{
	"name":"ccin01001",
	"children":[
	{
		"name":"Serine\/threonine kinases: AGC group",
		"children":[
		{
			"name":"PKA family",
			"children":[
			{
				"name":"107263245 cAMP-dependent protein kinase catalytic subunit alpha\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
			},
			{
				"name":"107274724 cAMP-dependent protein kinase catalytic subunit\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
			},
			{
				"name":"107264403 cAMP-dependent protein kinase catalytic subunit PRKX\tK19584 PRKX; protein kinase X [EC:2.7.11.11]"
			}
			]
		},
		{
			"name":"PKG family",
			"children":[
			{
				"name":"107265986 cGMP-dependent protein kinase, isozyme 2 forms cD4\/T1\/T3A\/T3B isoform X1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"107267830 cGMP-dependent protein kinase 1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"107267842 cGMP-dependent protein kinase, isozyme 1 isoform X1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			}
			]
		},
		{
			"name":"PKC family [OT]",
			"children":[
			{
				"name":"107268095 protein kinase C, brain isozyme isoform X2\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
			},
			{
				"name":"107262990 protein kinase C isoform X1\tK18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]"
			},
			{
				"name":"107272478 atypical protein kinase C isoform X1\tK06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PKN family",
			"children":[
			{
				"name":"107263321 serine\/threonine-protein kinase N isoform X1\tK23691 PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"AUR family [OT]",
			"children":[
			{
				"name":"107265907 aurora kinase C\tK11481 AURKA; aurora kinase A [EC:2.7.11.1]"
			},
			{
				"name":"107271098 aurora kinase B\tK11479 AURKB; aurora kinase B [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PDK1 family",
			"children":[
			{
				"name":"107264915 3-phosphoinositide-dependent protein kinase 1 isoform X1\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"AKT\/PKB family",
			"children":[
			{
				"name":"107273201 RAC serine\/threonine-protein kinase isoform X1\tK04456 AKT; RAC serine\/threonine-protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"SGK family [OT]"
		},
		{
			"name":"RSK family [OT]",
			"children":[
			{
				"name":"107275113 ribosomal protein S6 kinase 2 beta\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
			},
			{
				"name":"107269876 ribosomal protein S6 kinase alpha-5 isoform X2\tK04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]"
			},
			{
				"name":"107267208 ribosomal protein S6 kinase beta-1\tK04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]"
			},
			{
				"name":"107271599 ribosomal protein S6 kinase beta-1 isoform X1\tK04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]"
			},
			{
				"name":"107265786 ribosomal protein S6 kinase delta-1 isoform X1\tK20839 RSKL; ribosomal protein S6 kinase-like"
			}
			]
		},
		{
			"name":"NDR family",
			"children":[
			{
				"name":"107265537 serine\/threonine-protein kinase tricorner isoform X1\tK08790 STK38; serine\/threonine kinase 38 [EC:2.7.11.1]"
			},
			{
				"name":"107265350 serine\/threonine-protein kinase Warts\tK08791 LATS1_2; serine\/threonine-protein kinase LATS1\/2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAST family [OT]",
			"children":[
			{
				"name":"107267348 microtubule-associated serine\/threonine-protein kinase 3 isoform X1\tK08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]"
			},
			{
				"name":"107263277 serine\/threonine-protein kinase greatwall\tK16309 MASTL; serine\/threonine-protein kinase greatwall [EC:2.7.11.36]"
			}
			]
		},
		{
			"name":"YANK family",
			"children":[
			{
				"name":"107268667 serine\/threonine-protein kinase 32A isoform X1\tK08793 STK32; serine\/threonine kinase 32 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DMPK family [OT]",
			"children":[
			{
				"name":"107274905 rho-associated protein kinase 1 isoform X1\tK04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]"
			},
			{
				"name":"107273110 serine\/threonine-protein kinase Genghis Khan isoform X3\tK16307 CDC42BP; serine\/threonine-protein kinase MRCK [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"GRK family [OT]",
			"children":[
			{
				"name":"107271505 G protein-coupled receptor kinase 1 isoform X1\tK00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]"
			},
			{
