{
	"name":"cdk03051",
	"children":[
	{
		"name":"Eukaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"alpha type subunits",
				"children":[
				{
					"name":"105094163 PSMA6; proteasome subunit alpha type-6\tK02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]"
				},
				{
					"name":"105092322 PSMA2; proteasome subunit alpha type-2\tK02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]"
				},
				{
					"name":"105087216 PSMA4; proteasome subunit alpha type-4\tK02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]"
				},
				{
					"name":"105086586 PSMA8; proteasome subunit alpha-type 8\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"105095668 PSMA7; proteasome subunit alpha type-7 isoform X1\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"105085640 PSMA5; proteasome subunit alpha type-5 isoform X1\tK02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]"
				},
				{
					"name":"105086687 PSMA1; proteasome subunit alpha type-1\tK02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
				},
				{
					"name":"105086238 PSMA3; proteasome subunit alpha type-3\tK02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]"
				}
				]
			},
			{
				"name":"beta type subunits",
				"children":[
				{
					"name":"105101478 PSMB6; proteasome subunit beta type-6 isoform X1\tK02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]"
				},
				{
					"name":"105092636 PSMB7; proteasome subunit beta type-7 isoform X1\tK02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"105106941 PSMB3; proteasome subunit beta type-3\tK02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]"
				},
				{
					"name":"105086959 PSMB2; proteasome subunit beta type-2\tK02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]"
				},
				{
					"name":"105096978 PSMB5; proteasome subunit beta type-5\tK02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]"
				},
				{
					"name":"105093880 PSMB1; proteasome subunit beta type-1\tK02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]"
				},
				{
					"name":"105103219 PSMB4; proteasome subunit beta type-4\tK02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]"
				},
				{
					"name":"105101405 PSMB8; proteasome subunit beta type-8\tK02740 PSMB8; 20S proteasome subunit beta 8 [EC:3.4.25.1]"
				},
				{
					"name":"105101404 PSMB9; proteasome subunit beta type-9\tK02741 PSMB9; 20S proteasome subunit beta 9 [EC:3.4.25.1]"
				},
				{
					"name":"105088422 PSMB10; proteasome subunit beta type-10 isoform X1\tK02733 PSMB10; 20S proteasome subunit beta 10 [EC:3.4.25.1]"
				},
				{
					"name":"105096979 PSMB11; proteasome subunit beta type-11\tK11598 PSMB11; 20S proteasome subunit beta 11 [EC:3.4.25.1]"
				}
				]
			}
			]
		},
		{
			"name":"Regulatory particles",
			"children":[
			{
				"name":"PA700 (19S proteasome)",
				"children":[
				{
					"name":"ATPase subunits",
					"children":[
					{
						"name":"105093016 PSMC2; 26S proteasome regulatory subunit 7\tK03061 PSMC2; 26S proteasome regulatory subunit T1"
					},
					{
						"name":"105096017 PSMC1; 26S proteasome regulatory subunit 4\tK03062 PSMC1; 26S proteasome regulatory subunit T2"
					},
					{
						"name":"105093331 PSMC4; 26S proteasome regulatory subunit 6B\tK03063 PSMC4; 26S proteasome regulatory subunit T3"
					},
					{
						"name":"105091425 PSMC6; 26S proteasome regulatory subunit 10B isoform X1\tK03064 PSMC6; 26S proteasome regulatory subunit T4"
					},
					{
						"name":"105106880 PSMC3; 26S proteasome regulatory subunit 6A isoform X1\tK03065 PSMC3; 26S proteasome regulatory subunit T5"
					},
					{
						"name":"105090405 PSMC5; 26S proteasome regulatory subunit 8 isoform X1\tK03066 PSMC5; 26S proteasome regulatory subunit T6"
					}
					]
				},
				{
