNA-binding protein II) (TL29)\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"CLOAM0001 dnaA; chromosomal replication initiation protein\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"CLOAM0779 ftsA; Cell division and septation protein ftsA, ATPase domain\tK03590 ftsA; cell division protein FtsA" }, { "name":"CLOAM0347 ftsK; DNA translocase ftsK (DNA translocase SpoIIIE)\tK03466 ftsK; DNA segregation ATPase FtsK\/SpoIIIE, S-DNA-T family" }, { "name":"CLOAM0780 Putative cell division protein FtsQ (ftsQ-like)\tK03589 ftsQ; cell division protein FtsQ" }, { "name":"CLOAM0783 ftsW; Essential cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM0778 ftsZ; Cell division protein FtsZ, tubulin-like GTP-binding protein and GTPase\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"CLOAM0535 hypothetical protein\tK09892 zapB; cell division protein ZapB" }, { "name":"CLOAM1516 putative N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" }, { "name":"CLOAM1033 hypothetical protein; putative signal peptide\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"CLOAM0404 putative Cell division initiation protein,DivIVA-like\tK04074 divIVA; cell division initiation protein" }, { "name":"CLOAM1807 mreB; cell wall structural complex MreBCD, actin-like component MreB\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"CLOAM1806 hypothetical protein; putative signal peptide\tK03570 mreC; rod shape-determining protein MreC" }, { "name":"CLOAM1804 hypothetical protein; putative membrane protein\tK03571 mreD; rod shape-determining protein MreD" }, { "name":"CLOAM1802 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM0277 soj protein\tK03496 parA; chromosome partitioning protein" }, { "name":"CLOAM0278 parB-like domain protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"CLOAM1794 gidA; glucose-inhibited division protein A\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme" }, { "name":"CLOAM0276 putative S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division (gidB-like)\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]" }, { "name":"CLOAM1589 Tyrosine recombinase xerD\tK04763 xerD; integrase\/recombinase XerD" }, { "name":"CLOAM1682 site-specific recombinase, phage integrase family\tK04763 xerD; integrase\/recombinase XerD" }, { "name":"CLOAM1275 Fic family protein\tK04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]" }, { "name":"CLOAM1650 Filamentation induced by cAMP protein Fic\tK04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]" }, { "name":"CLOAM1793 putative GTP-binding protein engB\tK03978 engB; GTP-binding protein" } ] }, { "name":"03400 DNA repair and recombination proteins [BR:caci03400]", "children":[ { "name":"CLOAM1461 Methylated-DNA--protein-cysteine methyltransferase (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase)\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]" }, { "name":"CLOAM0039 putative endonuclease III (nth-like)\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"CLOAM0327 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"CLOAM0287 ung; Uracil-DNA glycosylase\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"CLOAM1877 putative formamidopyrimidine\/5-formyluracil\/5-hydroxymethyluracil DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"CLOAM1175 xthA; Exonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"CLOAM0321 putative ssDNA exonuclease, 5'--> 3'-specific\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM1265 hypothetical protein\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"CLOAM0968 ligA; DNA ligase, NAD-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" }, { "name":"CLOAM0971 uvrA; ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"CLOAM0820 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component\tK03702 uvrB; excinuclease ABC subunit B" }, { "name":"CLOAM0765 hypothetical protein\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"CLOAM0791 Excinuclease ABC, C subunit\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"CLOAM0486 conserved hypothetical protein\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"CLOAM0549 uvrD; Superfamily I DNA and RNA helicases\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"CLOAM0456 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"CLOAM0455 rpoC; RNA polymerase, beta' subunit; binds Zn(II)\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"CLOAM1113 rpoA; DNA-directed RNA polymerase alpha chain (RNAP alpha subunit) (Transcriptase alpha chain) (RNA polymerase alpha subunit)\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"CLOAM0548 putative transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"CLOAM0950 DNA mismatch repair protein\tK03555 mutS; DNA mismatch repair protein MutS" }, { "name":"CLOAM0391 hypothetical protein\tK07456 mutS2; DNA mismatch repair protein MutS2" }, { "name":"CLOAM1824 putative recombination and DNA strand exchange inhibitor protein\tK07456 mutS2; DNA mismatch repair protein MutS2" }, { "name":"CLOAM1302 mutL; DNA mismatch repair protein MutL\tK03572 mutL; DNA mismatch repair protein MutL" }, { "name":"CLOAM0245 xseA; Exonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]" }, { "name":"CLOAM0325 xseB; Exonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]" }, { "name":"CLOAM1746 dnaE; DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"CLOAM1536 putative DNA polymerase III, beta chain (dnaN-like)\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"CLOAM1040 putative DNA polymerase III, delta subunit (holA-like)\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"CLOAM0793 putative DNA polymerase III, delta prime subunit (holB-like)\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"CLOAM1210 DNA polymerase III, gamma\/tau subunits (fragment)\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"CLOAM1609 Single-stranded DNA-binding protein (modular protein)\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"CLOAM0203 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0204 N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0502 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0503 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM1327 Modification methylase MjaIII (Adenine-specific methyltransferase MjaIII) (M.MjaIII)\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM1869 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA" }, { "name":"CLOAM0929 ruvA; Holliday junction DNA helicase RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA" }, { "name":"CLOAM1679 