				"name":"107263158 G protein-coupled receptor kinase 5 isoform X2\tK08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"107271583 serine\/threonine-protein kinase S6KL\tK17529 SGK494; uncharacterized serine\/threonine-protein kinase SgK494 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CAMK group",
		"children":[
		{
			"name":"CAMK1 family [OT]",
			"children":[
			{
				"name":"107271157 calcium\/calmodulin-dependent protein kinase type 1 isoform X1\tK08794 CAMK1; calcium\/calmodulin-dependent protein kinase I [EC:2.7.11.17]"
			},
			{
				"name":"107273926 calcium\/calmodulin-dependent protein kinase type IV\tK05869 CAMK4; calcium\/calmodulin-dependent protein kinase IV [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CAMK2 family",
			"children":[
			{
				"name":"107265085 calcium\/calmodulin-dependent protein kinase type II alpha chain isoform X33\tK04515 CAMK2; calcium\/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CAMKL family",
			"children":[
			{
				"name":"107270545 serine\/threonine kinase SAD-1\tK08796 BRSK; BR serine\/threonine kinase [EC:2.7.11.1]"
			},
			{
				"name":"107266515 serine\/threonine-protein kinase grp isoform X1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
			},
			{
				"name":"107269868 serine\/threonine-protein kinase MARK2 isoform X1\tK08798 MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]"
			},
			{
				"name":"107269036 maternal embryonic leucine zipper kinase\tK08799 MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]"
			},
			{
				"name":"107271326 serine\/threonine-protein kinase NIM1 isoform X1\tK16310 NIM1; serine\/threonine-protein kinase NIM1 [EC:2.7.11.1]"
			},
			{
				"name":"107271156 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]"
			},
			{
				"name":"107264330 serine\/threonine-protein kinase MARK2\tK16311 SIK2; serine\/threonine-protein kinase SIK2 [EC:2.7.11.1]"
			},
			{
				"name":"107264711 serine\/threonine-protein kinase SIK3 isoform X1\tK19009 SIK3; serine\/threonine-protein kinase SIK3 [EC:2.7.11.1]"
			},
			{
				"name":"107264018 MAP\/microtubule affinity-regulating kinase 4\tK08802 SNRK; SNF related kinase [EC:2.7.11.1]"
			},
			{
				"name":"107270678 serine\/threonine-protein kinase STK11 isoform X1\tK07298 STK11; serine\/threonine-protein kinase 11 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DAPK family",
			"children":[
			{
				"name":"107265801 LOW QUALITY PROTEIN: death-associated protein kinase 1\tK08803 DAPK; death-associated protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"107272644 serine\/threonine-protein kinase 17B\tK08804 STK17; serine\/threonine kinase 17 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DCAMKL family",
			"children":[
			{
				"name":"107269665 serine\/threonine-protein kinase DCLK1 isoform X1\tK08805 DCLK1_2; doublecortin-like kinase 1\/2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAPKAPK family [OT]",
			"children":[
			{
				"name":"107267395 MAP kinase-activated protein kinase 2 isoform X1\tK04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"107263570 MAP kinase-interacting serine\/threonine-protein kinase 1 isoform X1\tK04372 MKNK; MAP kinase interacting serine\/threonine kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MLCK family",
			"children":[
			{
				"name":"107273710 CBL-interacting serine\/threonine-protein kinase 23 isoform X1\tK00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]"
			},
			{
				"name":"107273400 LOW QUALITY PROTEIN: titin\tK12567 TTN; titin [EC:2.7.11.1]"
			},
			{
				"name":"107273401 uncharacterized protein LOC107273401 isoform X1\tK12567 TTN; titin [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PHK family",
			"children":[
			{
				"name":"107268633 phosphorylase b kinase gamma catalytic chain, skeletal muscle\/heart isoform isoform X1\tK00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]"
			}
			]
		},
		{
			"name":"PIM family [OT]"
		},
		{
			"name":"PKD family",
			"children":[
			{
				"name":"107274795 serine\/threonine-protein kinase D3 isoform X1\tK06070 PKD; protein kinase D [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PSK family"
		},
		{
			"name":"RAD53 family",
			"children":[
			{
				"name":"107268766 ovarian-specific serine\/threonine-protein kinase Lok isoform X1\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trio family [OT]"
		},
		{
			"name":"TSSK family",
