{
	"name":"ccv03029",
	"children":[
	{
		"name":"Mitochondrial DNA transcription, translation, and replication factors",
		"children":[
		{
			"name":"Mitochondrial DNA-encoded proteins",
			"children":[
			{
				"name":"Mitochondrial respiratory chain complex I"
			},
			{
				"name":"Mitochondrial respiratory chain complex III",
				"children":[
				{
					"name":"CCV52592_1815 petB; ubiquinol cytochrome c oxidoreductase PetABC, cytochrome b subunit\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit"
				}
				]
			},
			{
				"name":"Cytochrome c oxidase"
			},
			{
				"name":"F-type ATPase"
			}
			]
		},
		{
			"name":"Mitochondrial transcription and translation factors",
			"children":[
			{
				"name":"Mitochondrial RNA polymerase"
			},
			{
				"name":"Mitochondrial transcription factors"
			},
			{
				"name":"Mitochondrial translation factors",
				"children":[
				{
					"name":"CCV52592_0355 infB; translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"CCV52592_0329 infC; translation initiation factor IF-3\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"CCV52592_1261 tsf; translation elongation factor EF-Ts\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"CCV52592_0173 tuf; translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"CCV52592_0189 fusA; translation elongation factor EF-G\tK02355 fusA; elongation factor G"
				}
				]
			},
			{
				"name":"RNase MRP"
			},
			{
				"name":"Mitochondrial ribonuclease P"
			},
			{
				"name":"Other mitochondrial DNA transcription and translation factors",
				"children":[
				{
					"name":"CCV52592_1972 era; GTP-binding protein\tK03595 era; GTPase"
				},
				{
					"name":"CCV52592_0484 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"CCV52592_0710 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"CCV52592_0465 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"CCV52592_1254 argS; arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"CCV52592_0978 gatA; Glu-tRNA(Gln) amidotransferase, subunit A\tK02433 gatA; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"CCV52592_0791 gatB; Glu-tRNA(Gln) amidotransferase, subunit B\tK02434 gatB; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"CCV52592_0997 gatC; Glu-tRNA(Gln) amidotransferase, subunit C\tK02435 gatC; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]"
				}
				]
			}
			]
		},
		{
			"name":"Mitochondrial DNA replication factors",
			"children":[
			{
				"name":"Mitochondrial DNA polymerase"
			},
			{
				"name":"Mitochondrial DNA maintenance factors",
				"children":[
				{
					"name":"CCV52592_1856 putative helicase, PIF1 family (DUF889 domain)\tK15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"Other Mitochondrial DNA replication factors",
				"children":[
				{
					"name":"CCV52592_0058 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"CCV52592_1586 ssb; single-stranded DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Mitochondrial protein import machinery",
		"children":[
		{
			"name":"Endoplasmic reticulum membrane and cytosol",
			"children":[
			{
				"name":"ER-mitochondria encounter structure (ERMES) complex"
			},
			{
				"name":"Other ER-memrane and cytosol factors"
			}
			]
		},
		{
			"name":"Outer membrane",
			"children":[
			{
				"name":"Transporter outer membrane (TOM) complex"
			},
			{
				"name":"TOB\/SAM complex",
				"children":[
				{
					"name":"CCV52592_1757 beta-barrel assembly machinery complex, BamA\/YaeT protein\tK07277 SAM50; outer membrane protein insertion porin family"
				}
				]
			},
			{
				"name":"MIM complex"
			},
			{
				"name":"Porin"
			},
			{
				"name":"Other outer membrane factor"
			}
			]
		},
		{
			"name":"Inter membrane space",
			"children":[
			{
				"name":"Transporter inner membrane (TIM) 9\/10 complex"
			},
			{
				"name":"TIM8\/13 complex"
			},
			{
				"name":"Mitochondrial intermembrane space assembly (MIA) complex"
			}
			]
		},
		{
			"name":"Inner mambrane",
			"children":[
			{
				"name":"MICOS complex"
			},
			{
				"name":"MICOS complex (yeast)"
			},
			{
				"name":"TIM22 complex"
			},
			{
				"name":"TIM23 complex"
			},
			{
				"name":"Mitochondrial calcium uniporter complex"
			},
			{
				"name":"Other inner membrane factors"
			}
			]
		},
		{
			"name":"Matrix",
			"children":[
			{
				"name":"MMC\/PAM proteins",
				"children":[
				{
					"name":"CCV52592_0148 dnaK; DnaK system heat shock chaperone\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"CCV52592_0150 grpE; DnaK system nucleotide exchange factor GrpE\tK03687 GRPE; molecular chaperone GrpE"
				}
				]
			},
			{
				"name":"Other matrix factors",
				"children":[
				{
					"name":"CCV52592_0308 groEL; 60 kD chaperonin (cpn60)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"CCV52592_0309 groES; 10 kD chaperonin (cpn10)\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"CCV52592_1361 dnaJ; DnaK system heat shock co-chaperone\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"CCV52592_1984 putative protein (DnaJ domain)\tK03686 dnaJ; molecular chaperone DnaJ"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Mitochondrial quality control factors",
		"children":[
		{
			"name":"Regulator of mitochondrial biogenesis",
			"children":[
			{
				"name":"Ubiquitas transcription factors",
				"children":[
				{
					"name":"CCV52592_0189 fusA; translation elongation factor EF-G\tK02355 fusA; elongation factor G"
				}
				]
			},
			{
				"name":"Nuclear respiratory factors"
			},
			{
				"name":"Coactivators"
			},
			{
				"name":"Proteins involved in Fe-S cluster biogenesis",
				"children":[
				{
					"name":"CCV52592_1770 iscS; cysteine desulfurase\/aminotransferase (IscS\/NifS)\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"CCV52592_0148 dnaK; DnaK system heat shock chaperone\tK04043 dnaK; molecular chaperone DnaK"
				}
				]
			},
			{
				"name":"Other regulator of mitochondrial biogenesis"
			}
			]
		},
		{
			"name":"Mitochondrial respiratory chain complex assembly factors",
			"children":[
			{
				"name":"Complex-I assembly factors",
				"children":[
				{
					"name":"CCV52592_0204 mrp; ATP\/GTP-binding protein\tK03593 mrp; ATP-binding protein involved in chromosome partitioning"
				}
				]
			},
			{
				"name":"Complex-II assembly factors"
			},
			{
				"name":"Complex-III assembly factors"
			},
			{
				"name":"Complex-IV assembly factors",
				"children":[
				{
					"name":"CCV52592_1831 oxaA; membrane protein insertase, YidC\/Oxa1 family\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"CCV52592_1941 cytochrome oxidase biogenesis protein, Sco1\/SenC\/PrrC family\tK07152 SCO1; protein SCO1"
				}
				]
			},
			{
				"name":"Complex-V assembly factors"
			}
			]
		},
		{
			"name":"Mitochondrial dynamics",
			"children":[
			{
				"name":"Fission and Fusion factors"
			},
			{
				"name":"Actin cytoskeleton organization"
			},
			{
				"name":"Mitochondrial movement"
			},
			{
				"name":"Retention of mitochondria"
			},
			{
				"name":"Morphogenesis factors"
			}
			]
		},
		{
			"name":"Mitophagy factors",
			"children":[
			{
				"name":"Autophagy-related proteins"
			},
			{
				"name":"Parkin-dependent mechanism factors"
			},
			{
				"name":"Parkin-independent mechanism factors",
				"children":[
				{
					"name":"CCV52592_1997 htpG; chaperone protein HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"Other mitophagy factors"
			}
			]
		}
		]
	}
	]
}