ruvB; Holliday junction helicase, subunit B\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]" }, { "name":"CLOAM0930 ruvC; crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]" }, { "name":"CLOAM0274 Primosomal protein n\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"CLOAM0710 radA; DNA repair protein radA homolog (DNA repair protein sms homolog); putative ATP-dependent protease, with nucleoside triP hydrolase and multiheme cytochrome domains\tK04485 radA; DNA repair protein RadA\/Sms" }, { "name":"CLOAM1537 putative putative DNA repair and genetic recombination (recF-like)\tK03629 recF; DNA replication and repair protein RecF" }, { "name":"CLOAM1698 recG; ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"CLOAM1059 hypothetical protein\tK03584 recO; DNA repair protein RecO (recombination protein O)" }, { "name":"CLOAM0450 recR; recombination protein RecR\tK06187 recR; recombination protein RecR" }, { "name":"CLOAM0036 recN; DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)" }, { "name":"CLOAM0855 conserved hypothetical protein\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"CLOAM1290 conserved hypothetical protein\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"CLOAM1331 gyrA; DNA gyrase, A subunit\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"CLOAM1332 gyrB; DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" }, { "name":"CLOAM1733 topA; DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]" }, { "name":"CLOAM0973 hupA; HU, DNA-binding transcriptional regulator, alpha subunit\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"CLOAM1727 DNA-binding protein HU (DNA-binding protein II) (TL29)\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"CLOAM0980 dinP; Nucleotidyltransferase\/DNA polymerase involved in DNA repair\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]" }, { "name":"CLOAM0776 Protein umuC\tK03502 umuC; DNA polymerase V" }, { "name":"CLOAM0975 Protein umuD [Contains: Protein umuD']\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]" }, { "name":"CLOAM1868 hypothetical protein\tK03565 recX; regulatory protein" }, { "name":"CLOAM1545 putative DNA polymerase III, epsilon subunit:DnaQ exonuclease (dnaQ-like) (DinG-like helicase)\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]" }, { "name":"CLOAM0913 putative B12-dependent ribonucleoside-diphosphate\/-triphosphate reductase (nrdJ-like)\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"CLOAM0268 hypothetical protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]" } ] }, { "name":"03029 Mitochondrial biogenesis [BR:caci03029]", "children":[ { "name":"CLOAM0266 infB; translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2" }, { "name":"CLOAM0529 infC; protein chain initiation factor IF-3\tK02520 infC; translation initiation factor IF-3" }, { "name":"CLOAM1889 tsf; elongation factor Ts\tK02357 tsf; elongation factor Ts" }, { "name":"CLOAM0464 tufB; protein chain elongation factor EF-Tu (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"CLOAM0932 fusA; translation elongation factor EF-G\tK02355 fusA; elongation factor G" }, { "name":"CLOAM1619 fusA-; translation elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"CLOAM1148 era; GTP-binding protein Era\tK03595 era; GTPase" }, { "name":"CLOAM0627 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"CLOAM1110 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"CLOAM1540 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"CLOAM0359 Arginyl-tRNA synthetase 1 (Arginine--tRNA ligase 1) (ArgRS 1)\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"CLOAM1609 Single-stranded DNA-binding protein (modular protein)\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"CLOAM1493 hypothetical protein; putative signal peptide\tK07277 SAM50; outer membrane protein insertion porin family" }, { "name":"CLOAM0757 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"CLOAM0756 grpE; GrpE protein\tK03687 GRPE; molecular chaperone GrpE" }, { "name":"CLOAM1649 groL; Cpn60 chaperonin GroEL, large subunit of GroESL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"CLOAM0817 groES; chaperonin, 10 kDa\tK04078 groES; chaperonin GroES" }, { "name":"CLOAM0758 dnaJ; Chaperone protein DnaJ (Heat shock protein 40) (HSP40)\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"CLOAM1691 iscS; Cysteine desulfurase (ThiI transpersulfidase) (NifS protein homolog)\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"CLOAM0544 Preprotein translocase subunit YidC (modular protein)\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" } ] } ] }, { "name":"09183 Protein families: signaling and cellular processes", "children":[ { "name":"02000 Transporters [BR:caci02000]", "children":[ { "name":"CLOAM0412 ABC transporter, ATP-binding protein, MsbA family (modular protein)\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"CLOAM1019 putative ABC transporter, transmembrane region:ABC transporter related\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"CLOAM1522 mdlB; ABC-type multidrug\/protein\/lipid transport system, ATPase component\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"CLOAM1020 putative ABC transporter (membrane (N-terminal),atp_bind (C-terminal))\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"CLOAM1521 ABC transporter, transmembrane region:ABC transporter related\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"CLOAM1433 putative fused transporter subunits of ABC superfamily: ATP-binding components\tK15738 uup; ABC transport system ATP-binding\/permease protein" }, { "name":"CLOAM1091 hypothetical protein\tK02064 thiB; thiamine transport system substrate-binding protein" }, { "name":"CLOAM1539 potD; spermidine\/putrescine-binding periplasmic protein precursor (SPBP)\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein" }, { "name":"CLOAM0766 potC; Spermidine\/putrescine transport system permease protein potC (ABC transporter)\tK11070 potC; spermidine\/putrescine transport system permease protein" }, { "name":"CLOAM0767 potB; Spermidine\/putrescine transport system permease protein potB (ABC transporter)\tK11071 potB; spermidine\/putrescine transport system permease protein" }, { "name":"CLOAM0768 potA; Spermidine\/putrescine import ATP-binding protein potA (ABC transporter)\tK11072 potA; spermidine\/putrescine transport system ATP-binding protein [EC:7.6.2.11]" }, { "name":"CLOAM0807 putative ABC transporter substrate-binding protein\tK02051 