			"children":[
			{
				"name":"107265846 testis-specific serine\/threonine-protein kinase 2\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			},
			{
				"name":"107266486 testis-specific serine\/threonine-protein kinase 4-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			},
			{
				"name":"107268086 testis-specific serine\/threonine-protein kinase 1-like\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CDPK family"
		},
		{
			"name":"CASK family",
			"children":[
			{
				"name":"107272883 peripheral plasma membrane protein CASK isoform X1\tK06103 CASK; calcium\/calmodulin-dependent serine protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trbl family",
			"children":[
			{
				"name":"107275091 tribbles homolog 2\tK08814 TRIB1_2; tribbles homolog 1\/2"
			}
			]
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CK1 group",
		"children":[
		{
			"name":"CK1 family [OT]",
			"children":[
			{
				"name":"107267539 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"107266362 casein kinase I isoform X1\tK08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]"
			},
			{
				"name":"107264921 casein kinase I isoform X1\tK08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TTBK family",
			"children":[
			{
				"name":"107263575 tau-tubulin kinase homolog Asator isoform X1\tK08815 TTBK; tau tubulin kinase [EC:2.7.11.26]"
			}
			]
		},
		{
			"name":"VRK family",
			"children":[
			{
				"name":"107263291 serine\/threonine-protein kinase VRK1\tK08816 VRK; vaccinia related kinase [EC:2.7.11.1]"
			},
			{
				"name":"107267416 serine\/threonine-protein kinase VRK1\tK08816 VRK; vaccinia related kinase [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CMGC group",
		"children":[
		{
			"name":"CDK family",
			"children":[
			{
				"name":"107264407 cyclin-dependent kinase 20\tK08817 CDK20; cyclin-dependent kinase 20 [EC:2.7.11.22]"
			},
			{
				"name":"107273308 cyclin-dependent kinase 11A isoform X1\tK08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]"
			},
			{
				"name":"107266789 cyclin-dependent kinase 1\tK02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"107265946 cyclin-dependent kinase 2 isoform X1\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
			},
			{
				"name":"107266722 cyclin-dependent-like kinase 5\tK02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]"
			},
			{
				"name":"107274614 cyclin-dependent kinase 4\tK02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]"
			},
			{
				"name":"107268272 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"107266473 cyclin-dependent kinase 8\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"107272089 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"107262950 cyclin-dependent kinase 10 isoform X1\tK02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]"
			},
			{
				"name":"107263442 cyclin-dependent kinase 12 isoform X1\tK08819 CDK12_13; cyclin-dependent kinase 12\/13 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"107274894 cyclin-dependent kinase 14\tK08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"MAPK family [OT]",
			"children":[
			{
				"name":"107271546 mitogen-activated protein kinase 1\tK04371 ERK; mitogen-activated protein kinase 1\/3 [EC:2.7.11.24]"
			},
			{
				"name":"107271015 mitogen-activated protein kinase 15 isoform X1\tK19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]"
			},
			{
				"name":"107268543 stress-activated protein kinase JNK isoform X1\tK04440 JNK; mitogen-activated protein kinase 8\/9\/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]"
			},
			{
				"name":"107268603 mitogen-activated protein kinase p38b isoform X1\tK04441 P38; p38 MAP kinase [EC:2.7.11.24]"
			},
			{
				"name":"107270001 serine\/threonine-protein kinase NLK\tK04468 NLK; nemo like kinase [EC:2.7.11.24]"
			}
			]
		},
		{
			"name":"GSK family [OT]",
			"children":[
			{
				"name":"107267207 glycogen synthase kinase-3 beta-like isoform X2\tK03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]"
			}
			]
		},
		{
			"name":"CLK family",
			"children":[
			{
				"name":"107264543 serine\/threonine-protein kinase Doa isoform X2\tK08823 CLK2_3; dual specificity protein kinase CLK2\/3 [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"CDKL family",
			"children":[
			{
				"name":"107262958 cyclin-dependent kinase-like 4 isoform X1\tK08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]"
