{
	"name":"cdr03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins"
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"CDHC03_1343 oxyR; LysR-family transcriptional regulator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"CDHC03_0997 lysG; LysR-family transcriptional regulator\tK05596 argP; LysR family transcriptional regulator, arginine and lysine transport system\/DNA replication regulator"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"CDHC03_1350 sugR; DeoR-family transcriptional regulator\tK03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"CDHC03_1352 fruR; DeoR-family transcriptional regulator\tK03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"CDHC03_0580 LacI-family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"CDHC03_2123 farR; GntR-family transcriptional regulator\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"CDHC03_1972 putative transcriptional regulator\tK14348 lldR; GntR family transcriptional regulator, L-lactate dehydrogenase operon regulator"
				},
				{
					"name":"CDHC03_0154 GntR family regulator\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"CDHC03_1188 acnR; TetR-famlily transcriptional regulator\tK21962 acnR; TetR\/AcrR family transcriptional regulator, transcriptional repressor of aconitase"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family"
			},
			{
				"name":"LuxR family",
				"children":[
				{
					"name":"CDHC03_1771 ramA; LuxR-family transcriptional regulator\tK21685 ramA; LuxR family transcriptional regulator, regulator of acetate metabolism"
				}
				]
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"CDHC03_0096 MarR-family transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"CDHC03_2011 hspR; heat shock protein regulator\tK13640 hspR; MerR family transcriptional regulator, heat shock protein HspR"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"CDHC03_1608 zur; zinc uptake regulatory protein\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				}
				]
			},
			{
				"name":"IclR family"
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"CDHC03_0236 glxR; CRP\/Fnr-family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				}
				]
			},
			{
				"name":"Rrf2 family"
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"CDHC03_0345 glyR; ArsR-family transcriptional regulator\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family",
				"children":[
				{
					"name":"CDHC03_0298 ramB; HTH3-family transcriptional regulator\tK07110 ramB; XRE family transcriptional regulator, fatty acid utilization regulator"
				},
				{
					"name":"CDHC03_1377 clgR; HTH3-family transcriptional regulator\tK27043 clgR; XRE family transcriptional regulator, stress-response regulator"
				}
				]
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"CDHC03_1336 dtxR; diphtheria toxin repressor\tK26252 dtxR; DtxR family transcriptional regulator, iron-dependent repressor"
				},
				{
					"name":"CDHC03_0543 mntR; iron-dependent repressor ideR\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"CDHC03_0585 birA; biotin-protein ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"CDHC03_2199 hypothetical protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"CDHC03_0057 putative regulatory protein\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"CDHC03_0120 hypothetical protein\tK18918 relB; RHH-type transcriptional regulator, rel operon repressor \/ antitoxin RelB"
				},
				{
					"name":"CDHC03_2096 hypothetical protein\tK18918 relB; RHH-type transcriptional regulator, rel operon repressor \/ antitoxin RelB"
				}
				]
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family",
				"children":[
				{
					"name":"CDHC03_1054 putative transcription antiterminator\tK03488 licT; beta-glucoside operon transcriptional antiterminator"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"CDHC03_0232 whcA; putative transcriptional regulator\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"CDHC03_0609 whiB2; putative transcriptional regulator\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"CDHC03_0637 whcE; putative transcriptional regulator\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"CDHC03_2263 parB; chromosome partitioning protein B\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"CDHC03_1835 carD; putative transcription factor\tK07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription"
				},
				{
					"name":"CDHC03_1076 argR; arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"CDHC03_1619 hrcA; heat-inducible transcription repressor\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"CDHC03_0200 putative regulatory protein\tK05346 deoR; deoxyribonucleoside regulator"
				},
				{
					"name":"CDHC03_1238 pyrR; pyrimidine regulatory protein\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"CDHC03_2254 hypothetical protein\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"CDHC03_1346 nrdR; transcriptional regulator NrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"CDHC03_1519 mraZ; cell division protein MraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}
