{
	"name":"cber03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"B5D82_05220 DNA cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family",
				"children":[
				{
					"name":"B5D82_03620 hypothetical protein\tK19693 tfoS; AraC family transcriptional regulator, chitin signaling transcriptional activator"
				},
				{
					"name":"B5D82_19385 hypothetical protein\tK13652 K13652; AraC family transcriptional regulator"
				},
				{
					"name":"B5D82_12310 hypothetical protein\tK13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response \/ DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
				},
				{
					"name":"B5D82_00670 GlxA family transcriptional regulator\tK17736 cdhR; AraC family transcriptional regulator, carnitine catabolism transcriptional activator"
				}
				]
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"B5D82_12070 LysR family transcriptional regulator\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"B5D82_16130 transcriptional regulator GcvA\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"B5D82_08740 transcriptional regulator IlvY\tK02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC"
				},
				{
					"name":"B5D82_13405 LysR family transcriptional regulator\tK03576 metR; LysR family transcriptional regulator, regulator for metE and metH"
				},
				{
					"name":"B5D82_01195 hypothetical protein\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"B5D82_07630 DNA-binding transcriptional regulator OxyR\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"B5D82_06050 LysR family transcriptional regulator ArgP\tK05596 argP; LysR family transcriptional regulator, arginine and lysine transport system\/DNA replication regulator"
				},
				{
					"name":"B5D82_13795 transcriptional regulator CysB\tK13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"B5D82_13850 LysR family transcriptional regulator\tK21699 bauR; LysR family transcriptional regulator, transcriptional activator for bauABCD operon"
				},
				{
					"name":"B5D82_13890 LysR family transcriptional regulator\tK21699 bauR; LysR family transcriptional regulator, transcriptional activator for bauABCD operon"
				},
				{
					"name":"B5D82_19010 LysR family transcriptional regulator\tK23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator"
				}
				]
			},
			{
				"name":"DeoR family"
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"B5D82_14425 DNA-binding transcriptional regulator GalS\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"B5D82_10270 hutC; histidine utilization repressor\tK05836 hutC; GntR family transcriptional regulator, histidine utilization repressor"
				},
				{
					"name":"B5D82_15150 fadR; fatty acid metabolism transcriptional regulator FadR\tK03603 fadR; GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA"
				},
				{
					"name":"B5D82_00510 transcriptional regulator PdhR\tK05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex"
				},
				{
					"name":"B5D82_13245 FadR family transcriptional regulator\tK19775 exuR; GntR family transcriptional regulator, hexuronate regulon transcriptional repressor"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"B5D82_04225 transcriptional regulator BetI\tK02167 betI; TetR\/AcrR family transcriptional regulator, transcriptional repressor of bet genes"
				},
				{
					"name":"B5D82_07425 nucleoid occlusion factor SlmA\tK05501 slmA; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"B5D82_18270 TetR\/AcrR family transcriptional regulator\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"B5D82_18820 TetR\/AcrR family transcriptional regulator\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"B5D82_18920 TetR\/AcrR family transcriptional regulator\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"B5D82_04345 TetR family transcriptional regulator\tK16137 nemR; TetR\/AcrR family transcriptional regulator, transcriptional repressor for nem operon"
				},
				{
					"name":"B5D82_10645 DNA-binding transcriptional regulator FabR\tK22105 fabR; TetR\/AcrR family transcriptional regulator, fatty acid biosynthesis regulator"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"B5D82_00235 leucine-responsive transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"B5D82_12860 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"B5D82_18100 leucine-responsive transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"B5D82_02580 Lrp\/AsnC family transcriptional regulator\tK05800 decR; Lrp\/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator"
				}
				]
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"B5D82_14930 MarR family transcriptional regulator\tK06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"B5D82_03355 MerR family transcriptional regulator\tK08365 merR; MerR family transcriptional regulator, mercuric resistance operon regulatory protein"
				},
				{
					"name":"B5D82_10530 MerR family transcriptional regulator\tK08365 merR; MerR family transcriptional regulator, mercuric resistance operon regulatory protein"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"B5D82_13535 ferric iron uptake transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				}
				]
			},
			{
				"name":"IclR family"
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"B5D82_04285 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"B5D82_05005 transcriptional regulator FNR\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				}
				]
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"B5D82_02425 iscR; Fe-S cluster assembly transcriptional regulator IscR\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor"
				}
				]
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"B5D82_14450 transcriptional regulator\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"B5D82_06720 ArsR family transcriptional regulator\tK22042 hlyU; ArsR family transcriptional regulator, virulence genes transcriptional regulator"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"B5D82_17010 MurR\/RpiR family transcriptional regulator\tK19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator"
				},
				{
					"name":"B5D82_09750 transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"B5D82_09170 biotin--[acetyl-CoA-carboxylase] ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"B5D82_10115 fis; Fis family transcriptional regulator\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein"
				},
				{
					"name":"B5D82_01580 sigma-54-dependent Fis family transcriptional regulator\tK10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein"
				},
				{
					"name":"B5D82_03000 nitric oxide reductase transcription regulator\tK12266 norR; anaerobic nitric oxide reductase transcription regulator"
				},
				{
					"name":"B5D82_12735 XRE family transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"B5D82_14105 transcriptional regulator\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"B5D82_09870 transcriptional regulator\tK03764 metJ; MetJ family transcriptional regulator, methionine regulon repressor"
				},
				{
					"name":"B5D82_11600 putA; bifunctional proline dehydrogenase\/L-glutamate gamma-semialdehyde dehydrogenase\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]"
				}
				]
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"B5D82_05280 (4Fe-4S)-binding protein\tK19339 nosR; NosR\/NirI family transcriptional regulator, nitrous oxide reductase regulator"
				},
				{
					"name":"B5D82_06870 regulatory protein NosR\tK19339 nosR; NosR\/NirI family transcriptional regulator, nitrous oxide reductase regulator"
				},
				{
					"name":"B5D82_02725 transcriptional regulator\tK05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator"
				},
				{
					"name":"B5D82_08180 chromosome partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"B5D82_00315 arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"B5D82_11675 arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"B5D82_03150 DNA-binding transcriptional regulator TyrR\tK03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport"
				},
				{
					"name":"B5D82_03785 Fis family transcriptional regulator\tK03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport"
				},
				{
					"name":"B5D82_19280 transcriptional regulator\tK03567 gcvR; glycine cleavage system transcriptional repressor"
				},
				{
					"name":"B5D82_10975 paaX; phenylacetic acid degradation operon negative regulatory protein PaaX\tK02616 paaX; phenylacetic acid degradation operon negative regulatory protein"
				},
				{
					"name":"B5D82_03110 pspF; phage shock protein operon transcriptional activator\tK03974 pspF; psp operon transcriptional activator"
				},
				{
					"name":"B5D82_03125 pspC; PspC domain-containing protein\tK03973 pspC; phage shock protein C"
				},
				{
					"name":"B5D82_16700 hypothetical protein\tK06140 rnk; regulator of nucleoside diphosphate kinase"
				},
				{
					"name":"B5D82_12805 helix-turn-helix domain-containing protein\tK07733 alpA; prophage regulatory protein"
				},
				{
					"name":"B5D82_17710 AlpA family phage regulatory protein\tK07733 alpA; prophage regulatory protein"
				},
				{
					"name":"B5D82_06960 FMN-binding negative transcriptional regulator\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"B5D82_03955 DUF179 domain-containing protein\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"B5D82_11460 dksA; RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"B5D82_00950 nrdR; transcriptional regulator NrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"B5D82_00350 cell division\/cell wall cluster transcriptional repressor MraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}