					"name":"non-ATPase subunits",
					"children":[
					{
						"name":"105085877 PSMD2; 26S proteasome non-ATPase regulatory subunit 2\tK03028 PSMD2; 26S proteasome regulatory subunit N1"
					},
					{
						"name":"105093755 PSMD1; 26S proteasome non-ATPase regulatory subunit 1 isoform X1\tK03032 PSMD1; 26S proteasome regulatory subunit N2"
					},
					{
						"name":"105099032 PSMD3; 26S proteasome non-ATPase regulatory subunit 3\tK03033 PSMD3; 26S proteasome regulatory subunit N3"
					},
					{
						"name":"105102519 PSMD9; 26S proteasome non-ATPase regulatory subunit 9 isoform X2\tK06693 PSMD9; 26S proteasome regulatory subunit N4"
					},
					{
						"name":"105092316 PSMD12; 26S proteasome non-ATPase regulatory subunit 12\tK03035 PSMD12; 26S proteasome regulatory subunit N5"
					},
					{
						"name":"105088223 PSMD11; 26S proteasome non-ATPase regulatory subunit 11\tK03036 PSMD11; 26S proteasome regulatory subunit N6"
					},
					{
						"name":"105094369 PSMD6; 26S proteasome non-ATPase regulatory subunit 6\tK03037 PSMD6; 26S proteasome regulatory subunit N7"
					},
					{
						"name":"105088390 PSMD7; 26S proteasome non-ATPase regulatory subunit 7\tK03038 PSMD7; 26S proteasome regulatory subunit N8"
					},
					{
						"name":"105105733 PSMD13; 26S proteasome non-ATPase regulatory subunit 13 isoform X2\tK03039 PSMD13; 26S proteasome regulatory subunit N9"
					},
					{
						"name":"105103211 PSMD4; 26S proteasome non-ATPase regulatory subunit 4 isoform X1\tK03029 PSMD4; 26S proteasome regulatory subunit N10"
					},
					{
						"name":"105093692 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 isoform X2\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
					},
					{
						"name":"105096924 PSMD8; 26S proteasome non-ATPase regulatory subunit 8\tK03031 PSMD8; 26S proteasome regulatory subunit N12"
					},
					{
						"name":"105095674 ADRM1; proteasomal ubiquitin receptor ADRM1 isoform X1\tK06691 RPN13; 26S proteasome regulatory subunit N13"
					},
					{
						"name":"105104518 PSMD5; 26S proteasome non-ATPase regulatory subunit 5 isoform X1\tK06692 PSMD5; 26S proteasome non-ATPase regulatory subunit 5"
					},
					{
						"name":"105095421 PSMD10; 26S proteasome non-ATPase regulatory subunit 10 isoform X1\tK06694 PSMD10; 26S proteasome non-ATPase regulatory subunit 10"
					}
					]
				}
				]
			},
			{
				"name":"PA28 (11S REG)",
				"children":[
				{
					"name":"105102413 PSME1; proteasome activator complex subunit 1\tK06696 PSME1; proteasome activator subunit 1 (PA28 alpha)"
				},
				{
					"name":"105102414 PSME2; proteasome activator complex subunit 2\tK06697 PSME2; proteasome activator subunit 2 (PA28 beta)"
				},
				{
					"name":"105090481 PSME3; proteasome activator complex subunit 3\tK06698 PSME3; proteasome activator subunit 3 (PA28 gamma)"
				}
				]
			},
			{
				"name":"PA200",
				"children":[
				{
					"name":"105097697 PSME4; proteasome activator complex subunit 4 isoform X1\tK06699 PSME4; proteasome activator subunit 4"
				}
				]
			},
			{
				"name":"PI31",
				"children":[
				{
					"name":"105104302 PSMF1; proteasome inhibitor PI31 subunit\tK06700 PSMF1; proteasome inhibitor subunit 1 (PI31)"
				}
				]
			}
			]
		},
		{
			"name":"Assembling factors",
			"children":[
			{
				"name":"Assembling chaperones",
				"children":[
				{
					"name":"105086587 POMP; proteasome maturation protein\tK11599 POMP; proteasome maturation protein"
				},
				{
					"name":"105100728 PSMG1; LOW QUALITY PROTEIN: proteasome assembly chaperone 1\tK11875 PSMG1; proteasome assembly chaperone 1"
				},
				{
					"name":"105086471 PSMG2; proteasome assembly chaperone 2 isoform X4\tK11876 PSMG2; proteasome assembly chaperone 2"
				},
				{