ABC.SN.S; NitT\/TauT family transport system substrate-binding protein" }, { "name":"CLOAM1845 ycjV; putative sugar transporter subunit: ATP-binding component of ABC superfamily transporter\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]" }, { "name":"CLOAM0354 ybbM; putative UPF0014 membrane protein ybbM\tK02069 STAR2; UDP-glucose\/iron transport system permease protein" }, { "name":"CLOAM0353 ybbL; Putative ABC transporter ATP-binding protein\tK02068 STAR1; UDP-glucose\/iron transport system ATP-binding protein" }, { "name":"CLOAM0133 hypothetical protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"CLOAM0169 hypothetical protein; putative signal peptide\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"CLOAM1097 hypothetical protein; putative signal peptide\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"CLOAM1090 conserved hypothetical protein; putative membrane protein\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"CLOAM1095 transporter, putative (modular protein)\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"CLOAM1374 hypothetical protein; putative membrane protein\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"CLOAM1094 ABC transporter, ATP-binding protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"CLOAM1236 ABC transporter, ATP-binding protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"CLOAM1373 hypothetical protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"CLOAM0889 putative Sugar ABC transporter, periplasmic sugar-binding protein\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein" }, { "name":"CLOAM1247 malF; ABC-type sugar transport systems, permease components\tK02025 ABC.MS.P; multiple sugar transport system permease protein" }, { "name":"CLOAM1248 Sugar permeases (modular protein)\tK02026 ABC.MS.P1; multiple sugar transport system permease protein" }, { "name":"CLOAM1518 Phosphonates-binding protein\tK02044 phnD; phosphonate transport system substrate-binding protein" }, { "name":"CLOAM1644 ABC-type phosphonates transport system permease protein precursor\tK02042 phnE; phosphonate transport system permease protein" }, { "name":"CLOAM1519 phnC; phosphonate\/organophosphate ester transporter subunit; ATP-binding component of ABC superfamily\tK02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]" }, { "name":"CLOAM1632 putative ABC-type amino acid transport system,periplasmic component\tK02030 ABC.PA.S; polar amino acid transport system substrate-binding protein" }, { "name":"CLOAM0599 Putative vitamin B12 transport system permease protein (ABC transporter) (btuC-like)\tK02015 ABC.FEV.P; iron complex transport system permease protein" }, { "name":"CLOAM0064 ABC transporter related (fragment)\tK02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]" }, { "name":"CLOAM0598 Putative vitamin B12-binding periplasmic protein precursor (ABC transporter) (btuF-like)\tK25034 btuF; cobalamin transport system substrate-binding protein" }, { "name":"CLOAM0130 znuA; ABC-type Mn\/Zn transport system, periplasmic Mn\/Zn-binding (lipo)protein (surface adhesin A)\tK09815 znuA; zinc transport system substrate-binding protein" }, { "name":"CLOAM0128 ABC transporter, permease protein\tK09816 znuB; zinc transport system permease protein" }, { "name":"CLOAM0129 ABC transporter, ATP-binding protein\tK09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]" }, { "name":"CLOAM1354 Putative cobalt transport system permease protein (ABC transporter) (cbiQ-like)\tK16785 ecfT; energy-coupling factor transport system permease protein" }, { "name":"CLOAM1355 Putative cobalt import ATP-binding protein (ABC transporter) (cbiO-like)\tK01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]" }, { "name":"CLOAM0967 putative Permease YjgP\/YjgQ\tK07091 lptF; lipopolysaccharide export system permease protein" }, { "name":"CLOAM0966 putative Permease\tK11720 lptG; lipopolysaccharide export system permease protein" }, { "name":"CLOAM1759 lptB; putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]" }, { "name":"CLOAM0956 hypothetical protein; putative membrane protein\tK09696 natB; sodium transport system permease protein" }, { "name":"CLOAM0955 ccmA; ABC-type multidrug transport system, ATPase component\tK09697 natA; sodium transport system ATP-binding protein [EC:7.2.2.4]" }, { "name":"CLOAM0622 nosY; ABC-type transport system involved in multi-copper enzyme maturation, permease component\tK25151 gldF; gliding motility-associated transport system permease protein" }, { "name":"CLOAM0621 ccmA1; ABC-type multidrug transport system, ATPase component\tK25152 gldA; gliding motility-associated transport system ATP-binding protein" }, { "name":"CLOAM0623 hypothetical protein; putative signal peptide\tK25153 gldG; gliding motility-associatede transport system auxiliary component" }, { "name":"CLOAM0143 hypothetical protein; putative membrane protein\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"CLOAM1268 hypothetical protein; putative membrane protein\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"CLOAM1269 ABC transporter, ATP-binding protein\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]" }, { "name":"CLOAM0084 ABC-type transport systems, involved in lipoprotein release, permease components\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"CLOAM1734 putative ABC-type transport systems, involved in lipoprotein release, permease components\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"CLOAM1897 putative ABC-type transport systems, involved in lipoprotein release, permease components\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"CLOAM0085 ABC transporter, ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"CLOAM1896 ABC transporter, ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"CLOAM1146 putative Na+ driven multidrug efflux pump\tK26937 dinF; MATE family, multidrug efflux pump" }, { "name":"CLOAM1538 putative MFS transporter family protein\tK06902 UMF1; MFS transporter, UMF1 family" }, { "name":"CLOAM1752 putative PEP-protein phosphotransferase of PTS system (enzyme I)\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]" }, { "name":"CLOAM1753 ptsH; phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr" }, { "name":"CLOAM0343 hypothetical protein\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]" }, { "name":"CLOAM1449 hypothetical protein; putative membrane protein\tK10716 kch; voltage-gated potassium channel" }, { "name":"CLOAM1406 hypothetical protein; putative membrane protein\tK07114 