			},
			{
				"name":"107263371 cyclin-dependent kinase-like 1 isoform X1\tK08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"DYRK family [OT]",
			"children":[
			{
				"name":"107264258 serine\/threonine-protein kinase minibrain\tK08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]"
			},
			{
				"name":"107264422 probable serine\/threonine-protein kinase dyrk2\tK18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]"
			},
			{
				"name":"107267428 dual specificity tyrosine-phosphorylation-regulated kinase 2\tK18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]"
			},
			{
				"name":"107266757 homeodomain-interacting protein kinase 2 isoform X6\tK08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"107273403 serine\/threonine-protein kinase PRP4 homolog isoform X1\tK08827 PRPF4B; serine\/threonine-protein kinase PRP4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RCK family [OT]",
			"children":[
			{
				"name":"107267153 serine\/threonine-protein kinase ICK isoform X1\tK08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]"
			},
			{
				"name":"107267377 probable serine\/threonine-protein kinase DDB_G0268078 isoform X2\tK08830 RAGE; renal tumor antigen [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"SRPK family [OT]",
			"children":[
			{
				"name":"107264902 SRSF protein kinase 3 isoform X1\tK15409 SRPK1; serine\/threonine-protein kinase SRPK1 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: STE group",
		"children":[
		{
			"name":"STE7 family",
			"children":[
			{
				"name":"107273912 dual specificity mitogen-activated protein kinase kinase dSOR1 isoform X1\tK04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]"
			},
			{
				"name":"107267810 dual specificity mitogen-activated protein kinase kinase 6\tK04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]"
			},
			{
				"name":"107267852 dual specificity mitogen-activated protein kinase kinase 4 isoform X3\tK04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]"
			},
			{
				"name":"107274219 dual specificity mitogen-activated protein kinase kinase 7\tK04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"STE20 family",
			"children":[
			{
				"name":"107267425 mitogen-activated protein kinase kinase kinase kinase 5 isoform X4\tK08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"107271923 serine\/threonine-protein kinase mig-15 isoform X1\tK08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]"
			},
			{
				"name":"107268033 myosin-IIIb isoform X1\tK08834 MYO3; myosin III [EC:2.7.11.1]"
			},
			{
				"name":"107275116 neither inactivation nor afterpotential protein C isoform X1\tK08834 MYO3; myosin III [EC:2.7.11.1]"
			},
			{
				"name":"107266366 serine\/threonine-protein kinase OSR1 isoform X1\tK08835 OXSR1; serine\/threonine-protein kinase OSR1\/STK39 [EC:2.7.11.1]"
			},
			{
				"name":"107270252 serine\/threonine-protein kinase PAK 2\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"107264215 serine\/threonine-protein kinase PAK mbt\tK05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"107268928 serine\/threonine-protein kinase 10 isoform X2\tK08836 SLK; STE20-like kinase [EC:2.7.11.1]"
			},
			{
				"name":"107271574 STE20-related kinase adapter protein alpha\tK08271 STRADA; STE20-related kinase adapter protein alpha"
			},
			{
				"name":"107267702 serine\/threonine-protein kinase 3 isoform X1\tK04412 STK3; serine\/threonine kinase 3"
			},
			{
				"name":"107273342 germinal center kinase 1 isoform X1\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]"
			},
			{
				"name":"107266611 serine\/threonine-protein kinase Tao\tK04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"STE11 family",
			"children":[
			{
				"name":"107264514 mitogen-activated protein kinase kinase kinase 4 isoform X1\tK04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]"
			},
			{
				"name":"107268205 mitogen-activated protein kinase kinase kinase 15 isoform X1\tK04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]"
			}
			]
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: TKL group",
		"children":[
		{
			"name":"IRAK family",
			"children":[
			{
				"name":"107266239 serine\/threonine-protein kinase pelle isoform X1\tK04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"107266242 serine\/threonine-protein kinase pelle isoform X1\tK04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"107270376 tubulin-specific chaperone C isoform X1\tK04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"LISK family [OT]",