					"name":"105105859 PSMG3; proteasome assembly chaperone 3\tK11877 PSMG3; proteasome assembly chaperone 3"
				},
				{
					"name":"105098614 PSMG4; proteasome assembly chaperone 4\tK11878 PSMG4; proteasome assembly chaperone 4"
				}
				]
			},
			{
				"name":"Other assembling factors",
				"children":[
				{
					"name":"105093288 EIF3E; eukaryotic translation initiation factor 3 subunit E\tK03250 EIF3E; translation initiation factor 3 subunit E"
				},
				{
					"name":"105087446 LOW QUALITY PROTEIN: heat shock 70 kDa protein 1B\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"105087447 heat shock 70 kDa protein 1-like isoform X1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"105094503 HSPA8; heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"105105187 HSPA6; heat shock 70 kDa protein 6\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"116147648 heat shock 70 kDa protein 1B\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"105086191 HSPA2; heat shock-related 70 kDa protein 2\tK26598 HSPA2; heat shock 70kDa protein 2"
				},
				{
					"name":"105088639 HSP90AB1; heat shock protein HSP 90-beta\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"105103462 HSP90AA1; heat shock protein HSP 90-alpha\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"105101111 IFNG; interferon gamma\tK04687 IFNG; interferon gamma"
				},
				{
					"name":"105088392 NOB1; RNA-binding protein NOB1\tK11883 NOB1; RNA-binding protein NOB1"
				},
				{
					"name":"116157511 PNO1; RNA-binding protein PNO1\tK11884 PNO1; RNA-binding protein PNO1"
				}
				]
			}
			]
		},
		{
			"name":"Proteasome interacting proteins (PIPs)",
			"children":[
			{
				"name":"UBL-UBA shuttle proteins",
				"children":[
				{
					"name":"105087923 RAD23B; UV excision repair protein RAD23 homolog B\tK10839 RAD23; UV excision repair protein RAD23"
				},
				{
					"name":"105100759 RAD23A; UV excision repair protein RAD23 homolog A isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
				},
				{
					"name":"105093069 UBQLN2; ubiquilin-2\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"105097938 UBQLN3; ubiquilin-3\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"105100490 UBQLN1; ubiquilin-1 isoform X1\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"105105661 UBQLN4; ubiquilin-4\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"105097939 ubiquilin-1-like\tK22254 UBQLNL; ubiquilin-like protein"
				},
				{
					"name":"105098008 UBQLNL; ubiquilin-like protein\tK22254 UBQLNL; ubiquilin-like protein"
				},
				{
					"name":"105103705 DDI1; protein DDI1 homolog 1\tK11885 DDI; DNA damage-inducible protein [EC:3.4.23.-]"
				},
				{
					"name":"105107060 DDI2; protein DDI1 homolog 2 isoform X4\tK11885 DDI; DNA damage-inducible protein [EC:3.4.23.-]"
				},
				{
					"name":"105098684 NUB1; NEDD8 ultimate buster 1\tK29014 NUB1; NEDD8 ultimate buster 1"
				}
				]
			},
			{
				"name":"Other PIPs",
				"children":[
				{
					"name":"105096424 ECPAS; proteasome adapter and scaffold protein ECM29 isoform X1\tK11886 ECM29; proteasome component ECM29"
				},
				{
					"name":"105096932 PAAF1; proteasomal ATPase-associated factor 1 isoform X1\tK11887 PAAF1; proteasomal ATPase-associated factor 1"
				},
				{
					"name":"105090465 PSMC3IP; homologous-pairing protein 2 homolog isoform X3\tK06695 PSMC3IP; 26S proteasome regulatory subunit, ATPase 3, interacting protein"
				},
				{
					"name":"105086229 JKAMP; JNK1\/MAPK8-associated membrane protein isoform X1\tK28966 JKAMP; JNK1\/MAPK8-associated membrane protein"
				},
				{
					"name":"105104112 MIDN; midnolin isoform X1\tK29091 MIDN; midnolin"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)"
		},
		{
			"name":"Bacterial regulatory particles"
		},
		{
			"name":"Archaeal regulatory particles"
		}
		]
	}
	]
}