yfbK; Ca-activated chloride channel homolog" }, { "name":"CLOAM1407 BatA protein (fragment)\tK07114 yfbK; Ca-activated chloride channel homolog" }, { "name":"CLOAM0608 MotA\/TolQ\/ExbB proton channel family protein (modular protein)\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"CLOAM0991 MotA\/TolQ\/ExbB proton channel family protein (fragment)\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"CLOAM1739 hypothetical protein; putative membrane protein\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"CLOAM0990 hypothetical protein\tK03559 exbD; biopolymer transport protein ExbD" }, { "name":"CLOAM1791 Transporter\tK03284 corA; magnesium transporter" }, { "name":"CLOAM0176 putative CBS domain protein\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" }, { "name":"CLOAM1233 CBS domain protein (modular protein)\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" }, { "name":"CLOAM0065 hypothetical protein; putative signal peptide\tK16092 btuB; vitamin B12 transporter" }, { "name":"CLOAM0087 hypothetical protein; putative signal peptide\tK12340 tolC; outer membrane protein" }, { "name":"CLOAM1493 hypothetical protein; putative signal peptide\tK07277 SAM50; outer membrane protein insertion porin family" }, { "name":"CLOAM0052 hypothetical protein; putative signal peptide\tK05807 bamD; outer membrane protein assembly factor BamD" }, { "name":"CLOAM1032 outer membrane efflux protein (fragment)\tK18138 acrB; multidrug efflux pump" }, { "name":"CLOAM1457 Trk-type K+ transport systems, membrane components (modular protein)\tK03498 trkH; trk\/ktr system potassium uptake protein" }, { "name":"CLOAM1456 trkA; K+ transport systems, NAD-binding component\tK03499 trkA; trk\/ktr system potassium uptake protein" }, { "name":"CLOAM0379 Chromate transporter\tK07240 chrA; chromate transporter" }, { "name":"CLOAM0380 Chromate transport protein\tK07240 chrA; chromate transporter" }, { "name":"CLOAM0742 putative Na\/Pi cotransporter II-related\tK03324 yjbB; phosphate:Na+ symporter" }, { "name":"CLOAM1158 conserved hypothetical protein; putative membrane protein\tK03325 ACR3; arsenite transporter" }, { "name":"CLOAM0792 conserved hypothetical protein; putative membrane protein\tK03980 murJ; putative peptidoglycan lipid II flippase" }, { "name":"CLOAM0135 putative Auxin Efflux Carrier\tK24180 mleP; malate permease and related proteins" }, { "name":"CLOAM0783 ftsW; Essential cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"CLOAM1022 hppA; Pyrophosphate-energized proton pump (Pyrophosphate-energized inorganic pyrophosphatase) (H+-PPase) (Membrane-bound proton-translocating pyrophosphatase)\tK15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]" }, { "name":"CLOAM1513 putative Na+-transporting methylmalonyl-CoA\/oxaloacetate decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM1771 putative S-Methylmalonyl-CoA decarboxylase,sodium-translocating subunit, beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"CLOAM1715 putative S-methylmalonyl-CoA carboxyltransferase (Transcarboxylase) 12S subunit\tK01604 mmdA; methylmalonyl-CoA decarboxylase subunit alpha [EC:7.2.4.3]" }, { "name":"CLOAM1768 putative S-Methylmalonyl-CoA decarboxylase, alpha chain\tK01604 mmdA; methylmalonyl-CoA decarboxylase subunit alpha [EC:7.2.4.3]" }, { "name":"CLOAM1033 hypothetical protein; putative signal peptide\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"CLOAM0434 putative Non-specific protein-tyrosine kinase\tK16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]" }, { "name":"CLOAM1905 feoB; Ferrous ion uptake system protein FeoB (predicted GTPase)\tK04759 feoB; ferrous iron transport protein B" } ] }, { "name":"02044 Secretion system [BR:caci02044]", "children":[ { "name":"CLOAM0087 hypothetical protein; putative signal peptide\tK12340 tolC; outer membrane protein" }, { "name":"CLOAM0731 putative bifunctional prepilin leader peptidase and methylase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"CLOAM1401 putative Pilus biogenesis protein tapA precursor\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"CLOAM1390 type IV pilus biogenesis protein PilB\tK02652 pilB; type IV pilus assembly protein PilB" }, { "name":"CLOAM1389 type IV pilus biogenesis protein PilC\tK02653 pilC; type IV pilus assembly protein PilC" }, { "name":"CLOAM1396 putative type IV pilus biogenesis protein PilM\tK02662 pilM; type IV pilus assembly protein PilM" }, { "name":"CLOAM1400 pilT-; twitching motility protein PilT\tK02669 pilT; twitching motility protein PilT" }, { "name":"CLOAM0403 YGGT family protein (fragment)\tK02221 yggT; YggT family protein" }, { "name":"CLOAM1358 cytidine\/deoxycytidylate deaminase family protein\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]" }, { "name":"CLOAM0390 hypothetical protein; putative membrane protein\tK02238 comEC; competence protein ComEC" }, { "name":"CLOAM1732 secA; preprotein translocase secA subunit, essential ATPase protein\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"CLOAM1010 secD; protein-export membrane protein secD, accessory membrane protein\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"CLOAM0462 secE; Preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"CLOAM1009 secF; protein-export membrane protein secF, accessory membrane protein\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"CLOAM1170 secG; protein-export membrane protein secG, essential membrane protein\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"CLOAM1120 secY; preprotein translocase secY subunit, essential membrane protein\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"CLOAM1602 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"CLOAM0799 ftsY; Cell division protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"CLOAM0006 yajC; Preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"CLOAM0544 Preprotein translocase subunit YidC (modular protein)\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" } ] }, { "name":"02042 Bacterial toxins [BR:caci02042]", "children":[ { "name":"CLOAM0176 putative CBS domain protein\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" }, { "name":"CLOAM1233 CBS domain protein (modular protein)\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" } ] }, { "name":"02022 Two-component system [BR:caci02022]", "children":[ { "name":"CLOAM0876 putative sigma-54 dependent DNA-binding response regulator\tK13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX" } ] }, { "name":"02035 Bacterial motility proteins [BR:caci02035]", "children":[ { "name":"CLOAM1400 pilT-; twitching motility protein PilT\tK02669 pilT; twitching motility protein PilT" }, { "name":"CLOAM1401 putative Pilus biogenesis protein tapA precursor\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"CLOAM1390 type IV pilus biogenesis protein PilB\tK02652 pilB; type IV pilus assembly protein PilB" }, { "name":"CLOAM1389 type IV pilus biogenesis protein PilC\tK02653 pilC; type IV pilus assembly protein PilC" }, { "name":"CLOAM0731 putative bifunctional prepilin leader peptidase and methylase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"CLOAM1396 putative type IV pilus biogenesis protein PilM\tK02662 pilM; type IV pilus assembly protein PilM" } ] }, { "name":"03037 Cilium and associated proteins" }, { "name":"04812 Cytoskeleton proteins [BR:caci04812]", "children":[ { "name":"CLOAM0773 conserved hypothetical protein\tK06990 MEMO1; MEMO1 family protein" }, { "name":"CLOAM1807 mreB; cell wall structural complex MreBCD, actin-like component MreB\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"CLOAM0778 ftsZ; Cell division protein FtsZ, tubulin-like GTP-binding protein and GTPase\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"CLOAM0779 ftsA; Cell division and septation protein ftsA, ATPase domain\tK03590 ftsA; cell division protein FtsA" }, { "name":"CLOAM0277 soj protein\tK03496 parA; chromosome partitioning protein" }, { "name":"CLOAM0278 parB-like domain protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" } ] }, { "name":"04147 Exosome [BR:caci04147]", "children":[ { "name":"CLOAM1689 Chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"CLOAM1651 eno; enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"CLOAM1530 Glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM1840 gapA; Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"CLOAM0802 pgk; 3-phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"CLOAM1564 ahpC; Peroxiredoxin\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]" }, { "name":"CLOAM1649 groL; Cpn60 chaperonin GroEL, large subunit of GroESL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"CLOAM0757 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"CLOAM1751 pgi; Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"CLOAM1588 guaB; Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) (Superoxide-inducible protein 12) (SOI12)\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]" }, { "name":"CLOAM0464 tufB; protein chain elongation factor EF-Tu (duplicate of tufA)\tK02358 tuf; elongation factor Tu" }, { "name":"CLOAM0810 putative acetyl-CoA acetyltransferase with thiolase domain (YqeF)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"CLOAM1471 ahcY; S-adenosyl-L-homocysteine hydrolase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"CLOAM1458 adk; Adenylate kinase (ATP-AMP transphosphorylase)\tK00939 adk; adenylate kinase [EC:2.7.4.3]" }, { "name":"CLOAM0177 ftcd; Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (Formiminotetrahydrofolate cyclodeaminase)]\tK13990 FTCD; glutamate formiminotransferase \/ formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]" }, { "name":"CLOAM0630 glnA; glutamine synthetase (glutamate--ammonia ligase)\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"CLOAM1772 serA; D-3-phosphoglycerate dehydrogenase (PGDH)\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"CLOAM1899 purH; Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"CLOAM1756 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"CLOAM1668 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"CLOAM0341 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (Phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) (dPGM)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]" } ] }, { "name":"02048 Prokaryotic defense system [BR:caci02048]", "children":[ { "name":"CLOAM0855 conserved hypothetical protein\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"CLOAM1290 conserved hypothetical protein\tK15342 cas1; CRISP-associated protein Cas1" }, { "name":"CLOAM0856 conserved hypothetical protein\tK09951 cas2; CRISPR-associated protein Cas2" }, { "name":"CLOAM1289 conserved hypothetical protein\tK09951 cas2; CRISPR-associated protein Cas2" }, { "name":"CLOAM1291 putative CRISPR-associated helicase Cas3, core\tK07012 cas3; CRISPR-associated endonuclease\/helicase Cas3 [EC:3.1.-.- 5.6.2.4]" }, { "name":"CLOAM1288 conserved hypothetical protein\tK07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]" }, { "name":"CLOAM1294 hypothetical protein\tK19114 csh1; CRISPR-associated protein Csh1" }, { "name":"CLOAM1293 conserved hypothetical protein\tK19115 csh2; CRISPR-associated protein Csh2" }, { "name":"CLOAM1292 conserved hypothetical protein\tK19116 cas5h; CRISPR-associated protein Cas5h" }, { "name":"CLOAM0841 hypothetical protein\tK07016 csm1; CRISPR-associated protein Csm1" }, { "name":"CLOAM0843 conserved hypothetical protein\tK09002 csm3; CRISPR-associated protein Csm3" }, { "name":"CLOAM0844 hypothetical protein\tK19139 csm4; CRISPR-associated protein Csm4" }, { "name":"CLOAM0845 hypothetical protein\tK19140 csm5; CRISPR-associated protein Csm5" }, { "name":"CLOAM0220 DEAD\/DEAH box helicase\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]" }, { "name":"CLOAM0489 conserved hypothetical protein\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]" }, { "name":"CLOAM0219 putative Type I restriction-modification system specificity subunit\tK01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]" }, { "name":"CLOAM0217 Type I restriction-modification system methyltransferase subunit\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]" }, { "name":"CLOAM0488 Restriction modification system DNA specificity domain:N-6 DNA methylase:Type I restriction-modification system, M subunit\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]" }, { "name":"CLOAM0203 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0204 N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0502 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0503 putative N6 adenine-specific DNA methyltransferase, D12 class\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM1327 Modification methylase MjaIII (Adenine-specific methyltransferase MjaIII) (M.MjaIII)\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]" }, { "name":"CLOAM0337 putative Modification methylase TaqI (Adenine-specific methyltransferase TaqI) (M.TaqI)\tK07317 K07317; adenine-specific DNA-methyltransferase [EC:2.1.1.72]" }, { "name":"CLOAM1838 BstYI methyltransferase\tK07319 yhdJ; adenine-specific DNA-methyltransferase [EC:2.1.1.72]" }, { "name":"CLOAM0155 Modification methylase (fragment)\tK00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]" }, { "name":"CLOAM0148 DNA methylase N-4\/N-6\tK24451 zim; modification methylase" }, { "name":"CLOAM0150 putative Modification methylase MjaI (N-4 cytosine-specific methyltransferase MjaI) (M.MjaI)\tK24451 zim; modification methylase" }, { "name":"CLOAM1257 Type II restriction modification system,methylation subunit\tK24451 zim; modification methylase" }, { "name":"CLOAM1864 conserved hypothetical protein\tK19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-]" }, { "name":"CLOAM0778 ftsZ; Cell division protein FtsZ, tubulin-like GTP-binding protein and GTPase\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"CLOAM1807 mreB; cell wall structural complex MreBCD, actin-like component MreB\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"CLOAM1691 iscS; Cysteine desulfurase (ThiI transpersulfidase) (NifS protein homolog)\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" } ] }, { "name":"04030 G protein-coupled receptors" }, { "name":"04050 Cytokine receptors" }, { "name":"04054 Pattern recognition receptors" }, { "name":"03310 Nuclear receptors" }, { "name":"04040 Ion channels" }, { "name":"04031 GTP-binding proteins" }, { "name":"04052 Cytokines and neuropeptides" }, { "name":"04515 Cell adhesion molecules" }, { "name":"04090 CD molecules" }, { "name":"01504 Antimicrobial resistance genes [BR:caci01504]", "children":[ { "name":"CLOAM1033 hypothetical protein; putative signal peptide\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"CLOAM1032 outer membrane efflux protein (fragment)\tK18138 acrB; multidrug efflux pump" }, { "name":"CLOAM0087 hypothetical protein; putative signal peptide\tK12340 tolC; outer membrane protein" } ] }, { "name":"00535 Proteoglycans" }, { "name":"00536 Glycosaminoglycan binding proteins" }, { "name":"00537 Glycosylphosphatidylinositol (GPI)-anchored proteins" }, { "name":"04091 Lectins" }, { "name":"04990 Domain-containing proteins not elsewhere classified" } ] }, { "name":"09185 Viral protein families", "children":[ { "name":"03200 Viral proteins" }, { "name":"03210 Viral fusion proteins" } ] }, { "name":"09184 RNA family", "children":[ { "name":"03100 Non-coding RNAs [BR:caci03100]", "children":[ { "name":"CLOAMtRNA28 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"CLOAMtRNA29 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"CLOAMtRNA46 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"CLOAMtRNA23 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA26 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA6 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA8 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"CLOAMtRNA16 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn" }, { "name":"CLOAMtRNA10 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp" }, { "name":"CLOAMtRNA35 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys" }, { "name":"CLOAMtRNA3 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"CLOAMtRNA4 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"CLOAMtRNA44 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"CLOAMtRNA45 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"CLOAMtRNA32 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA34 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA37 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA40 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"CLOAMtRNA27 tRNA-His\tK14226 tRNA-His; tRNA His" }, { "name":"CLOAMtRNA22 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"CLOAMtRNA11 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA12 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA13 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA33 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA36 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"CLOAMtRNA21 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"CLOAMtRNA43 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"CLOAMtRNA20 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA24 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA25 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"CLOAMtRNA5 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe" }, { "name":"CLOAMtRNA14 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"CLOAMtRNA30 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"CLOAMtRNA7 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"CLOAMtRNA1 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA17 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA2 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA31 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"CLOAMtRNA38 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"CLOAMtRNA41 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"CLOAMtRNA9 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"CLOAMtRNA42 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp" }, { "name":"CLOAMtRNA39 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr" }, { "name":"CLOAMtRNA15 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"CLOAMtRNA18 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"CLOAMtRNA19 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"CLOAM_23s_1 ribosomal RNA 23s\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"CLOAM_23s_2 ribosomal RNA 23s\tK01980 23SrRNA; 23S ribosomal RNA" }, { "name":"CLOAM_5s_1 ribosomal RNA 5s\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"CLOAM_5s_2 ribosomal RNA 5s\tK01985 5SrRNA; 5S ribosomal RNA" } ] } ] } ] }, { "name":"09190 Not Included in Pathway or Brite", "children":[ { "name":"09191 Unclassified: metabolism", "children":[ { "name":"99980 Enzymes with EC numbers", "children":[ { "name":"CLOAM1731 putative NADH-dependent butanol dehydrogenase\tK19955 adh2; alcohol dehydrogenase [EC:1.1.1.