			"children":[
			{
				"name":"107266945 LIM domain kinase 1 isoform X1\tK05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"LRRK family"
		},
		{
			"name":"MLK family",
			"children":[
			{
				"name":"107267944 mitogen-activated protein kinase kinase kinase 7 isoform X1\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]"
			},
			{
				"name":"107264314 mitogen-activated protein kinase kinase kinase 11 isoform X1\tK04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]"
			},
			{
				"name":"107273414 mitogen-activated protein kinase kinase kinase 12 isoform X2\tK04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]"
			},
			{
				"name":"107269960 integrin-linked protein kinase homolog pat-4\tK06272 ILK; integrin-linked kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RAF family [OT]",
			"children":[
			{
				"name":"107270964 raf homolog serine\/threonine-protein kinase Raf\tK04365 BRAF; B-Raf proto-oncogene serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"107263514 kinase suppressor of Ras 2 isoform X1\tK18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RIPK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: Other",
		"children":[
		{
			"name":"RGC family [OT]",
			"children":[
			{
				"name":"107266322 atrial natriuretic peptide receptor 1 isoform X1\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]"
			},
			{
				"name":"107270843 retinal guanylyl cyclase 2 isoform X1\tK12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]"
			}
			]
		},
		{
			"name":"BUB family",
			"children":[
			{
				"name":"107269786 uncharacterized protein LOC107269786 isoform X1\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Bud32 family",
			"children":[
			{
				"name":"107264614 EKC\/KEOPS complex subunit TP53RK\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CAMKK family",
			"children":[
			{
				"name":"107266646 uncharacterized protein LOC107266646 isoform X1\tK07359 CAMKK2; calcium\/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CDC7 family",
			"children":[
			{
				"name":"107273183 cell division cycle 7-related protein kinase isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CK2 family",
			"children":[
			{
				"name":"107275215 casein kinase II subunit alpha isoform X1\tK03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Haspin family",
			"children":[
			{
				"name":"107270063 uncharacterized protein PF11_0213\tK16315 GSG2; serine\/threonine-protein kinase haspin [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"IKK family [OT]",
			"children":[
			{
				"name":"107267930 inhibitor of nuclear factor kappa-B kinase subunit alpha\tK07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]"
			},
			{
				"name":"107267072 serine\/threonine-protein kinase TBK1 isoform X1\tK05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]"
			}
			]
		},
		{
			"name":"IRE family",
			"children":[
			{
				"name":"107264641 serine\/threonine-protein kinase\/endoribonuclease IRE1\tK08852 ERN1; serine\/threonine-protein kinase\/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]"
			}
			]
		},
		{
			"name":"MOS family",
			"children":[
			{
				"name":"107263307 serine\/threonine-protein kinase mos isoform X2\tK04367 MOS; proto-oncogene serine\/threonine-protein kinase mos [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NAK family [OT]",
			"children":[
			{
				"name":"107265347 BMP-2-inducible protein kinase isoform X1\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"107271482 cyclin-G-associated kinase\tK08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"107269261 serine\/threonine-protein kinase 16\tK08856 STK16; serine\/threonine kinase 16 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NEK family"
		},
		{
			"name":"NKF1 family",
			"children":[
			{
				"name":"107264376 serine\/threonine-protein kinase 10 isoform X1\tK08858 SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]"
			},
			{
				"name":"107264660 serine\/threonine-protein kinase SBK1\tK08858 SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF2 family"
		},
		{
			"name":"NKF3 family"
		},
		{
			"name":"NKF4 family"
		},
		{
			"name":"NKF5 family",
			"children":[
			{