-]" }, { "name":"CLOAM0722 putative dehydrogenase, 2Fe-2S ferredoxin-like subunit, small chain\tK03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3]" }, { "name":"CLOAM1596 putative dehydrogenase, 2Fe-2S ferredoxin-like subunit, small chain\tK03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3]" }, { "name":"CLOAM1597 putative dehydrogenase, FAD binding subunit,medium chain\tK03519 coxM; aerobic carbon-monoxide dehydrogenase medium subunit [EC:1.2.5.3]" }, { "name":"CLOAM1038 iorA; indolepyruvate ferredoxin oxidoreductase, alpha chain\tK00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]" }, { "name":"CLOAM1037 iorB; indolepyruvate ferredoxin oxidoreductase, beta chain\tK00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8]" }, { "name":"CLOAM1184 putative ferredoxin, 2Fe-2S (thioredoxin-like [2Fe-2S] ferredoxin) (hymB-like partial match)\tK17992 hndB; NADP-reducing hydrogenase subunit HndB [EC:1.12.1.3]" }, { "name":"CLOAM1181 putative [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit beta (hymB-like)\tK18331 hndC; NADP-reducing hydrogenase subunit HndC [EC:1.12.1.3]" }, { "name":"CLOAM1183 hymB; [Fe] hydrogenase (Fe-only hydrogenase) (ferredoxin bidirectional hydrogenase), subunit beta; putative signal peptide\tK18331 hndC; NADP-reducing hydrogenase subunit HndC [EC:1.12.1.3]" }, { "name":"CLOAM1366 dfx; rubredoxin-dependent superoxide reductase (SOR) (desulfoferrodoxin)\tK05919 dfx; superoxide reductase [EC:1.15.1.2]" }, { "name":"CLOAM0902 putative enzyme with radical SAM domain\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]" }, { "name":"CLOAM1254 putative anaerobic ribonucleotide reductase activating enzyme (NrdG)\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]" }, { "name":"CLOAM1515 putative enzyme with radical SAM domain protein (Fe-S protein)\tK04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4]" }, { "name":"CLOAM1167 pcm; L-isoaspartate protein carboxylmethyltransferase type II\tK00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]" }, { "name":"CLOAM0318 putative Apolipoprotein N-acyltransferase precursor\tK03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]" }, { "name":"CLOAM0019 putative acyltransferase\tK22617 olsA; lyso-ornithine lipid O-acyltransferase [EC:2.3.1.270]" }, { "name":"CLOAM0212 hypothetical protein\tK21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29]" }, { "name":"CLOAM0105 lgt; prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]" }, { "name":"CLOAM0809 putative Glutamate-1-semialdehyde 2,1-aminomutase (GSA) (Glutamate-1-semialdehyde aminotransferase) (GSA-AT)\tK21585 kat; 3-aminobutanoyl-CoA transaminase [EC:2.6.1.111]" }, { "name":"CLOAM0915 putative ApbE-like lipoprotein precursor\tK03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]" }, { "name":"CLOAM1200 RNA-directed DNA polymerase (Reverse transcriptase)\tK00986 ltrA; RNA-directed DNA polymerase [EC:2.7.7.49]" }, { "name":"CLOAM0987 conserved hypothetical protein\tK18672 dacA; diadenylate cyclase [EC:2.7.7.85]" }, { "name":"CLOAM1754 hprK; HPr kinase\/phosphorylase\tK06023 hprK; HPr kinase\/phosphorylase [EC:2.7.11.- 2.7.4.-]" }, { "name":"CLOAM1594 putative Formyl-CoA transferase\tK18702 uctC; CoA:oxalate CoA-transferase [EC:2.8.3.19]" }, { "name":"CLOAM1829 ymdB; conserved hypothetical protein\tK23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]" }, { "name":"CLOAM0261 conserved hypothetical protein; putative thioesterase domain\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]" }, { "name":"CLOAM1321 putative capsular polysaccharide biosynthesis homolog ywqE\tK01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]" }, { "name":"CLOAM1027 putative PHP domain protein\tK07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97]" }, { "name":"CLOAM1231 hypothetical protein; putative membrane protein\tK07037 pgpH; cyclic-di-AMP phosphodiesterase PgpH [EC:3.1.4.-]" }, { "name":"CLOAM0419 hypothetical protein\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]" }, { "name":"CLOAM1263 tatD; Mg-dependent DNase\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]" }, { "name":"CLOAM0215 Chain A, D20c mutant of T4 lysozyme\tK01185 E3.2.1.17; lysozyme [EC:3.2.1.17]" }, { "name":"CLOAM0490 Chain A, D20c mutant of T4 lysozyme\tK01185 E3.2.1.17; lysozyme [EC:3.2.1.17]" }, { "name":"CLOAM0007 def; polypeptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]" }, { "name":"CLOAM0687 conserved hypothetical protein; putative polysaccharide deacetylase domain\tK22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]" }, { "name":"CLOAM0339 putative endoribonuclease L-PSP\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]" }, { "name":"CLOAM1325 MoxR family protein\tK03924 moxR; MoxR-like ATPase [EC:3.6.3.-]" }, { "name":"CLOAM1410 MoxR family protein\tK03924 moxR; MoxR-like ATPase [EC:3.6.3.-]" }, { "name":"CLOAM1674 putative predicted sugar kinase\tK23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase \/ NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]" }, { "name":"CLOAM0918 hgdC; Activator of (R)-2-hydroxyglutaryl-CoA dehydratase\tK23876 hgdC; (R)-2-hydroxyacyl-CoA dehydratese activating ATPase [EC:5.6.1.9]" }, { "name":"CLOAM0864 Capsule biosynthesis protein CapB\tK01932 capB; gamma-polyglutamate synthase [EC:6.3.2.-]" }, { "name":"CLOAM1527 rnfD; electron transport complex protein rnfD\tK03614 rnfD; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2]" }, { "name":"CLOAM1528 electron transport complex protein rnfC, NAD and 4Fe-4S binding subunit (rnfC fragment)\tK03615 rnfC; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2]" }, { "name":"CLOAM1523 electron transport complex protein rnfB,polyferredoxin subunit (rnfB module)\tK03616 rnfB; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2]" }, { "name":"CLOAM0754 Cation transport ATPase\tK01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]" }, { "name":"CLOAM0745 cadmium-translocating P-type ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]" } ] }, { "name":"99981 Carbohydrate metabolism" }, { "name":"99982 Energy metabolism", "children":[ { "name":"CLOAM1526 RnfG; electron transport complex protein rnfG; FMN-binding domain\tK03612 rnfG; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G" }, { "name":"CLOAM1525 rnfE; electron transport complex protein rnfE\tK03613 rnfE; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E" }, { "name":"CLOAM1524 rnfA; electron transport complex protein rnfA\tK03617 rnfA; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A" } ] }, { "name":"99983 Lipid metabolism" }, { "name":"99984 Nucleotide metabolism" }, { "name":"99985 Amino acid metabolism", "children":[ { "name":"CLOAM0163 predicted enzyme with a TIM-barrel fold\tK06997 yggS; PLP dependent protein" } ] }, { "name":"99986 Glycan metabolism", "children":[ { "name":"CLOAM1324 hypothetical protein; putative membrane protein\tK07027 K07027; glycosyltransferase 2 family protein" } ] }, { "name":"99987 Cofactor