				"name":"107274657 uncharacterized protein LOC107274657 isoform X1\tK17540 TEX14; inactive serine\/threonine-protein kinase TEX14"
			}
			]
		},
		{
			"name":"NRBP family",
			"children":[
			{
				"name":"107272517 nuclear receptor-binding protein homolog isoform X1\tK08875 NRBP; nuclear receptor-binding protein"
			}
			]
		},
		{
			"name":"PEK family [OT]",
			"children":[
			{
				"name":"107270978 eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1\tK16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"107262787 eIF-2-alpha kinase GCN2\tK16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PLK family [OT]",
			"children":[
			{
				"name":"107264373 serine\/threonine-protein kinase polo\tK06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]"
			},
			{
				"name":"107273614 serine\/threonine-protein kinase PLK1 isoform X1\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
			},
			{
				"name":"107266934 serine\/threonine-protein kinase PLK4\tK08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]"
			}
			]
		},
		{
			"name":"SCY1 family [OT]",
			"children":[
			{
				"name":"107269021 N-terminal kinase-like protein isoform X1\tK08876 SCYL1; SCY1-like protein 1"
			},
			{
				"name":"107263313 SCY1-like protein 2 isoform X1\tK17541 SCYL2; SCY1-like protein 2"
			},
			{
				"name":"107268883 SCY1-like protein 2\tK17541 SCYL2; SCY1-like protein 2"
			},
			{
				"name":"107267723 protein-associating with the carboxyl-terminal domain of ezrin\tK17542 SCYL3; SCY1-like protein 3"
			}
			]
		},
		{
			"name":"Slob family",
			"children":[
			{
				"name":"107265853 PX domain-containing protein kinase-like protein isoform X2\tK17543 PXK; PX domain-containing protein kinase-like protein"
			},
			{
				"name":"107268520 slowpoke-binding protein isoform X1\tK17543 PXK; PX domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TBCK family",
			"children":[
			{
				"name":"107272746 TBC domain-containing protein kinase-like protein\tK17544 TBCK; TBC domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TLK family",
			"children":[
			{
				"name":"107271502 serine\/threonine-protein kinase tousled-like 2 isoform X1\tK08864 TLK; tousled-like kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TOPK family",
			"children":[
			{
				"name":"107271145 lymphokine-activated killer T-cell-originated protein kinase\tK08865 PBK; PDZ-binding kinase [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"TTK family",
			"children":[
			{
				"name":"107268458 probable myosin light chain kinase DDB_G0279831\tK08866 TTK; serine\/threonine-protein kinase TTK\/MPS1 [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"ULK family [OT]",
			"children":[
			{
				"name":"107272646 serine\/threonine-protein kinase fused\tK06228 FU; fused [EC:2.7.11.1]"
			},
			{
				"name":"107268726 serine\/threonine-protein kinase unc-51\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
			},
			{
				"name":"107273906 serine\/threonine-protein kinase ULK3 isoform X1\tK21358 ULK3; serine\/threonine-protein kinase ULK3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"VPS15 family",
			"children":[
			{
				"name":"107268665 phosphoinositide 3-kinase regulatory subunit 4 isoform X1\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"WEE family",
			"children":[
			{
				"name":"107264813 wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Wnk family",
			"children":[
			{
				"name":"107268853 uncharacterized protein LOC107268853 isoform X1\tK08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"ABC1 family",
			"children":[
			{
				"name":"107262768 uncharacterized aarF domain-containing protein kinase 2\tK08869 ADCK; aarF domain-containing kinase"
			},
			{
				"name":"107265784 uncharacterized aarF domain-containing protein kinase 1\tK08869 ADCK; aarF domain-containing kinase"
			},
			{
				"name":"107265911 uncharacterized aarF domain-containing protein kinase 5 isoform X1\tK08869 ADCK; aarF domain-containing kinase"
			},
			{
				"name":"107268020 atypical kinase COQ8B, mitochondrial\tK08869 ADCK; aarF domain-containing kinase"
			}
			]
		},
		{
			"name":"Alpha family [OT]"
		},
		{
			"name":"BCR family"
		},
		{
			"name":"BRD family [OT]"
		},
		{
			"name":"FAST family"
		},
		{
			"name":"G11 family"
		},
		{
			"name":"H11 family"
		},
		{
			"name":"PDHK family [OT]",
			"children":[
			{
				"name":"107274616 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial\tK00898 PDK2_3_4; pyruvate dehydrogenase kinase 2\/3\/4 [EC:2.7.11.2]"
			}
			]
		},
		{
			"name":"PIKK family [OT]",
			"children":[
			{
				"name":"107271877 serine-protein kinase ATM isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
			},
			{
				"name":"107271382 serine\/threonine-protein kinase ATR isoform X1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
			},
			{
				"name":"107273275 serine\/threonine-protein kinase mTOR\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
			},
			{
				"name":"107265108 DNA-dependent protein kinase catalytic subunit isoform X1\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
			},
			{
				"name":"107267761 serine\/threonine-protein kinase SMG1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
			},
			{
				"name":"107270991 transformation\/transcription domain-associated protein\tK08874 TRRAP; transformation\/transcription domain-associated protein"
			}
			]
		},
		{
			"name":"RIO family [OT]",
			"children":[
			{
				"name":"107265643 serine\/threonine-protein kinase RIO1\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"107268279 serine\/threonine-protein kinase rio2\tK07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TAF1 family",
			"children":[
			{
				"name":"107271269 transcription initiation factor TFIID subunit 1 isoform X1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
			}
			]
		},
		{
			"name":"TIF1 family [OT]",
			"children":[
			{
				"name":"107268530 E3 ubiquitin-protein ligase TRIM33\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"107266317 protein mahjong\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
			},
			{
				"name":"107273149 dual serine\/threonine and tyrosine protein kinase isoform X1\tK16288 DSTYK; dual serine\/threonine and tyrosine protein kinase [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"Bacterial family"
		}
		]
	},
	{
		"name":"Receptor serine\/threonine kinases (RSTK): TKL group",
		"children":[
		{
			"name":"TGFBR1 family [OT]",
			"children":[
			{
				"name":"107270568 activin receptor type-1\tK04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]"
			},
			{
				"name":"107265058 bone morphogenetic protein receptor type-1B isoform X2\tK13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]"
			},
			{
				"name":"107265999 bone morphogenetic protein receptor type-1B\tK13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]"
			},
			{
				"name":"107267576 TGF-beta receptor type-1 isoform X2\tK04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]"
			}
			]
		},
		{
			"name":"TGFBR2 family [OT]",
			"children":[
			{
				"name":"107269068 activin receptor type-2A isoform X1\tK13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]"
			},
			{
				"name":"107275044 bone morphogenetic protein receptor type-2\tK04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]"
			},
			{
				"name":"107270321 growth\/differentiation factor 8 isoform X1\tK04669 TGFBRX; TGF-beta receptor, other"
			}
			]
		}
		]
	},
	{
		"name":"Receptor tyrosine kinases (RTK)",
		"children":[
		{
			"name":"EGFR family [OT]",
			"children":[
			{
				"name":"107273232 epidermal growth factor receptor isoform X1\tK04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"INSR family [OT]",
			"children":[
			{
				"name":"107271782 insulin-like receptor isoform X1\tK04527 INSR; insulin receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"PDGFR family [OT]"
		},
		{
			"name":"FGFR family [OT]",
			"children":[
			{
				"name":"107264528 tyrosine kinase receptor Cad96Ca\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"107274797 tyrosine-protein kinase receptor torso isoform X1\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"107271667 fibroblast growth factor receptor homolog 1 isoform X1\tK05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"VEGFR family [OT]",
			"children":[
			{
				"name":"107272921 vascular endothelial growth factor receptor 1 isoform X1\tK05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MET family"
		},
		{
			"name":"TRK family [OT]"
		},
		{
			"name":"EPH family [OT]",
			"children":[
			{
				"name":"107274562 ephrin type-B receptor 1 isoform X1\tK05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"AXL family"
		},
		{
			"name":"ALK family",
			"children":[
			{