metabolism", "children":[ { "name":"CLOAM1488 putative Molybdopterin-guanine dinucleotide biosynthesis protein B\tK03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein" } ] }, { "name":"99988 Secondary metabolism" }, { "name":"99999 Others" } ] }, { "name":"09192 Unclassified: genetic information processing", "children":[ { "name":"99973 Transcription", "children":[ { "name":"CLOAM1335 cold-shock domain family protein\tK03704 cspA; cold shock protein" } ] }, { "name":"99974 Translation" }, { "name":"99975 Protein processing", "children":[ { "name":"CLOAM1084 hypothetical protein\tK03545 tig; trigger factor" }, { "name":"CLOAM1778 smpB; SsrA-binding protein\tK03664 smpB; SsrA-binding protein" }, { "name":"CLOAM1782 Mg chelatase-related protein\tK07391 comM; magnesium chelatase family protein" }, { "name":"CLOAM0713 conserved hypothetical protein\tK07397 yhfA; putative redox protein" }, { "name":"CLOAM1179 putative MPT insertase (molybdopyranopterin monophosphate insertase) (Xanthine dehydrogenase accessory protein) (chaperone XdhC) (XdhC)\tK07402 xdhC; xanthine dehydrogenase accessory factor" } ] }, { "name":"99976 Replication and repair", "children":[ { "name":"CLOAM0117 DNA recombination protein rmuC homolog\tK09760 rmuC; DNA recombination protein RmuC" }, { "name":"CLOAM0487 conserved hypothetical protein\tK07459 ybjD; putative ATP-dependent endonuclease of the OLD family" }, { "name":"CLOAM1743 conserved hypothetical protein\tK07460 yraN; putative endonuclease" }, { "name":"CLOAM0121 DNA processing protein DprA, putative (fragment)\tK04096 smf; DNA processing protein" }, { "name":"CLOAM1378 ATPase, AAA family\tK07478 ycaJ; putative ATPase" }, { "name":"CLOAM0563 hypothetical protein\tK07491 rayT; REP-associated tyrosine transposase" }, { "name":"CLOAM0588 transposase (fragment)\tK07491 rayT; REP-associated tyrosine transposase" }, { "name":"CLOAM0695 transposase (fragment)\tK07491 rayT; REP-associated tyrosine transposase" }, { "name":"CLOAM0145 Integrase, catalytic domain (fragment)\tK07497 K07497; putative transposase" }, { "name":"CLOAM0233 hypothetical protein\tK07497 K07497; putative transposase" }, { "name":"CLOAM0476 hypothetical protein\tK07497 K07497; putative transposase" } ] }, { "name":"99979 Viral proteins" }, { "name":"99998 Others", "children":[ { "name":"CLOAM0449 conserved hypothetical protein\tK09747 ebfC; nucleoid-associated protein EbfC" } ] } ] }, { "name":"09193 Unclassified: signaling and cellular processes", "children":[ { "name":"99977 Transport", "children":[ { "name":"CLOAM0136 putative low-affinity inorganic phosphate transporter (pitA-like)\tK03306 TC.PIT; inorganic phosphate transporter, PiT family" } ] }, { "name":"99978 Cell growth", "children":[ { "name":"CLOAM0543 predicted RNA-binding protein (modular protein)\tK06346 jag; spoIIIJ-associated protein" } ] }, { "name":"99993 Cell motility" }, { "name":"99995 Signaling proteins", "children":[ { "name":"CLOAM0883 phoH family protein\tK07175 phoH2; PhoH-like ATPase" } ] }, { "name":"99992 Structural proteins", "children":[ { "name":"CLOAM1383 hypothetical protein; putative signal peptide\tK06142 hlpA; outer membrane protein" }, { "name":"CLOAM0865 Capsule biosynthesis protein CapC\tK22116 capC; gamma-polyglutamate biosynthesis protein CapC" }, { "name":"CLOAM0086 putative efflux transporter, RND family, MFP subunit\tK02005 ABC.CD.TX; HlyD family secretion protein" }, { "name":"CLOAM0620 hypothetical protein; putative signal peptide\tK02005 ABC.CD.TX; HlyD family secretion protein" }, { "name":"CLOAM1477 conserved hypothetical protein; putative membrane protein\tK11744 tqsA; AI-2 transport protein TqsA" } ] }, { "name":"99994 Others" } ] }, { "name":"09194 Poorly characterized", "children":[ { "name":"99996 General function prediction only", "children":[ { "name":"CLOAM1823 hypothetical protein; putative membrane protein\tK03558 cvpA; membrane protein required for colicin V production" }, { "name":"CLOAM1879 Putative ATP dependant helicase yprA\tK06877 K06877; DEAD\/DEAH box helicase domain-containing protein" }, { "name":"CLOAM0954 putative Patatin\tK07001 K07001; NTE family protein" }, { "name":"CLOAM1013 hypothetical protein; putative signal peptide\tK07001 K07001; NTE family protein" }, { "name":"CLOAM1898 hypothetical protein; putative membrane protein\tK07058 K07058; membrane protein" }, { "name":"CLOAM1213 conserved hypothetical protein; putative LemA family protein\tK03744 lemA; LemA protein" } ] }, { "name":"99997 Function unknown", "children":[ { "name":"CLOAM1452 conserved hypothetical protein\tK06872 K06872; uncharacterized protein" }, { "name":"CLOAM1835 conserved hypothetical protein\tK06921 K06921; uncharacterized protein" }, { "name":"CLOAM0940 putative Abortive infection protein\tK06926 K06926; uncharacterized protein" }, { "name":"CLOAM1466 KH domain protein\tK06960 K06960; uncharacterized protein" }, { "name":"CLOAM0977 putative Membrane protein, precursor\tK07090 K07090; uncharacterized protein" }, { "name":"CLOAM1858 hypothetical protein\tK07164 K07164; uncharacterized protein" }, { "name":"CLOAM0545 conserved hypothetical protein\tK08998 K08998; uncharacterized protein" }, { "name":"CLOAM1810 hypothetical protein; putative signal peptide\tK09005 K09005; uncharacterized protein" }, { "name":"CLOAM1871 conserved hypothetical protein\tK09129 K09129; uncharacterized protein" }, { "name":"CLOAM0772 conserved hypothetical protein\tK09141 K09141; uncharacterized protein" }, { "name":"CLOAM0394 conserved hypothetical protein\tK09163 K09163; uncharacterized protein" }, { "name":"CLOAM0674 conserved hypothetical protein\tK09726 K09726; uncharacterized protein" }, { "name":"CLOAM0009 hypothetical protein; putative membrane protein\tK09729 K09729; uncharacterized protein" }, { "name":"CLOAM0826 hypothetical protein\tK09749 K09749; uncharacterized protein" }, { "name":"CLOAM1637 conserved hypothetical protein\tK09797 K09797; uncharacterized protein" }, { "name":"CLOAM1042 hypothetical protein\tK09798 K09798; uncharacterized protein" }, { "name":"CLOAM1809 conserved hypothetical protein\tK09798 K09798; uncharacterized protein" }, { "name":"CLOAM0186 conserved hypothetical protein\tK01163 K01163; uncharacterized protein" }, { "name":"CLOAM1664 conserved hypothetical protein\tK07502 yprB; uncharacterized protein" }, { "name":"CLOAM0137 conserved hypothetical protein\tK07220 K07220; uncharacterized protein" }, { "name":"CLOAM0264 hypothetical protein\tK07742 ylxR; uncharacterized protein" } ] } ] } ] } ] }