				"name":"107267482 ALK tyrosine kinase receptor isoform X1\tK05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"TIE family"
		},
		{
			"name":"ROR family",
			"children":[
			{
				"name":"107267291 tyrosine-protein kinase transmembrane receptor Ror isoform X2\tK05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"107268134 high affinity nerve growth factor receptor isoform X1\tK05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"DDR family",
			"children":[
			{
				"name":"107263457 discoidin domain-containing receptor 2 isoform X1\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"107263510 discoidin domain-containing receptor 2 isoform X1\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"107263531 discoidin domain-containing receptor 2 isoform X1\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"107263533 discoidin domain-containing receptor 2 isoform X1\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			},
			{
				"name":"107263537 discoidin domain-containing receptor 2 isoform X1\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RET family",
			"children":[
			{
				"name":"107271995 proto-oncogene tyrosine-protein kinase receptor Ret isoform X1\tK05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"ROS family",
			"children":[
			{
				"name":"107263242 proto-oncogene tyrosine-protein kinase ROS isoform X3\tK05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"CCK family",
			"children":[
			{
				"name":"107271609 inactive tyrosine-protein kinase 7\tK05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RYK family",
			"children":[
			{
				"name":"107270466 tyrosine-protein kinase Drl\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			},
			{
				"name":"107270467 tyrosine-protein kinase Dnt isoform X1\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MUSK family",
			"children":[
			{
				"name":"107269548 tyrosine-protein kinase transmembrane receptor Ror2 isoform X1\tK05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"LMR family [OT]",
			"children":[
			{
				"name":"107264820 uncharacterized protein LOC107264820 isoform X1\tK17480 AATK; lemur tyrosine kinase 1 [EC:2.7.10.1]"
			}
			]
		}
		]
	},
	{
		"name":"Non-receptor tyrosine kinases",
		"children":[
		{
			"name":"ABL family",
			"children":[
			{
				"name":"107263465 tyrosine-protein kinase Abl isoform X1\tK06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"ACK family",
			"children":[
			{
				"name":"107266364 uncharacterized protein LOC107266364 isoform X1\tK08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]"
			},
			{
				"name":"107272522 tyrosine-protein kinase sid-3\tK08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]"
			}
			]
		},
		{
			"name":"CSK family",
			"children":[
			{
				"name":"107272181 tyrosine-protein kinase CSK isoform X1\tK05728 CSK; C-terminal Src kinase [EC:2.7.10.4]"
			}
			]
		},
		{
			"name":"FAK family",
			"children":[
			{
				"name":"107273475 uncharacterized protein LOC107273475 isoform X1\tK05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"FES family",
			"children":[
			{
				"name":"107265262 tyrosine-protein kinase Fer isoform X1\tK08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"JAK family [OT]",
			"children":[
			{
				"name":"107264899 tyrosine-protein kinase hopscotch isoform X2\tK11218 JAK3; Janus kinase 3 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SRC family",
			"children":[
			{
				"name":"107269379 tyrosine-protein kinase Src42A isoform X1\tK08892 FRK; fyn-related kinase [EC:2.7.10.2]"
			},
			{
				"name":"107264092 tyrosine-protein kinase Src64B isoform X1\tK05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"TEC family",
			"children":[
			{
				"name":"107266459 tyrosine-protein kinase Btk29A isoform X1\tK07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SYK family",
			"children":[
			{
				"name":"107271191 tyrosine-protein kinase Shark\tK17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial"
		}
		]
	},
	{
		"name":"Histidine kinases",
		"children":[
		{
			"name":"OmpR family"
		},
		{
			"name":"NarL family"
		},
		{
			"name":"Spo family [OT]"
		},
		{
			"name":"CitB family [OT]"
		},
		{
			"name":"LytTR family [OT]"
		},
		{
			"name":"NtrC family"
		},
		{
			"name":"CheA family [OT]"
		},
		{
			"name":"Cell cycle family [OT]"
		},
		{
			"name":"Lux family [OT]"
		},
		{
			"name":"LuxR family [OT]"
		},
		{
			"name":"Other"
		}
		]
	}
	]
}